bupropion and amitriptyline

bupropion has been researched along with amitriptyline in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199018 (47.37)18.7374
1990's1 (2.63)18.2507
2000's7 (18.42)29.6817
2010's12 (31.58)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Antonsson, M; Bengtsson, O; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Jerndal, G; Wan, H; Winiwarter, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Glen, RC; Lowe, R; Mitchell, JB1
Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F1
Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Barrett, JE; Zhang, L1
Anisman, H; Shanks, N1
Davidson, J; Pelton, S1
Barnes, JC; Costall, B; Domeney, AM; Naylor, RJ1
Mac, D; Othmer, E; Othmer, SC; Preskorn, SH1
Clifford, DB; Hicks, FG; Rutherford, JL; Zorumski, CF1
Allen, S; Davidson, J; Manberg, P; Miller, R; Parrott, R; Strickland, R; Van Wyck Fleet, J1
Amin, MM; Chouinard, G; Cooper, AJ; Mendels, J; Miles, JE; Remick, RA; Saxena, B; Secunda, SK; Singh, AN1
Chouinard, G1
Preskorn, SH1
Othmer, E; Othmer, SC; Stern, WC; Van Wyck Fleet, J1
Bustrack, J; Cohn, JB; Wenger, TL1
Stern, WC; Wenger, TL1
Cato, AE; Harto-Truax, N; Miller, LL; Sato, TL; Stern, WC1
Hamilton, M; Peck, AW1
Miller, DB; Miller, LL1
Lai, CW; Othmer, E; Othmer, SC; Preskorn, SH1
Chouinard, G; Farrell, PG; Fogel, P; Mamer, OA1
Campos, PE; Miles, JE; Misri, S; Remick, RA; Van Wyck Fleet, J1
Bennett, VL; Bowen, RC; Chlan-Fourney, J; Juorio, AV; Li, XM; Shrikhande, S1
Billups, SJ; Delate, T; Dugan, D1
Jesse, CR; Nogueira, CW; Wilhelm, EA1
Katiyar, S; Kukade, G; Mahesh, R; Pandey, DK; Rudra, A; Viyogi, S1
Blumenthal, SR; Castro, VM; Churchill, SE; Clements, CC; Erb, JL; Fava, M; Kohane, IS; Murphy, SN; Perlis, RH; Rosenfield, HR; Smoller, JW; Weilburg, JB1
Barbui, C; Cipriani, A; Furukawa, TA; Hayasaka, Y; Leucht, S; Magni, LR; Ogawa, Y; Purgato, M; Takeshima, N1
Chambers, RS; DeMonbrun, AG; Dolcourt, BA; Kawai, Y; Malas, NM; Nolan, DA; Quasney, MW1

Reviews

2 review(s) available for bupropion and amitriptyline

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
The cardiovascular profile of bupropion.
    The Journal of clinical psychiatry, 1983, Volume: 44, Issue:5 Pt 2

    Topics: Adult; Aged; Amitriptyline; Antidepressive Agents; Blood Pressure; Bupropion; Cardiovascular Diseases; Cardiovascular System; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Electrocardiography; Female; Heart Conduction System; Heart Rate; Humans; Male; Middle Aged; Propiophenones

1983

Trials

14 trial(s) available for bupropion and amitriptyline

ArticleYear
Forms of atypical depression and their response to antidepressant drugs.
    Psychiatry research, 1986, Volume: 17, Issue:2

    Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Anxiety Disorders; Bupropion; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Female; Humans; Imipramine; Isocarboxazid; Male; Middle Aged; Monoamine Oxidase Inhibitors; Panic; Phenelzine; Propiophenones; Psychological Tests; Sex Factors; Somatoform Disorders

1986
Differential effect of amitriptyline and bupropion on primary and secondary depression: a pilot study.
    The Journal of clinical psychiatry, 1988, Volume: 49, Issue:8

    Topics: Adolescent; Adult; Amitriptyline; Antidepressive Agents; Anxiety Disorders; Bupropion; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Drug Administration Schedule; Drug Evaluation; Female; Humans; Male; Pilot Projects; Propiophenones; Prospective Studies; Random Allocation

1988
A double-blind comparison of bupropion and amitriptyline in depressed inpatients.
    The Journal of clinical psychiatry, 1983, Volume: 44, Issue:5 Pt 2

    Topics: Adult; Amitriptyline; Antidepressive Agents; Appetite; Body Weight; Bupropion; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Female; Hospitalization; Humans; Male; Middle Aged; Propiophenones; Psychiatric Status Rating Scales

1983
A comparative study of bupropion and amitriptyline in depressed outpatients.
    The Journal of clinical psychiatry, 1983, Volume: 44, Issue:5 Pt 2

    Topics: Adolescent; Adult; Aged; Ambulatory Care; Amitriptyline; Antidepressive Agents; Bupropion; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Humans; Middle Aged; Propiophenones; Psychiatric Status Rating Scales; Random Allocation

1983
Bupropion and amitriptyline in the treatment of depressed patients.
    The Journal of clinical psychiatry, 1983, Volume: 44, Issue:5 Pt 2

    Topics: Adolescent; Adult; Aged; Ambulatory Care; Amitriptyline; Antidepressive Agents; Bupropion; Clinical Trials as Topic; Depressive Disorder; Female; Hospitalization; Humans; Male; Middle Aged; Propiophenones; Psychiatric Status Rating Scales

1983
Antidepressant response and plasma concentrations of bupropion.
    The Journal of clinical psychiatry, 1983, Volume: 44, Issue:5 Pt 2

    Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents; Bupropion; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Hospitalization; Humans; Middle Aged; Placebos; Propiophenones; Psychiatric Status Rating Scales

1983
Long-term efficacy and safety of bupropion.
    The Journal of clinical psychiatry, 1983, Volume: 44, Issue:5 Pt 2

    Topics: Adult; Aged; Ambulatory Care; Amitriptyline; Antidepressive Agents; Bupropion; Clinical Trials as Topic; Depressive Disorder; Female; Follow-Up Studies; Hospitalization; Humans; Male; Middle Aged; Propiophenones; Psychiatric Status Rating Scales

1983
Comparison of the effects of bupropion and amitriptyline on cardiac conduction in depressed patients.
    The Journal of clinical psychiatry, 1983, Volume: 44, Issue:5 Pt 2

    Topics: Amitriptyline; Antidepressive Agents; Bupropion; Depressive Disorder; Electrocardiography; Heart Conduction System; Humans; Propiophenones

1983
The cardiovascular profile of bupropion.
    The Journal of clinical psychiatry, 1983, Volume: 44, Issue:5 Pt 2

    Topics: Adult; Aged; Amitriptyline; Antidepressive Agents; Blood Pressure; Bupropion; Cardiovascular Diseases; Cardiovascular System; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Electrocardiography; Female; Heart Conduction System; Heart Rate; Humans; Male; Middle Aged; Propiophenones

1983
Effects of bupropion on body weight.
    The Journal of clinical psychiatry, 1983, Volume: 44, Issue:5 Pt 2

    Topics: Amitriptyline; Antidepressive Agents; Appetite; Body Weight; Bupropion; Clinical Trials as Topic; Dose-Response Relationship, Drug; Energy Intake; Humans; Placebos; Propiophenones

1983
Psychopharmacology of bupropion in normal volunteers.
    The Journal of clinical psychiatry, 1983, Volume: 44, Issue:5 Pt 2

    Topics: Amitriptyline; Antidepressive Agents; Arousal; Auditory Perception; Blood Pressure; Bupropion; Diazepam; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Ethanol; Heart Rate; Humans; Placebos; Propiophenones; Psychomotor Performance; Reaction Time

1983
Tricyclic-induced electroencephalogram abnormalities and plasma drug concentrations.
    Journal of clinical psychopharmacology, 1984, Volume: 4, Issue:5

    Topics: Adult; Aged; Amitriptyline; Antidepressive Agents; Antidepressive Agents, Tricyclic; Bupropion; Depressive Disorder; Double-Blind Method; Electroencephalography; Female; Humans; Male; Middle Aged; Nortriptyline; Propiophenones; Random Allocation

1984
Determination of plasma bupropion and its relationship to therapeutic effect.
    Biomedical mass spectrometry, 1984, Volume: 11, Issue:12

    Topics: Amitriptyline; Antidepressive Agents; Bupropion; Clinical Trials as Topic; Depression; Double-Blind Method; Female; Humans; Male; Mass Spectrometry; Propiophenones; Radioimmunoassay

1984
A comparison of the safety and efficacy of bupropion HCL and amitriptyline hcl in depressed outpatients.
    Progress in neuro-psychopharmacology & biological psychiatry, 1982, Volume: 6, Issue:4-6

    Topics: Adult; Amitriptyline; Antidepressive Agents; Bupropion; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Female; Humans; Male; Propiophenones

1982

Other Studies

23 other study(ies) available for bupropion and amitriptyline

ArticleYear
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Structure-brain exposure relationships in rat and human using a novel data set of unbound drug concentrations in brain interstitial and cerebrospinal fluids.
    Journal of medicinal chemistry, 2009, Oct-22, Volume: 52, Issue:20

    Topics: Animals; Blood-Brain Barrier; Brain; Extracellular Fluid; Humans; Linear Models; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution

2011
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3

    Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Imipramine as a discriminative stimulus.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 259, Issue:3

    Topics: Amitriptyline; Amphetamine; Animals; Bupropion; Cocaine; Columbidae; Discrimination Learning; Dose-Response Relationship, Drug; Imipramine

1991
Strain-specific effects of antidepressants on escape deficits induced by inescapable shock.
    Psychopharmacology, 1989, Volume: 99, Issue:1

    Topics: Amitriptyline; Animals; Antidepressive Agents; Bupropion; Desipramine; Electroshock; Escape Reaction; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Propiophenones; Reaction Time; Receptors, Serotonin; Species Specificity

1989
Lithium and bupropion antagonise the phasic changes in locomotor activity caused by dopamine infused into the rat nucleus accumbens.
    Psychopharmacology, 1986, Volume: 89, Issue:3

    Topics: Amitriptyline; Animals; Antidepressive Agents; Bupropion; Dopamine Antagonists; Female; Imipramine; Lithium; Motor Activity; Nomifensine; Nucleus Accumbens; Propiophenones; Rats; Rats, Inbred Strains; Septal Nuclei

1986
Acute effects of antidepressants on hippocampal seizures.
    Annals of neurology, 1985, Volume: 18, Issue:6

    Topics: Amitriptyline; Animals; Anticonvulsants; Antidepressive Agents; Bupropion; Desipramine; Epilepsy; Hippocampus; Imipramine; Maprotiline; Propiophenones; Rats; Trazodone

1985
Bupropion, d-amphetamine, and amitriptyline-induced conditioned taste aversion in rats: dose effects.
    Pharmacology, biochemistry, and behavior, 1983, Volume: 18, Issue:5

    Topics: Amitriptyline; Analysis of Variance; Animals; Antidepressive Agents; Avoidance Learning; Bupropion; Dextroamphetamine; Dose-Response Relationship, Drug; Female; Male; Propiophenones; Rats; Rats, Inbred Strains; Taste

1983
Antidepressants upregulate messenger RNA levels of the neuroprotective enzyme superoxide dismutase (SOD1).
    Journal of psychiatry & neuroscience : JPN, 2000, Volume: 25, Issue:1

    Topics: Amitriptyline; Animals; Antidepressive Agents; Bupropion; Cyclohexanols; Dose-Response Relationship, Drug; Doxepin; Gene Expression Regulation, Enzymologic; In Vitro Techniques; Neurons; PC12 Cells; Rats; RNA, Messenger; Superoxide Dismutase; Tumor Cells, Cultured; Up-Regulation; Venlafaxine Hydrochloride

2000
Evaluation of risk factors for elevated tricyclic antidepressant plasma concentrations.
    Pharmacoepidemiology and drug safety, 2009, Volume: 18, Issue:3

    Topics: Amitriptyline; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Bupropion; Case-Control Studies; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Female; Fluoxetine; Humans; Male; Middle Aged; Nortriptyline; Paroxetine; Risk Factors; Selective Serotonin Reuptake Inhibitors; Sex Factors

2009
Depression-like behavior and mechanical allodynia are reduced by bis selenide treatment in mice with chronic constriction injury: a comparison with fluoxetine, amitriptyline, and bupropion.
    Psychopharmacology, 2010, Volume: 212, Issue:4

    Topics: Amitriptyline; Analgesics; Animals; Antidepressive Agents; Behavior, Animal; Bupropion; Depression; Disease Models, Animal; Fluoxetine; Hyperalgesia; Ligation; Male; Mice; Motor Activity; Organoselenium Compounds; Pain Measurement; Sciatic Nerve; Sciatica; Swimming; Time Factors

2010
Effect of anti-depressants on neuro-behavioural consequences following impact accelerated traumatic brain injury in rats.
    Indian journal of experimental biology, 2010, Volume: 48, Issue:5

    Topics: Acceleration; Amitriptyline; Animals; Antidepressive Agents; Anxiety; Behavior, Animal; Brain Injuries; Bupropion; Citalopram; Cyclohexanols; Exploratory Behavior; Fear; Male; Neuronal Plasticity; Neurotransmitter Uptake Inhibitors; Norepinephrine; Rats; Rats, Wistar; Reflex, Startle; Serotonin; Social Behavior; Venlafaxine Hydrochloride

2010
An electronic health records study of long-term weight gain following antidepressant use.
    JAMA psychiatry, 2014, Volume: 71, Issue:8

    Topics: Adult; Amitriptyline; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Body Mass Index; Bupropion; Citalopram; Electronic Health Records; Female; Humans; Male; Middle Aged; New England; Nortriptyline; Prospective Studies; Weight Gain; Young Adult

2014
Dose equivalents of antidepressants: Evidence-based recommendations from randomized controlled trials.
    Journal of affective disorders, 2015, Jul-15, Volume: 180

    Topics: Adult; Amitriptyline; Antidepressive Agents; Bupropion; Citalopram; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Evidence-Based Medicine; Female; Fluoxetine; Fluvoxamine; Humans; Male; Middle Aged; Moclobemide; Nortriptyline; Paroxetine; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Sertraline; Treatment Outcome

2015
A Previously Healthy Adolescent With Acute Encephalopathy and Decorticate Posturing.
    Pediatrics, 2017, Volume: 139, Issue:1

    Topics: Acute Febrile Encephalopathy; Adolescent; Amitriptyline; Brain; Bupropion; Decerebrate State; Diagnosis, Differential; Emergency Service, Hospital; Female; Glasgow Coma Scale; Humans; Intensive Care Units, Pediatric; Interdisciplinary Communication; Intersectoral Collaboration; Magnetic Resonance Angiography; Magnetic Resonance Imaging; Self Medication; Serotonin Syndrome; Suicide, Attempted; Tomography, X-Ray Computed; Venlafaxine Hydrochloride

2017