Page last updated: 2024-08-21

bufogenin and cinobufagin

bufogenin has been researched along with cinobufagin in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (15.38)18.2507
2000's10 (38.46)29.6817
2010's12 (46.15)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kamano, Y; Nogawa, T; Pettit, GR; Yamashita, A1
Itokawa, H; Kamano, Y; Katsuyama, M; Morita, H; Nogawa, T; Pettit, GR; Saito, K; Segawa, T; Takeya, K; Yamashita, A; Yukita, A1
Enomoto, A; Hayashi, M; Komiyama, K; Rho, MC1
Liu, JH; Sun, Y; Xu, Q; Yu, BY; Zhang, J1
Jiang, RW; Liu, JS; Luo, SL; Tian, HY; Wang, L; Wang, Y; Ye, WC; Zhang, DM; Zhang, XQ1
Chan, K; Hong, Z; Yeung, HW1
Morishita, S; Shimizu, Y1
Bi, K; Guo, T; Song, H; Wang, H; Zhang, R1
Jin, H; Jin, W; Wang, J; Zhou, F1
Chen, Y; Gu, W; Xiang, J; Xu, M1
Guo, D; Ye, M1
Chen, L; Li, Y; Luo, X; Ming, Y; Zhao, Y1
Liren, C; Xingping, L; Yanfang, Z; Yongmin, L; Zongde, Z1
Feng, JF; Liu, D1
Byard, RW; Kostakis, C1
Yao, T; Zheng, B; Zheng, C1
Jin, H; Xia, X; Yan, S; Zhang, W1
Gao, H; Kopp, B; Leitner, A; Wang, Z; Wu, X; Zehl, M1
Cui, J; Liu, J; Lv, L; Ma, XC; Wang, CY; Wei, Q; Xin, XL; Yao, JH1
An, LJ; Bao, YM; Bi, J; Cheng, W; Hao, S; Jiang, B; Liu, JW; Sun, CS; Wang, HS; Zhao, RG1
Gao, B; Li, ZC; Shi, ZN; Xie, RF; Zhou, X1
Chen, L; Guo, C; Song, J; Xing, J; Yang, G; Zeng, A1
Cao, W; Chen, Y; He, JJ; Yuan, L1
Liao, LC; Liu, MD; Wang, W; Xiao, M; Xiong, H; Yan, YY; Ye, Y; Zhao, JH1
Heinbockel, T; Sun, L; Wang, ZJ1
Cao, Y; Cui, K; Pan, H; Wang, L; Wu, J1

Other Studies

26 other study(ies) available for bufogenin and cinobufagin

ArticleYear
Isolation and structure of five new cancer cell growth inhibitory bufadienolides from the Chinese traditional drug Ch'an Su.
    Journal of natural products, 2001, Volume: 64, Issue:9

    Topics: Animals; Antineoplastic Agents; Bufanolides; Bufonidae; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; HL-60 Cells; Humans; KB Cells; Leukemia, Myeloid; Magnetic Resonance Spectroscopy; Medicine, Chinese Traditional; Mice; Molecular Conformation; Molecular Structure; Nasopharyngeal Neoplasms; Skin; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Tumor Cells, Cultured

2001
QSAR evaluation of the Ch'an Su and related bufadienolides against the colchicine-resistant primary liver carcinoma cell line PLC/PRF/5(1).
    Journal of medicinal chemistry, 2002, Dec-05, Volume: 45, Issue:25

    Topics: Antineoplastic Agents; Bufanolides; Colchicine; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Liver Neoplasms; Models, Molecular; Quantitative Structure-Activity Relationship; Tumor Cells, Cultured

2002
Inhibitory effects of bufadienolides on interleukin-6 in MH-60 cells.
    Journal of natural products, 2004, Volume: 67, Issue:12

    Topics: Animals; Bufanolides; Bufo bufo; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Interleukin-6; Mice; Molecular Structure; Stereoisomerism; Tumor Cells, Cultured

2004
Microbial transformation of three bufadienolides by Nocardia sp. and some insight for the cytotoxic structure-activity relationship (SAR).
    Bioorganic & medicinal chemistry letters, 2007, Nov-15, Volume: 17, Issue:22

    Topics: Acetylation; Antineoplastic Agents; Biotransformation; Bufanolides; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Nocardia; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Structure-Activity Relationship

2007
C23 steroids from the venom of Bufo bufo gargarizans.
    Journal of natural products, 2013, Oct-25, Volume: 76, Issue:10

    Topics: Amphibian Venoms; Animals; Antineoplastic Agents; Bufanolides; Bufo bufo; China; Drug Screening Assays, Antitumor; Hep G2 Cells; Humans; Inhibitory Concentration 50; Mice; Mice, Inbred Strains; Molecular Structure; Sodium-Potassium-Exchanging ATPase; Spleen; Structure-Activity Relationship

2013
Simultaneous determination of bufadienolides in the traditional Chinese medicine preparation, liu-shen-wan, by liquid chromatography.
    The Journal of pharmacy and pharmacology, 1992, Volume: 44, Issue:12

    Topics: Bufanolides; Cardiotonic Agents; Chromatography, High Pressure Liquid; Medicine, Chinese Traditional

1992
Metabolism and disposition of kyushin, a drug containing senso (ch'an su).
    The American journal of Chinese medicine, 1996, Volume: 24, Issue:3-4

    Topics: Bufanolides; Cardiotonic Agents; Humans; Male; Medicine, Chinese Traditional

1996
Determination of resibufogenin and cinobufagin in heart-protecting musk pill by HPLC.
    Biomedical chromatography : BMC, 2000, Volume: 14, Issue:2

    Topics: Bufanolides; Calibration; Cardiotonic Agents; Chromatography, High Pressure Liquid; Medicine, Chinese Traditional; Sensitivity and Specificity; Spectrophotometry, Ultraviolet

2000
[Determination of resibufogenin and cinobufagin in venenum Bufonis by HPLC].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1998, Volume: 23, Issue:11

    Topics: Amphibian Venoms; Animals; Bufanolides; Bufo bufo; Bufonidae; Chromatography, High Pressure Liquid; Materia Medica

1998
[Chemical constituents of Bufo Siccus].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1998, Volume: 23, Issue:10

    Topics: Animals; Bufanolides; Bufo bufo; Materia Medica; Molecular Structure

1998
Substrate specificity for the 12beta-hydroxylation of bufadienolides by Alternaria alternata.
    Journal of biotechnology, 2005, May-25, Volume: 117, Issue:3

    Topics: Alternaria; Biotransformation; Bufanolides; Cholenes; Chromatography, High Pressure Liquid; Hydroxylation; Kinetics; Spectrometry, Mass, Electrospray Ionization; Substrate Specificity

2005
Rapid separation and determination of resibufogenin and cinobufagin in toad venom and Liushen tablet by beta-cyclodextrin modified micellar electrokinetic chromatography.
    Journal of pharmaceutical and biomedical analysis, 2006, Apr-11, Volume: 41, Issue:1

    Topics: Amphibian Venoms; Animals; beta-Cyclodextrins; Bufanolides; Chemistry, Pharmaceutical; Chromatography; Electrochemistry; Hydrogen-Ion Concentration; Medicine, Chinese Traditional; Methanol; Models, Chemical; Ranidae; Tablets; Technology, Pharmaceutical

2006
Microemulsion electrokinetic chromatographic determination of bufadienolides in toad venom and in traditional Chinese medicine.
    Analytical and bioanalytical chemistry, 2006, Volume: 384, Issue:5

    Topics: Amphibian Venoms; Animals; Anura; Bufanolides; Capillary Electrochromatography; Emulsions; Hydrogen-Ion Concentration; Medicine, Chinese Traditional; Molecular Conformation; Pharmaceutical Preparations; Reproducibility of Results; Sensitivity and Specificity; Sodium Dodecyl Sulfate; Stereoisomerism; Temperature; Time Factors

2006
[Determination of apparent aqueous solubility and apparent oil-water partition coefficients of three bufadienolides composition].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2008, Volume: 33, Issue:11

    Topics: Bufanolides; Calibration; Hydrogen-Ion Concentration; Logistic Models; Oils; Solubility; Temperature; Water

2008
Sudden death associated with intravenous injection of toad extract.
    Forensic science international, 2009, Jul-01, Volume: 188, Issue:1-3

    Topics: Amphibian Venoms; Animals; Anura; Bufanolides; Bufotenin; Death, Sudden; Forensic Toxicology; Hallucinogens; Humans; Illicit Drugs; Injections, Intravenous; Male; N-Methyl-3,4-methylenedioxyamphetamine; Young Adult

2009
[Study on quality standards for Lingmaoxiang Jiedu pills].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2010, Volume: 35, Issue:3

    Topics: Bufanolides; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Reproducibility of Results

2010
Analysis of the bioactive constituents of ChanSu in rat plasma by high performance liquid chromatography with mass spectrometric detection.
    Journal of pharmaceutical and biomedical analysis, 2010, Nov-02, Volume: 53, Issue:3

    Topics: Animals; Bufanolides; Chromatography, High Pressure Liquid; Male; Medicine, Chinese Traditional; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization

2010
Comparison of toad venoms from different Bufo species by HPLC and LC-DAD-MS/MS.
    Journal of ethnopharmacology, 2010, Sep-15, Volume: 131, Issue:2

    Topics: Amphibian Venoms; Animals; Arginine; Bufanolides; Bufonidae; Chromatography, High Pressure Liquid; Mass Spectrometry

2010
Preparative separation of four major bufadienolides from the Chinese traditional medicine, Chansu, using high-speed counter-current chromatography.
    Natural product communications, 2010, Volume: 5, Issue:7

    Topics: Bufanolides; Chromatography, High Pressure Liquid; Countercurrent Distribution; Drugs, Chinese Herbal; Molecular Structure

2010
Effects of Resibufogenin and Cinobufagin on voltage-gated potassium channels in primary cultures of rat hippocampal neurons.
    Toxicology in vitro : an international journal published in association with BIBRA, 2011, Volume: 25, Issue:8

    Topics: Amphibian Venoms; Animals; Bufanolides; CA1 Region, Hippocampal; Cells, Cultured; Membrane Potentials; Patch-Clamp Techniques; Potassium Channels; Pyramidal Cells; Rats; Rats, Sprague-Dawley

2011
Bufothionine, a possible effective component in cinobufocini injection for hepatocellular carcinoma.
    Journal of ethnopharmacology, 2012, Jun-01, Volume: 141, Issue:2

    Topics: Amphibian Venoms; Antineoplastic Agents; Bufanolides; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Flow Cytometry; G2 Phase Cell Cycle Checkpoints; Humans; Indole Alkaloids; Injections; Liver Neoplasms; Medicine, Chinese Traditional; Quinolinium Compounds; Time Factors

2012
Separation and determination of resibufogenin and cinobufagin in Chansu using reversed-phase liquid chromatography with γ-cyclodextrin as mobile-phase modifier.
    Journal of separation science, 2012, Volume: 35, Issue:15

    Topics: Animals; Bufanolides; Bufonidae; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Cyclodextrins

2012
[Determination of protein binding rates of cinobufagin and resibufogenin with different plasmas by HPLC].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2012, Volume: 47, Issue:9

    Topics: Animals; Blood Proteins; Bufanolides; Chromatography, High Pressure Liquid; Dialysis; Dogs; Humans; Molecular Structure; Protein Binding; Rats; Species Specificity

2012
[Determination of cinobufagin and resibufogenin in liver tissue by HPLC-MS/MS].
    Fa yi xue za zhi, 2013, Volume: 29, Issue:4

    Topics: Bufanolides; Chromatography, High Pressure Liquid; Forensic Toxicology; Humans; Liver; Sensitivity and Specificity; Solvents; Tandem Mass Spectrometry; Tissue Distribution

2013
Resibufogenin and cinobufagin activate central neurons through an ouabain-like action.
    PloS one, 2014, Volume: 9, Issue:11

    Topics: Amphibian Venoms; Animals; Bufanolides; Cardiotonic Agents; Central Nervous System; CHO Cells; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Ion Channel Gating; Membrane Potentials; Mice, Inbred C57BL; NAV1.2 Voltage-Gated Sodium Channel; Neurons; Olfactory Bulb; Ouabain; Patch-Clamp Techniques; Sodium-Potassium-Exchanging ATPase

2014
The impact of multiple climatic and geographic factors on the chemical defences of Asian toads (Bufo gargarizans Cantor).
    Scientific reports, 2019, 11-21, Volume: 9, Issue:1

    Topics: Animals; Bufanolides; Bufo bufo; Geography; Temperature; Toxins, Biological

2019