bupropion and clopidogrel

bupropion has been researched along with clopidogrel in 7 studies

Research

Studies (7)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	4 (57.14)	29.6817
2010's	3 (42.86)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Desta, Z; Guo, Y; Ogburn, ET; Xu, C	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Eichelbaum, M; Heinkele, G; Mürdter, TE; Pleiss, J; Richter, T; Schwab, M; Tatzel, S; Zanger, UM	1
Jalonen, J; Laine, K; Pelkonen, O; Tolonen, A; Turpeinen, M; Uusitalo, J	1
Astuccio, AV; Obach, RS; Walsky, RL	1
Bateman, ND; Buchanan, D; Clark, RC; Cuthbert, M; Kerr, S; Maxwell, SR; Steinke, D; Webb, DJ	1

Reviews

1 review(s) available for bupropion and clopidogrel

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

1 trial(s) available for bupropion and clopidogrel

Article	Year
Effect of clopidogrel and ticlopidine on cytochrome P450 2B6 activity as measured by bupropion hydroxylation. Clinical pharmacology and therapeutics, 2005, Volume: 77, Issue:6 Topics: Adult; Aryl Hydrocarbon Hydroxylases; Bupropion; Clopidogrel; Cross-Over Studies; Cytochrome P-450 CYP2B6; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Humans; Hydroxylation; Male; Oxidoreductases, N-Demethylating; Platelet Aggregation Inhibitors; Ticlopidine	2005

Article

Year

Effect of clopidogrel and ticlopidine on cytochrome P450 2B6 activity as measured by bupropion hydroxylation.

Clinical pharmacology and therapeutics, 2005, Volume: 77, Issue:6

Topics: Adult; Aryl Hydrocarbon Hydroxylases; Bupropion; Clopidogrel; Cross-Over Studies; Cytochrome P-450 CYP2B6; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Humans; Hydroxylation; Male; Oxidoreductases, N-Demethylating; Platelet Aggregation Inhibitors; Ticlopidine

2005

Other Studies

5 other study(ies) available for bupropion and clopidogrel

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Effects of the CYP2B66 allele on catalytic properties and inhibition of CYP2B6 in vitro: implication for the mechanism of reduced efavirenz metabolism and other CYP2B6 substrates in vivo. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:4* Topics: Alkynes; Alleles; Aryl Hydrocarbon Hydroxylases; Benzoxazines; Biotransformation; Bupropion; Catalysis; Clopidogrel; Cyclopropanes; Cytochrome P-450 CYP2B6; Cytochromes b5; Enzyme Inhibitors; Humans; Hydroxylation; In Vitro Techniques; Kinetics; Microsomes, Liver; Oxidoreductases, N-Demethylating; Pyrimidines; Substrate Specificity; Ticlopidine; Triazoles; Voriconazole	2012
Potent mechanism-based inhibition of human CYP2B6 by clopidogrel and ticlopidine. The Journal of pharmacology and experimental therapeutics, 2004, Volume: 308, Issue:1 Topics: Aryl Hydrocarbon Hydroxylases; Bupropion; Clopidogrel; Cytochrome P-450 CYP2B6; Cytochrome P-450 Enzyme Inhibitors; Humans; Hydroxylation; Kinetics; Microsomes, Liver; Oxidoreductases, N-Demethylating; Platelet Aggregation Inhibitors; Ticlopidine	2004
Evaluation of 227 drugs for in vitro inhibition of cytochrome P450 2B6. Journal of clinical pharmacology, 2006, Volume: 46, Issue:12 Topics: Algorithms; Alkynes; Antidepressive Agents, Second-Generation; Antifungal Agents; Area Under Curve; Benzoxazines; Bupropion; Clopidogrel; Clotrimazole; Cyclopropanes; Cytochrome P-450 CYP2B6; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; Itraconazole; Kinetics; Microsomes, Liver; Molecular Structure; Oxazines; Platelet Aggregation Inhibitors; Raloxifene Hydrochloride; Reverse Transcriptase Inhibitors; Selective Estrogen Receptor Modulators; Selective Serotonin Reuptake Inhibitors; Sertraline; Ticlopidine; Xenobiotics	2006
The influence of primary care prescribing rates for new drugs on spontaneous reporting of adverse drug reactions. Drug safety, 2007, Volume: 30, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Antidepressive Agents, Second-Generation; Antimetabolites, Antineoplastic; Bupropion; Capecitabine; Citalopram; Clopidogrel; Cyclooxygenase 2 Inhibitors; Deoxycytidine; Drug Monitoring; Drug Prescriptions; Drug Utilization Review; Fluorouracil; Humans; Lactones; Meningococcal Vaccines; Platelet Aggregation Inhibitors; Primary Health Care; Scotland; Sulfones; Ticlopidine; Time Factors	2007