busulfan and azathioprine

busulfan has been researched along with azathioprine in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199019 (57.58)18.7374
1990's0 (0.00)18.2507
2000's4 (12.12)29.6817
2010's10 (30.30)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Rassner, G1
Matthay, RA; Putman, CE; Sostman, HD1
Schein, PS; Winokur, SH1
Hardt, F1
Almeyda, J; Levantine, A1
Shepard, TH1
Engelmann, C; Konrad, H; Nowotny, P; Schulz, K1
Chan, WC; Dukes, M; Willoughby, DA1
Abdulsalam, M; Iskandar, W; Markum, AH; Muslichan, S1
Tuchmann-Duplessis, H1
Cohen, ML; Weiss, EB1
Shapovalova, SP1
Stacher, A1
Rowland, LP1
Mamou, H1
Brambilla, G; Caraceni, CE; Cavanna, M; Parodi, S1
Revell, PA; Soretire, EA1
Collis, CH1
Doskocz, W; Giełdanowski, J1
Andreani, M; Gaziev, J; Lucarelli, G; Polchi, P; Sodani, P1
Ahmad, J; BuchBarker, D; Habib, S; Nalesnik, MA; Shakil, AO1

Reviews

4 review(s) available for busulfan and azathioprine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Immunosuppressive and cytotoxic chemotherapy: long-term complications.
    Annals of internal medicine, 1975, Volume: 82, Issue:1

    Topics: Alkylating Agents; Antineoplastic Agents; Azathioprine; Bleomycin; Busulfan; Carcinogens; Chemical and Drug Induced Liver Injury; Daunorubicin; Doxorubicin; Female; Fetus; Folic Acid Antagonists; Follow-Up Studies; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Infertility, Female; Infertility, Male; Liver; Lung Diseases; Male; Mercaptopurine; Methotrexate; Myocarditis; Neoplasms; Ovary; Pregnancy; Procarbazine; Streptozocin; Testis; Urologic Diseases

1975
Drug reactions. XXIV. Cutaneous reactions to cytostatic agents.
    The British journal of dermatology, 1974, Volume: 90, Issue:2

    Topics: Alopecia; Aminopterin; Antineoplastic Agents; Asparaginase; Azathioprine; Bleomycin; Busulfan; Chlorambucil; Cyclophosphamide; Dactinomycin; Drug Eruptions; Erythema; Fluorouracil; Gynecomastia; Humans; Hydroxyurea; Methotrexate; Photosensitivity Disorders; Pigmentation Disorders; Radiation Injuries; Stomatitis; Vinblastine

1974
Lung damage from cytotoxic drugs.
    Cancer chemotherapy and pharmacology, 1980, Volume: 4, Issue:1

    Topics: Antineoplastic Agents; Azathioprine; Bleomycin; Busulfan; Carmustine; Chlorambucil; Cyclophosphamide; Drug Therapy, Combination; Humans; Lung; Melphalan; Mercaptopurine; Methotrexate; Mitomycins; Oxygen Inhalation Therapy; Pneumonia; Procarbazine; Radiation Injuries

1980

Other Studies

29 other study(ies) available for busulfan and azathioprine

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
[Practical aspects of the cytostatic therapy of psoriasis].
    Zeitschrift fur Hautkrankheiten, 1976, Jun-15, Volume: 51, Issue:12

    Topics: Antineoplastic Agents; Azathioprine; Bleomycin; Busulfan; Chemical and Drug Induced Liver Injury; Humans; Methotrexate; Psoriasis; Time Factors

1976
Cytotoxic drug-induced lung disease.
    The American journal of medicine, 1977, Volume: 62, Issue:4

    Topics: Antibiotics, Antineoplastic; Azathioprine; Bleomycin; Busulfan; Cyclophosphamide; Dose-Response Relationship, Drug; Humans; Lung Diseases; Lung Neoplasms; Mercaptopurine; Methotrexate; Radiography

1977
Acceleration of casein induced amyloidosis in mice by immunosuppressive agents.
    Acta pathologica et microbiologica Scandinavica. Section A, Pathology, 1971, Volume: 79, Issue:1

    Topics: Amyloid; Amyloidosis; Animals; Azathioprine; Busulfan; Caseins; Chloramphenicol; Cortisone; Dactinomycin; Daunorubicin; DNA; Female; Fluorouracil; Immunosuppressive Agents; Liver; Male; Mercaptopurine; Methotrexate; Mice; RNA; Spleen; Vinblastine

1971
Teratogenicity from drugs--an increasing problem.
    Disease-a-month : DM, 1974

    Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Aminopterin; Amniocentesis; Animals; Anti-Bacterial Agents; Azathioprine; Azauridine; Busulfan; Chlorambucil; Colchicine; Contraceptives, Oral; Cyclophosphamide; Diethylstilbestrol; Ethanol; Female; Fetus; Genotype; Humans; Iodine Radioisotopes; Mercaptopurine; Methotrexate; Mice; Nitrogen Mustard Compounds; Phenotype; Pregnancy; Pregnancy, Animal; Prenatal Diagnosis; Radiation Genetics; Rats; Species Specificity; Thalidomide; Tranquilizing Agents

1974
[Indications for cytostatic treatment of patients with osteomyelosclerosis of osteomyelofibrosis].
    Das Deutsche Gesundheitswesen, 1972, Dec-14, Volume: 27, Issue:50

    Topics: Adult; Aged; Antineoplastic Agents; Azathioprine; Busulfan; Female; Humans; Male; Mannitol; Mercaptopurine; Middle Aged; Osteosclerosis; Primary Myelofibrosis

1972
The effect of various immunosuppressive agents on the vascular and cellular response to carvageenan in the rat.
    The Journal of pathology, 1973, Volume: 109, Issue:2

    Topics: Animals; Azathioprine; Busulfan; Carrageenan; Chlorambucil; Cyclophosphamide; Edema; Immunosuppressive Agents; Inflammation; Leukocyte Count; Male; Mercaptopurine; Methotrexate; Rats; Time Factors

1973
Immunosuppressive agents in the treatment of chronic idiopathic thrombocytopenic purpura.
    Paediatrica Indonesiana, 1973, Volume: 13, Issue:3

    Topics: Antibodies; Azathioprine; Blood Platelets; Busulfan; Child; Child, Preschool; Chronic Disease; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Male; Mercaptopurine; Prednisone; Purpura, Thrombocytopenic

1973
[The teratogenic risk].
    Archives d'anatomie, d'histologie et d'embryologie normales et experimentales, 1968, Volume: 51, Issue:5

    Topics: Abnormalities, Drug-Induced; Animals; Azathioprine; Busulfan; Carbutamide; Congenital Abnormalities; Cyclophosphamide; Female; Gestational Age; Humans; Lipid Metabolism; Maternal Age; Measles; Mercaptopurine; Mice; Morphogenesis; Pregnancy; Pregnancy Complications; Pregnancy Complications, Infectious; Radiation Injuries; Rats; Thalidomide; Tolbutamide

1968
Pneumocystitis carinii pneumonia: percutaneous lung biopsy and review of literature.
    Chest, 1971, Volume: 60, Issue:2

    Topics: Adolescent; Adult; Agammaglobulinemia; Amphotericin B; Anuria; Azathioprine; Biopsy; Bis-Trimethylammonium Compounds; Busulfan; Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Female; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Transplantation; Leukemia, Lymphoid; Lymphoma, Non-Hodgkin; Male; Methotrexate; Middle Aged; Mycosis Fungoides; Pneumonia, Pneumocystis; Prednisone; Transplantation, Homologous; Vincristine

1971
[Effect of rubomycin in combination with some cytostatic preparations on formation of hemagglutinins in mice].
    Antibiotiki, 1969, Volume: 14, Issue:12

    Topics: Animals; Antibiotics, Antineoplastic; Antibody Formation; Antineoplastic Agents; Azathioprine; Busulfan; Depression, Chemical; Drug Synergism; Erythrocytes; Immunosuppressive Agents; Melphalan; Mice; Olivomycins; Sheep; Skin Transplantation; Thiotepa; Time Factors

1969
[Progress in the therapy of leukoses].
    Wiener medizinische Wochenschrift (1946), 1970, Jun-13, Volume: 120, Issue:24

    Topics: Antineoplastic Agents; Azathioprine; Busulfan; Chlorambucil; Cyclophosphamide; Daunorubicin; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Mannitol; Methotrexate; Mitomycins; Triethylenemelamine; Vincristine

1970
Immunosuppressive drugs in treatment of myasthenia gravis.
    Annals of the New York Academy of Sciences, 1971, Sep-15, Volume: 183

    Topics: Adult; Autoimmune Diseases; Azathioprine; Blood Cell Count; Busulfan; Cyclophosphamide; Female; Humans; Hypersensitivity, Delayed; Immunosuppressive Agents; Male; Melphalan; Mercaptopurine; Methotrexate; Myasthenia Gravis

1971
[Current knowledge on periodic disease].
    La Presse medicale, 1970, Mar-28, Volume: 78, Issue:16

    Topics: Adrenal Cortex Hormones; Amyloidosis; Anti-Inflammatory Agents; Azathioprine; Busulfan; Ethnicity; Familial Mediterranean Fever; Female; Humans; Kidney Diseases; Male; Mercaptopurine; Norsteroids; Steroids

1970
[Preliminary studies of the evaluation of immunodepressive activity in L1210 leukemia allografts in mice].
    Bollettino della Societa italiana di biologia sperimentale, 1970, Mar-15, Volume: 46, Issue:5

    Topics: Amides; Animals; Azathioprine; Azo Compounds; Busulfan; Cyclophosphamide; Glycine; Immunosuppressive Agents; Leukemia L1210; Methotrexate; Mice; Neoplasm Transplantation; Transplantation, Homologous

1970
Kurloff cell levels in the peripheral blood of normal guinea-pigs treated with cytotoxic drugs.
    Virchows Archiv. B, Cell pathology including molecular pathology, 1980, Volume: 34, Issue:1

    Topics: Animals; Antineoplastic Agents; Azathioprine; Blood Cell Count; Blood Cells; Busulfan; Cyclophosphamide; Female; Guinea Pigs; Melphalan; Methotrexate

1980
Immunosuppressive drugs in the treatment of immunologic iridocyclitis in the rabbit.
    Archivum immunologiae et therapiae experimentalis, 1980, Volume: 28, Issue:3

    Topics: Animals; Aqueous Humor; Azathioprine; Busulfan; Drug Evaluation, Preclinical; Female; Hypersensitivity, Immediate; Immunosuppressive Agents; Male; Methotrexate; Orosomucoid; Rabbits; Sialic Acids; Thiotepa; Uveitis, Anterior

1980
Bone marrow transplantation in adults with thalassemia: Treatment and long-term follow-up.
    Annals of the New York Academy of Sciences, 2005, Volume: 1054

    Topics: Adolescent; Adult; Azathioprine; Bone Marrow Transplantation; Busulfan; Chelation Therapy; Clinical Protocols; Combined Modality Therapy; Comorbidity; Deferoxamine; Disease-Free Survival; Erythrocyte Transfusion; Erythropoietin; Female; Follow-Up Studies; Graft vs Host Disease; Granulocyte Colony-Stimulating Factor; Hematopoietic Cell Growth Factors; Hemosiderosis; Humans; Hydroxyurea; Immunosuppressive Agents; Iron Chelating Agents; Life Tables; Liver Cirrhosis; Male; Phlebotomy; Postoperative Complications; Survival Analysis; Thalassemia; Transfusion Reaction; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome; Vidarabine

2005
Alloimmune hepatitis following peripheral stem cell transplantation.
    Bone marrow transplantation, 2007, Volume: 39, Issue:9

    Topics: Adult; Anti-Inflammatory Agents; Azathioprine; Busulfan; Cyclophosphamide; Female; Graft vs Host Disease; Hepatitis, Autoimmune; Humans; Immunosuppressive Agents; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Myeloablative Agonists; Peripheral Blood Stem Cell Transplantation; Prednisone; Transplantation Conditioning; Transplantation, Homologous

2007