buthionine sulfoximine has been researched along with 4-hydroxy-2-nonenal in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (27.78) | 18.2507 |
| 2000's | 10 (55.56) | 29.6817 |
| 2010's | 3 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Malcolm, RR; Roberts, RJ; Spitz, DR; Sullivan, SJ | 1 |
| Kinter, MT; Roberts, RJ; Spitz, DR | 1 |
| Fukuda, A; Hitomi, K; Osawa, T; Uchida, K | 1 |
| Maher, JJ; Neuschwander-Tetri, BA | 1 |
| Hirabayashi, Y; Irie, F | 1 |
| de Vries, EE; Hooiveld, GJ; Jansen, PL; Krikken, I; Müller, M; Renes, J | 1 |
| Mizuno, M; Nabeshima, T; Nakajima, A; Yamada, K; Yan, Y; Zou, LB | 1 |
| Cao, Z; Hardej, D; Li, Y; Trombetta, LD | 1 |
| Irie, K; Maru, Y; Muraki, T; Ohba, K; Uchida, Y; Yoshioka, T | 1 |
| Bai, J; Cederbaum, AI | 1 |
| Hales, BF; Yan, J | 1 |
| Niki, E; Nishio, K; Noguchi, N; Numakawa, Y; Ogawa, Y; Saito, Y; Yoshida, Y | 1 |
| Aoki, R; Numazawa, S; Sakaguchi, H; Taira, T; Yoshida, T | 1 |
| Armstrong, DW; Awasthi, S; Awasthi, YC; Bae, S; Dent, P; Sharma, R; Singhal, J; Singhal, SS; Suzuki, S; Warnke, MM; Yacoub, A; Yadav, S | 1 |
| Douki, T; Falletti, O | 1 |
| Asano, N; Iijima, K; Kato, K; Kusaka, G; Shimosegawa, T; Uno, K | 1 |
| Sato, K; Takahashi, K; Tampo, Y; Tatsunami, R | 1 |
| Aykin-Burns, N; Banerjee, S; Hauer-Jensen, M; Krager, KJ; Melnyk, SB; Pawar, SA; Shah, SK | 1 |
18 other study(ies) available for buthionine sulfoximine and 4-hydroxy-2-nonenal
| Article | Year |
|---|---|
Glutathione dependent metabolism and detoxification of 4-hydroxy-2-nonenal.
Topics: Aldehydes; Animals; Buthionine Sulfoximine; Cell Line; Cell Survival; Cricetinae; Cricetulus; Glutathione; Glutathione Transferase; Inactivation, Metabolic; Kinetics; Methionine Sulfoximine | 1991 |
Contribution of increased glutathione content to mechanisms of oxidative stress resistance in hydrogen peroxide resistant hamster fibroblasts.
Topics: Aldehydes; Animals; Antimetabolites; Buthionine Sulfoximine; Cell Line; Cell Survival; Cricetinae; Cricetulus; Fibroblasts; Glutathione; Hydrogen Peroxide; Methionine Sulfoximine; Oxidative Stress | 1995 |
4-Hydroxy-2-nonenal cytotoxicity in renal proximal tubular cells: protein modification and redox alteration.
Topics: Acetylcysteine; Aldehydes; Animals; Buthionine Sulfoximine; Cell Line; Cell Survival; Cell-Free System; Glutathione; Glyceraldehyde-3-Phosphate Dehydrogenases; Kidney Tubules, Proximal; Kinetics; Muscle, Skeletal; Oxidation-Reduction; Proteins; Rabbits; Rats; Time Factors | 1996 |
Manipulation of glutathione stores in rat hepatic stellate cells does not alter collagen synthesis.
Topics: Aldehydes; Animals; Ascorbic Acid; Buthionine Sulfoximine; Cell Survival; Cells, Cultured; Collagen; Cross-Linking Reagents; Ferric Compounds; Glutathione; Hydrogen Peroxide; Kinetics; Liver; Male; Rats; Rats, Sprague-Dawley; Time Factors | 1997 |
Ceramide prevents motoneuronal cell death through inhibition of oxidative signal.
Topics: Aldehydes; Animals; Antioxidants; Buthionine Sulfoximine; Cell Death; Cell Survival; Cells, Cultured; Ceramides; Dose-Response Relationship, Drug; Embryo, Mammalian; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Glial Cell Line-Derived Neurotrophic Factor; Glutathione; Immunohistochemistry; Lipid Peroxidation; Motor Neurons; Nerve Growth Factors; Nerve Tissue Proteins; Neuroprotective Agents; Oxidation-Reduction; Rats; Rats, Wistar; Reactive Oxygen Species; Signal Transduction; Tyrosine | 1999 |
Multidrug resistance protein MRP1 protects against the toxicity of the major lipid peroxidation product 4-hydroxynonenal.
Topics: Adenosine Triphosphate; Aldehydes; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Biological Transport; Buthionine Sulfoximine; Carcinoma, Small Cell; Cell Line; Cell Survival; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutathione; Humans; Immunoblotting; Insecta; Kinetics; Leukotriene Antagonists; Lipid Peroxidation; Lung Neoplasms; Multidrug Resistance-Associated Proteins; Oxidative Stress; Propionates; Quinolines; Recombinant Proteins; Time Factors; Tumor Cells, Cultured | 2000 |
Interleukin-6 protects PC12 cells from 4-hydroxynonenal-induced cytotoxicity by increasing intracellular glutathione levels.
Topics: Aldehydes; Animals; Buthionine Sulfoximine; Cell Survival; DNA Primers; Enzyme Inhibitors; Glutamate-Cysteine Ligase; Glutathione; Growth Inhibitors; Humans; Hydrogen-Ion Concentration; Interleukin-1; Interleukin-2; Interleukin-6; Neuroprotective Agents; Oxidative Stress; PC12 Cells; Rats; Reverse Transcriptase Polymerase Chain Reaction | 2002 |
The role of chemically induced glutathione and glutathione S-transferase in protecting against 4-hydroxy-2-nonenal-mediated cytotoxicity in vascular smooth muscle cells.
Topics: Aldehydes; Animals; Antineoplastic Agents; Aorta; Buthionine Sulfoximine; Cell Survival; Cells, Cultured; Chemoprevention; Dose-Response Relationship, Drug; Enzyme Induction; Glutathione; Glutathione Transferase; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Rats; Sulfasalazine; Thiones; Thiophenes | 2003 |
Cellular carbonyl stress enhances the expression of plasminogen activator inhibitor-1 in rat white adipocytes via reactive oxygen species-dependent pathway.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Adipocytes; Aldehydes; Animals; Antioxidants; Buthionine Sulfoximine; Cells, Cultured; Deoxyguanosine; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Free Radical Scavengers; Glycation End Products, Advanced; Lipid Peroxidation; Male; NF-kappa B; Oxidative Stress; Plasminogen Activator Inhibitor 1; Rats; Rats, Inbred OLETF; Reactive Oxygen Species; RNA, Messenger; Up-Regulation | 2004 |
Overexpression of CYP2E1 in mitochondria sensitizes HepG2 cells to the toxicity caused by depletion of glutathione.
Topics: Aldehydes; Animals; Antioxidants; Blotting, Western; Buthionine Sulfoximine; Catalysis; Cell Line; Cell Survival; Cyclosporine; Cytochrome P-450 CYP2E1; DNA, Complementary; Endoplasmic Reticulum; Ethanol; Flow Cytometry; Glutathione; Humans; Liver; Liver Diseases, Alcoholic; Male; Membrane Potentials; Microscopy, Confocal; Mitochondria; Mitochondria, Liver; Oxidative Stress; Plasmids; Rats; Rats, Sprague-Dawley; Subcellular Fractions; Time Factors; Transfection; Tyrosine | 2006 |
Depletion of glutathione induces 4-hydroxynonenal protein adducts and hydroxyurea teratogenicity in the organogenesis stage mouse embryo.
Topics: Abnormalities, Drug-Induced; Aldehydes; Animals; Buthionine Sulfoximine; DNA; Embryo, Mammalian; Female; Glutathione; Hydroxyurea; Mice; Oxidative Stress; Pregnancy; Proto-Oncogene Proteins c-fos; Transcription Factor AP-1 | 2006 |
Protective effects of 15-deoxy-Delta12,14-prostaglandin J2 against glutamate-induced cell death in primary cortical neuron cultures: induction of adaptive response and enhancement of cell tolerance primarily through up-regulation of cellular glutathione.
Topics: Aldehydes; Animals; Buthionine Sulfoximine; Cell Death; Cells, Cultured; Cerebral Cortex; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Embryo, Mammalian; Enzyme Inhibitors; Glutamic Acid; Glutathione; Immunologic Factors; Neurons; Prostaglandin D2; Rats; Time Factors; Up-Regulation | 2007 |
Regulation of the susceptibility to oxidative stress by cysteine availability in pancreatic beta-cells.
Topics: Acetylcysteine; Aldehydes; Amino Acid Transport System y+; Animals; Animals, Newborn; Biological Transport; Buthionine Sulfoximine; Cell Line; Cell Line, Tumor; Cell Nucleus; Cell Survival; Cells, Cultured; Cysteine; Fibroblasts; Gene Expression; Glutathione; Homeodomain Proteins; Humans; Hydrogen Peroxide; Insulin-Secreting Cells; Kinetics; Oxidative Stress; Protein Transport; Rats; Rats, Wistar; Trans-Activators | 2008 |
RLIP76 in defense of radiation poisoning.
Topics: Aldehydes; Amifostine; Animals; ATP-Binding Cassette Transporters; Buthionine Sulfoximine; Fibroblasts; Glutathione; GTPase-Activating Proteins; Humans; JNK Mitogen-Activated Protein Kinases; Liposomes; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinase Kinases; Proto-Oncogene Proteins c-akt; Radiation Dosage; Radiation Tolerance; Radiation-Protective Agents; Tumor Stem Cell Assay | 2008 |
Low glutathione level favors formation of DNA adducts to 4-hydroxy-2(E)-nonenal, a major lipid peroxidation product.
Topics: Aldehydes; Buthionine Sulfoximine; Cell Survival; Cells, Cultured; Chromatography, High Pressure Liquid; DNA Adducts; Glutathione; Humans; Lipid Peroxidation; Monocytes; Tandem Mass Spectrometry | 2008 |
The balance between 4-hydroxynonenal and intrinsic glutathione/glutathione S-transferase A4 system may be critical for the epidermal growth factor receptor phosphorylation of human esophageal squamous cell carcinomas.
Topics: Acetylcysteine; Aged; Aldehydes; Antimetabolites; Blotting, Western; Buthionine Sulfoximine; Carcinoma, Squamous Cell; Cell Line, Tumor; ErbB Receptors; Esophageal Neoplasms; Female; Gene Expression Regulation, Neoplastic; Glutathione; Glutathione Transferase; Humans; Immunohistochemistry; Male; Phosphorylation; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction; Transfection; Tyrphostins | 2011 |
Multidrug resistance associated protein 1 together with glutathione plays a protective role against 4-hydroxy-2-nonenal-induced oxidative stress in bovine aortic endothelial cells.
Topics: Aldehydes; Animals; Aorta; Buthionine Sulfoximine; Cattle; Cell Death; Cell Survival; Endothelial Cells; Endothelium, Vascular; Glutathione; Multidrug Resistance-Associated Proteins; Oxidative Stress | 2012 |
Loss of C/EBPδ enhances IR-induced cell death by promoting oxidative stress and mitochondrial dysfunction.
Topics: Acetylcysteine; Adenosine Triphosphate; Aldehydes; Animals; Apoptosis; Buthionine Sulfoximine; Catalase; CCAAT-Enhancer-Binding Protein-delta; DNA; DNA Breaks, Double-Stranded; Dose-Response Relationship, Radiation; Embryo, Mammalian; Fibroblasts; Gamma Rays; Gene Expression Regulation; Glutathione; Mice; Mice, Knockout; Mitochondria; Oxidative Stress; Polyethylene Glycols; Primary Cell Culture; Reactive Oxygen Species; Signal Transduction; Superoxide Dismutase | 2016 |