bruceine d has been researched along with gemcitabine in 2 studies
| Studies (bruceine d) | Trials (bruceine d) | Recent Studies (post-2010) (bruceine d) | Studies (gemcitabine) | Trials (gemcitabine) | Recent Studies (post-2010) (gemcitabine) |
|---|---|---|---|---|---|
| 31 | 0 | 22 | 12,523 | 3,208 | 6,923 |
| Protein | Taxonomy | bruceine d (IC50) | gemcitabine (IC50) |
|---|---|---|---|
| Chain A, DEOXYNUCLEOSIDE KINASE | Drosophila melanogaster (fruit fly) | 0.76 | |
| Equilibrative nucleoside transporter 1 | Homo sapiens (human) | 0.19 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, LH; Leung, PS; Liang, J; Lin, ZX; Liu, L; Zhao, M | 1 |
| Cheuk, W; Cho, WCS; Huang, QH; Li, Y; Lin, ZX; Xian, YF; Xu, HX; Yang, W; Zhang, J | 1 |
2 other study(ies) available for bruceine d and gemcitabine
| Article | Year |
|---|---|
Involvement of the mitochondrial pathway in bruceine D-induced apoptosis in Capan-2 human pancreatic adenocarcinoma cells.
Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Apoptosis; Brucea; Camptothecin; Caspase 3; Caspase 9; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Deoxycytidine; DNA Damage; Drugs, Chinese Herbal; Gemcitabine; Hepatocytes; Humans; Membrane Potential, Mitochondrial; Mitochondria; Pancreatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Quassins; Stem Cells | 2012 |
Brucein D augments the chemosensitivity of gemcitabine in pancreatic cancer via inhibiting the Nrf2 pathway.
Topics: Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Deoxycytidine; Female; Gemcitabine; Humans; Mice; Mice, Nude; NF-E2-Related Factor 2; Pancreatic Neoplasms; Quassins; Survival Analysis; Transfection | 2022 |