buthionine sulfoximine has been researched along with thiazoles in 69 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (23.19) | 18.7374 |
| 1990's | 26 (37.68) | 18.2507 |
| 2000's | 23 (33.33) | 29.6817 |
| 2010's | 4 (5.80) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Morita, I; Murota, S; Ochi, H | 1 |
| Atzori, L; Cotgreave, I; Grafström, RC; Liu, Y | 1 |
| Ito, K; Mizutani, T; Yoshida, K | 1 |
| Ravindranath, V; Shivakumar, BR | 1 |
| Hotta, T; Kawamoto, K; Kiya, K; Kurisu, K; Mikami, T; Nakada, Y; Saito, Y; Uozumi, T; Yamada, K | 1 |
| Ford, JM; Hait, WN; Yang, JM | 1 |
| Belzer, FO; Boudjema, K; Lindell, SL; Southard, JH | 1 |
| Boyd, MR; Ravindranath, V | 1 |
| DeGraff, W; Friedman, N; Mitchell, JB; Russo, A | 1 |
| Albright, N; DeGraff, WG; Mitchell, JB; Phillips, TL; Rajpal, R; Russo, A | 1 |
| Anderson, ME; Bridges, RJ; Meister, A; Underwood, M | 1 |
| Duddy, SK; Hsia, MT | 1 |
| Asai, K; Funaki, C; Hayashi, T; Kuzuya, F; Kuzuya, M; Naito, M | 1 |
| Allen, RG; Farmer, KJ; Newton, RK; Sohal, RS; Toy, PL | 1 |
| Devoto, MA; Puente, J; Sapag-Hagar, M | 1 |
| Carmichael, J; DeGraff, W; Friedman, N; Glatstein, E; Mitchell, JB; Russo, A; Tochner, Z | 1 |
| Fidelus, RK; Ginouves, P; Lawrence, D; Tsan, MF | 1 |
| Fricke, RF; Goon, DJ; Nagasawa, HT; Roberts, JC; Zera, RT | 1 |
| Fidelus, RK; Tsan, MF | 1 |
| Danis, EH; Del Vecchio, PJ; Rosano, CL; Tsan, MF | 1 |
| Mitchell, JB; Russo, A | 2 |
| Meister, A | 1 |
| Friedman, N; McPherson, S; Mitchell, JB; Russo, A | 1 |
| Baruchel, S; Batist, G; Farah, R; Jamali, M; Wang, T | 1 |
| Bohets, HH; D'Haese, PC; De Broe, ME; Dierickx, PJ; Nouwen, EJ; Van der Biest, I; Van Landeghem, GF; Van Thielen, MN | 1 |
| Herzenberg, LA; Raju, PA; Roederer, M | 1 |
| Huxtable, RJ; Yan, CC | 1 |
| Aschner, M; Kimelberg, HK; Lash, LH; Mullaney, KJ; Wagoner, D | 1 |
| Fujiyama, J; Hirayama, K; Yasutake, A | 1 |
| Bloomer, WD; Damodaran, KM; Prezioso, JA; Wang, N | 1 |
| Baker, ER; Baker, H; DeAngelis, B; Frank, O; Hutner, SH; Khalil, M | 1 |
| Blair, SL; Burt, ME; Rose, DM; Sachar, S | 1 |
| Greene, JJ; Hutter, DE; Till, BG | 1 |
| Arstrand, K; Dizdar, N; Kågedal, B; Kullman, A | 1 |
| Aviram, M; Rosenblat, M | 1 |
| Harris, C; Miller, JM; Nuttall, AL; Raphael, Y; Yamasoba, T | 1 |
| Brash, DE; Chu, E; Ju, J; Liu, M; Pelling, JC | 1 |
| Anderson, ME | 1 |
| Batist, G; Carystinos, GD; Chen, X | 1 |
| Averill, DA; Lord-Fontaine, S | 1 |
| Battaglia, A; Canonico, PL; Carfagna, N; Pamparana, F; Post, C; Sortino, MA | 1 |
| Dizdar, N; Kågedal, B; Kullman, A | 1 |
| Flitney, FW; Holmes, SA; Magid, KS; Megson, IL; Pritchard, RJ | 1 |
| Birnboim, HC; Privora, H | 1 |
| Bai, J; Cederbaum, AI; Marí, M | 1 |
| Chang, YC; Chou, MY; Huang, FM; Tai, KW; Yang, LC | 1 |
| Christen, S; Ferriero, DM; Francisco, C; Gregory, G; Manabat, C; Täuber, M; Vexler, ZS; Wong, A | 1 |
| Chang, YC; Chou, MY; Hsieh, YS; Huang, FM; Lii, CK; Tai, KW | 1 |
| Chang, YC; Chou, MY; Tsai, CH | 1 |
| Han, SY; Huh, K; Jeong, TC; Jin, DQ; Kim, HS; Kim, JA; Lee, YS; Park, SH | 1 |
| Aksenov, ND; Efremova, TN; Gamaleĭ, IA; Kirpichnikova, KM | 1 |
| Bryła, J; Drozak, J; Jagielski, AK; Wegrzynowicz, M; Winiarska, K | 1 |
| Agarwal, N; Aoun, P; Simpkins, JW | 1 |
| Akaike, A; Hashino, A; Kaneko, S; Katsuki, H; Kume, T; Osakada, F | 1 |
| Chang, YC; Chen, YJ; Chu, SC; Hsieh, YS; Tsai, CH; Yang, SF | 1 |
| Maezawa, I; Milatovic, D; Montine, KS; Montine, TJ; Nghiem, W; Vaisar, T; Woltjer, RL | 1 |
| Cohen, SD; Dominick, PK; Roberts, JC; Slitt, AM | 1 |
| Aschner, JL; Aschner, M; Shanker, G; Syversen, T | 1 |
| Akaike, A; Izumi, Y; Katsuki, H; Kume, T; Sawada, H; Shimohama, S; Yamamoto, N | 1 |
| Grossi, P; Kanter, Rd; Monaci, S; Monshouwer, M; Turlizzi, E; Vignati, L | 1 |
| Chang, YC; Ho, YC | 1 |
| Augustin, W; Kropf, S; Makarov, P; Schild, L; Wiswedel, I | 1 |
| Hong, H; Ji, ZN; Liu, GQ; Lu, Y | 1 |
| Almazan, G; Hemdan, S | 1 |
| Arai, M; Hikita, E; Hirano, T; Onda, K; Tanaka, S; Toyoda, H; Utsumi, H; Yuan, B | 1 |
| Requejo, R; Tena, M | 1 |
| Suo, YR; Zhang, C; Zhao, YF | 1 |
| Chang, SW; Chen, JH; Lin, CY; Lin, FJ; Ou, HP; Tsai, CW; Wu, CR | 1 |
4 review(s) available for buthionine sulfoximine and thiazoles
| Article | Year |
|---|---|
The roles of intracellular glutathione in antineoplastic chemotherapy.
Topics: Animals; Antineoplastic Agents; Buthionine Sulfoximine; Cell Survival; Glutathione; Humans; In Vitro Techniques; Methionine Sulfoximine; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1986 |
New aspects of glutathione biochemistry and transport--selective alteration of glutathione metabolism.
Topics: Animals; Biological Transport; Buthionine Sulfoximine; gamma-Glutamyltransferase; Glutamate-Cysteine Ligase; Glutathione; Glutathione Synthase; Humans; Metabolism, Inborn Errors; Methionine Sulfoximine; Mice; Neoplasms, Experimental; Pyroglutamate Hydrolase; Radiation-Sensitizing Agents; Rats; Thiazoles | 1984 |
Glutathione: an overview of biosynthesis and modulation.
Topics: Animals; Buthionine Sulfoximine; Dipeptides; Enzyme Inhibitors; Esterification; Glutamate-Cysteine Ligase; Glutathione; Glutathione Synthase; Humans; Kinetics; Oxidative Stress; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1998 |
Potential for selective modulation of glutathione in cancer chemotherapy.
Topics: Animals; Buthionine Sulfoximine; Cell Communication; Drug Resistance; Enzyme Inhibitors; Female; Gap Junctions; Glutamate-Cysteine Ligase; Glutathione; Humans; Mammary Neoplasms, Experimental; Neoplasms; Prodrugs; Pyroglutamate Hydrolase; Pyrrolidonecarboxylic Acid; Rats; Thiazoles; Thiazolidines | 1998 |
65 other study(ies) available for buthionine sulfoximine and thiazoles
| Article | Year |
|---|---|
Roles of glutathione and glutathione peroxidase in the protection against endothelial cell injury induced by 15-hydroperoxyeicosatetraenoic acid.
Topics: Animals; Antioxidants; Azoles; Buthionine Sulfoximine; Carotid Arteries; Cattle; Cells, Cultured; Endothelium, Vascular; Glutathione; Glutathione Peroxidase; Isoindoles; Kinetics; Leukotrienes; Lipid Peroxides; Maleates; Methionine Sulfoximine; Organoselenium Compounds; Oxidation-Reduction; Pyrrolidonecarboxylic Acid; Selenium; Sodium Selenite; Thiazoles; Thiazolidines | 1992 |
The mechanism of Hg2+ toxicity in cultured human oral fibroblasts: the involvement of cellular thiols.
Topics: Buthionine Sulfoximine; Cell Division; Cell Survival; Cells, Cultured; Coloring Agents; Cysteine; Dental Amalgam; Deoxyglucose; Fibroblasts; Glutathione; Humans; Mercury; Methionine Sulfoximine; Mouth; Neutral Red; Sulfhydryl Compounds; Tetrazolium Salts; Thiazoles | 1992 |
Nephrotoxicity of thiazoles structurally related to thiabendazole in mice depleted of glutathione by treatment with buthionine sulfoximine.
Topics: Animals; Benzimidazoles; Buthionine Sulfoximine; Glutathione; Kidney; Methionine Sulfoximine; Methoxsalen; Mice; Mice, Inbred ICR; Organ Size; Piperonyl Butoxide; Thiabendazole; Thiazoles | 1992 |
Selective modulation of glutathione in mouse brain regions and its effect on acrylamide-induced neurotoxicity.
Topics: Acrylamides; Animals; Brain; Buthionine Sulfoximine; Drug Interactions; Female; Glutathione; Glyceraldehyde-3-Phosphate Dehydrogenases; Injections, Spinal; Liver; Maleates; Methionine Sulfoximine; Mice; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1992 |
Glutathione and cellular response of ACNU-resistant rat glioma sublines to drugs and radiation.
Topics: Animals; Buthionine Sulfoximine; Cell Line; Cell Survival; Dose-Response Relationship, Radiation; Doxorubicin; Drug Resistance; Etoposide; Glioma; Glutathione; Kinetics; Methionine Sulfoximine; Nimustine; Pyrrolidonecarboxylic Acid; Rats; Thiazoles; Thiazolidines; Vinblastine | 1991 |
Effect of buthionine sulfoximine on toxicity of verapamil and doxorubicin to multidrug resistant cells and to mice.
Topics: Animals; Buthionine Sulfoximine; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance; Flupenthixol; Glutathione; Methionine Sulfoximine; Mice; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Verapamil | 1991 |
Changes in glutathione concentration in hypothermically perfused dog kidneys.
Topics: Animals; Antimetabolites; Buthionine Sulfoximine; Cold Temperature; Dithionitrobenzoic Acid; Dogs; Glutathione; Glutathione Disulfide; Kidney; Methionine Sulfoximine; Organ Preservation; Osmolar Concentration; Perfusion; Sulfhydryl Compounds; Thiazoles; Thiazolidines; Time Factors; Tissue Distribution | 1991 |
Effect of modulators of glutathione synthesis on the hepatotoxicity of 2-methylfuran.
Topics: Alanine Transaminase; Animals; Antimetabolites; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Cystine; Drug Interactions; Furans; Glutathione; Male; Maleates; Methionine Sulfoximine; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines | 1991 |
Selective modulation of glutathione levels in human normal versus tumor cells and subsequent differential response to chemotherapy drugs.
Topics: Antineoplastic Agents; Bleomycin; Buthionine Sulfoximine; Cell Survival; Cells, Cultured; Cisplatin; Glutathione; Humans; Lung; Lung Neoplasms; Melphalan; Methionine Sulfoximine; Neoplasms; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Zinostatin | 1986 |
Modification of SR 2508 sensitization in hypoxic V79 cells by manipulation of glutathione levels.
Topics: Animals; Buthionine Sulfoximine; Cell Line; Cell Survival; Cricetinae; Etanidazole; Glutathione; Methionine Sulfoximine; Nitroimidazoles; Oxygen; Pyrrolidonecarboxylic Acid; Radiation-Sensitizing Agents; Thiazoles; Thiazolidines | 1989 |
Glutathione metabolism at the blood-cerebrospinal fluid barrier.
Topics: Animals; Antimetabolites; Biological Transport; Blood-Brain Barrier; Buthionine Sulfoximine; Choroid Plexus; Cysteine; Dipeptides; gamma-Glutamyltransferase; Glutathione; Isoxazoles; Male; Methionine Sulfoximine; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines | 1989 |
Alteration of precocene II-induced hepatotoxicity by modulation of hepatic glutathione levels.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Benzopyrans; Buthionine Sulfoximine; Glutathione; Insecticides; Liver; Male; Methionine Sulfoximine; Plants; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Reference Values; Thiazoles; Thiazolidines | 1989 |
Protective role of intracellular glutathione against oxidized low density lipoprotein in cultured endothelial cells.
Topics: Animals; Antimetabolites; Aorta, Thoracic; Buthionine Sulfoximine; Cattle; Cell Survival; Cells, Cultured; Endothelium, Vascular; Fetus; Glutathione; Kinetics; Lipoproteins, LDL; Methionine Sulfoximine; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1989 |
Effects of experimentally altered glutathione levels on life span, metabolic rate, superoxide dismutase, catalase and inorganic peroxides in the adult housefly, Musca domestica.
Topics: Animals; Buthionine Sulfoximine; Catalase; Energy Metabolism; Glutathione; Houseflies; Kinetics; Life Expectancy; Methionine Sulfoximine; Peroxides; Pyrrolidonecarboxylic Acid; Superoxide Dismutase; Thiazoles; Thiazolidines | 1985 |
Modulation of gamma-glutamyl cycle and glutathione levels in rat mammary gland explants.
Topics: Amidohydrolases; Animals; Buthionine Sulfoximine; Culture Techniques; Female; gamma-Glutamyltransferase; Glutamate-Cysteine Ligase; Glutathione; Mammary Glands, Animal; Methionine Sulfoximine; Peptide Synthases; Pyroglutamate Hydrolase; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines | 1986 |
Modulation of intracellular glutathione concentrations alters lymphocyte activation and proliferation.
Topics: Acridine Orange; Animals; Buthionine Sulfoximine; Cell Cycle; Concanavalin A; Flow Cytometry; Glutathione; Lymphocyte Activation; Lymphocytes; Mercaptoethanol; Methionine Sulfoximine; Mice; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Thymidine | 1987 |
Prodrugs of L-cysteine as protective agents against acetaminophen-induced hepatotoxicity. 2-(Polyhydroxyalkyl)- and 2-(polyacetoxyalkyl)thiazolidine-4(R)-carboxylic acids.
Topics: Acetaminophen; Animals; Buthionine Sulfoximine; Cysteine; Drug Therapy; Glutathione; Liver; Methionine Sulfoximine; Mice; Prodrugs; Rats; Structure-Activity Relationship; Thiazoles; Thiazolidines | 1987 |
Enhancement of intracellular glutathione promotes lymphocyte activation by mitogen.
Topics: Animals; Buthionine Sulfoximine; Glutathione; Lymphocyte Activation; Lymphocytes; Mercaptoethanol; Methionine Sulfoximine; Mice; Mice, Inbred C57BL; Mitogens; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1986 |
Enhancement of intracellular glutathione protects endothelial cells against oxidant damage.
Topics: Animals; Buthionine Sulfoximine; Cattle; Endothelium; Glucose Oxidase; Glutathione; Hydrogen Peroxide; Methionine Sulfoximine; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1985 |
Potentiation and protection of doxorubicin cytotoxicity by cellular glutathione modulation.
Topics: Animals; Buthionine Sulfoximine; Cell Line; Cell Survival; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Free Radicals; Glutathione; Methionine Sulfoximine; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1985 |
Alteration of bleomycin cytotoxicity by glutathione depletion or elevation.
Topics: Animals; Bleomycin; Buthionine Sulfoximine; Cell Line; Cell Survival; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Glutathione; Hydrogen Peroxide; Methionine Sulfoximine; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Time Factors | 1984 |
Radiation response of Chinese hamster cells after elevation of intracellular glutathione levels.
Topics: Aerobiosis; Animals; Buthionine Sulfoximine; Cell Line; Cell Survival; Cobalt; Cricetinae; Cricetulus; Cysteamine; Dose-Response Relationship, Radiation; Glutathione; Methionine Sulfoximine; Pyrrolidonecarboxylic Acid; Radiation-Protective Agents; Radiation-Sensitizing Agents; Thiazoles; Thiazolidines | 1984 |
In vivo selective modulation of tissue glutathione in a rat mammary carcinoma model.
Topics: Animals; Antimetabolites, Antineoplastic; Bone Marrow; Buthionine Sulfoximine; Drug Synergism; Female; Glutathione; Kidney; Liver; Mammary Neoplasms, Experimental; Methionine Sulfoximine; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred F344; Thiazoles; Thiazolidines; Tumor Cells, Cultured | 1995 |
Cytotoxicity of mercury compounds in LLC-PK1, MDCK and human proximal tubular cells.
Topics: Animals; Buthionine Sulfoximine; Cell Line; Dogs; Drug Interactions; Glutathione; Humans; Kidney; Kidney Tubules, Proximal; LLC-PK1 Cells; Mercury Compounds; Methionine Sulfoximine; Pyrrolidonecarboxylic Acid; Spectrophotometry, Atomic; Swine; Thiazoles; Thiazolidines | 1995 |
Glutathione precursor and antioxidant activities of N-acetylcysteine and oxothiazolidine carboxylate compared in in vitro studies of HIV replication.
Topics: Acetylcysteine; Antimetabolites; Antioxidants; Antiviral Agents; Buthionine Sulfoximine; Cells, Cultured; Free Radical Scavengers; Gene Expression Regulation, Viral; Genes, Reporter; Glutathione; HIV Long Terminal Repeat; HIV-1; Humans; Leukocytes, Mononuclear; Methionine Sulfoximine; Monocytes; Prodrugs; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Tumor Necrosis Factor-alpha; Virus Replication | 1994 |
Relationship between glutathione concentration and metabolism of the pyrrolizidine alkaloid, monocrotaline, in the isolated, perfused liver.
Topics: Analysis of Variance; Animals; Antimetabolites, Antineoplastic; Bile; Buthionine Sulfoximine; Ethylene Chlorohydrin; Glutathione; Liver; Male; Maleates; Methionine Sulfoximine; Monocrotaline; Perfusion; Pyrroles; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidines | 1995 |
Intracellular glutathione (GSH) levels modulate mercuric chloride (MC)- and methylmercuric chloride (MeHgCl)-induced amino acid release from neonatal rat primary astrocytes cultures.
Topics: Animals; Animals, Newborn; Aspartic Acid; Astrocytes; Buthionine Sulfoximine; Cells, Cultured; Glutamate-Cysteine Ligase; Glutathione; Mercuric Chloride; Methionine Sulfoximine; Methylmercury Compounds; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Taurine; Thiazoles; Thiazolidines; Tritium | 1994 |
Mechanism of methylmercury efflux from cultured astrocytes.
Topics: Animals; Astrocytes; Buthionine Sulfoximine; Cells, Cultured; Cysteine; Glutathione; Methionine Sulfoximine; Methylmercury Compounds; Probenecid; Pyrrolidonecarboxylic Acid; Rats; Thiazoles; Thiazolidines | 1994 |
Mechanism(s) regulating inhibition of thymidylate synthase and growth by gamma-L-glutaminyl-4-hydroxy-3-iodobenzene, a novel melanin precursor, in melanogenic melanoma cells.
Topics: Animals; Biotransformation; Buthionine Sulfoximine; Cell Division; Glutamine; Glutathione; GTP Phosphohydrolases; Humans; Melanins; Melanoma; Methionine Sulfoximine; Mice; Monophenol Monooxygenase; Oxidation-Reduction; Phenols; Protein Precursors; Tetrazolium Salts; Thiazoles; Thymidylate Synthase; Tumor Cells, Cultured | 1993 |
Antioxidant survey to assess antagonism to redox stress using a prokaryotic and an eukaryotic system.
Topics: Antioxidants; Buthionine Sulfoximine; Cysteine; Escherichia coli; Eukaryota; Free Radicals; Glutathione; Homocysteine; Methionine Sulfoximine; Oxidative Stress; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Vitamin K; Vitamin K 3 | 1996 |
Oral L-2-oxo-4-thiazolidine reduces bacterial translocation after radiation in the Fischer rat.
Topics: Administration, Oral; Animals; Bacteria; Bacterial Translocation; Body Weight; Buthionine Sulfoximine; Cells, Cultured; Eating; Glutathione; Jejunum; Liver; Lymph Nodes; Mesentery; Pyrrolidonecarboxylic Acid; Radiation-Protective Agents; Rats; Rats, Inbred F344; Thiazoles; Thiazolidines | 1996 |
Redox state changes in density-dependent regulation of proliferation.
Topics: Acetylcysteine; Buthionine Sulfoximine; Cell Division; Cell Line; Contact Inhibition; Fibroblasts; Fibrosarcoma; Glutathione; Humans; Male; Neoplasm Proteins; Oxidation-Reduction; Protein Binding; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Transcription Factors; Tumor Cells, Cultured | 1997 |
Effects on interstitial glutathione, cysteine and 5-S-cysteinyldopa of buthionine sulphoximine in human melanoma transplants.
Topics: Acetylcysteine; Animals; Antimetabolites, Antineoplastic; Buthionine Sulfoximine; Cysteine; Cysteinyldopa; Drug Interactions; Enzyme Inhibitors; Glutathione; Humans; Melanoma; Mice; Mice, Inbred BALB C; Mice, Nude; Microdialysis; Neoplasm Transplantation; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1997 |
Macrophage glutathione content and glutathione peroxidase activity are inversely related to cell-mediated oxidation of LDL: in vitro and in vivo studies.
Topics: Animals; Apolipoproteins E; Arteriosclerosis; Buthionine Sulfoximine; Cell Line; Glutathione; Glutathione Peroxidase; Lipoproteins, LDL; Macrophages; Macrophages, Peritoneal; Mice; Mice, Transgenic; Oxidation-Reduction; Peroxides; Pyrrolidonecarboxylic Acid; Selenium; Superoxides; Thiazoles; Thiazolidines | 1998 |
Role of glutathione in protection against noise-induced hearing loss.
Topics: Animals; Antioxidants; Auditory Threshold; Buthionine Sulfoximine; Chromatography, High Pressure Liquid; Cochlea; Cysteine; Evoked Potentials, Auditory, Brain Stem; Female; Glutathione; Guinea Pigs; Hearing Loss, Noise-Induced; Prodrugs; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1998 |
Antioxidant action via p53-mediated apoptosis.
Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Blotting, Northern; Blotting, Western; Buthionine Sulfoximine; Cells, Cultured; Dimercaprol; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Glutathione; Mice; Oxidation-Reduction; Pyrrolidonecarboxylic Acid; Sulfhydryl Compounds; Thiazoles; Thiazolidines; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Vitamin E | 1998 |
Enhancement of cytotoxicity of hydrogen peroxide by hyperthermia in chinese hamster ovary cells: role of antioxidant defenses.
Topics: Acetylcysteine; Amitrole; Animals; Antioxidants; Buthionine Sulfoximine; Catalase; Cell Survival; CHO Cells; Cricetinae; Enzyme Inhibitors; Glutathione; Hot Temperature; Hydrogen Peroxide; Intracellular Fluid; Mesna; Oxidation-Reduction; Protective Agents; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1999 |
Neuroprotective effects of nicergoline in immortalized neurons.
Topics: Animals; Antioxidants; Benzoquinones; Buthionine Sulfoximine; Cell Death; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Enzyme Inhibitors; Maleates; Neurons; Neuroprotective Agents; Nicergoline; Staurosporine; Tetrazolium Salts; Thiazoles; Ubiquinone; Vitamin E | 1999 |
Comparison of N-acetylcysteine and l-2-oxothiazolidine-4-carboxylate as cysteine deliverers and glutathione precursors in human malignant melanoma transplants in mice.
Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; Cysteine; Cysteinyldopa; Enzyme Inhibitors; Glutathione; Humans; Melanoma; Melanoma, Experimental; Mice; Mice, Nude; Microdialysis; Neoplasm Transplantation; Protein Precursors; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Transplantation, Heterologous; Tumor Cells, Cultured | 2000 |
Selective modifiers of glutathione biosynthesis and 'repriming' of vascular smooth muscle photorelaxation.
Topics: Animals; Antimetabolites; Antioxidants; Buthionine Sulfoximine; Glutathione; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroso Compounds; Photochemistry; Rats; Rats, Wistar; S-Nitrosoglutathione; Tail; Thiazoles | 2000 |
Depletion of intracellular glutathione reduces mutations by nitric oxide-donating drugs.
Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; Cell Survival; Gamma Rays; Glutathione; Hypoxanthine Phosphoribosyltransferase; Mice; Mutagenesis; Mutagens; Nitric Oxide; Nitric Oxide Donors; Nitrites; Nitroglycerin; Nitroprusside; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Tumor Cells, Cultured | 2000 |
Adenovirus-mediated overexpression of catalase in the cytosolic or mitochondrial compartment protects against toxicity caused by glutathione depletion in HepG2 cells expressing CYP2E1.
Topics: Adenoviridae; Apoptosis; Blotting, Western; Buthionine Sulfoximine; Catalase; Cytochrome P-450 CYP2E1; Cytosol; Enzyme Inhibitors; Flow Cytometry; Genetic Vectors; Glutathione; Humans; Lipid Peroxidation; Membrane Potentials; Mitochondria; Oxygen Consumption; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2002 |
Mechanisms of cytotoxicity of nicotine in human periodontal ligament fibroblast cultures in vitro.
Topics: Analysis of Variance; Antioxidants; Buthionine Sulfoximine; Catalase; Cell Culture Techniques; Cell Division; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibroblasts; Free Radical Scavengers; Glutathione; Humans; Nicotine; Nicotinic Agonists; Periodontal Ligament; Protective Agents; Protein Biosynthesis; Proteins; Pyrrolidonecarboxylic Acid; Smoking; Statistics as Topic; Sulfhydryl Compounds; Superoxide Dismutase; Thiazoles; Thiazolidines | 2002 |
Fructose-1,6-bisphosphate preserves intracellular glutathione and protects cortical neurons against oxidative stress.
Topics: Animals; Buthionine Sulfoximine; Carmustine; Cell Hypoxia; Cell Survival; Cells, Cultured; Cerebral Cortex; Enzyme Inhibitors; Free Radicals; Fructosediphosphates; Glutathione; Glutathione Reductase; Intracellular Fluid; Mice; Molsidomine; Neurons; Neuroprotective Agents; Nitric Oxide; Oxidation-Reduction; Oxidative Stress; Tetrazolium Salts; Thiazoles | 2003 |
Induction of c-fos expression by nicotine in human periodontal ligament fibroblasts is related to cellular thiol levels.
Topics: Analysis of Variance; Buthionine Sulfoximine; Cell Culture Techniques; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibroblasts; Gene Expression Regulation; Genes, fos; Glutathione; Humans; Nicotine; Periodontal Ligament; Protein Precursors; Pyrrolidonecarboxylic Acid; RNA, Messenger; Signal Transduction; Smoking; Sulfhydryl Compounds; Thiazoles; Thiazolidines; Time Factors; Transcription, Genetic | 2003 |
The up-regulation of cyclooxygenase-2 expression in human buccal mucosal fibroblasts by arecoline: a possible role in the pathogenesis of oral submucous fibrosis.
Topics: Arecoline; Aspirin; Buthionine Sulfoximine; Cell Culture Techniques; Cholinergic Agonists; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; Epithelial Cells; Fibroblasts; Glutathione; Humans; Immunohistochemistry; Isoenzymes; Matched-Pair Analysis; Membrane Proteins; Mouth Mucosa; Nitrobenzenes; Oral Submucous Fibrosis; Peroxidases; Prostaglandin-Endoperoxide Synthases; Pyrrolidonecarboxylic Acid; Sulfonamides; Thiazoles; Thiazolidines; Transcription, Genetic; Up-Regulation | 2003 |
2,3,7,8-tetrachlorobenzo-p-dioxin inhibits proliferation of SK-N-SH human neuronal cells through decreased production of reactive oxygen species.
Topics: Antimetabolites, Antineoplastic; Buthionine Sulfoximine; Cell Death; Cell Division; Coloring Agents; Dose-Response Relationship, Drug; Glutathione; Humans; Hydrogen Peroxide; Lipid Peroxidation; Neurons; Oxidation-Reduction; Polychlorinated Dibenzodioxins; Reactive Oxygen Species; Superoxide Dismutase; Teratogens; Tetrazolium Salts; Thiazoles; Time Factors; Trypan Blue; Tumor Cells, Cultured | 2002 |
[Effect of agents changing the intracellular level of reactive oxygen species on the cell cycle phase distribution in 3T3 and 3T3SV40 cell lines].
Topics: 3T3 Cells; Acetylcysteine; Animals; Antioxidants; Apoptosis; Buthionine Sulfoximine; Cell Cycle; Cell Line, Transformed; Dose-Response Relationship, Drug; Glutathione; Mice; Pyrrolidonecarboxylic Acid; Reactive Oxygen Species; Thiazoles; Thiazolidines | 2003 |
Relationship between gluconeogenesis and glutathione redox state in rabbit kidney-cortex tubules.
Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; Enzyme Inhibitors; Gluconeogenesis; Glutathione; Intracellular Membranes; Kidney Cortex; Kidney Tubules; Male; Oxidation-Reduction; Pyrrolidonecarboxylic Acid; Rabbits; Thiazoles; Thiazolidines | 2003 |
Role of PPAR-gamma ligands in neuroprotection against glutamate-induced cytotoxicity in retinal ganglion cells.
Topics: Animals; Antioxidants; Buthionine Sulfoximine; Cell Line, Transformed; Cell Survival; Chromans; Cytoprotection; Glutamic Acid; Ligands; Neuroprotective Agents; Prostaglandin D2; Rats; Receptors, Cytoplasmic and Nuclear; Retinal Ganglion Cells; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone | 2003 |
Alpha-tocotrienol provides the most potent neuroprotection among vitamin E analogs on cultured striatal neurons.
Topics: Animals; Antimetabolites; Antioxidants; Apoptosis; Bisbenzimidazole; Buthionine Sulfoximine; Carcinogens; Cell Survival; Cells, Cultured; Chromatography, High Pressure Liquid; Fluorescent Dyes; Hydrogen Peroxide; Immunohistochemistry; In Situ Nick-End Labeling; L-Lactate Dehydrogenase; Neostriatum; Neurons; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Wistar; Staurosporine; Tetrazolium Salts; Thiazoles; Tocotrienols; Vitamin E | 2004 |
Regulation of interleukin-6 expression by arecoline in human buccal mucosal fibroblasts is related to intracellular glutathione levels.
Topics: Areca; Arecoline; Buthionine Sulfoximine; Fibroblasts; Glutathione; Humans; Interleukin-6; Male; Oral Submucous Fibrosis; Polymerase Chain Reaction; Pyrrolidonecarboxylic Acid; RNA, Messenger; Thiazoles; Thiazolidines; Up-Regulation | 2004 |
Role of glutathione in intracellular amyloid-alpha precursor protein/carboxy-terminal fragment aggregation and associated cytotoxicity.
Topics: alpha-Tocopherol; Amyloid beta-Protein Precursor; Analysis of Variance; Antioxidants; Blotting, Western; Buthionine Sulfoximine; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Enzyme Inhibitors; Extracellular Space; F2-Isoprostanes; Gene Expression Regulation, Neoplastic; Glutathione; Humans; Neuroblastoma; Peptide Fragments; Protein Synthesis Inhibitors; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tetracycline; Tetrazolium Salts; Thiazoles; Time Factors; Tocopherols | 2005 |
Effect of ribose cysteine pretreatment on hepatic and renal acetaminophen metabolite formation and glutathione depletion.
Topics: Acetaminophen; Animals; Blood Urea Nitrogen; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Cysteine; Glutathione; In Vitro Techniques; Kidney; Kidney Diseases; L-Iditol 2-Dehydrogenase; Liver; Liver Diseases; Male; Mice; Mice, Inbred Strains; Microsomes, Liver; Prodrugs; Protective Agents; Thiazoles; Thiazolidines | 2005 |
Modulatory effect of glutathione status and antioxidants on methylmercury-induced free radical formation in primary cultures of cerebral astrocytes.
Topics: Animals; Animals, Newborn; Antioxidants; Astrocytes; Buthionine Sulfoximine; Cells, Cultured; Fluorescent Dyes; Free Radical Scavengers; Free Radicals; Glutathione; Indicators and Reagents; Mercury Poisoning, Nervous System; Methylmercury Compounds; Mitochondria; Oxidation-Reduction; Oxidative Stress; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidines | 2005 |
Iron accelerates the conversion of dopamine-oxidized intermediates into melanin and provides protection in SH-SY5Y cells.
Topics: Acetylcysteine; Analysis of Variance; Area Under Curve; Buthionine Sulfoximine; Catalase; Cell Death; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Cystine; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Electrochemistry; Enzyme Inhibitors; Humans; Hydrogen Peroxide; Indolequinones; Iron; Melanins; Models, Biological; Neuroblastoma; Superoxide Dismutase; Tetrazolium Salts; Thiazoles; Time Factors | 2005 |
An in vitro approach to detect metabolite toxicity due to CYP3A4-dependent bioactivation of xenobiotics.
Topics: Adenosine Triphosphate; Albendazole; Amitriptyline; Animals; Buthionine Sulfoximine; Carbamazepine; Cell Culture Techniques; Cell Line, Tumor; Cell Survival; Chromans; Coculture Techniques; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dapsone; Enzyme Activation; Flutamide; Glutathione; Humans; Isoniazid; Microsomes; Ochratoxins; Piperazines; Quinidine; Substrate Specificity; Tamoxifen; Tetrazolium Salts; Thiazoles; Thiazolidinediones; Toxicity Tests; Triazolam; Troglitazone; Xenobiotics | 2005 |
Regulation of nicotine-induced cyclooxygenase-2 protein expression in human gingival fibroblasts.
Topics: Buthionine Sulfoximine; Cells, Cultured; Cyclooxygenase 2; Dose-Response Relationship, Drug; Enzyme Induction; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Flavonoids; Gingiva; Humans; Lactate Dehydrogenases; Nicotine; Phosphorylation; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 2006 |
Consumption of redox energy by glutathione metabolism contributes to hypoxia/ reoxygenation-induced injury in astrocytes.
Topics: Animals; Animals, Newborn; Astrocytes; Buthionine Sulfoximine; Cell Hypoxia; Cells, Cultured; Glutathione; Glycogen; Oxidation-Reduction; Oxygen; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles; Time Factors | 2006 |
Up-regulation of P-glycoprotein expression by glutathione depletion-induced oxidative stress in rat brain microvessel endothelial cells.
Topics: Acetylcysteine; Animals; Animals, Newborn; ATP Binding Cassette Transporter, Subfamily B; Blotting, Western; Brain; Buthionine Sulfoximine; Cell Death; Dose-Response Relationship, Drug; Drug Interactions; Endothelial Cells; Enzyme Inhibitors; Free Radical Scavengers; Glutathione; L-Lactate Dehydrogenase; Oxidative Stress; Rats; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Rhodamine 123; RNA, Messenger; Tetrazolium Salts; Thiazoles; Time Factors; Up-Regulation | 2006 |
Deficient peroxide detoxification underlies the susceptibility of oligodendrocyte progenitors to dopamine toxicity.
Topics: Animals; Animals, Newborn; Antioxidants; Azoles; Blotting, Western; Buthionine Sulfoximine; Cells, Cultured; Dopamine; Glutathione; Heme Oxygenase-1; Iron; Isoindoles; L-Lactate Dehydrogenase; Metalloporphyrins; Oligodendroglia; Organoselenium Compounds; Oxidants; Peroxides; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Stem Cells; Superoxide Dismutase; Superoxides; Tetrazolium Salts; Thiazoles | 2007 |
Effects of inorganic and organic arsenic compounds on growth and apoptosis of human T-lymphoblastoid leukemia cells.
Topics: Acetylcysteine; Apoptosis; Arsenic; Ascorbic Acid; Benzimidazoles; Buthionine Sulfoximine; Caspase 3; Caspase 7; Cell Line, Tumor; Cell Proliferation; Female; Humans; Inhibitory Concentration 50; Leukemia, T-Cell; Leukocytes, Mononuclear; Models, Chemical; Organic Chemicals; T-Lymphocytes; Tetrazolium Salts; Thiazoles | 2011 |
Influence of glutathione chemical effectors in the response of maize to arsenic exposure.
Topics: Arsenates; Arsenic; Arsenites; Biological Transport; Biomass; Buthionine Sulfoximine; Chelating Agents; Enzyme Inhibitors; Glutathione; Glutathione Transferase; Hydroponics; Phytochelatins; Plant Roots; Plant Shoots; Seedlings; Succimer; Sulfhydryl Compounds; Thiazoles; Unithiol; Zea mays | 2012 |
MMPT as a reactive oxygen species generator induces apoptosis via the depletion of intracellular GSH contents in A549 cells.
Topics: Acetylcysteine; Aniline Compounds; Apoptosis; Buthionine Sulfoximine; Cell Line, Tumor; Cell Proliferation; Cell Survival; G2 Phase Cell Cycle Checkpoints; Glutathione; Humans; Intracellular Space; M Phase Cell Cycle Checkpoints; Membrane Potential, Mitochondrial; Reactive Oxygen Species; Thiazoles | 2012 |
Carnosic acid prevents 6-hydroxydopamine-induced cell death in SH-SY5Y cells via mediation of glutathione synthesis.
Topics: Abietanes; Antioxidants; Apoptosis; Buthionine Sulfoximine; Cell Line; Down-Regulation; Glutamate-Cysteine Ligase; Glutathione; Humans; JNK Mitogen-Activated Protein Kinases; NF-E2-Related Factor 2; Oxidopamine; p38 Mitogen-Activated Protein Kinases; Plant Extracts; Reactive Oxygen Species; Signal Transduction; Tetrazolium Salts; Thiazoles | 2012 |