bucumolol has been researched along with isoproterenol in 2 studies
*Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant. [MeSH]
*Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant. [MeSH]
| Studies (bucumolol) | Trials (bucumolol) | Recent Studies (post-2010) (bucumolol) | Studies (isoproterenol) | Trials (isoproterenol) | Recent Studies (post-2010) (isoproterenol) |
|---|---|---|---|---|---|
| 7 | 0 | 0 | 30,780 | 803 | 2,640 |
| Protein | Taxonomy | bucumolol (IC50) | isoproterenol (IC50) |
|---|---|---|---|
| Beta-2 adrenergic receptor | Homo sapiens (human) | 0.246 | |
| Beta-1 adrenergic receptor | Homo sapiens (human) | 0.333 | |
| Beta-2 adrenergic receptor | Rattus norvegicus (Norway rat) | 0.2125 | |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | 1.77 | |
| Beta-1 adrenergic receptor | Rattus norvegicus (Norway rat) | 0.2125 | |
| Beta-3 adrenergic receptor | Rattus norvegicus (Norway rat) | 0.2125 | |
| Beta-2 adrenergic receptor | Canis lupus familiaris (dog) | 0.6667 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Koike, H; Nakayama, K; Oshima, T | 1 |
| Koike, H; Kumakura, S; Nakayama, K; Oshima, T | 1 |
2 other study(ies) available for bucumolol and isoproterenol
| Article | Year |
|---|---|
Antiarrhythmic activity of dextro- and levo-isomers of 5-methyl-8-(2-hydroxy-3-t-butylamino-propoxy) coumarin hydrocholoride (bucumolol), a beta-adrenergic blocking agent, on aconitine-induced atrial and ouabain-induced ventricular arrhythmias in dogs.
Topics: Aconitine; Aconitum; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Anura; Arrhythmias, Cardiac; Coumarins; Dogs; Female; Guinea Pigs; Heart Atria; Heart Rate; Heart Ventricles; In Vitro Techniques; Isoproterenol; Male; Ouabain; Propanolamines; Propranolol; Quinidine; Refractory Period, Electrophysiological; Stereoisomerism; Stimulation, Chemical; Structure-Activity Relationship | 1979 |
Pharmacology of dl-5-methyl-8-(2-hydroxy-3-t-butylaminopropoxy) coumarin hydrochloride (CS-359), a new beta-adrenergic blocking agent.
Topics: Aconitum; Action Potentials; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Anura; Arrhythmias, Cardiac; Blood Pressure; Cardiovascular System; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electric Stimulation; Guinea Pigs; Heart; In Vitro Techniques; Isoproterenol; Lethal Dose 50; Mice; Ouabain; Propanolamines; Propranolol; Retina; Sciatic Nerve; Stellate Ganglion | 1973 |