buthionine sulfoximine has been researched along with cysteine in 138 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (15.94) | 18.7374 |
| 1990's | 55 (39.86) | 18.2507 |
| 2000's | 40 (28.99) | 29.6817 |
| 2010's | 18 (13.04) | 24.3611 |
| 2020's | 3 (2.17) | 2.80 |
| Authors | Studies |
|---|---|
| Atzori, L; Cotgreave, I; Grafström, RC; Liu, Y | 1 |
| Aebi, S; Lauterburg, BH | 1 |
| Magnusson, T; Pileblad, E | 1 |
| Enger, MD; Kang, YJ | 1 |
| Falvey, D; Frenkel, GD; MacVicar, C | 1 |
| Boylan, LM; Spallholz, JE; Yan, L; Yee, JA | 1 |
| Hill, L; Lailey, AF; Lawston, IW; Stanton, D; Upshall, DG | 1 |
| Caffrey, PB; Frenkel, GD | 1 |
| Hoffer, LJ; Hum, S; Robitaille, L | 1 |
| Murray, DL; Rathbun, WB | 2 |
| Standeven, AM; Wetterhahn, KE | 1 |
| Djurhuus, R; Mansoor, MA; Svardal, AM; Ueland, PM | 1 |
| Morita, S; Noda, T; Ohmori, M; Shimizu, M; Tsujimoto, Y; Yamada, A; Yamano, T | 1 |
| Armario, A; Garvey, JS; Hidalgo, J | 1 |
| Li, J; Murray, DL; Rathbun, WB | 1 |
| Jacobs, WR; Mandel, LJ; Schnellmann, RG | 1 |
| Brötell, H; Karg, E; Rorsman, H; Rosengren, E | 1 |
| Cherian, MG; Gallant, KR | 1 |
| Anderson, ME; Bridges, RJ; Meister, A; Underwood, M | 1 |
| Nakagawa, K | 1 |
| Hettiaratchi, P; Koch, CJ; Stobbe, CC | 1 |
| Javor, B; Newton, GL | 1 |
| Biscay, P; Guichard, M; Lespinasse, F; Malaise, EP | 1 |
| Gescher, A; Harpur, ES; Lazenby, CM; Lee, SJ | 1 |
| Ishikawa, M; Sasaki, K; Takayanagi, G | 1 |
| Yeung, JH | 1 |
| Calvin, HI; Cohen, G; Slivka, A; Spina, MB | 1 |
| Anderstam, B; Harms-Ringdahl, M | 1 |
| Nakagawa, Y | 1 |
| Fricke, RF; Goon, DJ; Nagasawa, HT; Roberts, JC; Zera, RT | 1 |
| Abe, M; Komuro, C; Nishidai, T; Ono, K; Shibamoto, Y; Shrieve, DC; Takahashi, M; Tsutsui, K | 1 |
| Cordeiro, RF; Savarese, TM | 1 |
| Brodie, AE; Reed, DJ | 1 |
| Griffith, OW | 1 |
| Berggren, M; Dawson, J; Moldéus, P | 1 |
| Birkett, DJ; Drew, R; Miners, JO | 1 |
| Mizutani, T; Nomura, H; Tajima, K; Yamamoto, K | 1 |
| Mitchell, JB; Russo, A | 1 |
| Alexandre, E; Boudjema, K; Chenard, MP; Cinqualbre, J; Imbs, P; Jaeck, D; Nakano, H; Wolf, P | 1 |
| Baas, F; Beijnen, J; Borst, P; Dekker, H; Lankelma, J; Oude Elferink, RP; Paulusma, C; van Tellingen, O; Zaman, GJ | 1 |
| Meister, A | 1 |
| Graham, A; O'Leary, VJ; Stone, D; Wood, JL | 2 |
| Harada, T; Hiraishi, H; Ivey, KJ; Mutoh, H; Ota, S; Razandi, M; Sugimoto, T; Terano, A | 1 |
| Feng, Y; Hatcher, EL; Kang, YJ | 1 |
| Baraban, JM; Murphy, TH; Ratan, RR | 1 |
| Hamazaki, S; Minamiyama, Y; Okada, S; Sotomatsu, A; Toyokuni, S | 1 |
| Kesavan, PC; Singh, SP | 1 |
| Atzori, L; Dypbukt, JM; Grafström, RC; Hybbinette, SS; Moldéus, P | 1 |
| Lee, JH; Naito, M; Tsuruo, T | 1 |
| Fujiyama, J; Hirayama, K; Yasutake, A | 1 |
| Dockery, SP; Harrison, DG; Kurz, MA; Sayegh, HS; Wheatley, RM | 1 |
| Aldershvile, J; Anderson, ME; Boesgaard, S; Loft, S; Meister, A; Poulsen, HE | 1 |
| Asensi, M; Estrela, JM; Garcia-España, A; Pallardó, FV; Vina, J | 1 |
| Chiba, T; Ishii, S; Kikuchi, K; Sato, N; Takahashi, S | 1 |
| Baker, ER; Baker, H; DeAngelis, B; Frank, O; Hutner, SH; Khalil, M | 1 |
| Benson, PJ; Gupta, V; Hu, X; Pinto, T; Singh, S; Xia, H; Zaren, HA | 1 |
| Benathan, M | 2 |
| Benathan, M; Labidi, F | 1 |
| de Matos, DG; Furnus, CC; Martinez, AG; Matkovic, M; Moses, DF | 1 |
| Buè, MC; Ciriolo, MR; De Vito, P; Garaci, E; Incerpi, S; Lafavia, E; Palamara, AT; Rotilio, G | 1 |
| Balasubramanian, KA; Benard, O | 1 |
| Boughattas, N; Filipski, E; Filipski, J; Hecquet, B; Lemaigre, G; Levi, F; Li, XM; Metzger, G | 1 |
| Nwabisi, VC; Nwanze, EA | 1 |
| Dringen, R; Hamprecht, B; Kranich, O; Löschmann, PA | 1 |
| Arstrand, K; Dizdar, N; Kågedal, B; Kullman, A | 1 |
| Carr, AC; Winterbourn, CC | 1 |
| Beijersbergen van Henegouwen, GM; Steenvoorden, DP | 1 |
| Harris, C; Miller, JM; Nuttall, AL; Raphael, Y; Yamasoba, T | 1 |
| Huang, J; Khan, S; O'Brien, PJ | 1 |
| Harris, C; McNutt-Scott, TL | 1 |
| Biaglow, J; Held, K; Horan, AM; Koch, CJ; Manevich, Y; Tuttle, S | 1 |
| Shaikh, ZA; Vu, TT; Zaman, K | 1 |
| Cho, MK; Choi, SH; Kim, HJ; Kim, ND; Kim, SG; Kwak, MK | 1 |
| Benathan, M; Furumura, M; Hearing, VJ; Kobayashi, N; Panizzon, RG; Virador, V | 1 |
| Dizdar, N; Kågedal, B; Kullman, A | 1 |
| Grant, MH; Ning, J | 1 |
| Chen, TS; Lang, CA; Nagasawa, HT; Richie, JP | 1 |
| Hill, PA; Meikle, MC; Tumber, A | 1 |
| Chen, TS; Song, H | 1 |
| Kwon, YH; Stipanuk, MH | 1 |
| Catherwood, MA; McMaster, D; Nally, SM; Powell, LA; Trimble, ER | 1 |
| Brunold, C; Galiba, G; Kocsy, G; Rüegsegger, A; Szalai, G; von Ballmoos, P | 1 |
| Carney, EW; Hansen, JM; Harris, C | 1 |
| Khynriam, D; Prasad, SB | 1 |
| Aw, TY; Fujimoto, K; Iwakiri, R; Noda, T; Rhoads, CA | 1 |
| Hiratake, J; Irie, T; Oda, J; Tokutake, N | 1 |
| Bannai, S; Itoh, K; Kuriyama-Matsumura, K; Maebara, K; Sasaki, H; Sato, H; Sato, K; Tamba, M; Wang, H; Yamamoto, M | 1 |
| Awazuhara, M; Chino, M; Fujiwara, T; Hayashi, H; Kim, H; Kim, SG | 1 |
| Akaike, A; Hashino, A; Kaneko, S; Katsuki, H; Kume, T; Osakada, F | 1 |
| Mansfield, K; Nemelivsky, YV; Rajpurohit, R; Shapiro, IM; Teixeira, CC | 1 |
| Birnboim, HC; Do, SK; Haqqani, AS | 1 |
| Iwabuchi, M; Mino, M; Ogawa, K; Yanagida, M | 1 |
| Dubois, J; Duez, P; Ghanem, G; Kinnaert, E; Morandini, R; Van Houtte, P | 1 |
| Anderson, CL; Go, YM; Jones, DP; Kinkade, JM; Kirlin, WG; Ziegler, TR | 1 |
| Cahoon, RE; Chen, S; Jez, JM | 1 |
| Gross, SS; Hao, G; Xie, L | 1 |
| Nikinmaa, M; Pursiheimo, S; Soitamo, AJ | 1 |
| Dixon, M; Hansen, JM; Harris, C | 1 |
| Barber, DS; Buzescu, R; Chopra, R; Ferrante, RJ; Fox, JH; Hersch, SM; Kazantsev, A; Norflus, F; Singh, B; Swindell, MK; Zucker, B | 1 |
| Horii, I; Kawashima, A; Lu, Y; Zhong, L | 1 |
| Sohal, RS; Toroser, D | 1 |
| Cohen, SD; Dominick, PK; Roberts, JC; Slitt, AM | 1 |
| Gao, Y; Gu, LH; Jones, DP; Levin, MS; Mwangi, S; Rubin, DC; Srinivasan, S; Tian, J; Wang, L; Washizawa, N; Ziegler, TR | 1 |
| Chiu, PY; Ko, KM | 1 |
| Blouet, C; Huneau, JF; Mariotti, F; Mikogami, T; Tome, D | 1 |
| Heuvelmans, S; Hristova, M; van der Vliet, A | 1 |
| Giovannini, C; Grande, S; Guidoni, L; Luciani, AM; Palma, A; Rosi, A; Sapora, O; Viti, V | 1 |
| Doneanu, CE; Niture, SK; Pattabiraman, N; Srivenugopal, KS; Velu, CS | 1 |
| Anderson, CL; Iyer, SS; Jones, DP; Ziegler, TR | 1 |
| Banjac, A; Bannai, S; Bornkamm, GW; Conrad, M; Daniel, PT; Issels, RD; Kölle, P; Perisic, T; Sato, H; Seiler, A; Tschoep, K; Weiss, N | 1 |
| Ariga, T; Hasegawa, I; Hosono, T; Hosono-Fukao, T; Iitsuka, Y; Inada, K; Seki, T; Tanaka, R; Yamada, H | 1 |
| Aoki, R; Numazawa, S; Sakaguchi, H; Taira, T; Yoshida, T | 1 |
| Boise, LH; Cai, Y; Croutch, C; Gutman, D; Lee, KP; Matulis, SM; Morales, AA; Yehiayan, L | 1 |
| Blair, S; Deharo, E; Maya, JD; Pabón, A; Saez, J; Zuluaga, L | 1 |
| Banjac Canak, A; Bannai, S; Bornkamm, GW; Conrad, M; Förster, H; Kölle, P; Kremmer, E; Kuhlencordt, P; Lieberman, MW; Mandal, PK; Perisic, T; Sato, H; Seiler, A; Weiss, N | 1 |
| Castellani, P; Ciriolo, MR; Delfino, L; Lucibello, M; Rubartelli, A; Venè, R | 1 |
| Iyamu, EW; Perdew, HA; Woods, GM | 1 |
| Koffler, BE; Maier, R; Zechmann, B | 1 |
| Hodges, NJ; Kershaw, RM | 1 |
| Csorba, T; Dalmay, T; Húska, D; Kawashima, CG; Kopriva, S; Matthewman, CA | 1 |
| Han, JH; Heo, KJ; Jung, HS; Kang, C; Kim, JS; Lee, JH; Pradhan, T | 1 |
| Aydinoglu, F; Kıroğlu, OE; Oğülener, N | 1 |
| Du, F; Li, X; Liu, Z; Xing, J | 1 |
| Duong, DM; Go, YM; Jones, DP; Liang, Y; Orr, M; Pennell, KD; Roede, JR; Seyfried, NT; Walker, DI | 1 |
| Kumar, A; Sharma, N | 1 |
| Li, CY; Mao, JL; Wang, Z; Xiang, CB; Zhao, YJ | 1 |
| Gu, C; Huang, S; Yang, Y; Yuan, H; Zhang, Y | 1 |
| Hou, Y; Hu, CA; Hu, S; Long, M; Mei, H; Wang, L; Wu, G; Yan, L; Yi, D | 1 |
| Gao, H; Guo, X; Lin, D; Peng, Y; Wang, K; Zheng, J | 1 |
| Cai, QS; Hu, ZB; Li, DJ; Lou, LQ; Shi, GL | 1 |
| Parkin, K; Tocmo, R | 1 |
| Bangash, SAK; Joshi, NC; Leustek, T; Meyer, AJ; Zheng, ZL | 1 |
| Benhar, M; Biswal, S; Engelman, R; Hariri, HA; Knany, A; Wolfenson, H | 1 |
| Bian, Y; Cheng, Z; Ding, H; Gai, S; Lin, J; Liu, B; Liu, S; Yang, P; Yuan, M; Zhu, Y | 1 |
| Hussain, Y; Luqman, S; Meena, A; Rajak, S; Raza, W; Singh, J; Sinha, RA | 1 |
1 review(s) available for buthionine sulfoximine and cysteine
| Article | Year |
|---|---|
Glutathione metabolism.
Topics: Animals; Buthionine Sulfoximine; Cysteine; Enzymes; Glutathione; Methionine Sulfoximine; Models, Biological; Oxidation-Reduction | 1995 |
137 other study(ies) available for buthionine sulfoximine and cysteine
| Article | Year |
|---|---|
The mechanism of Hg2+ toxicity in cultured human oral fibroblasts: the involvement of cellular thiols.
Topics: Buthionine Sulfoximine; Cell Division; Cell Survival; Cells, Cultured; Coloring Agents; Cysteine; Dental Amalgam; Deoxyglucose; Fibroblasts; Glutathione; Humans; Mercury; Methionine Sulfoximine; Mouth; Neutral Red; Sulfhydryl Compounds; Tetrazolium Salts; Thiazoles | 1992 |
Divergent effects of intravenous GSH and cysteine on renal and hepatic GSH.
Topics: Animals; Buthionine Sulfoximine; Cysteine; Dose-Response Relationship, Drug; Glutathione; Injections, Intravenous; Kidney; Kinetics; Liver; Male; Methionine Sulfoximine; Rats; Rats, Inbred Strains | 1992 |
Increase in rat brain glutathione following intracerebroventricular administration of gamma-glutamylcysteine.
Topics: Animals; Brain; Brain Stem; Buthionine Sulfoximine; Corpus Striatum; Cysteine; Dipeptides; Glutathione; Injections, Intraventricular; Methionine Sulfoximine; Rats; Rats, Inbred Strains; Substantia Nigra | 1992 |
Increased glutathione levels in quiescent, serum-stimulated NRK-49F cells are associated not with a response to growth factors but with nutrient repletion.
Topics: Animals; Blood; Buthionine Sulfoximine; Cell Division; Cell Line; Culture Media; Cysteine; DNA; Epidermal Growth Factor; Glutamates; Glutamic Acid; Glutathione; Growth Substances; Interphase; Methionine Sulfoximine | 1991 |
Products of the reaction of selenite with intracellular sulfhydryl compounds.
Topics: Antimetabolites; Autoradiography; Buthionine Sulfoximine; Chromatography, Ion Exchange; Chromatography, Thin Layer; Cysteine; Glutathione; HeLa Cells; Humans; Methionine Sulfoximine; Organoselenium Compounds; Selenious Acid; Selenium; Selenium Compounds; Selenium Radioisotopes; Selenocysteine; Sulfhydryl Compounds; Sulfides | 1991 |
Effect of selenium compounds and thiols on human mammary tumor cells.
Topics: Aged; Antimetabolites; Breast Neoplasms; Buthionine Sulfoximine; Cell Survival; Cysteine; Female; Glutathione; Glutathione Peroxidase; Humans; Mercaptoethanol; Methionine Sulfoximine; Organoselenium Compounds; Selenic Acid; Selenious Acid; Selenium; Selenium Compounds; Selenocysteine; Selenomethionine; Sodium Selenite; Sulfhydryl Compounds; Trypan Blue; Tumor Cells, Cultured | 1991 |
Protection by cysteine esters against chemically induced pulmonary oedema.
Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; Chromatography, High Pressure Liquid; Cysteine; Cystine; DNA; Female; Fluorocarbons; Glutathione; Liver; Lung; Methionine Sulfoximine; Perfusion; Pulmonary Edema; Rats; Sulfhydryl Compounds; Time Factors | 1991 |
Inhibition of cell colony formation by selenite: involvement of glutathione.
Topics: Buthionine Sulfoximine; Cell Division; Cell Survival; Cysteine; Dose-Response Relationship, Drug; Glutathione; HeLa Cells; Humans; In Vitro Techniques; Methionine Sulfoximine; Selenious Acid; Selenium; Selenocysteine; Sulfhydryl Compounds | 1991 |
Plasma glutathione turnover in the rat: effect of fasting and buthionine sulfoximine.
Topics: Animals; Antimetabolites; Buthionine Sulfoximine; Chromatography, High Pressure Liquid; Cysteine; Erythrocytes; Fasting; Glutathione; Hemolysis; In Vitro Techniques; Indicators and Reagents; Liver; Male; Methionine Sulfoximine; Rats; Rats, Inbred Strains; Spectrometry, Fluorescence; Sulfur Radioisotopes | 1991 |
Age-related cysteine uptake as rate-limiting in glutathione synthesis and glutathione half-life in the cultured human lens.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Buthionine Sulfoximine; Child; Child, Preschool; Chromatography, High Pressure Liquid; Cysteine; Glutathione; Half-Life; Humans; Infant; Infant, Newborn; Lens, Crystalline; Methionine Sulfoximine; Middle Aged | 1991 |
Conditions for maximizing and inhibiting synthesis of glutathione in cultured rat lenses: an application of HPLC with radioisotope detection.
Topics: Animals; Buthionine Sulfoximine; Chromatography, High Pressure Liquid; Culture Techniques; Cysteine; Glutamate-Cysteine Ligase; Glutathione; Lens, Crystalline; Male; Methionine Sulfoximine; Methods; Rats; Rats, Inbred Strains; Sulfhydryl Compounds; Sulfur Radioisotopes | 1990 |
Tissue-specific changes in glutathione and cysteine after buthionine sulfoximine treatment of rats and the potential for artifacts in thiol levels resulting from tissue preparation.
Topics: Animals; Antimetabolites; Buthionine Sulfoximine; Chromatography, High Pressure Liquid; Cysteine; Dose-Response Relationship, Drug; Glutathione; Injections, Intraperitoneal; Kidney; Liver; Male; Methionine Sulfoximine; Rats; Rats, Inbred Strains; Spectrophotometry; Sulfhydryl Compounds; Time Factors | 1991 |
Modulation of glutathione content and the effect on methionine auxotrophy and cellular distribution of homocysteine and cysteine in mouse cell lines.
Topics: Animals; Antimetabolites; Buthionine Sulfoximine; Cell Division; Cell Line; Culture Media; Cystamine; Cysteamine; Cysteine; Fibroblasts; Glutathione; Homocysteine; Intracellular Fluid; Leukemia, Experimental; Methionine; Methionine Sulfoximine; Mice | 1991 |
Hepatotoxicity of geniposide in rats.
Topics: Administration, Oral; Alanine Transaminase; Animals; Aspartate Aminotransferases; Bilirubin; Buthionine Sulfoximine; Chloramphenicol; Cysteine; Injections, Intraperitoneal; Iridoid Glycosides; Iridoids; Liver; Male; Methionine Sulfoximine; Molecular Structure; Pyrans; Rats; Rats, Inbred Strains; Sulfhydryl Compounds | 1990 |
On the metallothionein, glutathione and cysteine relationship in rat liver.
Topics: Animals; Body Weight; Buthionine Sulfoximine; Cysteine; Glutathione; Isoxazoles; Liver; Male; Metallothionein; Methionine Sulfoximine; Organ Size; Rats; Rats, Inbred Strains; Starvation; Stress, Physiological; Zinc | 1990 |
Cysteine and glutathione metabolism in organ-cultured rat corneas.
Topics: Animals; Buthionine Sulfoximine; Chromatography, High Pressure Liquid; Cornea; Cysteine; Glutathione; Half-Life; Male; Mercaptoethanol; Methionine Sulfoximine; Organ Culture Techniques; Oxygen Consumption; Rats; Rats, Inbred Strains | 1990 |
Intracellular glutathione in the protection from anoxic injury in renal proximal tubules.
Topics: Adenosine Triphosphate; Animals; Buthionine Sulfoximine; Cysteine; Female; Glutathione; Glycine; In Vitro Techniques; Kidney Tubules, Proximal; L-Lactate Dehydrogenase; Methionine Sulfoximine; Oxygen; Oxygen Consumption; Potassium; Rabbits | 1990 |
Modulation of glutathione level in cultured human melanoma cells.
Topics: Antimetabolites; Buthionine Sulfoximine; Cell Line; Cell Survival; Cysteine; Glutathione; Humans; Melanoma; Methionine Sulfoximine; Tumor Cells, Cultured; Vitamin K | 1989 |
Metabolic changes in glutathione and metallothionein in newborn rat liver.
Topics: Alkynes; Animals; Animals, Newborn; Buthionine Sulfoximine; Cysteine; Female; gamma-Glutamyltransferase; Glutathione; Glycine; Liver; Metallothionein; Methionine Sulfoximine; Pargyline; Pregnancy; Rats; Zinc | 1989 |
Glutathione metabolism at the blood-cerebrospinal fluid barrier.
Topics: Animals; Antimetabolites; Biological Transport; Blood-Brain Barrier; Buthionine Sulfoximine; Choroid Plexus; Cysteine; Dipeptides; gamma-Glutamyltransferase; Glutathione; Isoxazoles; Male; Methionine Sulfoximine; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines | 1989 |
Hepatic glutathione metabolism in mice acutely treated with lead acetate.
Topics: Amino Acids, Sulfur; Animals; Antimetabolites; Buthionine Sulfoximine; Cysteine; Glutamate-Cysteine Ligase; Glutathione; Half-Life; Injections, Intraperitoneal; Liver; Male; Methionine; Methionine Sulfoximine; Mice; Organometallic Compounds | 1989 |
Combined radiation-protective and radiation-sensitizing agents. IV: Measurement of intracellular protector concentrations.
Topics: Animals; Ascorbic Acid; Buthionine Sulfoximine; Cell Line; Coenzyme A; Cysteine; Glutathione; Methionine Sulfoximine; Misonidazole; Radiation-Protective Agents; Radiation-Sensitizing Agents | 1989 |
gamma-Glutamylcysteine and thiosulfate are the major low-molecular-weight thiols in halobacteria.
Topics: Buthionine Sulfoximine; Chromatography, High Pressure Liquid; Cysteine; Dipeptides; Glutamate-Cysteine Ligase; Glutathione; Halobacterium; Methionine Sulfoximine; Thiosulfates | 1985 |
SR-2508 plus buthionine sulfoximine or SR-2508 alone: effects on the radiation response and the glutathione content of a human tumor xenograft.
Topics: Buthionine Sulfoximine; Cell Survival; Cysteine; Etanidazole; Glutathione; Humans; Methionine Sulfoximine; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents | 1987 |
Glutathione depletion in the guinea pig and its effect on the acute cochlear toxicity of ethacrynic acid.
Topics: Animals; Buthionine Sulfoximine; Cochlea; Cysteine; Ethacrynic Acid; Female; Glutathione; Guinea Pigs; Kidney; Liver; Male; Methionine Sulfoximine; Species Specificity | 1988 |
Effect of buthionine sulfoximine, an inhibitor of glutathione biosynthesis, on the selenium-induced lethality in mice.
Topics: Animals; Buthionine Sulfoximine; Cysteine; Drug Interactions; Glutathione; Liver; Male; Methionine Sulfoximine; Mice; Selenium | 1988 |
Effect of sulphydryl drugs on paracetamol-induced hepatotoxicity in mice.
Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Animals; Antimetabolites; Blood Proteins; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Cysteine; Glutathione; Liver; Male; Methionine Sulfoximine; Mice; Mice, Inbred ICR; Sulfhydryl Compounds | 1988 |
Depletion of brain glutathione in preweanling mice by L-buthionine sulfoximine.
Topics: Aging; Animals; Antimetabolites; Brain; Buthionine Sulfoximine; Cerebellum; Chromatography, High Pressure Liquid; Cysteine; Glutathione; Liver; Male; Methionine Sulfoximine; Mice; Spinal Cord; Weaning | 1988 |
Relationship between cellular glutathione and hyperthermic toxicity in mammary carcinoma in mice.
Topics: Animals; Buthionine Sulfoximine; Chromatography, High Pressure Liquid; Cysteine; Female; Glutathione; Hyperthermia, Induced; Male; Mammary Neoplasms, Experimental; Methionine Sulfoximine; Mice; Mice, Inbred CBA; Neoplasm Transplantation; Sulfhydryl Compounds | 1986 |
Effects of buthionine sulfoximine and cysteine on the hepatotoxicity of butylated hydroxytoluene in rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Buthionine Sulfoximine; Butylated Hydroxytoluene; Chemical and Drug Induced Liver Injury; Cysteine; Drug Interactions; Glutathione; Lethal Dose 50; Liver Diseases; Male; Methionine Sulfoximine; Rats; Rats, Inbred F344 | 1987 |
Prodrugs of L-cysteine as protective agents against acetaminophen-induced hepatotoxicity. 2-(Polyhydroxyalkyl)- and 2-(polyacetoxyalkyl)thiazolidine-4(R)-carboxylic acids.
Topics: Acetaminophen; Animals; Buthionine Sulfoximine; Cysteine; Drug Therapy; Glutathione; Liver; Methionine Sulfoximine; Mice; Prodrugs; Rats; Structure-Activity Relationship; Thiazoles; Thiazolidines | 1987 |
Combined effect of buthionine sulfoximine and cyclophosphamide upon murine tumours and bone marrow.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Buthionine Sulfoximine; Cell Survival; Colony-Forming Units Assay; Cyclophosphamide; Cysteine; Glutathione; Lung Neoplasms; Male; Methionine Sulfoximine; Mice; Mice, Inbred C3H | 1986 |
Role of glutathione depletion in the mechanism of action of N-methylformamide and N,N-dimethylformamide in a cultured human colon carcinoma cell line.
Topics: Buthionine Sulfoximine; Cell Cycle; Cell Line; Cisplatin; Colonic Neoplasms; Cysteine; Dimethylformamide; Dose-Response Relationship, Drug; Formamides; Glutathione; Humans; Methionine Sulfoximine; Solvents | 1986 |
Buthionine sulfoximine inhibition of cystine uptake and glutathione biosynthesis in human lung carcinoma cells.
Topics: Buthionine Sulfoximine; Cell Line; Cysteine; Cystine; Glutathione; Humans; Lung Neoplasms; Methionine Sulfoximine; Sulfur Radioisotopes | 1985 |
Glutathione turnover in human erythrocytes. Inhibition by buthionine sulfoximine and incorporation of glycine by exchange.
Topics: Buthionine Sulfoximine; Cysteine; Erythrocytes; Glutamates; Glutamic Acid; Glutathione; Glycine; Humans; Kinetics; Methionine Sulfoximine | 1981 |
Glutathione biosynthesis in the isolated perfused rat lung: utilization of extracellular glutathione.
Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; Cysteine; gamma-Glutamyltransferase; Glutamate-Cysteine Ligase; Glutamates; Glutathione; In Vitro Techniques; Lung; Male; Methionine Sulfoximine; Perfusion; Rats; Rats, Inbred Strains | 1984 |
Mechanism of action of paracetamol protective agents in mice in vivo.
Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Animals; Buthionine Sulfoximine; Cysteamine; Cysteine; Glutathione; Liver; Male; Methionine; Methionine Sulfoximine; Mice; Mice, Inbred C3H | 1984 |
Modification of butylated hydroxytoluene-induced pulmonary toxicity in mice by diethyl maleate, buthionine sulfoximine, and cysteine.
Topics: Animals; Body Weight; Buthionine Sulfoximine; Butylated Hydroxytoluene; Cysteine; Drug Synergism; Glutathione; Liver; Lung; Male; Maleates; Methionine Sulfoximine; Mice; Organ Size | 1984 |
Thiols, thiol depletion, and thermosensitivity.
Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; Cell Survival; Cells, Cultured; Cricetinae; Cysteine; Glutathione; Heat-Shock Proteins; Hot Temperature; Maleates; Methionine Sulfoximine; Oxidation-Reduction; Oxygen Consumption; Protein Biosynthesis; Sulfhydryl Compounds; Time Factors | 1983 |
Protective effects of N-acetylcysteine on hypothermic ischemia-reperfusion injury of rat liver.
Topics: Acetylcysteine; Acid Phosphatase; Alanine Transaminase; Animals; Aspartate Aminotransferases; Buthionine Sulfoximine; Cold Temperature; Cysteine; Glutathione; L-Lactate Dehydrogenase; Liver; Male; Methionine Sulfoximine; Oxidation-Reduction; Rats; Rats, Wistar; Reperfusion Injury | 1995 |
Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated protein.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Arsenites; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Buthionine Sulfoximine; Carcinoma, Non-Small-Cell Lung; Cell Division; Cysteine; Drug Resistance, Multiple; Glutathione; Humans; Kinetics; Lung Neoplasms; Methionine Sulfoximine; Multidrug Resistance-Associated Proteins; Recombinant Proteins; Transfection; Tumor Cells, Cultured | 1995 |
Human (THP-1) macrophages oxidize LDL by a thiol-dependent mechanism.
Topics: Buthionine Sulfoximine; Copper; Cysteine; Cystine; Glutathione; Humans; Lipoproteins, LDL; Macrophages; Methionine Sulfoximine; Oxidation-Reduction; Tumor Cells, Cultured | 1994 |
Protection of cultured rat gastric cells against oxidant-induced damage by exogenous glutathione.
Topics: Animals; Buthionine Sulfoximine; Cells, Cultured; Chromium Radioisotopes; Cysteine; Dose-Response Relationship, Drug; Female; gamma-Glutamyltransferase; Glucose; Glucose Oxidase; Glutamate-Cysteine Ligase; Glutathione; Hydrogen Peroxide; Isoxazoles; Male; Methionine Sulfoximine; Protein Precursors; Rats; Rats, Sprague-Dawley; Resting Phase, Cell Cycle; Stomach | 1994 |
Glutathione stimulates A549 cell proliferation in glutamine-deficient culture: the effect of glutamate supplementation.
Topics: Buthionine Sulfoximine; Cell Division; Cysteine; gamma-Glutamyltransferase; Glutamates; Glutamine; Glutathione; Humans; In Vitro Techniques; Methionine Sulfoximine; Tumor Cells, Cultured | 1994 |
Macromolecular synthesis inhibitors prevent oxidative stress-induced apoptosis in embryonic cortical neurons by shunting cysteine from protein synthesis to glutathione.
Topics: Acetylcysteine; Animals; Apoptosis; Buthionine Sulfoximine; Cells, Cultured; Cerebral Cortex; Cycloheximide; Cysteine; Glutamates; Glutathione; Homocysteine; Macromolecular Substances; Methionine Sulfoximine; Neurons; Oxidants; Protein Biosynthesis; Proteins; Rats | 1994 |
Glutathione cycle dependency of ferric nitrilotriacetate-induced lipid peroxidation in mouse proximal renal tubules.
Topics: Aging; Animals; Buthionine Sulfoximine; Cysteine; Fatty Acids; Fatty Acids, Unsaturated; Female; Ferric Compounds; gamma-Glutamyltransferase; Glutathione; Glutathione Synthase; Kidney Cortex; Kidney Medulla; Kidney Tubules, Proximal; Lipid Peroxidation; Male; Methionine Sulfoximine; Mice; Nitrilotriacetic Acid; Sex Characteristics; Thiobarbiturates | 1993 |
Post-irradiation modification of O2, N2, and N2O-mediated damage in dry barley seeds by glutathione and cysteine: probable radiation chemical events.
Topics: Buthionine Sulfoximine; Cobalt Radioisotopes; Cysteine; Gamma Rays; Glutathione; Hordeum; Methionine Sulfoximine; Nitrogen; Nitrous Oxide; Oxygen; Radiation-Protective Agents; Seeds; Water | 1993 |
Modifications of cellular thiols during growth and squamous differentiation of cultured human bronchial epithelial cells.
Topics: Antimetabolites; Bronchi; Buthionine Sulfoximine; Calcium; Cell Differentiation; Cell Division; Cells, Cultured; Cysteine; Cystine; Epithelial Cells; Epithelium; Glutathione; Humans; Maleates; Methionine Sulfoximine; Oxidation-Reduction; Serum Albumin, Bovine; Sulfhydryl Compounds; Transforming Growth Factor beta | 1994 |
Nonenzymatic reductive activation of 7-N-((2-([2-(gamma-L-glutamylamino)ethyl]dithio)ethyl))mitomycin C by thiol molecules: a novel mitomycin C derivative effective on mitomycin C-resistant tumor cells.
Topics: Buthionine Sulfoximine; Colonic Neoplasms; Cysteine; Cytochrome P-450 Enzyme System; DNA, Neoplasm; Drug Interactions; Drug Resistance; Glutathione; Humans; Methionine Sulfoximine; Mitomycin; Mitomycins; Oxidation-Reduction; Sulfhydryl Compounds; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1994 |
Mechanism of methylmercury efflux from cultured astrocytes.
Topics: Animals; Astrocytes; Buthionine Sulfoximine; Cells, Cultured; Cysteine; Glutathione; Methionine Sulfoximine; Methylmercury Compounds; Probenecid; Pyrrolidonecarboxylic Acid; Rats; Thiazoles; Thiazolidines | 1994 |
Interactions of nitroglycerin and sulfhydryl-donating compounds in coronary microvessels.
Topics: Animals; Blood Vessels; Buffers; Buthionine Sulfoximine; Coronary Circulation; Cysteine; Dogs; Drug Interactions; Female; Glutathione; Male; Methionine Sulfoximine; Microcirculation; Nitric Oxide; Nitroglycerin; Oxygen; Sulfhydryl Compounds; Vasodilation | 1994 |
Acute effects of nitroglycerin depend on both plasma and intracellular sulfhydryl compound levels in vivo. Effect of agents with different sulfhydryl-modulating properties.
Topics: Animals; Aorta; Buthionine Sulfoximine; Cysteine; Female; Glutathione; Intracellular Membranes; Methionine Sulfoximine; Nitroglycerin; Rats; Rats, Wistar; Sulfhydryl Compounds; Time Factors; Vena Cava, Superior | 1993 |
Effect of nonprotein thiols on protein synthesis in isolated rat hepatocytes.
Topics: Amino Acids; Aminooxyacetic Acid; Animals; Antimetabolites; Buthionine Sulfoximine; Carbon Radioisotopes; Cells, Cultured; Cysteine; Kinetics; Liver; Maleates; Methionine; Methionine Sulfoximine; Protein Biosynthesis; Rats; Rats, Wistar; Sulfhydryl Compounds | 1996 |
Fas-mediated apoptosis is modulated by intracellular glutathione in human T cells.
Topics: Acetylcysteine; Apoptosis; Buthionine Sulfoximine; Culture Media, Conditioned; Cycloheximide; Cysteine; Cytotoxicity, Immunologic; fas Receptor; Glutathione; Humans; Immunity, Innate; Intracellular Fluid; Killer Cells, Lymphokine-Activated; Leukemia, T-Cell; Lymphocyte Activation; Methionine Sulfoximine; T-Lymphocytes; Tumor Cells, Cultured | 1996 |
Antioxidant survey to assess antagonism to redox stress using a prokaryotic and an eukaryotic system.
Topics: Antioxidants; Buthionine Sulfoximine; Cysteine; Escherichia coli; Eukaryota; Free Radicals; Glutathione; Homocysteine; Methionine Sulfoximine; Oxidative Stress; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Vitamin K; Vitamin K 3 | 1996 |
Lack of a role of glutathione in cellular nonenzymatic activation of BMS-181174, a novel analogue of mitomycin C.
Topics: Antineoplastic Agents, Alkylating; Biotransformation; Buthionine Sulfoximine; Cysteine; Enzyme Inhibitors; Glutamate-Cysteine Ligase; Glutathione; Humans; Methionine Sulfoximine; Mitomycin; Mitomycins; Tumor Cells, Cultured; Urinary Bladder Neoplasms | 1996 |
Modulation of 5-S-cysteinyldopa formation by tyrosinase activity and intracellular thiols in human melanoma cells.
Topics: Buthionine Sulfoximine; Catechols; Cell Line; Cysteine; Cysteinyldopa; Glutathione; Humans; Melanoma; Microscopy, Electron; Monophenol Monooxygenase; Tumor Cells, Cultured | 1996 |
Human (THP-1) macrophages oxidize LDL by a thiol-dependent mechanism.
Topics: Buthionine Sulfoximine; Copper; Cysteine; Cystine; Glutathione; Humans; Kinetics; Lipoproteins, LDL; Macrophages; Oxidation-Reduction; Tumor Cells, Cultured | 1996 |
Cysteine-dependent 5-S-cysteinyldopa formation and its regulation by glutathione in normal epidermal melanocytes.
Topics: Buthionine Sulfoximine; Cell Line; Cells, Cultured; Cysteine; Cysteinyldopa; Enzyme Inhibitors; Epidermal Cells; Epidermis; Glutamate-Cysteine Ligase; Glutathione; Humans; Melanins; Melanocytes; Microscopy, Electron; Oxidative Stress; Skin Pigmentation; Sulfhydryl Compounds | 1996 |
Stimulation of glutathione synthesis of in vitro matured bovine oocytes and its effect on embryo development and freezability.
Topics: Animals; Antimetabolites; Buthionine Sulfoximine; Cattle; Cryopreservation; Cysteamine; Cysteine; Embryonic and Fetal Development; Female; Glutathione; Male; Mercaptoethanol; Oocytes | 1996 |
Loss of GSH, oxidative stress, and decrease of intracellular pH as sequential steps in viral infection.
Topics: Adsorption; Animals; Buthionine Sulfoximine; Cell Line; Cysteine; Disulfides; Dithionitrobenzoic Acid; Dithiothreitol; Dogs; Glutathione; Glutathione Disulfide; Hydrogen-Ion Concentration; Kidney; L-Lactate Dehydrogenase; Methionine; Oxidative Stress; Respirovirus; Sodium-Hydrogen Exchangers; Ultraviolet Rays; Virus Replication | 1997 |
Effect of enterotoxin on glutathione status in the intestinal mucosa.
Topics: Animals; Buthionine Sulfoximine; Cholera Toxin; Cysteine; Endotoxins; Glutathione; Glutathione Disulfide; Intestinal Mucosa; Maleates; Rats; Sulfhydryl Compounds | 1996 |
Pharmacologic modulation of reduced glutathione circadian rhythms with buthionine sulfoximine: relationship with cisplatin toxicity in mice.
Topics: Animals; Buthionine Sulfoximine; Circadian Rhythm; Cisplatin; Cysteine; Digestive System; Enzyme Inhibitors; Glutathione; Kidney; Leukopenia; Liver; Male; Mice; Survival Rate | 1997 |
Biochemical studies on the toxicity of 1, 1'-dimethyl-4, 4'-bipyridylium dichloride in the rat.
Topics: Alanine; Analysis of Variance; Animals; Buthionine Sulfoximine; Cysteine; Herbicides; Lung; Male; Maleates; Microsomes; Microsomes, Liver; Paraquat; Rats; Rats, Wistar | 1997 |
Opposite regulation of tyrosinase and glutathione peroxidase by intracellular thiols in human melanoma cells.
Topics: Buthionine Sulfoximine; Carmustine; Cysteine; Cystine; Glutathione; Glutathione Peroxidase; Humans; Melanins; Melanoma; Monophenol Monooxygenase; Oxidative Stress; Sodium Selenite; Sulfhydryl Compounds; Tumor Cells, Cultured | 1997 |
Use of dipeptides for the synthesis of glutathione by astroglia-rich primary cultures.
Topics: Animals; Astrocytes; Buthionine Sulfoximine; Cells, Cultured; Culture Media; Cysteine; Dipeptides; Enzyme Inhibitors; Glucose; Glutamate-Cysteine Ligase; Glutamic Acid; Glutathione; Glycine; Rats; Rats, Wistar | 1997 |
Effects on interstitial glutathione, cysteine and 5-S-cysteinyldopa of buthionine sulphoximine in human melanoma transplants.
Topics: Acetylcysteine; Animals; Antimetabolites, Antineoplastic; Buthionine Sulfoximine; Cysteine; Cysteinyldopa; Drug Interactions; Enzyme Inhibitors; Glutathione; Humans; Melanoma; Mice; Mice, Inbred BALB C; Mice, Nude; Microdialysis; Neoplasm Transplantation; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1997 |
Oxidation of neutrophil glutathione and protein thiols by myeloperoxidase-derived hypochlorous acid.
Topics: Alkynes; Antioxidants; Buthionine Sulfoximine; Chromatography, High Pressure Liquid; Cysteine; Enzyme Inhibitors; Free Radical Scavengers; Glutathione; Glycine; Humans; Hydrogen Peroxide; Hypochlorous Acid; Neutrophils; Nitric Oxide Synthase; Oxidation-Reduction; Peroxidase; Proteins; Sulfhydryl Compounds; Sulfonamides; Sulfur Radioisotopes; Tetradecanoylphorbol Acetate | 1997 |
Cysteine derivatives protect against UV-induced reactive intermediates in human keratinocytes: the role of glutathione synthesis.
Topics: Buthionine Sulfoximine; Cells, Cultured; Cysteine; Free Radical Scavengers; Glutathione; Humans; Keratinocytes; Photobiology; Ultraviolet Rays | 1997 |
Role of glutathione in protection against noise-induced hearing loss.
Topics: Animals; Antioxidants; Auditory Threshold; Buthionine Sulfoximine; Chromatography, High Pressure Liquid; Cochlea; Cysteine; Evoked Potentials, Auditory, Brain Stem; Female; Glutathione; Guinea Pigs; Hearing Loss, Noise-Induced; Prodrugs; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1998 |
The glutathione dependence of inorganic sulfate formation from L- or D-cysteine in isolated rat hepatocytes.
Topics: Alkynes; Animals; Benzoates; Benzoic Acid; Buthionine Sulfoximine; Cells, Cultured; Cyanides; Cycloserine; Cysteine; Glutathione; Glycine; Kinetics; Liver; Male; Neurotransmitter Agents; Rats; Rats, Sprague-Dawley; Stereoisomerism; Sulfates; Thiosulfates | 1998 |
Modulation of intracellular glutathione and cysteine metabolism in bovine oviduct epithelial cells cultured In vitro.
Topics: Animals; Buthionine Sulfoximine; Cattle; Cells, Cultured; Cysteine; Epithelial Cells; Fallopian Tubes; Female; Glutathione; Ovary | 1998 |
Radiation-sensitive tyrosine phosphorylation of cellular proteins: sensitive to changes in GSH content induced by pretreatment with N-acetyl-L-cysteine or L-buthionine-S,R-sulfoximine.
Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; CHO Cells; Cricetinae; Cysteine; Free Radical Scavengers; Glutathione; Hydrogen Peroxide; Phosphorylation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Radiation Tolerance; Radiation-Protective Agents; Radiation-Sensitizing Agents; Reactive Oxygen Species; Signal Transduction | 1998 |
Oxidative stress as a mechanism of chronic cadmium-induced hepatotoxicity and renal toxicity and protection by antioxidants.
Topics: Acetylcysteine; Alanine Transaminase; Amitrole; Animals; Anti-Inflammatory Agents; Antioxidants; Buthionine Sulfoximine; Cadmium; Cysteine; Drug Combinations; Enzyme Inhibitors; Female; Glutathione; Glycine; Glycyrrhetinic Acid; Kidney; L-Lactate Dehydrogenase; Lipid Peroxidation; Liver; Malondialdehyde; Oxidative Stress; Proteinuria; Rats; Rats, Sprague-Dawley; Steroids; Time Factors; Vitamin E | 1999 |
Molecular basis for hepatic detoxifying enzyme induction by 2-(allylthio)pyrazine in rats in comparison with oltipraz: effects on prooxidant production and DNA degradation.
Topics: Animals; Antioxidants; Blotting, Northern; Buthionine Sulfoximine; Cysteine; Cytochrome P-450 CYP2E1 Inhibitors; DNA Damage; Enzyme Induction; Enzyme Inhibitors; Epoxide Hydrolases; Glutathione; Glutathione Transferase; Immunoblotting; Inactivation, Metabolic; Liver; Male; Microsomes, Liver; NF-kappa B; Oxidants; Pyrazines; Rats; Rats, Sprague-Dawley; Subcellular Fractions; Thiones; Thiophenes | 1999 |
Co-regulation of melanin precursors and tyrosinase in human pigment cells: roles of cysteine and glutathione.
Topics: Buthionine Sulfoximine; Cells, Cultured; Cysteine; Cysteinyldopa; Dihydroxyphenylalanine; Glutathione; Humans; Infant, Newborn; Male; Melanins; Melanocytes; Melanoma; Melanosomes; Monophenol Monooxygenase; Neoplasm Proteins; Skin Neoplasms; Tumor Cells, Cultured; Tyrosine | 1999 |
Comparison of N-acetylcysteine and l-2-oxothiazolidine-4-carboxylate as cysteine deliverers and glutathione precursors in human malignant melanoma transplants in mice.
Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; Cysteine; Cysteinyldopa; Enzyme Inhibitors; Glutathione; Humans; Melanoma; Melanoma, Experimental; Mice; Mice, Nude; Microdialysis; Neoplasm Transplantation; Protein Precursors; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Transplantation, Heterologous; Tumor Cells, Cultured | 2000 |
The role of reduced glutathione and glutathione reductase in the cytotoxicity of chromium (VI) in osteoblasts.
Topics: Alkaline Phosphatase; Animals; Buthionine Sulfoximine; Carcinogens, Environmental; Carmustine; Cell Line, Transformed; Chromium; Cysteine; Drug Interactions; Enzyme Inhibitors; Glutathione; Glutathione Reductase; Osteoblasts; Rats | 2000 |
Glutathione monoethyl ester protects against glutathione deficiencies due to aging and acetaminophen in mice.
Topics: Acetaminophen; Aging; Animals; Buthionine Sulfoximine; Cysteine; Glutathione; Kidney Cortex; Liver; Male; Mice; Mice, Inbred C57BL | 2000 |
Autocrine signals promote osteoblast survival in culture.
Topics: Animals; Animals, Newborn; Antibodies; Antioxidants; Apoptosis; Autocrine Communication; Buthionine Sulfoximine; Catalase; Cell Count; Cell Division; Cell Separation; Cell Survival; Cells, Cultured; Culture Media, Serum-Free; Cysteine; Glutathione; In Situ Nick-End Labeling; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Mice; Osteoblasts; Skull; Statistics, Nonparametric; Superoxide Dismutase; Thymidine | 2000 |
p-Aminophenol-induced liver toxicity: tentative evidence of a role for acetaminophen.
Topics: Acetaminophen; Acetylation; Alanine Transaminase; Aminophenols; Animals; Ascorbic Acid; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Cysteine; Cystine; Dose-Response Relationship, Drug; Drug Synergism; Glutathione; Glutathione Disulfide; L-Iditol 2-Dehydrogenase; Liver; Male; Mice; Mice, Inbred C57BL | 2001 |
Cysteine regulates expression of cysteine dioxygenase and gamma-glutamylcysteine synthetase in cultured rat hepatocytes.
Topics: Alkynes; Animals; Antimetabolites; Buthionine Sulfoximine; Cells, Cultured; Cysteine; Cysteine Dioxygenase; Dioxygenases; Enzyme Inhibitors; Glutamate-Cysteine Ligase; Glycine; Hepatocytes; Isoenzymes; Male; Methionine; Oxygenases; Rats; Rats, Sprague-Dawley | 2001 |
Restoration of glutathione levels in vascular smooth muscle cells exposed to high glucose conditions.
Topics: Aorta; Buthionine Sulfoximine; Cells, Cultured; Cysteine; DNA Damage; Glucose; Glutamate-Cysteine Ligase; Glutathione; Humans; Muscle, Smooth, Vascular; RNA, Messenger; Thioctic Acid | 2001 |
Increasing the glutathione content in a chilling-sensitive maize genotype using safeners increased protection against chilling-induced injury.
Topics: Adaptation, Physiological; Buthionine Sulfoximine; Cold Temperature; Cysteine; Dipeptides; Glutathione; Glutathione Reductase; Herbicides; Oxazines; Plant Roots; Plant Shoots; Zea mays | 2001 |
Altered differentiation in rat and rabbit limb bud micromass cultures by glutathione modulating agents.
Topics: Acetylcysteine; Animals; Antimetabolites; Buthionine Sulfoximine; Cell Differentiation; Cell Survival; Cells, Cultured; Chondrogenesis; Cysteine; Glutathione; Limb Buds; Malates; Oxidation-Reduction; Rabbits; Rats; Rats, Sprague-Dawley; Species Specificity; Staining and Labeling | 2001 |
Hematotoxicity and blood glutathione levels after cisplatin treatment of tumor-bearing mice.
Topics: Animals; Antimetabolites; Antineoplastic Agents; Buthionine Sulfoximine; Cisplatin; Cysteine; Drug Therapy, Combination; Erythrocyte Count; Erythrocytes; Glutathione; Hematocrit; Hemoglobins; Leukocyte Count; Leukocytes; Lymphoma; Mice; Mice, Inbred Strains | 2001 |
Exogenous cysteine and cystine promote cell proliferation in CaCo-2 cells.
Topics: Antimetabolites; Blotting, Western; Buthionine Sulfoximine; Caco-2 Cells; Chromatography, High Pressure Liquid; Cyclin D1; Cysteine; Cystine; Flow Cytometry; G1 Phase; Glutathione; Glutathione Disulfide; Humans; Phosphorylation; Retinoblastoma Protein; S Phase | 2002 |
Recognition of a cysteine substrate by E. coli gamma-glutamylcysteine synthetase probed by sulfoximine-based transition-state analogue inhibitors.
Topics: Buthionine Sulfoximine; Chemical Phenomena; Chemistry, Physical; Crystallography, X-Ray; Cysteine; Enzyme Inhibitors; Escherichia coli; Glutamate-Cysteine Ligase; Indicators and Reagents; Kinetics; Magnetic Resonance Spectroscopy; Mass Spectrometry; Spectrophotometry, Ultraviolet; Substrate Specificity | 2002 |
Electrophile response element-mediated induction of the cystine/glutamate exchange transporter gene expression.
Topics: 5' Flanking Region; Amino Acid Transport System y+; Animals; Base Sequence; Buthionine Sulfoximine; Carrier Proteins; Cell Line; Cricetinae; Cysteine; Cystine; DNA-Binding Proteins; Enzyme Inhibitors; Fibroblasts; Fusion Regulatory Protein 1, Heavy Chain; Gene Expression Regulation; Genes, Reporter; Glutathione; Humans; Maleates; Mice; Mutation; NF-E2-Related Factor 2; Recombinant Fusion Proteins; Response Elements; Sequence Analysis, DNA; Trans-Activators | 2002 |
Composition of seed storage proteins changed by glutathione treatment of soybeans.
Topics: Antigens, Plant; Buthionine Sulfoximine; Cotyledon; Cysteine; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Globulins; Glutathione; Glutathione Disulfide; Glycine max; Seed Storage Proteins; Soybean Proteins | 2002 |
Neuroprotective effects of alpha-tocopherol on oxidative stress in rat striatal cultures.
Topics: alpha-Tocopherol; Animals; Apoptosis; Buthionine Sulfoximine; Cell Survival; Cells, Cultured; Corpus Striatum; Cysteine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fetus; Glutamate-Cysteine Ligase; Hydrogen Peroxide; Molsidomine; Neuroprotective Agents; Nitric Oxide Donors; Oxidative Stress; Paraquat; Protein Kinase C; Rats; S-Nitrosothiols; Staurosporine | 2003 |
Maturation-dependent thiol loss increases chondrocyte susceptibility to apoptosis.
Topics: Acetylcysteine; Alkaline Phosphatase; Animals; Apoptosis; Buthionine Sulfoximine; Cell Differentiation; Cell Survival; Cells, Cultured; Chick Embryo; Chondrocytes; Collagen Type II; Collagen Type IX; Cysteine; Fluorescent Dyes; Gene Expression; Glutathione; Growth Plate; Nitric Oxide; Osteopontin; Oxidation-Reduction; Oxidative Stress; Sialoglycoproteins; Sulfhydryl Compounds; Tretinoin | 2003 |
The role of a formaldehyde dehydrogenase-glutathione pathway in protein S-nitrosation in mammalian cells.
Topics: Acetylcysteine; Aldehyde Oxidoreductases; Animals; Buthionine Sulfoximine; Cells, Cultured; Cysteine; Dehydroepiandrosterone; Glutathione; Glutathione Reductase; HeLa Cells; Humans; Mice; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Nitrosation; Proteins; RNA, Small Interfering; S-Nitrosoglutathione; S-Nitrosothiols | 2003 |
Reduced glutathione is a novel regulator of vernalization-induced bolting in the rosette plant Eustoma grandiflorum.
Topics: Buthionine Sulfoximine; Cysteine; Enzyme Inhibitors; Gentianaceae; Glutathione; Glutathione Disulfide; Light; Oxidative Stress; Photic Stimulation; Reactive Oxygen Species; Reproduction; Seasons; Sulfhydryl Compounds; Temperature | 2004 |
Cysteine but not glutathione modulates the radiosensitivity of human melanoma cells by affecting both survival and DNA damage.
Topics: Buthionine Sulfoximine; Cell Line, Tumor; Cell Survival; Comet Assay; Cysteine; DNA Damage; Dose-Response Relationship, Radiation; Glutathione; Humans; Melanoma; Pigmentation; Radiation Tolerance; Radiation-Sensitizing Agents | 2004 |
Cysteine/cystine couple is a newly recognized node in the circuitry for biologic redox signaling and control.
Topics: Buthionine Sulfoximine; Chromatography, High Pressure Liquid; Colon; Culture Media; Cysteine; Cystine; Cytosol; Digitonin; Disulfides; Enzyme Inhibitors; Epithelial Cells; Glutamate-Cysteine Ligase; Glutathione; Humans; Isothiocyanates; Models, Biological; Oxidation-Reduction; Sulfhydryl Compounds; Thioredoxins | 2004 |
Arabidopsis thaliana glutamate-cysteine ligase: functional properties, kinetic mechanism, and regulation of activity.
Topics: Adenosine Triphosphate; Arabidopsis; Binding Sites; Buthionine Sulfoximine; Chromatography, Gel; Cystamine; Cysteine; Dipeptides; Enzyme Inhibitors; Escherichia coli; Feedback, Physiological; Gene Expression; Glutamate-Cysteine Ligase; Glutamic Acid; Glutathione; Kinetics; Oxidation-Reduction; Oxidative Stress; Protein Conformation; Recombinant Proteins; Spectrometry, Mass, Electrospray Ionization | 2004 |
Argininosuccinate synthetase is reversibly inactivated by S-nitrosylation in vitro and in vivo.
Topics: Animals; Aorta; Arginine; Argininosuccinate Synthase; Blotting, Western; Buthionine Sulfoximine; Catalysis; Cells, Cultured; Cysteine; Dose-Response Relationship, Drug; Glutathione; Glutathione Transferase; Humans; Hydrogen Peroxide; Kinetics; Lipopolysaccharides; Male; Mass Spectrometry; Mice; Mice, Inbred C57BL; Muscle, Smooth; Mutagenesis, Site-Directed; Myocytes, Smooth Muscle; Myoglobin; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitrogen; Protein Processing, Post-Translational; Rats; Recombinant Proteins; Spectrometry, Mass, Electrospray Ionization; Time Factors | 2004 |
Redox state regulates HIF-1alpha and its DNA binding and phosphorylation in salmonid cells.
Topics: Acetylcysteine; Animals; Antimetabolites; Antioxidants; Buthionine Sulfoximine; Cell Line; Cysteine; Dimerization; DNA; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydroxylation; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Immunoblotting; Immunoprecipitation; Oncorhynchus mykiss; Oxidation-Reduction; Oxidative Stress; Oxygen; Phosphorylation; Proline; Propyl Gallate; Proteasome Endopeptidase Complex; Protein Binding; Protein Structure, Tertiary; RNA; Time Factors; Transcription Factors; Transcriptional Activation | 2004 |
Glutathione depletion modulates methanol, formaldehyde and formate toxicity in cultured rat conceptuses.
Topics: Animals; Buthionine Sulfoximine; Cysteine; Embryo, Mammalian; Female; Formaldehyde; Formates; Glutathione; In Vitro Techniques; Male; Methanol; Pregnancy; Rats; Rats, Sprague-Dawley | 2004 |
Cystamine increases L-cysteine levels in Huntington's disease transgenic mouse brain and in a PC12 model of polyglutamine aggregation.
Topics: Animals; Antioxidants; Brain; Buthionine Sulfoximine; Cystamine; Cysteine; Cytoprotection; Disease Models, Animal; Disease Progression; Enzyme Inhibitors; Female; Gene Expression Regulation; Glutathione; Humans; Huntington Disease; Male; Mice; Mice, Transgenic; Neurons; Neuroprotective Agents; Oxidative Stress; PC12 Cells; Peptides; Rats | 2004 |
Effects of BSO and L-cysteine on drug-induced cytotoxicity in primary cell cultures: drug-, cell type-, and species-specific difference.
Topics: Animals; Antimetabolites; Buthionine Sulfoximine; Cell Survival; Cells, Cultured; Cysteine; Epithelial Cells; Glutathione; Hepatocytes; Macaca fascicularis; Male; Rats; Rats, Sprague-Dawley; Species Specificity | 2004 |
Kinetic characteristics of native gamma-glutamylcysteine ligase in the aging housefly, Musca domestica L.
Topics: Adenosine Triphosphate; Aging; Animals; Buthionine Sulfoximine; Cysteine; Feedback, Physiological; Glutamate-Cysteine Ligase; Glutamic Acid; Glutathione; Houseflies; Kinetics | 2005 |
Effect of ribose cysteine pretreatment on hepatic and renal acetaminophen metabolite formation and glutathione depletion.
Topics: Acetaminophen; Animals; Blood Urea Nitrogen; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Cysteine; Glutathione; In Vitro Techniques; Kidney; Kidney Diseases; L-Iditol 2-Dehydrogenase; Liver; Liver Diseases; Male; Mice; Mice, Inbred Strains; Microsomes, Liver; Prodrugs; Protective Agents; Thiazoles; Thiazolidines | 2005 |
Stimulation of colonic mucosal growth associated with oxidized redox status in rats.
Topics: Animals; Buthionine Sulfoximine; Colon; Cysteine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutathione; Glutathione Disulfide; Intestinal Mucosa; Male; Oxidation-Reduction; Rats; Rats, Sprague-Dawley | 2007 |
Schisandrin B-induced increase in cellular glutathione level and protection against oxidant injury are mediated by the enhancement of glutathione synthesis and regeneration in AML12 and H9c2 cells.
Topics: Animals; Antifibrinolytic Agents; Antineoplastic Agents, Alkylating; Buthionine Sulfoximine; Carmustine; Cyclooctanes; Cysteine; Cytoprotection; Enzyme Inhibitors; Glutamate-Cysteine Ligase; Glutathione; Glutathione Reductase; L-Lactate Dehydrogenase; Lignans; Mice; Oxidants; Oxidation-Reduction; Polycyclic Compounds; Vitamin K 3 | 2006 |
Meal cysteine improves postprandial glucose control in rats fed a high-sucrose meal.
Topics: Animals; Area Under Curve; Blood Glucose; Buthionine Sulfoximine; Cysteine; Dietary Carbohydrates; Insulin; Kinetics; Liver; Male; Postprandial Period; Rats; Rats, Wistar; Sucrose | 2007 |
GSH-dependent regulation of Fas-mediated caspase-8 activation by acrolein.
Topics: Acrolein; Alkylation; B-Lymphocytes; Buthionine Sulfoximine; Caspase 8; Caspase Inhibitors; Cell Line; Cysteine; Enzyme Activation; fas Receptor; Glutathione; Humans; Jurkat Cells; T-Lymphocytes | 2007 |
Metabolism of glutathione in tumour cells as evidenced by 1H MRS.
Topics: Buthionine Sulfoximine; Cell Line, Tumor; Cysteine; Glutamic Acid; Glutathione; Humans; Magnetic Resonance Spectroscopy; Neoplasms; Protons; Time Factors | 2007 |
Human p53 is inhibited by glutathionylation of cysteines present in the proximal DNA-binding domain during oxidative stress.
Topics: Acetylcysteine; Amino Acid Sequence; Binding Sites; Buthionine Sulfoximine; Camptothecin; Cell Line, Tumor; Cross-Linking Reagents; Cysteine; Diamide; DNA Damage; DNA-Binding Proteins; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glutaral; Glutathione; Glutathione Disulfide; Humans; Hydrogen Peroxide; Models, Molecular; Oxidative Stress; Phosphorylation; Recombinant Proteins; Tandem Mass Spectrometry; tert-Butylhydroperoxide; Tumor Suppressor Protein p53 | 2007 |
Control of extracellular cysteine/cystine redox state by HT-29 cells is independent of cellular glutathione.
Topics: Biological Transport, Active; Buthionine Sulfoximine; Culture Media; Cysteine; Cystine; Disulfides; Extracellular Space; Glutathione; HT29 Cells; Humans; Kinetics; Oxidation-Reduction; Oxidative Stress; Sulfhydryl Compounds | 2007 |
The cystine/cysteine cycle: a redox cycle regulating susceptibility versus resistance to cell death.
Topics: Amino Acid Transport System y+; Animals; Antimetabolites, Antineoplastic; Apoptosis; Blotting, Northern; Buthionine Sulfoximine; Caspases; Cell Survival; Cysteine; Cystine; Fluorescent Antibody Technique; Glutamic Acid; Glutathione; Humans; Hydrogen Peroxide; Immunoblotting; Lipid Peroxidation; Membrane Potential, Mitochondrial; Mice; Oxidants; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species | 2008 |
Alkenyl group is responsible for the disruption of microtubule network formation in human colon cancer cell line HT-29 cells.
Topics: Adenocarcinoma; Alkenes; Allyl Compounds; Buthionine Sulfoximine; Cell Division; Colonic Neoplasms; Cysteine; Disulfides; Drug Interactions; G2 Phase; Glutathione; HT29 Cells; Humans; Microtubules; Mitosis; Spindle Apparatus; Sulfides | 2008 |
Regulation of the susceptibility to oxidative stress by cysteine availability in pancreatic beta-cells.
Topics: Acetylcysteine; Aldehydes; Amino Acid Transport System y+; Animals; Animals, Newborn; Biological Transport; Buthionine Sulfoximine; Cell Line; Cell Line, Tumor; Cell Nucleus; Cell Survival; Cells, Cultured; Cysteine; Fibroblasts; Gene Expression; Glutathione; Homeodomain Proteins; Humans; Hydrogen Peroxide; Insulin-Secreting Cells; Kinetics; Oxidative Stress; Protein Transport; Rats; Rats, Wistar; Trans-Activators | 2008 |
Darinaparsin induces a unique cellular response and is active in an arsenic trioxide-resistant myeloma cell line.
Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Buthionine Sulfoximine; Cell Line, Tumor; Cell Survival; Cysteine; Drug Resistance, Neoplasm; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glutathione; Humans; Multiple Myeloma; Oxides | 2009 |
Plasmodium falciparum: effect of Solanum nudum steroids on thiol contents and beta-hematin formation in parasitized erythrocytes.
Topics: Animals; Buthionine Sulfoximine; Cysteine; Erythrocytes; Glutathione; Hemeproteins; Linear Models; Malaria, Falciparum; Plant Extracts; Plasmodium falciparum; Solanum; Spiro Compounds; Steroids; Sulfhydryl Compounds; Triterpenes | 2009 |
System x(c)- and thioredoxin reductase 1 cooperatively rescue glutathione deficiency.
Topics: Amino Acid Transport System y+; Animals; Buthionine Sulfoximine; Cell Death; Coculture Techniques; Cysteine; Extracellular Space; Glutamate-Cysteine Ligase; Glutathione; Green Fluorescent Proteins; Intracellular Space; Mice; Thioredoxin Reductase 1; Thioredoxin Reductase 2 | 2010 |
The cystine/cysteine cycle and GSH are independent and crucial antioxidant systems in malignant melanoma cells and represent druggable targets.
Topics: Antioxidants; Arsenic Trioxide; Arsenicals; Blotting, Western; Buthionine Sulfoximine; Cell Survival; Cysteine; Cystine; Glutathione; Glycine; HMGB1 Protein; Humans; Immunohistochemistry; Melanoma; Oxidation-Reduction; Oxides; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Tumor Cells, Cultured | 2011 |
Oxidant-mediated modification of the cellular thiols is sufficient for arginase activation in cultured cells.
Topics: Animals; Arginase; Buthionine Sulfoximine; Cattle; Cell Line, Tumor; Cell Survival; Cysteine; Diamide; Enzyme Activation; Glutathione; Glutathione Synthase; Humans; Kinetics; Ornithine; Oxidants; Oxidation-Reduction; Oxidative Stress | 2012 |
Subcellular distribution of glutathione precursors in Arabidopsis thaliana.
Topics: Arabidopsis; Buthionine Sulfoximine; Cysteine; Dipeptides; Genetic Complementation Test; Glutamic Acid; Glutathione; Glycine; Mesophyll Cells; Mutation; Staining and Labeling; Subcellular Fractions | 2011 |
Repair of oxidative DNA damage is delayed in the Ser326Cys polymorphic variant of the base excision repair protein OGG1.
Topics: Animals; Antimetabolites; Blotting, Western; Buthionine Sulfoximine; Cells, Cultured; Cysteine; Deoxyadenosines; DNA Damage; DNA Glycosylases; DNA Repair; Embryo, Mammalian; Fibroblasts; Flow Cytometry; Gene-Environment Interaction; Glutathione; Humans; Mice; Mice, Knockout; Mutation Rate; Oxidative Stress; Polymorphism, Genetic; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serine; Up-Regulation | 2012 |
miR395 is a general component of the sulfate assimilation regulatory network in Arabidopsis.
Topics: Anion Transport Proteins; Arabidopsis; Arabidopsis Proteins; Buthionine Sulfoximine; Cysteine; DNA-Binding Proteins; Gene Expression Regulation, Plant; Genes, Plant; Metabolic Networks and Pathways; MicroRNAs; Models, Biological; Plants, Genetically Modified; RNA, Plant; Serine; Sulfates; Transcription Factors | 2012 |
Molecular modulated cysteine-selective fluorescent probe.
Topics: Buthionine Sulfoximine; Coumarins; Cysteine; Fluorescence; Glutamate-Cysteine Ligase; Glutathione; Hep G2 Cells; Humans; Microscopy, Confocal; Molecular Probes; Spectrometry, Fluorescence | 2012 |
The effects of thiol modulators on nitrergic nerve- and S-nitrosothiols-induced relaxation in duodenum.
Topics: Analysis of Variance; Animals; Buthionine Sulfoximine; Cysteine; Diuretics; Dose-Response Relationship, Drug; Duodenum; Ethacrynic Acid; Female; Glutamate-Cysteine Ligase; Glutathione Transferase; Male; Mice; Muscle Relaxation; Nitric Oxide; Nitric Oxide Donors; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione; S-Nitrosothiols; Sulfhydryl Reagents; Sulfobromophthalein; Synaptic Transmission; Vasodilator Agents | 2013 |
Metabolic pathways leading to detoxification of triptolide, a major active component of the herbal medicine Tripterygium wilfordii.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Buthionine Sulfoximine; Cysteine; Cytochrome P-450 Enzyme System; Dipeptides; Diterpenes; Enzyme Inhibitors; Epoxy Compounds; Glutathione; Humans; Inactivation, Metabolic; Male; Metabolic Networks and Pathways; Mice; Microsomes, Liver; NADP; Phenanthrenes; Plants, Medicinal; Triazoles; Tripterygium | 2014 |
Selective targeting of the cysteine proteome by thioredoxin and glutathione redox systems.
Topics: Antioxidants; Auranofin; Buthionine Sulfoximine; Cysteine; Enzyme Inhibitors; Glutathione; Glutathione Disulfide; HT29 Cells; Humans; Metabolic Networks and Pathways; Oxidation-Reduction; Proteome; Proteomics; Signal Transduction; Thioredoxin-Disulfide Reductase; Thioredoxins | 2013 |
Mechanism of immunotoxicological effects of tributyltin chloride on murine thymocytes.
Topics: Animals; Apoptosis; Buthionine Sulfoximine; Calcium; Caspase 3; Caspase Inhibitors; Cell Survival; Cells, Cultured; Cysteine; DNA Damage; Male; Membrane Potential, Mitochondrial; Mice; Mice, Inbred BALB C; Mitochondria; Reactive Oxygen Species; Thymocytes; Thymus Gland; Trialkyltin Compounds | 2014 |
L-Cysteine inhibits root elongation through auxin/PLETHORA and SCR/SHR pathway in Arabidopsis thaliana.
Topics: Arabidopsis; Arabidopsis Proteins; Buthionine Sulfoximine; Cysteine; Down-Regulation; Green Fluorescent Proteins; Indoleacetic Acids; Meristem; Oxidation-Reduction; Peroxisomes; Plant Roots; Serine; Signal Transduction; Stem Cell Niche; Transcription Factors | 2015 |
Effects of exogenous glutathione and cysteine on growth, lead accumulation, and tolerance of Iris lactea var. chinensis.
Topics: Analysis of Variance; Biodegradation, Environmental; Buthionine Sulfoximine; Cysteine; Electrophoresis, Polyacrylamide Gel; Fluorescence; Gene Expression Regulation, Plant; Glutathione; Iris Plant; Lead; Phytochelatins; Plant Leaves; Plant Roots; Spectrophotometry, Atomic; Sulfhydryl Compounds | 2015 |
N-acetylcysteine stimulates protein synthesis in enterocytes independently of glutathione synthesis.
Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; Cell Line; Cell Proliferation; Cysteine; Enterocytes; Eukaryotic Initiation Factors; Glutathione; Maleates; Protein Biosynthesis; Real-Time Polymerase Chain Reaction; Sus scrofa; TOR Serine-Threonine Kinases | 2016 |
Lysine- and cysteine-based protein adductions derived from toxic metabolites of 8-epidiosbulbin E acetate.
Topics: Activation, Metabolic; Animals; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Cysteine; Dioscorea; Diterpenes; In Vitro Techniques; Ketoconazole; Lysine; Male; Medicine, East Asian Traditional; Mice; Microsomes, Liver; Oxidation-Reduction; Proteins | 2016 |
Phytochelatins play key roles for the difference in root arsenic accumulation of different Triticum aestivum cultivars in comparison with arsenate uptake kinetics and reduction.
Topics: Arsenates; Arsenic; Buthionine Sulfoximine; Cysteine; Glutathione; Kinetics; Oxidation-Reduction; Phytochelatins; Plant Proteins; Plant Roots; Plant Shoots; Seedlings; Triticum | 2017 |
S-Alk(en)ylmercaptocysteine suppresses LPS-induced pro-inflammatory responses in murine macrophages through inhibition of NF-κB pathway and modulation of thiol redox status.
Topics: Animals; Anti-Inflammatory Agents; Buthionine Sulfoximine; Cysteine; Gene Expression Regulation; Glutamate-Cysteine Ligase; Glutathione; I-kappa B Kinase; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Mice; NF-E2-Related Factor 2; NF-kappa B; Nitric Oxide Synthase Type II; Oxidation-Reduction; Oxidative Stress; RAW 264.7 Cells; Signal Transduction; Tumor Necrosis Factor-alpha | 2018 |
Arabidopsis γ-glutamylcyclotransferase affects glutathione content and root system architecture during sulfur starvation.
Topics: Arabidopsis; Arabidopsis Proteins; Buthionine Sulfoximine; Cysteine; DNA, Bacterial; gamma-Glutamylcyclotransferase; Gene Expression Regulation, Plant; Glutamic Acid; Glutathione; Meristem; Models, Biological; Mutation; Phenotype; Plant Roots; Promoter Regions, Genetic; RNA, Messenger; Sulfur | 2019 |
S-nitrosocysteine and glutathione depletion synergize to induce cell death in human tumor cells: Insights into the redox and cytotoxic mechanisms.
Topics: Buthionine Sulfoximine; Cell Death; Cysteine; Glutathione; Humans; Oxidation-Reduction; S-Nitrosothiols | 2020 |
L-buthionine sulfoximine encapsulated hollow calcium peroxide as a chloroperoxidase nanocarrier for enhanced enzyme dynamic therapy.
Topics: Buthionine Sulfoximine; Calcium; Chloride Peroxidase; Cysteine; Glutathione; Hyaluronic Acid; Hydrogen Peroxide; Ligases; Peroxides | 2022 |
Purpurin ameliorates alcohol-induced hepatotoxicity by reducing ROS generation and promoting Nrf2 expression.
Topics: Alanine Transaminase; Animals; Anthraquinones; Antioxidants; Aspartate Aminotransferases; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Cysteine; Cytochrome P-450 CYP2E1; Ethanol; Glutathione; Ligands; Mice; NF-E2-Related Factor 2; Oxidative Stress; Reactive Oxygen Species | 2022 |