bufalin and sorafenib

bufalin has been researched along with sorafenib in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (83.33)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Cohen, L; Gao, Y; Gu, K; Li, HX; Meng, ZQ; Wang, P; Xu, LT; Xu, LY; Yang, PY1
Fang, T; Hu, F; Jin, X; Pan, S; Sun, X; Xu, L; Yan, H; Zhai, B; Zhao, D1
Meng, Z; Ning, Z; Wang, H; Xu, L; Zhang, C; Zhu, X1
Chi, H; Meng, Z; Wang, H; Zhang, C2
Cheng, AS; Feng, H; Gao, Y; Huang, L; Jiang, Y; Le, F; Li, M; Sun, X; Yu, DY; Yu, Z; Zhang, X; Zheng, C; Zhou, Z; Zhu, X; Zhuo, Y1

Other Studies

6 other study(ies) available for bufalin and sorafenib

ArticleYear
Bufalin enhances the anti-proliferative effect of sorafenib on human hepatocellular carcinoma cells through downregulation of ERK.
    Molecular biology reports, 2012, Volume: 39, Issue:2

    Topics: Antineoplastic Agents; Benzenesulfonates; Blotting, Western; Bufanolides; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Chromones; Drug Synergism; Gene Expression Regulation, Enzymologic; Humans; Liver Neoplasms; Microscopy, Electron, Transmission; Morpholines; Niacinamide; Phenylurea Compounds; Pyridines; Sorafenib

2012
Bufalin Reverses Resistance to Sorafenib by Inhibiting Akt Activation in Hepatocellular Carcinoma: The Role of Endoplasmic Reticulum Stress.
    PloS one, 2015, Volume: 10, Issue:9

    Topics: Apoptosis; Bufanolides; Carcinoma, Hepatocellular; Cell Proliferation; Drug Resistance, Neoplasm; Endoplasmic Reticulum Stress; Hep G2 Cells; Humans; Liver Neoplasms; Niacinamide; Phenylurea Compounds; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Sorafenib

2015
Bufalin enhances anti-angiogenic effect of sorafenib via AKT/VEGF signaling.
    International journal of oncology, 2016, Volume: 48, Issue:3

    Topics: Angiogenesis Inhibitors; Animals; Aorta; Apoptosis; Bufanolides; Cell Cycle; Cell Movement; Cell Proliferation; Cell Survival; Chick Embryo; Cytokines; Drug Synergism; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Human Umbilical Vein Endothelial Cells; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neovascularization, Pathologic; Niacinamide; Phenylurea Compounds; Proto-Oncogene Proteins c-akt; Random Allocation; Rats; Signal Transduction; Sorafenib; Vascular Endothelial Growth Factor A

2016
Synergistic anti-hepatoma effect of bufalin combined with sorafenib via mediating the tumor vascular microenvironment by targeting mTOR/VEGF signaling.
    International journal of oncology, 2018, Volume: 52, Issue:6

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bufanolides; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cell Survival; Culture Media, Conditioned; Drug Synergism; Gene Expression Regulation, Neoplastic; Human Umbilical Vein Endothelial Cells; Humans; Liver Neoplasms; Mice; Niacinamide; Phenylurea Compounds; Signal Transduction; Sorafenib; TOR Serine-Threonine Kinases; Tumor Microenvironment; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays

2018
Synergistic anticancer effects of bufalin and sorafenib by regulating apoptosis associated proteins.
    Molecular medicine reports, 2018, Volume: 17, Issue:6

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Bufanolides; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Drug Synergism; Humans; Male; Mice; Neoplasms; Niacinamide; Phenylurea Compounds; Sorafenib; Xenograft Model Antitumor Assays

2018
Bufalin inhibits hepatitis B virus-associated hepatocellular carcinoma development through androgen receptor dephosphorylation and cell cycle-related kinase degradation.
    Cellular oncology (Dordrecht), 2020, Volume: 43, Issue:6

    Topics: Animals; beta Catenin; Bufanolides; Carcinogenesis; Carcinoma, Hepatocellular; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase-Activating Kinase; Cyclin-Dependent Kinases; Glycogen Synthase Kinase 3 beta; Hepatitis B virus; Liver Neoplasms; Mice, Nude; Mice, Transgenic; Models, Biological; Phosphorylation; Proteolysis; Receptors, Androgen; Signal Transduction; Sorafenib; Trans-Activators; Viral Regulatory and Accessory Proteins

2020