Page last updated: 2024-08-21

butenolide and 4-butyrolactone

butenolide has been researched along with 4-butyrolactone in 331 studies

Research

Studies (331)

TimeframeStudies, this research(%)All Research%
pre-199018 (5.44)18.7374
1990's20 (6.04)18.2507
2000's97 (29.31)29.6817
2010's152 (45.92)24.3611
2020's44 (13.29)2.80

Authors

AuthorsStudies
Bourguignon, JJ; Charlier, B; Hechler, V; Maitre, M; Schmitt, M; Schoenfelder, A; Wermuth, CG1
Feron, VJ; Immel, HR; Kruysse, A; Til, HP1
Ito, M; Iwashima, A; Nishino, H; Satomi, Y; Tamai, Y; Torihara, M1
Snead, OC1
Aono, T; Azuma, K; Irahara, M; Kanematsu, T; Shitsukawa, K1
Arai, I; Muramatsu, M; Oomura, Y; Otomo, S; Shiraishi, T; Usuki-Ito, C1
Fukuda, M; Kobayashi, T; Nakamura, K; Ono, T1
Aihara, H; Chaki, S; Muramatsu, M1
Niijima, A1
Bhavanishankar, TN; Ramesh, HP; Shantha, T1
el-Basiouny, AA; el-Kousy, SM; el-Torgoman, AM; Hashem, AI1
Fukuda, A; Ito, C; Minami, T; Oomura, Y; Plata-Salamán, CR1
Oomura, Y; Plata-Salamán, CR; Shimizu, N1
Mester, Z; Reisch, J1
Némoz, G; Pacheco, H; Picq, M; Prigent, AF1
Lafont, J; Lafont, P; Romand, A1
Burmeister, HR; Grove, MD; Kwolek, WF1
Aou, S; Oomura, Y1
Fukui, Y; Hisano, S; Miki, T; Uemura, N; Zhang, R1
Fukui, Y; Hisano, S; Miki, M; Uemura, N; Zhang, R1
Braun, D; Pauli, N; Séquin, U; Zähner, H1
Ramírez, C; Rodríguez, AD1
Aikawa, T; Aou, S; Matsumoto, I; Nemoto, S; Nishino, H; Oomura, Y1
Imai, H; Kurimoto, Y; Morita, S; Naiki, M; Suehiro, S; Taguchi, N; Takeoka, Y1
Aono, T; Irahara, M; Matsuzaki, T; Saito, S; Shitsukawa, K1
Gasdorf, H; Peterson, RE; Vesonder, RF1
Gershwin, ME; Kurimoto, Y; Naiki, M; Suehiro, S; Takeoka, Y; Yago, H1
Manchanda, SK; Mathur, R; Nayar, U; Oomura, Y1
Fukui, Y; Hisano, S; Uemura, N1
Cain, RB; Fortnagel, P; Hebenbrock, S; Kirby, GW; McLenaghan, HJ; Rao, GV; Schmidt, S1
Aono, T; Irahara, M; Kaji, H; Saito, S; Shitsukawa, K1
He, M; Pei, W; Wang, P1
Tang, MH; Wu, Y; Wu, YL; Xia, LJ; Yu, Q1
Duan, D; Ma, S; Shi, Z1
Geisler, L; Hegedus, LS1
Eckardt, T; Langer, P; Stoll, M1
Kinoshita, T1
Helmke, E; Laatsch, H; Mukku, VJ; Speitling, M1
Davari, H; Hakimelahi, GH; Hakimelahi, S; Hwu, JR; King, KY; Mei, NW; Moosavi-Movahedi, AA; Wen, YS1
Beck, B; Dömling, A; Herdtweck, E; Magnin-Lachaux, M1
Iriye, R; Takai, K1
Aou, S; Hori, T; Li, AJ; Li, XL; Oomura, Y; Tooyama, I1
Ethiraj, KS; Hakimelahi, GH; Hakimelahi, S; Moosavi-Movahedi, AA; Pasdar, M; Sambaiah, T; Zhu, JL1
Dixon, DJ; Ley, SV; Reynolds, DJ1
Geisler, L; Hegedus, LS; Riches, AG; Salman, SS; Umbricht, G1
Brown, SP; Goodwin, NC; MacMillan, DW1
Greenberg, MM; Hashimoto, M; Kow, YW; Kroeger, KM1
Asakawa, Y; Hashimoto, T; Nukada, M; Quang, DN; Takaoka, S; Tanaka, M; Yamamoto, I1
Toste, FD; Trost, BM1
Alvarez-Larena, A; de March, P; Figueredo, M; Font, J; Piniella, JF; Raya, J1
Figadère, B; Franck, X; Hocquemiller, R; Jullian, JC; Latypov, S1
Li, S; Liu, HM; Zhang, F; Zhang, J1
Chamani, J; Hakimelahi, GH; Hakimelahi, S; Hassanzadeh, F; Jain, ML; Khodarahmi, GA; Kulatheeswaran, R; Luo, FT; Ly, TW; Moosavi-Movahedi, AA; Pasdar, M; Shia, KS; Xue, C; Yen, CF1
BOLTZE, KH; CHEMNITIUS, KH; HOFMANN, H1
CHEMNITIUS, KH; HOFMANN, H1
CHEMNITIUS, KH; DOSS, M; KARL, M1
GREGORY, H; GROS, EG; LEETE, E1
Aou, S; Matsumoto, I; Oomura, Y; Sakata, T1
Milius, W; Schobert, R; Stehle, R1
Dijkink, J; Fraanje, J; Goubitz, K; Guziec, FS; Hiemstra, H; Hue, BT; Kuiper, S; Larson, KK; Schenk, H; van Maarseveen, JH1
Harada, Y; Hashimoto, M; Morikawa, Y; Murakami, T; Okuno, T1
Ghisalberti, EL; Hargreaves, JR; McConville, E1
Casapullo, A; Gomez-Paloma, L; Monti, MC; Riccio, R1
Hashimoto, Y; Nagasawa, K; Sohtome, Y; Tanatani, A1
Ahmed, Z; Langer, P1
Ayuko, WO; Dunn, S; Kinchington, D; Lattmann, E; Singh, H; Tisdale, MJ1
Braun, M; Bühne, C; Grimme, S; Hohmann, A; Rahematpura, J1
MARRIAN, DH; RUSSELL, PB; TODD, AR1
Gallucci, J; Hilmey, DG; Kahane, AL; Paquette, LA; Seekamp, CK1
Cho, CW; Krische, MJ1
Adlington, RM; Bagal, SK; Baldwin, JE; Marquez, R1
Lu, L; Lu, P; Ma, S1
Brückner, R; Olpp, T1
Alvarez, R; Brückner, R; de Lera, AR; Vaz, B1
Adlington, RM; Baldwin, JE; Cowley, AR; Tchabanenko, K1
Brückner, R; Herzig, A; Kapferer, T; König, WA1
Fong, HH; Nguyen, MC; Nguyen, VH; Pezzuto, JM; Soejarto, DD; Tan, GT; Zhang, HJ1
Fuji, K; Kakiuchi, K; Morimoto, T; Tsutsumi, K1
Abarbri, M; Duchêne, A; Parrain, JL; Rousset, S; Thibonnet, J1
Fujita, Y; Ito, M; Mizuguchi, Y; Nakagawa, K; Okano, T; Yamano, Y; Yoshida, M1
Barluenga, J; de Prado, A; Santamaría, J; Tomás, M1
Itou, Y; Mori, S; Nishii, T; Shindo, M; Shishido, K; Yoshikawa, T1
Dallimore, JW; Robertson, J1
Norrby, PO; Rein, T; Strand, D1
Deyrup, ST; Gloer, JB; Sobolev, VS1
Fujihara, H; Hashimoto, H; Kawasaki, M; Mera, T; Nakamura, T; Ohnishi, H; Okimoto, N; Onaka, T; Saito, J; Ueta, Y; Yamaga, C1
Curran, DP; Gudipati, V; Wilcox, CS1
Kong, K; Romo, D1
Ghisalberti, EL; Lorito, M; Marra, R; Scala, F; Sivasithamparam, K; Vinale, F1
Alvarez, R; de Lera, AR; Domínguez, M; Vaz, B1
Cao, JL; Guo, X; Peng, SQ; Shi, ZL; Wang, SJ; Zhang, ZT; Zuo, H1
Aquino, M; Bruno, I; Gomez-Paloma, L; Riccio, R1
Carswell, EL; Hoveyda, AH; Snapper, ML1
Aurrecoechea, JM; de Torres, E; Suero, R1
Alexander, NJ; Blackwell, B; Desjardins, AE; Harris, LJ; Hattori, J; McCormick, SP; Ouellet, T; Piché, C; Robert, LS; Saparno, A; Schernthaner, JP; Tinker, N; Watson, R1
Fujihara, H; Hashimoto, H; Kawasaki, M; Nakamura, T; Ohnishi, H; Okimoto, N; Onaka, T; Otsubo, H; Saito, J; Suzuki, H; Ueta, Y1
Curran, TT; Das Sarma, K; Zhang, J1
Peng, SQ; Wang, GQ; Wang, MW; Wang, YM; Yan, CH; Yang, HY; Zhou, Q1
Andrews, SP; Ball, M; Ley, SV; Tait, MM1
Cao, JL; Guo, X; Peng, SQ; Ren, FL; Shi, ZL; Wang, SJ; Zhang, YG; Zhang, ZT1
Basabe, P; de la Iglesia-Vicente, J; Diez, D; Escola, MA; Marcos, IS; Mollinedo, F; Moro, RF; Sanz, F; Sierra, BG; Urones, JG1
Dong, YS; Han, G; Liu, JB; Peng, SQ; Wang, GQ; Wang, YM; Yan, CH; Yang, HY1
Liu, F; Patil, SN1
Rauter, AP; Xavier, NM2
Bäckvall, JE; Eriksson, L; Nyhlén, J1
Griffin, C; Larichev, V; McNulty, J; Pandey, S; Poloczek, J; Werstiuk, NH1
Gmeiner, P; Hahn, S; Kreis, W; Kuate, SP; Pádua, RM; Schebitz, PK; Waibel, R1
Matsunaga, S; Shibasaki, M; Yamaguchi, A1
Boto, A; Hernández, D; Hernández, R1
Ascough, GD; Jain, N; Van Staden, J1
Peng, SQ; Wang, HJ; Wang, YM3
Boukouvalas, J; Loach, RP1
Griggs, ND; Phillips, AJ1
Birkinshaw, C; Brodie, PJ; Cao, S; Kingston, DG; Miller, JS; Murphy, BT; Rakotobe, E; Rasamison, VE; Ratovoson, F; Suh, EM; Tendyke, K1
COCKER, W; HORNSBY, S1
Karunaratne, V; Macleod, JK; Ratnayake Bandara, BM; Ratnayake, R; Simmonds, P; Wijesundara, S1
Csákÿ, AG; Moreno, A; Navarro, C1
Cao, J; Chen, J; Li, S; Peng, S; Shi, Z; Yang, B; Zhang, Z1
Peng, SQ; Wang, YM; Yang, HY2
Deslongchamps, P; Phoenix, S; Reddy, MS; Zhang, H1
Feng, L; Li, XQ; Shao, ZH; Wei, MX; Zhou, XZ1
Crimmins, MT; Jacobs, DL1
Buchwald, SL; Hyde, AM1
Hirano, K; Miura, M; Mochida, S; Satoh, T1
Cafeo, G; De Rosa, M; Kohnke, FH; Soriente, A; Talotta, C; Valenti, L1
Burrows, J; Donohoe, TJ; Hargaden, GC; Harris, RM; Parker, J; Williams, O1
Bäckvall, JE; Deska, J1
Bull, JR; Caira, MR; Chibale, K; Stevens, AT1
Chen, CK; Lee, SS; Lin, YS1
Ma, S; Yu, Z1
Liu, JB; Peng, SQ; Wang, YM1
Dixon, KW; Flematti, GR; Ghisalberti, EL; Trengove, RD1
Alam, MM; Husain, A; Lal, S; Shaharyar, M1
Burger, BV; Kohout, L; Light, ME; Staerk, D; Van Staden, J1
Chen, S; Chen, YC; Cui, HL; Huang, JR; Lei, J; Wang, ZF; Wu, L1
Hong, GF; Liu, GZ; Liu, HM; Wu, Q; Xu, HW; Zhu, SL1
Cheng, T; Ge, Z; Li, R; Qi, C; Wang, J1
Caceres, A; Chen, Y; Huang, Y; Krunic, A; Mahady, GB; Michel, JL; Orjala, J; Perez, A; Soejarto, DD; Soni, KK; Veliz, M; Zhang, H1
Chainoy, R; Choowong, W; Kornsakulkarn, J; Nithithanasilp, S; Thongpanchang, C; Thongpanchang, T1
Challis, GL; Corre, C; Haynes, SW; Malet, N; Song, L1
Bugni, TS; Hentschel, U; Ireland, CM; Kozytska, S; Moll, H; Pimentel-Elardo, SM1
Ji, Y; Wang, W; Yu, C; Zhang, Y1
Arellano, SM; Qian, PY; Xiao, K; Xu, Y; Zhang, Y1
Aoki, K; Frank, HA; Iwashita, T; Kajikawa, T; Katsumura, S; Niedzwiedzki, DM1
Cheng, M; Hu, X; Ji, JX; Li, BG; Zhang, Q1
Mathur, R1
Feng, X; Lin, L; Liu, X; Shi, J; Yang, Y; Zhao, J; Zheng, K1
Huang, H; Jin, Z; Li, W; Liang, X; Wu, W; Ye, J; Yu, F1
Downes, KS; Lamont, BB; Light, ME; van Staden, J1
Hayakawa, M; Motohashi, K; Shin-ya, K; Takagi, M; Yamamura, H1
Boonyuen, N; Nuclear, P; Pudhom, K; Sommit, D1
Qian, PY; Wong, YH; Zhang, Y1
Matsuo, K; Shindo, M1
Pansare, SV; Paul, EK1
Feng, YF; Gao, H; Jiang, MM; Tang, JS; Yao, XS; Zhang, X1
Imhoff, JF; Ohlendorf, B; Schmaljohann, R; Schulz, D; Zinecker, H1
Fañanás-Mastral, M; Feringa, BL; Fletcher, SP; Geurts, K; Mao, B; Minnaard, AJ; van Zijl, AW1
Alexakis, A; Lefranc, A; Quintard, A1
Han, X; Huang, KW; Kwiatkowski, J; Lu, Y; Luo, J; Wang, H; Xu, LW1
Guo, LL; Guo, X; Liu, HM; Wang, XJ; Xu, B; Xu, HW; Zheng, CX; Zheng, JX1
Jia, X; Li, C; Li, J; Liu, Y1
Qian, PY; Sougrat, R; Wang, GC; Ying, X; Zhang, YF1
Feng, X; Lin, L; Liu, X; Xiao, X; Zhang, Q1
Deng, L; Singh, RP; Wu, Y1
Argade, NP; Patel, RM; Puranik, VG1
Chen, XL; Guo, YW; Li, J; Liu, HL; Xin, GR1
Abbandonato, G; Beltram, F; Bizzarri, R; Nifosì, R; Signore, G; Voliani, V1
Chandramouli, KH; Pan, K; Qian, PY; Wang, WX; Xiao, K; Xu, Y; Zhang, YF1
Buchta, V; Kuneš, J; Matoušová, E; Pour, M; Spulák, M; Tichotová, L; Votruba, I1
Guo, J; Huang, WP; Lin, BW; Peng, SQ; Shen, JL; Wang, YM; Wu, J; Yan, CH; Yuan, HT; Zhang, LS1
Arima, S; Ikeda, H; Kitani, S; Miyamoto, KT; Nagamitsu, T; Nihira, T; Takamatsu, S; Uchida, M1
Abarbri, M; Cherry, K; Commeiras, L; Duchêne, A; Héran, V; Inack Ngi, S; Parrain, JL; Thibonnet, J1
Dixon, KW; Flematti, GR; Nelson, DC; Scaffidi, A; Smith, SM; Sun, YK; Waters, MT1
He, L; Liu, C; Qian, PY; Xu, Y; Zhang, H; Zhang, YF1
Prasad, K; Prashad, M; Reddy, LR1
Aigle, B; Dickschat, JS; Leblond, P; Riclea, R; Schoenian, I; Spiteller, D1
Arakawa, K; Kinashi, H; Taniguchi, A; Tsuda, N1
Lin, W; Liu, D; Proksch, P; Shi, H; Van Ofwegen, L; Yu, S1
Flematti, GR; Scaffidi, A; Smith, SM; Waters, MT1
Han, Z; Jia, Y; Li, Y; Lin, W; Liu, L; Matsumura, K; Qian, PY; Xu, Y; Zhang, F1
Chen, W; Huang, KW; Jiang, Z; Lee, R; Qi, B; Tan, CH; Tan, D; Tong, G; Zhang, W1
Balázs, E; Kohout, L; Light, ME; Posta, M; Sebestyén, E; Soós, V; Van Staden, J1
Manna, MS; Mukherjee, S1
Kang, H; Kim, H; Nam, SJ; Rho, BJ; Wang, W1
Andersen, RJ; Centko, RM; Miao, VP; Patrick, BO; Ramón-García, S; Taylor, T; Thompson, CJ1
Ashouriha, M; Balalaie, S; Bijanzadeh, HR; Rominger, F1
Chen, RZ; He, Y; Hou, L; Kang, Y; Kovach, A; Li, J; Li, S; Liu, Y; Melcher, K; Song, W; Wang, Y; Wu, ZS; Xie, C; Xu, HE; Xu, TH; Xu, Y; Yi, W; Zhang, C; Zhao, LH; Zhong, D; Zhou, XE1
Chabaud, L; Guillou, C; Jusseau, X; Retailleau, P1
Gao, H; Gu, Q; Guo, W; Li, D; Wang, Q; Wang, W; Zhang, L; Zhu, M; Zhu, T1
Han, F; Wang, L; Wang, R; Yang, D; Zhang, B; Zhao, D1
Agrawal, N; Dobhal, MP; Dobhal, S; Joshi, YC; Pareek, D; Sharma, MC1
Fox, JM; Li, Y; Xie, X1
Han, Z; He, F; He, LS; Matsumura, K; Qi, SH; Qian, PY; Qiu, JW; Sun, J; Xu, Y; Zhang, Y1
Jiang, Z; Liu, H; Wu, X; Xie, L; Yan, L1
Cheng, JP; Li, X; Song, C; Xue, XS; Yang, C; Yu, A1
Kumagai, N; Shibasaki, M; Takada, H; Yin, L1
Bao, J; He, F; Qi, SH; Shi, YM; Tu, ZC; Zhang, XY1
Austin, CA; Burgos-Morón, E; Calderón-Montaño, JM; López-Lázaro, M; Mateos, S; Orta, ML; Pastor, N1
Álvarez, R; de Lera, ÁR; Otero, L; Vaz, B1
Fukushima, Y; Namba, A; Nanamiya, R; Tadano, K; Takao, K; Yoshida, K1
Argade, NP; Deore, PS1
Deng, Z; Liang, Y; Liao, XJ; Xu, SH; Zhang, J1
Bolm, C; Frings, M; Pan, F; Schiffers, I; Thomé, I1
Garad, D; Jadhav, AP; Rao, VU; Singh, RP1
Au, DW; Chen, L; Gao, Z; Qian, PY; Xu, Y; Ye, R1
Huang, R; Jiang, Y; Li, YQ; Ma, KX; Wang, T; Wu, SH; Xie, XS1
Guo, L; He, CJ; He, YC; Liu, J; Liu, JL; Peng, C; Xiong, L; Yang, H; Zhou, QM1
Castillo, S; García, S; Heredia, N1
Duan, HY; Ma, J; Xiao, H; Yao, RS; Ye, J; Yuan, ZZ; Zhao, G1
Huang, J; Liao, S; Lin, X; Liu, J; Liu, Y; Wang, J; Wang, L; Wei, X; Yang, B; Zhou, X1
Adrian, J; Stark, CB1
Au, DW; Bajic, VB; Chen, L; Han, Z; Qian, PY; Sun, J; Wong, YH; Zhang, H1
Chen, L; Qian, PY; Wang, W; Xu, Y1
Gharpure, SJ; Nanda, LN; Shukla, MK1
Heugebaert, TS; Kappe, CO; Stevens, CV1
Kulkarni, MG; Kumari, A; Papenfus, HB; Pošta, M; Van Staden, J1
Albreht, A; Vovk, I; Zupančič, B1
Au, DW; Bajic, VB; Chen, L; Lam, PK; Qian, PY; Qiu, JW; Sun, J; Zhang, H; Zhang, W1
Alam, MS; Ali, Y; Bano, S; Dhulap, A; Haider, S; Hamid, H; Husain, A; Hussain, F; Kharbanda, C; Nazreen, S; Shafi, S1
Chinchansure, AA; Durge, A; Joshi, SP; Kulkarni, SS; Nawale, L; Said, MS; Sarkar, D; Wadhwani, A1
Campbell, CD; Joannesse, C; Morrill, LC; Philp, D; Smith, AD1
Fedorenko, V; Makitrinskyy, R; Mutenko, H; Ostash, B; Tsypik, O; Walker, S1
Hayashi, M; Nakamura, S; Yamaji, R1
Beck, ME; Gutbrod, O; Haas, M; Jeschke, P; Matthiesen, S; Nauen, R; Velten, R1
Chen, YC; Jiang, K; Li, C1
Elkhayat, ES; Ibrahim, SR; Mohamed, GA; Ross, SA1
Li, H; Ma, D; She, X; Xie, X; Xu, D; Zhao, G; Zhong, Z1
Brodie, PJ; Callmander, MW; Kingston, DG; Presley, CC; Rakotobe, E; Rakotondraibe, LH; Randrianaivo, R; Rasamison, VE1
Bayfield, MA; Campos, ML; Eberlin, MN; Ifa, DR; Perez, C; Tata, A1
Bai, J; Chen, G; Feng, BM; Hua, HM; Liu, B; Liu, F; Pei, YH; Sun, Y; Wang, HF; Zhang, LH; Zhao, YQ1
Bai, J; Guo, F; Hua, H; Li, Z; Pei, Y; Shao, M; Wang, H; Wang, K; Xu, X; Zhao, F1
Chen, L; Chung, CY; Jassey, A; Li, CL; Lin, CC; Lin, LT; Liu, CH; Wang, GH; Yen, MH1
Feng, ZM; Han, B; Jiang, JS; Li, L; Yang, YN; Zhang, PC; Zhang, X1
Badet-Denisot, MA; Bonhomme, S; Boyer, FD; Burger, M; Chory, J; Clavé, G; Cornu, D; de Saint Germain, A; Le Caer, JP; Pelissier, F; Pillot, JP; Rameau, C; Retailleau, P; Turnbull, C1
Atago, T; Iguchi, H; Ikeda, H; Kitani, S; Miyamoto, KT; Nihira, T; Sultan, SP1
Dömling, A; Dubin, G; Grudnik, P; Holak, TA; Jablonski, M; Kalinowska-Tluscik, J; Kubica, K; Madej, M; Musielak, B; Potempa, J; Surmiak, E; Tomala, MD; Twarda-Clapa, A; Zak, KM1
An, X; Chen, G; Chen, S; Hu, X; Li, S; Lin, B; Pei, Y; Wang, H1
Choi, H; Giri, AG; Hahn, D; Kang, H; Kim, H; Lee, J; Nam, SJ; Patil, RS; Sung, Y; Wang, W; Won, DH1
Corção, G; da Silva Campos, M; Meneghetti, KL; Otton, LM1
Phainuphong, P; Phongpaichit, S; Preedanon, S; Rukachaisirikul, V; Saithong, S; Sakayaroj, J; Sukpondma, Y; Tadpetch, K1
Mori, K; Namba, A; Nemoto, R; Ogura, A; Takao, KI; Yoshida, K1
Castle, SJ; Merten, P; Palumbo, JP1
Cembrowska-Lech, D; Kępczyński, J; Koprowski, M; Krawczyk, E; Wójcik, A1
Endo, N; Fukuda, Y; Kadota, I; Kikuchi, T; Ohashi, T; Takamura, H1
Acosta, JAM; Barbosa, LCA; Boukouvalas, J; Muddala, R1
Fañanás-Mastral, M; Feringa, BL; Mao, B1
Anderson, EA; Baars, H; Chaubet, G; Cordonnier, MA; Gockel, B; Goh, SS; Mohammad, M; Phillips, AW1
Hodgson, DM; Josa-Culleré, L; Ribaucourt, A; Thompson, AL; Towers, C; Willenbrock, F1
Ahmed, Y; Brötz, E; Luzhetskyy, A; Rebets, Y; Tokovenko, B1
Cen, S; Fang, XM; Liu, HY; Pang, X; Su, J; Yu, LY; Zhang, DW; Zhang, T; Zhao, JY1
Ebrahim, W; El-Neketi, M; Hartmann, R; Küppers, L; Kurtán, T; Lin, W; Liu, Z; Mándi, A; Müller, WEG; Orfali, RS; Özkaya, FC; Proksch, P; Song, W1
Gong, C; Hua, H; Li, L; Lin, H; Liu, J; Sun, Y; Wang, S; Yang, F1
Chiang, H; Ding, W; Ma, C; Qian, PY; Tam, C; Xu, Y; Zhang, G; Zhang, W1
Chen, KX; Guo, YW; Han, GY; Liang, LF; Sun, DY; Yao, LG1
Kitani, S; Nguyen, TB; Nihira, T; Shimma, S1
Bartlett, AJ; Brown, LR; de Solla, SR; Gillis, PL; Hedges, AM; Intini, KD; Maisonneuve, FJ; Robinson, SA2
Hung, CJ; Scharf, MJ; Trost, BM1
Chaipech, S; Ishikawa, F; Manse, Y; Marumoto, S; Morikawa, T; Muraoka, O; Ninomiya, K; Ogawa, T; Pongpiriyadacha, Y; Sonoda, N; Tanabe, G1
He, Y; Hu, Z; Li, F; Liu, M; Qi, C; Sun, W; Wang, J; Xue, Y; Zhang, J; Zhang, Y; Zhu, H1
Dubert, F; Dziurka, M; Kalandyk, A; Kopeć, P; Pastuszak, J; Płażek, A; Waligórski, P; Wolko, B1
Cuong, NX; Dang, NH; Hanh, TTH; Huong, PTT; Kiem, PV; Minh, CV; Nam, NH; Thanh, NV; Thung, DC; Vien, LT1
Chen, C; Gao, W; Hu, Z; Lai, Y; Li, D; Liu, M; Qi, C; Wang, J; Xue, Y; Zhang, J; Zhang, Q; Zhang, Y; Zhou, Q; Zhu, H1
Dibrell, SE; El Arba, M; Frantz, DE; Meece, F1
Li, H; Liao, G; Liu, L; Wei, X; Wu, P; Xue, J1
Li, D; Li, Y; Liu, X; Tan, H; Tian, Y; Wang, W; Zhang, J1
Chen, C; Gao, W; Guan, D; Hu, Z; Lai, Y; Liu, M; Qi, C; Wang, J; Zhang, Y; Zhou, Q; Zhou, Y; Zhu, H1
Capon, RJ; Khushi, S; Nahar, L; Salim, AA1
Chu, MJ; Han, X; Jiang, MM; Li, GQ; Li, PL; Li, T; Luo, LZ; Luo, XC; Tang, XL; van Ofwegen, L; Zhang, G1
Chen, XW; Chi, H; Gao, XW; Liang, PZ; Ma, KS; Tang, CY; Xia, J1
Hu, ZL; Liang, J; Xu, Y; Yin, Q; Zhang, L; Zhang, W; Zhang, Y1
Davies, JM; Guerringue, Y; Jamieson, FJC; Matthus, E; Swarbreck, SM1
Amaral, M; Andrade, CH; Antar, GM; Conserva, GAA; da Costa-Silva, TA; Lago, JHG; Neves, BJ; Tempone, AG1
Khuda, L; Khudyi, O; Kushniryk, O; Lubenets, V; Marchenko, M; Nakonechna, A; Novikov, V; Zvarych, V1
Fukumoto, K; Renzetti, A1
Bao, L; Cao, X; Ke, S; Song, D; Wang, J; Wang, S1
Kulkarni, M; Naidoo, D; Pošta, M; Roy, A; Van Staden, J1
Jiang, JR; Jing, L; Liu, DM; Sheng, JW; Tang, JB; Xia, GX; Zhang, WF1
Cheng, Z; Li, Q; Li, Y; Liu, J; Liu, L; Liu, W; Luo, Z; Xu, W; Yuan, W1
Bell, HC; Benavides, JE; Montgomery, CN; Navratil, JRE; Nieh, JC1
Du, SY; Fang, ZY; Zeng, Z; Zhou, J1
Huang, GJ; Kuo, TF; Kuo, YH; Liang, YC; Lu, TL; Tseng, HC; Tu, PC1
Minamino, K; Murata, M; Tsuchikawa, H1
Almanza, MT; Bass, C; Beadle, K; Exeler, N; Garside, C; Glaubitz, J; Hayward, A; Nauen, R; Nikolakis, A; Singh, KS; Zaworra, M1
Huang, H; Ju, J; Song, Y; Wang, X; Zang, R1
Lian, Y; Wang, C; Yang, T1
Chowdhury, S; Klapper, M; Menzel, KD; Paschold, A; Rosenbaum, MA; Schlabach, K; Stallforth, P; Zhang, S1
Jiang, ZH; Li, DC; Liao, XJ; Xu, SH; Yang, Y; Zhang, B; Zhao, BX1
Dai, LY; Huang, MN; Li, G; Liu, L; Qiu, JK; Yin, QM; Zhang, ZY1
Chiang, HY; Ma, C; Pan, J; Qian, PY1
Bracegirdle, J; Keyzers, RA1
Choi, JH; D Alessandro-Gabazza, CN; Gabazza, EC; Harada, E; Hirai, H; Kawagishi, H; Ridwan, AY; Toda, M; Wu, J; Yasuma, T1
Fu, J; Hammoud, S; Kremer, L; Maaliki, C; Raynaud, C; Thibonnet, J; Thiery, E; Viljoen, A; Villaume, S; Vincent, SP1
Bishop, CA; Common, J; Elliott, JE; Maisonneuve, F; Moran, AJ; Woundneh, MB1
Dose, B; Flórez, LV; Hertweck, C; Ishida, K; Kaltenpoth, M; Kumpfmüller, J; Little, RF; Niehs, SP1
Dastager, SG; Gajbhiye, J; Khan, A; Kumar, P; Nayak, R; Sahu, AK; Said, MS; Udavant, R1
Deng, M; Qi, C; Qiao, Y; Shi, Z; Sun, W; Tao, L; Xie, S; Zhang, Y1
Arakawa, K; Hadae, N; Teshima, A; Tsuda, N1
Bai, K; Fan, C; He, J; Hong, B; Le, Q; Niu, S; Tang, C; Xiao, M1
Harder, T; Tebben, J; Tillmann, U; Zurhelle, C1
Challis, GL; Corre, C; Malet, NR; Song, L; Zhou, S1
Flematti, GR; Khosla, A; Komatsu, A; Kyozuka, J; Melville, KT; Meng, Y; Nelson, DC; Scaffidi, A; Waters, MT; Yao, J1
Bao, J; He, F; Li, XX; Wang, YY; Yu, JH; Zhang, H; Zhang, X; Zhu, K1
Fang, J; Ge, Y; Gu, Z; Hou, D; Liu, H; Liu, L; Luo, J; Mao, L; Tan, Y; Wang, Z; Wei, Z; Xu, H1
Chen, G; Chen, X; Deng, M; Lu, Y; Qi, C; Qiao, Y; Shi, Z; Tan, X; Xie, S; Zhang, Y1
Almanza, MT; Bass, C; Davies, TGE; Glaubitz, J; Haas, J; Hertlein, G; Kohler, M; Lagojda, A; Lueke, B; Maus, C; Nauen, R; Zaworra, M1
Abd El-Hameed, RH; Ali, SA; El-Shanbaky, HM; Mahgoub, S; Mohamed, MS1
El-Hameed, RHA; El-Shanbaky, HM; Mohamed, MS1
Shen, Q; Yin, C; Yu, C; Zheng, X; Zhong, T1
Baire, B; Roy, D; Tharra, P1
Cheng, X; Gutman, K; Li, T; Zhang, L1
Chen, J; Hu, D; Mou, H; Shi, J1
Ji, P; Meng, X; Wang, W; Yu, C; Zhang, Y1
Cheng, J; Chiang, HY; Liu, X; Ma, C; Qian, PY1
Chen, X; Gao, JM; Han, WB; Huo, GM; Li, JN; Lin, LB; Wei, J; Zhai, YJ; Zhang, Q1
Chekshin, N; Hu, L; Qian, S; Qiao, JX; Wang, Z; Yu, JQ; Zhuang, Z1
Garcia, R; Hug, JJ; Kjaerulff, L; Müller, R1
Chen, Q; Li, S; Yang, J; Zhang, J1
Baghdikian, B; Clerc, P; de Voogd, NJ; Dufossé, L; Fouillaud, M; Garayev, E; Gauvin-Bialecki, A; Greff, S; Herbette, G; Mabrouki, F; Ollivier, E; Ouazzani, J; Saïd Hassane, C; Trougakos, IP1
Li, J; Liu, X; Tan, H; Tian, Y; Wang, W; Zhang, J1
Fan, H; Lei, YH; Si-Tu, MX; Wei, X; Zhang, CX; Zhou, FG1
Amsler, CD; Baker, BJ; Bracegirdle, J; Kennedy, SJ; McClintock, JB; Shan, C; Shaw, LN; Wojtas, L1
Ai, YF; Dong, SH; Huang, XX; Lin, B; Song, SJ1
Bhupathiraju, NVSDK; Gonzalez Periche, P; Johnson, DS; Kalidindi, T; Mootoo, DR; Pillarsetty, N; Ramdular, A1
Song, XQ; Song, YL; You, ZH; Zou, S1
Chen, J; Shukla, D1
Li, DC; Liang, HX; Liao, XJ; Xing, XW; Xu, SH; Zhao, BX1

Reviews

10 review(s) available for butenolide and 4-butyrolactone

ArticleYear
[Role of miscellaneous substances (organic acids, lactone, etc) in regulation of food intake].
    Nihon rinsho. Japanese journal of clinical medicine, 1995, Volume: 53 Suppl

    Topics: 4-Butyrolactone; Animals; Eating; Fatty Acids; Furans; Humans; Lactones; Prostaglandins

1995
Physiological significance of 2-buten-4-olide (2-B4O), an endogenous satiety substance increased in the fasted state.
    Experimental biology and medicine (Maywood, N.J.), 2003, Volume: 228, Issue:10

    Topics: 4-Butyrolactone; Animals; Blood Glucose; Fasting; Furans; Hypothalamo-Hypophyseal System; Insulin; Mice; Neurons; Pituitary-Adrenal System; Rats; Rats, Inbred Lew; Satiety Response; Sugar Acids; Ventromedial Hypothalamic Nucleus

2003
Sugars containing alpha,beta-unsaturated carbonyl systems: synthesis and their usefulness as scaffolds in carbohydrate chemistry.
    Carbohydrate research, 2008, Jul-21, Volume: 343, Issue:10-11

    Topics: 4-Butyrolactone; Carbohydrates; Furans; Ketoses; Lactones; Pyrans

2008
Catalytic asymmetric synthesis of γ-butenolides by direct vinylogous reactions.
    Mini reviews in medicinal chemistry, 2013, May-01, Volume: 13, Issue:6

    Topics: 4-Butyrolactone; Alkenes; Catalysis; Chemistry Techniques, Synthetic; Coordination Complexes; Furans

2013
Flupyradifurone (Sivanto™) and its novel butenolide pharmacophore: Structural considerations.
    Pesticide biochemistry and physiology, 2015, Volume: 121

    Topics: 4-Butyrolactone; Animals; Insect Proteins; Insecticides; Molecular Docking Simulation; Molecular Structure; Nicotinic Agonists; Receptors, Nicotinic

2015
Catalytic Asymmetric Synthesis of Butenolides and Butyrolactones.
    Chemical reviews, 2017, Aug-09, Volume: 117, Issue:15

    Topics: 4-Butyrolactone; Catalysis; Lactones; Molecular Structure; Organometallic Compounds; Stereoisomerism

2017
Synthesis of Phthalides and α,β-butenolides by Transition Metal-Catalyzed Activation of C-H Bonds.
    Molecules (Basel, Switzerland), 2019, Feb-25, Volume: 24, Issue:4

    Topics: 4-Butyrolactone; Benzofurans; Catalysis; Coordination Complexes; Cycloaddition Reaction; Molecular Structure; Oxidation-Reduction; Transition Elements

2019
Comparing and Contrasting the Multiple Roles of Butenolide Plant Growth Regulators: Strigolactones and Karrikins in Plant Development and Adaptation to Abiotic Stresses.
    International journal of molecular sciences, 2019, Dec-12, Volume: 20, Issue:24

    Topics: 4-Butyrolactone; Adaptation, Biological; Furans; Lactones; Plant Development; Plant Growth Regulators; Plant Physiological Phenomena; Pyrans; Signal Transduction; Stress, Physiological; Structure-Activity Relationship

2019
Marine-derived Polyaromatic Butenolides - Isolation, Synthesis and Biological Evaluations.
    Current pharmaceutical design, 2020, Volume: 26, Issue:35

    Topics: 4-Butyrolactone; Aquatic Organisms; Biological Products; Humans

2020
γ-Aromatic Butenolides of Microbial Source - A Review of Their Structures, Biological Activities and Biosynthesis.
    Chemistry & biodiversity, 2022, Volume: 19, Issue:6

    Topics: 4-Butyrolactone; Biological Products; Lactones

2022

Other Studies

321 other study(ies) available for butenolide and 4-butyrolactone

ArticleYear
Analogues of gamma-hydroxybutyric acid. Synthesis and binding studies.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:5

    Topics: Animals; Binding Sites; Brain; Hydroxybutyrates; In Vitro Techniques; Rats; Structure-Activity Relationship

1988
Repeated exposure to butenolide vapour: subacute study in Syrian golden hamsters.
    Toxicology, 1979, Volume: 15, Issue:1

    Topics: 4-Butyrolactone; Animals; Behavior, Animal; Body Weight; Cricetinae; Environmental Exposure; Female; Furans; Male; Mesocricetus; Nasal Mucosa; Smoking; Time Factors

1979
Inhibitory effects of (1E,3E,5E,7E)-5-hydroxy-4-(8-phenyl-1,3,5,7- octatetraenyl)-2(5H)-furanone on proliferation of human malignant tumor cells.
    Anti-cancer drug design, 1992, Volume: 7, Issue:2

    Topics: 4-Butyrolactone; Antineoplastic Agents; Blotting, Northern; Carotenoids; Cell Division; DNA, Neoplasm; Flow Cytometry; Furans; Genes, myc; HeLa Cells; Humans; Neoplasm Proteins; Neuroblastoma; Pancreatic Neoplasms; RNA, Messenger; Stomach Neoplasms; Thymidine; Tumor Cells, Cultured

1992
Effect of gamma-crotonolactone in experimental models of generalized absence seizures.
    Brain research, 1991, Mar-08, Volume: 543, Issue:1

    Topics: 4-Butyrolactone; Animals; Anticonvulsants; Disease Models, Animal; Electroencephalography; Furans; Male; Pentylenetetrazole; Rats; Rats, Inbred Strains; Seizures; Sodium Oxybate; Time Factors

1991
Effect of 2-buten-4-olide, an endogenous suppressant of feeding, on reproductive function in rats.
    Acta endocrinologica, 1990, Volume: 123, Issue:5

    Topics: 4-Butyrolactone; Animals; Body Weight; Dose-Response Relationship, Drug; Estradiol; Estrus; Female; Furans; Gonadotropin-Releasing Hormone; Hypothalamus; Injections, Intraperitoneal; Luteinizing Hormone; Organ Size; Ovary; Pituitary Gland; Rats; Rats, Inbred Strains; Reproduction; Uterus

1990
Effect of an endogenous satiety substance, 2-buten-4-olide, on gastric acid secretion and experimental ulceration in rats.
    Physiology & behavior, 1990, Volume: 47, Issue:1

    Topics: 4-Butyrolactone; Animals; Cimetidine; Cysteamine; Deoxyglucose; Duodenal Ulcer; Famotidine; Furans; Gastric Acid; Male; Rats; Rats, Inbred Strains; Stimulation, Chemical; Stomach Ulcer; Stress, Physiological

1990
Central action of endogenous sugar acid (2-buten-4-olide): comparison with local anesthesia in hypothalamus.
    Brain research bulletin, 1990, Volume: 24, Issue:6

    Topics: 4-Butyrolactone; Action Potentials; Amygdala; Anesthetics; Animals; Avoidance Learning; Furans; Hypothalamic Area, Lateral; Male; Rats; Rats, Inbred Strains; Tegmentum Mesencephali

1990
Alteration of gastroduodenal acetylcholine metabolism induced by 2-deoxy-D-glucose in rats.
    Scandinavian journal of gastroenterology. Supplement, 1989, Volume: 162

    Topics: 4-Butyrolactone; Acetylcholine; Acetylcholinesterase; Animals; Choline; Choline O-Acetyltransferase; Deoxy Sugars; Deoxyglucose; Dose-Response Relationship, Drug; Duodenum; Furans; Gastric Acid; Gastric Mucosa; Male; Rats; Rats, Inbred Strains; Vagus Nerve

1989
The effect of endogenous sugar acids on the afferent discharge rate of the hepatic branch of the vagus nerve in the rat.
    Physiology & behavior, 1988, Volume: 44, Issue:4-5

    Topics: 4-Butyrolactone; Afferent Pathways; Animals; Blood Glucose; Furans; Hunger; Hydroxybutyrates; Liver; Male; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Vagus Nerve

1988
Dermal toxicity of Fusarium toxins in combinations.
    Archives of toxicology, 1988, Volume: 61, Issue:3

    Topics: 4-Butyrolactone; Animals; Drug Synergism; Furans; Guinea Pigs; Male; Mycotoxins; Sesquiterpenes; Skin; T-2 Toxin; Trichothecenes

1988
Synthesis and reactions of some delta beta,gamma-butenolides with a study of their biological activity.
    Die Pharmazie, 1988, Volume: 43, Issue:2

    Topics: 4-Butyrolactone; Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Chemical Phenomena; Chemistry; Furans; Microbial Sensitivity Tests; Yeasts

1988
A novel endogenous sugar acid depolarizes ventromedial hypothalamic neurons in vitro.
    The American journal of physiology, 1988, Volume: 255, Issue:1 Pt 2

    Topics: 4-Butyrolactone; Animals; Dose-Response Relationship, Drug; Electrophysiology; Furans; Male; Membrane Potentials; Neurons; Rats; Rats, Inbred Strains; Ventromedial Hypothalamic Nucleus

1988
Endogenous sugar acid derivative acting as a feeding suppressant.
    Physiology & behavior, 1986, Volume: 38, Issue:3

    Topics: 4-Butyrolactone; Animals; Body Weight; Drinking Behavior; Feeding Behavior; Furans; Injections, Intraperitoneal; Injections, Intraventricular; Intubation, Gastrointestinal; Male; Motor Activity; Rats; Rats, Inbred Strains

1986
[A one-step process for the preparation of gamma-ylidene-alpha,beta-butenolides].
    Archiv der Pharmazie, 1985, Volume: 318, Issue:5

    Topics: 4-Butyrolactone; Aldehydes; Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Furans; Leukemia P388; Mice

1985
Selective inhibition of separated forms of cyclic nucleotide phosphodiesterase from rat heart by some cardio- or vaso-active butenolide derivatives.
    Biochemical pharmacology, 1982, Nov-01, Volume: 31, Issue:21

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 4-Butyrolactone; Animals; Benzofurans; Benzoin; Cytosol; Furans; Isoenzymes; Myocardium; Phosphodiesterase Inhibitors; Purinones; Rats; Vasodilator Agents

1982
[Effect of mycotoxins on the rate of fermentation in Saccharomyces cerevisiae].
    Mycopathologia, 1981, May-08, Volume: 74, Issue:2

    Topics: 4-Butyrolactone; Aflatoxin B1; Aflatoxins; Fermentation; Furans; Mycotoxins; Penicillic Acid; Saccharomyces cerevisiae; T-2 Toxin; Trichothecenes

1981
Moniliformin and butenolide: effect on mice of high-level, long-term oral intake.
    Applied and environmental microbiology, 1980, Volume: 40, Issue:6

    Topics: 4-Butyrolactone; Animals; Body Weight; Cyclobutanes; Furans; Fusarium; Lethal Dose 50; Mice; Mycotoxins

1980
Region-related Fos expression in hypothalamic dopaminergic neurons of rats by intraperitoneal administration of an endogenous satiety substance, 2-buten-4-olide.
    Brain research, 1995, Apr-10, Volume: 676, Issue:2

    Topics: 4-Butyrolactone; Animals; Dopamine; Furans; Hypothalamus; Immunohistochemistry; Injections, Intraperitoneal; Male; Nerve Tissue Proteins; Neurons; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Satiety Response; Tyrosine 3-Monooxygenase

1995
Induction of Fos-like immunoreactivity in the rat hypothalamus by an endogenous feeding suppressant (2-buten-4-olide).
    Neuroscience letters, 1994, Nov-21, Volume: 182, Issue:1

    Topics: 4-Butyrolactone; Animals; Eating; Furans; Hypothalamus; Immunohistochemistry; Injections, Intraperitoneal; Male; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Tissue Distribution

1994
New butenolides from the photoconductivity screening of Streptomyces antibioticus (Waksman and Woodruff) Waksman and Henrici 1948.
    FEMS microbiology letters, 1995, Feb-01, Volume: 126, Issue:1

    Topics: 4-Butyrolactone; Anti-Bacterial Agents; Cell Extracts; Chromatography, High Pressure Liquid; Furans; Lactones; Streptomyces antibioticus

1995
Further butenolides from the Caribbean octocoral Pterogorgia citrina.
    Journal of natural products, 1994, Volume: 57, Issue:3

    Topics: 4-Butyrolactone; Animals; Cnidaria; Colonic Neoplasms; Drug Screening Assays, Antitumor; Escherichia coli; Furans; Humans; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Tumor Cells, Cultured

1994
Effects of 2-buten-4-olide, an endogenous satiety substance, on plasma glucose, corticosterone, and catecholamines.
    The American journal of physiology, 1994, Volume: 266, Issue:2 Pt 2

    Topics: 4-Butyrolactone; Analysis of Variance; Animals; Blood Glucose; Corticosterone; Dose-Response Relationship, Drug; Epinephrine; Furans; Injections, Intravenous; Kinetics; Male; Norepinephrine; Rats; Rats, Wistar; Satiation; Time Factors

1994
2-Buten-4-olide (2-B4O) inhibits type II collagen-induced arthritis in Lewis rats.
    International journal of immunopharmacology, 1993, Volume: 15, Issue:7

    Topics: 4-Butyrolactone; Animals; Antibody Formation; Arthritis, Rheumatoid; Arthrography; Collagen; Disease Models, Animal; Female; Furans; Hypersensitivity, Delayed; Rats; Rats, Inbred Lew

1993
Effects of 2-buten-4-olide, an endogenous feeding suppressant, on the pulsatile secretion of luteinizing hormone in ovariectomized rats.
    Acta endocrinologica, 1993, Volume: 129, Issue:5

    Topics: 4-Butyrolactone; Animals; Corticotropin-Releasing Hormone; Dose-Response Relationship, Drug; Female; Furans; Injections, Intraperitoneal; Injections, Intravenous; Injections, Intraventricular; Luteinizing Hormone; Ovariectomy; Peptide Fragments; Pituitary Gland; Radioimmunoassay; Rats; Rats, Wistar; Time Factors

1993
Comparison of the cytotoxicities of Fusarium metabolites and Alternaria metabolite AAL-toxin to cultured mammalian cell lines.
    Archives of environmental contamination and toxicology, 1993, Volume: 24, Issue:4

    Topics: 4-Butyrolactone; Alternaria; Animals; Cell Death; Cell Line; Cricetinae; Cyclobutanes; Furans; Fusaric Acid; Fusarium; Mice; Mycotoxins; Sphingosine; Tumor Cells, Cultured

1993
2-Buten-4-olide (2-B4O) inhibits experimental allergic encephalomyelitis (EAE) in Lewis rats.
    Journal of autoimmunity, 1995, Volume: 8, Issue:5

    Topics: 4-Butyrolactone; Animals; Encephalomyelitis, Autoimmune, Experimental; Female; Furans; Immunosuppressive Agents; Lymphocyte Activation; Myelin Basic Protein; Peptide Fragments; Rats; Rats, Inbred Lew; T-Lymphocytes

1995
2-buten 4 olide affects feeding behavior of rhesus monkey.
    Progress in neuro-psychopharmacology & biological psychiatry, 1996, Volume: 20, Issue:1

    Topics: 4-Butyrolactone; Animals; Behavior, Animal; Body Weight; Dose-Response Relationship, Drug; Feeding Behavior; Furans; Immunosuppressive Agents; Macaca mulatta; Male

1996
Induction of Fos-like immunoreactivity in the lower brainstem and the spinal cord of the rat by intraperitoneal administration of an endogenous satiety substance, 2-buten-4-olide.
    Neuroscience letters, 1997, May-16, Volume: 227, Issue:2

    Topics: 4-Butyrolactone; Animals; Brain Stem; Furans; Immunosuppressive Agents; Injections, Intravenous; Male; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Spinal Cord

1997
Biosynthesis of a cyclic tautomer of (3-methylmaleyl)acetone from 4-hydroxy-3,5-dimethylbenzoate by Pseudomonas sp. HH35 but not by Rhodococcus rhodochrous N75.
    Biochemical and biophysical research communications, 1997, Sep-08, Volume: 238, Issue:1

    Topics: 4-Butyrolactone; Benzoates; Biotransformation; Furans; Isomerism; Magnetic Resonance Spectroscopy; Maleates; Oxygen Consumption; Pseudomonas; Rhodococcus

1997
The endogenous feeding suppressant, 2-buten-4-olide, impairs the pulsatile secretion of luteinizing hormone through endogenous opioid peptides.
    European journal of endocrinology, 1998, Volume: 138, Issue:2

    Topics: 4-Butyrolactone; Animals; Appetite Depressants; Female; Furans; Luteinizing Hormone; Naloxone; Periodicity; Pro-Opiomelanocortin; Rats; Rats, Wistar; RNA, Messenger

1998
Mass spectrometric study of gamma-aryl-alpha,-gamma-diethoxy-alpha, beta-butenolides.
    Rapid communications in mass spectrometry : RCM, 2000, Volume: 14, Issue:1

    Topics: 4-Butyrolactone; Carbon Isotopes; Furans; Kinetics; Magnetic Resonance Spectroscopy; Protons; Spectrometry, Mass, Fast Atom Bombardment

2000
Base-catalyzed epimerization of the butenolide in annonaceous acetogenins.
    Chirality, 2000, Volume: 12, Issue:3

    Topics: 4-Butyrolactone; Catalysis; Circular Dichroism; Furans; Lactones; Stereoisomerism

2000
Palladium(0)-catalyzed cyclization reaction of polymer-supported aryl iodides with 1,2-allenyl carboxylic acids. A facile solid-phase synthesis of butenolides.
    Organic letters, 2000, May-18, Volume: 2, Issue:10

    Topics: 4-Butyrolactone; Alkenes; Carboxylic Acids; Catalysis; Drug Design; Furans; Iodides; Models, Molecular; Molecular Structure; Palladium; Structure-Activity Relationship

2000
Synthesis of (+)-neplanocin A from a chromium-carbene complex-derived optically active butenolide.
    The Journal of organic chemistry, 2000, Jun-30, Volume: 65, Issue:13

    Topics: 4-Butyrolactone; Adenosine; Antibiotics, Antineoplastic; Antiviral Agents; Furans; Indicators and Reagents; Molecular Conformation; Stereoisomerism

2000
Efficient synthesis of butenolide-medium ring ether hybrids by a [3 + 2] cyclization-ring-closing metathesis strategy.
    Organic letters, 2000, Sep-21, Volume: 2, Issue:19

    Topics: 4-Butyrolactone; Biological Factors; Butadienes; Ethers, Cyclic; Furans

2000
Chemical studies on the Philippine crude drug calumbibit (seeds of Caesalpinia bonduc): the isolation of new cassane diterpenes fused with alpha,beta-butenolide.
    Chemical & pharmaceutical bulletin, 2000, Volume: 48, Issue:9

    Topics: 4-Butyrolactone; Chloroform; Diterpenes; Furans; Magnetic Resonance Spectroscopy; Philippines; Plants, Medicinal; Solvents; Spectrometry, Mass, Fast Atom Bombardment; Spectrophotometry, Ultraviolet

2000
New butenolides from two marine streptomycetes.
    Journal of natural products, 2000, Volume: 63, Issue:11

    Topics: 4-Butyrolactone; Anti-Bacterial Agents; Bacteria; Circular Dichroism; Fermentation; Furans; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Spores, Fungal; Streptomycetaceae

2000
Synthesis and biological evaluation of purine-containing butenolides.
    Journal of medicinal chemistry, 2001, May-24, Volume: 44, Issue:11

    Topics: 4-Butyrolactone; Adenosylhomocysteinase; Animals; Antineoplastic Agents; Antiviral Agents; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Furans; Herpesvirus 3, Human; Humans; Hydrolases; Kinetics; Magnetic Resonance Spectroscopy; Mice; Purines; Stereoisomerism; Structure-Activity Relationship; Thymidine Kinase; Tumor Cells, Cultured

2001
A novel three-component butenolide synthesis.
    Organic letters, 2001, Sep-06, Volume: 3, Issue:18

    Topics: 4-Butyrolactone; Cyanides; Furans; Glyoxal; Immunosuppressive Agents

2001
Enantioselective synthesis of ancepsenolide and its analogs.
    Bioscience, biotechnology, and biochemistry, 2001, Volume: 65, Issue:8

    Topics: 4-Butyrolactone; Furans; Indicators and Reagents; Magnetic Resonance Spectroscopy; Stereoisomerism

2001
2-buten-4-olide, an endogenous feeding suppressant, improves spatial performance through brain acidic fibroblast growth factor in mice.
    Brain research bulletin, 2001, Volume: 56, Issue:6

    Topics: 4-Butyrolactone; Animals; Antibodies; Appetite Depressants; Blood Glucose; Drug Interactions; Fibroblast Growth Factor 1; Furans; Glucocorticoids; Hippocampus; Male; Maze Learning; Memory; Mice; Neurons; Norepinephrine; Reaction Time; Space Perception

2001
Reactions of purines-containing butenolides with L-cysteine or N-acetyl-L-cysteine as model biological nucleophiles: a potent mechanism-based inhibitor of ribonucleotide reductase caused apoptosis in breast carcinoma MCF7 cells.
    European journal of medicinal chemistry, 2002, Volume: 37, Issue:3

    Topics: 4-Butyrolactone; Acetylcysteine; Animals; Antineoplastic Agents; Apoptosis; Cell Division; Cell Line; Cysteine; Cytarabine; Dose-Response Relationship, Drug; Escherichia coli; Fibroblasts; Furans; Humans; Mice; Molecular Structure; Purines; Ribonucleotide Reductases; Sulfhydryl Compounds; Tumor Cells, Cultured

2002
The total synthesis of the annonaceous acetogenin, muricatetrocin C.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2002, Apr-02, Volume: 8, Issue:7

    Topics: 4-Butyrolactone; Antineoplastic Agents; Furans; Molecular Conformation; Molecular Structure; Plants, Medicinal; Stereoisomerism

2002
De novo synthesis of 4'-ethoxy nucleoside analogues.
    The Journal of organic chemistry, 2002, Nov-01, Volume: 67, Issue:22

    Topics: 4-Butyrolactone; Furans; Hydroxylation; Molecular Structure; Nucleosides; Stereoisomerism

2002
The first enantioselective organocatalytic Mukaiyama-Michael reaction: a direct method for the synthesis of enantioenriched gamma-butenolide architecture.
    Journal of the American Chemical Society, 2003, Feb-05, Volume: 125, Issue:5

    Topics: 4-Butyrolactone; Aldehydes; Catalysis; Furans; Imidazoles; Models, Molecular; Stereoisomerism

2003
Cross-linking of 2-deoxyribonolactone and its beta-elimination product by base excision repair enzymes.
    Biochemistry, 2003, Mar-04, Volume: 42, Issue:8

    Topics: 4-Butyrolactone; Binding Sites; Carbon-Oxygen Lyases; Cross-Linking Reagents; Deoxyribonuclease (Pyrimidine Dimer); DNA Damage; DNA Repair; DNA-(Apurinic or Apyrimidinic Site) Lyase; DNA-Formamidopyrimidine Glycosylase; Endodeoxyribonucleases; Enzyme Inhibitors; Escherichia coli Proteins; Furans; Humans; Hydrolysis; N-Glycosyl Hydrolases; Nucleic Acid Heteroduplexes; Sugar Acids

2003
Two novel ravenelones from the edible mushroom Pulveroboletus ravenelii.
    Chemical & pharmaceutical bulletin, 2003, Volume: 51, Issue:3

    Topics: 4-Butyrolactone; Agaricales; Furans; Plant Extracts; Plant Structures

2003
Palladium catalyzed kinetic and dynamic kinetic asymmetric transformations of gamma-acyloxybutenolides. Enantioselective total synthesis of (+)-Aflatoxin B1 and B2a.
    Journal of the American Chemical Society, 2003, Mar-12, Volume: 125, Issue:10

    Topics: 4-Butyrolactone; Aflatoxin B1; Aflatoxins; Catalysis; Furans; Kinetics; Palladium; Phenols

2003
C2-Symmetric enantiopure ethanotethered bis(alpha,beta-butenolides) as templates for asymmetric synthesis. Application to the synthesis of (+)-grandisol.
    The Journal of organic chemistry, 2003, Mar-21, Volume: 68, Issue:6

    Topics: 4-Butyrolactone; Catalysis; Combinatorial Chemistry Techniques; Furans; Indicators and Reagents; Mannitol; Models, Theoretical; Molecular Conformation; Molecular Structure; Stereoisomerism; Terpenes

2003
NMR determination of absolute configuration of butenolides of annonaceous type.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2002, Dec-16, Volume: 8, Issue:24

    Topics: 4-Butyrolactone; Annonaceae; Furans; Indicators and Reagents; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Solvents

2002
Novel autoxidation and Michael addition of a butenolide-containing sugar leading to a C-branched-chain glucopyranosidulose, and X-ray structure of intermediates.
    Carbohydrate research, 2003, Aug-12, Volume: 338, Issue:17

    Topics: 4-Butyrolactone; Carbohydrate Conformation; Crystallography, X-Ray; Furans; Glucose; Glycosides; Hydrogen Bonding; Ketoses; Malonates; Molecular Structure; Oxidation-Reduction; Stereoisomerism

2003
Design, synthesis, and anticancer activity of phosphonic acid diphosphate derivative of adenine-containing butenolide and its water-soluble derivatives of paclitaxel with high antitumor activity.
    Bioorganic & medicinal chemistry, 2003, Oct-01, Volume: 11, Issue:20

    Topics: 4-Butyrolactone; Adenine; Animals; Antineoplastic Agents; Cell Division; Cell Line, Tumor; Cell Nucleus; Diphosphates; Drug Design; Drug Screening Assays, Antitumor; Furans; Humans; Microtubules; Organophosphonates; Paclitaxel; Prodrugs; Ribonucleoside Diphosphate Reductase; Solubility; Structure-Activity Relationship

2003
[Alpha, beta-substituted delta alpha, beta-butenolides as agents facilitating the dissolution of aminopyrine].
    Arzneimittel-Forschung, 1956, Volume: 6, Issue:4

    Topics: 4-Butyrolactone; Aminopyrine; Furans; Solubility

1956
[Pharmacological studies on the effect of aminopyrine-butenolide-dihydroxypropyltheophylline solutions].
    Pharmazeutische Zentralhalle fur Deutschland, 1960, Volume: 99

    Topics: 4-Butyrolactone; Aminopyrine; Dyphylline; Furans; Research; Solutions; Theophylline

1960
[Inhibition of cortisone inactivation in rat liver homogenate by butenolide and butenolide-dipyrine combinations].
    Acta biologica et medica Germanica, 1960, Volume: 4

    Topics: 4-Butyrolactone; Aminopyrine; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Cortisone; Liver; Physostigmine

1960
BIOSYNTHESIS OF PLANT STEROIDS. I. THE ORIGIN OF THE BUTENOLIDE RING OF DIGITOXIGENIN.
    Journal of the American Chemical Society, 1965, Aug-05, Volume: 87

    Topics: 4-Butyrolactone; Carbon Isotopes; Digitalis; Digitoxigenin; Digitoxin; Metabolism; Mevalonic Acid; Phytosterols; Plant Extracts; Research

1965
Hydroperoxide and endoperoxide lactones from photooxygenation of 3-alkylidenedihydrofuran-2,4-diones.
    The Journal of organic chemistry, 2003, Dec-12, Volume: 68, Issue:25

    Topics: 4-Butyrolactone; Alkenes; Antimalarials; Furans; Hydrogen Peroxide; Lactones; Models, Chemical; Oxidation-Reduction; Peroxides; Photochemistry

2003
Synthesis of the cyclobutanone core of solanoeclepin A intramolecular allene butenolide photocycloaddition.
    Organic & biomolecular chemistry, 2003, Dec-21, Volume: 1, Issue:24

    Topics: 4-Butyrolactone; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Crystallography, X-Ray; Cyclization; Cyclobutanes; Furans; Hexanes; Ketones; Models, Chemical; Molecular Structure; Photochemistry; Stereoisomerism

2003
Lambertellols A and B, novel 3,4-dihydronaphthalen-1(2H)-ones with spiro-butenolide produced by Lambertella sp.1346.
    Organic letters, 2004, Jan-22, Volume: 6, Issue:2

    Topics: 4-Butyrolactone; Ascomycota; Molecular Structure; Naphthalenes; Spiro Compounds

2004
Butenolides from a cultured microfungus, Acremonium sp.
    Natural product research, 2004, Volume: 18, Issue:2

    Topics: 4-Butyrolactone; Acremonium; Furans; Immunosuppressive Agents; Lactones; Spectrum Analysis

2004
Further insights on the structural aspects of PLA(2) inhibition by gamma-hydroxybutenolide-containing natural products: a comparative study on petrosaspongiolides M-R.
    Bioorganic & medicinal chemistry, 2004, Mar-15, Volume: 12, Issue:6

    Topics: 4-Butyrolactone; Animals; Bee Venoms; Binding Sites; Biological Products; Chromatography, High Pressure Liquid; Computational Biology; Enzyme Inhibitors; Furans; Immunosuppressive Agents; Mass Spectrometry; Models, Molecular; Molecular Structure; Oleanolic Acid; Phospholipases A

2004
Development of novel chiral urea catalysts for the hetero-Michael reaction.
    Chemical & pharmaceutical bulletin, 2004, Volume: 52, Issue:4

    Topics: 4-Butyrolactone; Catalysis; Furans; Half-Life; Indicators and Reagents; Kinetics; Magnetic Resonance Spectroscopy; Pyrrolidines; Spectrophotometry, Infrared; Stereoisomerism; Urea

2004
Suzuki cross-coupling reactions of gamma-alkylidenebutenolides: application to the synthesis of vulpinic acid.
    The Journal of organic chemistry, 2004, May-28, Volume: 69, Issue:11

    Topics: 4-Butyrolactone; Boronic Acids; Furans; Molecular Structure; Palladium; Phenylacetates

2004
Cytotoxicity of 3,4-dihalogenated 2(5H)-furanones.
    The Journal of pharmacy and pharmacology, 2004, Volume: 56, Issue:9

    Topics: 4-Butyrolactone; Animals; Antineoplastic Agents; Cell Line, Tumor; Furans; Mice

2004
Synthesis and determination of the absolute configuration of fugomycin and desoxyfugomycin: CD spectroscopy and fungicidal activity of butenolides.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2004, Sep-20, Volume: 10, Issue:18

    Topics: 4-Butyrolactone; Alkenes; Antifungal Agents; Botrytis; Circular Dichroism; Lactones; Molecular Structure

2004
The potato eelworm hatching factor; attempts to prepare artificial hatching agents; some active arylidene-delta beta :gamma-butenolides and related compounds.
    The Biochemical journal, 1949, Volume: 45, Issue:5

    Topics: 4-Butyrolactone; Animals; Gamma Rays; Helminths; Solanum tuberosum

1949
Stereochemical features of Lewis acid-promoted glycosidations involving 4'-spiroannulated DNA building blocks.
    The Journal of organic chemistry, 2004, Oct-29, Volume: 69, Issue:22

    Topics: 4-Butyrolactone; Catalysis; Crystallography, X-Ray; DNA; Glycosides; Models, Molecular; Molecular Conformation; Molecular Mimicry; Molecular Structure; Spiro Compounds; Stereoisomerism; Tin Compounds

2004
Regio- and stereoselective construction of gamma-butenolides through phosphine-catalyzed substitution of Morita-Baylis-Hillman acetates: an organocatalytic allylic alkylation.
    Angewandte Chemie (International ed. in English), 2004, Dec-10, Volume: 43, Issue:48

    Topics: 4-Butyrolactone; Acetates; Alkylation; Allyl Compounds; Catalysis; Furans; Molecular Structure; Phosphines; Stereoisomerism

2004
Dimerization of butenolide structures. A biomimetic approach to the dimeric sesquiterpene lactones (+/-)-biatractylolide and (+/-)-biepiasterolide.
    The Journal of organic chemistry, 2004, Dec-24, Volume: 69, Issue:26

    Topics: 4-Butyrolactone; Dimerization; Furans; Models, Molecular; Molecular Mimicry; Molecular Structure; Sesquiterpenes; Spectrum Analysis; X-Ray Diffraction

2004
I(-)-catalyzed methyl-oxygen bond cleavage in 2-methoxyfurans. An efficient synthesis of butenolides.
    The Journal of organic chemistry, 2005, Feb-04, Volume: 70, Issue:3

    Topics: 4-Butyrolactone; Appetite Depressants; Crystallography, X-Ray; Furans; Immunosuppressive Agents; Iodides

2005
Novel strategy for the synthesis of the butenolide moiety of peridinin.
    Angewandte Chemie (International ed. in English), 2005, Feb-25, Volume: 44, Issue:10

    Topics: 4-Butyrolactone; Carotenoids

2005
The Stille reaction in the synthesis of carotenoid butenolides: synthesis of 6'-epi-peridinin.
    Organic letters, 2005, Feb-17, Volume: 7, Issue:4

    Topics: 4-Butyrolactone; Carotenoids; Models, Molecular; Molecular Conformation; Palladium

2005
Biomimetic total synthesis of (+)-himbacine.
    Organic letters, 2005, Feb-17, Volume: 7, Issue:4

    Topics: 4-Butyrolactone; Aldehydes; Alkaloids; Alkenes; Furans; Models, Molecular; Naphthalenes; Piperidines; Stereoisomerism; Trifluoroacetic Acid

2005
Enantioselective syntheses and configuration assignments of gamma-chiral butenolides from Plagiomnium undulatum: butenolide synthesis from tetronic acids.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2005, Mar-18, Volume: 11, Issue:7

    Topics: 4-Butyrolactone; Bryopsida; Furans; Lactones; Molecular Conformation; Stereoisomerism; Time Factors

2005
Sesquiterpenes and butenolides, natural anti-HIV constituents from Litsea verticillata.
    Planta medica, 2005, Volume: 71, Issue:5

    Topics: 4-Butyrolactone; Anti-HIV Agents; HIV-1; Humans; Inhibitory Concentration 50; Litsea; Phytotherapy; Plant Extracts; Sesquiterpenes

2005
Rh(I)-catalyzed CO gas-free cyclohydrocarbonylation of alkynes with formaldehyde to alpha,beta-butenolides.
    Chemical communications (Cambridge, England), 2005, Jul-14, Issue:26

    Topics: 4-Butyrolactone; Alkynes; Carbon Monoxide; Catalysis; Cyclization; Formaldehyde; Molecular Structure; Rhodium; Stereoisomerism

2005
(E)-5-(Tributylstannylmethylidene)-5H-furan-2-ones: versatile synthons for the stereospecific elaboration of gamma-alkylidenebutenolide skeletons.
    Organic letters, 1999, Sep-09, Volume: 1, Issue:5

    Topics: 4-Butyrolactone; Catalysis; Chromatography, Ion Exchange; Cyclization; Furans; Indicators and Reagents; Magnetic Resonance Spectroscopy; Palladium; Solvents; Stereoisomerism; Thermodynamics; Trialkyltin Compounds

1999
Biological activities of retinoidal gamma-hydroxybutenolides in cancer cell apoptosis and differentiation.
    Bioorganic & medicinal chemistry, 2005, Nov-01, Volume: 13, Issue:21

    Topics: 4-Butyrolactone; Apoptosis; Cell Differentiation; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; Hydrogen; Molecular Structure; Neoplasms; Transcription, Genetic; Tretinoin

2005
Uncatalyzed Mukaiyama-Michael reaction: rapid access to simple and complex enantiopure gamma-butenolides.
    Angewandte Chemie (International ed. in English), 2005, Oct-14, Volume: 44, Issue:40

    Topics: 4-Butyrolactone; Hydrocarbons; Methane; Molecular Structure; Stereoisomerism

2005
Heteroatom-guided torquoselective olefination of alpha-oxy and alpha-amino ketones via ynolates.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2005, Dec-23, Volume: 12, Issue:2

    Topics: 4-Butyrolactone; Alkenes; Amines; Chemistry, Organic; Ketones

2005
Progress in the synthesis of the lituarines: stereocontrol in sequential C-C bond formation on a spirobutenolide template.
    Organic letters, 2005, Oct-27, Volume: 7, Issue:22

    Topics: 4-Butyrolactone; Carbon; Epoxy Compounds; Macrocyclic Compounds; Molecular Structure; Spiro Compounds; Stereoisomerism

2005
Divergence en route to nonclassical annonaceous acetogenins. Synthesis of pyranicin and pyragonicin.
    The Journal of organic chemistry, 2006, Mar-03, Volume: 71, Issue:5

    Topics: 4-Butyrolactone; Acetogenins; Catalysis; Cyclization; Fatty Alcohols; Furans; Lactones; Platinum; Pyrans; Stereoisomerism

2006
New peanut (Arachis hypogaea) phytoalexin with prenylated benzenoid and but-2-enolide moieties.
    Journal of agricultural and food chemistry, 2006, Mar-22, Volume: 54, Issue:6

    Topics: 4-Butyrolactone; Arachis; Benzene; Phytoalexins; Plant Extracts; Protein Prenylation; Seeds; Sesquiterpenes; Stilbenes; Terpenes

2006
The short chain sugar acid, 2-buten-4-olide, activates oxytocin-secreting neurons but not arginine vasopressin-secreting neurons in the hypothalamus of rats.
    Brain research, 2006, May-01, Volume: 1086, Issue:1

    Topics: 4-Butyrolactone; Analysis of Variance; Animals; Appetite Depressants; Arginine Vasopressin; Cell Count; Hypothalamus; Immunohistochemistry; Male; Neurons; Oxytocin; Radioimmunoassay; Rats; Rats, Inbred Lew

2006
Solution-phase parallel synthesis with oligoethylene glycol sorting tags. Preparation of all four stereoisomers of the hydroxybutenolide fragment of murisolin and related acetogenins.
    The Journal of organic chemistry, 2006, Apr-28, Volume: 71, Issue:9

    Topics: 4-Butyrolactone; Acetogenins; Ethylene Glycols; Fatty Alcohols; Furans; Lactones; Magnetic Resonance Spectroscopy; Stereoisomerism

2006
Diastereoselective, vinylogous mukaiyama aldol additions of silyloxy furans to cyclic ketones: annulation of butenolides and gamma-lactones.
    Organic letters, 2006, Jul-06, Volume: 8, Issue:14

    Topics: 4-Butyrolactone; Catalysis; Furans; Ketones; Lactones; Molecular Structure; Silanes; Stereoisomerism

2006
Major secondary metabolites produced by two commercial Trichoderma strains active against different phytopathogens.
    Letters in applied microbiology, 2006, Volume: 43, Issue:2

    Topics: 4-Butyrolactone; Anthraquinones; Antibiosis; Ascomycota; Benzopyrans; Fungi; Fungicides, Industrial; Industrial Microbiology; Pigments, Biological; Pythium; Rhizoctonia; Trichoderma

2006
The Stille reaction in the synthesis of the C37-norcarotenoid butenolide pyrrhoxanthin. Scope and limitations.
    The Journal of organic chemistry, 2006, Aug-04, Volume: 71, Issue:16

    Topics: 4-Butyrolactone; Carbon; Carotenoids; Magnetic Resonance Spectroscopy; Molecular Structure

2006
[Toxic effect of butenolide on chondrocyte differentiation and the protective effect of selenium].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2006, Volume: 28, Issue:3

    Topics: 4-Butyrolactone; Cell Differentiation; Cells, Cultured; Chondrocytes; Humans; Protective Agents; Selenium; T-2 Toxin

2006
Regioselective entry to bromo-gamma-hydroxybutenolides: useful building blocks for assemblying natural product-like libraries.
    Organic letters, 2006, Oct-12, Volume: 8, Issue:21

    Topics: 4-Butyrolactone; Biological Products; Combinatorial Chemistry Techniques; Hydrocarbons, Brominated; Molecular Structure; Stereoisomerism

2006
A highly efficient and practical method for catalytic asymmetric vinylogous Mannich (AVM) reactions.
    Angewandte Chemie (International ed. in English), 2006, Nov-06, Volume: 45, Issue:43

    Topics: 4-Butyrolactone; Catalysis; Imines; Molecular Structure; Organosilicon Compounds; Silver; Stereoisomerism

2006
Divergent synthetic strategy leading to structurally diverse pyrrolidines and piperidines from common gamma-aminoalkyl butenolide and aldehyde precursors.
    The Journal of organic chemistry, 2006, Nov-10, Volume: 71, Issue:23

    Topics: 4-Butyrolactone; Aldehydes; Cyclization; Free Radicals; Molecular Structure; Piperidines; Pyrrolidines; Stereoisomerism

2006
A novel gene cluster in Fusarium graminearum contains a gene that contributes to butenolide synthesis.
    Fungal genetics and biology : FG & B, 2007, Volume: 44, Issue:4

    Topics: 4-Butyrolactone; Fusarium; Gene Expression Regulation; Genes, Fungal; Multigene Family

2007
Effects of the short chain sugar acid 2-buten-4-olide on the hypothalamo-pituitary-adrenal axis in normal and adjuvant-induced arthritic rats.
    Journal of neuroendocrinology, 2007, Volume: 19, Issue:1

    Topics: 4-Butyrolactone; Adjuvants, Immunologic; Animals; Appetite Depressants; Arginine Vasopressin; Arthritis, Experimental; Corticosterone; Corticotropin-Releasing Hormone; Hypothalamo-Hypophyseal System; Injections, Intraperitoneal; Male; Pituitary-Adrenal System; Proto-Oncogene Proteins c-fos; Rats; Rats, Inbred Lew

2007
Novel synthons from mucochloric acid: the first use of alpha,beta-dichloro-gamma-butenolides and gamma-butyrolactams for direct vinylogous aldol addition.
    The Journal of organic chemistry, 2007, Apr-27, Volume: 72, Issue:9

    Topics: 4-Butyrolactone; Aldehydes; Chemistry, Organic; Furans

2007
The oxidative damage of butenolide to isolated erythrocyte membranes.
    Toxicology in vitro : an international journal published in association with BIBRA, 2007, Volume: 21, Issue:5

    Topics: 4-Butyrolactone; Adenosine Triphosphatases; Animals; Electron Spin Resonance Spectroscopy; Erythrocyte Membrane; Fatty Acids, Unsaturated; Lipid Peroxidation; Male; Membrane Proteins; Mycotoxins; Oxidative Stress; Protein Conformation; Rats; Rats, Wistar; Spin Labels; Sulfhydryl Compounds; Thiobarbituric Acid Reactive Substances

2007
Design and total synthesis of unnatural analogues of the sub-nanomolar SERCA inhibitor thapsigargin.
    Organic & biomolecular chemistry, 2007, May-07, Volume: 5, Issue:9

    Topics: 4-Butyrolactone; Drug Design; Enzyme Inhibitors; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Thapsigargin

2007
[Butenolide induces apoptosis of cultured chondrocytes: study of its mechanism].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2007, Volume: 27, Issue:4

    Topics: 4-Butyrolactone; Apoptosis; bcl-2-Associated X Protein; Cells, Cultured; Chondrocytes; Humans; In Situ Nick-End Labeling; Proto-Oncogene Proteins c-bcl-2; Selenium

2007
Synthesis of novel antitumoural analogues of dysidiolide from ent-halimic acid.
    Bioorganic & medicinal chemistry, 2007, Sep-01, Volume: 15, Issue:17

    Topics: 4-Butyrolactone; Aldehydes; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Humans; Hydroxylation; Ketones; Models, Molecular; Molecular Structure; Sesterterpenes; Stereoisomerism; Structure-Activity Relationship; Terpenes

2007
Toxic effects of Fusarium mycotoxin butenolide on rat myocardium and primary culture of cardiac myocytes.
    Toxicon : official journal of the International Society on Toxinology, 2007, Sep-01, Volume: 50, Issue:3

    Topics: 4-Butyrolactone; Animals; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Fusarium; Heart; Lipid Peroxidation; Molecular Structure; Mycotoxins; Myocytes, Cardiac; Rats; Time Factors

2007
Fluoride-assisted regioselective conversion of functionalized furans to alpha-substituted gamma-hydroxybutenolides using singlet oxygen.
    The Journal of organic chemistry, 2007, Aug-03, Volume: 72, Issue:16

    Topics: 4-Butyrolactone; Catalysis; Chemistry, Organic; Fluorides; Furans; Models, Chemical; Oxygen; Quaternary Ammonium Compounds; Singlet Oxygen; Stereoisomerism

2007
Easy and stereoselective approach to alpha,beta-unsaturated gamma-lactones fused to pyranoses from furanose scaffolds.
    Organic letters, 2007, Aug-16, Volume: 9, Issue:17

    Topics: 4-Butyrolactone; Appetite Depressants; Furans; Hexoses; Immunosuppressive Agents; Lactones; Pyrans; Stereoisomerism

2007
Synthesis and optical resolution of an allenoic acid by diastereomeric salt formation induced by chiral alkaloids.
    Chirality, 2008, Volume: 20, Issue:1

    Topics: 4-Butyrolactone; Acids; Alkaloids; Cinchona Alkaloids; Crystallography, X-Ray; Optics and Photonics; Phosphoranes; Salts; Stereoisomerism

2008
Discovery of the apoptosis-inducing activity and high accumulation of the butenolides, menisdaurilide and aquilegiolide in Dicentra spectabilis.
    Planta medica, 2007, Volume: 73, Issue:15

    Topics: 4-Butyrolactone; Antineoplastic Agents, Phytogenic; Apoptosis; Benzofurans; Cell Line, Tumor; Fumariaceae; HT29 Cells; Humans; Jurkat Cells; Phytotherapy; Plant Extracts; Plant Leaves; Plant Stems

2007
A simple chemical method for synthesizing malonyl hemiesters of 21-hydroxypregnanes, potential intermediates in cardenolide biosynthesis.
    Steroids, 2008, Volume: 73, Issue:4

    Topics: 4-Butyrolactone; Cardenolides; Digitoxigenin; Esters; Gas Chromatography-Mass Spectrometry; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Structure; Pregnanes; Pregnenolone

2008
Direct catalytic asymmetric Mannich-type reactions of gamma-butenolides: effectiveness of Brønsted acid in chiral metal catalysis.
    Organic letters, 2008, Jun-05, Volume: 10, Issue:11

    Topics: 4-Butyrolactone; Acids; Catalysis; Imines; Mannich Bases; Metals; Stereoisomerism; Substrate Specificity

2008
Efficient conversion of carbohydrates into 1-C-alditols: application to the synthesis of chiral gamma-substituted butenolides and bicyclic alkaloid analogues.
    The Journal of organic chemistry, 2008, Jul-18, Volume: 73, Issue:14

    Topics: 4-Butyrolactone; Acetals; Alkaloids; Alkylation; Bridged Bicyclo Compounds, Heterocyclic; Carbohydrates; Esterification; Hydroxylation; Ketones; Magnetic Resonance Spectroscopy; Molecular Structure; Stereoisomerism

2008
A smoke-derived butenolide alleviates HgCl2 and ZnCl2 inhibition of water uptake during germination and subsequent growth of tomato--possible involvement of aquaporins.
    Journal of plant physiology, 2008, Sep-08, Volume: 165, Issue:13

    Topics: 4-Butyrolactone; Aquaporins; Chlorides; Dose-Response Relationship, Drug; Germination; Mercuric Chloride; Plant Roots; Plant Shoots; Smoke; Solanum lycopersicum; Water; Zinc Compounds

2008
Lipid peroxidation and antioxidant defense impairment in the hearts of chick embryos induced by in ovo exposure to Fusarium mycotoxin butenolide.
    Toxicon : official journal of the International Society on Toxinology, 2008, Dec-01, Volume: 52, Issue:7

    Topics: 4-Butyrolactone; Animals; Antioxidants; Ascorbic Acid; Chick Embryo; Embryo, Nonmammalian; Fusarium; Glutathione Peroxidase; Heart; Lipid Peroxidation; Mycotoxins; Oxidative Stress; Sodium Selenite; Sulfhydryl Compounds; Toxicity Tests

2008
General, regiodefined access to alpha-substituted butenolides through metal-halogen exchange of 3-bromo-2-silyloxyfurans. Efficient synthesis of an anti-inflammatory gorgonian lipid.
    The Journal of organic chemistry, 2008, Oct-17, Volume: 73, Issue:20

    Topics: 4-Butyrolactone; Anti-Inflammatory Agents; Bromine; Furans; Lactones; Lipids; Lithium

2008
A concise and modular synthesis of pyranicin.
    Organic letters, 2008, Nov-06, Volume: 10, Issue:21

    Topics: 4-Butyrolactone; Furans; Lactones; Molecular Structure

2008
Antiproliferative compounds of Artabotrys madagascariensis from the Madagascar rainforest.
    Natural product research, 2008, Volume: 22, Issue:13

    Topics: 4-Butyrolactone; Annonaceae; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Humans; Madagascar; Magnetic Resonance Spectroscopy; Molecular Structure; Plant Extracts; Triterpenes

2008
The constitution of kappa-santonin; a study of the butenolide system.
    Journal of the Chemical Society, 1947, Volume: 25

    Topics: 4-Butyrolactone; Humans; Santonin

1947
Bioactivity and chemistry of the genus Hortonia.
    Natural product research, 2008, Volume: 22, Issue:16

    Topics: 4-Butyrolactone; Animals; Antifungal Agents; Cladosporium; Culicidae; Larva; Monimiaceae; Mosquito Control; Plant Bark; Plant Leaves; Plant Roots; Sri Lanka; Structure-Activity Relationship

2008
Stereoselective rhodium-catalyzed conjugate addition of boronic acids to unprotected delta-hydroxy-gamma-butenolides. Synthesis of (-)-7-oxamuricatacin and beta-substituted derivatives.
    The Journal of organic chemistry, 2009, Jan-02, Volume: 74, Issue:1

    Topics: 4-Butyrolactone; Boronic Acids; Catalysis; Furans; Molecular Conformation; Rhodium; Stereoisomerism

2009
Butenolide induced cytotoxicity by disturbing the prooxidant-antioxidant balance, and antioxidants partly quench in human chondrocytes.
    Toxicology in vitro : an international journal published in association with BIBRA, 2009, Volume: 23, Issue:1

    Topics: 4-Butyrolactone; Ascorbic Acid; Cartilage, Articular; Cell Survival; Cells, Cultured; Chondrocytes; Dose-Response Relationship, Drug; Drug Antagonism; Free Radical Scavengers; Glutathione; Humans; Immunosuppressive Agents; Lipid Peroxidation; Oxidative Stress; Oxidoreductases; Selenium; Tissue Engineering; Vitamin E

2009
Basal expression of metallothionein suppresses butenolide-induced oxidative stress in liver homogenates in vitro.
    Toxicon : official journal of the International Society on Toxinology, 2009, Volume: 53, Issue:2

    Topics: 4-Butyrolactone; Animals; Dose-Response Relationship, Drug; Gene Expression Regulation; Glutathione; Glutathione Peroxidase; Lipid Peroxidation; Liver; Metallothionein; Mice; Mice, Knockout; Nitric Oxide; Oxidative Stress; Superoxide Dismutase

2009
Repeated administration of a Fusarium mycotoxin butenolide to rats induces hepatic lipid peroxidation and antioxidant defense impairment.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2009, Volume: 47, Issue:3

    Topics: 4-Butyrolactone; Animals; Antioxidants; Lipid Peroxidation; Liver; Male; Rats; Rats, Wistar

2009
Total synthesis of ouabagenin and ouabain.
    Chemistry, an Asian journal, 2009, May-04, Volume: 4, Issue:5

    Topics: 4-Butyrolactone; Crystallography, X-Ray; Cyclization; Ouabain; Oxidation-Reduction; Stereoisomerism

2009
Synthesis of new chiral 2,5-disubstituted 1,3,4-thiadiazoles possessing gamma-butenolide moiety and preliminary evaluation of in vitro anticancer activity.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:8

    Topics: 4-Butyrolactone; Antineoplastic Agents; Cell Proliferation; Drug Design; HeLa Cells; Humans; Stereoisomerism; Thiadiazoles

2009
Asymmetric total synthesis of pyranicin.
    Organic letters, 2009, Jun-18, Volume: 11, Issue:12

    Topics: 4-Butyrolactone; Alkylation; Cyclization; Furans; Lactones; Molecular Structure; Stereoisomerism

2009
Synthesis of 5,5-disubstituted butenolides based on a Pd-catalyzed gamma-arylation strategy.
    Organic letters, 2009, Jun-18, Volume: 11, Issue:12

    Topics: 4-Butyrolactone; Catalysis; Molecular Structure; Palladium; Tetrahydroisoquinolines

2009
Synthesis of functionalized alpha-pyrone and butenolide derivatives by rhodium-catalyzed oxidative coupling of substituted acrylic acids with alkynes and alkenes.
    The Journal of organic chemistry, 2009, Aug-21, Volume: 74, Issue:16

    Topics: 4-Butyrolactone; Acrylates; Alkenes; Alkynes; Catalysis; Oxidation-Reduction; Pyrones; Rhodium

2009
In ovo exposure of a Fusarium mycotoxin butenolide induces hepatic and renal oxidative damage in chick embryos, and antioxidants provide protections.
    Toxicology in vitro : an international journal published in association with BIBRA, 2009, Volume: 23, Issue:7

    Topics: 4-Butyrolactone; Animals; Antioxidants; Ascorbic Acid; Chick Embryo; Fusarium; Glutathione Peroxidase; Injections; Kidney; Lipid Peroxidation; Liver; Models, Animal; Mycotoxins; Ovum; Oxidative Stress; Protective Agents; Sodium Selenite; Superoxide Dismutase

2009
Calixpyrrole derivatives: "multi hydrogen bond" catalysts for gamma-butenolide synthesis.
    Molecules (Basel, Switzerland), 2009, Jul-15, Volume: 14, Issue:7

    Topics: 4-Butyrolactone; Aldehydes; Calixarenes; Catalysis; Furans; Hydrogen Bonding; Porphyrins

2009
Concise syntheses of the natural products (+)-sylvaticin and (+)-cis-sylvaticin.
    Journal of the American Chemical Society, 2009, Sep-09, Volume: 131, Issue:35

    Topics: 4-Butyrolactone; Alkenes; Biological Products; Cyclization; Furans; Hydroxylation; Oxidation-Reduction; Stereoisomerism

2009
Enzymatic kinetic resolution of primary allenic alcohols. Application to the total synthesis and stereochemical assignment of striatisporolide A.
    Organic & biomolecular chemistry, 2009, Sep-07, Volume: 7, Issue:17

    Topics: 4-Butyrolactone; Alcohols; Alkadienes; Animals; Esterification; Immunosuppressive Agents; Kinetics; Lipase; Penicillium; Stereoisomerism; Swine

2009
Cycloaddition and one-carbon homologation studies in the synthesis of advanced iridoid precursors.
    Organic & biomolecular chemistry, 2009, Sep-07, Volume: 7, Issue:17

    Topics: 4-Butyrolactone; Carbon; Crystallography, X-Ray; Glucosides; Iridoid Glucosides; Iridoids; Molecular Conformation; Organic Chemistry Phenomena

2009
Three adducts of butenolide and apigenin glycoside from the leaves of Machilus japonica.
    Journal of natural products, 2009, Volume: 72, Issue:7

    Topics: 4-Butyrolactone; Apigenin; Bacillus; Glycoside Hydrolase Inhibitors; Glycosides; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Leaves; Plants, Medicinal; Taiwan

2009
Oxidative cyclization-dimerization reaction of 2,3-allenoic acids and 1,2-allenyl ketones: an efficient synthesis of 4-(3'-furanyl)butenolide derivatives.
    Angewandte Chemie (International ed. in English), 2002, May-17, Volume: 41, Issue:10

    Topics: 4-Butyrolactone; Alkadienes; Chemistry, Organic; Cyclization; Dimerization; Halogens; Hydrochloric Acid; Ketones; Models, Chemical; Solvents; Stereoisomerism

2002
Effects of Fusarium mycotoxin butenolide on myocardial mitochondria in vitro.
    Toxicology mechanisms and methods, 2009, Volume: 19, Issue:2

    Topics: 4-Butyrolactone; Animals; Cells, Cultured; Fusarium; Humans; Immunosuppressive Agents; Lipid Peroxidation; Membrane Potential, Mitochondrial; Mitochondria, Heart; Molecular Structure; Mycotoxicosis; Mycotoxins; Myocytes, Cardiac; Rats; Rats, Wistar

2009
Identification of alkyl substituted 2H-furo[2,3-c]pyran-2-ones as germination stimulants present in smoke.
    Journal of agricultural and food chemistry, 2009, Oct-28, Volume: 57, Issue:20

    Topics: 4-Butyrolactone; Germination; Seeds; Smoke; Solanum

2009
Antimicrobial activities of some synthetic butenolides and their pyrrolone derivatives.
    Journal of enzyme inhibition and medicinal chemistry, 2010, Volume: 25, Issue:1

    Topics: 4-Butyrolactone; Anti-Infective Agents; Magnetic Resonance Spectroscopy; Mass Spectrometry; Microbial Sensitivity Tests; Pyrroles; Spectrophotometry, Infrared

2010
Butenolides from plant-derived smoke: natural plant-growth regulators with antagonistic actions on seed germination.
    Journal of natural products, 2010, Feb-26, Volume: 73, Issue:2

    Topics: 4-Butyrolactone; Fires; Furans; Germination; Molecular Structure; Plant Growth Regulators; Plants; Pyrans; Seeds; Smoke

2010
Direct asymmetric allylic alkylation of butenolides with Morita-Baylis-Hillman carbonates.
    Organic letters, 2010, Feb-19, Volume: 12, Issue:4

    Topics: 4-Butyrolactone; Alkylation; Allyl Compounds; Carbonates; Catalysis; Cinchona Alkaloids; Combinatorial Chemistry Techniques; Molecular Structure; Stereoisomerism

2010
Metallothionein-I/II null cardiomyocytes are sensitive to Fusarium mycotoxin butenolide-induced cytotoxicity and oxidative DNA damage.
    Toxicon : official journal of the International Society on Toxinology, 2010, Jun-15, Volume: 55, Issue:7

    Topics: 4-Butyrolactone; Animals; Cell Survival; Cells, Cultured; Comet Assay; DNA Damage; Fusarium; Indicators and Reagents; Metallothionein; Mice; Mice, Knockout; Mycotoxins; Myocytes, Cardiac; Oxidative Stress; Reactive Oxygen Species

2010
Digoxin derivatives substituted by alkylidene at the butenolide part.
    Steroids, 2010, Volume: 75, Issue:6

    Topics: 4-Butyrolactone; Animals; Biological Assay; Digoxin; Guinea Pigs; Heart; Humans; Magnetic Resonance Spectroscopy; Molecular Structure; Spectrophotometry, Infrared

2010
Efficient direct asymmetric vinylogous Michael addition reactions of gamma-butenolides to chalcones catalyzed by vicinal primary-diamine salts.
    Chemical communications (Cambridge, England), 2010, Mar-28, Volume: 46, Issue:12

    Topics: 4-Butyrolactone; Catalysis; Chalcones; Crystallography, X-Ray; Models, Molecular; Stereoisomerism

2010
Estrogenic and serotonergic butenolides from the leaves of Piper hispidum Swingle (Piperaceae).
    Journal of ethnopharmacology, 2010, May-27, Volume: 129, Issue:2

    Topics: 4-Butyrolactone; Estrogens; Gene Expression; Genes, Reporter; Humans; Inhibitory Concentration 50; Molecular Structure; Phytoestrogens; Piperaceae; Plant Extracts; Plant Leaves; Receptors, Serotonin; Serotonin Receptor Agonists

2010
Bioactive metabolites from cultures of basidiomycete Favolaschia tonkinensis.
    Journal of natural products, 2010, Apr-23, Volume: 73, Issue:4

    Topics: 4-Butyrolactone; Animals; Antifungal Agents; Antimalarials; Basidiomycota; Benzoxepins; Candida albicans; Chlorocebus aethiops; Cytotoxins; Drug Screening Assays, Antitumor; Fatty Acids, Unsaturated; Female; Humans; KB Cells; Methacrylates; Microbial Sensitivity Tests; Molecular Structure; Plasmodium falciparum; Pyrazoles; Pyrimidines; Strobilurins; Thailand; Vero Cells

2010
A butenolide intermediate in methylenomycin furan biosynthesis is implied by incorporation of stereospecifically 13C-labelled glycerols.
    Chemical communications (Cambridge, England), 2010, Jun-21, Volume: 46, Issue:23

    Topics: 4-Butyrolactone; Anti-Bacterial Agents; Carbon Isotopes; Furans; Glycerol; Stereoisomerism; Streptomyces

2010
Anti-parasitic compounds from Streptomyces sp. strains isolated from Mediterranean sponges.
    Marine drugs, 2010, Feb-23, Volume: 8, Issue:2

    Topics: 4-Butyrolactone; Animals; Leishmania major; Magnetic Resonance Spectroscopy; Porifera; Staurosporine; Streptomyces; Trypanocidal Agents; Trypanosoma brucei brucei; Valinomycin

2010
Diastereo- and enantioselective organocatalytic direct conjugate addition of gamma-butenolide to chalcones.
    Chemistry, an Asian journal, 2010, Jun-01, Volume: 5, Issue:6

    Topics: 4-Butyrolactone; Catalysis; Chalcones; Stereoisomerism; Thiourea

2010
Comparative proteome and phosphoproteome analyses during cyprid development of the barnacle Balanus (=Amphibalanus) amphitrite.
    Journal of proteome research, 2010, Jun-04, Volume: 9, Issue:6

    Topics: 4-Butyrolactone; Animals; Blotting, Western; Down-Regulation; Electrophoresis, Gel, Two-Dimensional; Fluorescence; Heat-Shock Proteins; Hydrogen-Ion Concentration; Isoelectric Focusing; Larva; Phosphoproteins; Phosphorylation; Proteome; Proteomics; Stress, Physiological; Thoracica; Up-Regulation

2010
Syntheses of ylidenbutenolide-modified derivatives of peridinin and their stereochemical and spectral characteristics.
    Organic & biomolecular chemistry, 2010, Jun-07, Volume: 8, Issue:11

    Topics: 4-Butyrolactone; Carotenoids; Molecular Structure; Spectrum Analysis; Stereoisomerism

2010
Gold-catalyzed three-component tandem process: an efficient and facile assembly of complex butenolides from alkynes, amines, and glyoxylic acid.
    Journal of the American Chemical Society, 2010, Jun-02, Volume: 132, Issue:21

    Topics: 4-Butyrolactone; Alkynes; Amines; Catalysis; Glyoxylates; Gold

2010
2-Buten-4-Olide (2-B4O) suppresses feeding in neonate and developing rat pups.
    Physiology & behavior, 2010, Sep-01, Volume: 101, Issue:2

    Topics: 4-Butyrolactone; Age Factors; Animals; Animals, Newborn; Appetite Depressants; Body Weight; Dose-Response Relationship, Drug; Drug Administration Routes; Fasting; Feeding Behavior; Hypothalamus; Rats; Statistics, Nonparametric; Time Factors

2010
Asymmetric direct vinylogous aldol reaction of unactivated gamma-butenolide to aldehydes.
    The Journal of organic chemistry, 2010, Aug-06, Volume: 75, Issue:15

    Topics: 4-Butyrolactone; Aldehydes; Chromatography, High Pressure Liquid; Magnetic Resonance Spectroscopy; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Stereoisomerism

2010
Asymmetric vinylogous Michael reaction of alpha,beta-unsaturated ketones with gamma-butenolide under multifunctional catalysis.
    Chemical communications (Cambridge, England), 2010, Aug-28, Volume: 46, Issue:32

    Topics: 4-Butyrolactone; Amines; Catalysis; Crystallography, X-Ray; Ketones; Molecular Conformation; Stereoisomerism

2010
The fire ephemeral Tersonia cyathiflora (Gyrostemonaceae) germinates in response to smoke but not the butenolide 3-methyl-2H-furo[2,3-c]pyran-2-one.
    Annals of botany, 2010, Volume: 106, Issue:2

    Topics: 4-Butyrolactone; Germination; Magnoliopsida; Seeds; Smoke

2010
A new angucycline and a new butenolide isolated from lichen-derived Streptomyces spp.
    The Journal of antibiotics, 2010, Volume: 63, Issue:9

    Topics: 4-Butyrolactone; Anti-Bacterial Agents; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; DNA, Bacterial; DNA, Ribosomal; Humans; Lichens; Magnetic Resonance Spectroscopy; Mass Spectrometry; Micrococcus luteus; Molecular Sequence Data; Molecular Structure; Quinones; RNA, Ribosomal, 16S; Sequence Analysis, DNA; Streptomyces

2010
Butenolide and furandione from an endophytic Aspergillus terreus.
    Chemical & pharmaceutical bulletin, 2010, Volume: 58, Issue:9

    Topics: 4-Butyrolactone; Anti-Bacterial Agents; Aspergillus; Bacteria; Bacterial Infections; Furans; Magnetic Resonance Spectroscopy; Mammea; Mass Spectrometry

2010
Changes in the proteome and phosphoproteome expression in the bryozoan Bugula neritina larvae in response to the antifouling agent butenolide.
    Proteomics, 2010, Volume: 10, Issue:19

    Topics: 4-Butyrolactone; Animals; Bryozoa; Electrophoresis, Gel, Two-Dimensional; Gene Expression Regulation; Larva; Metamorphosis, Biological; Phosphoproteins; Proteome; Proteomics; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2010
Cu(II)-catalyzed acylation by thiol esters under neutral conditions: tandem acylation-wittig reaction leading to a one-pot synthesis of butenolides.
    Organic letters, 2010, Nov-19, Volume: 12, Issue:22

    Topics: 4-Butyrolactone; Acylation; Alcohols; Catalysis; Combinatorial Chemistry Techniques; Copper; Esters; Molecular Structure; Sulfhydryl Compounds

2010
Organocatalytic asymmetric direct vinylogous aldol reactions of γ-crotonolactone with aromatic aldehydes.
    Chemical communications (Cambridge, England), 2011, Jan-21, Volume: 47, Issue:3

    Topics: 4-Butyrolactone; Aldehydes; Catalysis; Furans; Semicarbazides

2011
Three new bis-styryllactones from Goniothalamus cheliensis.
    Fitoterapia, 2011, Volume: 82, Issue:4

    Topics: 4-Butyrolactone; Furans; Goniothalamus; Magnetic Resonance Spectroscopy; Molecular Structure; Plant Bark; Plant Roots; Plants, Medicinal; Pyrones; Spectrometry, Mass, Electrospray Ionization

2011
Eutypoids B-E produced by a Penicillium sp. strain from the North Sea.
    Journal of natural products, 2011, Jan-28, Volume: 74, Issue:1

    Topics: 4-Butyrolactone; Aminophenols; Animals; Anti-Bacterial Agents; Antineoplastic Agents; Bacteria; Candida glabrata; Dipeptides; Drug Screening Assays, Antitumor; Glycogen Synthase Kinases; Hep G2 Cells; HT29 Cells; Humans; Maleimides; Mice; Microbial Sensitivity Tests; Molecular Structure; NIH 3T3 Cells; North Sea; Nuclear Magnetic Resonance, Biomolecular; Penicillium; Peptides, Cyclic; Xanthomonas campestris

2011
Catalytic enantioselective synthesis of naturally occurring butenolides via hetero-allylic alkylation and ring closing metathesis.
    Organic letters, 2011, Mar-04, Volume: 13, Issue:5

    Topics: 4-Butyrolactone; Alkylation; Allyl Compounds; Biological Products; Catalysis; Furans; Molecular Structure; Stereoisomerism

2011
Highly enantioselective direct vinylogous Michael addition of γ-butenolide to enals.
    Organic letters, 2011, Mar-18, Volume: 13, Issue:6

    Topics: 4-Butyrolactone; Aldehydes; Catalysis; Combinatorial Chemistry Techniques; Molecular Structure; Stereoisomerism

2011
The direct asymmetric vinylogous aldol reaction of furanones with α-ketoesters: access to chiral γ-butenolides and glycerol derivatives.
    Angewandte Chemie (International ed. in English), 2011, Feb-18, Volume: 50, Issue:8

    Topics: 4-Butyrolactone; Aldehydes; Catalysis; Esters; Glycerol; Quinidine; Stereoisomerism; Tryptophan

2011
Synthesis and in vitro antitumor activity of new butenolide-containing dithiocarbamates.
    Bioorganic & medicinal chemistry letters, 2011, May-15, Volume: 21, Issue:10

    Topics: 4-Butyrolactone; Antineoplastic Agents; Cell Proliferation; Drug Design; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Molecular Structure; Structure-Activity Relationship; Thiocarbamates

2011
Syntheses of spirocyclic oxindole-butenolides by using three-component cycloadditions of isocyanides, allenoates, and isatins.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2011, Jun-27, Volume: 17, Issue:27

    Topics: 4-Butyrolactone; Cyanides; Cyclization; Indoles; Isatin; Molecular Structure; Naphthalenes; Oxindoles; Spiro Compounds; Stereoisomerism

2011
The effect of butenolide on behavioral and morphological changes in two marine fouling species, the barnacle Balanus amphitrite and the bryozoan Bugula neritina.
    Biofouling, 2011, Volume: 27, Issue:5

    Topics: 4-Butyrolactone; Animals; Bryozoa; Dose-Response Relationship, Drug; Endoplasmic Reticulum, Rough; Larva; Metamorphosis, Biological; Microscopy, Electron, Transmission; Seawater; Secretory Vesicles; Temperature; Thoracica

2011
Highly enantioselective synthesis of γ-substituted butenolides via the vinylogous Mukaiyama-Michael reaction catalyzed by a chiral scandium(III)-N,N'-dioxide complex.
    Organic & biomolecular chemistry, 2011, Aug-21, Volume: 9, Issue:16

    Topics: 4-Butyrolactone; Catalysis; Chalcone; Furans; Oxides; Scandium; Stereoisomerism

2011
Asymmetric olefin isomerization of butenolides via proton transfer catalysis by an organic molecule.
    Journal of the American Chemical Society, 2011, Aug-17, Volume: 133, Issue:32

    Topics: 4-Butyrolactone; Alkenes; Catalysis; Isomerism; Protons

2011
Regio- and stereoselective selenium dioxide allylic oxidation of (E)-dialkyl alkylidenesuccinates to (Z)-allylic alcohols: synthesis of natural and unnatural butenolides.
    Organic & biomolecular chemistry, 2011, Sep-21, Volume: 9, Issue:18

    Topics: 4-Butyrolactone; Oxidation-Reduction; Propanols; Selenium Compounds; Selenium Oxides; Stereoisomerism; Succinates

2011
Paracaseolide A, first α-alkylbutenolide dimer with an unusual tetraquinane oxa-cage bislactone skeleton from Chinese mangrove Sonneratia paracaseolaris.
    Organic letters, 2011, Oct-07, Volume: 13, Issue:19

    Topics: 4-Butyrolactone; Dimerization; Lythraceae; Models, Molecular; Molecular Structure

2011
Cis-trans photoisomerization properties of GFP chromophore analogs.
    European biophysics journal : EBJ, 2011, Volume: 40, Issue:11

    Topics: 4-Butyrolactone; Color; Green Fluorescent Proteins; Magnetic Resonance Spectroscopy; Optical Phenomena; Photochemical Processes; Pyrroles; Stereoisomerism

2011
Acute toxicity of the antifouling compound butenolide in non-target organisms.
    PloS one, 2011, Volume: 6, Issue:8

    Topics: 4-Butyrolactone; Animals; Aquatic Organisms; Biofouling; Cell Line, Tumor; Embryo, Nonmammalian; Humans; Toxicity Tests, Acute; Zebrafish

2011
Synthesis and biological activity of desmethoxy analogues of coruscanone A.
    Bioorganic & medicinal chemistry letters, 2011, Oct-15, Volume: 21, Issue:20

    Topics: 4-Butyrolactone; Animals; Antifungal Agents; Candida; Candidiasis; Cell Line; Cell Line, Tumor; Cyclopentanes; Humans; Mice; Microbial Sensitivity Tests; Structure-Activity Relationship

2011
Study of embryotoxicity of Fusarium mycotoxin butenolide using a whole rat embryo culture model.
    Toxicology in vitro : an international journal published in association with BIBRA, 2011, Volume: 25, Issue:8

    Topics: 3T3 Cells; 4-Butyrolactone; Animals; Cell Differentiation; Cell Survival; Crown-Rump Length; Embryo, Mammalian; Embryonic Development; Fusarium; Head; Mice; Mycotoxins; Rats; Rats, Wistar; Somites; Teratogens

2011
Total synthesis and absolute configuration of avenolide, extracellular factor in Streptomyces avermitilis.
    The Journal of antibiotics, 2011, Volume: 64, Issue:12

    Topics: 4-Butyrolactone; Magnetic Resonance Spectroscopy; Spectrometry, Mass, Fast Atom Bombardment; Spectrophotometry, Infrared; Stereoisomerism; Streptomyces; Structure-Activity Relationship

2011
Carboxylate-directed tandem functionalisations of α,β-dihaloalkenoic acids with 1-alkynes: a straightforward access to (Z)-configured, α,β-substituted γ-alkylidenebutenolides.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2011, Dec-02, Volume: 17, Issue:49

    Topics: 4-Butyrolactone; Alkynes; Carboxylic Acids; Catalysis; Hydrocarbons, Halogenated; Molecular Structure; Stereoisomerism

2011
Specialisation within the DWARF14 protein family confers distinct responses to karrikins and strigolactones in Arabidopsis.
    Development (Cambridge, England), 2012, Volume: 139, Issue:7

    Topics: 4-Butyrolactone; Alleles; Arabidopsis; Arabidopsis Proteins; Furans; Gene Expression Regulation, Plant; Hydrolases; Lactones; Light; Models, Biological; Mutation; Phenotype; Phylogeny; Plant Growth Regulators; Plant Physiological Phenomena; Pyrans; Signal Transduction

2012
Butenolide inhibits marine fouling by altering the primary metabolism of three target organisms.
    ACS chemical biology, 2012, Jun-15, Volume: 7, Issue:6

    Topics: 4-Butyrolactone; Acetyl-CoA C-Acetyltransferase; Acyl Coenzyme A; Acyl-CoA Dehydrogenases; Animals; Biofouling; Bryozoa; Larva; Models, Molecular; Thoracica; Vibrio

2012
A protocol for an asymmetric synthesis of γ-amino acids.
    The Journal of organic chemistry, 2012, Jul-20, Volume: 77, Issue:14

    Topics: 4-Butyrolactone; Amino Acids; Molecular Structure; Stereoisomerism

2012
Volatile lactones from streptomycetes arise via the antimycin biosynthetic pathway.
    Chembiochem : a European journal of chemical biology, 2012, Jul-23, Volume: 13, Issue:11

    Topics: 4-Butyrolactone; Antimycin A; Biosynthetic Pathways; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Molecular Structure; Spectrometry, Mass, Electrospray Ionization; Streptomyces

2012
The butenolide signaling molecules SRB1 and SRB2 induce lankacidin and lankamycin production in Streptomyces rochei.
    Chembiochem : a European journal of chemical biology, 2012, Jul-09, Volume: 13, Issue:10

    Topics: 4-Butyrolactone; Erythromycin; Isomerism; Macrolides; Magnetic Resonance Spectroscopy; Molecular Conformation; Streptomyces

2012
Sinularones A-I, new cyclopentenone and butenolide derivatives from a marine soft coral Sinularia sp. and their antifouling activity.
    Marine drugs, 2012, Volume: 10, Issue:6

    Topics: 4-Butyrolactone; Animals; Anthozoa; Antineoplastic Agents; Cell Line, Tumor; Circular Dichroism; Cyclopentanes; Humans; Magnetic Resonance Spectroscopy; Thoracica

2012
Karrikins force a rethink of strigolactone mode of action.
    Plant signaling & behavior, 2012, Volume: 7, Issue:8

    Topics: 4-Butyrolactone; Arabidopsis; Arabidopsis Proteins; Furans; Hydrolases; Hypocotyl; Lactones; Pyrans; Structure-Activity Relationship

2012
Structural optimization and evaluation of butenolides as potent antifouling agents: modification of the side chain affects the biological activities of compounds.
    Biofouling, 2012, Volume: 28, Issue:8

    Topics: 4-Butyrolactone; Animals; Biofouling; Bryozoa; Larva; Structure-Activity Relationship; Thoracica

2012
Highly enantio- and diastereoselective reactions of γ-substituted butenolides through direct vinylogous conjugate additions.
    Angewandte Chemie (International ed. in English), 2012, Oct-01, Volume: 51, Issue:40

    Topics: 4-Butyrolactone; Catalysis; Molecular Structure; Stereoisomerism; Vinyl Compounds

2012
Molecular aspects of the antagonistic interaction of smoke-derived butenolides on the germination process of Grand Rapids lettuce (Lactuca sativa) achenes.
    The New phytologist, 2012, Volume: 196, Issue:4

    Topics: 4-Butyrolactone; Abscisic Acid; Dose-Response Relationship, Drug; Fires; Furans; Gene Expression Profiling; Gene Expression Regulation, Plant; Germination; Lactuca; Plant Dormancy; Plant Growth Regulators; Pyrans; Reproducibility of Results; Seeds; Smoke

2012
Catalytic asymmetric direct vinylogous Michael addition of deconjugated butenolides to maleimides for the construction of quaternary stereogenic centers.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2012, Nov-26, Volume: 18, Issue:48

    Topics: 4-Butyrolactone; Catalysis; Maleimides; Molecular Structure; Stereoisomerism; Succinimides

2012
Antibacterial butenolides from the Korean tunicate Pseudodistoma antinboja.
    Journal of natural products, 2012, Dec-28, Volume: 75, Issue:12

    Topics: 4-Butyrolactone; Acetamides; Animals; Anti-Bacterial Agents; Drug Resistance, Bacterial; Gram-Positive Bacteria; Linezolid; Marine Biology; Microbial Sensitivity Tests; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oxazolidinones; Republic of Korea; Urochordata; Vancomycin

2012
Ramariolides A-D, antimycobacterial butenolides isolated from the mushroom Ramaria cystidiophora.
    Journal of natural products, 2012, Dec-28, Volume: 75, Issue:12

    Topics: 4-Butyrolactone; Acinetobacter; Agaricales; Animals; Anti-Bacterial Agents; Antitubercular Agents; Escherichia coli; Gram-Positive Bacteria; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium smegmatis; Mycobacterium tuberculosis; Nuclear Magnetic Resonance, Biomolecular; Pseudomonas aeruginosa; Salmonella typhimurium

2012
An efficient and facile synthesis of 3-amino-5-chromenyl-butenolides from 3-formyl chromone, dialkyl acetylenedicarboxylate, and primary amines.
    Molecular diversity, 2013, Volume: 17, Issue:1

    Topics: 4-Butyrolactone; Alkynes; Amines; Chromones; Cyanides; Fatty Acids, Unsaturated

2013
Crystal structures of two phytohormone signal-transducing α/β hydrolases: karrikin-signaling KAI2 and strigolactone-signaling DWARF14.
    Cell research, 2013, Volume: 23, Issue:3

    Topics: 4-Butyrolactone; Arabidopsis Proteins; Furans; Hydrolases; Lactones; Plant Growth Regulators; Protein Structure, Secondary; Pyrans; Signal Transduction

2013
Catalytic enantioselective vinylogous Mukaiyama-Michael addition of 2-silyloxyfurans to cyclic unsaturated oxo esters.
    The Journal of organic chemistry, 2013, Mar-15, Volume: 78, Issue:6

    Topics: 4-Butyrolactone; Catalysis; Copper; Furans; Lactones; Molecular Structure; Stereoisomerism

2013
Aspulvinones from a mangrove rhizosphere soil-derived fungus Aspergillus terreus Gwq-48 with anti-influenza A viral (H1N1) activity.
    Bioorganic & medicinal chemistry letters, 2013, Mar-15, Volume: 23, Issue:6

    Topics: 4-Butyrolactone; Animals; Antiviral Agents; Aspergillus; Benzylidene Compounds; Binding Sites; Catalytic Domain; Cell Line; Cell Survival; Dogs; Humans; Influenza A Virus, H1N1 Subtype; Magnetic Resonance Spectroscopy; Molecular Conformation; Molecular Docking Simulation; Neuraminidase; Rhizosphere; Soil Microbiology

2013
Development of metal/organo catalytic systems for direct vinylogous Michael reactions to build chiral γ,γ-disubstituted butenolides.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2013, Apr-08, Volume: 19, Issue:15

    Topics: 4-Butyrolactone; Catalysis; Ketones; Molecular Structure; Organometallic Compounds; Stereoisomerism

2013
Butanolides from methanolic extract of Litsea glutinosa.
    Chemistry & biodiversity, 2013, Volume: 10, Issue:3

    Topics: 4-Butyrolactone; Litsea; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methanol; Molecular Conformation; Plant Extracts

2013
Selective syntheses of Δ(α,β) and Δ(β,γ) butenolides from allylic cyclopropenecarboxylates via tandem ring expansion/[3,3]-sigmatropic rearrangements.
    Organic letters, 2013, Apr-05, Volume: 15, Issue:7

    Topics: 4-Butyrolactone; Catalysis; Cyclopropanes; Esters; Molecular Structure; Rhodium; Stereoisomerism

2013
iTRAQ-based proteomic profiling of the barnacle Balanus amphitrite in response to the antifouling compound meleagrin.
    Journal of proteome research, 2013, May-03, Volume: 12, Issue:5

    Topics: 4-Butyrolactone; Animals; Arthropod Proteins; Biofouling; Gene Expression; Larva; Ovomucin; Pesticides; Polymers; Proteome; Proteomics; Thoracica

2013
Mechanism and selectivity of bioinspired cinchona alkaloid derivatives catalyzed asymmetric olefin isomerization: a computational study.
    Journal of the American Chemical Society, 2013, May-22, Volume: 135, Issue:20

    Topics: 4-Butyrolactone; Alkenes; Biocatalysis; Biomimetics; Catalysis; Cinchona Alkaloids; Molecular Structure; Quantum Theory; Stereoisomerism

2013
Direct catalytic asymmetric vinylogous Mannich-type reaction of γ-butenolides with ketimines.
    Angewandte Chemie (International ed. in English), 2013, Jul-08, Volume: 52, Issue:28

    Topics: 4-Butyrolactone; Catalysis; Imines; Ketones; Lewis Acids; Nitriles; Oxidation-Reduction; Stereoisomerism

2013
Asperterrestide A, a cytotoxic cyclic tetrapeptide from the marine-derived fungus Aspergillus terreus SCSGAF0162.
    Journal of natural products, 2013, Jun-28, Volume: 76, Issue:6

    Topics: 4-Butyrolactone; Alkaloids; Antineoplastic Agents; Antiviral Agents; Aspergillus; China; Chromatography, High Pressure Liquid; Drug Screening Assays, Antitumor; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Marine Biology; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Peptides, Cyclic

2013
Alpha, beta-unsaturated lactones 2-furanone and 2-pyrone induce cellular DNA damage, formation of topoisomerase I- and II-DNA complexes and cancer cell death.
    Toxicology letters, 2013, Sep-12, Volume: 222, Issue:1

    Topics: 4-Butyrolactone; Annexin A5; Apoptosis; BRCA2 Protein; Cell Death; Cell Line, Tumor; Cell Proliferation; Comet Assay; DNA Damage; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA, Neoplasm; Enzyme Inhibitors; Fluorescein-5-isothiocyanate; Fluorescent Antibody Technique; Fluorescent Dyes; Humans; K562 Cells; Pyrones; Tetrazolium Salts; Thiazoles

2013
Total synthesis of enantiopure pyrrhoxanthin: alternative methods for the stereoselective preparation of 4-alkylidenebutenolides.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2013, Sep-23, Volume: 19, Issue:39

    Topics: 4-Butyrolactone; Biological Products; Carotenoids; Stereoisomerism

2013
Total synthesis of (+)-clavilactone A and (-)-clavilactone B by ring-opening/ring-closing metathesis.
    Organic letters, 2013, Nov-01, Volume: 15, Issue:21

    Topics: 4-Butyrolactone; Catalysis; Cyclobutanes; Lactones; Molecular Structure; Stereoisomerism

2013
Reactivity umpolung in intramolecular ring closure of 3,4-disubstituted butenolides: diastereoselective total synthesis of paeonilide.
    Organic letters, 2013, Nov-15, Volume: 15, Issue:22

    Topics: 4-Butyrolactone; Cyclization; Molecular Structure; Stereoisomerism; Terpenes

2013
Isolation of a new butenolide from the South China Sea gorgonian coral Subergorgia suberosa.
    Natural product research, 2014, Volume: 28, Issue:3

    Topics: 4-Butyrolactone; Animals; Anthozoa; Dose-Response Relationship, Drug; Larva; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oceans and Seas; Thoracica; Water Pollutants, Chemical

2014
Catalytic, asymmetric synthesis of phosphonic γ-(hydroxyalkyl)butenolides with contiguous quaternary and tertiary stereogenic centers.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2014, Feb-03, Volume: 20, Issue:6

    Topics: 4-Butyrolactone; Catalysis; Organophosphonates; Stereoisomerism

2014
Asymmetric vinylogous Mannich reaction of silyloxy furans with N-tert-butanesulfinyl ketimines.
    Organic letters, 2014, Feb-07, Volume: 16, Issue:3

    Topics: 4-Butyrolactone; Catalysis; Furans; Imines; Indoles; Molecular Structure; Nitriles; Stereoisomerism; Sulfonium Compounds

2014
Comparative safety of the antifouling compound butenolide and 4,5-dichloro-2-n-octyl-4-isothiazolin-3-one (DCOIT) to the marine medaka (Oryzias melastigma).
    Aquatic toxicology (Amsterdam, Netherlands), 2014, Volume: 149

    Topics: 4-Butyrolactone; Acetylcholinesterase; Animals; Biomarkers; Enzyme Activation; Estradiol; Female; Liver; Male; Oryzias; Oxidative Stress; Synaptic Transmission; Testosterone; Thiazoles; Water Pollutants, Chemical

2014
Two new butenolides produced by an Actinomycete Streptomyces sp.
    Chemistry & biodiversity, 2014, Volume: 11, Issue:6

    Topics: 4-Butyrolactone; Actinobacteria; Antifungal Agents; Dose-Response Relationship, Drug; Fungi; Microbial Sensitivity Tests; Molecular Conformation; Structure-Activity Relationship

2014
New amino butenolides from the bulbs of Fritillaria unibracteata.
    Fitoterapia, 2014, Volume: 98

    Topics: 4-Butyrolactone; Amines; Cell Line, Tumor; Fritillaria; Hepatocytes; Humans; Molecular Structure; Plant Roots

2014
2(5H)-Furanone, epigallocatechin gallate, and a citric-based disinfectant disturb quorum-sensing activity and reduce motility and biofilm formation of Campylobacter jejuni.
    Folia microbiologica, 2015, Volume: 60, Issue:1

    Topics: 4-Butyrolactone; Biofilms; Campylobacter jejuni; Catechin; Citric Acid; Disinfectants; Microbial Sensitivity Tests; Quorum Sensing

2015
Chemoselective synthesis of trifluoromethylated γ-butenolide derivatives via phosphine-promoted tandem reaction of allylic carbonates and trifluoromethyl ketones.
    Organic letters, 2014, Oct-17, Volume: 16, Issue:20

    Topics: 4-Butyrolactone; Carbonates; Catalysis; Hydrocarbons, Fluorinated; Ketones; Molecular Structure; Phosphines; Stereoisomerism

2014
Sinulolides A-H, new cyclopentenone and butenolide derivatives from soft coral Sinularia sp.
    Marine drugs, 2014, Oct-23, Volume: 12, Issue:10

    Topics: 4-Butyrolactone; Animals; Anthozoa; Circular Dichroism; Cyclopentanes; NF-kappa B

2014
Total synthesis of muricadienin, the putative key precursor in the solamin biosynthesis.
    Organic letters, 2014, Nov-21, Volume: 16, Issue:22

    Topics: 4-Butyrolactone; Acetogenins; Cyclization; Furans; Molecular Structure; Stereoisomerism

2014
Proteomic changes in brain tissues of marine medaka (Oryzias melastigma) after chronic exposure to two antifouling compounds: butenolide and 4,5-dichloro-2-n-octyl-4-isothiazolin-3-one (DCOIT).
    Aquatic toxicology (Amsterdam, Netherlands), 2014, Volume: 157

    Topics: 4-Butyrolactone; Animals; Brain; Environmental Exposure; Female; Gene Expression Regulation; Male; Mitogen-Activated Protein Kinases; Oryzias; Proteomics; Sex Factors; Signal Transduction; Thiazoles; Water Pollutants, Chemical

2014
Degradation kinetics of a potent antifouling agent, butenolide, under various environmental conditions.
    Chemosphere, 2015, Volume: 119

    Topics: 4-Butyrolactone; Animals; Bacteria; Biodegradation, Environmental; Diatoms; Half-Life; Kinetics; Larva; Photolysis; Seawater; Thiazoles; Thoracica; Water Microbiology

2015
Donor-acceptor substituted cyclopropane to butanolide and butenolide natural products: enantiospecific first total synthesis of (+)-hydroxyancepsenolide.
    Organic letters, 2014, Dec-19, Volume: 16, Issue:24

    Topics: 4-Butyrolactone; Antimycin A; Biological Products; Cyclopropanes; Dioxoles; Lactones; Molecular Structure; Stereoisomerism

2014
Singlet-oxygen oxidation of 5-hydroxymethylfurfural in continuous flow.
    ChemSusChem, 2015, May-22, Volume: 8, Issue:10

    Topics: 4-Butyrolactone; Furaldehyde; Light; Oxidation-Reduction; Photosensitizing Agents; Rose Bengal; Singlet Oxygen

2015
Effect of smoke derivatives on in vitro pollen germination and pollen tube elongation of species from different plant families.
    Plant biology (Stuttgart, Germany), 2015, Volume: 17, Issue:4

    Topics: 4-Butyrolactone; Culture Media; Furans; Liliaceae; Pollen; Pollen Tube; Pyrans; Smoke; Water

2015
A novel derivatization procedure and chiral gas chromatographic method for enantiomeric purity screening of L-carnitine.
    Acta chimica Slovenica, 2014, Volume: 61, Issue:4

    Topics: 4-Butyrolactone; Carnitine; Chemistry Techniques, Analytical; Chromatography, Gas; Chromatography, High Pressure Liquid; Cyclodextrins; Dietary Supplements; Lactones; Models, Chemical; Stereoisomerism; Time Factors

2014
Hepatic proteomic responses in marine medaka (Oryzias melastigma) chronically exposed to antifouling compound butenolide [5-octylfuran-2(5H)-one] or 4,5-dichloro-2-N-octyl-4-isothiazolin-3-one (DCOIT).
    Environmental science & technology, 2015, Feb-03, Volume: 49, Issue:3

    Topics: 4-Butyrolactone; Animals; Biomarkers; Cytochrome P-450 Enzyme System; Endocrine Disruptors; Female; Glucuronosyltransferase; Glutathione Transferase; Liver; Male; Oryzias; Proteomics; Thiazoles; Vitellogenins; Water Pollutants, Chemical

2015
Design and Synthesis of Butenolide-based Novel Benzyl Pyrrolones: Their TNF-α based Molecular Docking with In vivo and In vitro Anti-inflammatory Activity.
    Chemical biology & drug design, 2015, Volume: 86, Issue:4

    Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Drug Design; Drug Evaluation, Preclinical; Female; Lipid Peroxidation; Liver; Male; Mice; Molecular Docking Simulation; Rats; Stomach Ulcer; Structure-Activity Relationship; Tumor Necrosis Factor-alpha

2015
A new butenolide cinnamate and other biological active chemical constituents from Polygonum glabrum.
    Natural product research, 2015, Volume: 29, Issue:22

    Topics: 4-Butyrolactone; Anti-Bacterial Agents; Anti-HIV Agents; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cinnamates; HIV-1; Humans; Molecular Structure; Mycobacterium tuberculosis; Phytochemicals; Plant Components, Aerial; Plant Extracts; Polygonum

2015
Regiodivergent Lewis base-promoted O- to C-carboxyl transfer of furanyl carbonates.
    Organic & biomolecular chemistry, 2015, Mar-14, Volume: 13, Issue:10

    Topics: 4-Aminopyridine; 4-Butyrolactone; Carbon; Carbonates; Catalysis; Furans; Kinetics; Lewis Bases; Magnetic Resonance Spectroscopy; Molecular Structure; Oxygen; Stereoisomerism

2015
[Genes for biosynthesis of butenolide-like signalling molecules in Streptomyces ghanaensis, their role in moenomycin production].
    Genetika, 2014, Volume: 50, Issue:6

    Topics: 4-Butyrolactone; Genes, Bacterial; Mutation; Oligosaccharides; Signal Transduction; Streptomyces

2014
Direct Enantioselective Vinylogous Mannich Reaction of Ketimines with γ-Butenolide by Using Cinchona Alkaloid Amide/Zinc(II) Catalysts.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2015, Jun-26, Volume: 21, Issue:27

    Topics: 4-Butyrolactone; Amides; Cinchona Alkaloids; Imines; Mesylates; Molecular Structure; Nitriles; Stereoisomerism

2015
Diastereodivergent and Enantioselective [4+2] Annulations of γ-Butenolides with Cyclic 1-Azadienes.
    Molecules (Basel, Switzerland), 2015, Jul-27, Volume: 20, Issue:8

    Topics: 4-Butyrolactone; Stereoisomerism

2015
Terrenolide S, a new antileishmanial butenolide from the endophytic fungus Aspergillus terreus.
    Natural product research, 2016, Volume: 30, Issue:7

    Topics: 4-Butyrolactone; Antiprotozoal Agents; Aspergillus; Endophytes; Leishmania donovani; Methicillin-Resistant Staphylococcus aureus; Molecular Structure

2016
Asymmetric Total Synthesis of (-)-Kravanhin B.
    Chemistry, an Asian journal, 2015, Volume: 10, Issue:12

    Topics: 4-Butyrolactone; Aldehydes; Catalysis; Cyclization; Cyclohexane Monoterpenes; Diterpenes; Monoterpenes; Stereoisomerism

2015
A Synthetic Butenolide Diterpene is now a Natural Product Isolated from Metaporana sericosepala, a Plant from the Madagascar Dry Forest.
    Natural product communications, 2015, Volume: 10, Issue:9

    Topics: 4-Butyrolactone; Biological Products; Climate; Convolvulaceae; Diterpenes; Forests; Madagascar; Molecular Structure

2015
Imprint Desorption Electrospray Ionization Mass Spectrometry Imaging for Monitoring Secondary Metabolites Production during Antagonistic Interaction of Fungi.
    Analytical chemistry, 2015, Dec-15, Volume: 87, Issue:24

    Topics: 4-Butyrolactone; Agaricales; Biological Products; Butanes; Coculture Techniques; Cyclohexanones; Lactones; Secondary Metabolism; Spectrometry, Mass, Electrospray Ionization; Trichoderma

2015
Polyketide butenolide, diphenyl ether, and benzophenone derivatives from the fungus Aspergillus flavipes PJ03-11.
    Bioorganic & medicinal chemistry letters, 2016, Jan-15, Volume: 26, Issue:2

    Topics: 4-Butyrolactone; alpha-Glucosidases; Aspergillus; Benzophenones; Glycoside Hydrolase Inhibitors; Phenyl Ethers; Polyketides; Saccharomyces cerevisiae

2016
Butenolide derivatives from the plant endophytic fungus Aspergillus terreus.
    Fitoterapia, 2016, Volume: 113

    Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Aspergillus; Camellia sinensis; Endophytes; HL-60 Cells; Humans; Mice; Molecular Structure; Nitric Oxide; RAW 264.7 Cells

2016
(4R,6S)-2-Dihydromenisdaurilide is a Butenolide that Efficiently Inhibits Hepatitis C Virus Entry.
    Scientific reports, 2016, 07-18, Volume: 6

    Topics: 4-Butyrolactone; Adsorption; Antiviral Agents; Cell Line, Tumor; Enzyme-Linked Immunosorbent Assay; Hepacivirus; Hepatitis C; Humans; Immunity; Microscopy, Confocal; Phyllanthus; Reproducibility of Results; Virion; Virus Activation; Virus Internalization

2016
Ligubenzocycloheptanone A, a Novel Tricyclic Butenolide with a 6/7/5 Skeleton from Ligusticum chuanxiong.
    Scientific reports, 2016, 07-27, Volume: 6

    Topics: 4-Butyrolactone; Circular Dichroism; Crystallography; Free Radical Scavengers; Ligusticum; Magnetic Resonance Spectroscopy; Spectrometry, Mass, Secondary Ion; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; X-Ray Diffraction

2016
An histidine covalent receptor and butenolide complex mediates strigolactone perception.
    Nature chemical biology, 2016, Volume: 12, Issue:10

    Topics: 4-Butyrolactone; Heterocyclic Compounds, 3-Ring; Histidine; Lactones; Ligands; Molecular Structure; Pisum sativum; Plant Growth Regulators; Plant Proteins

2016
Characterization of AvaR1, a butenolide-autoregulator receptor for biosynthesis of a Streptomyces hormone in Streptomyces avermitilis.
    Applied microbiology and biotechnology, 2016, Volume: 100, Issue:22

    Topics: 4-Butyrolactone; Bacterial Proteins; Gene Expression Regulation, Bacterial; Gene Knockout Techniques; Ivermectin; Receptors, Cell Surface; Repressor Proteins; Streptomyces; Transcription, Genetic

2016
A Unique Mdm2-Binding Mode of the 3-Pyrrolin-2-one- and 2-Furanone-Based Antagonists of the p53-Mdm2 Interaction.
    ACS chemical biology, 2016, 12-16, Volume: 11, Issue:12

    Topics: 4-Butyrolactone; Crystallography, X-Ray; Drug Design; Humans; Models, Molecular; Protein Conformation; Protein Interaction Maps; Protein Multimerization; Proto-Oncogene Proteins c-mdm2; Pyrroles; Structure-Activity Relationship; Tumor Suppressor Protein p53

2016
Three New Butenolides from the Fungus Aspergillus sp. CBS-P-2.
    Molecules (Basel, Switzerland), 2016, Oct-13, Volume: 21, Issue:10

    Topics: 4-Butyrolactone; Anti-Infective Agents; Antineoplastic Agents; Antioxidants; Aspergillus; Cell Line, Tumor; Cell Proliferation; Cell Survival; Circular Dichroism; HCT116 Cells; HL-60 Cells; Humans; Microbial Sensitivity Tests; Molecular Structure; Staphylococcus aureus

2016
Cadiolides J-M, antibacterial polyphenyl butenolides from the Korean tunicate Pseudodistoma antinboja.
    Bioorganic & medicinal chemistry letters, 2017, 02-01, Volume: 27, Issue:3

    Topics: 4-Butyrolactone; Animals; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Gram-Positive Bacteria; Microbial Sensitivity Tests; Molecular Structure; Republic of Korea; Structure-Activity Relationship; Urochordata

2017
Influence of twitching and swarming motilities on biofilm formation in Pseudomonas strains.
    Archives of microbiology, 2017, Volume: 199, Issue:5

    Topics: 4-Butyrolactone; Bacterial Adhesion; Biofilms; Fimbriae, Bacterial; Pseudomonas aeruginosa; Pseudomonas Infections; Virulence Factors

2017
γ-Butenolide and furanone derivatives from the soil-derived fungus Aspergillus sclerotiorum PSU-RSPG178.
    Phytochemistry, 2017, Volume: 137

    Topics: 4-Butyrolactone; Animals; Anti-Bacterial Agents; Aspergillus; Chlorocebus aethiops; Escherichia coli; Humans; MCF-7 Cells; Molecular Structure; Plasmodium falciparum; Soil Microbiology; Staphylococcus aureus; Thailand; Vero Cells

2017
Total Synthesis and Structural Revision of Clavilactone D.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2017, Mar-17, Volume: 23, Issue:16

    Topics: 4-Butyrolactone; Basidiomycota; Biological Products; Cyclobutanes; Lactones; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Stereoisomerism

2017
Field evaluation of Cucurbit yellow stunting disorder virus transmission by Bemisia tabaci.
    Virus research, 2017, 09-15, Volume: 241

    Topics: 4-Butyrolactone; Animals; Crinivirus; Cucurbitaceae; Guanidines; Hemiptera; Insect Vectors; Insecticides; Neonicotinoids; Nitro Compounds; ortho-Aminobenzoates; Plant Diseases; Pyrazoles; Pyridines

2017
Synthesis of tricyclic butenolides and comparison their effects with known smoke-butenolide, KAR1.
    Journal of plant physiology, 2017, Volume: 215

    Topics: 4-Butyrolactone; Avena; Cotyledon; Furans; Germination; Pyrans; Seedlings; Seeds

2017
Late-stage divergent synthesis and antifouling activity of geraniol-butenolide hybrid molecules.
    Organic & biomolecular chemistry, 2017, Jul-05, Volume: 15, Issue:26

    Topics: 4-Butyrolactone; Acyclic Monoterpenes; Animals; Biofouling; Dose-Response Relationship, Drug; Molecular Structure; Structure-Activity Relationship; Terpenes; Thoracica

2017
Synthesis of the Marine Myxobacterial Antibiotic Enhygrolide A.
    Journal of natural products, 2017, 07-28, Volume: 80, Issue:7

    Topics: 4-Butyrolactone; Aldehydes; Alkylation; Anti-Bacterial Agents; Benzylidene Compounds; Catalysis; Marine Biology; Molecular Structure; Myxococcales; Stereoisomerism

2017
Total Synthesis of the Schisandraceae Nortriterpenoid Rubriflordilactone A.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2017, Oct-09, Volume: 23, Issue:56

    Topics: 4-Butyrolactone; Catalysis; Cobalt; Cyclization; Magnetic Resonance Spectroscopy; Palladium; Schisandraceae; Stereoisomerism; Triterpenes

2017
Aruncin B: Synthetic Studies, Structural Reassignment and Biological Evaluation.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2017, Nov-21, Volume: 23, Issue:65

    Topics: 4-Butyrolactone; Alkenes; Cell Proliferation; Humans; Jurkat Cells; Molecular Conformation; Pyrans; Stereoisomerism

2017
Identification of butenolide regulatory system controlling secondary metabolism in Streptomyces albus J1074.
    Scientific reports, 2017, 08-29, Volume: 7, Issue:1

    Topics: 4-Butyrolactone; Chromatography, Liquid; Gene Expression Regulation, Fungal; Genes, Fungal; Hormones; Mass Spectrometry; Multigene Family; Mutation; Secondary Metabolism; Streptomyces; Transcription, Genetic

2017
Metabolites from the Plant Endophytic Fungus Aspergillus sp. CPCC 400735 and Their Anti-HIV Activities.
    Journal of natural products, 2017, 10-27, Volume: 80, Issue:10

    Topics: 4-Butyrolactone; Anti-HIV Agents; Aspergillus; China; Cytochalasins; Diterpenes; Endophytes; Inhibitory Concentration 50; Kadsura; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Phenalenes

2017
Lactones from the Sponge-Derived Fungus Talaromyces rugulosus.
    Marine drugs, 2017, Nov-14, Volume: 15, Issue:11

    Topics: 4-Butyrolactone; Animals; Biological Products; Cell Line, Tumor; Circular Dichroism; Lactones; Leukemia L5178; Mice; Nuclear Magnetic Resonance, Biomolecular; Porifera; Talaromyces

2017
New butenolide derivatives from the marine sponge-derived fungus Aspergillus terreus.
    Bioorganic & medicinal chemistry letters, 2018, 02-01, Volume: 28, Issue:3

    Topics: 4-Butyrolactone; alpha-Glucosidases; Antioxidants; Aspergillus; Biphenyl Compounds; Density Functional Theory; Dose-Response Relationship, Drug; Glycoside Hydrolase Inhibitors; Molecular Structure; Picrates; Structure-Activity Relationship

2018
Anti-biofilm effect of a butenolide/polymer coating and metatranscriptomic analyses.
    Biofouling, 2018, Volume: 34, Issue:1

    Topics: 4-Butyrolactone; Biofilms; Biofouling; Cell Adhesion; Metagenomics; Microbial Consortia; Polyesters; Polyurethanes; Seawater; Surface Properties; Transcriptome

2018
Spongian diterpenes from Chinese marine sponge Spongia officinalis.
    Fitoterapia, 2018, Volume: 127

    Topics: 4-Butyrolactone; Animals; China; Diterpenes; Furans; Molecular Structure; Porifera

2018
Butenolides from Streptomyces albus J1074 Act as External Signals To Stimulate Avermectin Production in Streptomyces avermitilis.
    Applied and environmental microbiology, 2018, 05-01, Volume: 84, Issue:9

    Topics: 4-Butyrolactone; Bacterial Proteins; Gene Expression; Ivermectin; Mass Spectrometry; Metabolome; Secondary Metabolism; Species Specificity; Streptomyces

2018
Lethal and sublethal toxicity of neonicotinoid and butenolide insecticides to the mayfly, Hexagenia spp.
    Environmental pollution (Barking, Essex : 1987), 2018, Volume: 238

    Topics: 4-Butyrolactone; Animals; Ephemeroptera; Guanidines; Imidazoles; Insecticides; Larva; Neonicotinoids; Nitro Compounds; Oxazines; Pyridines; Thiamethoxam; Thiazines; Thiazoles

2018
Direct Catalytic Asymmetric Vinylogous Additions of α,β- and β,γ-Butenolides to Polyfluorinated Alkynyl Ketimines.
    Angewandte Chemie (International ed. in English), 2018, 08-27, Volume: 57, Issue:35

    Topics: 4-Butyrolactone; Alkynes; Catalysis; Chemistry Techniques, Synthetic; Halogenation; Hydrocarbons, Fluorinated; Imines; Methylation; Nitriles; Stereoisomerism

2018
Total Synthesis of γ-Alkylidenebutenolides, Potent Melanogenesis Inhibitors from Thai Medicinal Plant Melodorum fruticosum.
    The Journal of organic chemistry, 2018, 08-03, Volume: 83, Issue:15

    Topics: 4-Butyrolactone; Animals; Annonaceae; Cell Line, Tumor; Chemistry Techniques, Synthetic; Melanins; Mice; Plants, Medicinal

2018
Bioactive secondary metabolites from the marine-associated fungus Aspergillus terreus.
    Bioorganic chemistry, 2018, Volume: 80

    Topics: 4-Butyrolactone; Animals; Anthozoa; Anti-Inflammatory Agents; Aspergillus; Bacteria; Biological Products; Glycoside Hydrolase Inhibitors; Mice; Molecular Docking Simulation; Nitric Oxide; RAW 264.7 Cells; Saccharomyces cerevisiae; Secondary Metabolism; Sesquiterpenes

2018
Long-Term Effects of Cold on Growth, Development and Yield of Narrow-Leaf Lupine May Be Alleviated by Seed Hydropriming or Butenolide.
    International journal of molecular sciences, 2018, Aug-16, Volume: 19, Issue:8

    Topics: 4-Butyrolactone; alpha-Amylases; Biomass; Chlorophyll; Chlorophyll A; Cold Temperature; Electrolytes; Fluorescence; Germination; Kinetics; Lupinus; Oxidoreductases; Plant Growth Regulators; Plant Leaves; Seeds; Temperature; Time Factors

2018
Anthraquinone and Butenolide Constituents from the Crinoid Capillaster multiradiatus.
    Chemical & pharmaceutical bulletin, 2018, Nov-01, Volume: 66, Issue:11

    Topics: 4-Butyrolactone; Animals; Anthraquinones; Cyclooxygenase 2; Dose-Response Relationship, Drug; Echinodermata; Enzyme Inhibitors; Lipopolysaccharides; Mice; Molecular Structure; Nitric Oxide; Nitric Oxide Synthase Type II; RAW 264.7 Cells; Structure-Activity Relationship

2018
Terrusnolides A-D, new butenolides with anti-inflammatory activities from an endophytic Aspergillus from Tripterygium wilfordii.
    Fitoterapia, 2018, Volume: 130

    Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents; Aspergillus; China; Endophytes; Interleukin-1beta; Mice; Molecular Structure; Nitric Oxide; Plant Roots; RAW 264.7 Cells; Tripterygium; Tumor Necrosis Factor-alpha

2018
Ru(II)-Catalyzed Synthesis of Substituted Furans and Their Conversion to Butenolides.
    Organic letters, 2018, 09-21, Volume: 20, Issue:18

    Topics: 4-Butyrolactone; Catalysis; Furans; Molecular Structure; Organometallic Compounds; Ruthenium

2018
Asperimides A-D, anti-inflammatory aromatic butenolides from a tropical endophytic fungus Aspergillus terreus.
    Fitoterapia, 2018, Volume: 131

    Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents; Aspergillus; China; Circular Dichroism; Embryophyta; Endophytes; Mice; Molecular Structure; Nitric Oxide; Plant Leaves; RAW 264.7 Cells

2018
Identification of a butenolide signaling system that regulates nikkomycin biosynthesis in
    The Journal of biological chemistry, 2018, 12-28, Volume: 293, Issue:52

    Topics: 4-Butyrolactone; Aminoglycosides; Bacterial Proteins; Biosynthetic Pathways; Gene Expression Regulation, Bacterial; Genes, Bacterial; Multigene Family; Streptomyces; Transcriptional Activation

2018
Butenolides from a marine-derived fungus Aspergillus terreus with antitumor activities against pancreatic ductal adenocarcinoma cells.
    Bioorganic & medicinal chemistry, 2018, 12-01, Volume: 26, Issue:22

    Topics: 4-Butyrolactone; Antineoplastic Agents; Apoptosis; Aspergillus; Carcinoma, Pancreatic Ductal; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Pancreatic Neoplasms; Structure-Activity Relationship

2018
Cacolides: Sesterterpene Butenolides from a Southern Australian Marine Sponge,
    Marine drugs, 2018, Nov-20, Volume: 16, Issue:11

    Topics: 4-Butyrolactone; Animals; Aquatic Organisms; Australia; Biological Factors; Chemical Fractionation; Chromatography, High Pressure Liquid; Drug Discovery; Magnetic Resonance Spectroscopy; Molecular Structure; Porifera; Sesterterpenes; Tandem Mass Spectrometry

2018
Metabolites from the Paracel Islands Soft Coral
    Marine drugs, 2018, Dec-19, Volume: 16, Issue:12

    Topics: 4-Butyrolactone; Animals; Anthozoa; Cell Line, Tumor; Cyclopentanes; Cytotoxins; HCT116 Cells; HeLa Cells; Humans; Molecular Conformation; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Sesquiterpenes

2018
Toxicity and Sublethal Effects of Flupyradifurone, a Novel Butenolide Insecticide, on the Development and Fecundity of Aphis gossypii (Hemiptera: Aphididae).
    Journal of economic entomology, 2019, 03-21, Volume: 112, Issue:2

    Topics: 4-Butyrolactone; Animals; Aphids; Fertility; Insecticides; Pyridines

2019
Butenolide, a Marine-Derived Broad-Spectrum Antibiofilm Agent Against Both Gram-Positive and Gram-Negative Pathogenic Bacteria.
    Marine biotechnology (New York, N.Y.), 2019, Volume: 21, Issue:1

    Topics: 4-Butyrolactone; Anti-Bacterial Agents; Biofilms; Drug Combinations; Drug Synergism; Escherichia coli; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Microscopy, Electron, Scanning; Pseudomonas aeruginosa; Tetracycline

2019
Impairment in karrikin but not strigolactone sensing enhances root skewing in Arabidopsis thaliana.
    The Plant journal : for cell and molecular biology, 2019, Volume: 98, Issue:4

    Topics: 4-Butyrolactone; Arabidopsis; Arabidopsis Proteins; Carrier Proteins; Furans; Gene Expression Regulation, Plant; Hydrolases; Intracellular Signaling Peptides and Proteins; Lactones; Mutation; Phenotype; Plant Growth Regulators; Plant Roots; Pyrans; Signal Transduction; Transcriptome

2019
Butenolides from Nectandra oppositifolia (Lauraceae) displayed anti-Trypanosoma cruzi activity via deregulation of mitochondria.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2019, Feb-15, Volume: 54

    Topics: 4-Butyrolactone; Animals; Brazil; Cell Membrane; Chagas Disease; Humans; Lauraceae; Membrane Potential, Mitochondrial; Mitochondria; Trypanocidal Agents; Trypanosoma cruzi

2019
Hydrogen Peroxide Oxygenation of Furan-2-carbaldehyde via an Easy, Green Method.
    Journal of agricultural and food chemistry, 2019, Mar-20, Volume: 67, Issue:11

    Topics: 4-Butyrolactone; Acetic Acid; Acids; Food Preservatives; Furans; Green Chemistry Technology; Hydrogen Peroxide; Oxidation-Reduction

2019
Acute and chronic toxicity of neonicotinoid and butenolide insecticides to the freshwater amphipod, Hyalella azteca.
    Ecotoxicology and environmental safety, 2019, Jul-15, Volume: 175

    Topics: 4-Butyrolactone; Amphipoda; Animals; Fresh Water; Insecticides; Neonicotinoids; Toxicity Tests, Acute; Toxicity Tests, Chronic; Water Pollutants, Chemical

2019
Synthesis and Bio-Evaluation of Natural Butenolides-Acrylate Conjugates.
    Molecules (Basel, Switzerland), 2019, Apr-03, Volume: 24, Issue:7

    Topics: 4-Butyrolactone; Acrylates; Antifungal Agents; Biological Products; Molecular Structure; Structure-Activity Relationship

2019
Synthesis of potent neuroprotective butenolides based on plant smoke derived 3,4,5-Trimethylfuran-2(5H)-one and 3-methyl-2H-furo[2,3-c]pyrone-2-one.
    Phytochemistry, 2019, Volume: 163

    Topics: 4-Butyrolactone; Acetylcholinesterase; Depressive Disorder; Dose-Response Relationship, Drug; Furans; Humans; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neurodegenerative Diseases; Neuroprotective Agents; Pyrans; Structure-Activity Relationship

2019
Striatisporolide A, a butenolide metabolite from Athyrium multidentatum (Doll.) Ching, as a potential antibacterial agent.
    Molecular medicine reports, 2019, Volume: 20, Issue:1

    Topics: 4-Butyrolactone; Adenosine Triphosphate; Alkaline Phosphatase; Anti-Bacterial Agents; Cell Membrane; Escherichia coli; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Plant Extracts; Tracheophyta

2019
Butenolide Derivatives with α-Glucosidase Inhibitions from the Deep-Sea-Derived Fungus
    Marine drugs, 2019, Jun-03, Volume: 17, Issue:6

    Topics: 4-Butyrolactone; Acetates; Aquatic Organisms; Aspergillus; Circular Dichroism; Enzyme Activation; Glycoside Hydrolase Inhibitors; Magnetic Resonance Spectroscopy; Mass Spectrometry

2019
The novel butenolide pesticide flupyradifurone does not alter responsiveness to sucrose at either acute or chronic short-term field-realistic doses in the honey bee, Apis mellifera.
    Pest management science, 2020, Volume: 76, Issue:1

    Topics: 4-Butyrolactone; Animals; Bees; Insecticides; Neonicotinoids; Pyridines; Sucrose

2020
New butenolides with anti-inflammatory activity from
    Natural product research, 2021, Volume: 35, Issue:11

    Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents; Balanophoraceae; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; Plant Extracts; RAW 264.7 Cells

2021
Phytochemical Investigation of
    Molecules (Basel, Switzerland), 2019, Sep-13, Volume: 24, Issue:18

    Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents; Furans; Inhibitory Concentration 50; Lipopolysaccharides; Mice; Molecular Structure; Nitric Oxide; Phytochemicals; RAW 264.7 Cells; Tradescantia

2019
Synthesis of 7,6-Spirocyclic Imine with Butenolide Ring Provides Evidence for the Relative Configuration of Marine Toxin 13-desMe Spirolide C.
    Organic letters, 2019, 11-15, Volume: 21, Issue:22

    Topics: 4-Butyrolactone; Cycloaddition Reaction; Imines; Marine Toxins; Molecular Structure; Spiro Compounds; Stereoisomerism

2019
The leafcutter bee, Megachile rotundata, is more sensitive to N-cyanoamidine neonicotinoid and butenolide insecticides than other managed bees.
    Nature ecology & evolution, 2019, Volume: 3, Issue:11

    Topics: 4-Butyrolactone; Animals; Bees; Insecticides; Neonicotinoids; Pollination

2019
Octyl substituted butenolides from marine-derived
    Natural product research, 2021, Volume: 35, Issue:15

    Topics: 4-Butyrolactone; Antiviral Agents; Herpes Simplex; Magnetic Resonance Spectroscopy; Streptomyces

2021
Biosynthesis of Pseudomonas-Derived Butenolides.
    Angewandte Chemie (International ed. in English), 2020, 03-27, Volume: 59, Issue:14

    Topics: 4-Butyrolactone; Bacterial Proteins; DNA Transposable Elements; Multigene Family; Mutagenesis; Pseudomonas; Soil Microbiology

2020
Three New Butenolides from the Green Alga Caulerpa racemosa var. turbinata.
    Chemistry & biodiversity, 2020, Volume: 17, Issue:5

    Topics: 4-Butyrolactone; Acinetobacter baumannii; Anti-Bacterial Agents; Caulerpa; Dose-Response Relationship, Drug; Enterococcus faecalis; Escherichia coli; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Molecular Conformation; Pseudomonas aeruginosa; Structure-Activity Relationship

2020
Goodyschle A, a new butenolide with significant BchE inhibitory activity from
    Natural product research, 2021, Volume: 35, Issue:23

    Topics: 4-Butyrolactone; Acetylcholinesterase; Butyrylcholinesterase; Cholinesterase Inhibitors; Humans; Structure-Activity Relationship

2021
Combining a bio-based polymer and a natural antifoulant into an eco-friendly antifouling coating.
    Biofouling, 2020, Volume: 36, Issue:2

    Topics: 4-Butyrolactone; Biodegradable Plastics; Biofouling; Disinfectants; Polyesters; Polyurethanes; Seawater; Surface Properties

2020
Axl and immune checkpoints inhibitors from fruiting bodies of Pleurocybella porrigens.
    The Journal of antibiotics, 2020, Volume: 73, Issue:10

    Topics: 4-Butyrolactone; A549 Cells; Agaricales; Antineoplastic Agents; Axl Receptor Tyrosine Kinase; Fruiting Bodies, Fungal; Humans; Immune Checkpoint Inhibitors; Magnetic Resonance Spectroscopy; Molecular Structure; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases

2020
Synthesis and evaluation of heterocycle structures as potential inhibitors of Mycobacterium tuberculosis UGM.
    Bioorganic & medicinal chemistry, 2020, 07-01, Volume: 28, Issue:13

    Topics: 4-Butyrolactone; Antitubercular Agents; Drug Evaluation, Preclinical; Enzyme Inhibitors; Humans; Indoles; Intramolecular Transferases; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Mycobacterium tuberculosis; Protein Binding; Tuberculosis

2020
Determination of neonicotinoids and butenolide residues in avian and insect pollinators and their ambient environment in Western Canada (2017, 2018).
    The Science of the total environment, 2020, Oct-01, Volume: 737

    Topics: 4-Butyrolactone; Animals; Bees; British Columbia; Insecta; Insecticides; Neonicotinoids; Nitro Compounds; Saskatchewan

2020
Insect-Associated Bacteria Assemble the Antifungal Butenolide Gladiofungin by Non-Canonical Polyketide Chain Termination.
    Angewandte Chemie (International ed. in English), 2020, 12-14, Volume: 59, Issue:51

    Topics: 4-Butyrolactone; Animals; Antifungal Agents; Burkholderia; Coleoptera; Hypocreales; Microbial Sensitivity Tests; Polyketides

2020
Total synthesis of (-)-2-methoxy-2-butenolide-3-cinnamate and its antimicrobial potentials.
    Natural product research, 2021, Volume: 35, Issue:23

    Topics: 4-Butyrolactone; Anti-Bacterial Agents; Cinnamates; Microbial Sensitivity Tests

2021
New cytotoxic secondary metabolites against human pancreatic cancer cells from the Hypericum perforatum endophytic fungus Aspergillus terreus.
    Fitoterapia, 2020, Volume: 146

    Topics: 4-Butyrolactone; Antineoplastic Agents; Aspergillus; Cell Line, Tumor; China; Flowers; Humans; Hypericum; Lovastatin; Pancreatic Neoplasms

2020
Functional Analysis of P450 Monooxygenase SrrO in the Biosynthesis of Butenolide-Type Signaling Molecules in
    Biomolecules, 2020, 08-25, Volume: 10, Issue:9

    Topics: 4-Butyrolactone; Anti-Bacterial Agents; Bacterial Proteins; Biosynthetic Pathways; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Erythromycin; Genes, Bacterial; Macrolides; Magnetic Resonance Spectroscopy; Molecular Structure; Mutation; Signal Transduction; Spectrometry, Mass, Electrospray Ionization; Streptomyces

2020
Synthesis and Biological Evaluation of Analogues of Butyrolactone I as PTP1B Inhibitors.
    Marine drugs, 2020, Oct-23, Volume: 18, Issue:11

    Topics: 4-Butyrolactone; Cell Line; Cell Proliferation; Glucose; Humans; Hypoglycemic Agents; Insulin; Molecular Structure; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Rosiglitazone

2020
In Silico Modeling of Spirolides and Gymnodimines: Determination of
    Toxins, 2020, 10-29, Volume: 12, Issue:11

    Topics: 4-Butyrolactone; Carbon; Heterocyclic Compounds, 3-Ring; Hydrocarbons, Cyclic; Imines; Molecular Dynamics Simulation; Spiro Compounds

2020
MmfL catalyses formation of a phosphorylated butenolide intermediate in methylenomycin furan biosynthesis.
    Chemical communications (Cambridge, England), 2020, Nov-19, Volume: 56, Issue:92

    Topics: 4-Butyrolactone; Anti-Bacterial Agents; Bacterial Proteins; Biosynthetic Pathways; Catalysis; Escherichia coli; Furans; Gene Expression Regulation, Bacterial; Peptides; Phosphorylation; Streptomyces; Structure-Activity Relationship

2020
Desmethyl butenolides are optimal ligands for karrikin receptor proteins.
    The New phytologist, 2021, Volume: 230, Issue:3

    Topics: 4-Butyrolactone; Arabidopsis Proteins; Hydrolases; Lactones; Ligands; Plant Growth Regulators

2021
Bioactive aromatic butenolides from a mangrove sediment originated fungal species, Aspergillus terreus SCAU011.
    Fitoterapia, 2021, Volume: 150

    Topics: 4-Butyrolactone; Anti-Bacterial Agents; Antioxidants; Aspergillus; China; Cyclooxygenase 2 Inhibitors; Geologic Sediments; Glycoside Hydrolase Inhibitors; Molecular Structure; Rhizophoraceae; Staphylococcus aureus

2021
Antiviral Activity of 3D, a Butene Lactone Derivative Against Influenza A Virus In Vitro and In Vivo.
    Viruses, 2021, 02-11, Volume: 13, Issue:2

    Topics: 4-Butyrolactone; A549 Cells; Animals; Antiviral Agents; Cell Line; Cytokines; Dogs; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza, Human; Lactones; Madin Darby Canine Kidney Cells; Mice; Mice, Inbred BALB C

2021
New immunosuppressive secondary metabolites from the endophytic fungus Aspergillus sp.
    Fitoterapia, 2021, Volume: 151

    Topics: 4-Butyrolactone; Animals; Aspergillus; Benzopyrans; Biological Products; Cells, Cultured; China; Endophytes; Immunosuppressive Agents; Male; Mice; Mice, Inbred BALB C; Molecular Structure; Secondary Metabolism; T-Lymphocytes; Tripterygium

2021
A toxicogenomics approach reveals characteristics supporting the honey bee (Apis mellifera L.) safety profile of the butenolide insecticide flupyradifurone.
    Ecotoxicology and environmental safety, 2021, Jul-01, Volume: 217

    Topics: 4-Butyrolactone; Animals; Bees; Cytochrome P-450 Enzyme System; Fungicides, Industrial; Imidazoles; Insecticides; Neonicotinoids; Pyridines; Toxicogenetics; Triazoles

2021
Utility of novel 2-furanones in synthesis of other heterocyclic compounds having anti-inflammatory activity with dual COX2/LOX inhibition.
    Journal of enzyme inhibition and medicinal chemistry, 2021, Volume: 36, Issue:1

    Topics: 4-Butyrolactone; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Heterocyclic Compounds; Humans; Lipoxygenase Inhibitors; Molecular Structure; Structure-Activity Relationship; Tumor Necrosis Factor-alpha

2021
Utility of Certain 2-Furanone Derivatives for Synthesis of Different Heterocyclic Compounds and Testing their Anti-Cancer Activity.
    Medicinal chemistry (Shariqah (United Arab Emirates)), 2022, Volume: 18, Issue:3

    Topics: 4-Butyrolactone; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Heterocyclic Compounds; Molecular Structure; Structure-Activity Relationship

2022
Copper-Catalyzed Phosphorylation of 2,3-Allenoic Acids and Phosphine Oxide: Access to Phosphorylated Butenolides.
    The Journal of organic chemistry, 2021, 07-16, Volume: 86, Issue:14

    Topics: 4-Butyrolactone; Catalysis; Copper; Oxides; Phosphines; Phosphorylation

2021
An Approach for the Generation of γ-Propenylidene-γ-butenolides and Application to the Total Synthesis of Rubrolides.
    Organic letters, 2021, 08-06, Volume: 23, Issue:15

    Topics: 4-Butyrolactone; Alkynes; Biological Products; Furans; Molecular Structure; Propanols

2021
Chiral Bifunctional Phosphine Ligand-Enabled Cooperative Cu Catalysis: Formation of Chiral α,β-Butenolides via Highly Enantioselective γ-Protonation.
    Journal of the American Chemical Society, 2021, 07-28, Volume: 143, Issue:29

    Topics: 4-Butyrolactone; Coordination Complexes; Copper; Ligands; Molecular Structure; Phosphines; Protons; Stereoisomerism

2021
Synthesis, antibacterial activity and mechanism of new butenolides derivatives containing an amide moiety.
    Pesticide biochemistry and physiology, 2021, Volume: 178

    Topics: 4-Butyrolactone; Amides; Anti-Bacterial Agents; Microbial Sensitivity Tests; Oryza; Oxadiazoles; Plant Diseases; Xanthomonas

2021
Construction of Enantioenriched γ,γ-Disubstituted Butenolides Enabled by Chiral Amine and Lewis Acid Cascade Cocatalysis.
    Organic letters, 2021, 10-01, Volume: 23, Issue:19

    Topics: 4-Butyrolactone; Aldehydes; Amines; Catalysis; Cyclization; Molecular Structure; Pyrrolidines; Stereoisomerism

2021
Synthetic Analogue of Butenolide as an Antifouling Agent.
    Marine drugs, 2021, Aug-25, Volume: 19, Issue:9

    Topics: 4-Butyrolactone; Animals; Biofouling; Carbamates; Larva; Paint; Polychaeta; Polyesters; Polyurethanes; Thoracica

2021
Structures and absolute configurations of butenolide derivatives from the isopod-associated fungus Pidoplitchkoviella terricola.
    Phytochemistry, 2022, Volume: 193

    Topics: 4-Butyrolactone; Animals; Ascomycota; Isopoda; Molecular Structure

2022
Ligand-controlled divergent dehydrogenative reactions of carboxylic acids via C-H activation.
    Science (New York, N.Y.), 2021, Dec-03, Volume: 374, Issue:6572

    Topics: 4-Butyrolactone; Carbon; Carboxylic Acids; Catalysis; Chemical Phenomena; Chemistry Techniques, Synthetic; Hydrogen; Hydrogen Bonding; Ligands; Molecular Structure; Oxidation-Reduction; Oxygen; Palladium; Pyridines; Pyridones

2021
New Deoxyenhygrolides from
    Marine drugs, 2022, Jan-14, Volume: 20, Issue:1

    Topics: 4-Butyrolactone; Animals; Aquatic Organisms; Myxococcales

2022
Palladium-Catalyzed Enantioselective γ-Arylation of β,γ-Unsaturated Butenolides.
    Angewandte Chemie (International ed. in English), 2022, 06-07, Volume: 61, Issue:23

    Topics: 4-Butyrolactone; Catalysis; Palladium; Stereoisomerism

2022
New Metabolites from the Marine Sponge
    Marine drugs, 2022, Mar-02, Volume: 20, Issue:3

    Topics: 4-Butyrolactone; Animals; Bays; Biological Products; Comoros; Magnetic Resonance Spectroscopy; Molecular Structure; Phospholipids; Piperazines; Porifera

2022
A butenolide signaling system synergized with biosynthetic gene modules led to effective activation and enhancement of silent oviedomycin production in Streptomyces.
    Metabolic engineering, 2022, Volume: 72

    Topics: 4-Butyrolactone; Aminoglycosides; Biological Products; Ethers, Cyclic; Gene Regulatory Networks; Multigene Family; Streptomyces

2022
Tongalides, Halogenated Butenolides from an Antarctic
    Journal of natural products, 2022, 07-22, Volume: 85, Issue:7

    Topics: 4-Butyrolactone; Antarctic Regions; Anti-Bacterial Agents; Molecular Structure; Plant Extracts

2022
Acylated sucroses and butenolide analog from the leaves of Tripterygium wilfordii Hook. f. and their potential anti-tyrosinase effects.
    Fitoterapia, 2022, Volume: 161

    Topics: 4-Butyrolactone; Molecular Docking Simulation; Molecular Structure; Monophenol Monooxygenase; Tripterygium

2022
Synthesis of carbohydrate analogues of the THF-acetogenin 4-deoxyannomontacin and their cytotoxicity against human prostate cancer cell lines.
    Carbohydrate research, 2022, Volume: 521

    Topics: 4-Butyrolactone; Acetogenins; Alkenes; Antineoplastic Agents; Carbohydrates; Cell Line, Tumor; Humans; Male; Mannose; Prostatic Neoplasms; Thiophenes; Trichothecenes

2022
Enantioselective Synthesis of Fused Butyrolactones via Organocatalytic Formal [2 + 2 + 2] Annulation of γ-Butenolides, Methylene Indolinones, and Nitroolefins.
    Organic letters, 2022, Oct-07, Volume: 24, Issue:39

    Topics: 4-Butyrolactone; Oxindoles; Stereoisomerism; Thiourea

2022
Effect of histidine covalent modification on strigolactone receptor activation and selectivity.
    Biophysical journal, 2023, 04-04, Volume: 122, Issue:7

    Topics: 4-Butyrolactone; Arabidopsis; Carrier Proteins; Histidine; Lactones

2023
Two New Pairs of Enantiomeric Butenolides from the Marine Sponge Suberties sp.
    Chemistry & biodiversity, 2023, Volume: 20, Issue:8

    Topics: 4-Butyrolactone; Animals; Anti-Bacterial Agents; Circular Dichroism; Molecular Structure; Porifera

2023