Page last updated: 2024-08-23

bucindolol and metoprolol

bucindolol has been researched along with metoprolol in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (23.08)18.2507
2000's17 (65.38)29.6817
2010's3 (11.54)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chandrasena, G; Gavai, AV; Nayeem, A; Santone, K; Vaz, RJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Bristow, MR; Handwerger, D; Klein, J; Larrabee, P; Minobe, W; Müller-Beckmann, B; Port, JD; Roden, R; Skerl, L1
Eichhorn, EJ; Hatfield, B; Heesch, CM; Marcoux, L1
Abraham, WT; Bristow, MR; Crisman, TS; Gilbert, EM; Hattler, BG; Larrabee, P; Lowes, BD; Robertson, AD; White, M; Yoshikawa, T1
Carson, PE1
Eichhorn, EJ; Fesmire, SI; Kennedy, HL; Lyyski, DS; Marcoux, LG; Sprague, MK1
Witkowska, M1
Bristow, MR1
Böhm, M; Cremers, B; Flesch, M; Höper, A; Maack, C; Südkamp, M1
Hjalmarson, A1
Krum, H; Whorlow, SL1
Chavey, WE1
Coutinho, J1
Bölck, B; Brixius, K; Bundkirchen, A; Mehlhorn, U; Schwinger, RH1
Czuriga, I; Edes, I1
Bölck, B; Brixius, K; Bundkirchen, A; Schwinger, RH1
Cherubini, A; Di Lenarda, A; Perkan, A; Salvatore, L; Sinagra, G1
Böhm, M; Dabew, E; Engelhardt, S; Lohse, MJ; Lorenz, K; Maack, C; Schäfers, HJ; Vlaskin, L1
Deedwania, P; Fagerberg, B; Ghali, J; Goldstein, S; Gottlieb, S; Hjalmarson, A; Kjekshus, J; Waagstein, F; Wedel, H; Wikstrand, J1
Coffey, CS; Curtis, JP; Foody, JM; Hebert, PR; Ko, DT; Krumholz, HM; Sedrakyan, A1
Anh, D; Marine, JE1
Adams, KF1
Remme, WJ1
Abraham, WT; Al-Khalidi, HR; Aleong, RG; Anand, IS; Bristow, MR; Clark, RL; Connolly, SJ; Davis, GW; Dignacco, P; Dufton, C; Emery, LL; Healey, JS; Marshall, DA; Piccini, JP; Sauer, WH; Steinberg, BA; van Veldhuisen, DJ; White, M; Wilton, SB1
Abraham, WT; Aleong, R; Anand, IS; Ayala-Paredes, F; Bristow, MR; Carroll, IA; Connolly, SJ; Davis, G; Dufton, C; Emery, LL; Healey, JS; Ilkhanoff, L; Kao, DP; Khaykin, Y; Krueger, SK; Marshall, D; Merkely, B; Miloradović, V; Piccini, JP; Rienstra, M; Sauer, WH; van Veldhuisen, DJ; White, M; Wilton, SB; Wranicz, JK; Ziegler, PD1

Reviews

9 review(s) available for bucindolol and metoprolol

ArticleYear
Beta-blocker therapy in heart failure: pathophysiology and clinical results.
    Current problems in cardiology, 1999, Volume: 24, Issue:7

    Topics: Adrenergic beta-Antagonists; Aged; Bisoprolol; Carbazoles; Carvedilol; Clinical Trials as Topic; Exercise; Heart Failure; Heart Rate; Hemodynamics; Humans; Imidazoles; Male; Metoprolol; Middle Aged; Propanolamines; Propranolol; Quality of Life; Stroke Volume; Time Factors; Vasodilator Agents; Xamoterol

1999
beta-adrenergic receptor blockade in chronic heart failure.
    Circulation, 2000, Feb-08, Volume: 101, Issue:5

    Topics: Adrenergic beta-Antagonists; Bisoprolol; Carbazoles; Carvedilol; Chronic Disease; Heart Failure; Heart Function Tests; Humans; Metoprolol; Propanolamines; Receptors, Adrenergic, beta; Signal Transduction

2000
Meta-analysis of effect of beta-blocker therapy on mortality in patients with New York Heart Association class IV chronic congestive heart failure.
    The American journal of cardiology, 2000, Oct-15, Volume: 86, Issue:8

    Topics: Adrenergic beta-Antagonists; Benzopyrans; Bisoprolol; Carbazoles; Carvedilol; Ethanolamines; Heart Failure; Humans; Metoprolol; Nebivolol; Propanolamines

2000
The importance of beta blockers in the treatment of heart failure.
    American family physician, 2000, Dec-01, Volume: 62, Issue:11

    Topics: Adrenergic beta-Antagonists; Bisoprolol; Carbazoles; Carvedilol; Contraindications; Drug Administration Schedule; Female; Heart Failure; Humans; Male; Metoprolol; Patient Selection; Propanolamines; Randomized Controlled Trials as Topic; Severity of Illness Index

2000
[Adrenergic beta inhibitors in heart insufficiency: which and when?].
    Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology, 2001, Volume: 20 Suppl 3

    Topics: Adrenergic beta-Antagonists; Bisoprolol; Carbazoles; Carvedilol; Heart Failure; Humans; Metoprolol; Patient Selection; Propanolamines; Randomized Controlled Trials as Topic; Sympathetic Nervous System; Ventricular Dysfunction, Left

2001
[Role of beta-blockers in the treatment of chronic heart heart failure].
    Orvosi hetilap, 2001, Sep-16, Volume: 142, Issue:37

    Topics: Adrenergic beta-Antagonists; Bisoprolol; Carbazoles; Carvedilol; Chronic Disease; Controlled Clinical Trials as Topic; Disease Progression; Drug Administration Schedule; Heart Failure; Humans; Metoprolol; Myocardial Contraction; Patient Selection; Propanolamines; Survival Rate; Ventricular Dysfunction, Left; Ventricular Function, Left

2001
[Treatment of heart failure: an update].
    Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology, 2002, Volume: 3, Issue:7

    Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antidiuretic Hormone Receptor Antagonists; Antihypertensive Agents; Benzazepines; Bosentan; Carbazoles; Carvedilol; Death, Sudden, Cardiac; Defibrillators, Implantable; Double-Blind Method; Heart Failure; Heart-Assist Devices; Humans; Metoprolol; Multicenter Studies as Topic; Placebos; Propanolamines; Prospective Studies; Pyridines; Quality of Life; Randomized Controlled Trials as Topic; Sulfonamides; Tetrazoles; Valine; Valsartan; Vasodilator Agents

2002
Beta blockers as anti-arrhythmic agents.
    Heart failure reviews, 2004, Volume: 9, Issue:2

    Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Carbazoles; Carvedilol; Heart Failure; Humans; Metoprolol; Propanolamines; Randomized Controlled Trials as Topic; United States

2004
Beta-blockers in heart failure: how far have we progressed?
    Postgraduate medicine, 2002, Volume: 112, Issue:5 Suppl Un

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Bisoprolol; Carbazoles; Carvedilol; Contraindications; Heart Failure; Humans; Metoprolol; Propanolamines; Sympathetic Nervous System; Ventricular Dysfunction, Left

2002

Trials

5 trial(s) available for bucindolol and metoprolol

ArticleYear
Hemodynamic and energetic comparison of bucindolol and metoprolol for the treatment of congestive heart failure.
    The American journal of cardiology, 1995, Feb-15, Volume: 75, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Double-Blind Method; Heart Failure; Hemodynamics; Humans; Male; Metoprolol; Propanolamines; Retrospective Studies; Ventricular Function, Left

1995
Second- and third-generation beta-blocking drugs in chronic heart failure.
    Cardiovascular drugs and therapy, 1997, Volume: 11 Suppl 1

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Carbazoles; Cardiac Output, Low; Cardiomyopathy, Dilated; Carvedilol; Chronic Disease; Exercise Test; Heart Ventricles; Hemodynamics; Humans; Metoprolol; Middle Aged; Myocardial Ischemia; Oxygen Consumption; Propanolamines; Ventricular Function, Left

1997
Adverse effects of beta-blocker therapy for patients with heart failure: a quantitative overview of randomized trials.
    Archives of internal medicine, 2004, Jul-12, Volume: 164, Issue:13

    Topics: Adrenergic beta-Antagonists; Aged; Bisoprolol; Bradycardia; Carbazoles; Carvedilol; Dizziness; Fatigue; Female; Follow-Up Studies; Heart Conduction System; Heart Failure; Humans; Hypotension; Male; Metoprolol; Middle Aged; Propanolamines; Risk Factors; Risk Reduction Behavior; Severity of Illness Index; Statistics as Topic; Treatment Failure; Ventricular Dysfunction, Left; Withholding Treatment

2004
A genotype-directed comparative effectiveness trial of Bucindolol and metoprolol succinate for prevention of symptomatic atrial fibrillation/atrial flutter in patients with heart failure: Rationale and design of the GENETIC-AF trial.
    American heart journal, 2018, Volume: 199

    Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; DNA; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Genetic Testing; Genotype; Heart Failure; Humans; Male; Metoprolol; Middle Aged; Propanolamines; Prospective Studies; Receptors, Adrenergic, beta-1; Stroke Volume; Treatment Outcome

2018
Bucindolol for the Maintenance of Sinus Rhythm in a Genotype-Defined HF Population: The GENETIC-AF Trial.
    JACC. Heart failure, 2019, Volume: 7, Issue:7

    Topics: Adrenergic beta-Antagonists; Aged; Atrial Fibrillation; Electrocardiography; Female; Genotype; Heart Failure; Humans; Male; Metoprolol; Middle Aged; Mortality; Pharmacogenetics; Pharmacogenomic Variants; Precision Medicine; Propanolamines; Proportional Hazards Models; Receptors, Adrenergic, beta-1; Stroke Volume

2019

Other Studies

12 other study(ies) available for bucindolol and metoprolol

ArticleYear
A 3D-QSAR model for CYP2D6 inhibition in the aryloxypropanolamine series.
    Bioorganic & medicinal chemistry letters, 2005, Sep-01, Volume: 15, Issue:17

    Topics: Animals; Cytochrome P-450 CYP2D6 Inhibitors; Humans; Inhibitory Concentration 50; Models, Molecular; Propanolamines; Quantitative Structure-Activity Relationship; Substrate Specificity

2005
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Receptor pharmacology of carvedilol in the human heart.
    Journal of cardiovascular pharmacology, 1992, Volume: 19 Suppl 1

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Binding, Competitive; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Cyclic AMP; Guanylyl Imidodiphosphate; Humans; Iodocyanopindolol; Metoprolol; Myocardium; Pindolol; Propanolamines; Propranolol; Receptors, Adrenergic, beta; Vasodilator Agents

1992
Effect of selective versus nonselective beta blockade on QT dispersion in patients with nonischemic dilated cardiomyopathy.
    The American journal of cardiology, 1999, Aug-01, Volume: 84, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Death, Sudden, Cardiac; Electrocardiography; Female; Heart Conduction System; Humans; Male; Metoprolol; Middle Aged; Propanolamines; Retrospective Studies; Stroke Volume; Treatment Outcome

1999
[The role of beta-adrenergic blocking agents in treatment of heart failure].
    Polskie Archiwum Medycyny Wewnetrznej, 1999, Volume: 101, Issue:1

    Topics: Adrenergic beta-Antagonists; Bisoprolol; Carbazoles; Carvedilol; Heart Failure; Humans; Metoprolol; Propanolamines

1999
Different intrinsic activities of bucindolol, carvedilol and metoprolol in human failing myocardium.
    British journal of pharmacology, 2000, Volume: 130, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Carbazoles; Carvedilol; Catecholamines; Female; Guanylyl Imidodiphosphate; Heart Failure; Humans; In Vitro Techniques; Iodocyanopindolol; Male; Metoprolol; Middle Aged; Myocardial Contraction; Propanolamines

2000
[Beta blockers: the end of controversy].
    Archives des maladies du coeur et des vaisseaux, 2000, Volume: Spec No

    Topics: Adrenergic beta-Antagonists; Carbazoles; Cardiac Output, Low; Carvedilol; Cause of Death; Clinical Trials as Topic; Female; Humans; Male; Metoprolol; Middle Aged; Propanolamines; Survival Rate

2000
Nebivolol, bucindolol, metoprolol and carvedilol are devoid of intrinsic sympathomimetic activity in human myocardium.
    British journal of pharmacology, 2001, Volume: 133, Issue:8

    Topics: Adrenergic beta-Antagonists; Benzopyrans; Binding, Competitive; Bisoprolol; Carbazoles; Carvedilol; Ethanolamines; Female; Guanylyl Imidodiphosphate; Heart Ventricles; Humans; Imidazoles; In Vitro Techniques; Inhibitory Concentration 50; Isoproterenol; Male; Metoprolol; Middle Aged; Myocardial Contraction; Myocardium; Nebivolol; Propanolamines; Substrate Specificity; Sympathetic Nervous System; Sympathomimetics; Thermodynamics

2001
Bucindolol exerts agonistic activity on the propranolol-insensitive state of beta1-adrenoceptors in human myocardium.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 300, Issue:3

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aged; Atrial Function, Right; Benzopyrans; Ethanolamines; Female; Heart; Humans; In Vitro Techniques; Male; Metoprolol; Middle Aged; Myocardial Contraction; Myocardium; Nebivolol; Papillary Muscles; Propanolamines; Propranolol; Receptors, Adrenergic, beta-1; Ventricular Function, Left

2002
Partial agonist activity of bucindolol is dependent on the activation state of the human beta1-adrenergic receptor.
    Circulation, 2003, Jul-22, Volume: 108, Issue:3

    Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Atrial Function; Heart Atria; Heart Failure; Heart Rate; Humans; In Vitro Techniques; Male; Metoprolol; Mice; Mice, Transgenic; Middle Aged; Myocardial Contraction; Organ Specificity; Propanolamines; Propranolol; Receptors, Adrenergic, beta-1; Species Specificity; Xamoterol

2003
How should subgroup analyses affect clinical practice? Insights from the Metoprolol Succinate Controlled-Release/Extended-Release Randomized Intervention Trial in Heart Failure (MERIT-HF).
    Cardiac electrophysiology review, 2003, Volume: 7, Issue:3

    Topics: Adrenergic beta-Antagonists; Black People; Diabetic Angiopathies; Heart Failure; Humans; Hypertension; Meta-Analysis as Topic; Metoprolol; Multicenter Studies as Topic; Myocardial Infarction; Practice Patterns, Physicians'; Propanolamines; Randomized Controlled Trials as Topic

2003
Which beta-blocker is most effective in heart failure?
    Cardiovascular drugs and therapy, 2010, Volume: 24, Issue:4

    Topics: Adrenergic beta-Antagonists; Animals; Benzopyrans; Bisoprolol; Carbazoles; Carvedilol; Clinical Trials as Topic; Comorbidity; Diabetes Mellitus; Disease Progression; Ethanolamines; Heart Failure; Humans; Lung Diseases, Obstructive; Metoprolol; Myocardial Infarction; Nebivolol; Propanolamines; Treatment Outcome; Ventricular Dysfunction, Left; Ventricular Remodeling

2010