butyric acid and hydroxyurea

butyric acid has been researched along with hydroxyurea in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199012 (42.86)18.7374
1990's9 (32.14)18.2507
2000's1 (3.57)29.6817
2010's5 (17.86)24.3611
2020's1 (3.57)2.80

Authors

AuthorsStudies
Agricola, B; Byrne, E; Donahue, RE; Dover, GJ; McDonagh, KT; Nathan, DG; Nienhuis, AW1
Constantoulakis, P; Costantini, F; Fry, D; Josephson, B; Mangahas, L; Stamatoyannopoulos, G1
Hanotte, O; Menozzi, FD; Miller, AO1
Gálfi, P; Kutas, F; Neogrády, S; Veresegyházy, T1
Hare, JD1
Cox, GS; Park, KH1
Aller, P; Hirschhorn, RR; Rius, C1
Waalkes, MP; Wilson, MJ1
Hashimoto, Y; Masuko, T; Takahashi, N; Yagita, H1
Kimura, G; Ohtsu, M; Yamada, K1
Ghosh, NK1
Butt, TR; Sreevalsan, T1
Smerdon, MJ1
Hofbauer, R; Müllner, E; Wintersberger, E1
Craig, JE; Rochette, J; Thein, SL1
DeSimone, J; Heller, P; Lavelle, D1
Fibach, E; Prasanna, P; Rodgers, GP; Samid, D1
Olivieri, NF1
Loukopoulos, D1
Hillen, HF; Saleh, AW1
Blanchette-Mackie, EJ; Dwyer, N; Fibach, E; Hasegawa, S; Noguchi, CT; Rodgers, GP; Schechter, AN; Uyesaka, N1
Li, J; Noguchi, CT; Schechter, AN; Smith, RD1
Cappellini, MD; Fossati, G; Modena, D; Porretti, L; Ronzoni, L; Sonzogni, L; Trombetta, E1
Chao, YS; Chen, RL; Chou, YC; Lai, ZS; Shen, CK; Song, JS1
Kapler, GM; Lee, PH; Meng, X; Sandoval, PY1
Barbarani, G; Cappella, P; Durlak, M; Elangovan, S; Font-Monclus, I; Fraietta, I; Fugazza, C; Gasparri, F; Marini, MG; Marongiu, MF; Mauri, M; Moi, P; Ottolenghi, S; Ronchi, A1
Fisher, CA; Gibbons, RJ; Higgs, DR; Mettananda, S; Oppermann, U; Sloane-Stanley, JA; Taylor, S1
Borghetto, V; Costanzo, E; Di Bella, G; Di Bella, L; Moscato, I1

Reviews

5 review(s) available for butyric acid and hydroxyurea

ArticleYear
Fetal hemoglobin levels in adults.
    Blood reviews, 1994, Volume: 8, Issue:4

    Topics: Adult; Azacitidine; Base Sequence; Butyrates; Butyric Acid; Fetal Hemoglobin; Gene Expression Regulation; Genetic Therapy; Globins; Humans; Hydroxyurea; Molecular Sequence Data; Sequence Deletion; Thalassemia

1994
Fetal hemoglobin reactivation in baboon and man: a short perspective.
    American journal of hematology, 1993, Volume: 42, Issue:1

    Topics: Anemia, Sickle Cell; Animals; Azacitidine; Butyrates; Butyric Acid; Erythropoietin; Fetal Hemoglobin; Humans; Hydroxyurea; Papio

1993
Reactivation of fetal hemoglobin in patients with beta-thalassemia.
    Seminars in hematology, 1996, Volume: 33, Issue:1

    Topics: Azacitidine; beta-Thalassemia; Butyrates; Butyric Acid; Erythropoietin; Fetal Hemoglobin; Homozygote; Humans; Hydroxyurea; Treatment Outcome

1996
New therapies for the haemoglobinopathies.
    Journal of internal medicine. Supplement, 1997, Volume: 740

    Topics: Anemia, Sickle Cell; Antisickling Agents; Butyrates; Butyric Acid; Drug Therapy, Combination; Erythropoietin; Hemoglobinopathies; Humans; Hydroxyurea; Thalassemia

1997
Pharmacological induction of foetal haemoglobin synthesis in sickle-cell disease.
    The Netherlands journal of medicine, 1997, Volume: 51, Issue:5

    Topics: Anemia, Sickle Cell; Animals; Butyrates; Butyric Acid; Erythropoietin; Fetal Hemoglobin; Humans; Hydroxyurea; Infant, Newborn

1997

Other Studies

23 other study(ies) available for butyric acid and hydroxyurea

ArticleYear
Hydroxyurea-induced HbF production in anemic primates: augmentation by erythropoietin, hematopoietic growth factors, and sodium butyrate.
    Experimental hematology, 1992, Volume: 20, Issue:10

    Topics: Administration, Oral; Anemia; Animals; Bloodletting; Butyrates; Butyric Acid; Cell Division; Chromatography, High Pressure Liquid; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Erythrocytes; Erythropoietin; Female; Fetal Hemoglobin; Granulocyte-Macrophage Colony-Stimulating Factor; Hematocrit; Hematopoietic Cell Growth Factors; Hydroxyurea; Injections, Intravenous; Interleukin-3; Macaca mulatta; Reticulocytes; Time Factors

1992
A transgenic mouse model for studying the induction of fetal hemoglobin in the adult.
    Transactions of the Association of American Physicians, 1990, Volume: 103

    Topics: Adult; Animals; Azacitidine; Butyrates; Butyric Acid; Fetal Hemoglobin; Gene Expression; Globins; Humans; Hydroxyurea; Mice; Mice, Transgenic; Models, Biological

1990
Stimulation of protein accumulation in HeLa cells by inhibitors of DNA replication. Ferritin.
    FEBS letters, 1985, Nov-25, Volume: 193, Issue:1

    Topics: Aphidicolin; Azacitidine; Butyrates; Butyric Acid; Diterpenes; DNA Polymerase II; Ferritins; HeLa Cells; Humans; Hydroxyurea; Interphase; Iron; Thymidine

1985
Influence of sodium butyrate on HeLa cell morphology and proliferation.
    Life sciences, 1985, Dec-16, Volume: 37, Issue:24

    Topics: Alkaline Phosphatase; Butyrates; Butyric Acid; Cell Differentiation; Cell Division; Cytoskeleton; HeLa Cells; Humans; Hydroxyurea; Intermediate Filaments; Keratins; Membrane Proteins; Protein Precursors

1985
Two-color flow-cytometric analysis of the growth cycle of Plasmodium falciparum in vitro: identification of cell cycle compartments.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1986, Volume: 34, Issue:12

    Topics: Animals; Aphidicolin; Butyrates; Butyric Acid; Cell Compartmentation; Cell Cycle; Diterpenes; DNA Replication; Flow Cytometry; Hydroxyurea; Plasmodium falciparum; RNA

1986
Modulation of glycoprotein hormone alpha-subunit levels, alkaline phosphatase activity, and DNA replication by antimetabolites in HeLa cultures.
    Archives of biochemistry and biophysics, 1989, Volume: 268, Issue:1

    Topics: Alkaline Phosphatase; Antimetabolites; Butyrates; Butyric Acid; Cytarabine; DNA Replication; DNA, Neoplasm; Glycoprotein Hormones, alpha Subunit; HeLa Cells; Humans; Hydroxyurea; Kinetics; Methotrexate

1989
Modification of cell growth-dependent gene transcript levels by sodium butyrate in serum stimulated fibroblasts.
    Biochemistry international, 1989, Volume: 18, Issue:1

    Topics: Animals; Blood; Butyrates; Butyric Acid; Cell Cycle; Cell Division; Cell Line; Culture Media; Cytarabine; Fibroblasts; Gene Expression Regulation; Genes; Hydroxyurea; Mitoguazone; Mutation; RNA, Messenger; Temperature

1989
Enhancement of cadmium-induced metallothionein synthesis in cultured TRL 1215 cells by butyric acid pretreatment.
    Toxicology letters, 1986, Volume: 32, Issue:3

    Topics: Animals; Butyrates; Butyric Acid; Cadmium; Cell Line; Drug Interactions; Hydroxyurea; In Vitro Techniques; Liver; Metallothionein; Rats; Rats, Inbred F344

1986
Monoclonal antibodies that inhibit activation and proliferation of lymphocytes. I. Expression of the antigen on monocytes and activated lymphocytes.
    Journal of immunology (Baltimore, Md. : 1950), 1986, Mar-15, Volume: 136, Issue:6

    Topics: Animals; Antibodies, Monoclonal; Butyrates; Butyric Acid; Cell Cycle; Flow Cytometry; Humans; Hydroxyurea; Lymphocyte Activation; Lymphocytes; Monocytes; Rats; Time Factors

1986
Isolation of tetraploid clones with high efficiency from diploid 3Y1 rat fibroblasts treated with sodium butyrate.
    In vitro cellular & developmental biology : journal of the Tissue Culture Association, 1985, Volume: 21, Issue:8

    Topics: Animals; Butyrates; Butyric Acid; Cell Count; Cell Division; Cell Line; Clone Cells; Fibroblasts; Hydroxyurea; Interphase; Karyotyping; Polyploidy; Proteins; Rats

1985
Drug-induced biochemical markers of cancer in cervical carcinoma cells.
    Clinical biochemistry, 1982, Volume: 15, Issue:1

    Topics: Alkaline Phosphatase; Butyrates; Butyric Acid; Carcinoembryonic Antigen; Chorionic Gonadotropin; Chorionic Gonadotropin, beta Subunit, Human; Female; Follicle Stimulating Hormone; Glycoprotein Hormones, alpha Subunit; GPI-Linked Proteins; HeLa Cells; Humans; Hydatidiform Mole; Hydroxyurea; Isoenzymes; Lung Neoplasms; Peptide Fragments; Pregnancy; Progesterone; Uterine Cervical Neoplasms

1982
Interferon and sodium butyrate inhibit the stimulation of poly(ADP-ribose) synthetase in mouse cells stimulated to divide.
    Experimental cell research, 1983, Oct-15, Volume: 148, Issue:2

    Topics: Animals; Butyrates; Butyric Acid; Cell Cycle; Cells, Cultured; DNA Replication; Floxuridine; Humans; Hydroxyurea; Interferon Type I; Kinetics; Methotrexate; Mice; NAD+ Nucleosidase; Poly(ADP-ribose) Polymerases

1983
Rearrangements of chromatin structure in newly repaired regions of deoxyribonucleic acid in human cells treated with sodium butyrate or hydroxyurea.
    Biochemistry, 1983, Jul-05, Volume: 22, Issue:14

    Topics: Butyrates; Butyric Acid; Chromatin; DNA Repair; Humans; Hydroxyurea; Mathematics; Time Factors; Ultraviolet Rays

1983
Increased levels of dihydrofolate reductase mRNA can be measured in normal, growth-stimulated mouse fibroblasts.
    Biochimica et biophysica acta, 1983, Sep-09, Volume: 740, Issue:4

    Topics: Animals; Butyrates; Butyric Acid; Cell Cycle; Cells, Cultured; Cloning, Molecular; DNA; Fibroblasts; Hydroxyurea; Kinetics; Mice; Nucleic Acid Hybridization; Protein Biosynthesis; RNA, Messenger; Tetrahydrofolate Dehydrogenase

1983
Enhanced fetal hemoglobin production by phenylacetate and 4-phenylbutyrate in erythroid precursors derived from normal donors and patients with sickle cell anemia and beta-thalassemia.
    Blood, 1993, Oct-01, Volume: 82, Issue:7

    Topics: Anemia, Sickle Cell; Azacitidine; beta-Thalassemia; Blotting, Northern; Butyrates; Butyric Acid; Cell Division; Cells, Cultured; DNA Probes; Erythrocytes; Fetal Hemoglobin; Hematopoietic Stem Cells; Humans; Hydroxyurea; Kinetics; Phenylacetates; Phenylbutyrates; Reference Values

1993
Sickling of nucleated erythroid precursors from patients with sickle cell anemia.
    Experimental hematology, 1998, Volume: 26, Issue:4

    Topics: Anemia, Sickle Cell; Bone Marrow Cells; Butyrates; Butyric Acid; Cell Hypoxia; Cell Nucleus; Cells, Cultured; Erythrocytes, Abnormal; Erythroid Precursor Cells; Fetal Hemoglobin; Humans; Hydroxyurea; Microscopy, Confocal; Microscopy, Electron; Oxygen

1998
Quantitative PCR analysis of HbF inducers in primary human adult erythroid cells.
    Blood, 2000, Feb-01, Volume: 95, Issue:3

    Topics: Adult; Azacitidine; Butyric Acid; DNA, Complementary; Erythroid Precursor Cells; Erythropoietin; Fetal Hemoglobin; Gene Expression Regulation; Globins; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Hydroxyurea; Polymerase Chain Reaction; RNA, Messenger

2000
Modulation of gamma globin genes expression by histone deacetylase inhibitors: an in vitro study.
    British journal of haematology, 2014, Volume: 165, Issue:5

    Topics: Adult; Anemia, Sickle Cell; Antigens, CD34; Butyric Acid; Carbamates; Cell Differentiation; Cells, Cultured; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Erythroid Precursor Cells; Erythropoiesis; gamma-Globins; Gene Expression Regulation; Hemoglobins; Histone Deacetylase Inhibitors; Humans; Hydroxyurea

2014
Pharmacological Induction of Human Fetal Globin Gene in Hydroxyurea-Resistant Primary Adult Erythroid Cells.
    Molecular and cellular biology, 2015, Volume: 35, Issue:14

    Topics: Adult; Anemia, Sickle Cell; Animals; Antineoplastic Agents; beta-Thalassemia; Blotting, Western; Butyric Acid; Cell Line, Tumor; Cells, Cultured; Drug Resistance; Erythroid Cells; Fetal Hemoglobin; gamma-Globins; Humans; Hydroxyurea; K562 Cells; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Primary Cell Culture; Reverse Transcriptase Polymerase Chain Reaction; Small Molecule Libraries; Transcriptional Activation

2015
Checkpoint Activation of an Unconventional DNA Replication Program in Tetrahymena.
    PLoS genetics, 2015, Volume: 11, Issue:7

    Topics: Ataxia Telangiectasia Mutated Proteins; Butyric Acid; Cell Division; DNA Damage; DNA Replication; DNA-Binding Proteins; Histone Deacetylase Inhibitors; Histones; Hydroxyurea; Origin Recognition Complex; Phosphorylation; Replication Origin; S Phase Cell Cycle Checkpoints; Tetrahymena thermophila

2015
A Novel High-Content Immunofluorescence Assay as a Tool to Identify at the Single Cell Level γ-Globin Inducing Compounds.
    PloS one, 2015, Volume: 10, Issue:10

    Topics: Anemia, Sickle Cell; beta-Globins; beta-Thalassemia; Butyric Acid; Fetal Hemoglobin; gamma-Globins; Humans; Hydroxyurea; K562 Cells

2015
Selective silencing of α-globin by the histone demethylase inhibitor IOX1: a potentially new pathway for treatment of β-thalassemia.
    Haematologica, 2017, Volume: 102, Issue:3

    Topics: alpha-Globins; Antigens, CD34; beta-Thalassemia; Butyric Acid; Cell Culture Techniques; Enzyme Inhibitors; Erythroid Cells; Gene Expression Profiling; Gene Expression Regulation; Histone Demethylases; Histones; Humans; Hydroxamic Acids; Hydroxyquinolines; Hydroxyurea; Molecular Sequence Annotation; Piperazines; RNA, Small Interfering; Small Molecule Libraries; Tranylcypromine; Vorinostat

2017
A retrospective observational study on cases of osteosarcomas treated with a multitherapy: The rationale and effectiveness.
    Neuro endocrinology letters, 2022, Sep-16, Volume: 43, Issue:3

    Topics: Antioxidants; Bone Neoplasms; Butyric Acid; Humans; Hydroxyurea; Melatonin; Osteosarcoma; Tretinoin

2022