Page last updated: 2024-08-22

buthionine sulfoximine and leupeptins

buthionine sulfoximine has been researched along with leupeptins in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (27.27)29.6817
2010's8 (72.73)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Broxterman, HJ; de Jong, MC; Dinkelberg, R; Kool, M; Meloen, RH; Puijk, WC; Scheffer, GL; Scheper, RJ; Schroeijers, AB; Slootstra, JW1
Cederbaum, AI; PĂ©rez, MJ1
Leak, RK; Liou, AK; Zigmond, MJ1
Han, YH; Kim, SH; Kim, SZ; Park, WH1
Han, YH; Park, WH1
Han, YH; Kim, SH; Kim, SZ; Moon, HJ; Park, WH; You, BR1
Horie, T; Ito, K; Kugioka, S; Mitsuki, K; Sekine, S1
Chen, YC; Lee, WR; Shen, SC; Tsai, HH; Yang, LL; Yang, LY1
Leak, RK; Posimo, JM; Titler, AM1
Matsuzawa, S; Reed, JC; Wilkie-Grantham, RP1
Heikkila, JJ; Shirriff, CS1

Other Studies

11 other study(ies) available for buthionine sulfoximine and leupeptins

ArticleYear
Peptide transport by the multidrug resistance protein MRP1.
    Cancer research, 2001, Mar-15, Volume: 61, Issue:6

    Topics: Anti-Bacterial Agents; Antimetabolites, Antineoplastic; ATP-Binding Cassette Transporters; Biological Transport; Buthionine Sulfoximine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; HL-60 Cells; Humans; Leupeptins; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Oligopeptides; Tumor Cells, Cultured; Valinomycin

2001
Proteasome inhibition potentiates CYP2E1-mediated toxicity in HepG2 cells.
    Hepatology (Baltimore, Md.), 2003, Volume: 37, Issue:6

    Topics: Antioxidants; Arachidonic Acid; Buthionine Sulfoximine; Carcinoma, Hepatocellular; Cysteine Endopeptidases; Cytochrome P-450 CYP2E1; Drug Synergism; Endopeptidases; Humans; Iron; Leupeptins; Lipid Peroxides; Liver Neoplasms; Lysosomes; Membrane Potentials; Mitochondria, Liver; Multienzyme Complexes; Proteasome Endopeptidase Complex; Tumor Cells, Cultured; Tyrosine

2003
Adaptation to chronic MG132 reduces oxidative toxicity by a CuZnSOD-dependent mechanism.
    Journal of neurochemistry, 2008, Volume: 106, Issue:2

    Topics: Adaptation, Biological; Adrenergic Agents; Animals; Buthionine Sulfoximine; Catalase; Cell Survival; Cysteine Proteinase Inhibitors; Dopamine; Enzyme Inhibitors; Glutathione; Leupeptins; Oxidative Stress; Oxidopamine; PC12 Cells; Proteasome Endopeptidase Complex; Rats; RNA, Small Interfering; Superoxide Dismutase; Tyrosine 3-Monooxygenase

2008
Reactive oxygen species and glutathione level changes by a proteasome inhibitor, MG132, partially affect calf pulmonary arterial endothelial cell death.
    Drug and chemical toxicology, 2010, Volume: 33, Issue:4

    Topics: Acetylcysteine; Animals; Apoptosis; Buthionine Sulfoximine; Cattle; Cell Culture Techniques; Cell Death; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Endothelial Cells; Endothelium, Vascular; Glutathione; Humans; Leupeptins; Membrane Potential, Mitochondrial; Proteasome Inhibitors; Pulmonary Artery; Reactive Oxygen Species

2010
The changes of reactive oxygen species and glutathione by MG132, a proteasome inhibitor affect As4.1 juxtaglomerular cell growth and death.
    Chemico-biological interactions, 2010, Mar-30, Volume: 184, Issue:3

    Topics: Acetylcysteine; Animals; Apoptosis; Buthionine Sulfoximine; Caspase 3; Caspase 8; Cell Line, Tumor; Ditiocarb; Enzyme Inhibitors; G1 Phase; Glutathione; Juxtaglomerular Apparatus; Leupeptins; Membrane Potential, Mitochondrial; Mice; Poly(ADP-ribose) Polymerases; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species

2010
The effects of N-acetyl cysteine on the MG132 proteasome inhibitor-treated lung cancer cells in relation to cell growth, reactive oxygen species and glutathione.
    International journal of molecular medicine, 2010, Volume: 25, Issue:4

    Topics: Acetylcysteine; Apoptosis; Buthionine Sulfoximine; Cell Line, Tumor; Cell Proliferation; Ditiocarb; Glutathione; Humans; Leupeptins; Lung Neoplasms; Membrane Potential, Mitochondrial; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Reactive Oxygen Species

2010
Sustained intrahepatic glutathione depletion causes proteasomal degradation of multidrug resistance-associated protein 2 in rat liver.
    Biochimica et biophysica acta, 2012, Volume: 1822, Issue:6

    Topics: Animals; Buthionine Sulfoximine; Cholestasis, Intrahepatic; Glutathione; Hepatocytes; Leupeptins; Liver; Liver Failure; Male; Membrane Transport Proteins; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Oxidative Stress; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Rats; Rats, Sprague-Dawley; RNA, Messenger; SUMO-1 Protein; Ubiquitin

2012
Quercetin enhancement of arsenic-induced apoptosis via stimulating ROS-dependent p53 protein ubiquitination in human HaCaT keratinocytes.
    Experimental dermatology, 2012, Volume: 21, Issue:5

    Topics: Animals; Apoptosis; Arsenic; Buthionine Sulfoximine; Cell Line; Cell Survival; Fibroblasts; Humans; Keratinocytes; Leupeptins; Membrane Potential, Mitochondrial; Mice; Models, Animal; NIH 3T3 Cells; Peroxides; Quercetin; Reactive Oxygen Species; Tumor Suppressor Protein p53; Ubiquitination

2012
Astrocyte plasticity revealed by adaptations to severe proteotoxic stress.
    Cell and tissue research, 2013, Volume: 352, Issue:3

    Topics: Adaptation, Physiological; Animals; Astrocytes; Autophagy; Blotting, Western; Buthionine Sulfoximine; Cell Nucleus; Cell Survival; Cells, Cultured; Glial Fibrillary Acidic Protein; Glutathione; Immunohistochemistry; Leupeptins; Lysosomal-Associated Membrane Protein 2; Neuronal Plasticity; Proteins; Rats; Rats, Sprague-Dawley; S100 Calcium Binding Protein beta Subunit; Stress, Physiological

2013
Novel phosphorylation and ubiquitination sites regulate reactive oxygen species-dependent degradation of anti-apoptotic c-FLIP protein.
    The Journal of biological chemistry, 2013, May-03, Volume: 288, Issue:18

    Topics: Antimetabolites; Buthionine Sulfoximine; CASP8 and FADD-Like Apoptosis Regulating Protein; Cell Death; Cysteine Proteinase Inhibitors; Down-Regulation; HEK293 Cells; HeLa Cells; Herbicides; Humans; Leupeptins; Mutation, Missense; Paraquat; Phosphorylation; Protein Processing, Post-Translational; Proteolysis; Reactive Oxygen Species; TNF-Related Apoptosis-Inducing Ligand; Ubiquitination; Vitamin K 3; Vitamins

2013
Characterization of cadmium chloride-induced BiP accumulation in Xenopus laevis A6 kidney epithelial cells.
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2017, Volume: 191

    Topics: Animals; Buthionine Sulfoximine; Cadmium Chloride; Calcimycin; Cell Line; Dose-Response Relationship, Drug; Endoplasmic Reticulum Chaperone BiP; Environmental Pollutants; Epithelial Cells; Glutamate-Cysteine Ligase; Heat-Shock Proteins; Heat-Shock Response; Heme Oxygenase-1; HSP70 Heat-Shock Proteins; Kidney; Leupeptins; Oxidative Stress; Proteasome Inhibitors; Time Factors; Tunicamycin; Unfolded Protein Response; Up-Regulation; Xenopus laevis; Xenopus Proteins

2017