bupivacaine and sodium bicarbonate

bupivacaine has been researched along with sodium bicarbonate in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19902 (6.67)18.7374
1990's16 (53.33)18.2507
2000's5 (16.67)29.6817
2010's6 (20.00)24.3611
2020's1 (3.33)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ackerman, WE; Juneja, M; Ware, TR1
Bailey, DJ; Boyce, RG; Lyons, GD; Metzinger, SE1
Hirakawa, M; Mori, K; Ueda, W1
Graham, SL; Lawrence, J1
Camu, F; Claeys, MA; Verborgh, C1
Fernando, R; Jones, HM1
Cheney, PR; Molzen, G; Tandberg, D1
Conseiller, C; Dailland, P; Jacquinot, P; Jorrot, JC; Lirzin, JD1
Benhamou, D; Bonhomme, L; Bourget, P1
Bates, JN; Chestnut, DH; Choi, WW; Geiger, M1
Axelson, JE; Douglas, MJ; Gambling, DR; Jeffery, WK; Kim, JH; McMorland, GH; Robertson, K; Ross, PL1
Danko, I; Fritz, JD; Hogan, K; Jiao, S; Latendresse, JS; Wolff, JA1
Berrada, R; Berthier, S; Boulétreau, P; Bryssine, B; Bryssine, S; Chassard, D1
Morison, DH1
Kawasaki, J; Kawazoe, T; Koitabashi, T; Miyao, H1
Woodfin, CB1
Dieterich, HJ; Mühlbauer, B; Schroeder, TH1
Ben Yehuda, Y; Boaz, M; Levine, A; Mandelberg, A; Mori, J; Serour, F1
Cheek, TG; Gaiser, RR; Gutsche, BB; Hepner, DL1
Allen, JG; Guard, BC; Milner, QJ1
Fernando, R; Reynolds, F; Robinson, J; Sun Wai, WY1
Bigeleisen, PE; Wempe, M1
Boyer, MI; Chia, B; Gelberman, RH; Goldfarb, CA; McKeon, K1
Branfield, L1
Barber, MK; Beck, RM; Engoren, M; Thomas, R; Zbierajewski, FJ1
Bedocs, P; Fettiplace, MR; Weinberg, GL1
Almendral, J; Anadón Baselga, MJ; Callejo, D; López-Menchaca, R; Melone, A; Quintela, O; Sevilla, R; Varela, O; Zaballos, M1
Fiegl, H; Gasteiger, L; Hoerner, E; Stundner, O1

Trials

10 trial(s) available for bupivacaine and sodium bicarbonate

ArticleYear
Adrenaline absorption: effect of pH in mepivacaine and bupivacaine solutions. A clinical study during halothane anesthesia.
    Acta anaesthesiologica Scandinavica, 1992, Volume: 36, Issue:7

    Topics: Absorption; Adult; Anesthesia, Inhalation; Anesthesia, Local; Bicarbonates; Blood Pressure; Bupivacaine; Epinephrine; Female; Halothane; Heart Rate; Humans; Hydrogen-Ion Concentration; Injections, Subcutaneous; Male; Mepivacaine; Middle Aged; Nerve Block; Sodium; Sodium Bicarbonate; Time Factors

1992
Onset of epidural blockade after plain or alkalinized 0.5% bupivacaine.
    Anesthesia and analgesia, 1991, Volume: 73, Issue:4

    Topics: Adult; Analgesia, Epidural; Bicarbonates; Bupivacaine; Double-Blind Method; Female; Humans; Male; Motor Neurons; Nerve Block; Postoperative Period; Sodium; Sodium Bicarbonate; Thermosensing

1991
Comparison of plain and alkalinized local anaesthetic mixtures of lignocaine and bupivacaine for elective extradural caesarean section.
    British journal of anaesthesia, 1991, Volume: 67, Issue:6

    Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Bicarbonates; Bupivacaine; Cesarean Section; Double-Blind Method; Epinephrine; Female; Humans; Lidocaine; Pregnancy; Sodium; Sodium Bicarbonate

1991
The effect of pH buffering on reducing the pain associated with subcutaneous infiltration of bupivicaine.
    The American journal of emergency medicine, 1991, Volume: 9, Issue:2

    Topics: Adult; Bicarbonates; Buffers; Bupivacaine; Double-Blind Method; Drug Combinations; Drug Stability; Humans; Hydrogen-Ion Concentration; Injections, Subcutaneous; Pain; Pain Measurement; Prospective Studies; Sodium; Sodium Bicarbonate

1991
[Alkalization of bupivacaine in the combination fentanyl-bupivacaine in epidural obstetrical analgesia].
    Annales francaises d'anesthesie et de reanimation, 1990, Volume: 9, Issue:1

    Topics: Analgesia, Epidural; Anesthesia, Obstetrical; Bicarbonates; Bupivacaine; Drug Combinations; Female; Fentanyl; Humans; Labor, Obstetric; Pregnancy; Prospective Studies; Randomized Controlled Trials as Topic; Sodium; Sodium Bicarbonate

1990
The influence of pH-adjusted 2-chloroprocaine on the quality and duration of subsequent epidural bupivacaine analgesia during labor: a randomized, double-blind study.
    Anesthesiology, 1989, Volume: 70, Issue:3

    Topics: Analgesia, Epidural; Anesthesia, Obstetrical; Anesthetics, Local; Bicarbonates; Bupivacaine; Clinical Trials as Topic; Double-Blind Method; Drug Interactions; Female; Humans; Hydrogen-Ion Concentration; Labor, Obstetric; Pregnancy; Procaine; Random Allocation; Sodium; Sodium Bicarbonate; Sodium Chloride; Solutions; Time Factors

1989
Alkalinizing local anesthetic does not decrease pain during injection for dorsal penile nerve block.
    Journal of clinical anesthesia, 1999, Volume: 11, Issue:7

    Topics: Adolescent; Adult; Alkalies; Analysis of Variance; Anesthetics, Local; Buffers; Bupivacaine; Circumcision, Male; Double-Blind Method; Humans; Hydrogen-Ion Concentration; Injections, Subcutaneous; Lidocaine; Male; Middle Aged; Needles; Nerve Block; Pain; Pain Measurement; Penis; Prospective Studies; Sodium Bicarbonate

1999
Comparison of combined spinal-epidural and low dose epidural for labour analgesia.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2000, Volume: 47, Issue:3

    Topics: Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Anesthetics, Local; Buffers; Bupivacaine; Chi-Square Distribution; Double-Blind Method; Epinephrine; Female; Fentanyl; Humans; Injections, Spinal; Motor Neurons; Nerve Block; Pain; Pain Measurement; Patient Satisfaction; Pregnancy; Prospective Studies; Sodium Bicarbonate; Time Factors; Vasoconstrictor Agents

2000
Extra-articular steroid injection: early patient response and the incidence of flare reaction.
    The Journal of hand surgery, 2007, Volume: 32, Issue:10

    Topics: Aged; Anesthetics, Local; Anti-Inflammatory Agents; Bupivacaine; De Quervain Disease; Double-Blind Method; Drug Combinations; Female; Humans; Hydrogen-Ion Concentration; Injections; Lidocaine; Male; Methylprednisolone; Methylprednisolone Acetate; Middle Aged; Pain; Pain Measurement; Prospective Studies; Sodium Bicarbonate; Time Factors; Treatment Outcome; Trigger Finger Disorder

2007
A comparison of the pain perceived during intravenous catheter insertion after injection with various local anesthetics.
    AANA journal, 2011, Volume: 79, Issue:4 Suppl

    Topics: Adult; Anesthetics, Local; Buffers; Bupivacaine; Catheterization, Peripheral; Double-Blind Method; Female; Humans; Injections, Subcutaneous; Lidocaine; Male; Middle Aged; Ohio; Pain; Procaine; Sodium Bicarbonate

2011

Other Studies

20 other study(ies) available for bupivacaine and sodium bicarbonate

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
The air-liquid interface and the pH and PCO2 of alkalinized local anaesthetic solutions.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1992, Volume: 39, Issue:4

    Topics: Air; Alkalies; Anesthesia, Local; Anesthetics, Local; Bicarbonates; Buffers; Bupivacaine; Carbon Dioxide; Hydrogen-Ion Concentration; Lidocaine; Polypropylenes; Procaine; Sodium; Sodium Bicarbonate; Surface Properties; Syringes; Time Factors

1992
Local anesthesia in rhinoplasty: a new twist?
    Ear, nose, & throat journal, 1992, Volume: 71, Issue:9

    Topics: Adult; Anesthesia, Local; Bicarbonates; Bupivacaine; Female; Humans; Injections; Lidocaine; Male; Middle Aged; Pain; Rhinoplasty; Sodium; Sodium Bicarbonate

1992
Peribulbar blockade--an alternative anaesthetic 'cocktail'.
    Australian and New Zealand journal of ophthalmology, 1992, Volume: 20, Issue:3

    Topics: Anesthesia, Local; Autonomic Nerve Block; Bicarbonates; Bupivacaine; Humans; Lidocaine; Ophthalmologic Surgical Procedures; Orbit; Sodium; Sodium Bicarbonate

1992
Factors influencing precipitation of pH-adjusted bupivacaine solutions.
    Journal of clinical pharmacy and therapeutics, 1990, Volume: 15, Issue:3

    Topics: Bicarbonates; Bupivacaine; Chemical Phenomena; Chemical Precipitation; Chemistry; Crystallization; Drug Storage; Hydrogen-Ion Concentration; Sodium; Sodium Bicarbonate; Solutions; Temperature

1990
Effect of pH-adjustment of bupivacaine on onset and duration of epidural analgesia in parturients.
    Canadian Anaesthetists' Society journal, 1986, Volume: 33, Issue:5

    Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Bicarbonates; Bupivacaine; Female; Humans; Hydrogen-Ion Concentration; Pregnancy; Sodium; Sodium Bicarbonate

1986
Pharmacological enhancement of in vivo foreign gene expression in muscle.
    Gene therapy, 1994, Volume: 1, Issue:2

    Topics: Acetic Anhydrides; Animals; beta-Galactosidase; Bupivacaine; Cobra Cardiotoxin Proteins; Elapid Venoms; Etidocaine; Gene Expression; Gene Transfer Techniques; Genes, Reporter; Injections, Intramuscular; Luciferases; Mepivacaine; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred ICR; Muscle, Skeletal; Plasmids; Rats; Rats, Sprague-Dawley; Sodium Bicarbonate

1994
[In vitro effects of the alkalinization of 0.25% bupivacaine and 2% lidocaine].
    Annales francaises d'anesthesie et de reanimation, 1994, Volume: 13, Issue:2

    Topics: Adult; Anesthesia, Conduction; Buffers; Bupivacaine; Epinephrine; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Lidocaine; Sodium Bicarbonate

1994
Alkalinization of local anaesthetics.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1995, Volume: 42, Issue:12

    Topics: Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthetics, Local; Bupivacaine; Humans; Hydrogen-Ion Concentration; Lidocaine; Sodium Bicarbonate

1995
[Changing compatibility by temperature of local anesthetics with sodium bicarbonate].
    Masui. The Japanese journal of anesthesiology, 1996, Volume: 45, Issue:3

    Topics: Anesthetics, Local; Bupivacaine; Lidocaine; Mepivacaine; Sodium Bicarbonate; Solubility; Temperature

1996
Warming bupivacaine for intradermal anesthesia.
    The Journal of family practice, 1998, Volume: 46, Issue:6

    Topics: Adult; Anesthesia, Local; Anesthetics, Local; Buffers; Bupivacaine; Double-Blind Method; Hot Temperature; Humans; Injections; Pain; Randomized Controlled Trials as Topic; Sodium Bicarbonate; Time Factors

1998
Methemoglobinemia after axillary block with bupivacaine and additional injection of lidocaine in the operative field.
    Acta anaesthesiologica Scandinavica, 1999, Volume: 43, Issue:4

    Topics: Acidosis; Alkalies; Anesthetics, Local; Antidotes; Axilla; Bupivacaine; Drug Interactions; Female; Humans; Intraoperative Care; Kidney Failure, Chronic; Lidocaine; Methemoglobinemia; Methylene Blue; Middle Aged; Myocardial Ischemia; Nerve Block; Oxidants; Protein Binding; Sodium Bicarbonate

1999
Alkalinization of amide local anaesthetics by addition of 1% sodium bicarbonate solution.
    European journal of anaesthesiology, 2000, Volume: 17, Issue:1

    Topics: Alkalies; Amides; Anesthetics, Local; Bupivacaine; Chemical Precipitation; Epinephrine; Humans; Hydrogen-Ion Concentration; Lidocaine; Ropivacaine; Safety; Sodium Bicarbonate; Temperature; Titrimetry

2000
Chemical stability of bupivacaine, lidocaine and epinephrine in pH-adjusted solutions.
    Anaesthesia, 2000, Volume: 55, Issue:9

    Topics: Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthetics, Local; Bupivacaine; Cesarean Section; Drug Stability; Drug Storage; Epinephrine; Female; Humans; Hydrogen-Ion Concentration; Lidocaine; Pregnancy; Sodium Bicarbonate

2000
Identification of the precipitate in alkalinized solutions of mepivacaine and bupivacaine at 37 degrees C.
    Journal of clinical pharmacy and therapeutics, 2001, Volume: 26, Issue:3

    Topics: Anesthetics, Local; Bupivacaine; Chemical Precipitation; Hydrogen-Ion Concentration; Mass Spectrometry; Mepivacaine; Molecular Weight; Sodium Bicarbonate

2001
Bicarbonate causing precipitation in epidural top-up solutions.
    Anaesthesia, 2010, Volume: 65, Issue:9

    Topics: Adjuvants, Anesthesia; Analgesia, Epidural; Analgesia, Obstetrical; Anesthetics, Local; Bupivacaine; Cesarean Section; Chemical Precipitation; Female; Humans; Levobupivacaine; Pregnancy; Sodium Bicarbonate

2010
Pigs and Paradigms: Stop Using Swine to Study Lipid Resuscitation.
    Anesthesia and analgesia, 2019, Volume: 129, Issue:1

    Topics: Animals; Bupivacaine; Cardiopulmonary Resuscitation; Fat Emulsions, Intravenous; Lipids; Models, Theoretical; Resuscitation; Sodium Bicarbonate; Swine

2019
Comparative Effects of Sodium Bicarbonate and Intravenous Lipid Emulsions on Reversing Bupivacaine-Induced Electrophysiological Toxicity in a Porcine Experimental Model.
    Anesthesia and analgesia, 2019, Volume: 129, Issue:1

    Topics: Action Potentials; Anesthetics, Local; Animals; Antidotes; Arrhythmias, Cardiac; Bupivacaine; Cardiotoxicity; Disease Models, Animal; Fat Emulsions, Intravenous; Heart Conduction System; Heart Rate; Recovery of Function; Sodium Bicarbonate; Sus scrofa; Time Factors

2019
Crystallization of short-acting and intermediate-acting local anesthetics when mixed with adjuvants: a semiquantitative light microscopy analysis.
    Regional anesthesia and pain medicine, 2023, Volume: 48, Issue:10

    Topics: Anesthetics, Local; Bupivacaine; Crystallization; Dexamethasone; Follow-Up Studies; Humans; Lidocaine; Mepivacaine; Microscopy; Prilocaine; Procaine; Sodium Bicarbonate

2023