bupropion and benztropine

bupropion has been researched along with benztropine in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19905 (35.71)18.7374
1990's1 (7.14)18.2507
2000's4 (28.57)29.6817
2010's4 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hoffman, BT; Katz, JL; Kopajtic, T; Newman, AH1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Rothman, RB1
Kruk, ZL; Millar, J; Stamford, JA1
Kuhr, WG; May, LJ; Wightman, RM1
Brooks, JD; DeLanney, LE; Irwin, I; Langston, JW; Ricaurte, GA1
Cubeddu, LX; Hoffmann, IS; James, MK1
McKearney, JW1
Amara, SG; Mortensen, OV1

Reviews

1 review(s) available for bupropion and benztropine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

13 other study(ies) available for bupropion and benztropine

ArticleYear
2D QSAR modeling and preliminary database searching for dopamine transporter inhibitors using genetic algorithm variable selection of Molconn Z descriptors.
    Journal of medicinal chemistry, 2000, Nov-02, Volume: 43, Issue:22

    Topics: Algorithms; Binding, Competitive; Carrier Proteins; Databases, Factual; Dopamine; Dopamine Plasma Membrane Transport Proteins; Ligands; Membrane Glycoproteins; Membrane Transport Proteins; Models, Molecular; Nerve Tissue Proteins; Quantitative Structure-Activity Relationship; Radioligand Assay; Reproducibility of Results; Software

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
High affinity dopamine reuptake inhibitors as potential cocaine antagonists: a strategy for drug development.
    Life sciences, 1990, Volume: 46, Issue:20

    Topics: Benztropine; Bupropion; Cocaine; Dopamine; Drug Evaluation, Preclinical; Humans; Mazindol; Nomifensine; Propiophenones; Substance-Related Disorders

1990
Dissociation of the actions of uptake blockers upon dopamine overflow and uptake in the rat nucleus accumbens: in vivo voltammetric data.
    Neuropharmacology, 1989, Volume: 28, Issue:12

    Topics: Animals; Benztropine; Bupropion; Cocaine; Dopamine; Electric Stimulation; Electrochemistry; Levodopa; Male; Microelectrodes; Neurotransmitter Uptake Inhibitors; Nomifensine; Nucleus Accumbens; Piperazines; Propiophenones; Rats; Rats, Inbred Strains; Septal Nuclei

1989
Differentiation of dopamine overflow and uptake processes in the extracellular fluid of the rat caudate nucleus with fast-scan in vivo voltammetry.
    Journal of neurochemistry, 1988, Volume: 51, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Benztropine; Bupropion; Caudate Nucleus; Dopamine; Electric Stimulation; Electrochemistry; Extracellular Space; Kinetics; Levodopa; Male; Microelectrodes; Neurotransmitter Uptake Inhibitors; Nomifensine; Piperazines; Propiophenones; Rats; Rats, Inbred Strains

1988
Dopamine uptake blockers protect against the dopamine depleting effect of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the mouse striatum.
    Neuroscience letters, 1985, Sep-06, Volume: 59, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Benztropine; Bupropion; Corpus Striatum; Dopamine; Male; Mazindol; Mice; Mice, Inbred C57BL; Nalidixic Acid; Naphthyridines; Parasympatholytics; Propiophenones; Pyridines; Receptors, Dopamine

1985
Frequency-dependent effects of neuronal uptake inhibitors on the autoreceptor-mediated modulation of dopamine and acetylcholine release from the rabbit striatum.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 226, Issue:1

    Topics: Acetylcholine; Animals; Apomorphine; Benztropine; Bupropion; Cocaine; Corpus Striatum; Dopamine; Dopamine Antagonists; Drug Interactions; Electric Stimulation; Neurons; Nomifensine; Propiophenones; Rabbits; Sulpiride

1983
Effects of dopamine uptake inhibitors on schedule-controlled behavior in the squirrel monkey.
    Psychopharmacology, 1982, Volume: 78, Issue:4

    Topics: Animals; Behavior, Animal; Benztropine; Bupropion; Conditioning, Operant; Dopamine; Electroshock; Male; Mazindol; Nomifensine; Propiophenones; Psychotropic Drugs; Reinforcement Schedule; Saimiri

1982
Gain of function mutants reveal sites important for the interaction of the atypical inhibitors benztropine and bupropion with monoamine transporters.
    Journal of neurochemistry, 2006, Volume: 98, Issue:5

    Topics: Alanine; Animals; Benztropine; Binding, Competitive; Biological Transport; Bupropion; Chlorocebus aethiops; COS Cells; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Fluoxetine; Models, Molecular; Mutagenesis, Site-Directed; Norepinephrine Plasma Membrane Transport Proteins; Radioligand Assay; Serine; Transfection; Tritium

2006