bupivacaine has been researched along with propranolol in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (20.69) | 18.7374 |
| 1990's | 6 (20.69) | 18.2507 |
| 2000's | 7 (24.14) | 29.6817 |
| 2010's | 10 (34.48) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Carrupt, PA; Guillarme, D; Henchoz, Y; Rudaz, S; Veuthey, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F | 1 |
| Brouillette, WJ; Brown, GB; Zha, C | 1 |
| Artursson, P; Mateus, A; Matsson, P | 1 |
| MacDonald, J; Orser, B | 1 |
| Bassoul, B; Brugada, J; d'Athis, F; de La Coussaye, JE; Desch, G; Eledjam, JJ; Gagnol, JP; Sassine, A | 1 |
| Kambam, JR; Kinney, WW; Wright, W | 1 |
| Wood, M | 1 |
| Bowdle, TA; Freund, PR; Slattery, JT | 1 |
| Cole, JS; Pitt, BR; Rothstein, P | 1 |
| Fujimori, M; Nishimura, K; Tatekawa, S; Yukioka, H | 1 |
| Lalka, D; McNamara, PJ; Pieper, JA; Slaughter, RL; Wyman, MG | 1 |
| Satoh, H | 1 |
| Mizuyama, K; Naito, H; Okubo, N; Sato, S | 1 |
| Kilár, F | 1 |
| Chemtob, S; Deng, XF; Mulay, S; Varma, DR | 1 |
| Haginaka, J; Matsunaga, H | 1 |
| Owens, PK; Svensson, LA | 1 |
| Ichikawa, Y; Liao, CX; Terada, LS; Tomita, S; Wu, RF | 1 |
| Crommen, J; Dive, G; Fillet, M; Frederich, M; Rousseau, A; Servais, AC | 1 |
| Du, Q; Guo, H; Ren, LM; Xu, WQ; Zhang, HF; Zhao, J | 1 |
| Chen, YW; Chiu, CC; Hung, CH; Liu, KS; Wang, JJ | 1 |
1 review(s) available for bupivacaine and propranolol
| Article | Year |
|---|---|
Plasma drug binding: implications for anesthesiologists.
Topics: Age Factors; Alfentanil; Alprenolol; Anesthesia; Anesthetics; Blood Proteins; Bupivacaine; Burns; Cardiac Surgical Procedures; Chlorpromazine; Dipyridamole; Disopyramide; Etidocaine; Female; Fentanyl; Half-Life; Humans; Imipramine; Kidney Diseases; Lidocaine; Liver; Mathematics; Meperidine; Methadone; Myocardial Infarction; Orosomucoid; Prazosin; Pregnancy; Propranolol; Protein Binding; Quinidine; Serum Albumin; Sex Factors | 1986 |
1 trial(s) available for bupivacaine and propranolol
| Article | Year |
|---|---|
Propranolol reduces bupivacaine clearance.
Topics: Adult; Anesthetics, Local; Bupivacaine; Female; Half-Life; Humans; Kinetics; Lidocaine; Male; Metabolic Clearance Rate; Propranolol; Splanchnic Circulation | 1987 |
27 other study(ies) available for bupivacaine and propranolol
| Article | Year |
|---|---|
High-throughput log P determination by ultraperformance liquid chromatography: a convenient tool for medicinal chemists.
Topics: Chemical Phenomena; Chemistry, Pharmaceutical; Chemistry, Physical; Chromatography, Liquid; Mathematics; Pharmaceutical Preparations; Software | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution | 2011 |
A highly predictive 3D-QSAR model for binding to the voltage-gated sodium channel: design of potent new ligands.
Topics: Ligands; Models, Molecular; Quantitative Structure-Activity Relationship; Voltage-Gated Sodium Channels | 2014 |
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2014 |
Propranolol protection from bupivacaine toxicity.
Topics: Animals; Apnea; Bupivacaine; Calcium Channels; Heart Arrest; Propranolol; Rats; Rats, Inbred Strains; Sodium Channels | 1992 |
[Do beta adrenergic receptor blockaders increase bupivacaine cardiotoxicity?].
Topics: Adrenergic beta-Antagonists; Anesthesia, General; Animals; Blood Pressure; Bupivacaine; Dogs; Heart Conduction System; Heart Rate; Propranolol | 1990 |
Propranolol pretreatment reduces cardiorespiratory toxicity due to plain, but not epinephrine-containing, intravenous bupivacaine in rats.
Topics: Animals; Apnea; Arrhythmias, Cardiac; Bupivacaine; Electrocardiography; Epinephrine; Heart; Injections, Intravenous; Lung; Male; Preanesthetic Medication; Propranolol; Rats; Rats, Inbred Strains | 1991 |
Pulmonary extraction of [3H]bupivacaine: modification by dose, propranolol and interaction with [14C]5-hydroxytryptamine.
Topics: Amines; Animals; Biological Transport; Bupivacaine; Cardiac Output; Lung; Male; Metabolic Clearance Rate; Propranolol; Rabbits; Serotonin | 1987 |
Influence of alpha- and beta-adrenergic blockade on systemic and pulmonary hemodynamics during intravenous administration of local anesthetics.
Topics: Animals; Bupivacaine; Dogs; Hemodynamics; Hexamethonium; Hexamethonium Compounds; Injections, Intravenous; Lidocaine; Phenoxybenzamine; Propranolol; Pulmonary Circulation; Sympatholytics | 1984 |
Factors influencing serum protein binding of lidocaine in humans.
Topics: Acecainide; Blood Proteins; Bupivacaine; Disopyramide; Humans; Lidocaine; Orosomucoid; Procainamide; Propranolol; Protein Binding; Quinidine; Serum Albumin | 1981 |
Comparison of the chronotropic responses to local anesthetics (procaine, lidocaine, prilocaine, mepivacaine and bupivacaine) of the canine sinus node in situ.
Topics: Anesthetics, Local; Animals; Bupivacaine; Dogs; Dose-Response Relationship, Drug; Female; Heart Rate; Lidocaine; Male; Mepivacaine; Prilocaine; Procaine; Propranolol; Reserpine; Sinoatrial Node; Tetrodotoxin | 1981 |
Spinal anesthesia attenuates myocardial ischemia during coronary artery spasm induced by intraaortic methacholine in rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthesia, Spinal; Animals; Aorta; Bupivacaine; Coronary Vasospasm; Electrocardiography; Hemodynamics; Injections; Injections, Spinal; Male; Methacholine Chloride; Methoxamine; Myocardial Ischemia; Phentolamine; Propranolol; Rats; Rats, Wistar | 1995 |
Stereoselective interaction of drug enantiomers with human serum transferrin in capillary zone electrophoresis.
Topics: Bupivacaine; Electrophoresis, Capillary; Humans; Hydrogen-Ion Concentration; Labetalol; Pharmaceutical Preparations; Promethazine; Propranolol; Stereoisomerism; Transferrin | 1996 |
Mechanisms of the atrium-specific positive inotropic activities of quinidine- and atropine-like agents in rats.
Topics: Animals; Anti-Arrhythmia Agents; Atropine; Bupivacaine; Catecholamines; Dimethylphenylpiperazinium Iodide; Disopyramide; Heart Atria; Isoproterenol; Male; Myocardial Contraction; Propranolol; Quinidine; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Stimulation, Chemical | 1997 |
Separation of enantiomers on HPLC chiral stationary phases based on human plasma alpha1-acid glycoprotein: effect of sugar moiety on chiral recognition ability.
Topics: Alprenolol; Benzoin; Bupivacaine; Carbohydrates; Chromatography, Gel; Chromatography, High Pressure Liquid; Electrophoresis, Capillary; Glycoside Hydrolases; Glycosylation; Humans; Hydantoins; Hydrogen-Ion Concentration; Molecular Weight; Orosomucoid; Oxprenolol; Phenylbutyrates; Propionates; Propranolol; Protein Binding; Silicon Dioxide; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Stereoisomerism; Structure-Activity Relationship; Warfarin | 2000 |
Enantioselective supercritical fluid chromatography using ristocetin A chiral stationary phases.
Topics: 2,4-Dichlorophenoxyacetic Acid; Anesthetics, Local; Anti-Bacterial Agents; Bupivacaine; Chromatography, Liquid; Coumarins; Evaluation Studies as Topic; Ketoprofen; Metoprolol; Propranolol; Reagent Kits, Diagnostic; Ristocetin; Stereoisomerism; Thalidomide; Warfarin | 2000 |
Porcine FAD-containing monooxygenase metabolizes lidocaine, bupivacaine and propranolol in vitro.
Topics: Animals; Bupivacaine; Chromatography, High Pressure Liquid; Female; Lidocaine; Microsomes, Liver; Oxygenases; Propranolol; Solubility; Swine | 2004 |
Combination of capillary electrophoresis, molecular modelling and nuclear magnetic resonance to study the interaction mechanisms between single-isomer anionic cyclodextrin derivatives and basic drug enantiomers in a methanolic background electrolyte.
Topics: beta-Cyclodextrins; Bupivacaine; Electrophoresis, Capillary; Magnetic Resonance Spectroscopy; Methanol; Models, Molecular; Propranolol; Stereoisomerism | 2012 |
Differential effects of short- and long-term bupivacaine treatment on α1-adrenoceptor-mediated contraction of isolated rat aorta rings and the reversal effect of lipid emulsion.
Topics: Acetylcholine; Adrenergic alpha-2 Receptor Antagonists; Anesthetics, Local; Animals; Aorta, Thoracic; Bupivacaine; Fat Emulsions, Intravenous; Male; Phenylephrine; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents; Yohimbine | 2015 |
Clonidine as an adjuvant for propranolol enhances its effect on infiltrative cutaneous analgesia in rats.
Topics: Administration, Cutaneous; Analgesics; Anesthetics, Local; Animals; Bupivacaine; Clonidine; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Male; Propranolol; Rats, Sprague-Dawley | 2016 |