bupropion and diazepam

bupropion has been researched along with diazepam in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19903 (13.64)18.7374
1990's3 (13.64)18.2507
2000's6 (27.27)29.6817
2010's10 (45.45)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Ahman, M; Holmén, AG; Wan, H1
Antonsson, M; Bengtsson, O; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Jerndal, G; Wan, H; Winiwarter, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Glen, RC; Lowe, R; Mitchell, JB1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC1
Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F1
Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dubrovina, NI; Il'iuchenok, RIu; Parkhomenko, RI1
Patrick, GA; Rosenberger, W; Yutrzenka, GJ1
Bergman, J; Spealman, RD1
Hamilton, M; Peck, AW1
Bush, M; Hamilton, MJ; Peck, AW; Smith, P1
Storrow, AB1
Chrousos, GP; Gabry, KE; Gold, PW; McCann, SM; Mostafa, RM; Negrao, AB; Rice, KC; Sternberg, E; Webster, EL1
Aguiar, LM; de Sousa, FC; de Vasconcelos, SM; dos Santos, RS; Lima, VT; Macêdo, DS; Viana, GS1
Balci, F; Campbell, U; Hanania, T; Olivier, BE; Paterson, NE1
Hara, H; Hayashi, E; Kinoshita, M; Kuratani, K1

Reviews

2 review(s) available for bupropion and diazepam

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Bupropion overdose and seizure.
    The American journal of emergency medicine, 1994, Volume: 12, Issue:2

    Topics: Adolescent; Bupropion; Charcoal; Diazepam; Drug Overdose; Electrocardiography; Emergency Service, Hospital; Epilepsy, Tonic-Clonic; Female; Gastric Lavage; Humans; Sorbitol; Suicide, Attempted; Tachycardia, Sinus

1994

Trials

2 trial(s) available for bupropion and diazepam

ArticleYear
Psychopharmacology of bupropion in normal volunteers.
    The Journal of clinical psychiatry, 1983, Volume: 44, Issue:5 Pt 2

    Topics: Amitriptyline; Antidepressive Agents; Arousal; Auditory Perception; Blood Pressure; Bupropion; Diazepam; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Ethanol; Heart Rate; Humans; Placebos; Propiophenones; Psychomotor Performance; Reaction Time

1983
The effects of bupropion, a new antidepressant drug, and diazepam, and their interaction in man.
    British journal of clinical pharmacology, 1982, Volume: 14, Issue:6

    Topics: Adult; Antidepressive Agents; Attention; Bupropion; Diazepam; Drug Interactions; Electroencephalography; Female; Heart Rate; Humans; Male; Memory, Short-Term; Propiophenones; Psychomotor Performance; Reaction Time

1982

Other Studies

18 other study(ies) available for bupropion and diazepam

ArticleYear
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Structure-brain exposure relationships in rat and human using a novel data set of unbound drug concentrations in brain interstitial and cerebrospinal fluids.
    Journal of medicinal chemistry, 2009, Oct-22, Volume: 52, Issue:20

    Topics: Animals; Blood-Brain Barrier; Brain; Extracellular Fluid; Humans; Linear Models; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility

2010
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution

2011
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3

    Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
[GABAergic modulation of amnesic trace reproduction by activation of the dopaminergic system].
    Biulleten' eksperimental'noi biologii i meditsiny, 1990, Volume: 110, Issue:12

    Topics: Animals; Avoidance Learning; Bupropion; Diazepam; Dopamine Agents; Ergolines; Male; Mice; Mice, Inbred BALB C; Piperidines; Propiophenones; Quinpirole; Receptors, GABA-A

1990
Substitution of psychoactive drugs in pentobarbital-dependent rats.
    Drug and alcohol dependence, 1990, Volume: 26, Issue:1

    Topics: Animals; Antidepressive Agents; Arousal; Body Weight; Brain; Bromazepam; Bupropion; Diazepam; Dose-Response Relationship, Drug; Male; Mazindol; Methaqualone; Motor Activity; Nortriptyline; Phenobarbital; Propiophenones; Psychotropic Drugs; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome; Substance-Related Disorders

1990
Behavioral effects of histamine H1 antagonists: comparison with other drugs and modification by haloperidol.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 245, Issue:2

    Topics: Animals; Bupropion; Cocaine; Conditioning, Operant; Cyproheptadine; Desipramine; Diazepam; Dose-Response Relationship, Drug; Electroshock; Haloperidol; Histamine H1 Antagonists; Male; Propiophenones; Saimiri

1988
Marked suppression of gastric ulcerogenesis and intestinal responses to stress by a novel class of drugs.
    Molecular psychiatry, 2002, Volume: 7, Issue:5

    Topics: Analysis of Variance; Animals; Bupropion; Buspirone; Colon; Corticotropin-Releasing Hormone; Diazepam; Dose-Response Relationship, Drug; Fluoxetine; Gastric Mucosa; Male; Mucins; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Stomach Ulcer

2002
Cocaine alters catalase activity in prefrontal cortex and striatum of mice.
    Neuroscience letters, 2005, Oct-14, Volume: 387, Issue:1

    Topics: Adrenergic Uptake Inhibitors; Animals; Anticonvulsants; Bupropion; Catalase; Catecholamines; Cocaine; Corpus Striatum; Diazepam; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Free Radical Scavengers; Hydrogen Peroxide; Male; Mice; Mortality; Oxidative Stress; Prefrontal Cortex; Seizures; Status Epilepticus

2005
The triple reuptake inhibitor DOV216,303 exhibits limited antidepressant-like properties in the differential reinforcement of low-rate 72-second responding assay, likely due to dopamine reuptake inhibition.
    Journal of psychopharmacology (Oxford, England), 2011, Volume: 25, Issue:10

    Topics: Animals; Antidepressive Agents; Aza Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bupropion; Desipramine; Diazepam; Dopamine Uptake Inhibitors; Fluvoxamine; Haloperidol; Imipramine; Male; Piperazines; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology

2011
Pharmacologically distinctive behaviors other than burying marbles during the marble burying test in mice.
    Pharmacology, 2010, Volume: 86, Issue:5-6

    Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Behavior, Animal; Bupropion; Diazepam; Exploratory Behavior; Fluvoxamine; Imipramine; Male; Mice; Motor Activity

2010