bupivacaine and naloxone

bupivacaine has been researched along with naloxone in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19904 (13.79)18.7374
1990's12 (41.38)18.2507
2000's9 (31.03)29.6817
2010's3 (10.34)24.3611
2020's1 (3.45)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
McDonald, JS; Rattan, AK; Tejwani, GA1
Bengtsson, M; Johnson, A; Löfström, JB; Söderlind, K1
Barnes, RK1
Durant, PA; Yaksh, TL1
Hoffmann, P; Thorén, P1
Fine, PG; Hare, BD; Milano, R1
Davies, GK; James, TL; Tolhurst-Cleaver, CL1
Barratt, P; Headland, RM1
Alvarez, J; Blanco, E; Blanco, J; Castro, A; Rodríguez, G1
Andersson, KE; Igawa, Y; Mattiasson, A; Post, C; Uvelius, B1
Bonnet, F; Gentili, M1
Brennum, J1
Wishaw, K1
Barjhoux, CE; Danel, VC; Lemoigne, AH; Mallaret, MP; Piquet, CY; Vincent, FH1
Bläss, J; Sjöström, S1
Halpern, S; Katsiris, S; Leighton, BL; Williams, S1
Bishop, MJ; Choi, JH; Lee, J1
Bishop, MJ; Choi, JH; Kim, ES; Kwon, OK; Lee, J; Moon, DE; Shim, JY1
Celik, JB; Okesli, S; Reisli, R; Sarkilar, G1
Barrett, J; Blanchard, JW; Breen, TW; Campbell, DC; Halpern, SH; Liston, R; Muir, H1
Choi, JH; Kim, ES; Lee, J1
Damen, J; Fikkers, BG; Kruithof, HC; Scheffer, GJ1
Biber, B; Björklund, U; Forshammar, J; Hansson, E; Jörneberg, P; Lundborg, C; Westerlund, A1
Aghajani, Y; Azimaraghi, O; Barzin, G; Marashi, SM; Movafegh, A; Sharifnia, HR1
Copenhaver, DJ; Jung, MJ; Klineberg, EO; Sanghvi, C; Su, T; Yaksh, TL1

Trials

8 trial(s) available for bupivacaine and naloxone

ArticleYear
Influence of intrathecal morphine and naloxone intervention on postoperative ventilatory regulation in elderly patients.
    Acta anaesthesiologica Scandinavica, 1992, Volume: 36, Issue:5

    Topics: Aged; Aged, 80 and over; Anesthesia, Spinal; Bupivacaine; Depression, Chemical; Double-Blind Method; Female; Hip Prosthesis; Humans; Infusions, Intravenous; Male; Middle Aged; Morphine; Naloxone; Postoperative Complications; Respiration

1992
The effects of myofascial trigger point injections are naloxone reversible.
    Pain, 1988, Volume: 32, Issue:1

    Topics: Adult; Bupivacaine; Double-Blind Method; Endorphins; Female; Humans; Male; Myofascial Pain Syndromes; Naloxone; Random Allocation

1988
Spinal clonidine produces less urinary retention than spinal morphine.
    British journal of anaesthesia, 1996, Volume: 76, Issue:6

    Topics: Adult; Aged; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Clonidine; Double-Blind Method; Female; Hip Joint; Humans; Male; Middle Aged; Morphine; Naloxone; Narcotic Antagonists; Urinary Catheterization; Urinary Retention

1996
Postoperative analgesia with epidural bupivacaine and low-dose fentanyl--a comparison of two concentrations.
    Acta anaesthesiologica Scandinavica, 1998, Volume: 42, Issue:7

    Topics: Aged; Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Buprenorphine; Colon; Cough; Fentanyl; Follow-Up Studies; Humans; Infusion Pumps; Injections, Intravenous; Leg; Middle Aged; Muscle Weakness; Naloxone; Narcotic Antagonists; Pain Measurement; Pain, Postoperative; Rectum; Respiration

1998
Epidural naloxone reduces pruritus and nausea without affecting analgesia by epidural morphine in bupivacaine.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2000, Volume: 47, Issue:1

    Topics: Adult; Analgesia, Epidural; Analgesics, Opioid; Bupivacaine; Dose-Response Relationship, Drug; Female; Humans; Middle Aged; Morphine; Naloxone; Narcotic Antagonists; Nausea; Pruritus

2000
Epidural naloxone reduces intestinal hypomotility but not analgesia of epidural morphine.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2001, Volume: 48, Issue:1

    Topics: Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Female; Gastrectomy; Gastrointestinal Diseases; Gastrointestinal Motility; Humans; Injections, Epidural; Male; Middle Aged; Morphine; Naloxone; Narcotic Antagonists; Pain Measurement; Pain, Postoperative

2001
A multicenter randomized controlled trial comparing patient-controlled epidural with intravenous analgesia for pain relief in labor.
    Anesthesia and analgesia, 2004, Volume: 99, Issue:5

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anesthetics, Local; Apgar Score; Bupivacaine; Canada; Cesarean Section; Dose-Response Relationship, Drug; Double-Blind Method; Dystocia; Female; Fentanyl; Humans; Infant, Newborn; Injections, Intravenous; Naloxone; Narcotic Antagonists; Patient Compliance; Pregnancy; Treatment Outcome

2004
Naloxone added to bupivacaine or bupivacaine-fentanyl prolongs motor and sensory block during supraclavicular brachial plexus blockade: a randomized clinical trial.
    Acta anaesthesiologica Scandinavica, 2015, Volume: 59, Issue:7

    Topics: Adjuvants, Anesthesia; Adult; Anesthetics, Local; Brachial Plexus; Brachial Plexus Block; Bupivacaine; Drug Synergism; Drug Therapy, Combination; Female; Fentanyl; Humans; Male; Motor Activity; Naloxone; Narcotic Antagonists; Pain, Postoperative; Time Factors

2015

Other Studies

21 other study(ies) available for bupivacaine and naloxone

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Role of spinal opioid receptors in the antinociceptive interactions between intrathecal morphine and bupivacaine.
    Anesthesia and analgesia, 1992, Volume: 74, Issue:5

    Topics: Analgesics; Animals; Bupivacaine; Dose-Response Relationship, Drug; Drug Synergism; Enkephalin, Leucine; Injections, Spinal; Male; Morphine; Naloxone; Pain; Rats; Rats, Inbred Strains; Receptors, Opioid; Spinal Cord

1992
Delayed subarachnoid migration of an epidural catheter.
    Anaesthesia and intensive care, 1990, Volume: 18, Issue:4

    Topics: Aged; Analgesia, Epidural; Anesthesia, Epidural; Blood Pressure; Bupivacaine; Catheterization; Female; Fentanyl; Humans; Naloxone; Subarachnoid Space

1990
Epidural injections of bupivacaine, morphine, fentanyl, lofentanil, and DADL in chronically implanted rats: a pharmacologic and pathologic study.
    Anesthesiology, 1986, Volume: 64, Issue:1

    Topics: Analgesia; Analgesics, Opioid; Animals; Behavior, Animal; Bupivacaine; Catheterization; Catheters, Indwelling; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Epidural Space; Fentanyl; Male; Morphine; Motor Activity; Naloxone; Rats; Rats, Inbred Strains; Reaction Time; Time Factors

1986
Electric muscle stimulation in the hind leg of the spontaneously hypertensive rat induces a long-lasting fall in blood pressure.
    Acta physiologica Scandinavica, 1988, Volume: 133, Issue:2

    Topics: Afferent Pathways; Animals; Blood Pressure; Bupivacaine; Electric Stimulation; Fenclonine; Heart Rate; Hindlimb; Male; Muscle Contraction; Muscles; Naloxone; Rats; Rats, Inbred SHR; Sciatic Nerve; Time Factors

1988
Respiratory depression after intrathecal narcotics.
    Anaesthesia, 1980, Volume: 35, Issue:11

    Topics: Adult; Aged; Analgesia; Anesthesia, Spinal; Bupivacaine; Female; Humans; Injections, Spinal; Male; Middle Aged; Morphine; Naloxone; Postoperative Period; Respiratory Insufficiency

1980
Respiratory depression associated with spinal narcotic anaesthesia.
    The Medical journal of Australia, 1995, Oct-02, Volume: 163, Issue:7

    Topics: Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Female; Humans; Infant, Newborn; Male; Morphine; Naloxone; Narcotics; Respiration; Respiratory Insufficiency

1995
One year's experience with an acute pain service in a Spanish University Clinic hospital.
    European journal of anaesthesiology, 1994, Volume: 11, Issue:5

    Topics: Academic Medical Centers; Analgesia, Epidural; Analgesia, Patient-Controlled; Bupivacaine; Fentanyl; Hospitals, University; Humans; Infusion Pumps; Monitoring, Physiologic; Morphine; Naloxone; Pain Clinics; Pain Measurement; Pain, Postoperative; Pruritus; Respiration; Respiration Disorders; Spain

1994
A rat model for investigation of spinal mechanisms in detrusor instability associated with infravesical outflow obstruction.
    Urological research, 1993, Volume: 21, Issue:4

    Topics: Animals; Bupivacaine; Disease Models, Animal; Female; Hypertrophy; Injections, Spinal; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Rats; Rats, Sprague-Dawley; Spinal Cord; Urinary Bladder; Urinary Bladder Neck Obstruction

1993
Quantitative sensory examination of epidural anaesthesia and analgesia in man.
    Acta physiologica Scandinavica. Supplementum, 1996, Volume: 634

    Topics: Analgesia, Epidural; Analgesics, Opioid; Anesthesia, Epidural; Anesthetics, Local; Bupivacaine; Evoked Potentials, Somatosensory; Humans; Hyperalgesia; Morphine; Naloxone; Narcotic Antagonists; Nociceptors; Pain Threshold; Time Factors; Wounds and Injuries

1996
Hypothermia associated with subarachnoid morphine.
    Anaesthesia and intensive care, 1997, Volume: 25, Issue:5

    Topics: Adult; Analgesics, Opioid; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Body Temperature Regulation; Bupivacaine; Cesarean Section; Female; Fentanyl; Humans; Hypothermia; Morphine; Naloxone; Narcotic Antagonists; Nerve Block; Pregnancy; Subarachnoid Space

1997
Respiratory depression following administration of intrathecal bupivacaine to an opioid-dependent patient.
    The Annals of pharmacotherapy, 1998, Volume: 32, Issue:6

    Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Drug Interactions; Fatal Outcome; Female; Humans; Male; Morphine; Naloxone; Narcotic Antagonists; Respiratory Insufficiency

1998
Respiratory arrest following intrathecal injection of sufentanil and bupivacaine in a parturient.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1998, Volume: 45, Issue:9

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Apnea; Bupivacaine; Female; Humans; Injections, Intravenous; Injections, Spinal; Naloxone; Narcotic Antagonists; Pregnancy; Respiration, Artificial; Resuscitation; Sufentanil

1998
Respiratory arrest after intrathecal injection of sufentanil and bupivacaine.
    Acta anaesthesiologica Scandinavica, 2004, Volume: 48, Issue:6

    Topics: Adult; Anesthetics, Intravenous; Anesthetics, Local; Apnea; Bupivacaine; Drug Combinations; Humans; Injections, Spinal; Male; Naloxone; Narcotic Antagonists; Oxygen; Positive-Pressure Respiration; Pruritus; Sleep Stages; Sufentanil

2004
Optimal dose range of epidural naloxone to reduce nausea in patients receiving epidural morphine.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2004, Volume: 51, Issue:10

    Topics: Analgesia, Epidural; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Bupivacaine; Dose-Response Relationship, Drug; Humans; Hysterectomy; Morphine; Naloxone; Narcotic Antagonists; Pain Measurement; Postoperative Nausea and Vomiting; Time Factors; Treatment Outcome

2004
Thoracic epidural analgesia and antihypertensive therapy: a matter of timing?
    European journal of anaesthesiology, 2006, Volume: 23, Issue:10

    Topics: Aged; Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Antihypertensive Agents; Bupivacaine; Carcinoma; Cardiotonic Agents; Dobutamine; Enalapril; Female; Humans; Hypertension; Hypotension; Liver Neoplasms; Metoprolol; Morphine; Naloxone; Narcotic Antagonists; Norepinephrine; Thoracic Vertebrae; Time Factors; Vasoconstrictor Agents

2006
Anti-inflammatory substances can influence some glial cell types but not others.
    Brain research, 2013, Nov-20, Volume: 1539

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bupivacaine; Cells, Cultured; Cerebral Cortex; Cytokines; Lipopolysaccharides; Microglia; Naloxone; Ouabain; Rats; Toll-Like Receptor 4

2013
Severe altered mentation due to cervicothoracic intrathecal pump after correction of cervical stenosis: a case report.
    Regional anesthesia and pain medicine, 2021, Volume: 46, Issue:12

    Topics: Analgesics, Opioid; Bupivacaine; Cervical Vertebrae; Constriction, Pathologic; Humans; Injections, Spinal; Male; Middle Aged; Morphine; Naloxone; Spinal Stenosis

2021