bupropion and selegiline

bupropion has been researched along with selegiline in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.69)18.7374
1990's1 (7.69)18.2507
2000's5 (38.46)29.6817
2010's6 (46.15)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Ahman, M; Holmén, AG; Wan, H1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Cole, JO1
Alexander, B; Ritter, JL1
Kim, M; Myung, SW; Yoon, SH1
Csoka, AB; Shipko, S1
Hollenberg, PF; Kenaan, C; Sridar, C1
Baqi, Y; Correa, M; Khan, B; Lee, CA; Makriyannis, A; Müller, CE; Nowak, V; Nunes, EJ; Pandit, S; Randall, PA; Salamone, JD; Shah, P; Vemuri, VK; Yohn, SE1
Bhyrapuneni, G; Manoharan, A; Mohammed, AR; Nirogi, R; Palacharla, RC; Ponnamaneni, RK1

Reviews

2 review(s) available for bupropion and selegiline

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Retrospective study of selegiline-antidepressant drug interactions and a review of the literature.
    Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, 1997, Volume: 9, Issue:1

    Topics: Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Antiparkinson Agents; Bupropion; Comorbidity; Depression; Drug Interactions; Humans; Monoamine Oxidase Inhibitors; Parkinson Disease; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; Selegiline

1997

Trials

1 trial(s) available for bupropion and selegiline

ArticleYear
Where are those new antidepressants we were promised?
    Archives of general psychiatry, 1988, Volume: 45, Issue:2

    Topics: Antidepressive Agents; Bupropion; Clinical Trials as Topic; Clomipramine; Depressive Disorder; Humans; Legislation, Drug; Mianserin; Nomifensine; Propiophenones; Selegiline; United States; United States Food and Drug Administration

1988

Other Studies

10 other study(ies) available for bupropion and selegiline

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Analysis of benzene ethylamine derivatives in urine using the programmable dynamic liquid-phase microextraction (LPME) device.
    The Analyst, 2003, Volume: 128, Issue:12

    Topics: Benzene Derivatives; Bupropion; Electronic Data Processing; Ephedrine; Ethylamines; Humans; Mephentermine; Methamphetamine; Microchemistry; Reproducibility of Results; Selegiline; Sensitivity and Specificity; Substance Abuse Detection

2003
Persistent sexual side effects after SSRI discontinuation.
    Psychotherapy and psychosomatics, 2006, Volume: 75, Issue:3

    Topics: Adult; Androgens; Anxiety; Bupropion; Cabergoline; Citalopram; Depressive Disorder; Dopamine Agonists; Dopamine Uptake Inhibitors; Ergolines; Female; Fluoxetine; Humans; Male; Monoamine Oxidase Inhibitors; Piperazines; Plants, Medicinal; Purines; Selective Serotonin Reuptake Inhibitors; Selegiline; Sertraline; Sexual Dysfunctions, Psychological; Sildenafil Citrate; Sleep Initiation and Maintenance Disorders; Sulfones; Testosterone; Time Factors; Treatment Outcome; Vasodilator Agents

2006
Inhibition of bupropion metabolism by selegiline: mechanism-based inactivation of human CYP2B6 and characterization of glutathione and peptide adducts.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Amino Acid Sequence; Antidepressive Agents, Second-Generation; Antiparkinson Agents; Aryl Hydrocarbon Hydroxylases; Bupropion; Chromatography, Liquid; Cytochrome P-450 CYP2B6; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Escherichia coli; Glutathione; Heme; Humans; Hydroxylation; Molecular Sequence Data; NADP; Oxidoreductases, N-Demethylating; Peptides; Selegiline; Tandem Mass Spectrometry

2012
The VMAT-2 inhibitor tetrabenazine affects effort-related decision making in a progressive ratio/chow feeding choice task: reversal with antidepressant drugs.
    PloS one, 2014, Volume: 9, Issue:6

    Topics: Animals; Antidepressive Agents; Benzazepines; Benzophenones; Bupropion; Cannabinoid Receptor Antagonists; Choice Behavior; Depression; Dopamine Antagonists; Drug Evaluation, Preclinical; Feeding Behavior; Male; Nitrophenols; Pyrazoles; Rats, Sprague-Dawley; Salicylamides; Selegiline; Tetrabenazine; Tolcapone; Vesicular Monoamine Transport Proteins; Xanthines

2014
Evaluation of metabolism dependent inhibition of CYP2B6 mediated bupropion hydroxylation in human liver microsomes by monoamine oxidase inhibitors and prediction of potential as perpetrators of drug interaction.
    Chemico-biological interactions, 2015, Mar-25, Volume: 230

    Topics: Bupropion; Clorgyline; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2B6 Inhibitors; Drug Interactions; Glutathione; Humans; Hydroxylation; Inhibitory Concentration 50; Kinesics; Microsomes, Liver; Monoamine Oxidase Inhibitors; Pargyline; Phenelzine; Selegiline

2015