bucladesine has been researched along with n-formylmethionine leucyl-phenylalanine in 86 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (27.91) | 18.7374 |
| 1990's | 52 (60.47) | 18.2507 |
| 2000's | 8 (9.30) | 29.6817 |
| 2010's | 2 (2.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hescheler, J; Krautwurst, D; Schultz, G; Seifert, R | 1 |
| Mattera, R; Thévenod, F; Xing, M | 1 |
| Cronstein, BN; Haines, KA; Kolasinski, S; Reibman, J | 1 |
| Bengis-Garber, C; Gruener, N | 2 |
| Richter, J | 1 |
| Heller, DN; Raffin, TA; Schumann, MA; Tanigaki, T | 1 |
| Buschauer, A; Höer, A; Offermanns, S; Schunack, W; Seifert, R | 1 |
| Ervens, J; Schultz, G; Seifert, R | 1 |
| Brown, GE; Lanser, ME; Reed, EB | 1 |
| Laskin, DL; Laskin, JD; Sirak, AA | 1 |
| Akutagawa, H; Kim, KM; Mayumi, M; Mikawa, H; Morita, M; Nambu, M; Ohshima, Y; Uenoyama, Y | 1 |
| Grünbaum, L; Seifert, R; Wenzel-Seifert, K | 1 |
| Downey, GP; Elson, EL; Erzurum, SC; Schwab, B; Worthen, GS; Young, SK | 1 |
| Kasahara, T; Kitagawa, S; Matsushima, K; Saito, M; Takaku, F; Yuo, A | 1 |
| Laskin, DL; Laskin, JD; Robertson, FM; Sirak, AA | 2 |
| Seifert, R; Wenzel-Seifert, K | 2 |
| Beavis, AJ; Laskin, DL; Laskin, JD; O'Connell, SM; Sirak, AA | 1 |
| Chambaut-Guerin, AM; Delbourg, I; Ribier, A; Thomopoulos, P; Ventura, MA | 1 |
| Coats, WD; Navarro, J | 1 |
| Jackowski, S; Rettenmier, CW; Rock, CO | 1 |
| Aviram, A; Rephaeli, A; Shaklai, M | 1 |
| Boulay, F; Brouchon, L; Tardif, M; Vignais, P | 1 |
| Post, TJ; Schulman, ES; Vigderman, RJ | 1 |
| Godfrey, RW; Hoffstein, ST; Jensen, BD; Manzi, RM | 1 |
| Jungblut, P; Schultz, G; Seifert, R | 1 |
| Böhme, E; Schmidt, HH; Seifert, R | 1 |
| Burde, R; Schultz, G; Seifert, R | 1 |
| Nath, J; Rothwell, SW; Wright, DG | 1 |
| Cohen, HJ; Currie, MS; Rao, KM; Weinberg, JB | 1 |
| Wada, Y | 1 |
| Choy, YM; Fung, KP; Kong, SK; Lee, CY | 1 |
| Burde, R; Buschauer, A; Schultz, G; Seifert, R | 1 |
| Heiman, DF; Malech, HL | 1 |
| Kramer, IM; Roos, D; van der Bend, RL; Verhoeven, AJ | 1 |
| Cohen, HJ; Currie, MS; Rao, KM; Ruff, JC | 1 |
| Cohen, HJ; Crawford, J; Currie, MS; Rao, KM | 1 |
| Brandt, SJ; Dougherty, RW; Lapetina, EG; Niedel, JE | 1 |
| Ishitoya, J; Nagai, Y; Takenawa, T | 1 |
| De Togni, P; Della Bianca, V; Di Virgilio, F; Grzeskowiak, M; Vicentini, LM | 1 |
| Parente, JE; Strnad, CF; Wong, K | 1 |
| Ishitoya, J; Kato, H; Takenawa, T | 1 |
| Cabrini, G; De Togni, P; Di Virgilio, F | 1 |
| Columbo, M; Condorelli, M; Marone, G; Soppelsa, L | 1 |
| Smolen, JE | 1 |
| Hamachi, T; Hirata, M; Koga, T | 1 |
| Duque, RE; Fantone, JC; Phan, SH | 1 |
| Musgrave, IF; Schultz, G; Seifert, R | 1 |
| Hallett, MB; Lloyds, D | 1 |
| Garcia-Welsh, A; Laskin, DL; Laskin, JD; Molloy, CJ | 1 |
| Bast, A; Ching, TL; Koelemij, JG | 1 |
| Asahi, M; Minami, Y; Qin, S; Sada, K; Tanaka, Y; Tsubokawa, M; Yamamura, H | 1 |
| Edwards, MJ; Knott, AW; Miller, FN; Nakagawa, K | 1 |
| Costa Rosa, LF; Curi, R; Murphy, C; Newsholme, P | 1 |
| Abe, M; Furuno, T; Hara, N; Hidaka, K; Mitsuyama, T; Takeshige, K; Tanaka, T | 1 |
| Arndts, D; Hammer, R; Hescheler, J; Krautwurst, D; Lösel, W; Schultz, G | 1 |
| Feoktistov, A; Philips, MR; Pillinger, MH; Weissmann, G | 1 |
| Hagelüken, A; Klinker, JF; Offermanns, S; Schwaner, I; Seifert, R | 1 |
| Akutagawa, H; Mayumi, M; Mikawa, H; Morita, M; Nambu, M; Ohshima, Y; Uenoyama, Y | 1 |
| Höer, A; Klinker, JF; Offermanns, S; Schwaner, I; Seifert, R; Wenzel-Seifert, K | 1 |
| Becker, I; Huber, W; Peskar, BM; Schenck, U; Schepp, W; Trautmann, M | 1 |
| Bao, L; Eddy, RL; Gerard, C; Gerard, NP; Shows, TB; Xiao-Ping, H | 1 |
| Cohen, HJ; Gibson-Berry, KL; Whitin, JC | 1 |
| Kessels, GC; Krause, KH; Verhoeven, AJ | 1 |
| Smith, JB; Wollner, A; Wollner, S | 1 |
| Petersen, MM; Steadman, R; Williams, JD | 1 |
| Butcher, EC; Campbell, JJ; Laudanna, C | 1 |
| Alford, JG; Burke, JR; Davern, LB; Gregor, KR; Todderud, G; Tramposch, KM | 1 |
| Anderson, R; Feldman, C; Goolam Mahomed, A; Ramafi, G; Theron, AJ | 1 |
| Capodici, C; Han, G; Pillinger, MH; Weissmann, G | 1 |
| Huang, LJ; Kuo, SC; Raung, SL; Wang, JP | 1 |
| Boulay, F; Christophe, T; Milcent, MD; Rabiet, MJ; Tardif, M | 1 |
| Burke, JR; Davern, LB; Gregor, KR; Owczarczak, LM | 1 |
| Broussas, M; Cornillet-Lefèbvre, P; Nguyen, P; Potron, G | 1 |
| Schulz, I; Sternfeld, L; Thévenod, F | 1 |
| Kanamori, Y; Kanamura, M; Kohno, K; Kozawa, O; Matsuno, H; Niwa, M; Uematsu, T | 1 |
| Belleguic, C; Boichot, E; Corbel, M; Germain, N; Lagente, V | 1 |
| Anderson, R; Steel, HC | 1 |
| Junger, WG; Loomis, WH; Namiki, S; Orlic, T; Shreve, A | 1 |
| Entschladen, F; Hatt, H; Lang, K; Niggemann, B; Zaenker, KS | 1 |
| Allen, JM; Bertrand, C; Jacob, C; Lagente, V; Szilagyi, C | 1 |
| Carrigan, SO; Pink, DB; Stadnyk, AW | 1 |
| Bourgoin, SG; Chouinard, FC; El Azreq, MA; Harbour, D; Pivot-Pajot, C | 1 |
| Chen, J; Cui, Y; Hou, X; Le, Y; Xie, L; Yang, L | 1 |
86 other study(ies) available for bucladesine and n-formylmethionine leucyl-phenylalanine
| Article | Year |
|---|---|
Formyl peptides and ATP stimulate Ca2+ and Na+ inward currents through non-selective cation channels via G-proteins in dibutyryl cyclic AMP-differentiated HL-60 cells. Involvement of Ca2+ and Na+ in the activation of beta-glucuronidase release and superox
Topics: Adenosine Triphosphate; Bucladesine; Calcium; Calcium Channels; Cell Differentiation; Enzyme Activation; Fluorescence; Fura-2; Glucuronidase; GTP-Binding Proteins; Humans; Intracellular Fluid; Ion Channels; Leukemia, Myeloid; Manganese; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Sodium; Sodium Channels; Stimulation, Chemical; Superoxides; Tumor Cells, Cultured | 1992 |
Dual regulation of arachidonic acid release by P2U purinergic receptors in dibutyryl cyclic AMP-differentiated HL60 cells.
Topics: Adenosine Triphosphate; Arachidonic Acid; Bucladesine; Cell Differentiation; Cell Line; Cytidine Triphosphate; Enzyme Activation; Guanosine Triphosphate; Hydrolysis; Inositol Phosphates; Microscopy, Fluorescence; N-Formylmethionine Leucyl-Phenylalanine; Purine Nucleotides; Pyrimidine Nucleotides; Receptors, Purinergic; Second Messenger Systems; Type C Phospholipases | 1992 |
Occupancy of G alpha s-linked receptors uncouples chemoattractant receptors from their stimulus-transduction mechanisms in the neutrophil.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Bucladesine; Cell Membrane; Cyclic AMP; GTP Phosphohydrolases; GTP-Binding Proteins; Humans; Isoquinolines; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphoproteins; Phosphorylation; Piperazines; Protein Kinase Inhibitors; Receptors, Adrenergic, beta; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Purinergic; Signal Transduction; Superoxides | 1992 |
Cross-talk between cAMP and formylmet-leu-phe in human neutrophils: phosphorylation of a 52,000 molecular weight protein.
Topics: Bucladesine; Calcimycin; Calcium; Cyclic AMP; Humans; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Proteins; Second Messenger Systems; Signal Transduction | 1992 |
Effect of adenosine analogues and cAMP-raising agents on TNF-, GM-CSF-, and chemotactic peptide-induced degranulation in single adherent neutrophils.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Blood Proteins; Bucladesine; Cell Adhesion; Cell Degranulation; Chemotactic Factors; Colforsin; Cyclic AMP; Cytochalasin B; Exocytosis; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1992 |
Ca(2+)-dependent and Ca(2+)-independent mechanisms modulate whole-cell cationic currents in human neutrophils.
Topics: Adenine Nucleotides; Bucladesine; Calcimycin; Calcium; Cations; Electrophysiology; In Vitro Techniques; Ion Channel Gating; Ion Channels; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Potassium; Sodium; Tetradecanoylphorbol Acetate | 1992 |
Histamine increases cytosolic Ca2+ in dibutyryl-cAMP-differentiated HL-60 cells via H1 receptors and is an incomplete secretagogue.
Topics: Betahistine; Bucladesine; Calcium; Cations; Cell Differentiation; Cytosol; Glucuronidase; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Humans; Ion Channels; Leukemia, Experimental; Leukemia, Myeloid; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phosphorylation; Receptors, Histamine H1; Secretory Rate; Stimulation, Chemical; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine; Virulence Factors, Bordetella | 1992 |
Differential regulation of chemoattractant-induced superoxide formation in human neutrophils by cell-permeant analogues of cyclic AMP and cyclic GMP.
Topics: Bucladesine; Chemotaxis, Leukocyte; Dibutyryl Cyclic GMP; Humans; In Vitro Techniques; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides | 1991 |
Neutrophil CR3 expression and specific granule exocytosis are controlled by different signal transduction pathways.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Azepines; Bucladesine; Calcimycin; Calcium; Calmodulin; Chlorpromazine; Exocytosis; Gelatinases; Gene Expression Regulation; Humans; In Vitro Techniques; Isoquinolines; Myosin-Light-Chain Kinase; N-Formylmethionine Leucyl-Phenylalanine; Nerve Tissue Proteins; Neutrophils; Pepsin A; Piperazines; Protein Kinase Inhibitors; Receptors, Complement; Receptors, Complement 3b; Signal Transduction; Tetanus Toxin; Up-Regulation | 1991 |
Differentiation of HL-60 myeloid leukaemia cells is associated with a transient block in the G2 phase of the cell cycle.
Topics: Acridine Orange; Bucladesine; Cell Cycle; Cell Differentiation; Cell Line; Demecolcine; G2 Phase; Humans; Hydrogen Peroxide; Hydroxyurea; Kinetics; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Receptors, Formyl Peptide; Receptors, Immunologic; RNA, Neoplasm; Vinblastine | 1991 |
Dibutyryl cyclic AMP induces formyl peptide receptor expression and chemotactic responses in a human eosinophilic cell line, EoL-1.
Topics: Actins; Bucladesine; Butyrates; Butyric Acid; Calcium; Cell Differentiation; Cell Division; Cell Line; Chemotaxis, Leukocyte; Complement C5a; Eosinophils; Humans; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Polymers; Receptors, Formyl Peptide; Receptors, Immunologic; Time Factors | 1991 |
Differential inhibition of human neutrophil activation by cyclosporins A, D, and H. Cyclosporin H is a potent and effective inhibitor of formyl peptide-induced superoxide formation.
Topics: Bucladesine; Calcium; Cell Aggregation; Cell Differentiation; Complement C5a; Cyclosporine; Cyclosporins; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Glucuronidase; Humans; In Vitro Techniques; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Formyl Peptide; Receptors, Immunologic; Superoxides; Time Factors; Tumor Cells, Cultured | 1991 |
Biophysical properties and microfilament assembly in neutrophils: modulation by cyclic AMP.
Topics: 1-Methyl-3-isobutylxanthine; Actin Cytoskeleton; Bucladesine; Cyclic AMP; Dinoprostone; Humans; Kinetics; Microscopy, Fluorescence; Models, Biological; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinases | 1991 |
Stimulation and priming of human neutrophils by interleukin-8: cooperation with tumor necrosis factor and colony-stimulating factors.
Topics: Adult; Alprostadil; Bucladesine; Calcium; Cytoplasm; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Interleukin-8; Kinetics; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Recombinant Proteins; Reference Values; Superoxides; Time Factors; Tumor Necrosis Factor-alpha | 1991 |
Distinct patterns of chemotactic peptide-induced calcium mobilization in differentiated myeloid leukemia cells and peripheral blood neutrophils.
Topics: Biological Transport, Active; Bucladesine; Calcium; Chemotactic Factors; Dose-Response Relationship, Drug; Flow Cytometry; Gallic Acid; Humans; In Vitro Techniques; Leukemia, Myeloid; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Verapamil | 1991 |
Nucleotide-, chemotactic peptide- and phorbol ester-induced exocytosis in HL-60 leukemic cells.
Topics: Bucladesine; Calcium; Cell Differentiation; Cytochalasin B; Exocytosis; Glucuronidase; Humans; Leukemia; N-Formylmethionine Leucyl-Phenylalanine; Nucleotides; Phorbol Esters; Superoxides; Tumor Cells, Cultured | 1990 |
Differentiation of U-937 histiocytic lymphoma cells towards mature neutrophilic granulocytes by dibutyryl cyclic adenosine-3',5'-monophosphate.
Topics: Antibodies, Monoclonal; Antigens, Surface; Biomarkers; Bucladesine; Cell Cycle; Cell Differentiation; Cell Division; Cell Line; Fluorescent Antibody Technique; Humans; Hydrogen Peroxide; Kinetics; Lymphoma, Large B-Cell, Diffuse; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Formyl Peptide; Receptors, Immunologic; Superoxides; Tumor Cells, Cultured | 1990 |
The adhesiveness of monocytic U937 cells is stimulated by pro-inflammatory agents and inhibited by adenosine 3':5'-cyclic monophosphate.
Topics: 2-Chloroadenosine; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Alprostadil; Bucladesine; Calcitriol; Cell Adhesion; Cell Differentiation; Cell Line; Cyclic AMP; Diglycerides; Humans; Kinetics; Leukotriene B4; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Tretinoin | 1990 |
Functional reconstitution of fMet-Leu-Phe receptor in Xenopus laevis oocytes.
Topics: Animals; Bucladesine; Calcium; Cell Differentiation; Cell Line; Female; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Oocytes; Receptors, Formyl Peptide; Receptors, Immunologic; RNA, Neoplasm; Tumor Cells, Cultured; Xenopus laevis | 1990 |
Prostaglandin E2 inhibition of growth in a colony-stimulating factor 1-dependent macrophage cell line.
Topics: Animals; Bucladesine; Cell Division; Cell Line; Cell Survival; Colony-Stimulating Factors; Dinoprostone; DNA Replication; Dose-Response Relationship, Drug; Kinetics; Leukotriene B4; Macrophage Colony-Stimulating Factor; Macrophages; N-Formylmethionine Leucyl-Phenylalanine; Thymidine | 1990 |
The role of increased calcium influx rate in receptor mediated function of differentiating HL-60 cells.
Topics: Bucladesine; Calcium; Cell Differentiation; Cholera Toxin; Concanavalin A; Humans; Kinetics; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Receptors, Formyl Peptide; Receptors, Immunologic; Tretinoin; Tumor Cells, Cultured | 1990 |
Failure of F-Met-Leu-Phe to induce chemotaxis in differentiated promyelocytic (HL-60) leukemia cells.
Topics: Antigens, Surface; Bucladesine; Butyrates; Cell Differentiation; Cell Division; Chemotaxis, Leukocyte; Colforsin; Dinoprostone; Humans; Hydrogen Peroxide; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Tumor Cells, Cultured | 1990 |
The human N-formylpeptide receptor. Characterization of two cDNA isolates and evidence for a new subfamily of G-protein-coupled receptors.
Topics: Amino Acid Sequence; Animals; Base Sequence; Bucladesine; Cell Line; Cell Membrane; Cloning, Molecular; DNA, Neoplasm; Gene Library; GTP-Binding Proteins; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Molecular Sequence Data; Molecular Weight; Multigene Family; N-Formylmethionine Leucyl-Phenylalanine; Protein Conformation; Receptors, Formyl Peptide; Receptors, Immunologic; Restriction Mapping; Sequence Homology, Nucleic Acid; Transfection | 1990 |
Density heterogeneity of human lung mast cells.
Topics: 1-Methyl-3-isobutylxanthine; Bucladesine; Calcimycin; Cell Count; Cell Separation; Histamine; Histamine Release; Humans; Isoproterenol; Lung; Masoprocol; Mast Cells; N-Formylmethionine Leucyl-Phenylalanine; p-Methoxy-N-methylphenethylamine; Prostaglandin D2; Prostaglandins D | 1988 |
FMLP-induced arachidonic acid release, phospholipid metabolism, and calcium mobilization in human monocytes. Regulation by cyclic AMP.
Topics: 1-Methyl-3-isobutylxanthine; Arachidonic Acid; Arachidonic Acids; Bucladesine; Calcimycin; Calcium; Cells, Cultured; Chromatography, Thin Layer; Cyclic AMP; Cytosol; Humans; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Phospholipids | 1988 |
Differential expression of cytosolic activation factors for NADPH oxidase in HL-60 leukemic cells.
Topics: Arachidonic Acid; Arachidonic Acids; Bucladesine; Calcimycin; Cell Differentiation; Cell Line; Cytosol; Dimethyl Sulfoxide; Enzyme Activation; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Hexachlorocyclohexane; Humans; Kinetics; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Superoxides; Tetradecanoylphorbol Acetate; Thionucleotides | 1989 |
Formation and release of nitric oxide from human neutrophils and HL-60 cells induced by a chemotactic peptide, platelet activating factor and leukotriene B4.
Topics: Bucladesine; Calcitriol; Canavanine; Cell Line; Humans; In Vitro Techniques; Kinetics; Leukemia, Promyelocytic, Acute; Leukotriene B4; Luminescence; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitric Oxide; Platelet Activating Factor | 1989 |
Activation of NADPH oxidase by purine and pyrimidine nucleotides involves G proteins and is potentiated by chemotactic peptides.
Topics: Adenosine Triphosphate; Bucladesine; Enzyme Activation; GTP-Binding Proteins; Humans; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Superoxides; Tumor Cells, Cultured; Uracil Nucleotides; Uridine Triphosphate | 1989 |
Interactions of cytoplasmic granules with microtubules in human neutrophils.
Topics: Adenosine Triphosphatases; Bucladesine; Cell Fractionation; Cell Movement; Cell-Free System; Cytoplasmic Granules; Humans; Immunoblotting; In Vitro Techniques; Kinesins; Microscopy, Electron; Microtubules; N-Formylmethionine Leucyl-Phenylalanine; Nerve Tissue Proteins; Neutrophils | 1989 |
Chemotactic peptide receptor-cytoskeletal interactions and functional correlations in differentiated HL-60 cells and human polymorphonuclear leukocytes.
Topics: Bucladesine; Cell Differentiation; Cholera Toxin; Cytoskeleton; Interferon-gamma; Leukemia, Myeloid; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Formyl Peptide; Receptors, Immunologic; Superoxides; Tretinoin; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Virulence Factors, Bordetella | 1989 |
Cyclic AMP inhibits chemotactic-peptide-induced but not Ca2+-ionophore- or tetradecanoylphorbol-acetate-induced enzyme secretion in guinea pig neutrophils.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alprostadil; Animals; Bucladesine; Calcimycin; Cyclic AMP; Guinea Pigs; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Signal Transduction; Tetradecanoylphorbol Acetate | 1989 |
cAMP activates Na+/H+ antiporter in murine macrophages.
Topics: Amiloride; Animals; Bucladesine; Carrier Proteins; Cell Line; Cholera Toxin; Cyclic AMP; Hematopoietic Stem Cells; Hydrogen-Ion Concentration; Kinetics; Macrophages; Mice; Mice, Inbred BALB C; N-Formylmethionine Leucyl-Phenylalanine; Sodium-Hydrogen Exchangers | 1989 |
Histamine inhibits activation of human neutrophils and HL-60 leukemic cells via H2-receptors.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Alprostadil; Bucladesine; Cell Aggregation; Cyclic AMP; Exocytosis; Glucuronidase; Histamine; Humans; Leukemia; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Receptors, Histamine H2; Superoxides; Tumor Cells, Cultured | 1989 |
Swainsonine induced modification of N-linked oligosaccharides on human phagocytic cell formyl peptide chemotactic receptors.
Topics: Alkaloids; Bucladesine; Cell Differentiation; Cycloheximide; Electrophoresis, Polyacrylamide Gel; Glycoside Hydrolases; Humans; Leukemia, Myeloid; Lymphoma, Large B-Cell, Diffuse; Macrophages; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Oligosaccharides; Phagocytes; Receptors, Formyl Peptide; Receptors, Immunologic; Swainsonine; Tumor Cells, Cultured | 1987 |
The 47-kDa protein involved in the NADPH:O2 oxidoreductase activity of human neutrophils is phosphorylated by cyclic AMP-dependent protein kinase without induction of a respiratory burst.
Topics: Bucladesine; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Granulomatous Disease, Chronic; Humans; Isoelectric Focusing; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Oxygen Consumption; Phosphoproteins; Phosphorylation; Protein Kinases | 1988 |
Lack of correlation between induction of chemotactic peptide receptors and stimulus-induced actin polymerization in HL-60 cells treated with dibutyryl cyclic adenosine monophosphate or retinoic acid.
Topics: Actins; Bucladesine; Cell Cycle; Cell Differentiation; Humans; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Polymers; Receptors, Formyl Peptide; Receptors, Immunologic; Tretinoin; Tumor Cells, Cultured | 1988 |
Actin depolymerization and inhibition of capping induced by pentoxifylline in human lymphocytes and neutrophils.
Topics: Actins; Bucladesine; Humans; Immunologic Capping; Lymphocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentoxifylline; Pertussis Toxin; Polymers; Theobromine; Virulence Factors, Bordetella | 1988 |
Pertussis toxin inhibits chemotactic peptide-stimulated generation of inositol phosphates and lysosomal enzyme secretion in human leukemic (HL-60) cells.
Topics: Animals; Bacterial Toxins; Bordetella pertussis; Bucladesine; Calcium; Cell Line; GTP-Binding Proteins; Humans; Leukemia, Experimental; Lysosomes; N-Formylmethionine Leucyl-Phenylalanine; Pertussis Toxin; Phosphatidylinositols; Receptors, Formyl Peptide; Receptors, Immunologic; Type C Phospholipases; Virulence Factors, Bordetella | 1985 |
Inhibitory effect of prostaglandin E2, forskolin, and dibutyryl cAMP on arachidonic acid release and inositol phospholipid metabolism in guinea pig neutrophils.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Bucladesine; Calcimycin; Catechols; Colforsin; Dinoprostone; Fatty Acids, Nonesterified; Guinea Pigs; Lysosomes; Masoprocol; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositols; Prostaglandins E; Pyrazoles; Superoxides | 1986 |
Cyclic AMP inhibition of phosphoinositide turnover in human neutrophils.
Topics: Alprostadil; Bucladesine; Cyclic AMP; Diglycerides; Humans; Intracellular Fluid; Membrane Lipids; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositols; Theophylline; Type C Phospholipases | 1986 |
Use of fluoride ion as a probe for the guanine nucleotide-binding protein involved in the phosphoinositide-dependent neutrophil transduction pathway.
Topics: Bucladesine; GTP-Binding Proteins; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phosphatidylinositols; Protein Kinase C; Sodium Fluoride; Virulence Factors, Bordetella | 1986 |
Inhibition of inositol phospholipids metabolism and calcium mobilization by cyclic AMP-increasing agents and phorbol ester in neutrophils.
Topics: Animals; Bucladesine; Calcium; Cyclic AMP; Dinoprostone; Ethers; Female; Guinea Pigs; Ionomycin; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phorbol Esters; Phosphatidylinositols; Prostaglandins E; Protein Kinases | 1986 |
Cyclic AMP inhibition of fMet-Leu-Phe-dependent metabolic responses in human neutrophils is not due to its effects on cytosolic Ca2+.
Topics: Bucladesine; Calcium; Cyclic AMP; Cytosol; Glucuronidase; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Protein Binding; Vitamin B 12 | 1984 |
The mechanism of basophil histamine release induced by pepstatin A.
Topics: 1-Methyl-3-isobutylxanthine; Adolescent; Adult; Alprostadil; Basophils; Bucladesine; Cross Reactions; Desensitization, Immunologic; Dose-Response Relationship, Immunologic; Histamine Release; Humans; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Oligopeptides; Pepstatins; Prostaglandins E | 1984 |
The fluorescence response of chlortetracycline-loaded human neutrophils is modulated by prostaglandin E1, but not by cyclic nucleotides.
Topics: Alprostadil; Bucladesine; Chlortetracycline; Cyclic AMP; Cyclic GMP; Dibutyryl Cyclic GMP; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Prostaglandins E; Spectrometry, Fluorescence | 1983 |
Effect of cAMP-elevating drugs on Ca2+ efflux and actin polymerization in peritoneal macrophages stimulated with N-formyl chemotactic peptide.
Topics: Actins; Animals; Brain; Bucladesine; Calcium; Calmodulin; Cyclic AMP; Dogs; Guinea Pigs; Isoproterenol; Kinetics; Macromolecular Substances; Macrophage Activation; Macrophages; N-Formylmethionine Leucyl-Phenylalanine; Papaverine; Theophylline | 1984 |
Prostaglandin modulation of N-formylmethionylleucylphenylalanine-induced transmembrane potential changes in rat neutrophils.
Topics: Alprostadil; Animals; Bucladesine; Cyclic AMP; Epoprostenol; Female; Isoproterenol; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Prostaglandins E; Prostaglandins E, Synthetic; Rats; Tetradecanoylphorbol Acetate | 1984 |
Maitotoxin activates cation channels distinct from the receptor-activated non-selective cation channels of HL-60 cells.
Topics: Bucladesine; Cadmium; Calcium; Cations; Fluorescent Dyes; Fura-2; Gadolinium; Humans; Imidazoles; Ion Channels; Manganese; Marine Toxins; N-Formylmethionine Leucyl-Phenylalanine; Oxocins; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Cells, Cultured | 1994 |
Protein expression and development of oxidase "priming" in maturing HL60 cells.
Topics: Bucladesine; Cell Differentiation; Granulocytes; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidoreductases; Protein Serine-Threonine Kinases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Substance P; Superoxides; Tumor Cells, Cultured | 1994 |
Alterations in expression of p56lck during myeloid differentiation of LSTRA cells.
Topics: Antigens, Differentiation; Bucladesine; Carboxylesterase; Carboxylic Ester Hydrolases; Cell Cycle; Cell Differentiation; Cholecalciferol; Enzyme Induction; Granulocytes; Hematopoietic Stem Cells; Histocompatibility Antigens Class II; Humans; Leukemia; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Macrophages; N-Formylmethionine Leucyl-Phenylalanine; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine | 1994 |
The effect of histamine on the oxidative burst of HL60 cells before and after exposure to reactive oxygen species.
Topics: Bucladesine; Calcium; Cell Differentiation; Histamine; Humans; Hydrogen-Ion Concentration; Leukemia, Promyelocytic, Acute; Mast Cells; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Reactive Oxygen Species; Respiratory Burst; Superoxides; Tumor Cells, Cultured | 1995 |
Cyclic AMP-elevating agents negatively regulate the activation of p72syk in N-formyl-methionyl-leucyl-phenylalanine receptor signaling.
Topics: Amino Acid Sequence; Animals; Bucladesine; Colforsin; Cyclic AMP; Dinoprostone; Enzyme Activation; Enzyme Precursors; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein-Tyrosine Kinases; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Signal Transduction; Swine; Syk Kinase | 1995 |
Pentoxifylline inhibits FMLP-induced macromolecular leakage.
Topics: Animals; Bucladesine; Capillary Permeability; Cell Adhesion; Leukocytes; Macromolecular Substances; Male; Microcirculation; N-Formylmethionine Leucyl-Phenylalanine; Pentoxifylline; Rats; Rats, Sprague-Dawley; Serum Albumin, Bovine | 1995 |
Effect of adrenaline and phorbol myristate acetate or bacterial lipopolysaccharide on stimulation of pathways of macrophage glucose, glutamine and O2 metabolism. Evidence for cyclic AMP-dependent protein kinase mediated inhibition of glucose-6-phosphate d
Topics: Animals; Bucladesine; Cell Membrane Permeability; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Digitonin; Epinephrine; Glucose; Glucosephosphate Dehydrogenase; Glutamine; Glycerol; Hydrogen Peroxide; In Vitro Techniques; Interferon-gamma; Kinetics; Lipopolysaccharides; Macrophages, Peritoneal; Malate Dehydrogenase; Male; Mycobacterium bovis; N-Formylmethionine Leucyl-Phenylalanine; NADP; Oxygen Consumption; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate | 1995 |
An inhibitor of cyclic AMP-dependent protein kinase enhances the superoxide production of human neutrophils stimulated by N-formyl-methionyl-leucyl-phenylalanine.
Topics: Bucladesine; Calcium; Cell Membrane Permeability; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Isoquinolines; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Respiratory Burst; Signal Transduction; Sodium Dodecyl Sulfate; Sulfonamides; Superoxides; Tetradecanoylphorbol Acetate | 1995 |
Novel potent inhibitor of receptor-activated nonselective cation currents in HL-60 cells.
Topics: Acetamides; Adenosine Triphosphate; Bucladesine; Cations; Cell Differentiation; Electrophysiology; Humans; Ion Channels; Isoquinolines; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tumor Cells, Cultured | 1993 |
Crosstalk in signal transduction via EP receptors: prostaglandin E1 inhibits chemoattractant-induced mitogen-activated protein kinase activity in human neutrophils.
Topics: Adenosine Triphosphate; Alprostadil; Bucladesine; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; GTP-Binding Proteins; Humans; In Vitro Techniques; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Prostaglandin E; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate | 1995 |
Differential activation of dibutyryl cAMP-differentiated HL-60 human leukemia cells by chemoattractants.
Topics: Bucladesine; Calcium; Cell Differentiation; Complement C5a; Enzyme Activation; GTP Phosphohydrolases; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Hydrolysis; Leukemia; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Signal Transduction; Tumor Cells, Cultured | 1994 |
Inhibitory effects of azelastine hydrochloride on Ca2+ influx, actin polymerization and release of eosinophil cationic protein of an eosinophilic leukaemia cell line EoL-1.
Topics: Actins; Blood Proteins; Bucladesine; Calcimycin; Calcium-Transporting ATPases; Cell Differentiation; Culture Media; Dose-Response Relationship, Drug; Eosinophil Granule Proteins; Eosinophils; Humans; Hypersensitivity; Immunoglobulin G; Inflammation; Leukemia, Eosinophilic, Acute; Leukemia, T-Cell; Lipoxygenase Inhibitors; N-Formylmethionine Leucyl-Phenylalanine; Phthalazines; Platelet Activating Factor; Polymers; Ribonucleases; Tumor Cells, Cultured | 1993 |
Lipopeptides activate Gi-proteins in dibutyryl cyclic AMP-differentiated HL-60 cells.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Bucladesine; Cell Differentiation; Cell Line; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Lipoproteins; Membrane Proteins; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Superoxides; Time Factors; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1993 |
Leukotriene B4 and C4 production in isolated rat gastric mucosal cells.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Bucladesine; Calcimycin; Cell Separation; Colforsin; Diglycerides; Female; Gastric Mucosa; Histamine; In Vitro Techniques; Interleukin-1; Interleukin-2; Kinetics; Leukotriene B4; Leukotriene C4; Lipoxygenase Inhibitors; N-Formylmethionine Leucyl-Phenylalanine; Pentagastrin; Phenothiazines; Platelet Activating Factor; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate | 1993 |
Human chemotaxis receptor genes cluster at 19q13.3-13.4. Characterization of the human C5a receptor gene.
Topics: Animals; Antisense Elements (Genetics); Base Sequence; Bucladesine; Cell Differentiation; Chloramphenicol O-Acetyltransferase; Chromosome Banding; Chromosomes, Human, Pair 19; Complement C5a; DNA, Neoplasm; Exons; Humans; In Situ Hybridization; Leukemia, Basophilic, Acute; Lymphoma; Molecular Sequence Data; Multigene Family; N-Formylmethionine Leucyl-Phenylalanine; Neuroblastoma; Oligodeoxyribonucleotides; Oligonucleotides, Antisense; Polymerase Chain Reaction; Promoter Regions, Genetic; Rats; Receptor, Anaphylatoxin C5a; Receptors, Complement; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Neurotransmitter; Receptors, Tachykinin; Recombinant Proteins; Restriction Mapping; Transfection; Tumor Cells, Cultured | 1993 |
Modulation of the respiratory burst in human neutrophils by isoproterenol and dibutyryl cyclic AMP.
Topics: Bucladesine; Humans; Isoproterenol; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Protein Kinases; Respiratory Burst; Superoxides | 1993 |
Cyclosporin H is a potent and selective formyl peptide receptor antagonist. Comparison with N-t-butoxycarbonyl-L-phenylalanyl-L-leucyl-L-phenylalanyl-L- leucyl-L-phenylalanine and cyclosporins A, B, C, D, and E.
Topics: Amino Acid Sequence; Bucladesine; Cell Differentiation; Cell Membrane; Cyclosporine; Cyclosporins; Glucuronidase; Humans; In Vitro Techniques; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Oligopeptides; Receptors, Formyl Peptide; Receptors, Immunologic; Superoxides; Tumor Cells, Cultured | 1993 |
Protein kinase C activity is not involved in N-formylmethionyl-leucyl-phenylalanine-induced phospholipase D activation in human neutrophils, but is essential for concomitant NADPH oxidase activation: studies with a staurosporine analogue with improved sel
Topics: Alkaloids; Bucladesine; Enzyme Activation; Humans; In Vitro Techniques; Isoquinolines; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Phospholipase D; Protein Kinase C; Staurosporine; Sulfonamides; Superoxides; Tetradecanoylphorbol Acetate | 1993 |
Acting via A2 receptors, adenosine inhibits the upregulation of Mac-1 (Cd11b/CD18) expression on FMLP-stimulated neutrophils.
Topics: Adenosine; Adult; Bucladesine; Cells, Cultured; Colchicine; Humans; Macrophage-1 Antigen; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Purinergic; Up-Regulation; Vinblastine | 1993 |
Protein kinase A downregulates the phosphorylation of p47 phox in human neutrophils: a possible pathway for inhibition of the respiratory burst.
Topics: Bucladesine; Carbazoles; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Enzyme Inhibitors; Humans; Indoles; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophil Activation; Neutrophils; Phosphoproteins; Phosphorylation; Pyrroles; Respiratory Burst; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate | 1996 |
Human neutrophil secondary granule exocytosis is independent of protein kinase activation and is modified by calmodulin activity.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenylyl Cyclases; Bucladesine; Calmodulin; Cytoplasmic Granules; Dinoprostone; Enzyme Activation; Enzyme Inhibitors; Exocytosis; Genistein; Humans; Isoflavones; Lysosomes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Vanadates | 1996 |
Elevation of intracellular cAMP inhibits RhoA activation and integrin-dependent leukocyte adhesion induced by chemoattractants.
Topics: Adult; Amino Acid Sequence; Animals; Bucladesine; Cell Adhesion; Cell Line; Chemotactic Factors; Cyclic AMP; GTP-Binding Proteins; Humans; Integrins; Interleukin-8; Leukocytes; Mice; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Signal Transduction | 1997 |
Phosphorylation and calcium influx are not sufficient for the activation of cytosolic phospholipase A2 in U937 cells: requirement for a Gi alpha-type G-protein.
Topics: Acyltransferases; Adenylate Cyclase Toxin; Antibodies, Monoclonal; Arachidonic Acids; Blotting, Western; Bucladesine; Calcium; Cell Differentiation; Cyclic AMP; Cytosol; Electroporation; Enzyme Activation; Enzyme Inhibitors; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Inositol 1,4,5-Trisphosphate; Intercellular Signaling Peptides and Proteins; Ionomycin; Ionophores; N-Formylmethionine Leucyl-Phenylalanine; Peptides; Pertussis Toxin; Phospholipases A; Phospholipases A2; Phosphorylation; Tumor Cells, Cultured; Type C Phospholipases; Virulence Factors, Bordetella; Wasp Venoms | 1997 |
Effect of rolipram and dibutyryl cyclic AMP on resequestration of cytosolic calcium in FMLP-activated human neutrophils.
Topics: Adrenergic beta-Agonists; Adult; Albuterol; Bucladesine; Calcium; Calcium Radioisotopes; Cytosol; Fluorescent Dyes; Fura-2; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphodiesterase Inhibitors; Pyrrolidinones; Rolipram; Superoxides; Theophylline | 1998 |
Inflammation and anti-inflammation: gating of cell/cell adhesion at the level of mitogen-activated protein kinases.
Topics: Alprostadil; Arachidonic Acid; Bucladesine; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Cell Adhesion; Cell Aggregation; Cyclic GMP; Dibutyryl Cyclic GMP; Enzyme Activation; Humans; In Vitro Techniques; Inflammation; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Salicylates; Salicylic Acid; Virulence Factors, Bordetella | 1997 |
Involvement of cyclic AMP generation in the inhibition of respiratory burst by 2-phenyl-4-quinolone (YT-1) in rat neutrophils.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Bucladesine; Calcium; Carbazoles; Cardiotonic Agents; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cytosol; Indoles; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Protein Kinase C; Pyrroles; Quinolones; Rats; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate | 1998 |
Isolation and characterization of a variant HL60 cell line defective in the activation of the NADPH oxidase by phorbol myristate acetate.
Topics: Androstadienes; Bucladesine; Calcium-Calmodulin-Dependent Protein Kinases; Cell Differentiation; Dimethyl Sulfoxide; Enzyme Activation; Enzyme Inhibitors; Flavonoids; GTP-Binding Proteins; HL-60 Cells; Humans; Isoenzymes; MAP Kinase Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Models, Biological; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neoplasm Proteins; Oxidation-Reduction; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; rac GTP-Binding Proteins; Recombinant Fusion Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection; Virulence Factors, Bordetella; Wortmannin | 1998 |
Differentiation of U937 cells enables a phospholipase D-dependent pathway of cytosolic phospholipase A2 activation.
Topics: Adenosine Triphosphate; Arachidonic Acid; Bucladesine; Cell Differentiation; Cytosol; Diglycerides; Electroporation; Ethanol; Glycerophospholipids; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Ionomycin; Ionophores; N-Formylmethionine Leucyl-Phenylalanine; Phospholipase D; Phospholipases A; Phospholipases A2; Signal Transduction; Solvents; U937 Cells | 1999 |
Inhibition of fMLP-triggered respiratory burst of human monocytes by adenosine: involvement of A3 adenosine receptor.
Topics: Adenosine; Bucladesine; Calcium; Carbazoles; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytochalasin B; Enzyme Activation; Enzyme Inhibitors; Flow Cytometry; Humans; Indoles; Luminescent Measurements; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Oxygen Consumption; Pyrroles; Receptor, Adenosine A3; Receptors, Purinergic P1; Respiratory Burst; RNA, Messenger; Second Messenger Systems; Theobromine; Xanthines | 1999 |
fMLP-induced arachidonic acid release in db-cAMP-differentiated HL-60 cells is independent of phosphatidylinositol-4, 5-bisphosphate-specific phospholipase C activation and cytosolic phospholipase A(2) activation.
Topics: 1-Butanol; Arachidonic Acid; Arachidonic Acids; Bacterial Proteins; Bacterial Toxins; Bridged-Ring Compounds; Bucladesine; Calcimycin; Calcium; Cell Membrane; Cytosol; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Estrenes; HL-60 Cells; Humans; Indoles; Ionophores; Models, Biological; N-Formylmethionine Leucyl-Phenylalanine; Norbornanes; Phosphatidylinositol 4,5-Diphosphate; Phosphodiesterase Inhibitors; Phosphoinositide Phospholipase C; Phospholipase D; Phospholipases A; Phosphoric Diester Hydrolases; Phosphorylation; Precipitin Tests; Pyrrolidinones; Thiocarbamates; Thiones; Time Factors; Type C Phospholipases | 2000 |
Usefulness of grading of neutrophil aggregate size by laser-light scattering technique for characterizing stimulatory and inhibitory effects of agents on aggregation.
Topics: Androstadienes; Bucladesine; Cell Aggregation; Cell Count; Cytochalasin B; Dinoprostone; Enzyme Activators; Enzyme Inhibitors; Humans; Lasers; Light; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Particle Size; Phorbol Esters; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Scattering, Radiation; Tetradecanoylphorbol Acetate; Wortmannin | 2000 |
Effects of PDE4 inhibitors on lipopolysaccharide-induced priming of superoxide anion production from human mononuclear cells.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Benzamides; Bucladesine; Cells, Cultured; Cyclic Nucleotide Phosphodiesterases, Type 4; Humans; Interleukin-10; Leukocytes, Mononuclear; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Phosphodiesterase Inhibitors; Pyridines; Rolipram; Superoxides; Time Factors | 2001 |
Dissociation of the PAF-receptor from NADPH oxidase and adenylate cyclase in human neutrophils results in accelerated influx and delayed clearance of cytosolic calcium.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Adenylyl Cyclases; Bucladesine; Calcium; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Cytosol; Homeostasis; Humans; In Vitro Techniques; Leukocyte Elastase; Luminescent Measurements; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophil Activation; Neutrophils; Phenethylamines; Phosphodiesterase Inhibitors; Platelet Activating Factor; Platelet Membrane Glycoproteins; Purinergic P1 Receptor Agonists; Radioimmunoassay; Receptor, Adenosine A2A; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Rolipram; Spectrometry, Fluorescence; Superoxides | 2002 |
Hypertonicity increases cAMP in PMN and blocks oxidative burst by PKA-dependent and -independent mechanisms.
Topics: Adenylyl Cyclase Inhibitors; Bucladesine; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Hypertonic Solutions; MAP Kinase Signaling System; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphodiesterase Inhibitors; Respiratory Burst; Signal Transduction; Superoxides | 2002 |
A novel function for chemokines: downregulation of neutrophil migration.
Topics: Bucladesine; Calcium; Cell Adhesion; Chemotaxis, Leukocyte; Down-Regulation; Enzyme Inhibitors; Humans; Interleukin-8; Microscopy, Confocal; Microscopy, Video; N-Formylmethionine Leucyl-Phenylalanine; Naphthalenes; Neutrophils; Signal Transduction; Surface Plasmon Resonance; Tyrphostins | 2003 |
Role of PDE4 in superoxide anion generation through p44/42MAPK regulation: a cAMP and a PKA-independent mechanism.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Bronchoalveolar Lavage Fluid; Bucladesine; CREB-Binding Protein; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclohexanecarboxylic Acids; Flavonoids; Gene Expression Regulation, Enzymologic; Imidazoles; Lipopolysaccharides; Macrophages; Mitogen-Activated Protein Kinases; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitriles; Nuclear Proteins; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-raf; Pyridines; Rats; Rats, Wistar; Reactive Oxygen Species; Rolipram; Superoxides; Trans-Activators | 2004 |
Neutrophil transepithelial migration in response to the chemoattractant fMLP but not C5a is phospholipase D-dependent and related to the use of CD11b/CD18.
Topics: 1-Butanol; Bucladesine; CD11b Antigen; CD18 Antigens; Cell Differentiation; Cell Movement; Chemotactic Factors; Chemotaxis; Complement C5a; Epithelial Cells; Epitopes; HL-60 Cells; Humans; Macrophage-1 Antigen; Models, Immunological; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidic Acids; Phospholipase D; Up-Regulation | 2007 |
Characterisation of degranulation and phagocytic capacity of a human neutrophilic cellular model, PLB-985 cells.
Topics: Bucladesine; Calcium Signaling; Cell Degranulation; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Dimethylformamide; Granulocytes; Humans; Microscopy, Electron; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phagocytosis; Receptors, Formyl Peptide; Receptors, IgG; Receptors, Lipoxin | 2010 |
Sesamin inhibits bacterial formylpeptide-induced inflammatory responses in a murine air-pouch model and in THP-1 human monocytes.
Topics: Animals; Anti-Inflammatory Agents; Bacteria; Basophils; Bucladesine; Calcium; Cell Line; Cell Line, Tumor; Chemotaxis, Leukocyte; Dioxoles; Dose-Response Relationship, Drug; Humans; Inflammation; Leukemia; Leukemic Infiltration; Lignans; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Models, Animal; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; NF-kappa B; Phosphorylation; Phytotherapy; Plant Extracts; Rats; Receptors, Formyl Peptide; Sesamum; Signal Transduction | 2010 |