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buthionine sulfoximine and metallothionein

buthionine sulfoximine has been researched along with metallothionein in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19908 (23.53)18.7374
1990's17 (50.00)18.2507
2000's7 (20.59)29.6817
2010's1 (2.94)24.3611
2020's1 (2.94)2.80

Authors

AuthorsStudies
Chan, HM; Cherian, MG; Tabarrok, R; Tamura, Y1
Chan, HM; Cherian, MG1
Armario, A; Garvey, JS; Hidalgo, J1
Cherian, MG; Gallant, KR1
Clapper, JA; Enger, MD; Kang, YJ1
Cerutti, PA; Ochi, T1
Cherian, MG; Suzuki, CA1
Anderson, ME; Meister, A; Singhal, RK1
Ochi, T; Ohsawa, M; Otsuka, F; Takahashi, K1
Ochi, T1
Kuroiwa, Y; Oguro, T; Sasaki, M; Sato, M; Yoshida, T1
Backes, MG; Blanock, K; Emerson, EO; Jani, JP; Rihn, C; Scalamogna, D; Singh, SV; Specht, S; Stemmler, N; Xu, BH1
Osmak, M1
Garcia, A; Gasull, T; Giralt, M; Hernandez, J; Hidalgo, J1
Chin, TA; Templeton, DM1
Imura, N; Naganuma, A; Nakagawa, I; Suzuki, M; Yanagiya, T1
Gong, Q; Hart, BA1
Hochadel, JF; Shimizu, M; Waalkes, MP1
Akiyama, S; Chen, ZS; Furukawa, T; Haraguchi, M; Kondo, T; Mutoh, M; Saijo, N; Sumizawa, T; Tani, A1
Imura, N; Naganuma, A; Nakagawa, I; Suzuki, M1
Andrews, GK; De Lisle, RC; Fu, K; Sarras, MP; Tomita, T1
Kang, YJ; Wu, HY1
Denizeau, F; Haïdara, K; Moffatt, P1
Alken, P; Köhrmann, KU; Marx, C; Rassweiler, J; Schummer, B; Seemann, O; Siegsmund, MJ; Steidler, A; Toktomambetova, L1
Fink-Gremmels, J; Sabater-Vilar, M; Schurz, F1
Jiang, J; Kagan, VE; Pitt, BR; St Croix, CM; Sussman, N; Zhao, Q1
Ferreira, J; Maya, JD; Morello, A; Pabón, A; Pavani, M; Pino, L; Repetto, Y; Rodríguez, A1
Akama, Y; Fukuda, A; Owada, S; Saegusa, Y; Yoshida, M1
Hara, H; Kawase, K; Nagase, H; Satoh, M; Shimazawa, M; Suemori, S; Yamamoto, T1
Carlson, EC; Dong, F; Privratsky, JR; Ren, J; Yang, X1
Gao, F; Guo, R; Ma, H; Ren, J; Zhong, L1
Anan, Y; Miyayama, T; Ogra, Y1
Chan, KM; Ooi, TC; Sharif, R1

Reviews

1 review(s) available for buthionine sulfoximine and metallothionein

ArticleYear
Glutathione and cadmium toxicity.
    Nutrition reviews, 1988, Volume: 46, Issue:8

    Topics: Animals; Buthionine Sulfoximine; Cadmium; Cadmium Poisoning; Glutathione; Humans; Metallothionein; Methionine Sulfoximine; Mice

1988

Other Studies

33 other study(ies) available for buthionine sulfoximine and metallothionein

ArticleYear
The relative importance of glutathione and metallothionein on protection of hepatotoxicity of menadione in rats.
    Chemico-biological interactions, 1992, Sep-28, Volume: 84, Issue:2

    Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; Calcium; Chemical and Drug Induced Liver Injury; Cytosol; Glutathione; In Vitro Techniques; L-Lactate Dehydrogenase; Liver; Male; Metallothionein; Methionine Sulfoximine; Phenobarbital; Potassium; Rats; Rats, Sprague-Dawley; Sulfates; Vitamin K; Zinc; Zinc Sulfate

1992
Protective roles of metallothionein and glutathione in hepatotoxicity of cadmium.
    Toxicology, 1992, Volume: 72, Issue:3

    Topics: Animals; Buthionine Sulfoximine; Cadmium; Drug Interactions; Enzyme Induction; Glutathione; In Vitro Techniques; Liver; Male; Metallothionein; Methionine Sulfoximine; Rats; Rats, Inbred Strains; Sulfates; Zinc; Zinc Sulfate

1992
On the metallothionein, glutathione and cysteine relationship in rat liver.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:2

    Topics: Animals; Body Weight; Buthionine Sulfoximine; Cysteine; Glutathione; Isoxazoles; Liver; Male; Metallothionein; Methionine Sulfoximine; Organ Size; Rats; Rats, Inbred Strains; Starvation; Stress, Physiological; Zinc

1990
Metabolic changes in glutathione and metallothionein in newborn rat liver.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 249, Issue:2

    Topics: Alkynes; Animals; Animals, Newborn; Buthionine Sulfoximine; Cysteine; Female; gamma-Glutamyltransferase; Glutathione; Glycine; Liver; Metallothionein; Methionine Sulfoximine; Pargyline; Pregnancy; Rats; Zinc

1989
Enhanced cadmium cytotoxicity in A549 cells with reduced glutathione levels is due to neither enhanced cadmium accumulation nor reduced metallothionein synthesis.
    Cell biology and toxicology, 1989, Volume: 5, Issue:3

    Topics: Buthionine Sulfoximine; Cadmium; Glutathione; Humans; Lung Neoplasms; Maleates; Metallothionein; Methionine Sulfoximine; Sulfur Radioisotopes; Tumor Cells, Cultured

1989
Differential effects of glutathione depletion and metallothionein induction on the induction of DNA single-strand breaks and cytotoxicity by tert-butyl hydroperoxide in cultured mammalian cells.
    Chemico-biological interactions, 1989, Volume: 72, Issue:3

    Topics: Animals; Buthionine Sulfoximine; Cell Line; Cell Survival; Cricetinae; Cricetulus; DNA Damage; DNA Repair; DNA Replication; DNA, Single-Stranded; Glutathione; Kinetics; Lung; Metallothionein; Methionine Sulfoximine; Peroxides; tert-Butylhydroperoxide

1989
Renal glutathione depletion and nephrotoxicity of cadmium-metallothionein in rats.
    Toxicology and applied pharmacology, 1989, Volume: 98, Issue:3

    Topics: Animals; Buthionine Sulfoximine; Cadmium; Glutathione; Kidney; Male; Metallothionein; Methionine Sulfoximine; Rats; Rats, Inbred Strains

1989
Glutathione, a first line of defense against cadmium toxicity.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1987, Volume: 1, Issue:3

    Topics: 1-Propanol; Animals; Buthionine Sulfoximine; Cadmium; Cadmium Chloride; Chemical and Drug Induced Liver Injury; Glutamate-Cysteine Ligase; Glutathione; Male; Metallothionein; Methionine Sulfoximine; Mice

1987
Glutathione and metallothioneins as cellular defense against cadmium toxicity in cultured Chinese hamster cells.
    Chemico-biological interactions, 1988, Volume: 65, Issue:1

    Topics: Acetates; Acetic Acid; Animals; Buthionine Sulfoximine; Cadmium; Cell Line; Cricetinae; Cricetulus; Fibroblasts; Glutathione; Lung; Male; Metallothionein; Methionine Sulfoximine

1988
Effects of glutathione depletion and induction of metallothioneins on the cytotoxicity of an organic hydroperoxide in cultured mammalian cells.
    Toxicology, 1988, Volume: 50, Issue:3

    Topics: Animals; Buthionine Sulfoximine; Butylated Hydroxytoluene; Cell Division; Cells, Cultured; Cricetinae; Deferoxamine; DNA Damage; Glutathione; Lipid Peroxides; Male; Metallothionein; Methionine Sulfoximine; Peroxides; tert-Butylhydroperoxide

1988
Induction of metallothionein synthesis by glutathione depletion after trans- and cis-stilbene oxide administration in rats.
    Chemico-biological interactions, 1995, Oct-20, Volume: 98, Issue:1

    Topics: Animals; Buthionine Sulfoximine; Decanoic Acids; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluorocarbons; Glutathione; Glutathione Transferase; Kinetics; Liver; Male; Metallothionein; Methionine Sulfoximine; Rats; Rats, Wistar; RNA, Messenger; Stereoisomerism; Stilbenes; Zinc

1995
Mechanism of cross-resistance to cisplatin in a mitomycin C-resistant human bladder cancer cell line.
    International journal of cancer, 1995, May-04, Volume: 61, Issue:3

    Topics: Antimetabolites, Antineoplastic; Biological Transport; Buthionine Sulfoximine; Cadmium; Cadmium Chloride; Carboplatin; Cell Line; Cell Survival; Chlorides; Cisplatin; Drug Resistance; Gene Expression; Glutathione; Glutathione Transferase; Humans; Isoenzymes; Kinetics; Metallothionein; Methionine Sulfoximine; Mitomycin; RNA, Messenger; Tumor Cells, Cultured; Urinary Bladder Neoplasms

1995
Multifactorial molecular mechanisms are involved in resistance of preirradiated human cervix carcinoma cells to cis-dichlorodiammineplatinum (II) and vincristine.
    Neoplasma, 1993, Volume: 40, Issue:2

    Topics: Antimetabolites, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Buthionine Sulfoximine; Cadmium; Cadmium Chloride; Carrier Proteins; Chlorides; Cisplatin; Dose-Response Relationship, Drug; Drug Resistance; Ethacrynic Acid; Female; Gamma Rays; Glutathione; Glutathione Transferase; HeLa Cells; Humans; Membrane Glycoproteins; Metallothionein; Methionine Sulfoximine; Ultraviolet Rays; Uterine Cervical Neoplasms; Verapamil; Vincristine

1993
Effect of stress, adrenalectomy and changes in glutathione metabolism on rat kidney metallothionein content: comparison with liver metallothionein.
    Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 1993,Autumn, Volume: 6, Issue:3

    Topics: Adrenal Glands; Adrenalectomy; Animals; Buthionine Sulfoximine; Corticosterone; Glutathione; Isoxazoles; Kidney; Liver; Male; Metallothionein; Methionine Sulfoximine; Organ Specificity; Rats; Rats, Sprague-Dawley; Restraint, Physical; Starvation; Stress, Physiological

1993
Protective elevations of glutathione and metallothionein in cadmium-exposed mesangial cells.
    Toxicology, 1993, Jan-29, Volume: 77, Issue:1-2

    Topics: Animals; Antimetabolites; Buthionine Sulfoximine; Cadmium; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Glomerular Mesangium; Glutathione; Male; Metallothionein; Methionine Sulfoximine; Rats; Rats, Wistar; Thymidine; Tritium; Zinc

1993
Effect of glutathione depletion on metallothionein synthesis induced by paraquat in mice.
    The Tohoku journal of experimental medicine, 1995, Volume: 177, Issue:3

    Topics: Animals; Antimetabolites; Blotting, Northern; Buthionine Sulfoximine; Cadmium; Chlorides; Chromatography, Gel; Chromatography, Ion Exchange; Dactinomycin; Dexamethasone; Glucocorticoids; Glutathione; Herbicides; Kidney; Liver; Male; Maleates; Metallothionein; Mice; Mice, Inbred ICR; Paraquat; Protein Synthesis Inhibitors; Zinc Compounds

1995
Effect of thiols on cadmium-induced expression of metallothionein and other oxidant stress genes in rat lung epithelial cells.
    Toxicology, 1997, May-16, Volume: 119, Issue:3

    Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; Cadmium Chloride; Carcinogens; Cell Death; Cell Line; DNA Probes; Dose-Response Relationship, Drug; Epithelium; Gene Expression; Glutathione; Glutathione Transferase; Heme Oxygenase (Decyclizing); Kinetics; Lung; Metallothionein; Oxidoreductases; Rats; RNA, Messenger

1997
Effects of glutathione depletion on cadmium-induced metallothionein synthesis, cytotoxicity, and proto-oncogene expression in cultured rat myoblasts.
    Journal of toxicology and environmental health, 1997, Aug-29, Volume: 51, Issue:6

    Topics: Animals; Buthionine Sulfoximine; Cadmium Chloride; Carcinogens; Cell Survival; Cells, Cultured; Enzyme Inhibitors; Glutathione; Metallothionein; Muscle, Skeletal; Proto-Oncogene Proteins c-jun; Proto-Oncogene Proteins c-myc; Rats

1997
An active efflux system for heavy metals in cisplatin-resistant human KB carcinoma cells.
    Experimental cell research, 1998, May-01, Volume: 240, Issue:2

    Topics: Anion Transport Proteins; ATP-Binding Cassette Transporters; Buthionine Sulfoximine; Carrier Proteins; Cisplatin; DNA, Complementary; Drug Resistance, Multiple; Glutamate-Cysteine Ligase; Glutathione; Humans; Metallothionein; Metals, Heavy; Multidrug Resistance-Associated Proteins; Nitrofurantoin; Tartrates; Transfection; Tumor Cells, Cultured

1998
Involvement of oxidative stress in paraquat-induced metallothionein synthesis under glutathione depletion.
    Free radical biology & medicine, 1998, Volume: 24, Issue:9

    Topics: Animals; Buthionine Sulfoximine; Glutathione; Injections, Subcutaneous; Liver; Male; Metallothionein; Mice; Mice, Inbred ICR; Oxidative Stress; Paraquat; Reactive Oxygen Species; Tumor Cells, Cultured

1998
Metallothionein protects against cerulein-induced acute pancreatitis: analysis using transgenic mice.
    Pancreas, 1998, Volume: 17, Issue:3

    Topics: Acute Disease; Amylases; Animals; Buthionine Sulfoximine; Ceruletide; Glutathione; Heme Oxygenase (Decyclizing); Male; Metallothionein; Mice; Mice, Knockout; Mice, Transgenic; Pancreas; Pancreatitis; Proto-Oncogene Proteins c-fos; RNA, Messenger

1998
Inhibition of buthionine sulfoximine-enhanced doxorubicin toxicity in metallothionein overexpressing transgenic mouse heart.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 287, Issue:2

    Topics: Animals; Antibiotics, Antineoplastic; Antidotes; Buthionine Sulfoximine; Creatine Kinase; Doxorubicin; Glutathione; Heart; Malondialdehyde; Metallothionein; Mice; Mice, Transgenic; Myocardium

1998
Metallothionein induction attenuates the effects of glutathione depletors in rat hepatocytes.
    Toxicological sciences : an official journal of the Society of Toxicology, 1999, Volume: 49, Issue:2

    Topics: Animals; Antidotes; Antioxidants; Buthionine Sulfoximine; Catalase; Cell Survival; Glutathione; Glutathione Peroxidase; Liver; Maleates; Metallothionein; Proteins; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Time Factors; Zinc

1999
Cisplatin-resistant bladder carcinoma cells: enhanced expression of metallothioneins.
    Urological research, 1999, Volume: 27, Issue:3

    Topics: Antineoplastic Agents; Buthionine Sulfoximine; Cadmium; Carcinoma, Transitional Cell; Cell Division; Cisplatin; Doxorubicin; Drug Resistance; Drug Resistance, Multiple; Glutathione; Humans; Metallothionein; Methotrexate; Tumor Cells, Cultured; Urinary Bladder Neoplasms; Vinblastine

1999
Mutagenicity of mercury chloride and mechanisms of cellular defence: the role of metal-binding proteins.
    Mutagenesis, 2000, Volume: 15, Issue:6

    Topics: 3T3 Cells; Animals; Antimetabolites, Antineoplastic; Buthionine Sulfoximine; Cell Nucleus; DNA Damage; Dose-Response Relationship, Drug; Free Radicals; Genes, Reporter; Glutathione; Hydrogen Peroxide; Lac Operon; Mercuric Chloride; Mercury; Metallothionein; Mice; Mutagenicity Tests; Mutagens; Mutation; Oxygen; Plasmids

2000
Contribution of glutathione and metallothioneins to protection against copper toxicity and redox cycling: quantitative analysis using MT+/+ and MT-/- mouse lung fibroblast cells.
    Chemical research in toxicology, 2002, Volume: 15, Issue:8

    Topics: Animals; Buthionine Sulfoximine; Cell Survival; Copper; Fibroblasts; Glutathione; Metallothionein; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidation-Reduction

2002
Effects of buthionine sulfoximine nifurtimox and benznidazole upon trypanothione and metallothionein proteins in Trypanosoma cruzi.
    Biological research, 2004, Volume: 37, Issue:1

    Topics: Animals; Buthionine Sulfoximine; Electrophoresis, Polyacrylamide Gel; Glutathione; Metallothionein; Nifurtimox; Nitroimidazoles; Protozoan Proteins; Spermidine; Time Factors; Trypanocidal Agents; Trypanosoma cruzi

2004
Measurement of radical-scavenging ability in hepatic metallothionein of rat using in vivo electron spin resonance spectroscopy.
    Toxicology, 2005, Sep-15, Volume: 213, Issue:1-2

    Topics: Animals; Buthionine Sulfoximine; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Glutathione; Liver; Male; Metallothionein; Nitrogen Oxides; Rats; Rats, Sprague-Dawley; Spin Labels; Zinc Sulfate

2005
Metallothionein, an endogenous antioxidant, protects against retinal neuron damage in mice.
    Investigative ophthalmology & visual science, 2006, Volume: 47, Issue:9

    Topics: Animals; Antioxidants; Buthionine Sulfoximine; Cell Culture Techniques; Cell Survival; Cholecalciferol; Glutamic Acid; Immunoenzyme Techniques; Injections; Male; Metallothionein; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Oxidative Stress; Retinal Diseases; Retinal Ganglion Cells; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Up-Regulation; Vitreous Body; Zinc Sulfate

2006
Metallothionein alleviates glutathione depletion-induced oxidative cardiomyopathy in murine hearts.
    Critical care medicine, 2008, Volume: 36, Issue:7

    Topics: Animals; Buthionine Sulfoximine; Cardiomyopathies; Enzyme Inhibitors; Glutathione; Glutathione Synthase; Lipid Peroxidation; Male; Metallothionein; Mice; Mice, Transgenic; Myocardial Contraction; Myocytes, Cardiac; Reactive Oxygen Species; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Ultrasonography

2008
Metallothionein alleviates oxidative stress-induced endoplasmic reticulum stress and myocardial dysfunction.
    Journal of molecular and cellular cardiology, 2009, Volume: 47, Issue:2

    Topics: Animals; Apoptosis; Biomarkers; Blotting, Western; Buthionine Sulfoximine; Caspase 3; Endoplasmic Reticulum; Heart; Heart Function Tests; Heart Ventricles; In Vitro Techniques; Metallothionein; Mice; Myocardial Contraction; Oxidative Stress; Perfusion; Reactive Oxygen Species; Stress, Physiological

2009
Effect of glutathione depletion on removal of copper from LEC rat livers by tetrathiomolybdate.
    Journal of inorganic biochemistry, 2010, Volume: 104, Issue:8

    Topics: Animals; Buthionine Sulfoximine; Chelating Agents; Copper; Enzyme Inhibitors; Glutathione; Hepatolenticular Degeneration; Humans; Liver; Male; Metallothionein; Molybdenum; Oxidation-Reduction; Rats; Rats, Inbred LEC; Rats, Wistar; Time Factors

2010
Zinc L-Carnosine Protects CCD-18co Cells from L-Buthionine Sulfoximine-Induced Oxidative Stress via the Induction of Metallothionein and Superoxide Dismutase 1 Expression.
    Biological trace element research, 2020, Volume: 198, Issue:2

    Topics: Buthionine Sulfoximine; Carnosine; Glutathione; Humans; Metallothionein; Organometallic Compounds; Oxidative Stress; Superoxide Dismutase; Superoxide Dismutase-1; Zinc Compounds

2020