bupropion and phenacetin

bupropion has been researched along with phenacetin in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (17.65)29.6817
2010's14 (82.35)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Glen, RC; Lowe, R; Mitchell, JB1
Dai, R; Liu, Y; She, M; Wu, Z1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Obach, RS; Walsky, RL1
Greenblatt, DJ; Leigh-Pemberton, RA; von Moltke, LL1
Furue, MK; Hayakawa, T; Higuchi, M; Inamura, M; Kawabata, K; Kikuchi, K; Mizuguchi, H; Nagamoto, Y; Sakurai, F; Sugawara, M; Takayama, K; Tashiro, K; Watanabe, H1
Cho, YY; Choi, JH; Hong, SW; Jeong, HU; Kong, TY; Kwon, SS; Lee, HS; Lee, JY; Yeon, SH1
Chen, M; Chen, X; Hu, G; Hu, L; Lin, G; Ma, J; Pan, J; Wang, X1
Chen, WH; Chen, ZB; Hu, LF; Li, D; Lin, FY; Yu, XG; Zhi, AY1
Guo, C; Han, YL; Liu, LY; Lu, J; Yang, QJ; Yu, Q; Zhu, JH1
Lin, C; Lin, G; Ma, J; Wang, S; Wang, X; Zhang, M; Zhang, Q; Zhou, Y1
Lin, K; Lin, Y; Liu, Z; Wen, C; Yang, S; Zhang, Q; Zheng, Y1
Mandal, A; Raju, S; Viswanathan, C1
Chen, W; Ge, T; Peng, D; Sun, J; Tang, X; Xu, Q1

Other Studies

17 other study(ies) available for bupropion and phenacetin

ArticleYear
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
The inhibition study of human UDP-glucuronosyltransferases with cytochrome P450 selective substrates and inhibitors.
    Journal of enzyme inhibition and medicinal chemistry, 2011, Volume: 26, Issue:3

    Topics: Cytochrome P-450 Enzyme Inhibitors; Enzyme Activation; Enzyme Inhibitors; Glucuronosyltransferase; Humans; Molecular Structure; Recombinant Proteins; Stereoisomerism; Structure-Activity Relationship; Substrate Specificity

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Validated assays for human cytochrome P450 activities.
    Drug metabolism and disposition: the biological fate of chemicals, 2004, Volume: 32, Issue:6

    Topics: Amodiaquine; Bupropion; Coumarins; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Diclofenac; Drug Design; Drug Evaluation, Preclinical; Drug Interactions; Enzyme Inhibitors; Humans; In Vitro Techniques; Isoenzymes; Mass Spectrometry; Microsomes, Liver; Phenacetin; Recombinant Proteins; Reproducibility of Results

2004
In vitro interactions of water-soluble garlic components with human cytochromes p450.
    The Journal of nutrition, 2006, Volume: 136, Issue:3 Suppl

    Topics: Bupropion; Cytochrome P-450 Enzyme System; Dextromethorphan; Flurbiprofen; Garlic; Humans; Isoenzymes; Kinetics; Phenacetin; Plant Extracts; Triazolam

2006
Generation of metabolically functioning hepatocytes from human pluripotent stem cells by FOXA2 and HNF1α transduction.
    Journal of hepatology, 2012, Volume: 57, Issue:3

    Topics: Bupropion; Cell Differentiation; Cell Line; Embryonic Stem Cells; Ethanolamines; Gene Transfer Techniques; Hepatocyte Nuclear Factor 1-alpha; Hepatocyte Nuclear Factor 3-beta; Hepatocytes; Humans; Induced Pluripotent Stem Cells; Midazolam; Paclitaxel; Phenacetin; Testosterone; Tolbutamide; Transduction, Genetic

2012
Effect of honokiol on cytochrome P450 and UDP-glucuronosyltransferase enzyme activities in human liver microsomes.
    Molecules (Basel, Switzerland), 2013, Sep-03, Volume: 18, Issue:9

    Topics: Aryl Hydrocarbon Hydroxylases; Biphenyl Compounds; Bupropion; Drugs, Chinese Herbal; Enzyme Inhibitors; Ethanolamines; Glucuronosyltransferase; Herb-Drug Interactions; Humans; Hydroxylation; Inactivation, Metabolic; Inhibitory Concentration 50; Lignans; Liver; Microsomes, Liver; Phenacetin

2013
Assessment of effects of chronic hydrogen sulfide poisoning on cytochrome P450 isoforms activity of rats by cocktail approach.
    Biological & pharmaceutical bulletin, 2013, Volume: 36, Issue:10

    Topics: Animals; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Bupropion; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2B6; Hydrogen Sulfide; Male; Phenacetin; Protein Isoforms; Random Allocation; Rats; Rats, Sprague-Dawley; Tolbutamide

2013
Pharmacokinetic of four probe drugs in adriamycin-induced nephropathy rat.
    European review for medical and pharmacological sciences, 2014, Volume: 18, Issue:10

    Topics: Animals; Bupropion; Cytochrome P-450 Enzyme System; Doxorubicin; Male; Nephrotic Syndrome; Omeprazole; Phenacetin; Rats, Sprague-Dawley; Tolbutamide

2014
A sensitive and high-throughput LC-MS/MS method for inhibition assay of seven major cytochrome P450s in human liver microsomes using an in vitro cocktail of probe substrates.
    Biomedical chromatography : BMC, 2015, Volume: 29, Issue:3

    Topics: Bupropion; Calibration; Chromatography, Liquid; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; High-Throughput Screening Assays; Humans; Inhibitory Concentration 50; Limit of Detection; Mephenytoin; Microsomes, Liver; Midazolam; Phenacetin; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry

2015
Simultaneous determination of bupropion, metroprolol, midazolam, phenacetin, omeprazole and tolbutamide in rat plasma by UPLC-MS/MS and its application to cytochrome P450 activity study in rats.
    Biomedical chromatography : BMC, 2015, Volume: 29, Issue:8

    Topics: Adjuvants, Anesthesia; Analgesics, Non-Narcotic; Animals; Antidepressive Agents, Second-Generation; Bupropion; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Erlotinib Hydrochloride; Hypoglycemic Agents; Limit of Detection; Male; Midazolam; Omeprazole; Pharmaceutical Preparations; Phenacetin; Protein Kinase Inhibitors; Proton Pump Inhibitors; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry; Tolbutamide

2015
Effects of suberoylanilide hydroxamic acid on rat cytochrome P450 enzyme activities.
    International journal of clinical and experimental pathology, 2015, Volume: 8, Issue:5

    Topics: Administration, Oral; Animals; Bupropion; Chemical and Drug Induced Liver Injury; Chromatography, Liquid; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2B6 Inhibitors; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C19 Inducers; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochromes; Drug Interactions; Edema; Enzyme Induction; Histone Deacetylase Inhibitors; Hydroxamic Acids; Liver; Male; Metoprolol; Omeprazole; Phenacetin; Rats, Sprague-Dawley; Substrate Specificity; Tandem Mass Spectrometry; Tolbutamide; Vorinostat

2015
Long-term culture and cryopreservation does not affect the stability and functionality of human embryonic stem cell-derived hepatocyte-like cells.
    In vitro cellular & developmental biology. Animal, 2016, Volume: 52, Issue:2

    Topics: Acetaminophen; Bupropion; Cell Culture Techniques; Cell Differentiation; Cryopreservation; Diclofenac; Hepatocytes; Human Embryonic Stem Cells; Humans; Phenacetin

2016
Effect of Gambogenic Acid on Cytochrome P450 1A2, 2B1 and 2E1, and Constitutive Androstane Receptor in Rats.
    European journal of drug metabolism and pharmacokinetics, 2018, Volume: 43, Issue:6

    Topics: Animals; Bupropion; Chlorzoxazone; Constitutive Androstane Receptor; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2B1; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme Inducers; Dose-Response Relationship, Drug; Drug Interactions; Liver; Male; Phenacetin; Rats; Receptors, Cytoplasmic and Nuclear; Xanthenes

2018