buthionine sulfoximine has been researched along with ethacrynic acid in 34 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.94) | 18.7374 |
| 1990's | 18 (52.94) | 18.2507 |
| 2000's | 10 (29.41) | 29.6817 |
| 2010's | 5 (14.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Singh, SV; Xu, BH | 1 |
| Medzihradsky, JL; Wilson, JG | 1 |
| Durán, GE; Lau, DH; Lewis, AD; Sikic, BI | 1 |
| Begleiter, A; Israels, LG; Johnston, JB; Mowat, MR; Yang, WZ | 1 |
| Gescher, A; Harpur, ES; Lazenby, CM; Lee, SJ | 1 |
| Hamilton, TC; O'Dwyer, PJ; Ozols, RF; Tew, KD; Yao, KS | 1 |
| Chen, G; Waxman, DJ | 2 |
| Beketić-Oresković, L; Jaksić, M; Osmak, M | 1 |
| Osmak, M | 1 |
| Gupta, V; Singh, SV; Xu, BH | 1 |
| Canonico, PL; Sortino, MA | 1 |
| Borsellino, N; D'Alessandro, N; Flugy, A | 1 |
| Blask, DE; Wilson, ST; Zalatan, F | 1 |
| Canteras-Jordana, M; Rodriguez-Vicente, J; Vicente-Ortega, V | 1 |
| Hamilton, JW; Maccubbin, AE; Warren, AJ | 1 |
| Dimitriadis, KA; Geromichalos, GD; Kortsaris, AH; Kouretas, D; Papazisis, KT; Sivridis, E; Tsekreli, OK | 1 |
| Klockgether, T; Kovar, KA; Schulz, JB; Seyfried, J; Soldner, F; Wüllner, U | 1 |
| Osmak, M; Vuković, L | 1 |
| Chew, M; Mack, P; Wong, KP; Yang, EB; Zhang, K | 1 |
| Magistretti, PJ; Pellerin, L; Slosman, D; Zerarka, S | 1 |
| Klonowski-Stumpe, H; Lüthen, R; Yu, H | 1 |
| Allen, NJ; Antcliffe, D; Duchen, MR; Keelan, J; Pal, S | 1 |
| Colpaert, EE; Lefebvre, RA; Timmermans, JP | 1 |
| Batist, G; Fotouhi-Ardakani, N; Hamilton, D | 1 |
| Horn, TF; Keilhoff, G; Roychowdhury, S; Wolf, G | 1 |
| Golner, S; Hjelmhaug, J; Lobner, D | 1 |
| Chi, L; Gozal, D; Ke, Y; Liu, R; Luo, C | 1 |
| Costa, G; García-Pascual, A; González-Herreros, M; Triguero, D | 1 |
| Cuccarolo, P; Degan, P; Viaggi, S | 1 |
| Aydinoglu, F; Kıroğlu, OE; Oğülener, N | 1 |
| Bothwell, AL; Dukhande, VV; Kawikova, I; Lai, JC | 1 |
| Elbert, T; Hřebabecký, H; Mertlíková-Kaiserová, H; Nencka, R; Plačková, P; Šála, M | 1 |
| Hoffman, JD; Loo, G; Ward, WM | 1 |
2 review(s) available for buthionine sulfoximine and ethacrynic acid
| Article | Year |
|---|---|
Modulation of glutathione and related enzymes in reversal of resistance to anticancer drugs.
Topics: Animals; Antineoplastic Agents; Buthionine Sulfoximine; CHO Cells; Cricetinae; Drug Resistance; Ethacrynic Acid; Female; gamma-Glutamyltransferase; Gene Expression Regulation, Neoplastic; Glutathione; Glutathione Peroxidase; Glutathione Synthase; Glutathione Transferase; Humans; Inactivation, Metabolic; Male; Methionine Sulfoximine; Neoplasm Proteins; Oxidation-Reduction; Thiotepa; Tumor Cells, Cultured | 1995 |
The glutathione system in alkylator resistance.
Topics: Alkylating Agents; Anticarcinogenic Agents; Buthionine Sulfoximine; Enzyme Inhibitors; Ethacrynic Acid; Glutamate-Cysteine Ligase; Glutathione; Glutathione Synthase; Humans; Neoplasms; Pyrazines; Thiones; Thiophenes | 2002 |
32 other study(ies) available for buthionine sulfoximine and ethacrynic acid
| Article | Year |
|---|---|
Effect of buthionine sulfoximine and ethacrynic acid on cytotoxic activity of mitomycin C analogues BMY 25282 and BMY 25067.
Topics: Animals; Buthionine Sulfoximine; DNA, Neoplasm; Drug Resistance; Drug Screening Assays, Antitumor; Ethacrynic Acid; Glutathione Transferase; Leukemia P388; Methionine Sulfoximine; Mitomycin; Mitomycins; Tumor Stem Cell Assay | 1992 |
Potentiation by thiopurines and sulfhydryl-reactive agents of the inhibition by 3-deazaadenosine of mononuclear phagocytes.
Topics: Animals; Azathioprine; Buthionine Sulfoximine; Cells, Cultured; Cyclohexanones; Drug Synergism; Ethacrynic Acid; Glutathione; Mercaptopurine; Methionine Sulfoximine; Mice; Phagocytes; Phagocytosis; Tubercidin | 1992 |
Sensitization of drug resistant human ovarian cancer cells to cyanomorpholino doxorubicin (MRA-CN) by modulation of glutathione metabolism.
Topics: Antibiotics, Antineoplastic; Buthionine Sulfoximine; Cell Survival; Doxorubicin; Drug Resistance; Ethacrynic Acid; Female; Glutathione; Humans; In Vitro Techniques; Methionine Sulfoximine; Ovarian Neoplasms; Tumor Cells, Cultured | 1992 |
Role of glutathione and glutathione S-transferase in chlorambucil resistance.
Topics: 3T3 Cells; Animals; Antineoplastic Agents; Blotting, Northern; Blotting, Southern; Buthionine Sulfoximine; Cell Survival; Chlorambucil; DNA; Drug Interactions; Drug Resistance; Ethacrynic Acid; Gene Rearrangement; Glutathione; Glutathione Transferase; Isoenzymes; Methionine Sulfoximine; Mice; RNA, Messenger | 1992 |
Glutathione depletion in the guinea pig and its effect on the acute cochlear toxicity of ethacrynic acid.
Topics: Animals; Buthionine Sulfoximine; Cochlea; Cysteine; Ethacrynic Acid; Female; Glutathione; Guinea Pigs; Kidney; Liver; Male; Methionine Sulfoximine; Species Specificity | 1988 |
Identification of glutathione S-transferase as a determinant of 4-hydroperoxycyclophosphamide resistance in human breast cancer cells.
Topics: Aldehyde Dehydrogenase; Aldehydes; Breast Neoplasms; Buthionine Sulfoximine; Cell Line; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Resistance; Ethacrynic Acid; Gene Expression Regulation, Enzymologic; Glutathione Transferase; Humans; Methionine Sulfoximine | 1995 |
Human larynx carcinoma cells resistant to cis-diamminedichloroplatinum(II): mechanisms involved in the resistance.
Topics: Buthionine Sulfoximine; Cadmium; Cadmium Chloride; Cell Cycle; Chlorides; Cisplatin; Clone Cells; Drug Resistance; Ethacrynic Acid; Glutathione; Humans; Laryngeal Neoplasms; Methionine Sulfoximine; Tumor Cells, Cultured | 1994 |
Multifactorial molecular mechanisms are involved in resistance of preirradiated human cervix carcinoma cells to cis-dichlorodiammineplatinum (II) and vincristine.
Topics: Antimetabolites, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Buthionine Sulfoximine; Cadmium; Cadmium Chloride; Carrier Proteins; Chlorides; Cisplatin; Dose-Response Relationship, Drug; Drug Resistance; Ethacrynic Acid; Female; Gamma Rays; Glutathione; Glutathione Transferase; HeLa Cells; Humans; Membrane Glycoproteins; Metallothionein; Methionine Sulfoximine; Ultraviolet Rays; Uterine Cervical Neoplasms; Verapamil; Vincristine | 1993 |
Role of cellular glutathione and glutathione S-transferase in the expression of alkylating agent cytotoxicity in human breast cancer cells.
Topics: Alkylating Agents; Antineoplastic Agents; Breast Neoplasms; Buthionine Sulfoximine; Cell Survival; Ethacrynic Acid; Glutathione; Glutathione Transferase; Humans; Methionine Sulfoximine; Tumor Cells, Cultured | 1994 |
Mitomycin C sensitivity in human bladder cancer cells: possible role of glutathione and glutathione transferase in resistance.
Topics: Antimetabolites, Antineoplastic; Buthionine Sulfoximine; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance; Ethacrynic Acid; Glutathione; Glutathione Transferase; Humans; Isoenzymes; Kinetics; Methionine Sulfoximine; Mitomycin; Tumor Cells, Cultured; Urinary Bladder Neoplasms | 1994 |
Neuroprotective effect of insulin-like growth factor I in immortalized hypothalamic cells.
Topics: Animals; Benzoquinones; Buthionine Sulfoximine; Cell Death; Cell Line, Transformed; Ethacrynic Acid; Hypothalamus; Insulin-Like Growth Factor I; Maleates; Methionine Sulfoximine; Mice; Mice, Transgenic; Neurons; Neuroprotective Agents; Radiation-Protective Agents; Ubiquinone; Vitamin K | 1996 |
TNF-induced apoptosis in multidrug resistant friend erythroleukemia is not influenced by the P-glycoprotein and glutathione status of the cell line.
Topics: Acetylcysteine; Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Buthionine Sulfoximine; Cell Differentiation; Diuretics; Doxorubicin; Drug Resistance, Multiple; Drug Synergism; Enzyme Inhibitors; Ethacrynic Acid; Friend murine leukemia virus; Glutathione; Interferon-gamma; Leukemia, Erythroblastic, Acute; Mice; Recombinant Proteins; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1995 |
Physiological melatonin inhibition of human breast cancer cell growth in vitro: evidence for a glutathione-mediated pathway.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Hormonal; Breast Neoplasms; Buthionine Sulfoximine; Cell Division; Diuretics; Ethacrynic Acid; Female; Glutathione; Humans; Melatonin; Receptors, Estrogen; Tamoxifen; Tumor Cells, Cultured | 1997 |
The effects of different antineoplastic agents and of pretreatment by modulators on three melanoma lines.
Topics: Animals; Anisoles; Antineoplastic Agents; Buthionine Sulfoximine; Dicarboxylic Acids; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Ethacrynic Acid; Humans; In Vitro Techniques; Lomustine; Melanoma, Experimental; Melphalan; Mice; Monophenol Monooxygenase; Nitrosourea Compounds; Organophosphorus Compounds; Tumor Cells, Cultured | 1998 |
Detection of mitomycin C-DNA adducts in vivo by 32P-postlabeling: time course for formation and removal of adducts and biochemical modulation.
Topics: Acetylcysteine; Animals; Biotransformation; Buthionine Sulfoximine; Chick Embryo; Cross-Linking Reagents; Dexamethasone; DNA; DNA Adducts; DNA Damage; DNA Repair; Enzyme Induction; Ethacrynic Acid; Glutathione; Glutethimide; Inactivation, Metabolic; Kidney; Liver; Lung; Mitomycin; Phosphorus Radioisotopes; Polychlorinated Biphenyls; Time Factors | 1998 |
Effects of melatonin on proliferation of cancer cell lines.
Topics: Breast Neoplasms; Buthionine Sulfoximine; Cell Division; Cell Survival; Colonic Neoplasms; DNA Replication; DNA, Neoplasm; Dose-Response Relationship, Drug; Ethacrynic Acid; Female; Glutathione; Humans; Melatonin; Ovarian Neoplasms; Tumor Cells, Cultured; Uterine Cervical Neoplasms | 1998 |
Differential effects of L-buthionine sulfoximine and ethacrynic acid on glutathione levels and mitochondrial function in PC12 cells.
Topics: Animals; Antimetabolites; Buthionine Sulfoximine; Cell Survival; Cytosol; Electron Transport Complex IV; Ethacrynic Acid; Glutathione; Mitochondria; PC12 Cells; Rats; Reactive Oxygen Species; Succinate Cytochrome c Oxidoreductase; Time Factors | 1999 |
Reversal of carboplatin resistance in human laryngeal carcinoma cells.
Topics: Amphotericin B; Antineoplastic Agents; Aphidicolin; Buthionine Sulfoximine; Carboplatin; Cyclosporine; Drug Resistance, Neoplasm; Drug Synergism; Ethacrynic Acid; Humans; Laryngeal Neoplasms; Tumor Cells, Cultured | 1999 |
Modulation of cisplatin cytotoxicity and cisplatin-induced DNA cross-links in HepG2 cells by regulation of glutathione-related mechanisms.
Topics: Biological Transport; Buthionine Sulfoximine; Carcinoma, Hepatocellular; Carrier Proteins; Cisplatin; Cross-Linking Reagents; DNA; DNA Damage; Dose-Response Relationship, Drug; Ethacrynic Acid; Glutathione; Glutathione Transferase; Humans; Hydrolyzable Tannins; Indomethacin; Membrane Transport Proteins; Oxidation-Reduction; Quercetin; Tumor Cells, Cultured | 2001 |
Astrocytes as a predominant cellular site of (99m)Tc-HMPAO retention.
Topics: Animals; Astrocytes; Biological Transport; Buthionine Sulfoximine; Cells, Cultured; Cerebral Cortex; Enzyme Inhibitors; Ethacrynic Acid; Glutathione; Maleates; Mice; Neurons; Radiopharmaceuticals; Technetium Tc 99m Exametazime | 2001 |
Glutathione might exert an important function in caerulein-stimulated amylase release in isolated rat pancreatic acini.
Topics: Amylases; Animals; Buthionine Sulfoximine; Calcium; Cell Survival; Cells, Cultured; Ceruletide; Diamide; Ethacrynic Acid; Glutathione; Pancreas; Rats; Sulfhydryl Reagents | 2002 |
Quantitative imaging of glutathione in hippocampal neurons and glia in culture using monochlorobimane.
Topics: Animals; Animals, Newborn; Buthionine Sulfoximine; Cells, Cultured; Dipeptides; Enzyme Inhibitors; Ethacrynic Acid; Fluoresceins; Fluorescent Dyes; Glutamate-Cysteine Ligase; Glutathione; Glutathione Transferase; Hippocampus; Image Processing, Computer-Assisted; Microscopy, Confocal; Microscopy, Fluorescence; Microscopy, Video; Neuroglia; Neurons; Oxidative Stress; Protein Transport; Pyrazoles; Rats | 2001 |
Influence of antioxidant depletion on nitrergic relaxation in the pig gastric fundus.
Topics: Aminoquinolines; Animals; Benzoates; Buthionine Sulfoximine; Carmustine; Chelating Agents; Ditiocarb; Enzyme Inhibitors; Ethacrynic Acid; Gastric Fundus; Glutathione; Hydroxocobalamin; Imidazoles; Immunohistochemistry; In Vitro Techniques; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Superoxide Dismutase; Swine; Thiolester Hydrolases; Ubiquitin Thiolesterase; Vasodilation | 2002 |
Cytosolic and mitochondrial glutathione in microglial cells are differentially affected by oxidative/nitrosative stress.
Topics: Buthionine Sulfoximine; Cell Culture Techniques; Cytosol; Enzyme Induction; Ethacrynic Acid; Glutathione; Interferon-gamma; Lipopolysaccharides; Microglia; Microscopy, Fluorescence; Mitochondria; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidative Stress; Reactive Oxygen Species; Time Factors | 2003 |
Neurotrophic factor effects on oxidative stress-induced neuronal death.
Topics: Animals; Buthionine Sulfoximine; Cell Death; Cells, Cultured; Cerebral Cortex; Chromans; Citric Acid; Ethacrynic Acid; Ferrous Compounds; Fetus; Fibroblast Growth Factor 2; Free Radical Scavengers; Insulin-Like Growth Factor I; Mice; Nerve Growth Factors; Neuroglia; Neurons; Oxidative Stress | 2003 |
Depletion of reduced glutathione enhances motor neuron degeneration in vitro and in vivo.
Topics: Amyotrophic Lateral Sclerosis; Animals; Apoptosis; Apoptosis Inducing Factor; Biomarkers; Buthionine Sulfoximine; Cell Line; Down-Regulation; Enzyme Inhibitors; Ethacrynic Acid; Glutathione; Mice; Mice, Transgenic; Motor Neurons; Mutation; Nerve Degeneration; Oxidative Stress; Reactive Oxygen Species; Spinal Cord; Superoxide Dismutase; Superoxide Dismutase-1; Transcriptional Activation | 2007 |
Localization and thiol dependancy of endogenous nitro compounds-mediating urethral photo-relaxation.
Topics: Animals; Animals, Newborn; Buthionine Sulfoximine; Citrulline; Electric Stimulation; Endothelium, Vascular; Enzyme Inhibitors; Ethacrynic Acid; Female; Fluoresceins; Fluorescent Dyes; Glutathione; In Vitro Techniques; Light; Microscopy, Fluorescence; Muscle Relaxation; Muscle, Smooth; Nitrergic Neurons; Nitric Oxide; Nitric Oxide Synthase Type I; Photolysis; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; S-Nitrosoglutathione; Sheep; Sulfhydryl Compounds; Thiazolidines; Thiourea; Urethra | 2008 |
New insights into redox response modulation in Fanconi's anemia cells by hydrogen peroxide and glutathione depletors.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Buthionine Sulfoximine; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Ethacrynic Acid; Fanconi Anemia; Flow Cytometry; Glutathione; Humans; Hydrogen Peroxide; Jurkat Cells; Membrane Potential, Mitochondrial; Mitochondria; Oxidants; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Vitamin K 3; Vitamins | 2012 |
The effects of thiol modulators on nitrergic nerve- and S-nitrosothiols-induced relaxation in duodenum.
Topics: Analysis of Variance; Animals; Buthionine Sulfoximine; Cysteine; Diuretics; Dose-Response Relationship, Drug; Duodenum; Ethacrynic Acid; Female; Glutamate-Cysteine Ligase; Glutathione Transferase; Male; Mice; Muscle Relaxation; Nitric Oxide; Nitric Oxide Donors; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione; S-Nitrosothiols; Sulfhydryl Reagents; Sulfobromophthalein; Synaptic Transmission; Vasodilator Agents | 2013 |
Neuroprotection against neuroblastoma cell death induced by depletion of mitochondrial glutathione.
Topics: Apoptosis; Azoles; bcl-2-Associated X Protein; Buthionine Sulfoximine; Cell Line, Tumor; Cell Survival; Coculture Techniques; Cytochromes c; Cytosol; Ethacrynic Acid; Glioblastoma; Glutathione; Humans; Isoindoles; Mitochondria; Neuroblastoma; Neurons; Organoselenium Compounds; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species | 2013 |
Transport mechanisms of a novel antileukemic and antiviral compound 9-norbornyl-6-chloropurine.
Topics: Antineoplastic Agents; ATP-Binding Cassette Transporters; Biological Transport; Buthionine Sulfoximine; Cell Line, Tumor; Cell Membrane Permeability; Cell Survival; Dibenzocycloheptenes; Ethacrynic Acid; Facilitated Diffusion; Gene Expression; Humans; Kinetics; Propionates; Purines; Quinolines; T-Lymphocytes; Tritium | 2015 |
Genotoxic effect of ethacrynic acid and impact of antioxidants.
Topics: Antioxidants; Ascorbic Acid; Buthionine Sulfoximine; Chromans; Cyclin-Dependent Kinase Inhibitor p21; Deferoxamine; DNA Damage; Ethacrynic Acid; Glutathione; HCT116 Cells; Heme Oxygenase-1; Humans; Mutagens; NF-E2-Related Factor 2; Reactive Oxygen Species; RNA, Messenger; Transcription Factor CHOP; Tumor Suppressor Protein p53 | 2015 |