bupivacaine and indomethacin

bupivacaine has been researched along with indomethacin in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19904 (14.81)18.7374
1990's7 (25.93)18.2507
2000's6 (22.22)29.6817
2010's8 (29.63)24.3611
2020's2 (7.41)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chang, G; Di, L; Huang, Y; Lin, Z; Liston, TE; Scott, DO; Troutman, MD; Umland, JP1
Artursson, P; Mateus, A; Matsson, P1
Bigler, D; Bukhave, K; Cruickshank, AM; Honnens, M; Kehlet, H; Schulze, S; Shenkin, A; Sommer, P1
Bang, U; Kehlet, H; Møller, IW; Rye, B; Schulze, S1
Aasly, J; Fredriksen, T; Sjaastad, O; Wysocka Bakowska, MM1
Hasselstrøm, L; Jensen, NH; Kehlet, H; Roikjaer, O; Schulze, S1
Zenk, KE1
Fukuda, H; Hirabayashi, Y; Horiguchi, Y; Hotta, K; Mitsuhata, H; Saitoh, J; Saitoh, K; Shimizu, R1
Boylan, JF; Katz, J; Kavanagh, BP; Laws, AK; Nierenberg, H; Roger, S; Sandler, AN1
Fujii, Y; Tanaka, H; Toyooka, H1
Hanaoka, K; Nishiyama, T; Yokoyama, T1
Hanaoka, K; Matsukawa, T; Nishiyama, T1
Page, GG1
Pietkiewicz, J; Placzek, M; Sznitowska, M1
Bai, ZT; Chai, ZF; Ji, YH; Liu, T; Pang, XY1
Bai, ZT; Cheng, M; Hua, LM; Ji, YH; Jiang, F; Liu, T; Pang, XY; Shi, J; Shu, XQ; Zhang, JW; Zhou, JJ1
Barón, J; Campos-Blanco, DM; Cortijo, E; de la Cruz, C; Fernández, R; Guerrero-Peral, ÁL; Herrero-Velázquez, S; Marco-Llorente, J; Mulero, P; Pedraza, M; Rojo-Martínez, E; Ruiz, M1
Markowitz, S; Wende, O1
Chou, YC; Hsu, YH; Huang, CT; Lee, CH; Liu, SJ; Yu, PC; Yu, YH1

Reviews

2 review(s) available for bupivacaine and indomethacin

ArticleYear
An overview of perinatal clinical pharmacology.
    Clinics in laboratory medicine, 1981, Volume: 1, Issue:2

    Topics: Abnormalities, Drug-Induced; Analgesics; Bupivacaine; Carbamazepine; Chloramphenicol; Diazepam; Digoxin; Female; Fetus; Furosemide; Gentamicins; Humans; Indomethacin; Infant, Newborn; Infant, Newborn, Diseases; Lidocaine; Penicillins; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Tetracycline; Theophylline

1981
The immune-suppressive effects of pain.
    Advances in experimental medicine and biology, 2003, Volume: 521

    Topics: Analgesics, Opioid; Animals; Bupivacaine; Cyclooxygenase Inhibitors; Fentanyl; Humans; Immune Tolerance; Immunologic Deficiency Syndromes; Indomethacin; Interleukins; Laparotomy; Mice; Models, Neurological; Morphine; Neoplasm Metastasis; Neoplasm Transplantation; Neuroimmunomodulation; Pain; Postoperative Complications; Rats; Rats, Inbred F344; Stress, Psychological

2003

Trials

6 trial(s) available for bupivacaine and indomethacin

ArticleYear
Effect of combined prednisolone, epidural analgesia, and indomethacin on the systemic response after colonic surgery.
    Archives of surgery (Chicago, Ill. : 1960), 1992, Volume: 127, Issue:3

    Topics: Acetaminophen; Activities of Daily Living; Aged; Analgesia, Epidural; Body Temperature; Bupivacaine; C-Reactive Protein; Colonic Diseases; Drug Therapy, Combination; Fatigue; Female; Humans; Indomethacin; Interleukin-6; Leukocyte Count; Male; Methylprednisolone Hemisuccinate; Morphine; Nerve Block; Pain Measurement; Pain, Postoperative; Prostaglandins E; Respiratory Function Tests

1992
Epidural bupivacaine and morphine plus systemic indomethacin eliminates pain but not systemic response and convalescence after cholecystectomy.
    Surgery, 1988, Volume: 103, Issue:3

    Topics: Adult; Aged; Blood Cells; Blood Chemical Analysis; Bupivacaine; Cholecystectomy; Convalescence; Drug Therapy, Combination; Female; Humans; Indomethacin; Injections, Epidural; Male; Middle Aged; Morphine; Pain, Postoperative; Random Allocation

1988
[Effect of indomethacin as an adjunct to postoperative pain relief by continuous epidural infusion of bupivacaine and buprenorphine].
    Masui. The Japanese journal of anesthesiology, 1994, Volume: 43, Issue:10

    Topics: Abdomen; Administration, Rectal; Aged; Analgesia, Epidural; Bupivacaine; Buprenorphine; Drug Therapy, Combination; Female; Humans; Indomethacin; Male; Middle Aged; Pain, Postoperative

1994
Multimodal analgesia before thoracic surgery does not reduce postoperative pain.
    British journal of anaesthesia, 1994, Volume: 73, Issue:2

    Topics: Adult; Aged; Analgesia; Analgesics; Bupivacaine; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Indomethacin; Male; Middle Aged; Morphine; Pain, Postoperative; Preanesthetic Medication; Thoracotomy

1994
Efficacy of thoracic epidural analgesia following laparoscopic cholecystectomy.
    European journal of anaesthesiology, 1998, Volume: 15, Issue:3

    Topics: Adult; Aged; Analgesia, Epidural; Analgesics, Opioid; Analysis of Variance; Anesthesia, Inhalation; Anesthetics, Inhalation; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Bupivacaine; Cholecystectomy, Laparoscopic; Drug Combinations; Female; Follow-Up Studies; Humans; Indomethacin; Isoflurane; Male; Middle Aged; Morphine; Nitrous Oxide; Oxygen; Pain Measurement; Pain, Postoperative; Placebos; Thoracic Vertebrae

1998
Midazolam improves postoperative epidural analgesia with continuous infusion of local anaesthetics.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1998, Volume: 45, Issue:6

    Topics: Adjuvants, Anesthesia; Adult; Aged; Analgesia, Epidural; Analgesics; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Bupivacaine; Consciousness; Drug Combinations; Drug Synergism; Female; Gastrectomy; Heart Rate; Humans; Indomethacin; Laparotomy; Male; Memory; Midazolam; Middle Aged; Pain Measurement; Pain, Postoperative; Respiration; Suppositories

1998

Other Studies

19 other study(ies) available for bupivacaine and indomethacin

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Species independence in brain tissue binding using brain homogenates.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7

    Topics: Animals; Brain; Dogs; Guinea Pigs; Humans; Macaca fascicularis; Mice; Rats; Species Specificity

2011
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
    Journal of medicinal chemistry, 2014, Apr-10, Volume: 57, Issue:7

    Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2014
Effect of combined prednisolone, epidural analgesia and indomethacin on pain, systemic response and convalescence after cholecystectomy.
    Acta chirurgica Scandinavica, 1990, Volume: 156, Issue:3

    Topics: Adult; Aged; Analgesia, Epidural; Bupivacaine; Combined Modality Therapy; Female; Humans; Indomethacin; Male; Methylprednisolone; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Preanesthetic Medication

1990
Chronic paroxysmal hemicrania. X. On the autonomic involvement.
    Cephalalgia : an international journal of headache, 1986, Volume: 6, Issue:2

    Topics: Atropine; Autonomic Nerve Block; Autonomic Nervous System; Bupivacaine; Chronic Disease; Cornea; Female; Forehead; Hot Temperature; Humans; Indomethacin; Intraocular Pressure; Migraine Disorders; Moxisylyte; Pulse; Skin Temperature; Stellate Ganglion; Sweating; Time Factors; Tonometry, Ocular

1986
Continuous epidural administration of midazolam and bupivacaine for postoperative analgesia.
    Acta anaesthesiologica Scandinavica, 1999, Volume: 43, Issue:5

    Topics: Adjuvants, Anesthesia; Administration, Rectal; Adult; Aged; Analgesia, Epidural; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Bupivacaine; Cholecystectomy; Consciousness; Female; Gastrectomy; Heart Rate; Humans; Indomethacin; Male; Memory; Midazolam; Middle Aged; Pain, Postoperative; Respiration; Sensation; Suppositories

1999
The expulsion of lipophilic drugs from the cores of solid lipid microspheres in diluted suspensions and in concentrates.
    International journal of pharmaceutics, 2006, Mar-09, Volume: 310, Issue:1-2

    Topics: Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Bupivacaine; Crystallization; Drug Carriers; Glycerides; Indomethacin; Microspheres; Particle Size; Solubility; Suspensions; Water

2006
Rat pain-related responses induced by experimental scorpion BmK sting.
    European journal of pharmacology, 2006, Dec-15, Volume: 552, Issue:1-3

    Topics: Analgesics, Opioid; Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bupivacaine; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Hyperalgesia; Indomethacin; Morphine; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Scorpion Venoms; Scorpions; Skin; Time Factors

2006
Phenotypes and peripheral mechanisms underlying inflammatory pain-related behaviors induced by BmK I, a modulator of sodium channels.
    Experimental neurology, 2010, Volume: 226, Issue:1

    Topics: Analgesics, Opioid; Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Bupivacaine; Capsaicin; Ganglia, Spinal; Indomethacin; Inflammation; Male; Morphine; Neurons; Pain; Pain Measurement; Patch-Clamp Techniques; Phenotype; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Scorpion Venoms; Sodium Channel Blockers

2010
[Hemicrania continua: characteristics and therapeutic experience in a series of 36 patients].
    Revista de neurologia, 2012, Sep-01, Volume: 55, Issue:5

    Topics: Adolescent; Adult; Age of Onset; Aged; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Bupivacaine; Chronic Disease; Female; Humans; Indomethacin; Injections; Magnetic Resonance Imaging; Male; Mepivacaine; Middle Aged; Migraine Disorders; Nerve Block; Ophthalmic Nerve; Symptom Assessment; Triamcinolone; Trochlear Nerve; Young Adult

2012
Headache from clinically confirmed hemicrania continua arising from the sternocleidomastoid muscle: a case report.
    BMC neurology, 2021, May-03, Volume: 21, Issue:1

    Topics: Aged; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Bupivacaine; Humans; Indomethacin; Lidocaine; Male; Neck Muscles; Pain, Referred; Trigeminal Autonomic Cephalalgias

2021
Anti-Adhesive Resorbable Indomethacin/Bupivacaine-Eluting Nanofibers for Tendon Rupture Repair: In Vitro and In Vivo Studies.
    International journal of molecular sciences, 2023, Nov-12, Volume: 24, Issue:22

    Topics: Adhesives; Animals; Bupivacaine; Indomethacin; Nanofibers; Polyglycolic Acid; Rats; Tendon Injuries; Tendons

2023