Compounds > btm 1042
Page last updated: 2024-09-03

btm 1042 and pirenzepine

btm 1042 has been researched along with pirenzepine in 3 studies

Compound Research Comparison

Studies
(btm 1042)		Trials
(btm 1042)		Recent Studies (post-2010)
(btm 1042)		Studies
(pirenzepine)		Trials
(pirenzepine)		Recent Studies (post-2010) (pirenzepine)
11003,812587140

Protein Interaction Comparison

ProteinTaxonomybtm 1042 (IC50)pirenzepine (IC50)
Muscarinic acetylcholine receptor M2Homo sapiens (human)0.6891
Muscarinic acetylcholine receptor M4Homo sapiens (human)0.5856
Muscarinic acetylcholine receptor M1Rattus norvegicus (Norway rat)0.6134
Muscarinic acetylcholine receptor M3Rattus norvegicus (Norway rat)0.6222
Muscarinic acetylcholine receptor M4Rattus norvegicus (Norway rat)0.6227
Muscarinic acetylcholine receptor M5Rattus norvegicus (Norway rat)0.6227
Muscarinic acetylcholine receptor M5Homo sapiens (human)0.3406
Muscarinic acetylcholine receptor M2Rattus norvegicus (Norway rat)0.6281
Muscarinic acetylcholine receptor M1Homo sapiens (human)0.0291
Muscarinic acetylcholine receptor M1Mus musculus (house mouse)0.75
Muscarinic acetylcholine receptor M3Homo sapiens (human)0.9556
Muscarinic acetylcholine receptor M4Mus musculus (house mouse)0.75
Muscarinic acetylcholine receptor M5Mus musculus (house mouse)0.75
Muscarinic acetylcholine receptor M3Mus musculus (house mouse)0.75
Muscarinic acetylcholine receptor M2Mus musculus (house mouse)0.51

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's2 (66.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baron, E; Boer, R; Eltze, M; Kromer, W1
Jackson, KN; Kachur, JF; Lowe, VC; Noronha-Blob, L; Sturm, BL1
Akaike, M; Konno, F; Nibori, Y; Takayanagi, I; Yamura, S1

Other Studies

3 other study(ies) available for btm 1042 and pirenzepine

ArticleYear
Telenzepine inhibits electrically-stimulated, acetylcholine plus histamine-mediated acid secretion in the mouse isolated stomach by blockade of M1 muscarine receptors.
    Naunyn-Schmiedeberg's archives of pharmacology, 1991, Volume: 343, Issue:1

    Topics: Acetylcholine; Alkaloids; Animals; Anti-Ulcer Agents; Electric Stimulation; Furans; Gastric Acid; Gastric Mucosa; Histamine; Mice; Muscarinic Antagonists; Naphthalenes; p-Methoxy-N-methylphenethylamine; Parasympatholytics; Piperidines; Pirenzepine; Stomach; Thiazepines; Vagus Nerve

1991
In vitro and in vivo antimuscarinic effects of (-)cis 2,3-dihydro-3-(4-methylpiperazinylmethyl)-2-phenyl-1,5 benzothiazepin-4-(5H)one HCl (BTM-1086) in guinea pig peripheral tissues.
    Life sciences, 1990, Volume: 46, Issue:17

    Topics: Animals; Atropine; Calcium; Female; Guinea Pigs; Heart Atria; Ileum; In Vitro Techniques; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Neurons; Parasympatholytics; Piperidines; Pirenzepine; Structure-Activity Relationship; Thiazepines; Tumor Cells, Cultured; Urinary Bladder; Vas Deferens

1990
cis(-)-2,3-Dihydro-3-(4-methylpiperazinylmethyl)-2-phenyl-1,5- benzothiazepin-4(5H)-one monohydrochloride and its butylbromide as M1-receptor antagonists.
    General pharmacology, 1987, Volume: 18, Issue:1

    Topics: Acetylcholine; Animals; Atropine; Binding, Competitive; Cerebral Cortex; Guinea Pigs; In Vitro Techniques; Male; Muscle, Smooth; Parasympatholytics; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Thiazepines

1987