buthionine sulfoximine has been researched along with trypanothione in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Agosin, M; Maya, JD; Morello, A; Opazo, E; Repetto, Y | 1 |
| Chodacka, B; Steenkamp, DJ; Vogt, R; Weldrick, DP | 1 |
| Harmon, MA; Huynh, TT; Huynh, VT; Phillips, MA | 1 |
| Comini, MA; Flohé, L; Guerrero, SA; Haile, S; Lünsdorf, H; Menge, U | 1 |
| Ferreira, J; Maya, JD; Morello, A; Pabón, A; Pavani, M; Pino, L; Repetto, Y; Rodríguez, A | 1 |
| Goyeneche-Patino, DA; Saravia, NG; Valderrama, L; Walker, J | 1 |
| González-Chávez, Z; Mejia-Tlachi, M; Moreno-Sánchez, R; Rodríguez-Zavala, JS; Saavedra, E; Silva, A; Vázquez, C | 1 |
| Encalada, R; González-Chávez, Z; Manning-Cela, R; Márquez-Dueñas, C; Mejia-Tlachi, M; Michels, PAM; Moreno-Sánchez, R; Rodríguez-Enríquez, S; Saavedra, E; Vázquez, C | 1 |
8 other study(ies) available for buthionine sulfoximine and trypanothione
| Article | Year |
|---|---|
Glutathione and trypanothione in several strains of Trypanosoma cruzi: effect of drugs.
Topics: Animals; Antimetabolites; Buthionine Sulfoximine; Cycloheximide; Glutathione; Nifurtimox; Nitroimidazoles; Species Specificity; Spermidine; Trypanocidal Agents; Trypanosoma cruzi | 1996 |
The effect of buthionine sulfoximine on the growth of Leishmania donovani in culture.
Topics: Animals; Buthionine Sulfoximine; Culture Media; Glutathione; Leishmania donovani; Methylhistidines; Oxidation-Reduction; Spermidine; Time Factors | 1999 |
Gene knockdown of gamma-glutamylcysteine synthetase by RNAi in the parasitic protozoa Trypanosoma brucei demonstrates that it is an essential enzyme.
Topics: Animals; Base Sequence; Buthionine Sulfoximine; Cell Death; DNA, Protozoan; Enzyme Inhibitors; Glutamate-Cysteine Ligase; Glutathione; RNA Interference; Spermidine; Sulfhydryl Compounds; Trypanosoma brucei brucei | 2003 |
Validation of Trypanosoma brucei trypanothione synthetase as drug target.
Topics: Amide Synthases; Animals; Antimetabolites, Antineoplastic; Buthionine Sulfoximine; Cell Survival; Down-Regulation; Glutathione; Hydrogen Peroxide; Oxidants; Oxidative Stress; RNA Interference; Spermidine; Suppression, Genetic; Trypanosoma brucei brucei | 2004 |
Effects of buthionine sulfoximine nifurtimox and benznidazole upon trypanothione and metallothionein proteins in Trypanosoma cruzi.
Topics: Animals; Buthionine Sulfoximine; Electrophoresis, Polyacrylamide Gel; Glutathione; Metallothionein; Nifurtimox; Nitroimidazoles; Protozoan Proteins; Spermidine; Time Factors; Trypanocidal Agents; Trypanosoma cruzi | 2004 |
Antimony resistance and trypanothione in experimentally selected and clinical strains of Leishmania panamensis.
Topics: Animals; Antimony; Antiprotozoal Agents; Buthionine Sulfoximine; Drug Resistance; Glutathione; Humans; Leishmania; Leishmaniasis; Parasitic Sensitivity Tests; Spermidine | 2008 |
Buthionine sulfoximine is a multitarget inhibitor of trypanothione synthesis in Trypanosoma cruzi.
Topics: Amide Synthases; Animals; Buthionine Sulfoximine; Enzyme Inhibitors; Glutamate-Cysteine Ligase; Glutathione; Glutathione Synthase; Humans; Kinetics; Metabolic Networks and Pathways; Molecular Docking Simulation; Protozoan Proteins; Recombinant Proteins; Spermidine; Trypanosoma cruzi | 2017 |
Gamma-glutamylcysteine synthetase and tryparedoxin 1 exert high control on the antioxidant system in Trypanosoma cruzi contributing to drug resistance and infectivity.
Topics: Amide Synthases; Antioxidants; Buthionine Sulfoximine; Cell Line; Drug Combinations; Drug Resistance; Fibroblasts; Gene Expression Regulation; Glutamate-Cysteine Ligase; Glutathione; Humans; Hydrogen Peroxide; NADH, NADPH Oxidoreductases; Nitroimidazoles; Oxidation-Reduction; Oxidative Stress; Peroxidases; Protozoan Proteins; Signal Transduction; Spermidine; Thioredoxins; Trypanocidal Agents; Trypanosoma cruzi | 2019 |