bupivacaine has been researched along with nicardipine in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (33.33) | 18.2507 |
| 2000's | 5 (41.67) | 29.6817 |
| 2010's | 3 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bruno-Blanch, L; Gálvez, J; García-Domenech, R | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Chang, G; Di, L; Huang, Y; Lin, Z; Liston, TE; Scott, DO; Troutman, MD; Umland, JP | 1 |
| Artursson, P; Mateus, A; Matsson, P | 1 |
| Kambam, JR; Kinney, WW; Matsuda, F; Wright, W | 1 |
| Attolini, L; Bruguerolle, B; Gantenbein, M; Grignon, S; Jacob, D | 1 |
| Strichartz, GR; Xiong, Z | 1 |
| Kurata, Y; Matsuda, T | 1 |
| Asada, A; Funao, T; Oda, Y; Tanaka, K | 1 |
12 other study(ies) available for bupivacaine and nicardipine
| Article | Year |
|---|---|
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship | 2003 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Species independence in brain tissue binding using brain homogenates.
Topics: Animals; Brain; Dogs; Guinea Pigs; Humans; Macaca fascicularis; Mice; Rats; Species Specificity | 2011 |
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2014 |
Nicardipine reduces the cardio-respiratory toxicity of intravenously administered bupivacaine in rats.
Topics: Analysis of Variance; Anesthesia, Conduction; Animals; Apnea; Arrhythmias, Cardiac; Bupivacaine; Heart; Heart Rate; Infusions, Intravenous; Injections, Intraperitoneal; Injections, Intravenous; Male; Nicardipine; Pentobarbital; Rats; Rats, Inbred Strains; Respiration; Survival Rate | 1990 |
Effects of calcium antagonists on binding of local anesthetics to plasma proteins and erythrocytes in mice.
Topics: Anesthetics, Local; Animals; Blood Proteins; Bupivacaine; Calcium Channel Blockers; Diltiazem; Erythrocytes; In Vitro Techniques; Lidocaine; Male; Mice; Nicardipine; Protein Binding; Verapamil | 1996 |
Inhibition by local anesthetics of Ca2+ channels in rat anterior pituitary cells.
Topics: Anesthetics, Local; Animals; Bupivacaine; Calcium Channel Blockers; Clone Cells; Dihydropyridines; Dose-Response Relationship, Drug; Lidocaine; Membrane Potentials; Nicardipine; Patch-Clamp Techniques; Pituitary Gland, Anterior; Rats | 1998 |
Effects of nicardipine and bupivacaine on early after depolarization in rabbit sinoatrial node cells: a possible mechanism of bupivacaine-induced arrhythmias.
Topics: Action Potentials; Anesthetics, Local; Animals; Arrhythmia, Sinus; Bupivacaine; Calcium Channel Blockers; Models, Cardiovascular; Nicardipine; Rabbits; Sinoatrial Node | 1999 |
Vasodilation increases the threshold for bupivacaine-induced convulsions in rats.
Topics: Adrenergic alpha-Antagonists; Anesthetics, Local; Animals; Blood Gas Analysis; Blood Pressure; Brain; Bupivacaine; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Heart Rate; Male; Nicardipine; Phentolamine; Rats; Rats, Sprague-Dawley; Seizures; Vasodilation; Vasodilator Agents | 2004 |