butoxamine has been researched along with atenolol in 42 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 16 (38.10) | 18.7374 |
1990's | 12 (28.57) | 18.2507 |
2000's | 7 (16.67) | 29.6817 |
2010's | 6 (14.29) | 24.3611 |
2020's | 1 (2.38) | 2.80 |
Authors | Studies |
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Philippu, A; Stroehl, U | 1 |
Berney, CE; Derksen, FJ; Robinson, NE; Scott, JS | 1 |
Nurminen, ML; Paakkari, I | 1 |
Takuma, T | 1 |
Brime, J; Costales, M; Díaz, F; Lopez-Sela, P; Marín, B; Vijande, M | 1 |
Bradbury, NA; Dormer, RL; McPherson, MA | 1 |
Jaiswal, N; Malik, KU; Weis, MT | 1 |
Anselmi, E; Candenas, ML | 1 |
Aoki, K; Dohi, Y; Fujimoto, S; Matsuda, T | 1 |
Humphreys-Beher, M; Schneyer, CA | 1 |
Barney, CC; Katovich, MJ | 1 |
Goshima, Y; Kubo, T; Misu, Y | 1 |
DiMicco, JA; Hatfield, SM; Petersen, BH | 1 |
Jirakulsomchok, D; Schneyer, CA; Yu, JH | 1 |
Humphreys-Beher, MG; Schneyer, CA | 1 |
Iijima, T; Philippu, A | 1 |
Fregly, MJ | 1 |
Hughes, JM; Seale, JP; Temple, DM | 1 |
DiBona, GF; Osborn, JL; Thames, MD | 1 |
Goshima, Y; Kubo, T; Misu, Y; Ueda, H | 1 |
Horinouchi, T; Koike, K; Muramatsu, M; Ohki, S; Takayanagi, I | 1 |
Kabeyama, A; Nishio, A; Obi, T | 1 |
Biltz, J; Catania, A; Ceriani, G; Lipton, JM; Macaluso, A; McCoy, D; Watanabe, T | 1 |
Kemp, GJ; Odoom, JE; Radda, GK | 1 |
Brennan, FX; Cobb, CL; Maier, SF; Silbert, LH; Watkins, LR | 1 |
Fujimoto, S; Itoh, T | 1 |
Barsh, GS; Catania, A; Furukawa, S; Ichiyama, T; Lipton, JM; Sakai, T | 1 |
Horinouchi, T; Koike, K | 1 |
Capuzzo, A; Fabbri, E; Moon, TW; Selva, C | 1 |
Horinouchi, T; Koike, K; Nakagawa, Y; Wakabayashi, M | 1 |
Akimoto, Y; Horinouchi, T; Koike, K; Tanaka, Y | 1 |
Anesini, C; Borda, E; Coussio, J; Ferraro, G; Turner, S | 1 |
Avolio, AP; Cockcroft, JR; McEniery, CM; Qasem, A; Schmitt, M; Webb, DJ; Wilkinson, IB | 1 |
Gulia, KK; Kumar, VM; Mallick, HN | 1 |
Horinouchi, T; Koike, K; Michikawa, H; Tanaka, Y; Yamashita, Y | 1 |
Froehlich, D; Graf, B; Gruber, M; Lunz, D; Trabold, B | 1 |
Fukui, H; Iwachido, T; Miwa, E; Suyama, Y | 1 |
Canteras, NS; Carobrez, AP; Pavesi, E | 1 |
Alzate, WD; Calderon, GM; Cook, KM; Kotamarti, S; Livingston, DH; Mohr, AM; Pasupuleti, LV; Sifri, ZC | 1 |
Choi, S; Jun, JY; Kim, MY; Kim, YD; Lee, J; Park, CG; Park, IK; Park, JS; Shin, DH; So, I; Wu, MJ | 1 |
Collares, EF; Vinagre, AM | 1 |
Goto, S; Hayashi, K; Ishizuka, K; Kondo, H; Miyazawa, K; Muramatsu, R; Sato, T; Sekiya, T; Takeguchi, A; Togari, A; Uchibori, S | 1 |
42 other study(ies) available for butoxamine and atenolol
Article | Year |
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beta-Adrenoreceptors of the posterior hypothalamus.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Atenolol; Blood Pressure; Butoxamine; Cats; Electric Stimulation; Female; Hypothalamus; Hypothalamus, Posterior; Isoproterenol; Male; Metaproterenol; Receptors, Adrenergic; Receptors, Adrenergic, beta; Terbutaline | 1978 |
Beta-adrenergic receptor activity in ponies with recurrent obstructive pulmonary disease.
Topics: Aerosols; Animals; Atenolol; Butoxamine; Histamine; Horse Diseases; Horses; Isoproterenol; Lung Diseases, Obstructive; Propranolol; Receptors, Adrenergic, beta; Recurrence; Respiratory Function Tests | 1991 |
Role of peripheral and central catecholaminergic and cholinergic mechanisms in the cardiovascular effects of thyrotropin-releasing hormone.
Topics: Animals; Atenolol; Atropine Derivatives; Blood Pressure; Brain; Butoxamine; Cerebral Ventricles; Fenclonine; Haloperidol; Heart Rate; Injections, Intraperitoneal; Injections, Intraventricular; Male; Prazosin; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Thyrotropin-Releasing Hormone; Reserpine; Thyrotropin-Releasing Hormone; Vagotomy; Yohimbine | 1991 |
Propranolol inhibits cyclic AMP accumulation and amylase secretion in parotid acinar cells stimulated by isobutylmethylxanthine and forskolin.
Topics: 1-Methyl-3-isobutylxanthine; Alprenolol; Amylases; Animals; Atenolol; Butoxamine; Colforsin; Cyclic AMP; Male; Membrane Proteins; Parotid Gland; Poly(ADP-ribose) Polymerases; Propranolol; Rats; Rats, Inbred Strains; Saponins; Theophylline | 1990 |
Attenuation of insulin-induced drinking by beta-adrenoceptor antagonists.
Topics: Animals; Atenolol; Blood Glucose; Butoxamine; Drinking; Insulin; Insulin Antagonists; Male; Phenoxybenzamine; Propranolol; Rats; Rats, Inbred Strains; Sympathetic Nervous System | 1991 |
Introduction of cyclic AMP phosphodiesterase into rat submandibular acini prevents isoproterenol-stimulated cyclic AMP rise without affecting mucin secretion.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Atenolol; Butoxamine; Cyclic AMP; In Vitro Techniques; Isoproterenol; Mucins; Osmolar Concentration; Permeability; Rats; Rats, Inbred Strains; Secretory Rate; Submandibular Gland | 1989 |
Mechanism of action of adrenergic and cholinergic stimuli on cardiac prostaglandin synthesis.
Topics: Acetylcholine; Animals; Atenolol; Butoxamine; Dobutamine; Heart; In Vitro Techniques; Isoproterenol; Myocardium; Propanolamines; Prostaglandins; Rabbits; Receptors, Adrenergic, beta; Receptors, Cholinergic | 1989 |
A study of beta-adrenoceptors in rat lung parenchymal strip.
Topics: Albuterol; Animals; Atenolol; Butoxamine; In Vitro Techniques; Isoproterenol; Lung; Male; Norepinephrine; Propranolol; Rats; Receptors, Adrenergic, beta | 1989 |
Altered vascular beta adrenoceptor-mediated relaxation in deoxycorticosterone-salt hypertensive rats.
Topics: Animals; Atenolol; Bucladesine; Butoxamine; Desoxycorticosterone; Fenoterol; Hypertension; Isoproterenol; Male; Norepinephrine; Papaverine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Sodium Chloride; Vasodilation | 1988 |
Effects of chronic isoproterenol administration on beta 1-adrenoceptors and growth of pancreas of young and adult rats.
Topics: Aging; Animals; Atenolol; Butoxamine; Cell Differentiation; Cell Membrane; Dihydroalprenolol; DNA; Isoproterenol; Pancreas; Parotid Gland; Quinuclidinyl Benzilate; Rats; Receptors, Adrenergic, beta | 1988 |
Effect of beta-adrenergic antagonists on experimentally induced drinking in female rats.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Animals; Atenolol; Butoxamine; Drinking; Female; Hypertonic Solutions; Propranolol; Rats; Rats, Inbred Strains; Sodium Chloride; Stereoisomerism; Water Deprivation | 1985 |
Autoregulation of endogenous epinephrine release via presynaptic adrenoceptors in the rat hypothalamic slice.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Atenolol; Benzylamines; Butoxamine; Chromatography, High Pressure Liquid; Clonidine; Electric Stimulation; Epinephrine; Homeostasis; Hypothalamus; Isoproterenol; Male; Potassium Chloride; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Sulpiride; Yohimbine | 1985 |
Beta adrenoceptor modulation of the generation of murine cytotoxic T lymphocytes in vitro.
Topics: Adrenergic alpha-Antagonists; Animals; Atenolol; Butoxamine; Epinephrine; Immunity, Cellular; Isomerism; Isoproterenol; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Norepinephrine; Phentolamine; Propranolol; Receptors, Adrenergic, beta; T-Lymphocytes, Cytotoxic; Terbutaline | 1986 |
Modification of dobutamine- and terbutaline-induced calcium and fluid secretion from rat salivary glands by atenolol and butoxamine.
Topics: Animals; Atenolol; Butoxamine; Calcium; Catecholamines; Dobutamine; Dose-Response Relationship, Drug; Female; Parotid Gland; Propanolamines; Rats; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Saliva; Salivation; Secretory Rate; Submandibular Gland; Terbutaline | 1985 |
Beta adrenergic and muscarinic receptor densities of rat submandibular main duct.
Topics: Animals; Atenolol; Butoxamine; Cell Membrane; Dihydroalprenolol; Female; Quinuclidinyl Benzilate; Rats; Receptors, Adrenergic, beta; Receptors, Muscarinic; Submandibular Gland | 1987 |
Failure of isoprenaline and beta-receptor blocking drugs to modify depressor response and bradycardia induced by electrical stimulation of the anterior hypothalamus of cats.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Blood Pressure; Butoxamine; Cats; Electric Stimulation; Female; Heart Rate; Hypothalamus; Hypothalamus, Anterior; Isoproterenol; Male; Propranolol; Time Factors | 1980 |
An attempt to characterize the beta-adrenoceptor subtype mediating tail skin temperature response of rats to acute administration of isoproterenol.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Butoxamine; Dose-Response Relationship, Drug; Female; Isoproterenol; Nadolol; Propanolamines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Skin Temperature; Tail | 1983 |
Effect of fenoterol on immunological release of leukotrienes and histamine from human lung in vitro: selective antagonism by beta-adrenoceptor antagonists.
Topics: Adrenergic beta-Antagonists; Atenolol; Butoxamine; Ethanolamines; Fenoterol; Histamine Release; Humans; In Vitro Techniques; Leukotriene E4; Lung; Propranolol; SRS-A | 1983 |
Beta-1 receptor mediation of renin secretion elicited by low-frequency renal nerve stimulation.
Topics: Animals; Atenolol; Blood Pressure; Butoxamine; Dogs; Electric Stimulation; Female; Glomerular Filtration Rate; Kidney; Male; Natriuresis; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, beta; Renin | 1981 |
Adrenaline involvement in the presynaptic beta-adrenoceptor-mediated mechanism of dopamine release from slices of the rat hypothalamus.
Topics: Action Potentials; Albuterol; Animals; Atenolol; Butoxamine; Chromatography, High Pressure Liquid; Dopamine; Epinephrine; Hypothalamus; Isoproterenol; Male; Propanolamines; Propranolol; Rats; Receptors, Adrenergic, beta; Tetrodotoxin | 1984 |
Involvement of beta 3-adrenoceptor in the relaxation response in guinea pig taenia caecum.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Binding, Competitive; Butoxamine; Cecum; Dose-Response Relationship, Drug; Epinephrine; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Microsomes; Muscle Relaxation; Muscle, Smooth; Norepinephrine; Phentolamine; Propanolamines; Radioligand Assay; Receptors, Adrenergic, beta | 1994 |
Participation of alpha 1- and beta 1-adrenoceptors in norepinephrine-induced contraction and relaxation of isolated equine coronary artery in vitro.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-1 Receptor Antagonists; Animals; Atenolol; Butoxamine; Coronary Vessels; Endothelium, Vascular; Female; Horses; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Phentolamine; Propranolol; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta-1; Thromboxane A2; Yohimbine | 1994 |
Antiinflammatory influences of alpha-MSH molecules: central neurogenic and peripheral actions.
Topics: alpha-MSH; Amino Acid Sequence; Animals; Anti-Inflammatory Agents, Non-Steroidal; Atenolol; Atropine; Butoxamine; Cerebral Ventricles; Edema; Female; Injections, Intraventricular; Melanocyte-Stimulating Hormones; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Peptide Fragments; Phentolamine; Receptors, Neurotransmitter; Spinal Cord | 1994 |
The regulation of total creatine content in a myoblast cell line.
Topics: Animals; Atenolol; Bucladesine; Butoxamine; Cell Line; Clenbuterol; Creatine; Energy Metabolism; Insulin; Insulin-Like Growth Factor I; Isoproterenol; Labetalol; Methoxamine; Mice; Muscle, Skeletal; Norepinephrine; Phentolamine; Propranolol; Sodium; Triiodothyronine | 1996 |
Peripheral beta-adrenoreceptors and stress-induced hypercholesterolemia in rats.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Butoxamine; Electroshock; Fatty Acids, Nonesterified; Hypercholesterolemia; Male; Propranolol; Rats; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Stress, Psychological | 1996 |
Contraction and relaxation responses of femoral artery and aorta to norepinephrine in young rats.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Aorta; Atenolol; Butoxamine; Femoral Artery; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Propranolol; Rats; Rats, Wistar | 1996 |
Inhibition of peripheral NF-kappaB activation by central action of alpha-melanocyte-stimulating hormone.
Topics: Acute Disease; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; alpha-MSH; Animals; Atenolol; Atropine; Blotting, Western; Brain Chemistry; Butoxamine; DNA-Binding Proteins; Encephalitis; I-kappa B Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Muscarinic Antagonists; Neural Pathways; NF-kappa B; NF-KappaB Inhibitor alpha; Phentolamine; Propranolol; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Receptors, Corticotropin; Receptors, Melanocortin; Spinal Cord; Tumor Necrosis Factor-alpha | 1999 |
Pharmacological analysis of atypical beta-adrenoceptors in the guinea pig gastric fundus using the beta(3)-adrenoceptor antagonist bupranolol.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Atenolol; Bupranolol; Butoxamine; Catecholamines; Dose-Response Relationship, Drug; Epinephrine; Ethanolamines; Gastric Fundus; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Norepinephrine; Propanolamines; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-3 | 1999 |
Characterization of [3H]CGP 12177 binding to beta-adrenergic receptors in intact eel hepatocytes.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Alprenolol; Anguilla; Animals; Atenolol; Binding Sites; Binding, Competitive; Butoxamine; Cell Count; Colforsin; Cyclic AMP; Epinephrine; Glucose; Guanosine 5'-O-(3-Thiotriphosphate); Hepatocytes; Kinetics; Propanolamines; Propranolol; Receptors, Adrenergic, beta; Tritium | 2001 |
Structure-activity relationship studies of (+/-)-terbutaline and (+/-)-fenoterol on beta3-adrenoceptors in the guinea pig gastric fundus.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Atenolol; Bupranolol; Butoxamine; Fenoterol; Gastric Fundus; Guinea Pigs; Male; Muscle Relaxation; Receptors, Adrenergic, beta-3; Structure-Activity Relationship; Terbutaline | 2001 |
The beta3-adrenoceptor-mediated relaxation induced by dopamine in guinea pig taenia caecum.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Atenolol; Benzazepines; Butoxamine; Cecum; Dopamine; Dopamine Antagonists; Guinea Pigs; Haloperidol; Male; Muscle Relaxation; Phentolamine; Prazosin; Propranolol; Receptors, Adrenergic, beta-3; Yohimbine | 2003 |
Effect of Larrea divaricata Cav. extract and nordihydroguaiaretic acid upon peroxidase secretion in rat submandibulary glands.
Topics: 3,3'-Diaminobenzidine; Animals; Argentina; Aspirin; Atenolol; Butoxamine; Dinoprostone; Dobutamine; Dose-Response Relationship, Drug; Drug Synergism; Female; Forecasting; Larrea; Masoprocol; Peroxidase; Plant Extracts; Plant Leaves; Prazosin; Propranolol; Rats; Rats, Wistar; Submandibular Gland; Water | 2004 |
Nebivolol increases arterial distensibility in vivo.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Benzopyrans; Blood Pressure; Butoxamine; Drug Evaluation, Preclinical; Enzyme Inhibitors; Ethanolamines; Hindlimb; Iliac Artery; Infusions, Intra-Arterial; Nebivolol; Nitric Oxide; Nitric Oxide Synthase; Nitroglycerin; omega-N-Methylarginine; Receptors, Adrenergic, beta-2; Sheep; Vascular Resistance | 2004 |
Atenolol or butoxamine injection at the lateral septum doesn't inhibit male sexual behavior in rats.
Topics: Animals; Atenolol; Butoxamine; Drug Combinations; Female; Injections, Intraventricular; Male; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Septal Nuclei; Sexual Behavior, Animal | 2005 |
Pharmacological characterization of the beta-adrenoceptor that mediates the relaxant response to noradrenaline in guinea-pig tracheal smooth muscle.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Antagonists; Adrenergic Uptake Inhibitors; Albuterol; Animals; Atenolol; Bupranolol; Butoxamine; Desipramine; Desoxycorticosterone; Dose-Response Relationship, Drug; Female; Guinea Pigs; Histamine; Imidazoles; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Norepinephrine; Phentolamine; Propanolamines; Propranolol; Receptors, Adrenergic, beta-1; Trachea | 2007 |
Restoration of neutrophil immunocompetence after cardiopulmonary bypass by beta-adrenergic blockers.
Topics: Adrenergic beta-Antagonists; Atenolol; Butoxamine; Catecholamines; Coronary Artery Bypass; Cytokines; Epinephrine; Flow Cytometry; Free Radicals; Humans; Immunocompetence; Isoquinolines; N-Formylmethionine Leucyl-Phenylalanine; Naphthyridines; Neutrophils; Pindolol; Prazosin | 2010 |
Possible involvement of β₁ receptors in various emetogen-induced increases in salivary amylase activity in rats.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Agonists; Amylases; Animals; Antiemetics; Apomorphine; Atenolol; Butoxamine; Cisplatin; Depression, Chemical; Emetics; Isoproterenol; Lithium Chloride; Male; Metoclopramide; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic, beta-1; Saliva | 2011 |
Acquisition of Pavlovian fear conditioning using β-adrenoceptor activation of the dorsal premammillary nucleus as an unconditioned stimulus to mimic live predator-threat exposure.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Agonists; Analysis of Variance; Animals; Atenolol; Butoxamine; Conditioning, Classical; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fear; Isoproterenol; Male; Mammillary Bodies; Microinjections; Neural Pathways; Odorants; Periaqueductal Gray; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Valine | 2011 |
Does selective beta-1 blockade provide bone marrow protection after trauma/hemorrhagic shock?
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Bone Marrow; Butoxamine; Contusions; Disease Models, Animal; Hematopoietic Stem Cells; Lung Injury; Male; Propanolamines; Protective Agents; Rats; Rats, Sprague-Dawley; Shock, Hemorrhagic | 2012 |
Functional effects of β3-adrenoceptor on pacemaker activity in interstitial cells of Cajal from the mouse colon.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aminophenols; Animals; Atenolol; Benzophenanthridines; Biological Clocks; Butoxamine; Calcium; Colon; Dose-Response Relationship, Drug; Ethanolamines; Female; Interstitial Cells of Cajal; Intestine, Small; Male; Membrane Potentials; Mice; NG-Nitroarginine Methyl Ester; Norepinephrine; Potassium Channel Blockers; Propanolamines; Propranolol; Receptors, Adrenergic, beta-3; Sulfonamides | 2015 |
Effect of selective β-adrenoceptor blockade and surgical resection of the celiac-superior mesenteric ganglion complex on delayed liquid gastric emptying induced by dipyrone, 4-aminoantipyrine, and antipyrine in rats.
Topics: Adrenergic beta-Antagonists; Ampyrone; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Atenolol; Butoxamine; Dipyrone; Dose-Response Relationship, Drug; Ganglia, Sympathetic; Ganglionectomy; Gastric Emptying; Male; Models, Animal; Propanolamines; Rats, Wistar; Receptors, Adrenergic, beta; Sympathetic Nervous System | 2016 |
Suppression of tooth movement-induced sclerostin expression using β-adrenergic receptor blockers.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Bone Morphogenetic Proteins; Bone Remodeling; Bone Resorption; Butoxamine; Genetic Markers; Osteoclasts; Osteocytes; Propranolol; RANK Ligand; Rats; Rats, Inbred SHR; Tooth Movement Techniques | 2020 |