bupivacaine and antipyrine

bupivacaine has been researched along with antipyrine in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19906 (40.00)18.7374
1990's4 (26.67)18.2507
2000's4 (26.67)29.6817
2010's1 (6.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Carson, RJ; Gaylard, DG; Reynolds, F1
Carson, RJ; Laishley, RS; Reynolds, F1
Knott, C; Reynolds, F; Vella, LM1
Boel, J; Døssing, M; Hansen, SH; Kyst, A; Loft, S; Rasmussen, B1
Crosby, G1
Hamshaw-Thomas, A; Reynolds, F1
Neuvonen, PJ; Oikkonen, M; Rosenberg, PH1
Arney, TL; Downing, JW; Gonzalez, H; Herman, N; Johnson, HV; Johnson, RF1
Schmutz, A; Stotzer, R; Thormann, W; Wolfisberg, H1
Ala-Kokko, TI; Herva, R; Hollmén, AI; Pelkonen, O; Pienimäki, P; Vähäkangas, K1
Jasti, B; Kulkarni, U; Li, X; Mahalingam, R; Pather, SI1

Trials

1 trial(s) available for bupivacaine and antipyrine

ArticleYear
Increased hepatic microsomal enzyme activity after surgery under halothane or spinal anesthesia.
    Anesthesiology, 1985, Volume: 62, Issue:1

    Topics: Adolescent; Adult; Aminopyrine; Anesthesia, Spinal; Antipyrine; Breath Tests; Bupivacaine; Enzyme Induction; Female; Halothane; Humans; Male; Microsomes, Liver; Middle Aged; Random Allocation; Saliva; Time Factors

1985

Other Studies

14 other study(ies) available for bupivacaine and antipyrine

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Effect of umbilical perfusate pH and controlled maternal hypotension on placental drug transfer in the rabbit.
    Anesthesia and analgesia, 1990, Volume: 71, Issue:1

    Topics: Anesthesia, Obstetrical; Animals; Antipyrine; Bupivacaine; Chromatography, Gas; Female; Hydrogen-Ion Concentration; Hypotension; Infusions, Intravenous; Maternal-Fetal Exchange; Meperidine; Placenta; Pregnancy; Rabbits

1990
Effect of adrenaline on placental transfer of bupivacaine in the perfused in situ rabbit placenta.
    British journal of anaesthesia, 1989, Volume: 63, Issue:4

    Topics: Animals; Antipyrine; Blood Pressure; Bupivacaine; Epinephrine; Female; Placenta; Pregnancy; Rabbits

1989
Transfer of fentanyl across the rabbit placenta. Effect of umbilical flow and concurrent drug administration.
    British journal of anaesthesia, 1986, Volume: 58, Issue:1

    Topics: Analgesics; Animals; Antipyrine; Bupivacaine; Female; Fentanyl; Fetal Blood; Kinetics; Maternal-Fetal Exchange; Meperidine; Pregnancy; Rabbits; Regional Blood Flow

1986
Local spinal cord blood flow and glucose utilization during spinal anesthesia with bupivacaine in conscious rats.
    Anesthesiology, 1985, Volume: 63, Issue:1

    Topics: Anesthesia, Spinal; Animals; Antipyrine; Autoradiography; Blood Glucose; Bupivacaine; Deoxyglucose; Glucose; Male; Rats; Rats, Inbred Strains; Regional Blood Flow; Spinal Cord

1985
Placental transfer of bupivacaine, pethidine and lignocaine in the rabbit. Effect of umbilical flow rate and protein content.
    British journal of obstetrics and gynaecology, 1985, Volume: 92, Issue:7

    Topics: Animals; Antipyrine; Blood Flow Velocity; Blood Proteins; Bupivacaine; Female; Lidocaine; Maternal-Fetal Exchange; Meperidine; Perfusion; Pregnancy; Protein Binding; Rabbits; Umbilical Cord

1985
Hepatic metabolic ability during anaesthesia. Evaluation of antipyrine half-lives and their relation to enflurane metabolism.
    Anaesthesia, 1984, Volume: 39, Issue:7

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Anesthesia, Spinal; Antipyrine; Bupivacaine; Enflurane; Female; Fluorides; Half-Life; Humans; Liver; Male; Middle Aged; Time Factors

1984
Bupivacaine transfer across the human term placenta. A study using the dual perfused human placental model.
    Anesthesiology, 1995, Volume: 82, Issue:2

    Topics: Antipyrine; Bupivacaine; Female; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Maternal-Fetal Exchange; Mepivacaine; Placenta; Pregnancy; Protein Binding

1995
Assessment of automated capillary electrophoresis for therapeutic and diagnostic drug monitoring: determination of bupivacaine in drain fluid and antipyrine in plasma.
    Journal of chromatography. A, 1993, Oct-22, Volume: 652, Issue:2

    Topics: Antipyrine; Body Fluids; Bupivacaine; Chromatography, Gas; Chromatography, High Pressure Liquid; Drug Monitoring; Electrophoresis; Humans; Pleura; Reproducibility of Results

1993
Transfer of lidocaine and bupivacaine across the isolated perfused human placenta.
    Pharmacology & toxicology, 1995, Volume: 77, Issue:2

    Topics: Anesthetics, Local; Antipyrine; Bupivacaine; Female; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Lidocaine; Maternal-Fetal Exchange; Oxygen Consumption; Partial Pressure; Placenta; Pregnancy; Reference Standards

1995
Porcine buccal mucosa as an in vitro model: relative contribution of epithelium and connective tissue as permeability barriers.
    Journal of pharmaceutical sciences, 2009, Volume: 98, Issue:2

    Topics: Administration, Buccal; Animals; Antipyrine; Bupivacaine; Buspirone; Caffeine; Cell Membrane Permeability; Connective Tissue Cells; Diffusion; Diffusion Chambers, Culture; Epithelial Cells; Kinetics; Lipid Bilayers; Models, Biological; Mouth Mucosa; Swine; Technology, Pharmaceutical

2009