butyric acid has been researched along with trichostatin a in 68 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 19 (27.94) | 18.2507 |
2000's | 18 (26.47) | 29.6817 |
2010's | 25 (36.76) | 24.3611 |
2020's | 6 (8.82) | 2.80 |
Authors | Studies |
---|---|
Bello, SH; Liénard, BM; McDonough, MA; Mecinović, J; Ng, SS; Oppermann, U; Rose, NR; Schofield, CJ; Sun, Z | 1 |
Bora-Tatar, G; Dalkara, S; Dayangaç-Erden, D; Demir, AS; Erdem-Yurter, H; Yelekçi, K | 1 |
Arora, S; Chaturvedi, A; Heuser, M; Joshi, G; Kumar, R; Patil, S | 1 |
Alfano, AI; Barone, S; Brindisi, M; Cassese, E; Summa, V | 1 |
Matsushiro, A; Miyashita, T; Morita, T; Nishimune, Y; Nozaki, M; Yamamoto, H | 1 |
Arts, J; Grimbergen, J; Kooistra, T; Lansink, M; Toet, KH | 1 |
Almouzni, G; Dimitrov, S; Khochbin, S; Wolffe, AP | 1 |
Beppu, T; Bode, J; Klehr-Wirth, D; Schlake, T; Yoshida, M | 1 |
Barbie, DA; Hirai, TH; Howard, BH; Ogryzko, VV; Russanova, VR | 1 |
Doi, S; Hanmyou, F; Matsunaga, T; Nakamura, Y; Sakata, K; Yamamoto, I | 1 |
Furukubo, T; Kariya, K; Lee, E; Miyabe, T; Yamauchi, A | 1 |
Huang, N; Katz, JP; Martin, DR; Wu, GD | 1 |
Aranda, A; Castillo, AI; Garcia-Villalba, P; Jimenez-Lara, AM | 1 |
Bailey, EC; Chen, WY; Dong, JY; McCune, SL; Townes, TM | 1 |
Eastman, A; McBain, JA; Mueller, GC; Nobel, CS | 1 |
Chen, ZJ; Pikaard, CS | 1 |
Appleton, S; Edmonds, B; James, R; Medina, V; Young, GP; Zalewski, PD | 1 |
Fusunyan, RD; Lee, J; MacDermott, RP; Ohno, Y; Sanderson, IR | 1 |
Llorente, A; Rapak, A; Sandvig, K; Schmid, SL; van Deurs, B | 1 |
Al-Abed, Y; Emiliani, S; Fischle, W; Van Lint, C; Verdin, E | 1 |
Hayashi, H; Komatsu, Y | 1 |
Chen, HY; Davie, JR; Holth, LT; Sun, JM; Walia, H | 1 |
Dangond, F; Gullans, SR | 1 |
Li, J; Noguchi, CT; Schechter, AN; Smith, RD | 1 |
Barath, P; Hodny, Z; Li, R; Nelson, BD | 1 |
Kim, HS; Lee, JY; Park, J; Park, JB; Shin, JY | 1 |
Andoh, A; Bamba, T; Fujiyama, Y; Shimada, M | 1 |
Brown, G; Campbell, MJ; Driver, PM; Edwards, CE; Engel, J; Moore, JS; Rashid, SF; Uskokovic, MR; Walker, E | 1 |
Benjamin, D; Jost, JP | 1 |
Benz, CC; Kirk, L; Marden, C; Scott, GK; Xu, F | 1 |
Adam, E; Bex, F; Bours, V; Burny, A; Carrard, G; Chariot, A; Collette, Y; De Launoit, Y; Friguet, B; Gloire, G; Goffin, V; Nguyên, TL; Piette, J; Quivy, V; Schoonbroodt, S; Van Lint, C; Vanhulle, C | 1 |
Barr, NI; Ireland, H; Morrison, V; Munro, J; Parkinson, EK | 1 |
Bader, P; Beck, JF; Gänge, J; Kumar, KS; Müller, C; Sonnemann, J | 1 |
Aoki, H; Endo, S; Kanzawa, T; Komata, T; Kon, T; Kondo, S; Nashimoto, T; Takahashi, H; Tanaka, R | 1 |
Bártová, E; Harnicarová, A; Hofmanová, J; Kovarík, A; Kovaríková, M; Kozubek, M; Kozubek, S; Pacherník, J; Skalníková, M | 1 |
Schroeder, TM; Westendorf, JJ | 1 |
Ahn, NS; Aruoma, OI; Cho, SD; Hwang, JW; Jo, EH; Jung, JW; Kang, KS; Lee, YS; Park, JS; Yang, SR | 1 |
Cheng, C; Han, L; Han, S; Huang, B; Li, L; Lu, J; Zhang, Y | 1 |
Ehrenkaufer, GM; Eichinger, DJ; Singh, U | 1 |
Cobiac, L; Humphreys, KJ; Le Leu, RK; Michael, MZ; Van der Hoek, MB | 1 |
Chand, H; Choi, AM; Contreras, AU; Delgado, M; Hu, CA; Lin, Y; Mebratu, Y; Montano, G; Ryter, SW; Tesfaigzi, Y; Xiang, J | 1 |
Fujiki, R; Fujitani, M; Sato, A; Yamashita, T | 1 |
Chen, CQ; Chen, CS; Chen, JJ; Gao, SM; Jin, WW; Wu, JB; Xu, HL; Zhou, LP | 1 |
Blank, M; Dornelles, AS; Fedi, AC; Pinto, DF; Roesler, R; Schröder, N; Velho, LA; Werenicz, A | 1 |
Aronica, E; Creyghton, MP; De Filippis, L; Hol, EM; Kanski, R; Kropff, W; Sluijs, JA; Sneeboer, MA; van Bodegraven, EJ; van Strien, ME; van Tijn, P; Vermunt, MW; Vescovi, A | 1 |
Amoêdo, ND; Carvalho, É; Pezzuto, P; Rodrigues, MF; Rumjanek, FD | 1 |
Ge, RT; Huang, H; Liu, JQ; Liu, ZG; Mo, LH; Yang, PC; Yu, Y; Zhang, HP; Zheng, PY | 1 |
Beck, M; Bork, P; Iskar, M; Mackmull, MT; Ori, A; Parca, L; Singer, S | 1 |
Cao, QF; Qian, SB; Shen, HB; Wang, N; Wang, WM; Zhang, L | 1 |
Albuquerque, P; Brandão, FA; Derengowski, LS; Nicola, AM; Poças-Fonseca, MJ; Silva-Pereira, I | 1 |
Contreras-Leal, E; Flores-Peredo, L; Hernández-Oliveras, A; Santiago-García, J; Zarain-Herzberg, Á | 1 |
Blanco, FF; Dixon, DA; Hu, L; Sanduja, S; Sobolewski, C | 1 |
Cui, Y; Li, X; Ling, Y; Zhou, J | 1 |
Doll, M; Hrgovic, I; Kaufmann, R; Kippenberger, S; Meissner, M; Pinter, A | 1 |
Kotantaki, P; Mosialos, G | 1 |
Akizuki, R; Endo, S; Hichino, A; Ikari, A; Matsunaga, T; Okamoto, M; Taga, S | 1 |
Kim, YH; Lee, JK | 1 |
Chen, HX; He, YL; Hu, P; Ke, CZ; Luo, J; Ma, DQ; Meng, ZJ; Ren, P; Wei, ZQ; Zhang, YH | 1 |
Li, LX; Li, M; Li, YQ; Long, X; Sun, YY; Zhang, WX; Zhao, DY | 1 |
Anantharaju, PG; Chitturi, CMK; Madhunapantula, SV; Padukudru, MA; Reddy, DB; Vimalambike, MG | 1 |
Yamato, E | 1 |
Becker, L; de Angelis, MH; Klima, C; Nogueira, MS; Peleg, S | 1 |
Hernández-Oliveras, A; Izquierdo-Torres, E; Meneses-Morales, I; Rodríguez, G; Santiago-García, J; Zarain-Herzberg, Á | 1 |
Brabencová, S; Fajkus, J; Fojtová, M; Ihnatová, I; Kuchaříková, H; Lochmanová, G; Zachová, D; Zdráhal, Z | 1 |
Bie, XM; Dong, L; Gao, XQ; Li, XG; Li, XH; Wang, H | 1 |
Bocca, AL; Brandão, F; Matos, LF; Morais, JAV; Muehlmann, LA; Poças-Fonseca, MJ; Ranjan, K; Silva-Pereira, I | 1 |
Balaban, PM; Zuzina, AB | 1 |
Cao, Y; Duan, S; Fu, W; Meng, M; Tang, L; Wang, D; Wang, X; Yang, Y; Zhang, Z | 1 |
2 review(s) available for butyric acid and trichostatin a
Article | Year |
---|---|
Chasing a Breath of Fresh Air in Cystic Fibrosis (CF): Therapeutic Potential of Selective HDAC6 Inhibitors to Tackle Multiple Pathways in CF Pathophysiology.
Topics: Animals; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Histone Deacetylase 6; Humans; Signal Transduction | 2022 |
Histone deacetylase inhibitors interact synergistically with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) to induce apoptosis in carcinoma cell lines.
Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Butyric Acid; Caspase 3; Caspases; Cell Line, Tumor; Drug Synergism; Enzyme Inhibitors; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Lung Neoplasms; Male; Membrane Glycoproteins; Prostatic Neoplasms; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha; Vorinostat | 2005 |
66 other study(ies) available for butyric acid and trichostatin a
Article | Year |
---|---|
Inhibitor scaffolds for 2-oxoglutarate-dependent histone lysine demethylases.
Topics: Crystallography, X-Ray; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Ketoglutaric Acids; Models, Molecular; Molecular Structure; Oxidoreductases, N-Demethylating; Protein Structure, Tertiary; Stereoisomerism; Structure-Activity Relationship | 2008 |
Molecular modifications on carboxylic acid derivatives as potent histone deacetylase inhibitors: Activity and docking studies.
Topics: Caffeic Acids; Carboxylic Acids; Catalytic Domain; Chlorogenic Acid; Curcumin; Enzyme Inhibitors; HeLa Cells; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Models, Molecular; Molecular Structure; Protein Binding | 2009 |
A Perspective on Medicinal Chemistry Approaches for Targeting Pyruvate Kinase M2.
Topics: Allosteric Regulation; Allosteric Site; Carrier Proteins; Chemistry, Pharmaceutical; Glycolysis; Humans; Membrane Proteins; Protein Kinase Inhibitors; Thyroid Hormone-Binding Proteins; Thyroid Hormones | 2022 |
Activation of the mouse cytokeratin A (endo A) gene in teratocarcinoma F9 cells by the histone deacetylase inhibitor Trichostatin A.
Topics: Animals; Binding Sites; Butyrates; Butyric Acid; Chromatin; Deoxyribonuclease I; DNA; Enhancer Elements, Genetic; Gene Expression; Histone Deacetylase Inhibitors; Hydroxamic Acids; Keratins; Mice; Promoter Regions, Genetic; RNA, Messenger; Teratoma; Tumor Cells, Cultured | 1994 |
Stimulation of tissue-type plasminogen activator gene expression by sodium butyrate and trichostatin A in human endothelial cells involves histone acetylation.
Topics: Acetylation; Butyrates; Butyric Acid; Cells, Cultured; Endothelium, Vascular; Gene Expression Regulation; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; RNA, Messenger; Tissue Plasminogen Activator; Transcription, Genetic; Tretinoin | 1995 |
Histone acetylation influences both gene expression and development of Xenopus laevis.
Topics: Acetylation; Animals; Base Sequence; Butyrates; Butyric Acid; DNA Primers; Gene Expression Regulation, Developmental; Histones; Hydroxamic Acids; Molecular Sequence Data; Morphogenesis; Oocytes; Promoter Regions, Genetic; RNA, Messenger; Transcription, Genetic; Transcriptional Activation; Xenopus laevis | 1994 |
Gene expression within a chromatin domain: the role of core histone hyperacetylation.
Topics: Acetylation; Animals; Butyrates; Butyric Acid; Cells, Cultured; Chromatin; Cricetinae; Gene Expression; Histone Deacetylase Inhibitors; Histones; Hydroxamic Acids; Mice; Nucleic Acid Conformation; Promoter Regions, Genetic; Templates, Genetic; Transcription, Genetic | 1994 |
Human fibroblast commitment to a senescence-like state in response to histone deacetylase inhibitors is cell cycle dependent.
Topics: Antigens, Viral, Tumor; Butyrates; Butyric Acid; Cell Cycle; Cell Division; Cell Line; Cellular Senescence; Enzyme Inhibitors; Fibroblasts; HeLa Cells; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Retinoblastoma Protein; Telomere; Transfection | 1996 |
Histone hyperacetylation plays a role in augmentation of IL-4-induced IgE production in LPS-stimulated murine B-lymphocytes by sodium butyrate.
Topics: Animals; B-Lymphocytes; Butyrates; Butyric Acid; Histone Deacetylase Inhibitors; Hydroxamic Acids; Immunoglobulin E; In Vitro Techniques; Interleukin-4; Kinetics; Lipopolysaccharides; Mice | 1996 |
Involvement of histone hyperacetylation in triggering DNA fragmentation of rat thymocytes undergoing apoptosis.
Topics: Acetylation; Acetyltransferases; Animals; Apoptosis; Butyrates; Butyric Acid; Cells, Cultured; DNA; Enzyme Inhibitors; Histone Acetyltransferases; Histones; Hydroxamic Acids; Kinetics; Rats; Rats, Sprague-Dawley; Saccharomyces cerevisiae Proteins; T-Lymphocytes | 1996 |
Inhibition of IL-8 gene expression in Caco-2 cells by compounds which induce histone hyperacetylation.
Topics: Acetylation; Butyrates; Butyric Acid; Caco-2 Cells; Cell Differentiation; Enzyme Inhibitors; Gene Expression Regulation; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Interleukin-1; Interleukin-8; Phenotype; Propionates; Stimulation, Chemical | 1997 |
Histone acetylation influences thyroid hormone and retinoic acid-mediated gene expression.
Topics: Acetylation; Animals; Butyrates; Butyric Acid; Cells, Cultured; Enzyme Inhibitors; Gene Expression Regulation; Genes, Reporter; Growth Hormone; Histone Deacetylase Inhibitors; Histones; Hydroxamic Acids; Pituitary Gland; Promoter Regions, Genetic; Rats; Receptors, Retinoic Acid; Receptors, Thyroid Hormone; Transcription, Genetic; Transfection; Tretinoin; Triiodothyronine | 1997 |
Reactivation of silenced, virally transduced genes by inhibitors of histone deacetylase.
Topics: Animals; Azacitidine; beta-Galactosidase; Butyrates; Butyric Acid; Cloning, Molecular; Cytomegalovirus; Dependovirus; Enzyme Inhibitors; Gene Expression; Genes, Reporter; Genetic Therapy; Genetic Vectors; Globins; HeLa Cells; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Mice; Polymerase Chain Reaction; Recombinant Proteins; Retroviridae; Transfection; Tumor Cells, Cultured | 1997 |
Apoptotic death in adenocarcinoma cell lines induced by butyrate and other histone deacetylase inhibitors.
Topics: Adenocarcinoma; Apoptosis; Butyrates; Butyric Acid; Colonic Neoplasms; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fatty Acids, Volatile; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1997 |
Epigenetic silencing of RNA polymerase I transcription: a role for DNA methylation and histone modification in nucleolar dominance.
Topics: Azacitidine; Brassica; Butyrates; Butyric Acid; Cell Nucleolus; Cytosine; Decitabine; DNA Methylation; Enzyme Inhibitors; Gene Expression Regulation, Plant; Genes, Dominant; Histones; Hydroxamic Acids; Polyploidy; RNA Polymerase I; RNA, Ribosomal; Transcription, Genetic | 1997 |
Induction of caspase-3 protease activity and apoptosis by butyrate and trichostatin A (inhibitors of histone deacetylase): dependence on protein synthesis and synergy with a mitochondrial/cytochrome c-dependent pathway.
Topics: Apoptosis; bcl-2-Associated X Protein; Butyrates; Butyric Acid; Caspase 3; Caspases; Cells, Cultured; Cycloheximide; Cysteine Endopeptidases; Cytochrome c Group; DNA Fragmentation; DNA, Neoplasm; Enzyme Induction; Histone Deacetylases; Humans; Hydroxamic Acids; Jurkat Cells; Protein Biosynthesis; Protein Kinase Inhibitors; Protein Synthesis Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Staurosporine | 1997 |
Macrophage inflammatory protein-2: chromosomal regulation in rat small intestinal epithelial cells.
Topics: Acetylation; Animals; Butyrates; Butyric Acid; Chemokine CXCL2; Chemotactic Factors; Chromosomes; Culture Techniques; Epithelial Cells; Epithelium; Histones; Hydroxamic Acids; Interleukin-1; Intestine, Small; Lipopolysaccharides; Monokines; Rats; RNA, Messenger | 1997 |
Expression of mutant dynamin inhibits toxicity and transport of endocytosed ricin to the Golgi apparatus.
Topics: Biological Transport; Butyrates; Butyric Acid; Cell Division; Dynamins; Endocytosis; Enzyme Inhibitors; Golgi Apparatus; GTP Phosphohydrolases; HeLa Cells; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Lysosomes; Morpholines; Mutation; Protein Biosynthesis; Receptor, IGF Type 2; Ricin; Temperature; Tetracycline | 1998 |
Characterization of a human RPD3 ortholog, HDAC3.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Base Sequence; Butyrates; Butyric Acid; DNA, Complementary; Gene Expression; Gene Library; Histone Deacetylase 1; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Hydroxamic Acids; Molecular Sequence Data; Nuclear Proteins; Nucleosomes; Peptides; Sequence Homology, Amino Acid; Transcription Factors | 1998 |
Histone deacetylase inhibitors up-regulate the expression of cell surface MHC class-I molecules in B16/BL6 cells.
Topics: Animals; Bacillus megaterium; Butyrates; Butyric Acid; Enzyme Inhibitors; Hemiterpenes; Histocompatibility Antigens Class I; Histone Deacetylase Inhibitors; Hydroxamic Acids; Melanoma, Experimental; Mice; Pentanoic Acids; Up-Regulation | 1998 |
Histone acetylation is required to maintain the unfolded nucleosome structure associated with transcribing DNA.
Topics: Acetylation; Animals; Butyrates; Butyric Acid; Chickens; Chromatin; Chromatography, Affinity; Cysteine; Erythrocytes; Histone Deacetylase Inhibitors; Histones; Hydroxamic Acids; Nucleosomes; Sulfhydryl Reagents; Transcription, Genetic | 1998 |
Differential expression of human histone deacetylase mRNAs in response to immune cell apoptosis induction by trichostatin A and butyrate.
Topics: Acetyltransferases; Apoptosis; Butyrates; Butyric Acid; CD4-Positive T-Lymphocytes; Cell Cycle; Cell Division; Down-Regulation; Flow Cytometry; Gene Expression Regulation; Genes, p53; Histone Acetyltransferases; Histone Deacetylases; Humans; Hydroxamic Acids; Interferon-gamma; Isoenzymes; Phytohemagglutinins; RNA, Messenger; Saccharomyces cerevisiae Proteins; Thymidine; Up-Regulation | 1998 |
Quantitative PCR analysis of HbF inducers in primary human adult erythroid cells.
Topics: Adult; Azacitidine; Butyric Acid; DNA, Complementary; Erythroid Precursor Cells; Erythropoietin; Fetal Hemoglobin; Gene Expression Regulation; Globins; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Hydroxyurea; Polymerase Chain Reaction; RNA, Messenger | 2000 |
Sp1 and chromatin environment are important contributors to the formation of repressive chromatin structures on the transfected human adenine nucleotide translocase-2 promoter.
Topics: 3T3 Cells; Acetylation; Animals; Butyric Acid; Chromatin; Gene Silencing; Genes, Reporter; Genome; HeLa Cells; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Mice; Mitochondrial ADP, ATP Translocases; Molecular Conformation; Mutation; Promoter Regions, Genetic; Recombination, Genetic; Response Elements; Sp1 Transcription Factor; Transcriptional Activation; Transfection | 2000 |
Mechanism for inactivation of the KIP family cyclin-dependent kinase inhibitor genes in gastric cancer cells.
Topics: Azacitidine; Butyric Acid; CDC2 Protein Kinase; Cell Cycle Proteins; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinase Inhibitor p57; Decitabine; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Microtubule-Associated Proteins; Nuclear Proteins; Restriction Mapping; Reverse Transcriptase Polymerase Chain Reaction; Stomach Neoplasms; Transcription, Genetic; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2000 |
Modulation of complement component (C3 and factor B) biosynthesis by a histone deacetylase inhibitor in human intestinal epithelial cells.
Topics: Blotting, Northern; Butyric Acid; CCAAT-Enhancer-Binding Proteins; Complement C3; Complement Factor B; DNA-Binding Proteins; Enzyme Inhibitors; Epithelial Cells; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Intestinal Mucosa; NF-kappa B; Nuclear Proteins; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2000 |
Synergistic growth inhibition of prostate cancer cells by 1 alpha,25 Dihydroxyvitamin D(3) and its 19-nor-hexafluoride analogs in combination with either sodium butyrate or trichostatin A.
Topics: Antineoplastic Agents; Apoptosis; Butyric Acid; Calcitriol; Cell Cycle; Cholecalciferol; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cytochrome P-450 Enzyme System; Drug Synergism; Enzyme Inhibitors; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Male; Prostatic Neoplasms; Steroid Hydroxylases; Transcriptional Activation; Tumor Cells, Cultured; Vitamin D3 24-Hydroxylase | 2001 |
Reversal of methylation-mediated repression with short-chain fatty acids: evidence for an additional mechanism to histone deacetylation.
Topics: Animals; beta-Galactosidase; Butyric Acid; Caproates; Cell Line; Chromatin; DNA; DNA Footprinting; DNA Methylation; Drug Synergism; Ecdysterone; Fatty Acids, Volatile; Gene Expression Regulation; Gene Silencing; Histone Deacetylases; Histones; Humans; Hydroxamic Acids; Kinetics; Lac Operon; Plasmids; Promoter Regions, Genetic; Time Factors | 2001 |
Transcriptional repression of ErbB2 by histone deacetylase inhibitors detected by a genomically integrated ErbB2 promoter-reporting cell screen.
Topics: Blotting, Western; Breast Neoplasms; Butyric Acid; Cell Survival; Deoxyribonuclease I; DNA Probes; Down-Regulation; Drug Resistance, Neoplasm; Enzyme Inhibitors; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Luciferases; Nucleotide Mapping; Promoter Regions, Genetic; Receptor, ErbB-2; Response Elements; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 2002 |
Potentiation of tumor necrosis factor-induced NF-kappa B activation by deacetylase inhibitors is associated with a delayed cytoplasmic reappearance of I kappa B alpha.
Topics: Animals; Butyric Acid; Cysteine Endopeptidases; Cytoplasm; Enzyme Inhibitors; HeLa Cells; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; I-kappa B Kinase; I-kappa B Proteins; Leupeptins; Mitogen-Activated Protein Kinases; Multienzyme Complexes; NF-kappa B; NF-KappaB Inhibitor alpha; Proteasome Endopeptidase Complex; Protein Serine-Threonine Kinases; Protein Transport; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2003 |
Histone deacetylase inhibitors induce a senescence-like state in human cells by a p16-dependent mechanism that is independent of a mitotic clock.
Topics: Animals; Butyric Acid; Cell Division; Cell Line; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p16; Diploidy; Enzyme Inhibitors; Fetus; Fibroblasts; Gene Expression Regulation; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Karyotyping; Mice; Papillomaviridae; Precipitin Tests; Retinoblastoma Protein; Signal Transduction; Skin; Species Specificity; Tumor Suppressor Protein p53; Up-Regulation | 2004 |
Histone deacetylase inhibitors, N-butyric acid and trichostatin A, induce caspase-8- but not caspase-9-dependent apoptosis in human malignant glioma cells.
Topics: Apoptosis; Brain Neoplasms; Butyric Acid; Caspase 8; Caspase 9; Caspases; Cell Cycle; Cell Cycle Proteins; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Enzyme Induction; Enzyme Inhibitors; Glioma; Histamine Antagonists; Humans; Hydroxamic Acids | 2005 |
Nuclear levels and patterns of histone H3 modification and HP1 proteins after inhibition of histone deacetylases.
Topics: Apoptosis; Butyric Acid; Carcinoma, Small Cell; Cell Cycle; Cell Line; Cell Line, Tumor; Cell Nucleus; Chromatin; Chromobox Protein Homolog 5; Chromosomal Proteins, Non-Histone; Colonic Neoplasms; Enzyme Inhibitors; Fetus; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; HT29 Cells; Humans; Hydroxamic Acids; Interphase; Lung Neoplasms | 2005 |
Histone deacetylase inhibitors promote osteoblast maturation.
Topics: Acetylation; Alkaline Phosphatase; Animals; Benzamides; Butyric Acid; Calcification, Physiologic; Calcium; Cell Cycle; Cell Differentiation; Cell Line; Cell Shape; Cell Survival; Cells, Cultured; Collagen Type I; Core Binding Factor Alpha 1 Subunit; Enzyme Inhibitors; Gene Expression; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Hydroxamic Acids; Integrin-Binding Sialoprotein; Mice; Organ Culture Techniques; Osteoblasts; Osteocalcin; Osteopontin; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; Sialoglycoproteins; Skull; Valproic Acid | 2005 |
Effects of the histone deacetylases inhibitors sodium butyrate and trichostatin A on the inhibition of gap junctional intercellular communication by H2O2- and 12-O-tetradecanoylphorbol-13-acetate in rat liver epithelial cells.
Topics: Animals; Butyric Acid; Carcinogens; Cell Communication; Cells, Cultured; Enzyme Inhibitors; Epithelial Cells; Gap Junctions; Histamine Antagonists; Histone Deacetylase Inhibitors; Hydrogen Peroxide; Hydroxamic Acids; Liver; Mitogen-Activated Protein Kinases; Oxidants; Phosphorylation; Rats; Tetradecanoylphorbol Acetate | 2006 |
HDAC inhibitors TSA and sodium butyrate enhanced the human IL-5 expression by altering histone acetylation status at its promoter region.
Topics: Acetylation; Butyric Acid; Cell Line; Chromatin Immunoprecipitation; Enzyme Inhibitors; Gene Expression; Genes, Reporter; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Interleukin-5; Ionomycin; Jurkat Cells; Mutagenesis, Site-Directed; Promoter Regions, Genetic; Response Elements; Tetradecanoylphorbol Acetate; Transfection | 2007 |
Trichostatin A effects on gene expression in the protozoan parasite Entamoeba histolytica.
Topics: Animals; Butyric Acid; Entamoeba histolytica; Gene Expression Profiling; Gene Expression Regulation; Genes, Protozoan; Histones; Hydroxamic Acids; Oligonucleotide Array Sequence Analysis; Propionates; Reverse Transcriptase Polymerase Chain Reaction; Sodium Acetate | 2007 |
Histone deacetylase inhibition in colorectal cancer cells reveals competing roles for members of the oncogenic miR-17-92 cluster.
Topics: Adaptor Proteins, Signal Transducing; Adenocarcinoma; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Butyric Acid; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Down-Regulation; Gene Expression Regulation, Neoplastic; HCT116 Cells; Histone Deacetylase Inhibitors; HT29 Cells; Humans; Hydroxamic Acids; Membrane Proteins; MicroRNAs; Phosphoproteins; Proto-Oncogene Proteins; PTEN Phosphohydrolase; RNA, Long Noncoding; RNA, Messenger; Transfection; Vorinostat | 2013 |
Deacetylation of p53 induces autophagy by suppressing Bmf expression.
Topics: Acetylation; Adaptor Proteins, Signal Transducing; Animals; Autophagy; Butyric Acid; Cell Nucleus; Cells, Cultured; Epithelial Cells; Gene Expression; Gene Silencing; Histone Deacetylase 1; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Interferon-gamma; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Promoter Regions, Genetic; Protein Processing, Post-Translational; Respiratory Mucosa; Tumor Suppressor Protein p53 | 2013 |
A proapoptotic effect of valproic acid on progenitors of embryonic stem cell-derived glutamatergic neurons.
Topics: Acetylation; Animals; Anticonvulsants; Apoptosis; Butyric Acid; Cell Line; Cells, Cultured; Embryonic Stem Cells; Histone Deacetylase Inhibitors; Histones; Hydroxamic Acids; Mice; Neural Stem Cells; Neurons; Protein Processing, Post-Translational; Valproic Acid | 2013 |
Histone deacetylases inhibitor trichostatin A increases the expression of Dleu2/miR-15a/16-1 via HDAC3 in non-small cell lung cancer.
Topics: Acetylation; Apoptosis; Butyric Acid; Carcinoma, Non-Small-Cell Lung; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Hydroxamic Acids; Lung Neoplasms; MicroRNAs; Promoter Regions, Genetic; Proto-Oncogene Proteins c-bcl-2; RNA, Long Noncoding; Transferases; Tumor Stem Cell Assay; Tumor Suppressor Proteins; Up-Regulation | 2013 |
Basolateral amygdala activity is required for enhancement of memory consolidation produced by histone deacetylase inhibition in the hippocampus.
Topics: Animals; Basolateral Nuclear Complex; Butyric Acid; Hippocampus; Histone Deacetylase Inhibitors; Hydroxamic Acids; Male; Memory; Rats, Wistar | 2014 |
Histone acetylation in astrocytes suppresses GFAP and stimulates a reorganization of the intermediate filament network.
Topics: Acetylation; Alexander Disease; Alternative Splicing; Astrocytes; Butyric Acid; Cell Line, Tumor; Cytoskeleton; Epigenesis, Genetic; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Hydroxamic Acids; Protein Aggregates; Protein Isoforms; Protein Multimerization | 2014 |
Reciprocal modulation of histone deacetylase inhibitors sodium butyrate and trichostatin A on the energy metabolism of breast cancer cells.
Topics: Breast Neoplasms; Butyric Acid; Cell Line, Tumor; Energy Metabolism; Glycolysis; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Metabolic Networks and Pathways; Oxidation-Reduction | 2015 |
Regulation of TWIK-related potassium channel-1 (Trek1) restitutes intestinal epithelial barrier function.
Topics: Animals; Butyric Acid; Cell Line; Clostridium butyricum; Cytokines; Eosinophils; Epithelial Cells; Gene Expression Regulation; Histone Deacetylase 1; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Hypersensitivity; Intestinal Mucosa; Mast Cells; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; Ovalbumin; Potassium Channels, Tandem Pore Domain; Probiotics; Signal Transduction | 2016 |
Histone Deacetylase Inhibitors (HDACi) Cause the Selective Depletion of Bromodomain Containing Proteins (BCPs).
Topics: Acetylation; Butyric Acid; Carrier Proteins; Cell Cycle Proteins; Co-Repressor Proteins; CREB-Binding Protein; DNA-Binding Proteins; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Silencing; HeLa Cells; Histone Acetyltransferases; Histone Chaperones; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Hydroxamic Acids; Nuclear Proteins; Protein Processing, Post-Translational; RNA, Small Interfering; Transcription Factors; Transcription, Genetic; Vorinostat | 2015 |
TRPM2 mediates histone deacetylase inhibition-induced apoptosis in bladder cancer cells.
Topics: Apoptosis; Butyric Acid; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Promoter Regions, Genetic; TRPM Cation Channels; Up-Regulation; Urinary Bladder Neoplasms | 2015 |
Histone deacetylases inhibitors effects on Cryptococcus neoformans major virulence phenotypes.
Topics: Animals; Butyric Acid; Cell Division; Cryptococcus neoformans; Disease Models, Animal; Fungal Capsules; Histone Deacetylase Inhibitors; Hydroxamic Acids; Lepidoptera; Melanins; Microbial Viability; Phenotype; Phospholipases; Survival Analysis; Temperature; Virulence | 2015 |
Histone deacetylase inhibitors promote the expression of ATP2A3 gene in breast cancer cell lines.
Topics: Breast Neoplasms; Butyric Acid; Cell Line, Tumor; CpG Islands; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; MCF-7 Cells; Promoter Regions, Genetic; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Up-Regulation | 2016 |
Histone Deacetylase Inhibitors Activate Tristetraprolin Expression through Induction of Early Growth Response Protein 1 (EGR1) in Colorectal Cancer Cells.
Topics: Butyric Acid; Cell Line, Tumor; Colorectal Neoplasms; Cyclooxygenase 2; Early Growth Response Protein 1; Epigenesis, Genetic; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; RNA, Messenger; Tristetraprolin; Vorinostat | 2015 |
Interference of the Histone Deacetylase Inhibits Pollen Germination and Pollen Tube Growth in Picea wilsonii Mast.
Topics: Actin Cytoskeleton; Butyric Acid; Calcium; Cell Wall; Germination; Glucans; Histone Deacetylase Inhibitors; Histone Deacetylases; Hydroxamic Acids; Pectins; Picea; Pollen; Pollen Tube | 2015 |
Histone deacetylase inhibitors interfere with angiogenesis by decreasing endothelial VEGFR-2 protein half-life in part via a VE-cadherin-dependent mechanism.
Topics: Antigens, CD; Butyric Acid; Cadherins; Endothelium; Gene Expression; Gene Knockdown Techniques; Half-Life; Histone Deacetylase 1; Histone Deacetylase 6; Histone Deacetylase Inhibitors; Histone Deacetylases; Human Umbilical Vein Endothelial Cells; Humans; Hydroxamic Acids; Neovascularization, Physiologic; Repressor Proteins; RNA, Messenger; RNA, Small Interfering; Valproic Acid; Vascular Endothelial Growth Factor Receptor-2 | 2017 |
The expression of tumor suppressor gene Cyld is upregulated by histone deacetylace inhibitors in human hepatocellular carcinoma cell lines.
Topics: Butyric Acid; Carcinoma, Hepatocellular; Cell Line, Tumor; Deubiquitinating Enzyme CYLD; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Liver Neoplasms; Tumor Suppressor Proteins; Up-Regulation; Vorinostat | 2016 |
Down-regulation of Claudin-2 Expression and Proliferation by Epigenetic Inhibitors in Human Lung Adenocarcinoma A549 Cells.
Topics: A549 Cells; Adenocarcinoma; Adenocarcinoma of Lung; Azacitidine; Butyric Acid; Cell Proliferation; Chromones; Claudin-2; Down-Regulation; Epigenesis, Genetic; Humans; Hydroxamic Acids; Lung Neoplasms; MicroRNAs; Morpholines; Nitriles; RNA, Messenger; Signal Transduction; Sulfones | 2017 |
Histone deacetylase inhibitors suppress immature dendritic cell's migration by regulating CC chemokine receptor 1 expression.
Topics: Animals; Butyric Acid; Cell Differentiation; Cell Movement; Cells, Cultured; Chemokine CCL3; Dendritic Cells; Down-Regulation; Histone Deacetylase Inhibitors; Hydroxamic Acids; Hydroxylamines; Mice; Mice, Inbred C57BL; Quinolines; Receptors, CCR1 | 2017 |
Curcumin inhibits hepatitis B virus infection by down-regulating cccDNA-bound histone acetylation.
Topics: Acetylation; Antiviral Agents; Butyric Acid; Chromatin Immunoprecipitation; Curcumin; DNA Replication; DNA, Circular; DNA, Viral; Dose-Response Relationship, Drug; Down-Regulation; Drug Synergism; E1A-Associated p300 Protein; Hep G2 Cells; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Real-Time Polymerase Chain Reaction; RNA Interference; RNA, Small Interfering | 2017 |
Butyrate promotes visceral hypersensitivity in an IBS-like model via enteric glial cell-derived nerve growth factor.
Topics: Animals; Butyric Acid; Cell Line; Disease Models, Animal; Enteric Nervous System; Gene Expression Profiling; Histone Deacetylase Inhibitors; Hydroxamic Acids; Irritable Bowel Syndrome; Male; Nerve Growth Factor; Neuroglia; Rats, Sprague-Dawley; Transcriptome; Visceral Pain | 2018 |
Induction of colon and cervical cancer cell death by cinnamic acid derivatives is mediated through the inhibition of Histone Deacetylases (HDAC).
Topics: Apoptosis; Binding Sites; Butyric Acid; Cell Line, Tumor; Cinnamates; Colorectal Neoplasms; Female; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Uterine Cervical Neoplasms | 2017 |
High dose of histone deacetylase inhibitors affects insulin secretory mechanism of pancreatic beta cell line.
Topics: Animals; Butyric Acid; Cattle; Cell Line; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Insulin; Insulin-Secreting Cells; Valproic Acid | 2018 |
Rapid and transient oxygen consumption increase following acute HDAC/KDAC inhibition in Drosophila tissue.
Topics: Acetylation; Animals; Butyric Acid; Drosophila melanogaster; Drosophila Proteins; Female; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Hydroxamic Acids; Male; Oxygen Consumption | 2018 |
Histone deacetylase inhibitors promote ATP2A3 gene expression in hepatocellular carcinoma cells: p300 as a transcriptional regulator.
Topics: Animals; Butyric Acid; Carcinoma, Hepatocellular; E1A-Associated p300 Protein; Gene Expression; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Liver Neoplasms; Promoter Regions, Genetic; Rats; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Tumor Cells, Cultured | 2019 |
Different Modes of Action of Genetic and Chemical Downregulation of Histone Deacetylases with Respect to Plant Development and Histone Modifications.
Topics: Arabidopsis; Arabidopsis Proteins; Butyric Acid; DNA Methylation; Gene Expression Regulation, Plant; Gene Silencing; Germination; Histone Code; Histone Deacetylase Inhibitors; Histone Deacetylases; Hydroxamic Acids; Plant Development; Proteomics; Seedlings | 2019 |
Trichostatin A and sodium butyrate promotes plant regeneration in common wheat.
Topics: Butyric Acid; Cell Differentiation; Hydroxamic Acids; Regeneration; Triticum | 2020 |
The role of Cryptococcus neoformans histone deacetylase genes in the response to antifungal drugs, epigenetic modulators and to photodynamic therapy mediated by an aluminium phthalocyanine chloride nanoemulsion in vitro.
Topics: Amphotericin B; Antifungal Agents; Bacterial Proteins; Butyric Acid; Cryptococcosis; Cryptococcus neoformans; Drug Synergism; Emulsions; Epigenesis, Genetic; Fluconazole; Gene Expression Regulation, Bacterial; Histone Deacetylases; Humans; Hydroxamic Acids; Indoles; Nanoparticles; Organometallic Compounds; Photochemotherapy; Sulfamethoxazole | 2021 |
Contribution of histone acetylation to the serotonin-mediated long-term synaptic plasticity in terrestrial snails.
Topics: Animals; Butyric Acid; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Neuronal Plasticity; Serotonin | 2022 |
Histone deacetylase inhibitors inhibit lung adenocarcinoma metastasis via HDAC2/YY1 mediated downregulation of Cdh1.
Topics: Adenocarcinoma of Lung; Animals; Antigens, CD; Butyric Acid; Cadherins; Cell Movement; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Histone Deacetylase 2; Histone Deacetylase Inhibitors; Humans; Mice; Neoplasm Metastasis; Protein Binding; Transcription, Genetic; Transforming Growth Factor beta; YY1 Transcription Factor | 2023 |