butyric acid and trichostatin a

butyric acid has been researched along with trichostatin a in 68 studies

Research

Studies (68)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's19 (27.94)18.2507
2000's18 (26.47)29.6817
2010's25 (36.76)24.3611
2020's6 (8.82)2.80

Authors

AuthorsStudies
Bello, SH; Liénard, BM; McDonough, MA; Mecinović, J; Ng, SS; Oppermann, U; Rose, NR; Schofield, CJ; Sun, Z1
Bora-Tatar, G; Dalkara, S; Dayangaç-Erden, D; Demir, AS; Erdem-Yurter, H; Yelekçi, K1
Arora, S; Chaturvedi, A; Heuser, M; Joshi, G; Kumar, R; Patil, S1
Alfano, AI; Barone, S; Brindisi, M; Cassese, E; Summa, V1
Matsushiro, A; Miyashita, T; Morita, T; Nishimune, Y; Nozaki, M; Yamamoto, H1
Arts, J; Grimbergen, J; Kooistra, T; Lansink, M; Toet, KH1
Almouzni, G; Dimitrov, S; Khochbin, S; Wolffe, AP1
Beppu, T; Bode, J; Klehr-Wirth, D; Schlake, T; Yoshida, M1
Barbie, DA; Hirai, TH; Howard, BH; Ogryzko, VV; Russanova, VR1
Doi, S; Hanmyou, F; Matsunaga, T; Nakamura, Y; Sakata, K; Yamamoto, I1
Furukubo, T; Kariya, K; Lee, E; Miyabe, T; Yamauchi, A1
Huang, N; Katz, JP; Martin, DR; Wu, GD1
Aranda, A; Castillo, AI; Garcia-Villalba, P; Jimenez-Lara, AM1
Bailey, EC; Chen, WY; Dong, JY; McCune, SL; Townes, TM1
Eastman, A; McBain, JA; Mueller, GC; Nobel, CS1
Chen, ZJ; Pikaard, CS1
Appleton, S; Edmonds, B; James, R; Medina, V; Young, GP; Zalewski, PD1
Fusunyan, RD; Lee, J; MacDermott, RP; Ohno, Y; Sanderson, IR1
Llorente, A; Rapak, A; Sandvig, K; Schmid, SL; van Deurs, B1
Al-Abed, Y; Emiliani, S; Fischle, W; Van Lint, C; Verdin, E1
Hayashi, H; Komatsu, Y1
Chen, HY; Davie, JR; Holth, LT; Sun, JM; Walia, H1
Dangond, F; Gullans, SR1
Li, J; Noguchi, CT; Schechter, AN; Smith, RD1
Barath, P; Hodny, Z; Li, R; Nelson, BD1
Kim, HS; Lee, JY; Park, J; Park, JB; Shin, JY1
Andoh, A; Bamba, T; Fujiyama, Y; Shimada, M1
Brown, G; Campbell, MJ; Driver, PM; Edwards, CE; Engel, J; Moore, JS; Rashid, SF; Uskokovic, MR; Walker, E1
Benjamin, D; Jost, JP1
Benz, CC; Kirk, L; Marden, C; Scott, GK; Xu, F1
Adam, E; Bex, F; Bours, V; Burny, A; Carrard, G; Chariot, A; Collette, Y; De Launoit, Y; Friguet, B; Gloire, G; Goffin, V; Nguyên, TL; Piette, J; Quivy, V; Schoonbroodt, S; Van Lint, C; Vanhulle, C1
Barr, NI; Ireland, H; Morrison, V; Munro, J; Parkinson, EK1
Bader, P; Beck, JF; Gänge, J; Kumar, KS; Müller, C; Sonnemann, J1
Aoki, H; Endo, S; Kanzawa, T; Komata, T; Kon, T; Kondo, S; Nashimoto, T; Takahashi, H; Tanaka, R1
Bártová, E; Harnicarová, A; Hofmanová, J; Kovarík, A; Kovaríková, M; Kozubek, M; Kozubek, S; Pacherník, J; Skalníková, M1
Schroeder, TM; Westendorf, JJ1
Ahn, NS; Aruoma, OI; Cho, SD; Hwang, JW; Jo, EH; Jung, JW; Kang, KS; Lee, YS; Park, JS; Yang, SR1
Cheng, C; Han, L; Han, S; Huang, B; Li, L; Lu, J; Zhang, Y1
Ehrenkaufer, GM; Eichinger, DJ; Singh, U1
Cobiac, L; Humphreys, KJ; Le Leu, RK; Michael, MZ; Van der Hoek, MB1
Chand, H; Choi, AM; Contreras, AU; Delgado, M; Hu, CA; Lin, Y; Mebratu, Y; Montano, G; Ryter, SW; Tesfaigzi, Y; Xiang, J1
Fujiki, R; Fujitani, M; Sato, A; Yamashita, T1
Chen, CQ; Chen, CS; Chen, JJ; Gao, SM; Jin, WW; Wu, JB; Xu, HL; Zhou, LP1
Blank, M; Dornelles, AS; Fedi, AC; Pinto, DF; Roesler, R; Schröder, N; Velho, LA; Werenicz, A1
Aronica, E; Creyghton, MP; De Filippis, L; Hol, EM; Kanski, R; Kropff, W; Sluijs, JA; Sneeboer, MA; van Bodegraven, EJ; van Strien, ME; van Tijn, P; Vermunt, MW; Vescovi, A1
Amoêdo, ND; Carvalho, É; Pezzuto, P; Rodrigues, MF; Rumjanek, FD1
Ge, RT; Huang, H; Liu, JQ; Liu, ZG; Mo, LH; Yang, PC; Yu, Y; Zhang, HP; Zheng, PY1
Beck, M; Bork, P; Iskar, M; Mackmull, MT; Ori, A; Parca, L; Singer, S1
Cao, QF; Qian, SB; Shen, HB; Wang, N; Wang, WM; Zhang, L1
Albuquerque, P; Brandão, FA; Derengowski, LS; Nicola, AM; Poças-Fonseca, MJ; Silva-Pereira, I1
Contreras-Leal, E; Flores-Peredo, L; Hernández-Oliveras, A; Santiago-García, J; Zarain-Herzberg, Á1
Blanco, FF; Dixon, DA; Hu, L; Sanduja, S; Sobolewski, C1
Cui, Y; Li, X; Ling, Y; Zhou, J1
Doll, M; Hrgovic, I; Kaufmann, R; Kippenberger, S; Meissner, M; Pinter, A1
Kotantaki, P; Mosialos, G1
Akizuki, R; Endo, S; Hichino, A; Ikari, A; Matsunaga, T; Okamoto, M; Taga, S1
Kim, YH; Lee, JK1
Chen, HX; He, YL; Hu, P; Ke, CZ; Luo, J; Ma, DQ; Meng, ZJ; Ren, P; Wei, ZQ; Zhang, YH1
Li, LX; Li, M; Li, YQ; Long, X; Sun, YY; Zhang, WX; Zhao, DY1
Anantharaju, PG; Chitturi, CMK; Madhunapantula, SV; Padukudru, MA; Reddy, DB; Vimalambike, MG1
Yamato, E1
Becker, L; de Angelis, MH; Klima, C; Nogueira, MS; Peleg, S1
Hernández-Oliveras, A; Izquierdo-Torres, E; Meneses-Morales, I; Rodríguez, G; Santiago-García, J; Zarain-Herzberg, Á1
Brabencová, S; Fajkus, J; Fojtová, M; Ihnatová, I; Kuchaříková, H; Lochmanová, G; Zachová, D; Zdráhal, Z1
Bie, XM; Dong, L; Gao, XQ; Li, XG; Li, XH; Wang, H1
Bocca, AL; Brandão, F; Matos, LF; Morais, JAV; Muehlmann, LA; Poças-Fonseca, MJ; Ranjan, K; Silva-Pereira, I1
Balaban, PM; Zuzina, AB1
Cao, Y; Duan, S; Fu, W; Meng, M; Tang, L; Wang, D; Wang, X; Yang, Y; Zhang, Z1

Reviews

2 review(s) available for butyric acid and trichostatin a

ArticleYear
Chasing a Breath of Fresh Air in Cystic Fibrosis (CF): Therapeutic Potential of Selective HDAC6 Inhibitors to Tackle Multiple Pathways in CF Pathophysiology.
    Journal of medicinal chemistry, 2022, 02-24, Volume: 65, Issue:4

    Topics: Animals; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Histone Deacetylase 6; Humans; Signal Transduction

2022
Histone deacetylase inhibitors interact synergistically with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) to induce apoptosis in carcinoma cell lines.
    Investigational new drugs, 2005, Volume: 23, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Butyric Acid; Caspase 3; Caspases; Cell Line, Tumor; Drug Synergism; Enzyme Inhibitors; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Lung Neoplasms; Male; Membrane Glycoproteins; Prostatic Neoplasms; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha; Vorinostat

2005

Other Studies

66 other study(ies) available for butyric acid and trichostatin a

ArticleYear
Inhibitor scaffolds for 2-oxoglutarate-dependent histone lysine demethylases.
    Journal of medicinal chemistry, 2008, Nov-27, Volume: 51, Issue:22

    Topics: Crystallography, X-Ray; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Ketoglutaric Acids; Models, Molecular; Molecular Structure; Oxidoreductases, N-Demethylating; Protein Structure, Tertiary; Stereoisomerism; Structure-Activity Relationship

2008
Molecular modifications on carboxylic acid derivatives as potent histone deacetylase inhibitors: Activity and docking studies.
    Bioorganic & medicinal chemistry, 2009, Jul-15, Volume: 17, Issue:14

    Topics: Caffeic Acids; Carboxylic Acids; Catalytic Domain; Chlorogenic Acid; Curcumin; Enzyme Inhibitors; HeLa Cells; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Models, Molecular; Molecular Structure; Protein Binding

2009
A Perspective on Medicinal Chemistry Approaches for Targeting Pyruvate Kinase M2.
    Journal of medicinal chemistry, 2022, 01-27, Volume: 65, Issue:2

    Topics: Allosteric Regulation; Allosteric Site; Carrier Proteins; Chemistry, Pharmaceutical; Glycolysis; Humans; Membrane Proteins; Protein Kinase Inhibitors; Thyroid Hormone-Binding Proteins; Thyroid Hormones

2022
Activation of the mouse cytokeratin A (endo A) gene in teratocarcinoma F9 cells by the histone deacetylase inhibitor Trichostatin A.
    FEBS letters, 1994, Oct-17, Volume: 353, Issue:2

    Topics: Animals; Binding Sites; Butyrates; Butyric Acid; Chromatin; Deoxyribonuclease I; DNA; Enhancer Elements, Genetic; Gene Expression; Histone Deacetylase Inhibitors; Hydroxamic Acids; Keratins; Mice; Promoter Regions, Genetic; RNA, Messenger; Teratoma; Tumor Cells, Cultured

1994
Stimulation of tissue-type plasminogen activator gene expression by sodium butyrate and trichostatin A in human endothelial cells involves histone acetylation.
    The Biochemical journal, 1995, Aug-15, Volume: 310 ( Pt 1)

    Topics: Acetylation; Butyrates; Butyric Acid; Cells, Cultured; Endothelium, Vascular; Gene Expression Regulation; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; RNA, Messenger; Tissue Plasminogen Activator; Transcription, Genetic; Tretinoin

1995
Histone acetylation influences both gene expression and development of Xenopus laevis.
    Developmental biology, 1994, Volume: 165, Issue:2

    Topics: Acetylation; Animals; Base Sequence; Butyrates; Butyric Acid; DNA Primers; Gene Expression Regulation, Developmental; Histones; Hydroxamic Acids; Molecular Sequence Data; Morphogenesis; Oocytes; Promoter Regions, Genetic; RNA, Messenger; Transcription, Genetic; Transcriptional Activation; Xenopus laevis

1994
Gene expression within a chromatin domain: the role of core histone hyperacetylation.
    Biochemistry, 1994, Apr-12, Volume: 33, Issue:14

    Topics: Acetylation; Animals; Butyrates; Butyric Acid; Cells, Cultured; Chromatin; Cricetinae; Gene Expression; Histone Deacetylase Inhibitors; Histones; Hydroxamic Acids; Mice; Nucleic Acid Conformation; Promoter Regions, Genetic; Templates, Genetic; Transcription, Genetic

1994
Human fibroblast commitment to a senescence-like state in response to histone deacetylase inhibitors is cell cycle dependent.
    Molecular and cellular biology, 1996, Volume: 16, Issue:9

    Topics: Antigens, Viral, Tumor; Butyrates; Butyric Acid; Cell Cycle; Cell Division; Cell Line; Cellular Senescence; Enzyme Inhibitors; Fibroblasts; HeLa Cells; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Retinoblastoma Protein; Telomere; Transfection

1996
Histone hyperacetylation plays a role in augmentation of IL-4-induced IgE production in LPS-stimulated murine B-lymphocytes by sodium butyrate.
    Journal of biochemistry, 1996, Volume: 119, Issue:6

    Topics: Animals; B-Lymphocytes; Butyrates; Butyric Acid; Histone Deacetylase Inhibitors; Hydroxamic Acids; Immunoglobulin E; In Vitro Techniques; Interleukin-4; Kinetics; Lipopolysaccharides; Mice

1996
Involvement of histone hyperacetylation in triggering DNA fragmentation of rat thymocytes undergoing apoptosis.
    FEBS letters, 1996, Oct-21, Volume: 395, Issue:2-3

    Topics: Acetylation; Acetyltransferases; Animals; Apoptosis; Butyrates; Butyric Acid; Cells, Cultured; DNA; Enzyme Inhibitors; Histone Acetyltransferases; Histones; Hydroxamic Acids; Kinetics; Rats; Rats, Sprague-Dawley; Saccharomyces cerevisiae Proteins; T-Lymphocytes

1996
Inhibition of IL-8 gene expression in Caco-2 cells by compounds which induce histone hyperacetylation.
    Cytokine, 1997, Volume: 9, Issue:1

    Topics: Acetylation; Butyrates; Butyric Acid; Caco-2 Cells; Cell Differentiation; Enzyme Inhibitors; Gene Expression Regulation; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Interleukin-1; Interleukin-8; Phenotype; Propionates; Stimulation, Chemical

1997
Histone acetylation influences thyroid hormone and retinoic acid-mediated gene expression.
    DNA and cell biology, 1997, Volume: 16, Issue:4

    Topics: Acetylation; Animals; Butyrates; Butyric Acid; Cells, Cultured; Enzyme Inhibitors; Gene Expression Regulation; Genes, Reporter; Growth Hormone; Histone Deacetylase Inhibitors; Histones; Hydroxamic Acids; Pituitary Gland; Promoter Regions, Genetic; Rats; Receptors, Retinoic Acid; Receptors, Thyroid Hormone; Transcription, Genetic; Transfection; Tretinoin; Triiodothyronine

1997
Reactivation of silenced, virally transduced genes by inhibitors of histone deacetylase.
    Proceedings of the National Academy of Sciences of the United States of America, 1997, May-27, Volume: 94, Issue:11

    Topics: Animals; Azacitidine; beta-Galactosidase; Butyrates; Butyric Acid; Cloning, Molecular; Cytomegalovirus; Dependovirus; Enzyme Inhibitors; Gene Expression; Genes, Reporter; Genetic Therapy; Genetic Vectors; Globins; HeLa Cells; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Mice; Polymerase Chain Reaction; Recombinant Proteins; Retroviridae; Transfection; Tumor Cells, Cultured

1997
Apoptotic death in adenocarcinoma cell lines induced by butyrate and other histone deacetylase inhibitors.
    Biochemical pharmacology, 1997, May-09, Volume: 53, Issue:9

    Topics: Adenocarcinoma; Apoptosis; Butyrates; Butyric Acid; Colonic Neoplasms; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fatty Acids, Volatile; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1997
Epigenetic silencing of RNA polymerase I transcription: a role for DNA methylation and histone modification in nucleolar dominance.
    Genes & development, 1997, Aug-15, Volume: 11, Issue:16

    Topics: Azacitidine; Brassica; Butyrates; Butyric Acid; Cell Nucleolus; Cytosine; Decitabine; DNA Methylation; Enzyme Inhibitors; Gene Expression Regulation, Plant; Genes, Dominant; Histones; Hydroxamic Acids; Polyploidy; RNA Polymerase I; RNA, Ribosomal; Transcription, Genetic

1997
Induction of caspase-3 protease activity and apoptosis by butyrate and trichostatin A (inhibitors of histone deacetylase): dependence on protein synthesis and synergy with a mitochondrial/cytochrome c-dependent pathway.
    Cancer research, 1997, Sep-01, Volume: 57, Issue:17

    Topics: Apoptosis; bcl-2-Associated X Protein; Butyrates; Butyric Acid; Caspase 3; Caspases; Cells, Cultured; Cycloheximide; Cysteine Endopeptidases; Cytochrome c Group; DNA Fragmentation; DNA, Neoplasm; Enzyme Induction; Histone Deacetylases; Humans; Hydroxamic Acids; Jurkat Cells; Protein Biosynthesis; Protein Kinase Inhibitors; Protein Synthesis Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Staurosporine

1997
Macrophage inflammatory protein-2: chromosomal regulation in rat small intestinal epithelial cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1997, Sep-16, Volume: 94, Issue:19

    Topics: Acetylation; Animals; Butyrates; Butyric Acid; Chemokine CXCL2; Chemotactic Factors; Chromosomes; Culture Techniques; Epithelial Cells; Epithelium; Histones; Hydroxamic Acids; Interleukin-1; Intestine, Small; Lipopolysaccharides; Monokines; Rats; RNA, Messenger

1997
Expression of mutant dynamin inhibits toxicity and transport of endocytosed ricin to the Golgi apparatus.
    The Journal of cell biology, 1998, Feb-09, Volume: 140, Issue:3

    Topics: Biological Transport; Butyrates; Butyric Acid; Cell Division; Dynamins; Endocytosis; Enzyme Inhibitors; Golgi Apparatus; GTP Phosphohydrolases; HeLa Cells; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Lysosomes; Morpholines; Mutation; Protein Biosynthesis; Receptor, IGF Type 2; Ricin; Temperature; Tetracycline

1998
Characterization of a human RPD3 ortholog, HDAC3.
    Proceedings of the National Academy of Sciences of the United States of America, 1998, Mar-17, Volume: 95, Issue:6

    Topics: Amino Acid Sequence; Anti-Bacterial Agents; Base Sequence; Butyrates; Butyric Acid; DNA, Complementary; Gene Expression; Gene Library; Histone Deacetylase 1; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Hydroxamic Acids; Molecular Sequence Data; Nuclear Proteins; Nucleosomes; Peptides; Sequence Homology, Amino Acid; Transcription Factors

1998
Histone deacetylase inhibitors up-regulate the expression of cell surface MHC class-I molecules in B16/BL6 cells.
    The Journal of antibiotics, 1998, Volume: 51, Issue:1

    Topics: Animals; Bacillus megaterium; Butyrates; Butyric Acid; Enzyme Inhibitors; Hemiterpenes; Histocompatibility Antigens Class I; Histone Deacetylase Inhibitors; Hydroxamic Acids; Melanoma, Experimental; Mice; Pentanoic Acids; Up-Regulation

1998
Histone acetylation is required to maintain the unfolded nucleosome structure associated with transcribing DNA.
    The Journal of biological chemistry, 1998, Jun-05, Volume: 273, Issue:23

    Topics: Acetylation; Animals; Butyrates; Butyric Acid; Chickens; Chromatin; Chromatography, Affinity; Cysteine; Erythrocytes; Histone Deacetylase Inhibitors; Histones; Hydroxamic Acids; Nucleosomes; Sulfhydryl Reagents; Transcription, Genetic

1998
Differential expression of human histone deacetylase mRNAs in response to immune cell apoptosis induction by trichostatin A and butyrate.
    Biochemical and biophysical research communications, 1998, Jun-29, Volume: 247, Issue:3

    Topics: Acetyltransferases; Apoptosis; Butyrates; Butyric Acid; CD4-Positive T-Lymphocytes; Cell Cycle; Cell Division; Down-Regulation; Flow Cytometry; Gene Expression Regulation; Genes, p53; Histone Acetyltransferases; Histone Deacetylases; Humans; Hydroxamic Acids; Interferon-gamma; Isoenzymes; Phytohemagglutinins; RNA, Messenger; Saccharomyces cerevisiae Proteins; Thymidine; Up-Regulation

1998
Quantitative PCR analysis of HbF inducers in primary human adult erythroid cells.
    Blood, 2000, Feb-01, Volume: 95, Issue:3

    Topics: Adult; Azacitidine; Butyric Acid; DNA, Complementary; Erythroid Precursor Cells; Erythropoietin; Fetal Hemoglobin; Gene Expression Regulation; Globins; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Hydroxyurea; Polymerase Chain Reaction; RNA, Messenger

2000
Sp1 and chromatin environment are important contributors to the formation of repressive chromatin structures on the transfected human adenine nucleotide translocase-2 promoter.
    The Biochemical journal, 2000, Feb-15, Volume: 346 Pt 1

    Topics: 3T3 Cells; Acetylation; Animals; Butyric Acid; Chromatin; Gene Silencing; Genes, Reporter; Genome; HeLa Cells; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Mice; Mitochondrial ADP, ATP Translocases; Molecular Conformation; Mutation; Promoter Regions, Genetic; Recombination, Genetic; Response Elements; Sp1 Transcription Factor; Transcriptional Activation; Transfection

2000
Mechanism for inactivation of the KIP family cyclin-dependent kinase inhibitor genes in gastric cancer cells.
    Cancer research, 2000, Jan-15, Volume: 60, Issue:2

    Topics: Azacitidine; Butyric Acid; CDC2 Protein Kinase; Cell Cycle Proteins; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinase Inhibitor p57; Decitabine; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Microtubule-Associated Proteins; Nuclear Proteins; Restriction Mapping; Reverse Transcriptase Polymerase Chain Reaction; Stomach Neoplasms; Transcription, Genetic; Tumor Cells, Cultured; Tumor Suppressor Proteins

2000
Modulation of complement component (C3 and factor B) biosynthesis by a histone deacetylase inhibitor in human intestinal epithelial cells.
    International journal of molecular medicine, 2000, Volume: 6, Issue:1

    Topics: Blotting, Northern; Butyric Acid; CCAAT-Enhancer-Binding Proteins; Complement C3; Complement Factor B; DNA-Binding Proteins; Enzyme Inhibitors; Epithelial Cells; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Intestinal Mucosa; NF-kappa B; Nuclear Proteins; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

2000
Synergistic growth inhibition of prostate cancer cells by 1 alpha,25 Dihydroxyvitamin D(3) and its 19-nor-hexafluoride analogs in combination with either sodium butyrate or trichostatin A.
    Oncogene, 2001, Apr-05, Volume: 20, Issue:15

    Topics: Antineoplastic Agents; Apoptosis; Butyric Acid; Calcitriol; Cell Cycle; Cholecalciferol; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cytochrome P-450 Enzyme System; Drug Synergism; Enzyme Inhibitors; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Male; Prostatic Neoplasms; Steroid Hydroxylases; Transcriptional Activation; Tumor Cells, Cultured; Vitamin D3 24-Hydroxylase

2001
Reversal of methylation-mediated repression with short-chain fatty acids: evidence for an additional mechanism to histone deacetylation.
    Nucleic acids research, 2001, Sep-01, Volume: 29, Issue:17

    Topics: Animals; beta-Galactosidase; Butyric Acid; Caproates; Cell Line; Chromatin; DNA; DNA Footprinting; DNA Methylation; Drug Synergism; Ecdysterone; Fatty Acids, Volatile; Gene Expression Regulation; Gene Silencing; Histone Deacetylases; Histones; Humans; Hydroxamic Acids; Kinetics; Lac Operon; Plasmids; Promoter Regions, Genetic; Time Factors

2001
Transcriptional repression of ErbB2 by histone deacetylase inhibitors detected by a genomically integrated ErbB2 promoter-reporting cell screen.
    Molecular cancer therapeutics, 2002, Volume: 1, Issue:6

    Topics: Blotting, Western; Breast Neoplasms; Butyric Acid; Cell Survival; Deoxyribonuclease I; DNA Probes; Down-Regulation; Drug Resistance, Neoplasm; Enzyme Inhibitors; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Luciferases; Nucleotide Mapping; Promoter Regions, Genetic; Receptor, ErbB-2; Response Elements; Transcription, Genetic; Transfection; Tumor Cells, Cultured

2002
Potentiation of tumor necrosis factor-induced NF-kappa B activation by deacetylase inhibitors is associated with a delayed cytoplasmic reappearance of I kappa B alpha.
    Molecular and cellular biology, 2003, Volume: 23, Issue:17

    Topics: Animals; Butyric Acid; Cysteine Endopeptidases; Cytoplasm; Enzyme Inhibitors; HeLa Cells; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; I-kappa B Kinase; I-kappa B Proteins; Leupeptins; Mitogen-Activated Protein Kinases; Multienzyme Complexes; NF-kappa B; NF-KappaB Inhibitor alpha; Proteasome Endopeptidase Complex; Protein Serine-Threonine Kinases; Protein Transport; Transcription Factor RelA; Tumor Necrosis Factor-alpha

2003
Histone deacetylase inhibitors induce a senescence-like state in human cells by a p16-dependent mechanism that is independent of a mitotic clock.
    Experimental cell research, 2004, May-01, Volume: 295, Issue:2

    Topics: Animals; Butyric Acid; Cell Division; Cell Line; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p16; Diploidy; Enzyme Inhibitors; Fetus; Fibroblasts; Gene Expression Regulation; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Karyotyping; Mice; Papillomaviridae; Precipitin Tests; Retinoblastoma Protein; Signal Transduction; Skin; Species Specificity; Tumor Suppressor Protein p53; Up-Regulation

2004
Histone deacetylase inhibitors, N-butyric acid and trichostatin A, induce caspase-8- but not caspase-9-dependent apoptosis in human malignant glioma cells.
    International journal of oncology, 2005, Volume: 26, Issue:5

    Topics: Apoptosis; Brain Neoplasms; Butyric Acid; Caspase 8; Caspase 9; Caspases; Cell Cycle; Cell Cycle Proteins; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Enzyme Induction; Enzyme Inhibitors; Glioma; Histamine Antagonists; Humans; Hydroxamic Acids

2005
Nuclear levels and patterns of histone H3 modification and HP1 proteins after inhibition of histone deacetylases.
    Journal of cell science, 2005, Nov-01, Volume: 118, Issue:Pt 21

    Topics: Apoptosis; Butyric Acid; Carcinoma, Small Cell; Cell Cycle; Cell Line; Cell Line, Tumor; Cell Nucleus; Chromatin; Chromobox Protein Homolog 5; Chromosomal Proteins, Non-Histone; Colonic Neoplasms; Enzyme Inhibitors; Fetus; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; HT29 Cells; Humans; Hydroxamic Acids; Interphase; Lung Neoplasms

2005
Histone deacetylase inhibitors promote osteoblast maturation.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2005, Volume: 20, Issue:12

    Topics: Acetylation; Alkaline Phosphatase; Animals; Benzamides; Butyric Acid; Calcification, Physiologic; Calcium; Cell Cycle; Cell Differentiation; Cell Line; Cell Shape; Cell Survival; Cells, Cultured; Collagen Type I; Core Binding Factor Alpha 1 Subunit; Enzyme Inhibitors; Gene Expression; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Hydroxamic Acids; Integrin-Binding Sialoprotein; Mice; Organ Culture Techniques; Osteoblasts; Osteocalcin; Osteopontin; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; Sialoglycoproteins; Skull; Valproic Acid

2005
Effects of the histone deacetylases inhibitors sodium butyrate and trichostatin A on the inhibition of gap junctional intercellular communication by H2O2- and 12-O-tetradecanoylphorbol-13-acetate in rat liver epithelial cells.
    Cancer letters, 2006, Sep-28, Volume: 241, Issue:2

    Topics: Animals; Butyric Acid; Carcinogens; Cell Communication; Cells, Cultured; Enzyme Inhibitors; Epithelial Cells; Gap Junctions; Histamine Antagonists; Histone Deacetylase Inhibitors; Hydrogen Peroxide; Hydroxamic Acids; Liver; Mitogen-Activated Protein Kinases; Oxidants; Phosphorylation; Rats; Tetradecanoylphorbol Acetate

2006
HDAC inhibitors TSA and sodium butyrate enhanced the human IL-5 expression by altering histone acetylation status at its promoter region.
    Immunology letters, 2007, Feb-15, Volume: 108, Issue:2

    Topics: Acetylation; Butyric Acid; Cell Line; Chromatin Immunoprecipitation; Enzyme Inhibitors; Gene Expression; Genes, Reporter; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Interleukin-5; Ionomycin; Jurkat Cells; Mutagenesis, Site-Directed; Promoter Regions, Genetic; Response Elements; Tetradecanoylphorbol Acetate; Transfection

2007
Trichostatin A effects on gene expression in the protozoan parasite Entamoeba histolytica.
    BMC genomics, 2007, Jul-05, Volume: 8

    Topics: Animals; Butyric Acid; Entamoeba histolytica; Gene Expression Profiling; Gene Expression Regulation; Genes, Protozoan; Histones; Hydroxamic Acids; Oligonucleotide Array Sequence Analysis; Propionates; Reverse Transcriptase Polymerase Chain Reaction; Sodium Acetate

2007
Histone deacetylase inhibition in colorectal cancer cells reveals competing roles for members of the oncogenic miR-17-92 cluster.
    Molecular carcinogenesis, 2013, Volume: 52, Issue:6

    Topics: Adaptor Proteins, Signal Transducing; Adenocarcinoma; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Butyric Acid; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Down-Regulation; Gene Expression Regulation, Neoplastic; HCT116 Cells; Histone Deacetylase Inhibitors; HT29 Cells; Humans; Hydroxamic Acids; Membrane Proteins; MicroRNAs; Phosphoproteins; Proto-Oncogene Proteins; PTEN Phosphohydrolase; RNA, Long Noncoding; RNA, Messenger; Transfection; Vorinostat

2013
Deacetylation of p53 induces autophagy by suppressing Bmf expression.
    The Journal of cell biology, 2013, Apr-29, Volume: 201, Issue:3

    Topics: Acetylation; Adaptor Proteins, Signal Transducing; Animals; Autophagy; Butyric Acid; Cell Nucleus; Cells, Cultured; Epithelial Cells; Gene Expression; Gene Silencing; Histone Deacetylase 1; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Interferon-gamma; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Promoter Regions, Genetic; Protein Processing, Post-Translational; Respiratory Mucosa; Tumor Suppressor Protein p53

2013
A proapoptotic effect of valproic acid on progenitors of embryonic stem cell-derived glutamatergic neurons.
    Cell death & disease, 2013, Jun-20, Volume: 4

    Topics: Acetylation; Animals; Anticonvulsants; Apoptosis; Butyric Acid; Cell Line; Cells, Cultured; Embryonic Stem Cells; Histone Deacetylase Inhibitors; Histones; Hydroxamic Acids; Mice; Neural Stem Cells; Neurons; Protein Processing, Post-Translational; Valproic Acid

2013
Histone deacetylases inhibitor trichostatin A increases the expression of Dleu2/miR-15a/16-1 via HDAC3 in non-small cell lung cancer.
    Molecular and cellular biochemistry, 2013, Volume: 383, Issue:1-2

    Topics: Acetylation; Apoptosis; Butyric Acid; Carcinoma, Non-Small-Cell Lung; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Hydroxamic Acids; Lung Neoplasms; MicroRNAs; Promoter Regions, Genetic; Proto-Oncogene Proteins c-bcl-2; RNA, Long Noncoding; Transferases; Tumor Stem Cell Assay; Tumor Suppressor Proteins; Up-Regulation

2013
Basolateral amygdala activity is required for enhancement of memory consolidation produced by histone deacetylase inhibition in the hippocampus.
    Neurobiology of learning and memory, 2014, Volume: 111

    Topics: Animals; Basolateral Nuclear Complex; Butyric Acid; Hippocampus; Histone Deacetylase Inhibitors; Hydroxamic Acids; Male; Memory; Rats, Wistar

2014
Histone acetylation in astrocytes suppresses GFAP and stimulates a reorganization of the intermediate filament network.
    Journal of cell science, 2014, Oct-15, Volume: 127, Issue:Pt 20

    Topics: Acetylation; Alexander Disease; Alternative Splicing; Astrocytes; Butyric Acid; Cell Line, Tumor; Cytoskeleton; Epigenesis, Genetic; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Hydroxamic Acids; Protein Aggregates; Protein Isoforms; Protein Multimerization

2014
Reciprocal modulation of histone deacetylase inhibitors sodium butyrate and trichostatin A on the energy metabolism of breast cancer cells.
    Journal of cellular biochemistry, 2015, Volume: 116, Issue:5

    Topics: Breast Neoplasms; Butyric Acid; Cell Line, Tumor; Energy Metabolism; Glycolysis; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Metabolic Networks and Pathways; Oxidation-Reduction

2015
Regulation of TWIK-related potassium channel-1 (Trek1) restitutes intestinal epithelial barrier function.
    Cellular & molecular immunology, 2016, Volume: 13, Issue:1

    Topics: Animals; Butyric Acid; Cell Line; Clostridium butyricum; Cytokines; Eosinophils; Epithelial Cells; Gene Expression Regulation; Histone Deacetylase 1; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Hypersensitivity; Intestinal Mucosa; Mast Cells; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; Ovalbumin; Potassium Channels, Tandem Pore Domain; Probiotics; Signal Transduction

2016
Histone Deacetylase Inhibitors (HDACi) Cause the Selective Depletion of Bromodomain Containing Proteins (BCPs).
    Molecular & cellular proteomics : MCP, 2015, Volume: 14, Issue:5

    Topics: Acetylation; Butyric Acid; Carrier Proteins; Cell Cycle Proteins; Co-Repressor Proteins; CREB-Binding Protein; DNA-Binding Proteins; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Silencing; HeLa Cells; Histone Acetyltransferases; Histone Chaperones; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Hydroxamic Acids; Nuclear Proteins; Protein Processing, Post-Translational; RNA, Small Interfering; Transcription Factors; Transcription, Genetic; Vorinostat

2015
TRPM2 mediates histone deacetylase inhibition-induced apoptosis in bladder cancer cells.
    Cancer biotherapy & radiopharmaceuticals, 2015, Volume: 30, Issue:2

    Topics: Apoptosis; Butyric Acid; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Promoter Regions, Genetic; TRPM Cation Channels; Up-Regulation; Urinary Bladder Neoplasms

2015
Histone deacetylases inhibitors effects on Cryptococcus neoformans major virulence phenotypes.
    Virulence, 2015, Volume: 6, Issue:6

    Topics: Animals; Butyric Acid; Cell Division; Cryptococcus neoformans; Disease Models, Animal; Fungal Capsules; Histone Deacetylase Inhibitors; Hydroxamic Acids; Lepidoptera; Melanins; Microbial Viability; Phenotype; Phospholipases; Survival Analysis; Temperature; Virulence

2015
Histone deacetylase inhibitors promote the expression of ATP2A3 gene in breast cancer cell lines.
    Molecular carcinogenesis, 2016, Volume: 55, Issue:10

    Topics: Breast Neoplasms; Butyric Acid; Cell Line, Tumor; CpG Islands; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; MCF-7 Cells; Promoter Regions, Genetic; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Up-Regulation

2016
Histone Deacetylase Inhibitors Activate Tristetraprolin Expression through Induction of Early Growth Response Protein 1 (EGR1) in Colorectal Cancer Cells.
    Biomolecules, 2015, Aug-28, Volume: 5, Issue:3

    Topics: Butyric Acid; Cell Line, Tumor; Colorectal Neoplasms; Cyclooxygenase 2; Early Growth Response Protein 1; Epigenesis, Genetic; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; RNA, Messenger; Tristetraprolin; Vorinostat

2015
Interference of the Histone Deacetylase Inhibits Pollen Germination and Pollen Tube Growth in Picea wilsonii Mast.
    PloS one, 2015, Volume: 10, Issue:12

    Topics: Actin Cytoskeleton; Butyric Acid; Calcium; Cell Wall; Germination; Glucans; Histone Deacetylase Inhibitors; Histone Deacetylases; Hydroxamic Acids; Pectins; Picea; Pollen; Pollen Tube

2015
Histone deacetylase inhibitors interfere with angiogenesis by decreasing endothelial VEGFR-2 protein half-life in part via a VE-cadherin-dependent mechanism.
    Experimental dermatology, 2017, Volume: 26, Issue:2

    Topics: Antigens, CD; Butyric Acid; Cadherins; Endothelium; Gene Expression; Gene Knockdown Techniques; Half-Life; Histone Deacetylase 1; Histone Deacetylase 6; Histone Deacetylase Inhibitors; Histone Deacetylases; Human Umbilical Vein Endothelial Cells; Humans; Hydroxamic Acids; Neovascularization, Physiologic; Repressor Proteins; RNA, Messenger; RNA, Small Interfering; Valproic Acid; Vascular Endothelial Growth Factor Receptor-2

2017
The expression of tumor suppressor gene Cyld is upregulated by histone deacetylace inhibitors in human hepatocellular carcinoma cell lines.
    Cell biochemistry and function, 2016, Volume: 34, Issue:7

    Topics: Butyric Acid; Carcinoma, Hepatocellular; Cell Line, Tumor; Deubiquitinating Enzyme CYLD; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Liver Neoplasms; Tumor Suppressor Proteins; Up-Regulation; Vorinostat

2016
Down-regulation of Claudin-2 Expression and Proliferation by Epigenetic Inhibitors in Human Lung Adenocarcinoma A549 Cells.
    The Journal of biological chemistry, 2017, 02-10, Volume: 292, Issue:6

    Topics: A549 Cells; Adenocarcinoma; Adenocarcinoma of Lung; Azacitidine; Butyric Acid; Cell Proliferation; Chromones; Claudin-2; Down-Regulation; Epigenesis, Genetic; Humans; Hydroxamic Acids; Lung Neoplasms; MicroRNAs; Morpholines; Nitriles; RNA, Messenger; Signal Transduction; Sulfones

2017
Histone deacetylase inhibitors suppress immature dendritic cell's migration by regulating CC chemokine receptor 1 expression.
    Cellular immunology, 2017, Volume: 316

    Topics: Animals; Butyric Acid; Cell Differentiation; Cell Movement; Cells, Cultured; Chemokine CCL3; Dendritic Cells; Down-Regulation; Histone Deacetylase Inhibitors; Hydroxamic Acids; Hydroxylamines; Mice; Mice, Inbred C57BL; Quinolines; Receptors, CCR1

2017
Curcumin inhibits hepatitis B virus infection by down-regulating cccDNA-bound histone acetylation.
    World journal of gastroenterology, 2017, Sep-14, Volume: 23, Issue:34

    Topics: Acetylation; Antiviral Agents; Butyric Acid; Chromatin Immunoprecipitation; Curcumin; DNA Replication; DNA, Circular; DNA, Viral; Dose-Response Relationship, Drug; Down-Regulation; Drug Synergism; E1A-Associated p300 Protein; Hep G2 Cells; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Real-Time Polymerase Chain Reaction; RNA Interference; RNA, Small Interfering

2017
Butyrate promotes visceral hypersensitivity in an IBS-like model via enteric glial cell-derived nerve growth factor.
    Neurogastroenterology and motility, 2018, Volume: 30, Issue:4

    Topics: Animals; Butyric Acid; Cell Line; Disease Models, Animal; Enteric Nervous System; Gene Expression Profiling; Histone Deacetylase Inhibitors; Hydroxamic Acids; Irritable Bowel Syndrome; Male; Nerve Growth Factor; Neuroglia; Rats, Sprague-Dawley; Transcriptome; Visceral Pain

2018
Induction of colon and cervical cancer cell death by cinnamic acid derivatives is mediated through the inhibition of Histone Deacetylases (HDAC).
    PloS one, 2017, Volume: 12, Issue:11

    Topics: Apoptosis; Binding Sites; Butyric Acid; Cell Line, Tumor; Cinnamates; Colorectal Neoplasms; Female; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Uterine Cervical Neoplasms

2017
High dose of histone deacetylase inhibitors affects insulin secretory mechanism of pancreatic beta cell line.
    Endocrine regulations, 2018, Jan-01, Volume: 52, Issue:1

    Topics: Animals; Butyric Acid; Cattle; Cell Line; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Insulin; Insulin-Secreting Cells; Valproic Acid

2018
Rapid and transient oxygen consumption increase following acute HDAC/KDAC inhibition in Drosophila tissue.
    Scientific reports, 2018, 03-08, Volume: 8, Issue:1

    Topics: Acetylation; Animals; Butyric Acid; Drosophila melanogaster; Drosophila Proteins; Female; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Hydroxamic Acids; Male; Oxygen Consumption

2018
Histone deacetylase inhibitors promote ATP2A3 gene expression in hepatocellular carcinoma cells: p300 as a transcriptional regulator.
    The international journal of biochemistry & cell biology, 2019, Volume: 113

    Topics: Animals; Butyric Acid; Carcinoma, Hepatocellular; E1A-Associated p300 Protein; Gene Expression; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Liver Neoplasms; Promoter Regions, Genetic; Rats; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Tumor Cells, Cultured

2019
Different Modes of Action of Genetic and Chemical Downregulation of Histone Deacetylases with Respect to Plant Development and Histone Modifications.
    International journal of molecular sciences, 2019, Oct-14, Volume: 20, Issue:20

    Topics: Arabidopsis; Arabidopsis Proteins; Butyric Acid; DNA Methylation; Gene Expression Regulation, Plant; Gene Silencing; Germination; Histone Code; Histone Deacetylase Inhibitors; Histone Deacetylases; Hydroxamic Acids; Plant Development; Proteomics; Seedlings

2019
Trichostatin A and sodium butyrate promotes plant regeneration in common wheat.
    Plant signaling & behavior, 2020, 12-01, Volume: 15, Issue:12

    Topics: Butyric Acid; Cell Differentiation; Hydroxamic Acids; Regeneration; Triticum

2020
The role of Cryptococcus neoformans histone deacetylase genes in the response to antifungal drugs, epigenetic modulators and to photodynamic therapy mediated by an aluminium phthalocyanine chloride nanoemulsion in vitro.
    Journal of photochemistry and photobiology. B, Biology, 2021, Volume: 216

    Topics: Amphotericin B; Antifungal Agents; Bacterial Proteins; Butyric Acid; Cryptococcosis; Cryptococcus neoformans; Drug Synergism; Emulsions; Epigenesis, Genetic; Fluconazole; Gene Expression Regulation, Bacterial; Histone Deacetylases; Humans; Hydroxamic Acids; Indoles; Nanoparticles; Organometallic Compounds; Photochemotherapy; Sulfamethoxazole

2021
Contribution of histone acetylation to the serotonin-mediated long-term synaptic plasticity in terrestrial snails.
    Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology, 2022, Volume: 208, Issue:5-6

    Topics: Animals; Butyric Acid; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Neuronal Plasticity; Serotonin

2022
Histone deacetylase inhibitors inhibit lung adenocarcinoma metastasis via HDAC2/YY1 mediated downregulation of Cdh1.
    Scientific reports, 2023, 07-26, Volume: 13, Issue:1

    Topics: Adenocarcinoma of Lung; Animals; Antigens, CD; Butyric Acid; Cadherins; Cell Movement; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Histone Deacetylase 2; Histone Deacetylase Inhibitors; Humans; Mice; Neoplasm Metastasis; Protein Binding; Transcription, Genetic; Transforming Growth Factor beta; YY1 Transcription Factor

2023