bupivacaine has been researched along with metoprolol in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (11.76) | 18.7374 |
| 1990's | 3 (17.65) | 18.2507 |
| 2000's | 8 (47.06) | 29.6817 |
| 2010's | 3 (17.65) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Carrupt, PA; Guillarme, D; Henchoz, Y; Rudaz, S; Veuthey, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Artursson, P; Mateus, A; Matsson, P | 1 |
| Blomberg, S; Emanuelsson, H; Kock, M; Lomsky, M; Ricksten, SE; Strömblad, SO | 1 |
| Blomberg, S; Ricksten, SE | 2 |
| Matjasko, J; Roitman, K; Sprung, J; Wallace, M | 1 |
| Durkin, D; Foley, JP | 1 |
| Owens, PK; Svensson, LA | 1 |
| Damen, J; Fikkers, BG; Kruithof, HC; Scheffer, GJ | 1 |
| Bräuer, A; Hein, S; Popov, AF; Quintel, M; Schmitto, JD; Schöndube, FA | 1 |
| Chen, YW; Chou, AK | 1 |
17 other study(ies) available for bupivacaine and metoprolol
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
High-throughput log P determination by ultraperformance liquid chromatography: a convenient tool for medicinal chemists.
Topics: Chemical Phenomena; Chemistry, Pharmaceutical; Chemistry, Physical; Chromatography, Liquid; Mathematics; Pharmaceutical Preparations; Software | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2014 |
Thoracic epidural anesthesia improves global and regional left ventricular function during stress-induced myocardial ischemia in patients with coronary artery disease.
Topics: Aged; Analgesia, Epidural; Bupivacaine; Coronary Disease; Exercise Test; Female; Hemodynamics; Humans; Male; Metoprolol; Middle Aged; Myocardial Infarction; Ventricular Function, Left | 1990 |
Effects of thoracic epidural anaesthesia on central haemodynamics compared to cardiac beta adrenoceptor blockade in conscious rats with acute myocardial infarction.
Topics: Anesthesia, Epidural; Animals; Blood Pressure; Bupivacaine; Cardiac Output; Consciousness; Heart Rate; Hemodynamics; Male; Metoprolol; Myocardial Infarction; Rats; Rats, Inbred Strains; Stroke Volume; Thoracic Vertebrae; Vascular Resistance | 1990 |
Thoracic epidural anesthesia in conscious and anaesthetized rats. Effects on central haemodynamics compared to cardiac beta adrenoceptor and ganglionic blockade.
Topics: Adrenergic beta-Antagonists; Anesthesia, Epidural; Animals; Bupivacaine; Ganglionic Blockers; Hemodynamics; Hexamethonium Compounds; Male; Metoprolol; Rats; Rats, Inbred Strains; Thoracic Vertebrae; Wakefulness | 1988 |
Enhancement of bupivacaine cardiotoxicity with cardiac glycosides and beta-adrenergic blockers: a case report.
Topics: Aged; Bupivacaine; Digoxin; Drug Interactions; Female; Heart; Humans; Intercostal Nerves; Metoprolol; Nerve Block; Pain, Postoperative | 1993 |
Dual-opposite injection electrokinetic chromatography for the unbiased, simultaneous separation of cationic and anionic compounds.
Topics: Anions; Benzoates; Bupivacaine; Cations; Chromatography; Disopyramide; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Metoprolol; Sensitivity and Specificity; Surface-Active Agents | 2000 |
Enantioselective supercritical fluid chromatography using ristocetin A chiral stationary phases.
Topics: 2,4-Dichlorophenoxyacetic Acid; Anesthetics, Local; Anti-Bacterial Agents; Bupivacaine; Chromatography, Liquid; Coumarins; Evaluation Studies as Topic; Ketoprofen; Metoprolol; Propranolol; Reagent Kits, Diagnostic; Ristocetin; Stereoisomerism; Thalidomide; Warfarin | 2000 |
Thoracic epidural analgesia and antihypertensive therapy: a matter of timing?
Topics: Aged; Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Antihypertensive Agents; Bupivacaine; Carcinoma; Cardiotonic Agents; Dobutamine; Enalapril; Female; Humans; Hypertension; Hypotension; Liver Neoplasms; Metoprolol; Morphine; Naloxone; Narcotic Antagonists; Norepinephrine; Thoracic Vertebrae; Time Factors; Vasoconstrictor Agents | 2006 |
Perioperative myocardial infarction after cesarean section in a young woman with hypertrophic obstructive cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Blood Pressure; Bupivacaine; Cardiomyopathy, Hypertrophic; Cesarean Section; Ephedrine; Female; Heart Rate; Humans; Hypertension; Hypotension; Metoprolol; Myocardial Infarction; Oxytocics; Oxytocin; Postoperative Complications; Postpartum Period; Tachycardia; Vasoconstrictor Agents | 2008 |
Beta-blocker carteolol and oxprenolol produce cutaneous analgesia in response to needle pinpricks in the rat.
Topics: Acebutolol; Analgesia; Anesthetics, Local; Animals; Bupivacaine; Butoxamine; Carteolol; Dose-Response Relationship, Drug; Epinephrine; Metoprolol; Oxprenolol; Pain; Rats; Rats, Sprague-Dawley | 2023 |