butamben has been researched along with benzocaine in 52 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 11 (21.15) | 18.7374 |
1990's | 15 (28.85) | 18.2507 |
2000's | 14 (26.92) | 29.6817 |
2010's | 9 (17.31) | 24.3611 |
2020's | 3 (5.77) | 2.80 |
Authors | Studies |
---|---|
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
Abellán Guillén, A; Cordeiro, MN; Garrido Escudero, A; Morales Helguera, A; Pérez-Garrido, A | 1 |
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
Arita, T; Juni, K; Nakano, M | 1 |
Ackerman, EW; Bal, F; Boon, WF; Crommelin, MA; Grouls, RJ; Hoefsloot, F; Korsten, HH; Ribot, JG; Slooff, JL; van Zundert, AA | 1 |
Bruynzeel, DP; van Ketel, WG | 1 |
Faulder, GC; Mazumdar, B; Tomlinson, AA | 1 |
Ackerman, EW; Grouls, RJ; Korsten, HH; Machielsen, EJ | 1 |
Ackerman, EW; Grouls, RJ; Gruys, E; Hellebrekers, LJ; Korsten, HH; van Herpen, H; van Zundert, AA | 1 |
Glickman, R; Greenfield, W; Hittelman, EL | 1 |
Amano, Y; Kakinuma, T; Kobayashi, K; Koike, S; Nikura, M; Sagiya, T; Saito, Y; Suda, M; Yamaguchi, N; Yarita, M | 1 |
Lue, RY; Zatz, JL | 1 |
Adriani, J; Beuttler, WA; Brihmadesam, L; Naraghi, M | 1 |
McEvoy, GK; Olson, ML | 1 |
Flynn, GL; Lalor, CB; Weiner, N | 1 |
Grouls, RJ; Korsten, HH; Van den Berg, RJ; Van Soest, PF; Wang, Z | 1 |
Armstrong, DG; Kanat, IO | 1 |
Kragh-Hansen, U; Maruyama, T; Otagiri, M; Yamasaki, K | 1 |
Ackerman, EW; Breimer, DD; Grouls, RJ; Hellebrekers, LJ; Korsten, HH; Machielsen, E | 1 |
Grouls, RJ; Korsten, HH; Van den Berg, RJ; Wang, Z | 1 |
Breimer, DD; Grouls, RJ; Hellebrekers, LJ; Korsten, HH; Meert, TF | 1 |
Ackerman, EW; Breimer, DD; Grouls, RJ; Hellebrekers, LJ; Korsten, HH | 1 |
Bommireddi, A; Ginsburg, E; Li, LC; Robinson, D; Stephens, D | 1 |
Cousins, MJ; Mitchell, VA; White, DM | 1 |
Bommireddi, AR; Buko, AM; Ginsburg, EJ; Li, LC; Robinson, DH; Stephens, DA; West, PR | 1 |
Fujiwara, Y; Kuroda, Y; Nakagawa, T; Nasu, H | 1 |
Ackerman, E; Breimer, D; Grouls, R; Hellebrekers, L; Korsten, E; van Zundert, A | 1 |
Harris, JE; Ivankovich, AD; Lubenow, TR; Nath, HA; Shulman, M | 1 |
Ivankovich, AD; Kerns, JM; McCarthy, RJ; Nath, HA; Shulman, M | 1 |
Blumberg, B; Cao, J; Grün, F; Hemmati, D; Tabb, MM; Venkatesan, RN; Zhou, C | 1 |
Beekwilder, JP; O'Leary, ME; van den Berg, RJ; van den Broek, LP; van Kempen, GT; Ypey, DL | 1 |
BAUMANN, J; PICARD-LEROY, G | 1 |
Cristea, M; Kolesnikov, YA; Pasternak, GW | 1 |
RONCHESE, F | 1 |
Beekwilder, JP; van den Berg, RJ; van Kempen, GTH; Winkelman, DLB; Ypey, DL | 1 |
Beck, CL; O'Leary, ME; Winkelman, DL; Ypey, DL | 1 |
Schmidt, AC | 1 |
Beekwilder, JP; van den Berg, RJ; van Kempen, GT; Ypey, DL | 1 |
Beekwilder, JP; Rampaart, LJ; van den Berg, RJ; van Kempen, GT; Ypey, DL | 1 |
LADEN, EL; RUBIN, L | 2 |
Ghelardini, C; González-Rodríguez, ML; Maestrelli, F; Mura, P; Rabasco, AM | 1 |
Han, YM; Kim, HJ; Kim, SH; Kwon, BM; Park, M | 1 |
Bang, S; Heo, TH; Hwang, SW; Yang, TJ; Yoo, S | 1 |
Casadei, BR; Cereda, CM; da Silva, CM; de Araujo, DR; de Paula, E; Domingues, CC; Franz-Montan, M; Tofoli, GR | 1 |
Chahine, M; de Groat, WC; O'Leary, ME; Poulin, H; Sculptoreanu, A; Thériault, O | 1 |
Berka, K; DeVane, RH; Murch, BP; Otyepka, M; Paloncýová, M | 1 |
Alkschbirs, MI; Cereda, CM; de Araujo, DR; de Brito Junior, RB; de Paula, E; Franz-Montan, M; Guilherme, VA; Tofoli, GR | 1 |
Krishna, GR; Rasmuson, ÅC; Svärd, M; Valavi, M; Zeng, L | 1 |
Breitkreitz, MC; Carvalho Dos Santos, A; Carvalho, NS; de Moura, LD; de Paula, E; Freitas de Lima, F; Geronimo, G; Lemes, JBP; Malange, KF; Parada, CA; Rodrigues da Silva, GH | 1 |
Beaudry, P; Bizat, N; Brandel, JP; Gougerot, A; Haïk, S; Laoues, S; Laplanche, JL; Levavasseur, E; Normant, S; Parrales, V; Privat, N; Ravassard, P; Roussel, J | 1 |
Breitkreitz, MC; de Paula, E; Mitsutake, H; Rodrigues da Silva, GH | 1 |
3 trial(s) available for butamben and benzocaine
Article | Year |
---|---|
[Clinical evaluation of new toothache drug "LTA"].
Topics: Adult; Anesthetics, Local; Benzocaine; Child; Clinical Trials as Topic; Dibucaine; Ethanolamines; Eugenol; Female; Humans; Male; Middle Aged; Toothache | 1986 |
Analgesic efficacy of topical butamben picrate.
Topics: Adolescent; Adult; Aged; Anesthetics, Local; Benzocaine; Child; Female; Humans; Male; Middle Aged; Pain, Postoperative | 1995 |
Comparison of epidural butamben to celiac plexus neurolytic block for the treatment of the pain of pancreatic cancer.
Topics: Adult; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthetics, Local; Benzocaine; Celiac Plexus; Female; Humans; Male; Middle Aged; Nerve Block; Pain; Pancreatic Neoplasms; Treatment Outcome | 2000 |
49 other study(ies) available for butamben and benzocaine
Article | Year |
---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Convenient QSAR model for predicting the complexation of structurally diverse compounds with beta-cyclodextrins.
Topics: beta-Cyclodextrins; Hydrophobic and Hydrophilic Interactions; Organic Chemicals; Quantitative Structure-Activity Relationship | 2009 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Controlled drug permeation. II. Comparative permeability and stability of butamben and benzocaine.
Topics: Benzocaine; Drug Stability; Membranes, Artificial; Permeability | 1977 |
Long-lasting epidural sensory blockade by n-butyl-p-aminobenzoate in the terminally ill intractable cancer pain patient.
Topics: Adult; Aged; Analgesia, Epidural; Benzocaine; Female; Humans; Male; Middle Aged; Neoplasms; Nerve Block; Pain, Intractable; Spinal Cord; Spinal Nerve Roots | 1991 |
A 'forgotten' topical anaesthetic sensitizer: butyl aminobenzoate.
Topics: Anesthetics, Local; Benzocaine; Drug Eruptions; Eczema; Female; Humans; Male; Middle Aged | 1991 |
Preliminary study to assay plasma amethocaine concentrations after topical application of a new local anaesthetic cream containing amethocaine.
Topics: Administration, Cutaneous; Adult; Anesthesia, Local; Anesthetics, Local; Benzocaine; Chromatography, High Pressure Liquid; Humans; Skin Absorption; Tetracaine; Time Factors | 1991 |
Butyl-p-aminobenzoate. Preparation, characterization and quality control of a suspension injection for epidural analgesia.
Topics: Analgesics; Benzocaine; Drug Stability; Hydrogen-Ion Concentration; Injections, Epidural; Particle Size; Polyethylene Glycols; Polysorbates; Quality Control; Suspensions | 1991 |
Long-lasting epidural sensory blockade by n-butyl p-aminobenzoate in the dog: neurotoxic or local anesthetic effect?
Topics: Analgesia, Epidural; Anesthetics, Local; Animals; Benzocaine; Dogs; Female; Injections, Epidural; Male; Nervous System; Sensation; Time Factors | 1990 |
Evaluation of anesthetic agents on human mucous membrane: an illustration of experimental protocol using computers.
Topics: Adult; Anesthetics, Local; Benzocaine; Computers; Female; Humans; Male; Mouth Mucosa; Random Allocation; Tetracaine; Time Factors | 1986 |
Flocculation of suspensions containing nonionic surfactants by sorbitol.
Topics: Benzocaine; Flocculation; Polysorbates; Salicylamides; Sorbitol; Sulfamerazine; Surface-Active Agents; Suspensions; Temperature | 1987 |
Topical anesthetics: use and misuse.
Topics: Aerosols; Anesthetics, Local; Benzocaine; Humans; Lidocaine; Mouthwashes; Ointments; Powders; Propiophenones; Propoxycaine; Suppositories; Tablets; Tetracaine; Tripelennamine | 1985 |
Methemoglobinemia induced by local anesthetics.
Topics: 4-Aminobenzoic Acid; Adult; Aminobenzoates; Anesthetics, Local; Benzocaine; Cyanosis; Humans; Intubation, Intratracheal; Male; Methemoglobinemia; Tetracaine | 1981 |
Formulation factors affecting release of drug from topical vehicles. II. Effect of solubility on in vitro delivery of a series of n-alkyl p-aminobenzoates.
Topics: 4-Aminobenzoic Acid; Administration, Topical; Benzocaine; Chemical Phenomena; Chemistry, Physical; Diffusion; Drug Compounding; Drug Delivery Systems; Emulsions; Micelles; para-Aminobenzoates; Pharmaceutical Vehicles; Solubility; Spectrophotometry, Ultraviolet; Thermodynamics | 1995 |
The local anesthetic n-butyl-p-aminobenzoate selectively affects inactivation of fast sodium currents in cultured rat sensory neurons.
Topics: Action Potentials; Anesthetics, Local; Animals; Benzocaine; Cells, Cultured; Ganglia, Spinal; Rats; Sodium Channels; Tetrodotoxin | 1995 |
Characterization of site I on human serum albumin: concept about the structure of a drug binding site.
Topics: Acenocoumarol; Anticoagulants; Asparagine; Benzocaine; Binding Sites; Binding, Competitive; Dansyl Compounds; Fluorescent Dyes; Humans; Iodipamide; Phenylbutazone; Serum Albumin; Warfarin | 1996 |
Capillary gas chromatographic method for the determination of n-butyl-p-aminobenzoate and lidocaine in plasma samples.
Topics: Anesthetics, Local; Animals; Benzocaine; Blood Specimen Collection; Calibration; Cholinesterase Inhibitors; Chromatography, Gas; Dogs; Drug Stability; Humans; Injections, Epidural; Isoflurophate; Lidocaine; Reproducibility of Results; Sensitivity and Specificity | 1995 |
The local anesthetic, n-butyl-p-aminobenzoate, reduces rat sensory neuron excitability by differential actions on fast and slow Na+ current components.
Topics: Action Potentials; Anesthetics, Local; Animals; Benzocaine; Ganglia, Spinal; Membrane Potentials; Neurons, Afferent; Rats; Sensitivity and Specificity; Sodium; Sodium Channels; Solutions; Tetrodotoxin | 1996 |
Epidural and intrathecal n-butyl-p-aminobenzoate solution in the rat. Comparison with bupivacaine.
Topics: Anesthesia, Epidural; Anesthetics, Local; Animals; Benzocaine; Bupivacaine; Dose-Response Relationship, Drug; Injections, Spinal; Rats; Rats, Wistar; Solutions | 1997 |
Partition coefficients (n-octanol/water) of N-butyl-p-aminobenzoate and other local anesthetics measured by reversed-phase high-performance liquid chromatography.
Topics: 1-Octanol; Anesthetics, Local; Benzocaine; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Octanols; Solubility; Water | 1997 |
Particle size determination of a flocculated suspension using a light-scattering particle size analyzer.
Topics: Benzocaine; Chemistry, Pharmaceutical; Flocculation; Humans; Light; Microscopy, Polarization; Particle Size; Scattering, Radiation; Suspensions | 1998 |
The long-term effect of epidural administration of butamben suspension on nerve injury-induced allodynia in rats.
Topics: Analgesia, Epidural; Anesthetics, Local; Animals; Benzocaine; Disease Models, Animal; Locomotion; Longitudinal Studies; Male; Motor Activity; Neuralgia; Nociceptors; Pain Threshold; Pharmaceutical Vehicles; Physical Stimulation; Rats; Rats, Wistar; Sciatic Nerve; Time Factors | 1999 |
Identification of a yellow impurity in aged samples of aqueous butamben suspension: evidence for the oxidative degradation of poly(ethylene glycol).
Topics: Benzocaine; Chromatography, High Pressure Liquid; Magnetic Resonance Spectroscopy; Oxidation-Reduction; Polyethylene Glycols; Spectrometry, Mass, Fast Atom Bombardment; Water | 2000 |
Orientations and locations of local anesthetics benzocaine and butamben in phospholipid membranes as studied by 2H NMR spectroscopy.
Topics: Anesthetics, Local; Benzocaine; Cholesterol; Deuterium; Magnetic Resonance Spectroscopy; Membranes, Artificial; Models, Biological; Molecular Conformation; Palmitic Acid; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Phospholipids; Structure-Activity Relationship | 2000 |
Diffusion of n-butyl-p-aminobenzoate (BAB), lidocaine and bupivacaine through the human dura-arachnoid mater in vitro.
Topics: Anesthetics, Local; Arachnoid; Benzocaine; Bupivacaine; Diffusion; Dura Mater; Humans; In Vitro Techniques; Kinetics; Lidocaine; Spinal Cord | 2000 |
The antinociceptive and histologic effect of sciatic nerve blocks with 5% butamben suspension in rats.
Topics: Anesthetics, Local; Animals; Benzocaine; Male; Nerve Block; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Suspensions; Time Factors | 2002 |
Benzoate X receptors alpha and beta are pharmacologically distinct and do not function as xenobiotic receptors.
Topics: Animals; Benzoates; Benzocaine; Chlorpyrifos; COS Cells; DNA, Complementary; Dose-Response Relationship, Drug; Female; Intestinal Mucosa; Ligands; Liver; Male; Parabens; Protein Binding; Protein Structure, Tertiary; Receptors, Cytoplasmic and Nuclear; RNA; Tissue Distribution; Transfection; Trifluralin; Two-Hybrid System Techniques; Xenobiotics; Xenopus; Xenopus Proteins | 2002 |
Kv1.1 channels of dorsal root ganglion neurons are inhibited by n-butyl-p-aminobenzoate, a promising anesthetic for the treatment of chronic pain.
Topics: Action Potentials; Anesthetics, Local; Animals; Benzocaine; Cells, Cultured; Chronic Disease; Ganglia, Spinal; Humans; In Vitro Techniques; Kv1.1 Potassium Channel; Mice; Neurons; Pain; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated | 2003 |
[Danger in the use of procaine with butyl aminobenzoate in thoracic surgery].
Topics: Aminobenzoates; Analgesia; Anesthesia; Anesthesia and Analgesia; Benzocaine; Pain; Pain Management; Procaine; Thoracic Surgery; Thorax | 1954 |
Analgesic synergy between topical morphine and butamben in mice.
Topics: Administration, Topical; Analgesics, Opioid; Anesthetics, Local; Animals; Benzocaine; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Lidocaine; Male; Mice; Mice, Inbred ICR; Morphine; Pain Measurement; Reaction Time | 2003 |
Dermatitis venenata from butesin picrate ointment.
Topics: Benzocaine; Burns; Dermatitis, Contact; Drug Eruptions; Picrates | 1951 |
The block of total and N-type calcium conductance in mouse sensory neurons by the local anesthetic n-butyl-p-aminobenzoate.
Topics: Action Potentials; Algorithms; Anesthetics, Local; Animals; Animals, Newborn; Barium; Benzocaine; Calcium Channel Blockers; Calcium Channels, N-Type; Ganglia, Spinal; Membrane Potentials; Mice; Neurons, Afferent; Patch-Clamp Techniques | 2005 |
Inhibition of the A-type K+ channels of dorsal root ganglion neurons by the long-duration anesthetic butamben.
Topics: Amino Acid Sequence; Anesthetics, Local; Animals; Benzocaine; Ganglia, Spinal; Ion Channel Gating; Molecular Sequence Data; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Rats; Shal Potassium Channels; Tetraethylammonium | 2005 |
Structural characteristics and crystal polymorphism of three local anaesthetic bases crystal polymorphism of local anaesthetic drugs: part VII.
Topics: Anesthetics, Local; Benzocaine; Calorimetry, Differential Scanning; Crystallization; Drug Stability; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Thermodynamics; X-Ray Diffraction | 2005 |
The local anesthetic butamben inhibits and accelerates low-voltage activated T-type currents in small sensory neurons.
Topics: Action Potentials; Anesthetics, Local; Animals; Animals, Newborn; Benzocaine; Calcium Channel Blockers; Calcium Channels, T-Type; Cells, Cultured; Dose-Response Relationship, Drug; Mice; Neurons, Afferent | 2006 |
The local anesthetic butamben inhibits total and L-type barium currents in PC12 cells.
Topics: Analgesics; Anesthetics, Local; Animals; Barium; Benzocaine; Calcium Channel Blockers; Calcium Channels, L-Type; Neurons; Nifedipine; Patch-Clamp Techniques; PC12 Cells; Rats | 2008 |
Epidermal sensitization to butesin, an experimental study on the range of specificity.
Topics: Anesthesia, Local; Benzocaine; Epidermis; Sensitivity and Specificity | 1948 |
Specificity of eczematous hypersensitivity to p-aminobenzoic acid butyl ester (butesin).
Topics: 4-Aminobenzoic Acid; Acids; Benzocaine; Eczema; Esters; Hypersensitivity | 1947 |
New "drug-in cyclodextrin-in deformable liposomes" formulations to improve the therapeutic efficacy of local anaesthetics.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Amines; Anesthetics, Local; Animals; Benzocaine; beta-Cyclodextrins; Chemistry, Pharmaceutical; Cholesterol; Conjunctiva; Dialysis; Drug Carriers; Drug Compounding; Kinetics; Light; Liposomes; Male; Microscopy, Confocal; Particle Size; Permeability; Phosphatidylcholines; Rabbits; Reflex; Scattering, Radiation; Sensory Thresholds; Solubility; Surface Properties; Surface-Active Agents; Technology, Pharmaceutical | 2010 |
Butamben derivatives enhance BMP-2-stimulated commitment of C2C12 cells into osteoblasts with induction of voltage-gated potassium channel expression.
Topics: 4-Aminobenzoic Acid; Alkaline Phosphatase; Animals; Benzocaine; Bone Morphogenetic Protein 2; Cell Differentiation; Cell Line; Gene Expression Regulation; Mice; Osteoblasts; para-Aminobenzoates; Potassium Channels, Voltage-Gated; RNA, Messenger; Signal Transduction | 2011 |
Inhibition of sensory neuronal TRPs contributes to anti-nociception by butamben.
Topics: Anesthetics, Local; Animals; Benzocaine; HEK293 Cells; Humans; Pain; Patch-Clamp Techniques; Sensory Receptor Cells; TRPC Cation Channels; TRPV Cation Channels | 2012 |
Transdermal delivery of butamben using elastic and conventional liposomes.
Topics: Administration, Cutaneous; Anesthetics, Local; Animals; Benzocaine; Drug Compounding; Elasticity; Fluorescence Polarization; Gels; Liposomes; Particle Size; Reproducibility of Results; Skin Absorption; Swine | 2013 |
Modulation of peripheral Na(+) channels and neuronal firing by n-butyl-p-aminobenzoate.
Topics: Action Potentials; Anesthetics, Local; Animals; Benzocaine; Dose-Response Relationship, Drug; Ganglia, Spinal; HEK293 Cells; Humans; Male; NAV1.6 Voltage-Gated Sodium Channel; NAV1.7 Voltage-Gated Sodium Channel; NAV1.8 Voltage-Gated Sodium Channel; Neurons; Rats, Sprague-Dawley; Sodium Channel Blockers; Time Factors; Transfection; Voltage-Gated Sodium Channels | 2014 |
Rationalization of reduced penetration of drugs through ceramide gel phase membrane.
Topics: Anesthetics, Local; Benzocaine; Ceramides; Lipid Bilayers; Models, Chemical; Phosphatidylcholines | 2014 |
Liposomal butamben gel formulations: toxicity assays and topical anesthesia in an animal model.
Topics: 3T3 Cells; Administration, Topical; Anesthesia, Local; Animals; Benzocaine; Cell Survival; Cells, Cultured; Disease Models, Animal; Gels; Injections, Intraperitoneal; Liposomes; Mice; Mice, Inbred BALB C; Rats; Rats, Wistar | 2017 |
Solid and Solution State Thermodynamics of Polymorphs of Butamben (Butyl 4-Aminobenzoate) in Pure Organic Solvents.
Topics: 2-Propanol; Benzocaine; Calorimetry, Differential Scanning; Crystallization; Hot Temperature; Methanol; Solubility; Solvents; Temperature; Thermodynamics; Transition Temperature; X-Ray Diffraction | 2019 |
Lipid nanoparticles loaded with butamben and designed to improve anesthesia at inflamed tissues.
Topics: Anesthesia; Animals; Benzocaine; Drug Carriers; Lipids; Nanoparticles; Nanostructures; Particle Size; Rats | 2021 |
An in vivo Caenorhabditis elegans model for therapeutic research in human prion diseases.
Topics: Animals; Animals, Genetically Modified; Benzocaine; Brain; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Disease Models, Animal; Humans; Naloxone; Piroxicam; Prion Diseases; Prion Proteins; Protein Aggregation, Pathological; Tubulin | 2021 |
When it is too much: Identifying butamben excess on the surface of pharmaceutical preformulation samples by Raman mapping.
Topics: Benzocaine; Excipients; Lipids; Pharmaceutical Preparations | 2023 |