Page last updated: 2024-09-03

bw 245c and alprostadil

bw 245c has been researched along with alprostadil in 7 studies

Compound Research Comparison

Studies
(bw 245c)
Trials
(bw 245c)
Recent Studies (post-2010)
(bw 245c)
Studies
(alprostadil)
Trials
(alprostadil)
Recent Studies (post-2010) (alprostadil)
963107,136864761

Protein Interaction Comparison

ProteinTaxonomybw 245c (IC50)alprostadil (IC50)
Multidrug resistance-associated protein 4Homo sapiens (human)2.3
Solute carrier organic anion transporter family member 2B1Rattus norvegicus (Norway rat)0.0358

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19902 (28.57)18.7374
1990's2 (28.57)18.2507
2000's3 (42.86)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hirata, M; Kiriyama, M; Kobayashi, T; Narumiya, S; Sugimoto, Y; Ushikubi, F1
Abramovitz, M; Ford-Hutchinson, AW; Metters, KM; Wright, DH1
Hamid, S; Lidbury, P; Rosam, AC; Whittle, BJ1
Kakkar, VV; Zahavi, J; Zahavi, M1
Heinemann, A; Holzer, P; Peskar, BA; Shahbazian, A1
Araldi, GL; Brugger, N; Kim, NN; Palmer, SS; Traish, AM1
Bing, N; Cox, RF; Gauthier, J; Jensen, D; Johnson, EN; Kostura, M; Murray, DL; Sorensen, SD; Vanderwall, D; Wang, P; Xu, Z1

Reviews

1 review(s) available for bw 245c and alprostadil

ArticleYear
Specificity between the anti-aggregatory actions of prostacyclin, prostaglandin E1 and D2 on platelets.
    Advances in experimental medicine and biology, 1985, Volume: 192

    Topics: Adenylyl Cyclases; Alprostadil; Animals; Cell Membrane; Epoprostenol; Humans; Hydantoins; Platelet Aggregation; Prostaglandin D2; Prostaglandins D; Prostaglandins, Synthetic; Radioligand Assay; Receptors, Epoprostenol; Receptors, Immunologic; Receptors, Prostaglandin; Receptors, Prostaglandin E; Species Specificity; Structure-Activity Relationship

1985

Other Studies

6 other study(ies) available for bw 245c and alprostadil

ArticleYear
Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells.
    British journal of pharmacology, 1997, Volume: 122, Issue:2

    Topics: Animals; CHO Cells; Cricetinae; Ligands; Mice; Prostaglandins; Receptors, Prostaglandin; Transfection

1997
Characterization of the recombinant human prostanoid DP receptor and identification of L-644,698, a novel selective DP agonist.
    British journal of pharmacology, 1998, Volume: 123, Issue:7

    Topics: Adenine Nucleotides; Benzoates; Binding, Competitive; Cell Line; Cyclic AMP; Dinoprostone; Guanine Nucleotides; Humans; Kinetics; Receptors, Immunologic; Receptors, Prostaglandin; Recombinant Proteins; Thiazoles; Thiazolidines; Tritium

1998
Effect of adenyl-cyclase activators, phosphodiesterase inhibitors and pyridoxal-5-phosphate on platelet aggregation and adenosine-3'-5'-cyclic monophosphate accumulation.
    Thrombosis and haemostasis, 1984, Oct-31, Volume: 52, Issue:2

    Topics: Adenylyl Cyclases; Adult; Alprostadil; Blood Platelets; Cyclic AMP; Dipyridamole; Female; Humans; Hydantoins; Male; Middle Aged; Papaverine; Phosphodiesterase Inhibitors; Platelet Aggregation; Prostaglandins E; Pyridoxal Phosphate; Theophylline

1984
Differential peristaltic motor effects of prostanoid (DP, EP, IP, TP) and leukotriene receptor agonists in the guinea-pig isolated small intestine.
    British journal of pharmacology, 2002, Volume: 137, Issue:7

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Alprostadil; Animals; Bridged Bicyclo Compounds, Heterocyclic; Dinoprostone; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Female; Guinea Pigs; Hydantoins; Hydrazines; Iloprost; In Vitro Techniques; Intestine, Small; Leukotriene Antagonists; Leukotriene D4; Male; Oxazepines; Peristalsis; Prostaglandin D2; Prostaglandins A; Receptors, Leukotriene; Receptors, Prostaglandin; Xanthenes; Xanthones; Yohimbine

2002
Pharmacological and functional characterization of novel EP and DP receptor agonists: DP1 receptor mediates penile erection in multiple species.
    The journal of sexual medicine, 2008, Volume: 5, Issue:2

    Topics: Aged; Alprostadil; Animals; Binding Sites; Blood Pressure; Dose-Response Relationship, Drug; Humans; Hydantoins; In Vitro Techniques; Injections, Intravenous; Male; Middle Aged; Muscle, Smooth; Penile Erection; Phenylephrine; Phosphodiesterase Inhibitors; Prostaglandin D2; Rabbits; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Species Specificity; Vasodilator Agents

2008
Functional antagonism of IL-1alpha induced gene expression profiles define the cAMP/PKA pathway as a unique regulator of IL-1alpha signaling networks.
    Journal of receptor and signal transduction research, 2009, Volume: 29, Issue:5

    Topics: Alprostadil; Anti-Ulcer Agents; Calcium; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Fibroblasts; Gene Expression Profiling; Humans; Hydantoins; I-kappa B Kinase; Iloprost; Interleukin-1alpha; JNK Mitogen-Activated Protein Kinases; Lung; MAP Kinase Kinase Kinases; Misoprostol; Oligonucleotide Array Sequence Analysis; p38 Mitogen-Activated Protein Kinases; Platelet Aggregation Inhibitors; Prostaglandins E, Synthetic; Receptors, G-Protein-Coupled; Receptors, Prostaglandin; Signal Transduction

2009