bucladesine and h 89
bucladesine has been researched along with h 89 in 124 studies
Research
Studies (124)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 50 (40.32) | 18.2507 |
| 2000's | 53 (42.74) | 29.6817 |
| 2010's | 20 (16.13) | 24.3611 |
| 2020's | 1 (0.81) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Hidaka, H; Kanda, K; Matsui, N; Miyamoto, N; Seo, H | 1 |
| Iwanaga, M; Sano, M | 1 |
| Chijiwa, T; Hagiwara, M; Hayashi, K; Hidaka, H; Inoue, T; Mishima, A; Naito, K; Sano, M; Toshioka, T | 1 |
| Bubis, M; Zisapel, N | 1 |
| Allen, JM; Balbi, D | 1 |
| Bailey, JL; Connors, SA; Kopf, GS; Leclerc, P; Moore, GD; Olds-Clarke, P; Pan, D; Visconti, PE | 1 |
| Linde, C; Quast, U | 1 |
| Alvaro, D; Bini, A; Capocaccia, L; Della Guardia, P; Furfaro, S; Gigliozzi, A; La Rosa, T; Piat, C | 1 |
| Deleu, L; Faisst, S; Kherrouche, Z; Perros, M; Rommelaere, J; Spruyt, N; Vanacker, JM | 1 |
| Childs, GV; Kuryshev, YA; Ritchie, AK | 1 |
| Abe, M; Furuno, T; Hara, N; Hidaka, K; Mitsuyama, T; Takeshige, K; Tanaka, T | 1 |
| Lei, ZM; Lin, J; Rao, CV; Shi, QJ | 1 |
| Chan, KF; Loh, TT; Lok, CN | 1 |
| Geertsma, MF; Nibbering, PH; van Furth, R; Zomerdijk, TP | 1 |
| Hirai, H; Ikeuchi, Y; Okada, Y | 1 |
| Katagiri, H; Kurokawa, K; Nakao, A; Oka, Y; Takemoto, F; Uchida, S | 1 |
| Fujimura, S; Kato, N; Miya, T; Sato, K; Tagawa, M; Takahashi, K | 1 |
| Boniece, IR; Maiese, K; Skurat, K; Wagner, JA | 1 |
| Kessels, GC; Krause, KH; Verhoeven, AJ | 1 |
| Muroi, M; Suzuki, T | 1 |
| Ikeda, K; Takasaka, T; Wu, D | 1 |
| Mathupala, SP; Perdersen, PL; Rempel, A | 1 |
| Nishikawa, T; Omura, M; Sasano, H; Suematsu, S | 1 |
| Telfer, WH; Wang, Y | 1 |
| Chiu, CT; Fan, LW; Tsao, HL; Yang, C; Yu, SM | 1 |
| Higuchi, K; Kominami, S; Takemori, S; Yamazaki, T | 1 |
| Hirose, H; Hisanaga, S; Honma, N; Kishimoto, T; Srsen, V; Uchida, A | 1 |
| Nicolaï, S; Slegers, H; Van Mechelen, E; Willems, J; Zwijsen, A | 1 |
| Kohjitani, A; Obara, H; Okada, S; Shirakawa, J | 1 |
| Kimura, M; Ogihara, M | 1 |
| Belosludtsev, YY; Falck, JR; Lai, PS; Shen, SY; Wong, PY | 1 |
| Ariga, T; Nakamura, M; Seki, T; Uno, S | 1 |
| Furuno, T; Hara, N; Hidaka, K; Mitsuyama, T; Tanaka, T | 1 |
| Kranias, EG; Liu, Y; Schneider, MF | 1 |
| Kumar, CK; Ortiz, A; Said, HM; Yanagawa, N | 1 |
| Kaida, T; Kozawa, O; Suzuki, A; Tokuda, H; Uematsu, T | 1 |
| Hirai, A; Moroo, I; Saito, J; Saito, Y; Tanaka, T; Tatsuno, I; Uchida, D | 1 |
| Dallegri, F; Dapino, P; Gonella, R; Ottonello, L; Sacchetti, C | 1 |
| Hersh, LB; Shimojo, M; Wu, D | 1 |
| Aiello, LP; King, GL; Takagi, H | 1 |
| Braiman, A; Priel, Z; Zagoory, O | 1 |
| Abe, K; Izumi, F; Terao, T; Toyohira, Y; Ueno, S; Uezono, Y; Yanagihara, N; Yoshimura, R | 1 |
| Inada, H; Onaya, T; Shindo, H; Tawata, M | 1 |
| Kimura, J; Matsuoka, I; Nakanishi, H; Ohkubo, S; Ono, T | 1 |
| Cantore, ML; Castilla, R; Passeron, S | 1 |
| Goto, S; Hamasaki, T; Nishi, T; Okamura, A; Ushio, Y | 1 |
| Gineitis, A; Savickiene, J; Stigbrand, T | 1 |
| Aunis, D; Eto, T; Izumi, F; Kitamura, K; Kobayashi, H; Masumoto, K; Minami, SI; Niina, H; Wada, A; Yamamoto, R; Yanagita, T | 1 |
| Martinez, JR; Zhang, GH | 1 |
| Izumi, F; Kato, H; Nakashima, Y; Oishi, Y; Okazaki, M; Osajima, A; Suda, T; Tamura, M; Tanaka, H; Uezono, Y | 1 |
| Braun, KW; Griswold, MD; Kim, KH; Tribley, WA | 1 |
| Garde, J; Roldan, ER | 1 |
| Chang, HS; Chung, IY; Jeon, KW; Kim, YH; Park, CS | 1 |
| Hashimoto, F; Kanaoka, K; Kato, Y; Kobayashi, K; Kobayashi, Y; Nakashima, T; Sakai, H; Shibata, M | 1 |
| Burgess, GM; Davis, CL; Smith, JA | 1 |
| Aouani, A; Fayet, G; Hovsepian, S; Lombardo, D; Samih, N | 1 |
| Andréani, M; Antonio, V; Béréziat, G; Brouillet, A; Couturier, C; Raymondjean, M | 1 |
| Botana, LM; de la Rosa, LA; Vieytes, MR; Vilariño, N | 1 |
| Imai, Y; Ito, S; Katsu, K; Nakahari, T; Ohnishi, A; Shimamoto, C | 1 |
| Harayama, H; Kato, S; Miyake, M | 1 |
| Avila, J; Diaz-Nido, J; Lim, F; Sanchez, S; Sayas, CL; Wandosell, F | 1 |
| Asakura, M; Asanuma, H; Fukushima, T; Hori, M; Kitakaze, M; Kuzuya, T; Liao, Y; Mori, H; Node, K; Ogai, A; Ogita, H; Papst, PJ; Sakata, Y; Sanada, S; Shinozaki, Y; Takashima, S; Terada, N; Yamada, J | 1 |
| Söder, O; Sultana, T; Svechnikov, KV | 1 |
| Black , SA; Danaher, RJ; Jacob, RJ; Miller, CS; Savells-Arb, AD | 1 |
| Beckmann, JD; Kai, M; Keeton, TP; Stewart, A | 1 |
| Kabashima, T; Kawaguchi, T; Takenoshita, M; Uyeda, K | 1 |
| Arima, N; Hamada, T; Kimura, S; Murata, Y; Nomaguchi, M; Sasaguri, Y; Tanimoto, A; Xu, H | 1 |
| Ho, J; Lau, HK | 1 |
| Kanematsu, M; Sato, A; Takaoki, M; Yoshimura, K | 1 |
| de Lamirande, E; Gagnon, C; Thundathil, J | 1 |
| Gunter, TE; O'Keefe, RJ; Puzas, JE; Rosier, RN; Schwarz, EM; Zuscik, MJ | 1 |
| Bergoc, R; Cricco, G; Darvas, Z; Falus, A; Fitzsimons, C; Hegyesi, H; Kovács, P; Lázár-Molnár, E; Martin, G; Pállinger, E; Rivera, ES; Tóth, S | 1 |
| Dohovics, R; Hermann, A; Janáky, R; Oja, SS; Saransaari, P; Varga, V | 1 |
| Cho, S; Choe, Y; Kim, G; Kim, K; Park, J | 1 |
| Meyers, SA; Pommer, AC; Rutllant, J | 1 |
| Chosa, E; Eto, T; Hamada, H; Kitamura, K; Kuwasako, K; Tajima, N; Yanagita, T | 1 |
| Barnier, JV; Castell, X; Cheviron, N; Diebler, MF | 1 |
| Danner, RL; Wang, S; Wesley, RA; Zhang, J | 1 |
| Pacheco, MA; Pastoor, TE; Wecker, L | 1 |
| Chaves, MM; Costa, DC; Lima e Silva, FC; Medina, LO; Nogueira-Machado, JA | 1 |
| Doi, SQ; Lagranha, C; Puggina, E; Sellitti, DF | 1 |
| Potashner, SJ; Suneja, SK; Zhang, J | 1 |
| Fischer, JW; Meyer-Kirchrath, J; Nüsing, RM; Sarbia, M; Schrör, K; Sussmann, M | 1 |
| Hara, S; Kunimoto, M; Takanaga, H; Yamasaki, C; Yoshitake, T | 1 |
| Hyun, JW; Jung, SH; Kim, HS; Woo, MS | 1 |
| Itoh, M; Kakita, A; Miura, Y; Oiso, Y; Ono, Y; Suzuki, A | 1 |
| Abe, R; Harada, Y; Hayashi, T; Kubo, M; Matsushita, H; Ono, Y; Tokoyoda, K; Tsujikawa, K; Yamamoto, H | 1 |
| Kyoi, T; Noda, K; Oka, M; Ukai, Y | 1 |
| Jimenez-Feltstrom, J; Lundquist, I; Salehi, A | 1 |
| Bretschneider, E; Censarek, P; Fischer, JW; Meyer-Kirchrath, J; Pape, R; Rabausch, K; Sarbia, M; Schrör, K; Weber, AA | 1 |
| Iijima, R; Ishida, A; Kobayashi, A; Maeda, M | 1 |
| Chen, SD; Fan, GH; Qi, C; Wang, G; Zhou, HY | 1 |
| Fuchsel, L; Goldstein, BJ; Hough, K; Mahadev, K; Motoshima, H; Ouedraogo, R; Scalia, R; Wu, X; Xu, SQ | 1 |
| Toll, L; Waleh, N; Zaveri, NT | 1 |
| Chatterjee, BP; Chatterjee, U; Saja, K; Sudhakaran, PR | 1 |
| Atreja, SK; Roy, SC | 1 |
| Jo, Y; Manna, PR; Stocco, DM | 1 |
| Nishikawa, T; Omura, M; Suematsu, S | 1 |
| Tanaka, M; Watanabe, Y; Yoshimoto, K | 1 |
| Nogowski, L; Szkudelska, K; Szkudelski, T | 1 |
| Chang, YS; Huang, WT; Lee, TL; Li, CJ; Weng, CF; Wu, PJ | 1 |
| Fujita-Yoshigaki, J; Guo, MY; Matsuki-Fukushima, M; Narita, T; Qi, B; Satoh, K; Sugiya, H | 1 |
| Desiniotis, A; Eder, IE; Klocker, H; Schäfer, G | 1 |
| Liu, K; Liu, R; Mori, S; Nishibori, M; Takahashi, HK; Wake, H; Yoshino, T; Zhang, J | 1 |
| Avni, D; Meijler, MM; Philosoph, A; Zor, T | 1 |
| Buehrer, B; Collins, S; Kumar, N; Pi, J; Yehuda-Shnaidman, E | 1 |
| Chin, TY; Chueh, SH; Huang, WP; Kao, CH; Ma, KH; Wang, HY | 1 |
| Simeone, TA; White, HS; Wilcox, KS | 1 |
| Azami, K; Beyer, C; Ghadiri, T; Gholizadeh, S; Hosseini-Zare, MS; Mobasseri, M; Salehi, F; Seyedi, SY; Sharifzadeh, M | 1 |
| Chen, D; Cooke, HJ; Hao, Q; Hou, H; Huang, Y; Li, L; Shi, Q; Sun, Q; Yi, Q; Zhang, Y | 1 |
| Chen, X; Li, Y; Qi, Z; Szeto, C; Tang, M; Wang, F; Zhang, H; Zhang, X | 1 |
| Fu, J; Koide, SS; Miao, S; Song, W; Wang, L; Zong, S | 1 |
| Amini, E; Ghadiri, T; Mohammadi, M; Nassireslami, E; Nikbin, P; Noorbakhsh, F; Payandemehr, B; Sharifzadeh, M; Vakilzadeh, G | 1 |
| Fabbri, E; Franzellitti, S | 1 |
| Hossein, S; Hosseini-Zare, MS; Nassireslami, E; Payandemehr, B; Salehi, F; Seyedi, SY; Sharifzadeh, M; Yazdi, BB | 1 |
| Cong, B; Jia, X; Li, H; Liu, W; Ma, C; Wen, D; Yang, S; Yu, F; Zhang, X | 1 |
| Aguirre, A; Angulo-Rojo, C; López-Bayghen, E; Manning-Cela, R; Ortega, A | 1 |
| Cuezva, JM; Del Arco, A; García-Bermúdez, J; Nuevo-Tapioles, C; Sánchez-Aragó, M; Soldevilla, B | 1 |
| Atreja, SK; Naresh, S | 1 |
| Cao, L; Huang, J; Ji, L; Jiang, Q; Li, H; Liu, M; Mao, K; Wei, J; Wei, N; Wu, J; Xie, W; Yang, S; Yang, Z; Zhu, L | 1 |
| Chen, F; Lin, J; Ning, SF; Sun, X; Tan, JH; Wang, HL; Xiao, B; Zhu, S | 1 |
| Amelinia, F; Fanoudi, S; Hashemzaei, M; Najafi, S; Nasiri, AA; Sanati, M; Shamshirgaran, F; Tabrizian, K | 1 |
| Adornetto, A; Arcone, R; Grimaldi, M; Masullo, M; Pagliara, V; Parafati, M; White, MC | 1 |
| Galvão, I; Jardim, BLO; Lima, KM; Moreira, IZ; Negreiros-Lima, GL; Pinho, V; Sousa, LP; Sugimoto, MA; Teixeira, LCR; Teixeira, MM; Vago, JP | 1 |
Other Studies
124 other study(ies) available for bucladesine and h 89
| Article | Year |
|---|---|
A 3',5'-cyclic adenosine monophosphate-dependent pathway is responsible for a rapid increase in c-fos messenger ribonucleic acid by adrenocorticotropin.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Bucladesine; Cells, Cultured; Corticosterone; Cyclic AMP; Cycloheximide; Gene Expression; Genes, fos; Isoquinolines; Kinetics; Male; Potassium; Protein Kinase Inhibitors; Protein Kinases; Rats; Rats, Inbred Strains; RNA, Messenger; Sulfonamides; Tetradecanoylphorbol Acetate | 1992 |
Requirement for specific protein kinase activities during the rapid redistribution of F-actin that precedes the outgrowth of neurites in PC12D cells.
Topics: Actins; Animals; Bucladesine; Carbazoles; Colchicine; Cytochalasin B; Cytoskeleton; Epidermal Growth Factor; Fibroblast Growth Factor 2; Indole Alkaloids; Isoquinolines; Nerve Growth Factors; Neurons; Protein Kinases; Rats; Sulfonamides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Inhibition of forskolin-induced neurite outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide (H-89), of PC12D pheochromocytoma
Topics: Adrenal Gland Neoplasms; Animals; Axons; Bucladesine; Cell Line; Colforsin; Isoquinolines; Kinetics; Neoplasm Proteins; Nerve Growth Factors; Pheochromocytoma; Phosphorylation; Protein Kinase Inhibitors; Sulfonamides | 1990 |
Modulation by melatonin of protein secretion from melanoma cells: is cAMP involved?
Topics: Animals; Bucladesine; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Isoquinolines; Melanoma, Experimental; Melatonin; Mice; Protein Biosynthesis; Proteins; Sulfonamides; Tumor Cells, Cultured | 1995 |
Role of protein kinase C in mediating NGF effect on neuropeptide Y expression in PC12 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Base Sequence; Binding Sites; Blotting, Northern; Bucladesine; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Gene Expression; Isoquinolines; Kinetics; Molecular Sequence Data; Naphthalenes; Nerve Growth Factors; Neuropeptide Y; Oligodeoxyribonucleotides; PC12 Cells; Piperazines; Polycyclic Compounds; Promoter Regions, Genetic; Protein Kinase C; RNA, Messenger; Sulfonamides; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1994 |
Capacitation of mouse spermatozoa. II. Protein tyrosine phosphorylation and capacitation are regulated by a cAMP-dependent pathway.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Bucladesine; Calcium; Cell Membrane; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Fertilization in Vitro; Immunoblotting; Isoquinolines; Male; Mice; Phosphorylation; Protein Kinase Inhibitors; Sodium Bicarbonate; Sperm Capacitation; Spermatozoa; Sulfonamides; Tyrosine | 1995 |
Potentiation of P1075-induced K+ channel opening by stimulation of adenylate cyclase in rat isolated aorta.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Aorta; Binding, Competitive; Bucladesine; Colforsin; Cyclic AMP-Dependent Protein Kinases; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Guanidines; In Vitro Techniques; Isoquinolines; Isotope Labeling; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Phosphodiesterase Inhibitors; Potassium Channels; Pyridines; Rats; Rats, Sprague-Dawley; Rubidium; Sulfonamides; Vasodilator Agents | 1995 |
Effect of glucagon on intracellular pH regulation in isolated rat hepatocyte couplets.
Topics: Animals; Antiporters; Bicarbonates; Bile; Bucladesine; Cells, Cultured; Chloride-Bicarbonate Antiporters; Chlorides; Cholagogues and Choleretics; Colchicine; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Glucagon; Hydrogen-Ion Concentration; Intracellular Fluid; Isoquinolines; Liver; Male; Nitrobenzoates; Rats; Rats, Wistar; Sodium; Sodium-Hydrogen Exchangers; Sulfonamides; Tetradecanoylphorbol Acetate; Thionucleotides | 1995 |
Upstream CREs participate in the basal activity of minute virus of mice promoter P4 and in its stimulation in ras-transformed cells.
Topics: Alkaloids; Animals; Base Sequence; Bucladesine; Cell Line; Cell Line, Transformed; Cell Nucleus; Cyclic AMP-Dependent Protein Kinases; DNA, Viral; Gene Expression Regulation, Viral; Genes, ras; Isoquinolines; Kinetics; Minute Virus of Mice; Molecular Sequence Data; Nucleic Acid Conformation; Plasmids; Promoter Regions, Genetic; Rats; Rats, Inbred F344; Regulatory Sequences, Nucleic Acid; Staurosporine; Sulfonamides; TATA Box; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic; Viral Nonstructural Proteins | 1995 |
Corticotropin-releasing hormone stimulation of Ca2+ entry in corticotropes is partially dependent on protein kinase A.
Topics: Animals; Bucladesine; Calcium; Cells, Cultured; Colforsin; Corticotropin-Releasing Hormone; Cyclic AMP-Dependent Protein Kinases; Electrophysiology; Isoquinolines; Male; Membrane Potentials; Pituitary Gland, Anterior; Rats; Rats, Sprague-Dawley; Sulfonamides | 1995 |
An inhibitor of cyclic AMP-dependent protein kinase enhances the superoxide production of human neutrophils stimulated by N-formyl-methionyl-leucyl-phenylalanine.
Topics: Bucladesine; Calcium; Cell Membrane Permeability; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Isoquinolines; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Respiratory Burst; Signal Transduction; Sodium Dodecyl Sulfate; Sulfonamides; Superoxides; Tetradecanoylphorbol Acetate | 1995 |
Novel role of human chorionic gonadotropin in differentiation of human cytotrophoblasts.
Topics: Blotting, Northern; Bucladesine; Cadherins; Cell Aggregation; Cell Differentiation; Cell Membrane; Cells, Cultured; Chorionic Gonadotropin; Female; Follicle Stimulating Hormone; Glycoprotein Hormones, alpha Subunit; Humans; Immunohistochemistry; Isoquinolines; Naphthalenes; Phenols; Placenta; Polycyclic Compounds; Pregnancy; Protein Kinase Inhibitors; Receptors, LH; RNA; RNA, Messenger; Sulfonamides; Transcription, Genetic; Trophoblasts | 1993 |
Effects of protein kinase modulators on transferrin receptor expression in human leukaemic HL-60 cells.
Topics: Alkaloids; Bucladesine; Cell Division; Cell Line; Cyclic AMP-Dependent Protein Kinases; DNA, Neoplasm; Enzyme Activation; Gene Expression; Humans; Indoles; Isoquinolines; Leukemia, Promyelocytic, Acute; Maleimides; Protein Kinase C; Protein Kinases; Receptors, Transferrin; RNA, Messenger; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Thymidine; Tumor Cells, Cultured | 1995 |
Pulmonary surfactant inhibits monocyte bactericidal functions by altering activation of protein kinase A and C.
Topics: Bucladesine; Calcium; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Humans; Immunity, Innate; Isoquinolines; Monocytes; Protein Kinase C; Protein Kinase Inhibitors; Pulmonary Surfactants; Reactive Oxygen Species; Staphylococcus aureus; Sulfonamides | 1994 |
The contribution of PKA to the excitatory mechanism of adenosine in guinea pig superior colliculus slices.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Animals; Bucladesine; Culture Media; Cyclic AMP-Dependent Protein Kinases; Guinea Pigs; In Vitro Techniques; Isoquinolines; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Sulfonamides; Superior Colliculi; Synaptic Transmission | 1994 |
Desensitization of endothelin-1 binding by vasopressin via a cAMP-mediated pathway in rat CCD.
Topics: Amino Acid Sequence; Animals; Arginine Vasopressin; Binding Sites; Bucladesine; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Endothelins; GTP-Binding Proteins; In Vitro Techniques; Isoquinolines; Kidney Cortex; Kidney Tubules, Collecting; Kinetics; Male; Molecular Sequence Data; Muscle, Smooth, Vascular; Rats; Rats, Wistar; Receptors, Endothelin; Stereoisomerism; Sulfonamides | 1995 |
Prostaglandin E2/parathyroid hormone-induced suppression of alkaline phosphatase activity is mediated by protein kinase C.
Topics: Alkaline Phosphatase; Alkaloids; Animals; Bucladesine; Calcimycin; Cyclic AMP; Cycloheximide; Dinoprostone; Isoquinolines; Osteoblasts; Osteosarcoma; Parathyroid Hormone; Protein Kinase C; Rats; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Protein kinases modulate the sensitivity of hippocampal neurons to nitric oxide toxicity and anoxia.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Bucladesine; Cell Death; Cell Hypoxia; Cells, Cultured; Dibutyryl Cyclic GMP; Hippocampus; Isoquinolines; Nerve Tissue Proteins; Nitric Oxide; Phorbol Esters; Piperazines; Protein Kinase Inhibitors; Protein Kinases; Rats; Rats, Sprague-Dawley; Signal Transduction; Sphingosine; Staurosporine; Sulfonamides | 1993 |
Protein kinase C activity is not involved in N-formylmethionyl-leucyl-phenylalanine-induced phospholipase D activation in human neutrophils, but is essential for concomitant NADPH oxidase activation: studies with a staurosporine analogue with improved sel
Topics: Alkaloids; Bucladesine; Enzyme Activation; Humans; In Vitro Techniques; Isoquinolines; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Phospholipase D; Protein Kinase C; Staurosporine; Sulfonamides; Superoxides; Tetradecanoylphorbol Acetate | 1993 |
Role of protein kinase A in LPS-induced activation of NF-kappa B proteins of a mouse macrophage-like cell line, J774.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amino Acid Sequence; Animals; Base Sequence; Bucladesine; Cholera Toxin; Colforsin; Consensus Sequence; Cyclic AMP; Dinoprostone; Female; Gene Expression Regulation, Neoplastic; Isoquinolines; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Neoplasm Proteins; NF-kappa B; Phosphorylation; Piperazines; Protein Kinases; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Transcription Factor RelB; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured | 1993 |
Cellular mechanisms in activation of Na-K-Cl cotransport in nasal gland acinar cells of guinea pigs.
Topics: Acetylcholine; Alkaloids; Animals; Benzophenanthridines; Biological Transport; Bucladesine; Bumetanide; Calcium; Calmodulin; Carrier Proteins; Charybdotoxin; Cholinergic Fibers; Cyclic AMP; Cyclic GMP; Enzyme Inhibitors; Exocrine Glands; Furosemide; Guinea Pigs; Ionomycin; Ionophores; Isoquinolines; Nasal Cavity; Phenanthridines; Protein Kinase Inhibitors; Protein Kinases; Second Messenger Systems; Signal Transduction; Sodium; Sodium-Potassium-Chloride Symporters; Sulfonamides; Tetradecanoylphorbol Acetate; Trifluoperazine; Vasoactive Intestinal Peptide | 1995 |
Glucose catabolism in cancer cells: regulation of the Type II hexokinase promoter by glucose and cyclic AMP.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Colforsin; Cyclic AMP; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Glucose; Hexokinase; Hexoses; Isoquinolines; Liver Neoplasms, Experimental; Mannoheptulose; Promoter Regions, Genetic; Rats; Signal Transduction; Sulfonamides; Transfection; Tumor Cells, Cultured | 1996 |
Regulation of expression of the steroidogenic acute regulatory (StAR) protein by ACTH in bovine adrenal fasciculata cells.
Topics: Adrenocorticotropic Hormone; Animals; Bucladesine; Calcimycin; Cattle; Cells, Cultured; Colforsin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation; Hydrocortisone; Immunohistochemistry; Isoquinolines; Kinetics; Naphthalenes; Phosphoproteins; Quinazolines; Sulfonamides; Tetradecanoylphorbol Acetate; Zona Fasciculata | 1996 |
Cyclic nucleotide-induced termination of vitellogenin uptake by Hyalophora cecropia follicles.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Bucladesine; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Drug Synergism; Enzyme Activation; Female; Isoquinolines; Moths; Nucleotides, Cyclic; Oviducts; Phosphodiesterase Inhibitors; Sulfonamides; Vitellogenins | 1996 |
Regulation of 5-hydroxytryptamine-induced calcium mobilization by cAMP-elevating agents in cultured canine tracheal smooth muscle cells.
Topics: Adenine; Aluminum Compounds; Animals; Bucladesine; Calcium; Cholera Toxin; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Diterpenes; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Fluorides; GTP-Binding Proteins; Isoquinolines; Male; Muscle, Smooth; PC12 Cells; Rats; Serotonin; Serotonin Antagonists; Sulfonamides; Trachea | 1996 |
15-lipoxygenase metabolite(s) of arachidonic acid mediates adrenocorticotropin action in bovine adrenal steroidogenesis.
Topics: Animals; Arachidonate 15-Lipoxygenase; Arachidonic Acids; Benzoquinones; Bucladesine; Cattle; Cells, Cultured; Cosyntropin; Cyclic AMP; Dihydrotestosterone; Enzyme Inhibitors; Indomethacin; Isoquinolines; Kinetics; Leukotrienes; Lipid Peroxides; Lipoxygenase Inhibitors; Masoprocol; Pregnenolone; Sulfonamides; Tetrahydronaphthalenes; Zona Fasciculata; Zona Reticularis | 1996 |
Two types of apoptotic cell death of rat central nervous system-derived neuroblastoma B50 and B104 cells: apoptosis induced during proliferation and after differentiation.
Topics: Animals; Apoptosis; Bucladesine; Cell Differentiation; Cell Division; Cell Line; Central Nervous System Neoplasms; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; DNA, Neoplasm; Enzyme Inhibitors; Isoquinolines; Kinetics; Neurites; Neuroblastoma; Neurons; Rats; Sulfonamides; Time Factors; Tumor Cells, Cultured | 1996 |
Cyclic AMP-induced differentiation increases the synthesis of extracellular superoxide dismutase in rat C6 glioma.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bucladesine; Cell Differentiation; Cell Line; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Extracellular Space; Glial Fibrillary Acidic Protein; Glioma; Isoquinolines; Kinetics; Rats; RNA, Messenger; Sulfonamides; Superoxide Dismutase; Transcription, Genetic | 1996 |
The relaxing effect of ketamine on isolated rabbit lower esophageal sphincter.
Topics: Adenylyl Cyclases; Anesthetics, Dissociative; Animals; Atropine; Bucladesine; Calcium; Cyclic AMP; Cyclic GMP; Dibutyryl Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Esophagogastric Junction; In Vitro Techniques; Isoquinolines; Ketamine; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Niacin; Protein Kinase Inhibitors; Rabbits; Sulfonamides | 1997 |
Density-dependent proliferation of adult rat hepatocytes in primary culture induced by epidermal growth factor is potentiated by cAMP-elevating agents.
Topics: Adrenergic beta-Agonists; Animals; Bucladesine; Cell Count; Cell Division; Cells, Cultured; DNA; Epidermal Growth Factor; Genistein; Isoflavones; Isoquinolines; Liver; Male; Metaproterenol; Rats; Rats, Wistar; Signal Transduction; Sulfonamides | 1997 |
Post-receptor signal transduction and regulation of 14(R),15(S)-epoxyeicosatrienoic acid (14,15-EET) binding in U-937 cells.
Topics: 8,11,14-Eicosatrienoic Acid; Binding Sites; Bucladesine; Cell Adhesion; Cell Line; Cholera Toxin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Humans; Isoquinolines; Monocytes; Pertussis Toxin; Protein Binding; Receptors, Cell Surface; Signal Transduction; Stereoisomerism; Sulfonamides; Virulence Factors, Bordetella | 1997 |
Induction of tissue-type plasminogen activator (tPA) and type-1 plasminogen activator inhibitor (PAI-1) as early growth responses in rat hepatocytes in primary culture.
Topics: Animals; Bucladesine; Cells, Cultured; Cycloheximide; Enzyme Inhibitors; Gene Expression; Isoquinolines; Liver; Male; Plasminogen Activator Inhibitor 1; Protein Synthesis Inhibitors; Rats; Rats, Wistar; RNA, Messenger; Sulfonamides; Tissue Plasminogen Activator | 1997 |
The role of nitric oxide in human pulmonary artery endothelial cell injury mediated by neutrophils.
Topics: Benzoates; Bucladesine; Coculture Techniques; Cyclic AMP-Dependent Protein Kinases; Endothelium, Vascular; Humans; Imidazoles; Isoquinolines; L-Lactate Dehydrogenase; Monocytes; Neutrophils; Nitric Oxide; Pulmonary Artery; Sulfonamides | 1997 |
Regulation of Ca2+ handling by phosphorylation status in mouse fast- and slow-twitch skeletal muscle fibers.
Topics: Action Potentials; Adenosine Triphosphatases; Animals; Bucladesine; Calcium; Calcium-Binding Proteins; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Isoquinolines; Mice; Mice, Knockout; Muscle Fibers, Fast-Twitch; Muscle Fibers, Slow-Twitch; Muscle, Skeletal; Phosphorylation; Sulfonamides | 1997 |
Mechanism and regulation of riboflavin uptake by human renal proximal tubule epithelial cell line HK-2.
Topics: 1-Methyl-3-isobutylxanthine; Biological Transport; Bucladesine; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Epithelial Cells; Genistein; Humans; Isoquinolines; Kidney Tubules, Proximal; Kinetics; Nitriles; Protein Kinase C; Protein-Tyrosine Kinases; Riboflavin; Sulfonamides; Temperature; Tyrphostins | 1998 |
Interleukin-6 synthesis induced by prostaglandin E2: cross-talk regulation by protein kinase C.
Topics: 3T3 Cells; Animals; Bucladesine; Calcimycin; Calcium; Chelating Agents; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Interleukin-6; Ionophores; Isoquinolines; Mice; Naphthalenes; Protein Kinase C; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Sulfonamides | 1998 |
Pituitary adenylate cyclase activating polypeptide (PACAP) stimulates mitogen-activated protein kinase (MAPK) in cultured rat astrocytes.
Topics: Animals; Astrocytes; Bucladesine; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Isoquinolines; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Neuropeptides; Neurotransmitter Agents; p38 Mitogen-Activated Protein Kinases; Pituitary Adenylate Cyclase-Activating Polypeptide; Pregnancy; Protein Kinase C; Protein Kinases; Rats; Rats, Sprague-Dawley; Sulfonamides | 1998 |
Prostaglandin E2 inhibits apoptosis in human neutrophilic polymorphonuclear leukocytes: role of intracellular cyclic AMP levels.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adult; Apoptosis; Bucladesine; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 4; Dinoprostone; Flow Cytometry; Humans; Intracellular Fluid; Isoquinolines; Male; Neutrophils; Phosphodiesterase Inhibitors; Respiratory Burst; Second Messenger Systems; Sulfonamides | 1998 |
The cholinergic gene locus is coordinately regulated by protein kinase A II in PC12 cells.
Topics: Animals; Bucladesine; Carrier Proteins; Choline O-Acetyltransferase; Chromosome Mapping; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Gene Expression Regulation, Enzymologic; Isoquinolines; Membrane Transport Proteins; Mutation; PC12 Cells; Polymerase Chain Reaction; Rats; RNA, Messenger; Sulfonamides; Vesicular Acetylcholine Transport Proteins; Vesicular Transport Proteins | 1998 |
Hypoxia upregulates glucose transport activity through an adenosine-mediated increase of GLUT1 expression in retinal capillary endothelial cells.
Topics: Adenosine; Animals; Biological Transport; Bucladesine; Capillaries; Cattle; Cell Hypoxia; Cells, Cultured; Cyclic AMP; Deoxyglucose; Endothelium, Vascular; Gene Expression Regulation; Glucose Transporter Type 1; Isoquinolines; Kinetics; Monosaccharide Transport Proteins; Purinergic P1 Receptor Agonists; Retinal Vessels; RNA, Messenger; Sulfonamides; Time Factors; Transcription, Genetic | 1998 |
PKA induces Ca2+ release and enhances ciliary beat frequency in a Ca2+-dependent and -independent manner.
Topics: Animals; Bucladesine; Calcium; Cells, Cultured; Cilia; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Egtazic Acid; Enzyme Inhibitors; Esophagus; Estrenes; Homeostasis; Isoquinolines; Kinetics; Mucous Membrane; Pyrrolidinones; Rana ridibunda; Sulfonamides; Thapsigargin; Type C Phospholipases | 1998 |
Carbamazepine-induced up-regulation of voltage-dependent Na+ channels in bovine adrenal medullary cells in culture.
Topics: Adrenal Medulla; Animals; Anticonvulsants; Bucladesine; Carbachol; Carbamazepine; Catecholamines; Cattle; Cells, Cultured; Cycloheximide; Dactinomycin; Ion Channel Gating; Ion Transport; Isoquinolines; Potassium; Sodium Channel Agonists; Sulfonamides; Up-Regulation; Veratridine | 1998 |
cAMP regulates nitric oxide production and ouabain sensitive Na+, K+-ATPase activity in SH-SY5Y human neuroblastoma cells.
Topics: Bucladesine; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Enzyme Inhibitors; Epoprostenol; Humans; Isoquinolines; Kinetics; Neuroblastoma; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitrites; Ouabain; Sodium-Potassium-Exchanging ATPase; Sulfonamides; Tumor Cells, Cultured | 1998 |
Effects of YT-146 [2-(1-octynyl) adenosine], an adenosine A2A receptor agonist, on cAMP production and noradrenaline release in PC12 cells.
Topics: Adenosine; Adenosine Triphosphate; Alkynes; Animals; Bucladesine; Calcimycin; Calcium; Carbachol; Cholinergic Agonists; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Ionophores; Isoquinolines; Membrane Potentials; Norepinephrine; PC12 Cells; Potassium Chloride; Purinergic P1 Receptor Agonists; Rats; Receptor, Adenosine A2A; Sulfonamides; Thionucleotides; Tritium; Vasodilator Agents | 1998 |
N-acetyl-D-glucosamine induces germination in Candida albicans through a mechanism sensitive to inhibitors of cAMP-dependent protein kinase.
Topics: Acetylglucosamine; Bucladesine; Candida albicans; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Glucagon; Isoquinolines; Morphogenesis; Sulfonamides | 1998 |
Overexpression of striatal enriched phosphatase (STEP) promotes the neurite outgrowth induced by a cAMP analogue in PC12 cells.
Topics: Animals; Bucladesine; Corpus Striatum; Cyclic AMP; DNA Probes; Enzyme Inhibitors; Fluorescent Antibody Technique; Gene Expression Regulation, Enzymologic; Isoquinolines; Neurites; PC12 Cells; Plasmids; Protein Tyrosine Phosphatases; Rats; Signal Transduction; Sulfonamides; Transfection | 1999 |
Modulation of apoptosis of proliferating and differentiating HL-60 cells by protein kinase inhibitors: suppression of PKC or PKA differently affects cell differentiation and apoptosis.
Topics: Apoptosis; Bucladesine; Cell Cycle; Cell Differentiation; Cell Division; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; HL-60 Cells; Humans; Indoles; Isoquinolines; Maleimides; Naphthalenes; Protein Kinase C; Sulfonamides; Tretinoin | 1999 |
Cyclic AMP-dependent synthesis and release of adrenomedullin and proadrenomedullin N-terminal 20 peptide in cultured bovine adrenal chromaffin cells.
Topics: Adrenal Medulla; Adrenomedullin; Animals; Bucladesine; Cattle; Cells, Cultured; Chromaffin Cells; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Gene Expression Regulation; Isoquinolines; Kinetics; Peptide Fragments; Peptides; Protein Precursors; Proteins; RNA, Messenger; Sulfonamides; Transcription, Genetic | 1999 |
Effects of forksolin, dibutyryl cAMP and H89 on Ca2+ mobilization in submandibular salivary cells of newborn rats.
Topics: Acetylcholine; Age Factors; Animals; Animals, Newborn; Bucladesine; Calcium; Calcium Signaling; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Female; Inositol 1,4,5-Trisphosphate; Isoquinolines; Male; Rats; Rats, Sprague-Dawley; Submandibular Gland; Sulfonamides; Thapsigargin | 1999 |
Adrenomedullin inhibits transmural pressure induced mesangial cell proliferation through activation of protein kinase A.
Topics: Adrenomedullin; Animals; Bucladesine; Calcitonin Gene-Related Peptide; Cell Division; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA; Enzyme Activation; Enzyme Inhibitors; Glomerular Mesangium; Humans; Isoquinolines; Membrane Proteins; Peptide Fragments; Peptides; Pressure; Rats; Receptors, Adrenomedullin; Receptors, Peptide; Sulfonamides | 1999 |
Follicle-stimulating hormone inhibits all-trans-retinoic acid-induced retinoic acid receptor alpha nuclear localization and transcriptional activation in mouse Sertoli cell lines.
Topics: Animals; Bucladesine; Cell Line; Cell Nucleus; Cyclic AMP-Dependent Protein Kinases; Fluorescent Antibody Technique; Follicle Stimulating Hormone; Gene Expression Regulation; Genes, Reporter; Isoquinolines; Male; Mice; Nuclear Proteins; Receptors, FSH; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Sertoli Cells; Signal Transduction; Sulfonamides; Transcriptional Activation; Transfection; Tretinoin | 2000 |
Stimulation of Ca(2+)-dependent exocytosis of the sperm acrosome by cAMP acting downstream of phospholipase A2.
Topics: Acrosome; Acrosome Reaction; Analysis of Variance; Animals; Aristolochic Acids; Bucladesine; Caffeine; Calcimycin; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Enzyme Inhibitors; Ionophores; Isoquinolines; Lysophosphatidylcholines; Male; Phenanthrenes; Phospholipases A; Phospholipases A2; Protein Kinase Inhibitors; Sheep; Stimulation, Chemical; Sulfonamides | 2000 |
Role of cAMP-dependent pathway in eosinophil apoptosis and survival.
Topics: Apoptosis; Biological Transport; Bucladesine; Cell Compartmentation; Cell Nucleus; Cell Survival; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Eosinophils; Humans; Hypersensitivity, Immediate; Interleukin-5; Isoquinolines; Janus Kinase 2; Mitogen-Activated Protein Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Signal Transduction; Sulfonamides | 2000 |
A common downstream signaling activity of osteoclast survival factors that prevent nitric oxide-promoted osteoclast apoptosis.
Topics: Animals; Apoptosis; Bucladesine; Calcitonin; Caspases; Cell Survival; Cells, Cultured; Coculture Techniques; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Interleukin-1; Isoquinolines; Male; Mice; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Osteoclasts; Rabbits; Signal Transduction; Sulfonamides | 2000 |
Prostaglandin E2-induced sensitization of bradykinin-evoked responses in rat dorsal root ganglion neurons is mediated by cAMP-dependent protein kinase A.
Topics: Adenylyl Cyclases; Animals; Bradykinin; Bucladesine; Calcium; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Drug Synergism; Enzyme Inhibitors; Ganglia, Spinal; Inositol 1,4,5-Trisphosphate; Isoquinolines; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Substance P; Sulfonamides; Tritium | 2000 |
Glut-1 translocation in FRTL-5 thyroid cells: role of phosphatidylinositol 3-kinase and N-glycosylation.
Topics: Androstadienes; Animals; Biological Transport; Bucladesine; Cell Line; Chromones; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Gene Expression; Glucose; Glucose Transporter Type 1; Glycosylation; Insulin; Isoquinolines; Monosaccharide Transport Proteins; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Rats; Sulfonamides; Thyroid Gland; Thyrotropin; Tunicamycin; Wortmannin | 2000 |
Protein kinase A-dependent stimulation of rat type II secreted phospholipase A(2) gene transcription involves C/EBP-beta and -delta in vascular smooth muscle cells.
Topics: Animals; Bucladesine; CCAAT-Enhancer-Binding Protein-beta; CCAAT-Enhancer-Binding Protein-delta; CCAAT-Enhancer-Binding Proteins; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Enzyme Induction; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Isoquinolines; Luciferases; Male; Muscle, Smooth, Vascular; Oligonucleotides; Phospholipases A; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Sulfonamides; Transcription Factors; Transcription, Genetic; Transfection | 2000 |
Modulation of thapsigargin-induced calcium mobilisation by cyclic AMP-elevating agents in human lymphocytes is insensitive to the action of the protein kinase A inhibitor H-89.
Topics: Adenosine Triphosphatases; Bucladesine; Calcium; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytosol; Enzyme Inhibitors; Fluorescent Dyes; Fura-2; Humans; Isoquinolines; Lymphocytes; Microscopy, Fluorescence; Milrinone; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Rolipram; Sulfonamides; Thapsigargin; Time Factors | 2001 |
EP1 and EP4 receptors mediate exocytosis evoked by prostaglandin E(2) in guinea-pig antral mucous cells.
Topics: Animals; Antineoplastic Agents; Bucladesine; Calcium; Cinnamates; Colforsin; Cyclic AMP; Dinoprostone; Enzyme Inhibitors; Exocytosis; Gastric Mucosa; Guinea Pigs; Isoquinolines; Male; Microscopy, Video; Pyloric Antrum; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Sulfonamides | 2001 |
Role of cyclic adenosine 3',5'-monophosphate and serum albumin in head-to-head agglutination of boar spermatozoa.
Topics: 1-Methyl-3-isobutylxanthine; Animals; beta-Cyclodextrins; Bucladesine; Cells, Cultured; Culture Media; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclodextrins; Enzyme Inhibitors; Glycoproteins; Isoquinolines; Male; Marine Toxins; Oxazoles; Phosphoprotein Phosphatases; Serum Albumin; Signal Transduction; Sperm Agglutination; Sperm Capacitation; Sperm Motility; Spermatozoa; Sulfonamides; Swine; Thionucleotides | 2000 |
The inhibition of phosphatidylinositol-3-kinase induces neurite retraction and activates GSK3.
Topics: Androstadienes; Bucladesine; Calcium-Calmodulin-Dependent Protein Kinases; Cell Differentiation; Cell Fractionation; Chromones; Culture Media, Serum-Free; Cyclic AMP; Enzyme Activation; Enzyme Inhibitors; Genes, Reporter; Glycogen Synthase Kinase 3; Humans; Immunoblotting; Isoquinolines; Lithium Chloride; Microtubule-Associated Proteins; Morpholines; Neurites; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Recombinant Proteins; Sulfonamides; Transfection; Tubulin; Tumor Cells, Cultured; Wortmannin | 2001 |
Cardioprotective effect afforded by transient exposure to phosphodiesterase III inhibitors: the role of protein kinase A and p38 mitogen-activated protein kinase.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Blood Flow Velocity; Bucladesine; Calcium-Calmodulin-Dependent Protein Kinases; Cardiovascular Agents; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 3; Dogs; Enzyme Inhibitors; Flavonoids; Hemodynamics; Imidazoles; Indoles; Isoquinolines; Maleimides; Milrinone; Mitogen-Activated Protein Kinases; Myocardial Infarction; p38 Mitogen-Activated Protein Kinases; Phosphodiesterase Inhibitors; Protein Kinase C; Pyridines; Pyridones; Sulfonamides; Ventricular Fibrillation | 2001 |
Age-dependent stimulation of Leydig cell steroidogenesis by interleukin-1 isoforms.
Topics: Aging; Animals; Bucladesine; Cell Division; Enzyme Inhibitors; Interleukin-1; Isoquinolines; Leydig Cells; Male; Naphthalenes; Nifedipine; Protein Isoforms; Rats; Rats, Sprague-Dawley; Receptors, Interleukin-1; Sulfonamides; Testosterone; Time Factors | 2001 |
Herpesvirus quiescence in neuronal cells IV: virus activation induced by pituitary adenylate cyclase-activating polypeptide (PACAP) involves the protein kinase A pathway.
Topics: Animals; Bucladesine; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Encephalitis, Herpes Simplex; Enzyme Inhibitors; Herpesvirus 1, Human; Indoles; Isoquinolines; Maleimides; Neurons; Neuropeptides; PC12 Cells; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Sulfonamides; Thionucleotides; Virus Latency | 2001 |
Controls of EGF-induced morphological transformation of human bronchial epithelial cells.
Topics: Bronchi; Bucladesine; Cell Line; Cells, Cultured; Dose-Response Relationship, Drug; Drug Antagonism; Enzyme Inhibitors; Epidermal Growth Factor; Epithelial Cells; ErbB Receptors; Humans; Isoquinolines; Kinetics; Phosphorylation; Pseudopodia; Respiratory Mucosa; Sulfonamides; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta | 2001 |
Glucose and cAMP regulate the L-type pyruvate kinase gene by phosphorylation/dephosphorylation of the carbohydrate response element binding protein.
Topics: Amino Acid Sequence; Animals; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Binding Sites; Bucladesine; Cantharidin; Carbohydrate Metabolism; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA; DNA-Binding Proteins; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Glucose; Helix-Loop-Helix Motifs; Isoquinolines; Leucine Zippers; Male; Mice; Molecular Sequence Data; Mutagenesis; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase Inhibitors; Pyruvate Kinase; Rats; Rats, Sprague-Dawley; Response Elements; Serine; Subcellular Fractions; Sulfonamides; Threonine; Transcription Factors; Transcription, Genetic | 2001 |
Histamine increases the expression of LOX-1 via H2 receptor in human monocytic THP-1 cells.
Topics: Bucladesine; Cell Differentiation; Colforsin; CREB-Binding Protein; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytokines; Dinoprostone; Enzyme Inhibitors; Gene Expression Regulation; Histamine; Humans; Isoquinolines; Macrophages; Monocytes; Nuclear Proteins; Promoter Regions, Genetic; Prostaglandin D2; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, LDL; Receptors, Oxidized LDL; RNA, Messenger; Scavenger Receptors, Class E; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Trans-Activators; Tumor Cells, Cultured; Up-Regulation | 2001 |
Regulation of plasminogen activator inhibitor-1 secretion by urokinase and tissue plasminogen activator in rat epithelioid-type smooth muscle cells.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bucladesine; Carbazoles; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Flavonoids; Genistein; Indoles; Isoquinolines; MAP Kinase Signaling System; Muscle, Smooth, Vascular; Phosphodiesterase Inhibitors; Phosphorylation; Plasminogen Activator Inhibitor 1; Protein Kinase C; Protein-Tyrosine Kinases; Pyrroles; Rats; Signal Transduction; src-Family Kinases; Stilbenes; Sulfonamides; Tissue Plasminogen Activator; Urokinase-Type Plasminogen Activator | 2002 |
Vector-averaged gravity regulates gene expression of receptor activator of NF-kappaB (RANK) ligand and osteoprotegerin in bone marrow stromal cells via cyclic AMP/protein kinase A pathway.
Topics: Animals; Bone Marrow Cells; Bucladesine; Carrier Proteins; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Enzyme Inhibitors; Gene Expression; Genes, Reporter; Glycoproteins; Gravitation; Isoquinolines; Luciferases; Membrane Glycoproteins; Osteoprotegerin; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Receptors, Cytoplasmic and Nuclear; Receptors, Tumor Necrosis Factor; RNA, Messenger; Stromal Cells; Sulfonamides | 2002 |
Different signal transduction pathways are involved during human sperm capacitation induced by biological and pharmacological agents.
Topics: 1-Methyl-3-isobutylxanthine; Alkaloids; Amino Acid Motifs; Benzophenanthridines; Bucladesine; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Female; Fetal Blood; Flavonoids; Follicular Fluid; Humans; Isoquinolines; Male; MAP Kinase Kinase Kinase 1; Phenanthridines; Phosphorylation; Progesterone; Protein Kinase C; Protein Serine-Threonine Kinases; Seminal Plasma Proteins; Signal Transduction; Sperm Capacitation; Sulfonamides; Tyrosine; Tyrphostins | 2002 |
Parathyroid hormone-related peptide regulation of chick tibial growth plate chondrocyte maturation requires protein kinase A.
Topics: Alkaline Phosphatase; Animals; Bucladesine; Calcium; Calcium Signaling; Cells, Cultured; Chelating Agents; Chickens; Chondrocytes; Collagen Type X; Cyclic AMP-Dependent Protein Kinases; DNA; Egtazic Acid; Enzyme Inhibitors; Growth Plate; Isoquinolines; Parathyroid Hormone-Related Protein; Peptide Hormones; Proteoglycans; RNA, Messenger; Sulfonamides; Tibia | 2002 |
Inhibition of human primary melanoma cell proliferation by histamine is enhanced by interleukin-6.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Bucladesine; Cell Division; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Gene Expression; Guanidines; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Imidazoles; Interleukin-6; Isoquinolines; Melanoma; Polymerase Chain Reaction; Receptors, Interleukin-6; Skin Neoplasms; Sulfonamides; Tumor Cells, Cultured | 2002 |
Regulation of glutamatergic neurotransmission in the striatum by presynaptic adenylyl cyclase-dependent processes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adrenergic beta-Antagonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bucladesine; Calcium; Calmodulin; Corpus Striatum; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Feedback; Female; Glutamic Acid; Imidazoles; Imines; Isoenzymes; Isoproterenol; Isoquinolines; Kainic Acid; Male; Mice; N-Methylaspartate; Nerve Tissue Proteins; Propranolol; Receptors, Adrenergic, beta; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Presynaptic; Second Messenger Systems; Sulfonamides; Synaptic Transmission; Trifluoperazine | 2003 |
Activation of protein kinase A induces neuronal differentiation of HiB5 hippocampal progenitor cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bucladesine; Cell Differentiation; Cell Line; Cell Size; Colforsin; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Green Fluorescent Proteins; Hippocampus; Isoquinolines; Luminescent Proteins; Neurons; Oligopeptides; Rats; Recombinant Fusion Proteins; Signal Transduction; Stem Cells; Sulfonamides | 2002 |
Phosphorylation of protein tyrosine residues in fresh and cryopreserved stallion spermatozoa under capacitating conditions.
Topics: Animals; beta-Cyclodextrins; Bucladesine; Caffeine; Cryopreservation; Cyclodextrins; Enzyme Inhibitors; Fluorescent Antibody Technique; Horses; Isoquinolines; Male; Phosphorylation; Sperm Capacitation; Spermatozoa; Sulfonamides; Tyrosine | 2003 |
Expression of adrenomedullin and its receptor by chondrocyte phenotype cells.
Topics: Adrenomedullin; Bucladesine; Cell Differentiation; Cell Division; Cells, Cultured; Chondrocytes; Colforsin; Culture Media, Conditioned; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Intracellular Signaling Peptides and Proteins; Isoquinolines; Membrane Proteins; Peptides; Phenotype; Radioimmunoassay; Receptor Activity-Modifying Proteins; Receptors, Adrenomedullin; Receptors, Peptide; Sulfonamides; Time Factors | 2003 |
Exploring the regulation of the expression of ChAT and VAChT genes in NG108-15 cells: implication of PKA and PI3K signaling pathways.
Topics: Animals; Bucladesine; Carrier Proteins; Choline O-Acetyltransferase; Chromones; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Gene Expression Regulation; Hybridomas; Isoquinolines; Membrane Transport Proteins; Mice; Morpholines; Phosphatidylinositol 3-Kinases; Rats; Receptors, Muscarinic; RNA, Messenger; Signal Transduction; Sulfonamides; Tumor Cells, Cultured; Vesicular Acetylcholine Transport Proteins; Vesicular Transport Proteins | 2003 |
Adjacent sequence controls the response polarity of nitric oxide-sensitive Sp factor binding sites.
Topics: Base Sequence; Binding Sites; Bucladesine; Cell Line; Cyclic AMP-Dependent Protein Kinases; DNA; DNA-Binding Proteins; Enzyme Activation; Enzyme Inhibitors; Humans; Isoquinolines; Mutagenesis, Site-Directed; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Promoter Regions, Genetic; Sp1 Transcription Factor; Sp3 Transcription Factor; Sulfonamides; Transcription Factor AP-1; Transcription Factors; Transfection; Tumor Necrosis Factor-alpha | 2003 |
Phosphorylation of the alpha4 subunit of human alpha4beta2 nicotinic receptors: role of cAMP-dependent protein kinase (PKA) and protein kinase C (PKC).
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Bucladesine; Carcinogens; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Humans; Indoles; Isoquinolines; Neurons; Phosphorylation; Protein Kinase C; Receptors, Nicotinic; Sulfonamides; Tetradecanoylphorbol Acetate; Thionucleotides; Transfection | 2003 |
Modulation of the reactive oxygen species (ROS) generation mediated by cyclic AMP-elevating agents or Interleukin 10 in granulocytes from type 2 diabetic patients (NIDDM): a PKA-independent phenomenon.
Topics: Aged; Aminophylline; Bucladesine; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Female; Granulocytes; Humans; Interleukin-10; Isoquinolines; Male; Middle Aged; Reactive Oxygen Species; Reference Values; Sulfonamides | 2003 |
cAMP inhibits natriuretic peptide receptor-B activity and increases C-type natriuretic peptide in FRTL-5 rat thyroid cells.
Topics: Animals; Bucladesine; Calcium; Carbazoles; Cell Line; Chelating Agents; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Depression, Chemical; Dose-Response Relationship, Drug; Guanylate Cyclase; Immunohistochemistry; Indoles; Isoquinolines; Natriuretic Peptide, C-Type; Pyrroles; Rats; Receptors, Atrial Natriuretic Factor; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Sulfonamides; Thyroid Gland; Thyrotropin; Time Factors | 2004 |
Protein kinase A and calcium/calmodulin-dependent protein kinase II regulate glycine and GABA release in auditory brain stem nuclei.
Topics: Animals; Benzylamines; Bucladesine; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cochlea; Cochlear Nucleus; Cyclic AMP-Dependent Protein Kinases; Denervation; Enzyme Inhibitors; gamma-Aminobutyric Acid; Glycine; Guinea Pigs; Isoquinolines; Neuronal Plasticity; Olivary Nucleus; Sulfonamides | 2004 |
Induction of hyaluronic acid synthase 2 (HAS2) in human vascular smooth muscle cells by vasodilatory prostaglandins.
Topics: 6-Ketoprostaglandin F1 alpha; Acetophenones; Alprostadil; Arteriosclerosis; Becaplermin; Benzopyrans; Bucladesine; Carotid Artery Diseases; Carotid Artery, Internal; Cells, Cultured; Colforsin; Cyclic AMP; Cyclooxygenase 2; Enzyme Induction; Epoprostenol; Extracellular Matrix; Glucuronosyltransferase; Humans; Hyaluronan Synthases; Hyaluronic Acid; Iloprost; Indoles; Isoenzymes; Isoquinolines; Macrophages; Maleimides; Membrane Proteins; Muscle Cells; Muscle, Smooth, Vascular; Pertussis Toxin; Platelet-Derived Growth Factor; Prostaglandin-Endoperoxide Synthases; Proto-Oncogene Proteins c-sis; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; RNA, Messenger; RNA, Small Interfering; Sulfonamides; Vasodilator Agents | 2004 |
cAMP-induced astrocytic differentiation of C6 glioma cells is mediated by autocrine interleukin-6.
Topics: Animals; Astrocytes; Blotting, Western; Brain Neoplasms; Bucladesine; Cell Differentiation; Cell Line, Tumor; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Genes, Reporter; Glial Fibrillary Acidic Protein; Glioma; Interleukin-6; Isoquinolines; Microscopy, Fluorescence; Models, Biological; Phosphorylation; Plasmids; Promoter Regions, Genetic; Rats; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; STAT3 Transcription Factor; Sulfonamides; Theophylline; Time Factors; Trans-Activators; Transcription, Genetic | 2004 |
Differential regulation of inducible nitric oxide synthase and cytokine gene expression by forskolin and dibutyryl-cAMP in lipopolysaccharide-stimulated murine BV2 microglial cells.
Topics: Animals; Blotting, Northern; Bucladesine; Cell Line; Colforsin; Cytokines; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Gene Expression Regulation; Isoquinolines; Lipopolysaccharides; Mice; Microglia; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Time Factors | 2004 |
Possible involvement of p38 MAP kinase in prostaglandin E1-induced ALP activity in osteoblast-like cells.
Topics: Adenylyl Cyclases; Alkaline Phosphatase; Alprostadil; Animals; Bucladesine; Cell Differentiation; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Imidazoles; Isoquinolines; Mice; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Sulfonamides | 2004 |
Up-regulation of IL-4 production by the activated cAMP/cAMP-dependent protein kinase (protein kinase A) pathway in CD3/CD28-stimulated naive T cells.
Topics: Animals; Bucladesine; Calcitonin Gene-Related Peptide; CD28 Antigens; CD3 Complex; Cell Differentiation; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; DNA-Binding Proteins; Down-Regulation; Humans; Interferon-gamma; Interleukin-2; Interleukin-4; Isoquinolines; Jurkat Cells; Male; Mice; Mice, Inbred BALB C; NFATC Transcription Factors; Nuclear Proteins; RNA, Messenger; Signal Transduction; Sulfonamides; Th1 Cells; Th2 Cells; Transcription Factors; Up-Regulation | 2004 |
Irsogladine, an anti-ulcer drug, suppresses superoxide production by inhibiting phosphodiesterase type 4 in human neutrophils.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adult; Anti-Ulcer Agents; Bucladesine; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 1; Cyclic Nucleotide Phosphodiesterases, Type 4; Dose-Response Relationship, Drug; Gastric Mucosa; Humans; Isoenzymes; Isoquinolines; Neutrophils; Rolipram; Sulfonamides; Superoxides; Triazines | 2004 |
Glucose stimulates the expression and activities of nitric oxide synthases in incubated rat islets: an effect counteracted by GLP-1 through the cyclic AMP/PKA pathway.
Topics: Animals; Bucladesine; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Cyclic N-Oxides; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Free Radical Scavengers; Glucagon; Glucagon-Like Peptide 1; Glucose; Imidazoles; Insulin; Insulin Secretion; Islets of Langerhans; Isoquinolines; Male; Microdissection; Microscopy, Confocal; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peptide Fragments; Protein Kinase Inhibitors; Protein Precursors; Rats; Rats, Sprague-Dawley; Sulfonamides | 2005 |
Regulation of thrombomodulin expression in human vascular smooth muscle cells by COX-2-derived prostaglandins.
Topics: Alprostadil; Blood Coagulation; Bucladesine; Carotid Artery Diseases; Carotid Artery, Internal; Cells, Cultured; Colforsin; Coronary Vessels; Culture Media, Serum-Free; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Epoprostenol; Etoricoxib; Gene Expression Profiling; Gene Expression Regulation; Humans; Iloprost; Isoquinolines; Mammary Arteries; Membrane Proteins; Models, Biological; Myocytes, Smooth Muscle; Oligonucleotide Array Sequence Analysis; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyridines; Receptors, Prostaglandin; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP3 Subtype; RNA, Messenger; Saphenous Vein; Second Messenger Systems; Sulfonamides; Sulfones; Tetradecanoylphorbol Acetate; Thrombomodulin; Thrombophilia; Vasodilator Agents | 2005 |
Characterization of cAMP-dependent proteolysis of GATA-6.
Topics: Animals; Base Sequence; Benzylamines; Binding Sites; Bucladesine; Carbazoles; Cell Nucleus; CHO Cells; Cricetinae; Cyclic AMP; DNA-Binding Proteins; Enzyme Inhibitors; Flavonoids; GATA6 Transcription Factor; Humans; Imidazoles; Indole Alkaloids; Isoquinolines; MAP Kinase Kinase Kinase 1; MAP Kinase Signaling System; Molecular Sequence Data; Mutation; Naphthalenes; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Plasmids; Prostaglandin D2; Proteasome Endopeptidase Complex; Protein Binding; Pyridines; src-Family Kinases; Sulfonamides; Transcription Factors | 2005 |
PACAP protects neuronal differentiated PC12 cells against the neurotoxicity induced by a mitochondrial complex I inhibitor, rotenone.
Topics: Animals; Bucladesine; Caspase 3; Caspases; Cell Differentiation; Cell Survival; Colforsin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Intracellular Membranes; Isoquinolines; MAP Kinase Signaling System; Membrane Potentials; Mitochondria; Nerve Growth Factors; Neurons; Neuropeptides; Neurosecretory Systems; Neurotransmitter Agents; p38 Mitogen-Activated Protein Kinases; Parkinson Disease; PC12 Cells; Pituitary Adenylate Cyclase-Activating Polypeptide; Protein Kinase Inhibitors; Rats; Rotenone; Signal Transduction; Sulfonamides | 2005 |
Adiponectin suppression of high-glucose-induced reactive oxygen species in vascular endothelial cells: evidence for involvement of a cAMP signaling pathway.
Topics: Adiponectin; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Blotting, Western; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Electrophoresis, Polyacrylamide Gel; Endothelial Cells; Enzyme Activation; Glucose; Humans; Hydrogen Peroxide; Isoquinolines; Lipoproteins, LDL; Multienzyme Complexes; Protein Serine-Threonine Kinases; Reactive Oxygen Species; Recombinant Proteins; Ribonucleosides; Signal Transduction; Sulfonamides | 2006 |
Regulation of the prepronociceptin gene and its effect on neuronal differentiation.
Topics: Animals; Base Sequence; Bucladesine; Cell Differentiation; Cell Line; Chromatin Immunoprecipitation; Cyclic AMP Response Element-Binding Protein; Fetus; Gene Expression Regulation, Developmental; Hippocampus; Humans; Hydroxamic Acids; Isoquinolines; Mice; Molecular Sequence Data; Neurons; Nociceptin; Opioid Peptides; Plicamycin; Promoter Regions, Genetic; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Sequence Alignment; Sulfonamides; Transcription, Genetic; Transfection | 2006 |
Activation dependent expression of MMPs in peripheral blood mononuclear cells involves protein kinase A.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Bucladesine; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Humans; Indomethacin; Isoquinolines; Lectins; Leukocytes, Mononuclear; Matrix Metalloproteinases; Prostaglandin-Endoperoxide Synthases; Protein Kinase Inhibitors; Sulfonamides | 2007 |
Tyrosine phosphorylation of a 38-kDa capacitation-associated buffalo (Bubalus bubalis) sperm protein is induced by L-arginine and regulated through a cAMP/PKA-independent pathway.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Bucladesine; Buffaloes; Cell Survival; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluorescent Antibody Technique; Heparin; Isoquinolines; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Osmolar Concentration; Phosphodiesterase Inhibitors; Phosphoproteins; Phosphorylation; Protein Kinase Inhibitors; Sperm Capacitation; Sperm Motility; Spermatozoa; Sulfonamides; Tyrosine | 2008 |
Regulation of Leydig cell steroidogenesis by extracellular signal-regulated kinase 1/2: role of protein kinase A and protein kinase C signaling.
Topics: Animals; Blotting, Western; Bucladesine; Butadienes; Cell Line, Tumor; Chorionic Gonadotropin; Cyclic AMP-Dependent Protein Kinases; DAX-1 Orphan Nuclear Receptor; DNA-Binding Proteins; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Isoquinolines; Leydig Cells; Male; Mice; Nitriles; Phosphoproteins; Phosphorylation; Progesterone; Protein Kinase C; Receptors, Retinoic Acid; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; Scavenger Receptors, Class B; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate | 2007 |
Role of calcium messenger systems in ACTH-induced cortisol production in bovine adrenal fasciculo-reticularis cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adrenocorticotropic Hormone; Animals; Bucladesine; Calcium; Calcium Signaling; Cattle; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Hydrocortisone; Isoquinolines; Naphthalenes; Phospholipase A2 Inhibitors; Phospholipases A2; Primaquine; Protein Kinase C; Protein Kinase Inhibitors; Quinacrine; Second Messenger Systems; Sulfonamides; Zona Fasciculata | 2007 |
Regulation of relaxin 3 gene expression via cAMP-PKA in a neuroblastoma cell line.
Topics: Animals; Base Sequence; Brain Stem; Bucladesine; Carbazoles; Cell Line, Tumor; Colforsin; Conserved Sequence; Corticotropin-Releasing Hormone; Gene Expression; Intracellular Signaling Peptides and Proteins; Isoquinolines; Male; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Promoter Regions, Genetic; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Relaxin; Sulfonamides | 2009 |
Resveratrol, a naturally occurring diphenolic compound, affects lipogenesis, lipolysis and the antilipolytic action of insulin in isolated rat adipocytes.
Topics: Adipocytes; Animals; Bucladesine; Carbon Dioxide; Cell Separation; Cell Survival; Cyclic AMP; Epinephrine; Fatty Acids; Glycerol; Insulin; Isoquinolines; Lactic Acid; Lipogenesis; Lipolysis; Male; Phenols; Rats; Rats, Wistar; Resveratrol; Stilbenes; Sulfonamides | 2009 |
Expression and in vitro regulation of pituitary adenylate cyclase-activating polypeptide (pacap38) and its type I receptor (pac1-r) in the gonads of tilapia (Oreochromis mossambicus).
Topics: Amino Acid Sequence; Animals; Base Sequence; Bucladesine; Colforsin; Female; Fishes; Gene Expression; Gonads; Immunohistochemistry; Isoquinolines; Male; Molecular Sequence Data; Pituitary Adenylate Cyclase-Activating Polypeptide; Protein Kinase Inhibitors; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Alignment; Sulfonamides; Tilapia; Tissue Culture Techniques; Up-Regulation | 2009 |
Phosphorylation of myristoylated alanine-rich C kinase substrate is involved in the cAMP-dependent amylase release in parotid acinar cells.
Topics: Acetophenones; Amylases; Animals; Benzopyrans; Bucladesine; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytosol; Enzyme Inhibitors; Intracellular Signaling Peptides and Proteins; Isoproterenol; Isoquinolines; Male; Membrane Proteins; Myristoylated Alanine-Rich C Kinase Substrate; Naphthalenes; Parotid Gland; Peptide Fragments; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Protein Transport; Rats; Rats, Sprague-Dawley; Sulfonamides | 2009 |
Enhanced antiproliferative and proapoptotic effects on prostate cancer cells by simultaneously inhibiting androgen receptor and cAMP-dependent protein kinase A.
Topics: Adenocarcinoma; Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Anilides; Animals; Apoptosis; Bucladesine; Cell Division; Colforsin; Cyclic AMP-Dependent Protein Kinase RIalpha Subunit; Enzyme Induction; Gene Knockdown Techniques; Humans; Isoquinolines; Male; Metribolone; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Nitriles; Prostatic Neoplasms; Receptors, Androgen; RNA, Small Interfering; Signal Transduction; Sulfonamides; Tosyl Compounds | 2010 |
Prostaglandin E2 inhibits advanced glycation end product-induced adhesion molecule expression, cytokine production, and lymphocyte proliferation in human peripheral blood mononuclear cells.
Topics: Adenylyl Cyclases; Bucladesine; Cell Adhesion Molecules; Cell Proliferation; Cell Separation; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytokines; Dinoprostone; Enzyme Activation; Flow Cytometry; Glycation End Products, Advanced; Humans; In Vitro Techniques; Isoquinolines; Lymphocytes; Monocytes; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Sulfonamides | 2009 |
The ceramide-1-phosphate analogue PCERA-1 modulates tumour necrosis factor-alpha and interleukin-10 production in macrophages via the cAMP-PKA-CREB pathway in a GTP-dependent manner.
Topics: Adenylyl Cyclases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bucladesine; Calcium Signaling; Cell Line; Cell Membrane; Ceramides; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Enzyme Inhibitors; Genes, Reporter; Guanosine Triphosphate; Imidazoles; Indoles; Interleukin-10; Isoquinolines; Lipopolysaccharides; Macrophages; Mice; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Pyridines; Response Elements; Ribosomal Protein S6 Kinases, 90-kDa; Rolipram; Signal Transduction; Sulfonamides; Transfection; Tumor Necrosis Factor-alpha | 2010 |
Acute stimulation of white adipocyte respiration by PKA-induced lipolysis.
Topics: Adipocytes, White; Aerobiosis; Anaerobiosis; Animals; Bucladesine; Colforsin; Cyclic AMP; Humans; Ion Channels; Isoproterenol; Isoquinolines; Male; Mice; Mice, Knockout; Mitochondrial Proteins; Oxygen Consumption; Protein Kinase Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Sulfonamides; Uncoupling Protein 2 | 2010 |
Inhibition of the mammalian target of rapamycin promotes cyclic AMP-induced differentiation of NG108-15 cells.
Topics: Adenosine Triphosphate; Animals; Autophagy; Bucladesine; Cell Count; Cell Cycle; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Drug Synergism; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gene Knockdown Techniques; Humans; Isoquinolines; Mice; Microtubule-Associated Proteins; Phosphorylation; Sirolimus; Sulfonamides; TOR Serine-Threonine Kinases | 2010 |
cAMP-dependent protein kinase A activity modulates topiramate potentiation of GABA(A) receptors.
Topics: Animals; Anticonvulsants; Biophysics; Bucladesine; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Fructose; gamma-Aminobutyric Acid; Humans; Isoquinolines; Larva; Membrane Potentials; Microinjections; Oocytes; Patch-Clamp Techniques; Protein Kinase Inhibitors; Protein Subunits; Receptors, GABA-A; Sulfonamides; Topiramate; Xenopus | 2011 |
Effects of pentoxifylline and H-89 on epileptogenic activity of bucladesine in pentylenetetrazol-treated mice.
Topics: Animals; Bucladesine; Dose-Response Relationship, Drug; Drug Interactions; Isoquinolines; Male; Mice; Pentoxifylline; Pentylenetetrazole; Phosphodiesterase Inhibitors; Protein Kinase Inhibitors; Seizures; Sulfonamides | 2011 |
Regulation of asymmetrical cytokinesis by cAMP during meiosis I in mouse oocytes.
Topics: 1-Methyl-3-isobutylxanthine; Anaphase; Animals; Asymmetric Cell Division; Bucladesine; Cell Movement; Cells, Cultured; Chromosomes, Mammalian; Cyclic AMP; Cytokinesis; Female; Intracellular Space; Isoquinolines; Meiosis; Mice; Mice, Inbred ICR; Microinjections; Myosin Type II; Oocytes; Sulfonamides | 2012 |
β-Adrenergic stimulation increases Cav3.1 activity in cardiac myocytes through protein kinase A.
Topics: Adrenergic beta-Agonists; Animals; Bucladesine; Calcium; Calcium Channels, T-Type; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Gene Expression Regulation; Gene Knockout Techniques; Heart Ventricles; Isoproterenol; Isoquinolines; Mice; Mice, Transgenic; Myocytes, Cardiac; Protein Kinase Inhibitors; Real-Time Polymerase Chain Reaction; Receptors, Adrenergic, beta; Signal Transduction; Sinoatrial Node; Sulfonamides | 2012 |
Dynamic alterations in the expression and localization of ACTL7a during capacitation in mouse spermatozoa.
Topics: Actins; Animals; Bicarbonates; Bucladesine; Calcium; Cyclic AMP-Dependent Protein Kinases; Isoquinolines; Male; Mice; Mice, Inbred ICR; Protein Kinase C; Protein Kinase Inhibitors; Signal Transduction; Sperm Capacitation; Spermatozoa; Sulfonamides | 2013 |
A cAMP analog reverses contextual and tone memory deficits induced by a PKA inhibitor in Pavlovian fear conditioning.
Topics: Animals; Bucladesine; Conditioning, Classical; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Fear; Isoquinolines; Male; Memory; Rats; Rats, Wistar; Sulfonamides | 2013 |
Cyclic-AMP mediated regulation of ABCB mRNA expression in mussel haemocytes.
Topics: 5' Untranslated Regions; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bucladesine; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Fluoxetine; Gene Expression Regulation; Hemocytes; Humans; Isoquinolines; Models, Biological; Mytilus; Norepinephrine; Promoter Regions, Genetic; Propranolol; Receptors, Serotonin, 5-HT1; RNA, Messenger; Sequence Analysis, DNA; Serotonin; Serotonin Receptor Agonists; Signal Transduction; Sulfonamides; Up-Regulation | 2013 |
Dual effect of cAMP agonist on ameliorative function of PKA inhibitor in morphine-dependent mice.
Topics: Animals; Bucladesine; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Drug Therapy, Combination; Isoquinolines; Male; Mice; Morphine Dependence; Naloxone; Narcotic Antagonists; Substance Withdrawal Syndrome; Sulfonamides | 2014 |
Prostaglandin I2-IP signalling regulates human Th17 and Treg cell differentiation.
Topics: Bucladesine; Cell Differentiation; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Epoprostenol; Forkhead Transcription Factors; Gene Expression Regulation; Humans; Iloprost; Interleukin-17; Interleukin-2; Interleukin-6; Isoquinolines; Nuclear Receptor Subfamily 1, Group F, Member 3; Phosphorylation; Platelet Aggregation Inhibitors; Receptors, Epoprostenol; RNA, Messenger; Signal Transduction; STAT3 Transcription Factor; STAT5 Transcription Factor; Sulfonamides; T-Lymphocytes, Regulatory; Th17 Cells | 2013 |
Involvement of the Notch pathway in terminal astrocytic differentiation: role of PKA.
Topics: Adjuvants, Immunologic; Animals; Astrocytes; Astrocytoma; Bucladesine; Cell Differentiation; Cell Line, Tumor; Colforsin; Glial Fibrillary Acidic Protein; Intracellular Membranes; Isoquinolines; Protein Kinase Inhibitors; Protein Transport; Rats; Receptors, Notch; Signal Transduction; Subcellular Fractions; Sulfonamides; Transcriptional Activation; Transfection; Up-Regulation | 2013 |
PKA Phosphorylates the ATPase Inhibitory Factor 1 and Inactivates Its Capacity to Bind and Inhibit the Mitochondrial H(+)-ATP Synthase.
Topics: Adenosine Triphosphate; Animals; ATPase Inhibitory Protein; Binding Sites; Bucladesine; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Assays; Gene Expression Regulation; Glycolysis; HCT116 Cells; Humans; Isoquinolines; Kinetics; Mice; Mitochondria, Heart; Mitochondrial Proton-Translocating ATPases; Models, Molecular; Myocardium; Oxidative Phosphorylation; Phosphorylation; Protein Binding; Proteins; Signal Transduction; Sulfonamides | 2015 |
Actin Polymerization: An Event Regulated by Tyrosine Phosphorylation During Buffalo Sperm Capacitation.
Topics: Acrosome Reaction; Actins; Animals; Bucladesine; Buffaloes; Hydrogen Peroxide; Isoquinolines; Male; Phosphorylation; Polymerization; Sperm Capacitation; Spermatozoa; Sulfonamides; Teprotide; Tyrosine | 2015 |
cAMP/PKA signaling pathway contributes to neuronal apoptosis via regulating IDE expression in a mixed model of type 2 diabetes and Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Apoptosis; Blood Glucose; Bucladesine; Cells, Cultured; Cyclic AMP; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucose Tolerance Test; Humans; Insulysin; Isoquinolines; Mice; Neurons; Protein Kinases; Signal Transduction; Sulfonamides | 2018 |
Mechanisms by which in vitro meiotic arrest and sexual maturity improve developmental potential of mouse oocytes.
Topics: Alpha-Amanitin; Animals; Bucladesine; Cell Cycle Checkpoints; Cell Nucleolus; Chromatin; Cumulus Cells; Cyclin-Dependent Kinase 5; Cytoplasm; Embryonic Development; Female; Isoquinolines; Meiosis; Mice; Oocytes; RNA; RNA Polymerase II; Roscovitine; Sexual Maturation; Sulfonamides; Transcription, Genetic | 2017 |
Interactive involvement of hippocampal cAMP/PKA and cyclooxygenase-2 signaling pathways in spatial learning in the Morris water maze.
Topics: Animals; Bucladesine; Celecoxib; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Hippocampus; Isoquinolines; Male; Maze Learning; Protein Kinase Inhibitors; Rats; Rats, Wistar; Signal Transduction; Sulfonamides | 2018 |
Dibutyryl cAMP- or Interleukin-6-induced astrocytic differentiation enhances mannose binding lectin (MBL)-associated serine protease (MASP)-1/3 expression in C6 glioma cells.
Topics: Animals; Astrocytes; Brain Neoplasms; Bucladesine; Cell Differentiation; Cell Line, Tumor; Glioma; Immunity, Innate; Interleukin-6; Isoquinolines; Mannose-Binding Protein-Associated Serine Proteases; Phosphorylation; Protein Kinase Inhibitors; Rats; Recombinant Proteins; RNA, Messenger; STAT3 Transcription Factor; Sulfonamides | 2018 |
Cyclic AMP Regulates Key Features of Macrophages via PKA: Recruitment, Reprogramming and Efferocytosis.
Topics: Animals; Annexin A1; Apoptosis; Arginase; Bucladesine; CD36 Antigens; Cell Polarity; Cellular Reprogramming; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Inflammation; Interleukin-4; Isoquinolines; Lipopolysaccharides; Macrophages; Male; Mice, Inbred BALB C; Models, Biological; Monocytes; Neutrophils; Phagocytosis; Phenotype; Phosphorylation; Pleural Cavity; Receptors, CCR2; STAT3 Transcription Factor; Sulfonamides; Time Factors | 2020 |