buthionine sulfoximine has been researched along with carmustine in 67 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (14.93) | 18.7374 |
| 1990's | 35 (52.24) | 18.2507 |
| 2000's | 20 (29.85) | 29.6817 |
| 2010's | 2 (2.99) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Guenthner, TM; Jevtović-Todorović, V | 1 |
| Allalunis-Turner, MJ; Barron, GM; Day, RS; Dobler, K; Urtasun, RC | 1 |
| Canada, AT; Romero, MJ | 1 |
| Brunmark, A; Ollinger, K | 1 |
| Allalunis-Turner, MJ; Allen, PB; Aronyk, KE; Day, RS; Fulton, DS; Huyser-Wierenga, D; McKean, JD; Petruk, KC; Urtasun, RC; Weir, BK | 1 |
| Hiraishi, H; Ivey, KJ; Mutoh, H; Ota, S; Razandi, M; Sugimoto, T; Terano, A | 1 |
| Costarides, AP; Green, K; Riley, MV | 2 |
| Mehendale, HM; Utley, WS | 1 |
| Benz, CC; Ford, JM; Hait, WN; Matlin, SA | 1 |
| Brand, S; Forrester, T; Golden, M; Swales, J | 1 |
| Beaujean, F; Goavec, M; Ito, H; Morizet, J; Rousseau, V; Stanislawski, M | 1 |
| Costarides, A; Green, K; Recasens, JF; Riley, MV | 1 |
| DeHart, PD; Nadeau, DM; Simon, RH | 1 |
| Abarzua, M; Davis, JA; Kiani, T; Weinberg, JM | 1 |
| Goavec, M; Ito, H; Rousseau, V; Stanislawski, M | 1 |
| Bodell, WJ; Doane-Setzer, P; Evans, CG; Smith, MT; Tokuda, K | 1 |
| Michiels, C; Remacle, J | 1 |
| Deen, DF; Hunter, KJ; Marton, LJ | 1 |
| Cieslinski, DA; Humes, HD; Messana, JM; O'Connor, RP | 1 |
| Adams, GE | 1 |
| Callahan, KS; Harker, LA; Harlan, JM; Levine, JD; Schwartz, BR | 1 |
| Gardiner, CS; Reed, DJ | 1 |
| Graham, A; Wood, JL | 1 |
| Buttin, G; De Saint Vincent, BR; Lunel-Orsini, C | 1 |
| Awad, JA; Burk, RF; Roberts, LJ | 1 |
| Hempel, SL; Wessels, DA | 1 |
| Chigurupati, R; Frischer, H; Kennedy, EJ; Sivarajan, M | 1 |
| Eisert, DR; Freeman, ML; Meredith, MJ; Sierra-Rivera, E; Voorhees, GJ | 1 |
| Harris, C; Hiranruengchok, R | 1 |
| Elliott, SJ; Henschke, PN | 1 |
| Averill-Bates, DA; Przybytkowski, E | 1 |
| Ali-Osman, F; Antoun, G; Gagucas, E; Rajagopal, S; Wang, H | 1 |
| Domann, FE; Oberley, LW; Oberley, TD; St Clair, DK; Yan, T; Zhong, W | 1 |
| Luperchio, S; Tamir, S; Tannenbaum, SR | 1 |
| Billiar, TR; Chough, V; Di Silvio, M; Harbrecht, BG; Kim, YM; Simmons, RL | 1 |
| Padgett, CM; Whorton, AR | 1 |
| Harstrick, A; Rustum, YM; Seeber, S; Vanhoefer, U; Yin, MB | 1 |
| Benathan, M | 1 |
| al-Bassam, M; Buzaid, AC; Dasgupta, C; Fruehauf, JP; Kyshtoobayeva, A; Milovanovic, T; Parker, RJ; Zonis, S | 2 |
| Dröge, W; El Benna, J; Galter, D; Klein, G; Schmid, E | 1 |
| Hiraishi, H; Ivey, KJ; Shimada, T; Terano, A | 1 |
| Cunha, FQ; Ferreira, SH; Fonseca, SG; Hothersall, JS; Noronha-Dutra, AA; Romão, PR | 1 |
| Lim, R; Oberley, LW; Yan, T; Zhong, W | 1 |
| Grant, MH; Ning, J | 1 |
| Andersen, HU; Darville, MI; Eizirik, DL; Karlsen, AE; Mandrup-Poulsen, T; Nikulina, MA | 1 |
| Bhamre, S; Cohen, HJ; Nuzzo, RL; Olshen, RA; Whitin, JC | 1 |
| Krysan, K; Lou, MF; Raghavachari, N; Xing, K | 1 |
| Aw, TY; Fujimoto, K; Iwakiri, R; Noda, T | 1 |
| Colpaert, EE; Lefebvre, RA; Timmermans, JP | 1 |
| Haddad, JJ; Lauterbach, R; Saadé, NE; Safieh-Garabedian, B | 1 |
| Burger, RA; Fruehauf, JP; Monk, BJ; Parker, R; Radany, EH; Redpath, L | 1 |
| Christen, S; Ferriero, DM; Francisco, C; Gregory, G; Manabat, C; Täuber, M; Vexler, ZS; Wong, A | 1 |
| Ahmad, R; Arora, K; Gupta, S; Katiyar, D; Khan, MA; Murthy, PK; Srivastava, AK; Tewari, N; Tiwari, VK; Tripathi, RP; Walter, RD | 1 |
| Li, S; Li, X; Rozanski, GJ | 1 |
| Berlanda, J; Kiesslich, T; Krammer, B; Oberdanner, CB; Obermair, FJ; Plaetzer, K | 1 |
| Assreuy, J; Freitas, MS; Santos-Silva, MC | 1 |
| Anding, P; Li, S; Li, X; Liu, D; Lou, MF; Roy, SK; Rozanski, GJ; Xu, Z | 1 |
| Chiu, PY; Ko, KM | 1 |
| Grant, MH; Henderson, C; Kupper, C; Lalaouni, A | 1 |
| Boyle, JP; Hettiarachchi, NT; Peers, C; Wilkinson, JA | 1 |
| Castranova, V; Gunther, MR; Kisin, E; Kommineni, C; Murray, AR; Shvedova, AA | 1 |
| Jang, HD; Kim, GN | 1 |
| Gaskins, HR; Henderson, JL; Henry, JJ; Kenis, PJ; Kolossov, VL; Lin, C; Rund, LA; Schook, LB; Timp, G; Trump, L; Tsvid, G | 1 |
| Berg, K; Hothersall, JS; Jonsson, M; Kubin, A; Olsen, CE; Theodossiou, TA | 1 |
67 other study(ies) available for buthionine sulfoximine and carmustine
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Depletion of a discrete nuclear glutathione pool by oxidative stress, but not by buthionine sulfoximine. Correlation with enhanced alkylating agent cytotoxicity to human melanoma cells in vitro.
Topics: Buthionine Sulfoximine; Carmustine; Cell Division; Cell Nucleus; Cytosol; Doxorubicin; Drug Synergism; Glutathione; Glutathione Disulfide; Humans; Melanoma; Melphalan; Methionine Sulfoximine; Oxidation-Reduction; Tumor Cells, Cultured | 1992 |
Heterogeneity in response to treatment with buthionine sulfoximine or interferon in human malignant glioma cells.
Topics: Buthionine Sulfoximine; Carmustine; Humans; In Vitro Techniques; Interferon-alpha; Mechlorethamine; Methionine Sulfoximine; Recombinant Proteins; Tumor Cells, Cultured | 1992 |
The evaluation of Escherichia coli as a model for oxidant stress in mammalian hepatocytes: role of glutathione.
Topics: Animals; Buthionine Sulfoximine; Carmustine; Escherichia coli; Glutathione; Glutathione Reductase; Hydrogen Peroxide; Liver; Methionine Sulfoximine; Models, Biological; Oxidation-Reduction; Paraquat; Peroxides; Superoxides; tert-Butylhydroperoxide | 1991 |
Effect of hydroxy substituent position on 1,4-naphthoquinone toxicity to rat hepatocytes.
Topics: Animals; Buthionine Sulfoximine; Carmustine; Cell Survival; Dicumarol; Glutathione; Liver; Male; Methionine Sulfoximine; Mitochondria, Liver; Molecular Structure; Naphthoquinones; Oxidation-Reduction; Oxygen Consumption; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1991 |
Glutathione levels and chemosensitizing effects of buthionine sulfoximine in human malignant glioma cells.
Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Brain Neoplasms; Buthionine Sulfoximine; Carmustine; Child; Drug Screening Assays, Antitumor; Drug Synergism; Female; Glioma; Glutathione; Humans; Male; Mechlorethamine; Methionine Sulfoximine; Middle Aged; Tumor Cells, Cultured | 1991 |
Antioxidant defenses of cultured gastric cells against oxygen metabolites: role of GSH redox cycle and endogenous catalase.
Topics: Animals; Antimetabolites; Buthionine Sulfoximine; Carmustine; Catalase; Cells, Cultured; Chromium; Female; Gastric Mucosa; Glucose; Glucose Oxidase; Glutathione; Glutathione Reductase; Hydrogen Peroxide; Lipid Peroxidation; Male; Maleates; Methionine Sulfoximine; Oxidation-Reduction; Oxygen; Rats; Rats, Inbred Strains | 1991 |
Roles of catalase and the glutathione redox cycle in the regulation of anterior-chamber hydrogen peroxide.
Topics: Amitrole; Animals; Anterior Chamber; Anterior Eye Segment; Antimetabolites; Aqueous Humor; Ascorbic Acid; Buthionine Sulfoximine; Carmustine; Catalase; Glutathione; Glutathione Reductase; Hydrogen Peroxide; Methionine Sulfoximine; Oxidation-Reduction; Rabbits | 1991 |
Evidence for stimulated glutathione synthesis by phenobarbital pretreatment during an oxidative challenge in isolated hepatocytes.
Topics: Animals; Buthionine Sulfoximine; Carmustine; Glutathione; Glutathione Reductase; Homeostasis; In Vitro Techniques; L-Lactate Dehydrogenase; Liver; Male; Methionine Sulfoximine; Oxidation-Reduction; Phenobarbital; Rats; Rats, Inbred Strains; Trypan Blue; Vitamin K | 1991 |
Modulation of resistance to alkylating agents in cancer cell by gossypol enantiomers.
Topics: Alkylating Agents; Animals; Breast Neoplasms; Buthionine Sulfoximine; Carcinoma 256, Walker; Carmustine; Cell Division; Cell Line; Chlorambucil; Cisplatin; Drug Antagonism; Drug Resistance; Glutathione Transferase; Gossypol; Humans; In Vitro Techniques; Isomerism; Melphalan; Methionine Sulfoximine; Rats | 1991 |
Role of glutathione in the regulation of anterior chamber hydrogen peroxide.
Topics: Amitrole; Animals; Anterior Chamber; Antimetabolites; Buthionine Sulfoximine; Carmustine; Catalase; Ciliary Body; Glutathione; Glutathione Reductase; Hydrogen Peroxide; Iris; Methionine Sulfoximine; Oxidation-Reduction; Rabbits | 1990 |
Reduction in vitro of red cell glutathione reproduces defects of cellular sodium transport seen in oedematous malnutrition.
Topics: Adult; Antimetabolites; Buthionine Sulfoximine; Carmustine; Erythrocyte Membrane; Erythrocytes; Glutathione; Humans; In Vitro Techniques; Kwashiorkor; Male; Methionine Sulfoximine; Protein-Energy Malnutrition; Sodium; Sodium Channels | 1990 |
Enhanced in vitro cytotoxicity of 1,3-bis-(2-chloroethyl)-1-nitrosourea or buthionine sulfoximine combined with a reactive oxygen-generating enzyme immunotoxin.
Topics: Antineoplastic Combined Chemotherapy Protocols; Buthionine Sulfoximine; Carmustine; Cell Survival; Cells, Cultured; Drug Synergism; Glucose Oxidase; Glutathione; Humans; Immunotoxins; Lactoperoxidase; Lymphoma; Methionine Sulfoximine; T-Lymphocytes | 1990 |
The effects of ascorbate, 3-aminotriazole, and 1,3-bis-(2-chloroethyl)-1-nitrosourea on hydrogen peroxide levels in the rabbit aqueous humor.
Topics: Amitrole; Animals; Aqueous Humor; Ascorbic Acid; Buthionine Sulfoximine; Carmustine; Catalase; Ciliary Body; Glutathione; Glutathione Reductase; Hydrogen Peroxide; Iris; Methionine Sulfoximine; Rabbits | 1989 |
Resistance of rat pulmonary alveolar epithelial cells to neutrophil- and oxidant-induced injury.
Topics: Amitrole; Animals; Azides; Buthionine Sulfoximine; Carmustine; Catalase; Cells, Cultured; Epithelium; Glutathione; Glyceraldehyde-3-Phosphate Dehydrogenases; Hydrogen Peroxide; Methionine Sulfoximine; Neutrophils; Oxidation-Reduction; Pulmonary Alveoli; Rats; Rats, Inbred F344 | 1989 |
Relationship between cell adenosine triphosphate and glutathione content and protection by glycine against hypoxic proximal tubule cell injury.
Topics: Adenosine Triphosphate; Animals; Buthionine Sulfoximine; Carmustine; Glutathione; Glycine; Kidney Tubules, Proximal; L-Lactate Dehydrogenase; Methionine Sulfoximine; Oxygen; Potassium; Rabbits | 1989 |
Immunotoxins containing glucose oxidase and lactoperoxidase with tumoricidal properties: in vitro killing effectiveness in a mouse plasmacytoma cell model.
Topics: Animals; Bone Marrow; Buthionine Sulfoximine; Carmustine; Dose-Response Relationship, Immunologic; Drug Synergism; Glucose Oxidase; Glutathione; Immunization, Passive; Immunotherapy; Immunotoxins; Lactoperoxidase; Methionine Sulfoximine; Mice; Mice, Inbred BALB C; Peroxidases; Plasmacytoma | 1989 |
Glutathione and related enzymes in rat brain tumor cell resistance to 1,3-bis(2-chloroethyl)-1-nitrosourea and nitrogen mustard.
Topics: Animals; Brain Neoplasms; Buthionine Sulfoximine; Carmustine; Cell Line; Cell Survival; Chromatography, High Pressure Liquid; Clone Cells; Dinitrochlorobenzene; Drug Resistance; gamma-Glutamyltransferase; Glioma; Glutathione; Glutathione Transferase; Lomustine; Mechlorethamine; Methionine Sulfoximine; Rats; Semustine | 1987 |
Use of the inhibition of enzymatic antioxidant systems in order to evaluate their physiological importance.
Topics: Amitrole; Buthionine Sulfoximine; Carmustine; Catalase; Cell Survival; Ditiocarb; Fibroblasts; Glutamate-Cysteine Ligase; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Humans; Methionine Sulfoximine; Superoxide Dismutase; Thiomalates | 1988 |
Changes in the glutathione content of rat 9L cells induced by treatment with the ornithine decarboxylase inhibitor alpha-difluoromethylornithine.
Topics: Alkylating Agents; Animals; Buthionine Sulfoximine; Carmustine; Eflornithine; Glutathione; Methionine Sulfoximine; Ornithine Decarboxylase Inhibitors; Putrescine; Rats; Spermidine | 1987 |
Glutathione protects against exogenous oxidant injury to rabbit renal proximal tubules.
Topics: Adenosine Triphosphate; Animals; Buthionine Sulfoximine; Carmustine; Cell Membrane Permeability; Cell Survival; Glutathione; Kidney Tubules, Proximal; Kinetics; Lipid Peroxides; Malates; Malondialdehyde; Methionine Sulfoximine; Oxidation-Reduction; Oxygen Consumption; Peroxides; Potassium; Rabbits; tert-Butylhydroperoxide | 1988 |
Radiosensitizers: a conference preview.
Topics: Animals; Aziridines; Buthionine Sulfoximine; Carmustine; Combined Modality Therapy; Drug Synergism; Etanidazole; Humans; Ketones; Lomustine; Maleates; Methionine Sulfoximine; Mice; Misonidazole; Neoplasms; Nitroimidazoles; Radiation-Sensitizing Agents | 1984 |
Glutathione redox cycle protects cultured endothelial cells against lysis by extracellularly generated hydrogen peroxide.
Topics: Animals; Blood Vessels; Buthionine Sulfoximine; Carmustine; Cattle; Cells, Cultured; Dinitrochlorobenzene; Endothelium; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Humans; Hydrogen Peroxide; Maleates; Methionine Sulfoximine; Oxidation-Reduction | 1984 |
Glutathione redox cycle-driven recovery of reduced glutathione after oxidation by tertiary-butyl hydroperoxide in preimplantation mouse embryos.
Topics: Animals; Antimetabolites; Blastocyst; Buthionine Sulfoximine; Carmustine; Dose-Response Relationship, Drug; Female; Glutathione; Glutathione Disulfide; In Vitro Techniques; Kinetics; Methionine Sulfoximine; Mice; Mice, Inbred Strains; Oxidation-Reduction; Peroxides; Reactive Oxygen Species; Superovulation; tert-Butylhydroperoxide | 1995 |
The role of thiols in oxidation of low-density lipoprotein by macrophages.
Topics: Antimetabolites; Buthionine Sulfoximine; Carmustine; Cell Line; Cell-Free System; Cystine; Humans; Kinetics; Lipoproteins, LDL; Macrophages; Methionine Sulfoximine; Oxidation-Reduction; S-Adenosylmethionine; Sulfhydryl Compounds; Thiobarbituric Acid Reactive Substances; Tubercidin | 1995 |
A glutathione depletion selectively imposed on mu glutathione S-transferase overproducing cells increases nitrogen mustard toxicity.
Topics: Animals; Buthionine Sulfoximine; Carmustine; Cell Line; Cell Survival; Cisplatin; Cricetinae; Cricetulus; Doxorubicin; Glutathione; Glutathione Transferase; Inactivation, Metabolic; Mechlorethamine; Methionine Sulfoximine | 1995 |
Effect of selenium deficiency and glutathione-modulating agents on diquat toxicity and lipid peroxidation in rats.
Topics: Animals; Antimetabolites; Arachidonic Acids; Buthionine Sulfoximine; Carmustine; Diquat; Glutathione; Ketones; Kidney; Lipid Peroxidation; Liver; Lung; Male; Methionine Sulfoximine; Rats; Rats, Inbred F344; Selenium | 1994 |
Prostaglandin E2 synthesis after oxidant stress is dependent on cell glutathione content.
Topics: 3T3 Cells; Animals; Antimetabolites; Arachidonic Acid; Buthionine Sulfoximine; Carmustine; Chromatography, High Pressure Liquid; Dinitrochlorobenzene; Dinoprostone; Glutathione; Hydrogen Peroxide; Kinetics; Methionine Sulfoximine; Mice; Proteins | 1994 |
Glutathione, cell proliferation, and 1,3-bis-(2-chloroethyl)-1-nitrosourea in K562 leukemia.
Topics: Buthionine Sulfoximine; Carmustine; Cell Cycle; Cell Division; Cell Line; DNA Repair; DNA, Neoplasm; Dose-Response Relationship, Drug; Glutathione; Glutathione Reductase; Humans; Kinetics; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Methionine Sulfoximine; Tumor Cells, Cultured | 1993 |
Synthesis of hsp-70 is enhanced in glutathione-depleted Hep G2 cells.
Topics: Buthionine Sulfoximine; Carmustine; Cells, Cultured; Dimethyl Sulfoxide; Glutathione; Heat-Shock Proteins; Hot Temperature; Humans; Methionine Sulfoximine; Oxidation-Reduction; RNA, Messenger | 1993 |
Glutathione oxidation and embryotoxicity elicited by diamide in the developing rat conceptus in vitro.
Topics: Animals; Antimetabolites; Buthionine Sulfoximine; Carmustine; Chromatography, High Pressure Liquid; Diamide; Embryo, Mammalian; Female; Glutaredoxins; Glutathione; Glutathione Disulfide; In Vitro Techniques; Methionine Sulfoximine; Oxidation-Reduction; Oxidoreductases; Protein Disulfide Reductase (Glutathione); Rats; Rats, Sprague-Dawley | 1993 |
Oxidized glutathione decreases luminal Ca2+ content of the endothelial cell ins(1,4,5)P3-sensitive Ca2+ store.
Topics: Animals; Antimetabolites; Antioxidants; Buthionine Sulfoximine; Calcium; Carmustine; Cattle; Cells, Cultured; Cytosol; Endothelium, Vascular; Glutathione; Glutathione Disulfide; Hydroquinones; Inositol 1,4,5-Trisphosphate; Methionine Sulfoximine; Oxidants; Peroxides; Pulmonary Artery; Signal Transduction; tert-Butylhydroperoxide | 1995 |
Correlation between glutathione and stimulation of the pentose phosphate cycle in situ in Chinese hamster ovary cells exposed to hydrogen peroxide.
Topics: Amitrole; Animals; Buthionine Sulfoximine; Carmustine; CHO Cells; Cricetinae; Enzyme Inhibitors; Glucosephosphate Dehydrogenase; Glutamate-Cysteine Ligase; Glutathione; Hydrogen Peroxide; Kinetics; Methionine Sulfoximine; Oxidation-Reduction; Paraquat; Pentose Phosphate Pathway | 1996 |
Buthionine sulfoximine induction of gamma-L-glutamyl-L-cysteine synthetase gene expression, kinetics of glutathione depletion and resynthesis, and modulation of carmustine-induced DNA-DNA cross-linking and cytotoxicity in human glioma cells.
Topics: Antineoplastic Agents, Alkylating; Base Sequence; Buthionine Sulfoximine; Carmustine; Cell Survival; DNA; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Glioma; Glutamate-Cysteine Ligase; Glutathione; Humans; Kinetics; Methionine Sulfoximine; Molecular Sequence Data | 1996 |
Inhibition of cell growth and sensitization to oxidative damage by overexpression of manganese superoxide dismutase in rat glioma cells.
Topics: Animals; Antineoplastic Agents, Alkylating; Buthionine Sulfoximine; Carmustine; Catalase; Cell Division; Enzyme Inhibitors; Female; Gamma Rays; Gene Expression; Glioma; Glutamate-Cysteine Ligase; Glutathione Peroxidase; Humans; Mice; Mice, Nude; Oxidative Stress; Pyruvic Acid; Radiation Tolerance; Rats; RNA, Messenger; RNA, Neoplasm; Superoxide Dismutase; Transfection; Tumor Cells, Cultured | 1996 |
NO-induced oxidative stress and glutathione metabolism in rodent and human cells.
Topics: Animals; Buthionine Sulfoximine; Carmustine; Cell Line; Cell Survival; CHO Cells; Cricetinae; Enzyme Inhibitors; Glutamate-Cysteine Ligase; Glutathione; Glutathione Disulfide; Glutathione Reductase; Humans; Nitric Oxide; Oxidative Stress; Reactive Oxygen Species | 1996 |
Glutathione regulates nitric oxide synthase in cultured hepatocytes.
Topics: Animals; Buthionine Sulfoximine; Carmustine; Cells, Cultured; Enzyme Inhibitors; Glutathione; Liver; Male; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley | 1997 |
Glutathione redox cycle regulates nitric oxide-mediated glyceraldehyde-3-phosphate dehydrogenase inhibition.
Topics: Animals; Buthionine Sulfoximine; Carmustine; Cattle; Cells, Cultured; Dithiothreitol; Endothelium, Vascular; Enzyme Inhibitors; Glutathione; Glutathione Reductase; Glyceraldehyde-3-Phosphate Dehydrogenases; Nitric Oxide; Oxidation-Reduction | 1997 |
Carbamoylation of glutathione reductase by N,N-bis(2-chloroethyl)-N- nitrosourea associated with inhibition of multidrug resistance protein (MRP) function.
Topics: Antineoplastic Agents, Alkylating; ATP-Binding Cassette Transporters; Buthionine Sulfoximine; Carmustine; Drug Resistance, Multiple; Glutathione; Glutathione Reductase; Humans; Multidrug Resistance-Associated Proteins; RNA, Messenger; Tumor Cells, Cultured | 1997 |
Opposite regulation of tyrosinase and glutathione peroxidase by intracellular thiols in human melanoma cells.
Topics: Buthionine Sulfoximine; Carmustine; Cysteine; Cystine; Glutathione; Glutathione Peroxidase; Humans; Melanins; Melanoma; Monophenol Monooxygenase; Oxidative Stress; Sodium Selenite; Sulfhydryl Compounds; Tumor Cells, Cultured | 1997 |
Selective and synergistic activity of L-S,R-buthionine sulfoximine on malignant melanoma is accompanied by decreased expression of glutathione-S-transferase.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Breast Neoplasms; Buthionine Sulfoximine; Carmustine; Drug Synergism; Female; Glutathione; Glutathione Transferase; Humans; Melanins; Melanoma; Ovarian Neoplasms; Tumor Cells, Cultured | 1997 |
Redox priming of the insulin receptor beta-chain associated with altered tyrosine kinase activity and insulin responsiveness in the absence of tyrosine autophosphorylation.
Topics: Animals; Antimetabolites; Antineoplastic Agents, Alkylating; Antioxidants; Buthionine Sulfoximine; Carmustine; CHO Cells; Cricetinae; Enzyme Induction; Insulin; Oxidation-Reduction; Phosphoric Monoester Hydrolases; Phosphorylation; Protein-Tyrosine Kinases; Receptor, Insulin; Transfection; Tyrosine | 1998 |
Melanin content and downregulation of glutathione S-transferase contribute to the action of L-buthionine-S-sulfoximine on human melanoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Buthionine Sulfoximine; Carmustine; Down-Regulation; Drug Resistance; Enzyme Inhibitors; Female; Glutamate-Cysteine Ligase; Glutathione Transferase; Humans; Melanins; Melanoma; Melphalan; Ovarian Neoplasms; Tumor Cells, Cultured | 1998 |
Role of antioxidant defenses against ethanol-induced damage in cultured rat gastric epithelial cells.
Topics: Amitrole; Animals; Antioxidants; Buthionine Sulfoximine; Carmustine; Catalase; Cells, Cultured; Chromium Radioisotopes; Endothelium; Enzyme Inhibitors; Epithelial Cells; Ethanol; Female; Gastric Mucosa; Glutathione; Male; NADH Dehydrogenase; Oxidation-Reduction; Rats; Superoxides | 1999 |
Glutathione protects macrophages and Leishmania major against nitric oxide-mediated cytotoxicity.
Topics: Animals; Buthionine Sulfoximine; Carmustine; Cell Survival; Enzyme Inhibitors; Glutathione; Leishmania major; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Nitric Oxide; Penicillamine | 1999 |
Expression of superoxide dismutases, catalase, and glutathione peroxidase in glioma cells.
Topics: Animals; Blotting, Western; Buthionine Sulfoximine; Carmustine; Catalase; Fluorescent Antibody Technique; Gene Expression; Glioma; Glutathione Peroxidase; Humans; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Superoxide Dismutase; Tumor Cells, Cultured | 1999 |
The role of reduced glutathione and glutathione reductase in the cytotoxicity of chromium (VI) in osteoblasts.
Topics: Alkaline Phosphatase; Animals; Buthionine Sulfoximine; Carcinogens, Environmental; Carmustine; Cell Line, Transformed; Chromium; Cysteine; Drug Interactions; Enzyme Inhibitors; Glutathione; Glutathione Reductase; Osteoblasts; Rats | 2000 |
Glutathione depletion inhibits IL-1 beta-stimulated nitric oxide production by reducing inducible nitric oxide synthase gene expression.
Topics: Animals; Antineoplastic Agents, Alkylating; Buthionine Sulfoximine; Carmustine; Cell Separation; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flow Cytometry; Gene Expression; Glutathione; Insulin; Insulinoma; Interleukin-1; Islets of Langerhans; Maleates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Oxidation-Reduction; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors | 2000 |
Intracellular reduction of selenite into glutathione peroxidase. Evidence for involvement of NADPH and not glutathione as the reductant.
Topics: Animals; Buthionine Sulfoximine; Carmustine; Cell Line; Cricetinae; Enzyme Inhibitors; Glucosephosphate Dehydrogenase; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Humans; Male; Methylene Blue; NADP; Oxidation-Reduction; Sodium Selenite; Tumor Cells, Cultured | 2000 |
Regulation of thioltransferase expression in human lens epithelial cells.
Topics: Buthionine Sulfoximine; Carmustine; Cells, Cultured; Dinitrochlorobenzene; Epithelial Cells; Gene Expression Regulation, Enzymologic; Glutaredoxins; Glutathione; Humans; Hydrogen Peroxide; Lens, Crystalline; Oxidative Stress; Oxidoreductases; Protein Disulfide Reductase (Glutathione); Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Up-Regulation | 2001 |
Induction of mild intracellular redox imbalance inhibits proliferation of CaCo-2 cells.
Topics: Acetylcysteine; Buthionine Sulfoximine; Caco-2 Cells; Carmustine; Cell Division; Cell Survival; Cytoplasm; Diamide; Epidermal Growth Factor; Glutathione; Glutathione Disulfide; Humans; Kinetics; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Sulfhydryl Reagents | 2001 |
Influence of antioxidant depletion on nitrergic relaxation in the pig gastric fundus.
Topics: Aminoquinolines; Animals; Benzoates; Buthionine Sulfoximine; Carmustine; Chelating Agents; Ditiocarb; Enzyme Inhibitors; Ethacrynic Acid; Gastric Fundus; Glutathione; Hydroxocobalamin; Imidazoles; Immunohistochemistry; In Vitro Techniques; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Superoxide Dismutase; Swine; Thiolester Hydrolases; Ubiquitin Thiolesterase; Vasodilation | 2002 |
Inhibition of glutathione-related enzymes augments LPS-mediated cytokine biosynthesis: involvement of an IkappaB/NF-kappaB-sensitive pathway in the alveolar epithelium.
Topics: Animals; Antimetabolites; Blotting, Western; Buthionine Sulfoximine; Carmustine; Cytokines; Electrophoretic Mobility Shift Assay; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Female; Glutamate-Cysteine Ligase; Glutathione; Homeostasis; Lipopolysaccharides; NF-kappa B; Oxidation-Reduction; Pregnancy; Protein Disulfide Reductase (Glutathione); Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Signal Transduction; Sulfhydryl Compounds; Translocation, Genetic | 2002 |
Development of an in vitro chemo-radiation response assay for cervical carcinoma.
Topics: Antineoplastic Agents; Buthionine Sulfoximine; Carcinoma, Squamous Cell; Carmustine; Cell Division; Cisplatin; Combined Modality Therapy; Dose-Response Relationship, Radiation; Drug Screening Assays, Antitumor; Female; Humans; Paclitaxel; Pilot Projects; Radiation Tolerance; Radiation-Sensitizing Agents; Tumor Cells, Cultured; Uterine Cervical Neoplasms | 2002 |
Fructose-1,6-bisphosphate preserves intracellular glutathione and protects cortical neurons against oxidative stress.
Topics: Animals; Buthionine Sulfoximine; Carmustine; Cell Hypoxia; Cell Survival; Cells, Cultured; Cerebral Cortex; Enzyme Inhibitors; Free Radicals; Fructosediphosphates; Glutathione; Glutathione Reductase; Intracellular Fluid; Mice; Molsidomine; Neurons; Neuroprotective Agents; Nitric Oxide; Oxidation-Reduction; Oxidative Stress; Tetrazolium Salts; Thiazoles | 2003 |
Synthesis and antifilarial evaluation of N1,Nn- xylofuranosylated diaminoalkanes.
Topics: Alkanes; Animals; Antiparasitic Agents; Brugia malayi; Buthionine Sulfoximine; Carmustine; Cattle; Diamines; Enzyme Inhibitors; Female; Filarioidea; Glutamate-Cysteine Ligase; Glutathione; Glutathione Reductase; Glutathione Transferase; Male; Microfilariae; Rodentia; Vitamin K 3; Xylose | 2003 |
Regulation of glutathione in cardiac myocytes.
Topics: Animals; Antineoplastic Agents, Alkylating; Blood Pressure; Buthionine Sulfoximine; Carmustine; Drug Interactions; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Glutamate-Cysteine Ligase; Glutathione; Glutathione Reductase; Heart Rate; Heart Ventricles; Male; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Time Factors | 2003 |
Differential effects of glucose deprivation on the cellular sensitivity towards photodynamic treatment-based production of reactive oxygen species and apoptosis-induction.
Topics: Apoptosis; Buthionine Sulfoximine; Carmustine; Cell Line, Tumor; Culture Media; Glucose; Glutathione; Humans; Photochemotherapy; Photosensitizing Agents; Reactive Oxygen Species | 2005 |
Involvement of NF-kappaB and glutathione in cytotoxic effects of nitric oxide and taxol on human leukemia cells.
Topics: Buthionine Sulfoximine; Carmustine; Cell Line, Tumor; Glutathione; Humans; Leukemia; NF-kappa B; Nitric Oxide; Paclitaxel; Proline; S-Nitroso-N-Acetylpenicillamine; Thiocarbamates | 2006 |
Redox control of K+ channel remodeling in rat ventricle.
Topics: Animals; Blotting, Western; Buthionine Sulfoximine; Carmustine; Enzyme Inhibitors; Glutathione; Male; Microscopy, Confocal; Myocytes, Cardiac; Oxidation-Reduction; Patch-Clamp Techniques; Potassium Channels; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thioredoxins; Ventricular Remodeling | 2006 |
Schisandrin B-induced increase in cellular glutathione level and protection against oxidant injury are mediated by the enhancement of glutathione synthesis and regeneration in AML12 and H9c2 cells.
Topics: Animals; Antifibrinolytic Agents; Antineoplastic Agents, Alkylating; Buthionine Sulfoximine; Carmustine; Cyclooctanes; Cysteine; Cytoprotection; Enzyme Inhibitors; Glutamate-Cysteine Ligase; Glutathione; Glutathione Reductase; L-Lactate Dehydrogenase; Lignans; Mice; Oxidants; Oxidation-Reduction; Polycyclic Compounds; Vitamin K 3 | 2006 |
The interaction of chromium (VI) with macrophages: depletion of glutathione and inhibition of glutathione reductase.
Topics: Animals; Buthionine Sulfoximine; Carmustine; Catalase; Cell Line; Cell Survival; Chromium; Glutathione; Glutathione Disulfide; Glutathione Reductase; Macrophages; Mice; Superoxide Dismutase | 2007 |
Hypoxic remodelling of Ca2+signalling in SH-SY5Y cells: influence of glutathione.
Topics: Bradykinin; Buthionine Sulfoximine; Calcium Signaling; Carmustine; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutathione; Humans; Hypoxia; Neuroblastoma | 2007 |
Phenol-induced in vivo oxidative stress in skin: evidence for enhanced free radical generation, thiol oxidation, and antioxidant depletion.
Topics: Animals; Antioxidants; Buthionine Sulfoximine; Carmustine; Cell Line; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Female; Free Radicals; Glutathione; Interleukin-1; Mice; Mice, Inbred Strains; Oxidative Stress; Phenol; Skin; Sulfhydryl Compounds; Vitamin E | 2007 |
Protective mechanism of quercetin and rutin using glutathione metabolism on HO-induced oxidative stress in HepG2 cells.
Topics: Amitrole; Antioxidants; Apoptosis; Buthionine Sulfoximine; Carmustine; Catalase; Cell Line, Tumor; Cell Survival; Chelating Agents; Copper; Dose-Response Relationship, Drug; Glutathione; Humans; Hydrogen Peroxide; Oxidative Stress; Quercetin; Reactive Oxygen Species; Rutin | 2009 |
Imaging in real-time with FRET the redox response of tumorigenic cells to glutathione perturbations in a microscale flow.
Topics: Animals; Bacterial Proteins; Biosensing Techniques; Buthionine Sulfoximine; Carmustine; Cell Line, Transformed; Cell Tracking; CHO Cells; Cricetinae; Cricetulus; Diamide; Fibroblasts; Fluorescence Resonance Energy Transfer; Glutathione; Glutathione Disulfide; Green Fluorescent Proteins; Kinetics; Luminescent Proteins; Microfluidic Analytical Techniques; Microscopy, Confocal; Microscopy, Fluorescence; Oxidation-Reduction; Oxidative Stress; Recombinant Proteins; Swine; Transfection | 2011 |
The diverse roles of glutathione-associated cell resistance against hypericin photodynamic therapy.
Topics: Anthracenes; Breast Neoplasms; Buthionine Sulfoximine; Carmustine; Cell Line, Tumor; Drug Resistance, Neoplasm; Female; Glutathione; Glutathione Peroxidase; Glutathione S-Transferase pi; Humans; MCF-7 Cells; Perylene; Phospholipid Hydroperoxide Glutathione Peroxidase; Photochemotherapy | 2017 |