buthionine sulfoximine has been researched along with etoposide in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.00) | 18.7374 |
| 1990's | 9 (45.00) | 18.2507 |
| 2000's | 7 (35.00) | 29.6817 |
| 2010's | 3 (15.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Lafleur, MV; Lankelma, J; Mans, DR; Pinedo, HM; Retèl, J; Schuurhuis, GJ; Treskes, M | 1 |
| Hotta, T; Kawamoto, K; Kiya, K; Kurisu, K; Mikami, T; Nakada, Y; Saito, Y; Uozumi, T; Yamada, K | 1 |
| Larsson, R; Nygren, P | 1 |
| Ardiet, C; Navarro, C; Sapet, C; Tranchand, B | 1 |
| Ciriolo, MR; Coppola, S; Ghibelli, L; Lafavia, E; Maresca, V; Rotilio, G | 1 |
| Cowan, KH; Schneider, E; Sinha, BK; Yamazaki, H | 1 |
| Gantchev, TG; Hunting, DJ | 1 |
| Flavell, RA; Lorico, A; Rappa, G; Sartorelli, AC | 1 |
| Davey, MW; Davey, RA; Grech, KV | 1 |
| Adachi, T; Hara, H; Hirano, K; Sakamoto, H | 1 |
| Benderra, Z; Doglia, SM; Manfait, M; Morjani, H; Trussardi, A; Villa, AM | 1 |
| Aller, P; de Blas, E; Fernández, C; Sancho, P; Troyano, A | 1 |
| Kumazaki, T; Nishiyama, M; Okamoto, R; Sekikawa, T; Takano, H; Tanaka, T; Tanimoto, K; Toyada, M; Ukon, K | 1 |
| Alfaro, PA; Goto, H; Kohn, DB; Pepper, KA; Petersen, D; Reynolds, CP; Yang, B | 1 |
| Inoue, H; Miyashita, T; Takemura, H; Ueda, T; Yoshida, A | 1 |
| De Ciucis, C; Domenicotti, C; Marengo, B; Marinari, UM; Nitti, M; Passalacqua, M; Pronzato, MA; Ricciarelli, R; Zingg, JM | 1 |
| Domenicotti, C; Fenoglio, D; Furfaro, AL; Macay, JR; Marengo, B; Marinari, UM; Nitti, M; Parodi, A; Pronzato, MA; Traverso, N | 1 |
| Colla, R; De Ciucis, C; Domenicotti, C; Fenoglio, D; Furfaro, AL; Izzotti, A; Marengo, B; Passalacqua, M; Pronzato, MA; Pulliero, A; Ravera, S; Ricciarelli, R; Speciale, A; Traverso, N | 1 |
20 other study(ies) available for buthionine sulfoximine and etoposide
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Modulation by D,L-buthionine-S,R-sulphoximine of etoposide cytotoxicity on human non-small cell lung, ovarian and breast carcinoma cell lines.
Topics: Antimetabolites, Antineoplastic; Breast Neoplasms; Buthionine Sulfoximine; Carcinoma, Non-Small-Cell Lung; Cisplatin; Doxorubicin; Drug Synergism; Etoposide; Female; Glutathione; Humans; Lung Neoplasms; Methionine Sulfoximine; Ovarian Neoplasms; Tumor Cells, Cultured; Verapamil | 1992 |
Glutathione and cellular response of ACNU-resistant rat glioma sublines to drugs and radiation.
Topics: Animals; Buthionine Sulfoximine; Cell Line; Cell Survival; Dose-Response Relationship, Radiation; Doxorubicin; Drug Resistance; Etoposide; Glioma; Glutathione; Kinetics; Methionine Sulfoximine; Nimustine; Pyrrolidonecarboxylic Acid; Rats; Thiazoles; Thiazolidines; Vinblastine | 1991 |
Differential in vitro sensitivity of human tumor and normal cells to chemotherapeutic agents and resistance modulators.
Topics: Adenocarcinoma; Antineoplastic Agents; Buthionine Sulfoximine; Cell Division; Cell Line; Cell Survival; Cisplatin; Cyclosporins; Doxorubicin; Drug Screening Assays, Antitumor; Etoposide; Humans; Kidney Neoplasms; Kinetics; Leukemia; Lymphocytes; Methionine Sulfoximine; Neurilemmoma; Tumor Cells, Cultured; Verapamil; Vincristine | 1991 |
[Cellular pharmacokinetics of melphalan alone or in combination on human lymphoma or lymphoblasts].
Topics: Antimetabolites; Blastomeres; Burkitt Lymphoma; Buthionine Sulfoximine; Cell Line; Etoposide; Humans; Lymphocytes; Melphalan; Methionine Sulfoximine; Verapamil | 1989 |
Non-oxidative loss of glutathione in apoptosis via GSH extrusion.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Buthionine Sulfoximine; Cell Line; Cycloheximide; Etoposide; Glutathione; Humans; Hydrogen Peroxide; Kinetics; L-Lactate Dehydrogenase; Methionine Sulfoximine; Oxidation-Reduction; Oxidative Stress; Puromycin | 1995 |
Buthionine sulphoximine-mediated sensitisation of etoposide-resistant human breast cancer MCF7 cells overexpressing the multidrug resistance-associated protein involves increased drug accumulation.
Topics: Antimetabolites, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Buthionine Sulfoximine; Cell Line; Cell Survival; Drug Resistance, Multiple; Etoposide; Female; Glutathione; Humans; Kinetics; Methionine Sulfoximine; Tumor Cells, Cultured; Vincristine | 1995 |
Enhancement of etoposide (VP-16) cytotoxicity by enzymatic and photodynamically induced oxidative stress.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Buthionine Sulfoximine; Cytoplasm; DNA Damage; Drug Synergism; Electron Spin Resonance Spectroscopy; Etoposide; Free Radicals; Glutathione; Humans; Indoles; Leukemia; Organometallic Compounds; Oxidative Stress; Photosensitizing Agents; Tumor Cells, Cultured | 1997 |
Evidence that the multidrug resistance protein (MRP) functions as a co-transporter of glutathione and natural product toxins.
Topics: Animals; Antineoplastic Agents; Arsenites; ATP-Binding Cassette Transporters; Buthionine Sulfoximine; Cell Line; Cell Survival; Clone Cells; Cytotoxins; Drug Resistance, Multiple; Etoposide; Glutathione; Kinetics; Mice; Multidrug Resistance-Associated Proteins; Sodium Compounds; Stem Cells | 1997 |
The relationship between modulation of MDR and glutathione in MRP-overexpressing human leukemia cells.
Topics: Antineoplastic Agents; ATP-Binding Cassette Transporters; Buthionine Sulfoximine; Cell Division; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Gene Expression Regulation, Neoplastic; Genes, MDR; Glutathione; Humans; Leukemia; Multidrug Resistance-Associated Proteins; Tumor Cells, Cultured | 1998 |
Enhancement of glucuronosyl etoposide transport by glutathione in multidrug resistance-associated protein-overexpressing cells.
Topics: ATP-Binding Cassette Transporters; Biological Transport; Buthionine Sulfoximine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Glucuronates; Glutathione; Humans; KB Cells; Leukotriene C4; Multidrug Resistance-Associated Proteins | 1999 |
Regulation of cellular glutathione modulates nuclear accumulation of daunorubicin in human MCF7 cells overexpressing multidrug resistance associated protein.
Topics: Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Transporters; Breast Neoplasms; Buthionine Sulfoximine; Cell Nucleus; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Enzyme Inhibitors; Etoposide; Female; Flow Cytometry; Glutathione; Glutathione Synthase; Humans; Microscopy, Confocal; Multidrug Resistance-Associated Proteins; Reverse Transcriptase Polymerase Chain Reaction; Spectrometry, Fluorescence; Tumor Cells, Cultured | 2000 |
Effect of glutathione depletion on antitumor drug toxicity (apoptosis and necrosis) in U-937 human promonocytic cells. The role of intracellular oxidation.
Topics: Adenosine Triphosphate; Alkylating Agents; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Buthionine Sulfoximine; Camptothecin; Cell Death; Cisplatin; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Doxorubicin; Enzyme Inhibitors; Etoposide; Flow Cytometry; Glutathione; Humans; Hydrogen Peroxide; Hypoxia; Immunoblotting; Melphalan; Membrane Potentials; Mitochondria; Monocytes; Necrosis; Nucleic Acid Synthesis Inhibitors; Oxygen; Radiation-Protective Agents; Reactive Oxygen Species; Spectrometry, Fluorescence; Time Factors; Topoisomerase I Inhibitors; U937 Cells | 2001 |
Unique action determinants of double acting topoisomerase inhibitor, TAS-103.
Topics: Aminoquinolines; Antineoplastic Agents, Phytogenic; Blotting, Northern; Blotting, Western; Buthionine Sulfoximine; Camptothecin; Drug Resistance; Enzyme Inhibitors; Etoposide; Fungal Proteins; Glutamate-Cysteine Ligase; Glutathione; GTP-Binding Proteins; Humans; Indenes; Irinotecan; Mitochondrial Proteins; RNA, Messenger; Saccharomyces cerevisiae Proteins; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 2001 |
Transduction of green fluorescent protein increased oxidative stress and enhanced sensitivity to cytotoxic drugs in neuroblastoma cell lines.
Topics: Antineoplastic Agents; Apoptosis; B7-1 Antigen; Buthionine Sulfoximine; Carboplatin; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Glutathione; Green Fluorescent Proteins; Humans; Lentivirus; Luminescent Proteins; Melphalan; Mutation; Neuroblastoma; Oxidative Stress; Transduction, Genetic; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2003 |
Inhibition of glutathione synthesis overcomes Bcl-2-mediated topoisomerase inhibitor resistance and induces nonapoptotic cell death via mitochondrial-independent pathway.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis Regulatory Proteins; Buthionine Sulfoximine; Camptothecin; Caspase 3; Caspase 7; Caspases; Cell Death; Cell Line, Tumor; DNA Topoisomerases, Type I; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Enzyme Activation; Etoposide; Gene Expression Regulation, Leukemic; Glutathione; Humans; Irinotecan; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Topoisomerase I Inhibitors; Tumor Suppressor Protein p53 | 2006 |
PKCδ sensitizes neuroblastoma cells to L-buthionine-sulfoximine and etoposide inducing reactive oxygen species overproduction and DNA damage.
Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Buthionine Sulfoximine; DNA Damage; Enzyme Activation; Enzyme Inhibitors; Etoposide; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Neuroblastoma; Onium Compounds; Protein Kinase C-delta; Reactive Oxygen Species; RNA, Small Interfering; Transfection; Tumor Cells, Cultured | 2011 |
Resistance of neuroblastoma GI-ME-N cell line to glutathione depletion involves Nrf2 and heme oxygenase-1.
Topics: Antineoplastic Agents, Phytogenic; Buthionine Sulfoximine; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Resistance, Neoplasm; Etoposide; Gene Expression; Gene Knockdown Techniques; Glutamate-Cysteine Ligase; Glutathione; Heme Oxygenase-1; Humans; Neuroblastoma; NF-E2-Related Factor 2; Oxidative Stress; Protoporphyrins; Reactive Nitrogen Species; Reactive Oxygen Species | 2012 |
Glutathione-mediated antioxidant response and aerobic metabolism: two crucial factors involved in determining the multi-drug resistance of high-risk neuroblastoma.
Topics: Acetylcysteine; Antioxidants; Apoptosis; Buthionine Sulfoximine; Catalase; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Cell Survival; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Enzyme Inhibitors; Etoposide; Glutathione; Humans; Hydrogen Peroxide; Lipid Peroxidation; Neuroblastoma; Topoisomerase II Inhibitors; Up-Regulation | 2016 |