brompheniramine has been researched along with zimeldine in 122 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 119 (97.54) | 18.7374 |
1990's | 1 (0.82) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 2 (1.64) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
Högberg, T; Renyi, AL; Ross, SB; Ulff, B | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
Eneroth, P; Ross, SB; Syvälahti, E | 1 |
Johansson, F; von Knorring, L | 2 |
Calil, HM; Extein, I; Goodwin, FK; Potter, WZ; Zavadil, AP | 1 |
Erixson, E; Westerlund, D | 1 |
Cott, JM; Hall, H; Ogren, SO | 1 |
Czuczwar, SJ; Kleinrok, Z; Turski, L; Turski, W | 1 |
Harvengt, C | 1 |
Maj, J; Rogóz, Z; Skuza, G | 1 |
Johansson, F; Sedvall, G; Terenius, L; von Knorring, L | 1 |
Hall, H; Renyi, AL; Ross, SB; Westerlund, D | 1 |
Aberg-Wistedt, A; Jostell, KG; Ross, SB; Sjöquist, B | 1 |
Ask, AL; Fagervall, I; Ross, SB | 1 |
Kiloh, LG; Moore, G | 1 |
McAuley, R; Montgomery, DB; Montgomery, SA; Rani, SJ; Roy, D | 3 |
Bush, D; Georgotas, A; Gershon, S; Newton, R | 1 |
Georgotas, A; Gershon, S; Krakowski, M | 1 |
Fagan, D; Scott, DB; Tiplady, B | 1 |
Crome, P | 1 |
Calil, HM; Karoum, F; Kopin, IJ; Linnoila, M; Potter, WZ | 1 |
Broadbent, J; Jones, RS | 1 |
Lehtinen, V; Salminen, J; Syvälahti, E | 1 |
Aberg-Wistedt, A | 2 |
Campbell, LM; McLaren, EH; Sommerville, JM; Watson, JM | 1 |
Avery, GS; Brogden, RN; Carmine, AA; Heel, RC; Morley, PA; Speight, TM | 1 |
Prakash, R | 1 |
Baumann, PA; Jackel, J; Maître, L; Waldmeier, PC | 1 |
Arnold, H; Hörmann, E; Schaffler, K | 1 |
Clarke, IM | 1 |
Carlsson, A | 1 |
Hede, AR; Post, C | 1 |
Kupfer, D | 1 |
Elton, RA; Loudon, JB; Tiplady, B | 1 |
Hall, H; Lindbom, LO; Malatray, J; Ogren, SO | 1 |
Fahlesson, P; Lundgren, M; Nilsson, LM; Osterlind, A; Paulsen, O; Sellin, M | 1 |
O'Connor, M; Pettiford, J | 1 |
Maj, J; Pawłowski, L; Ruczyńska, J | 1 |
Karoum, F; Linnoila, M; Potter, WZ; Rosenthal, N | 1 |
Gershon, S; Kelwala, S; Stanley, M | 1 |
Feighner, JP | 1 |
Burrows, GD; Davies, BM; Marriott, PF; McIntyre, IM; Moore, RG; Norman, TR | 1 |
Aberg-Wistedt, A; Ross, SB | 1 |
Ballinger, BR; Feely, J | 1 |
Buchsbaum, MS; Linnoila, M; Rudorfer, MV; Weingartner, H | 1 |
Karlsson, R; Lindholm, CG; Sköld, A | 1 |
Gankina, EM; Maĭsov, NI | 1 |
Shelekhov, SL; Val'dman, AV | 1 |
Hill, SY; Kupfer, DJ; Reyes, RB | 1 |
Behrnetz, S; Bush, DF; Claghorn, J; Gershon, S; Goldstein, BJ; Huitfeldt, B | 1 |
Bratfos, O; Bratlid, T; Haug, JO; Lingjaerde, O | 1 |
Karoum, F; Linnoila, M; Potter, WZ | 1 |
Janowsky, A; Mishra, R; Sulser, F | 1 |
Agnati, LF; Andersson, K; Eneroth, P; Fuxe, K; Holm, AC; Ogren, SO | 1 |
De Montigny, C | 1 |
Agnati, LF; Andersson, K; Eneroth, P; Fuxe, K; Ogren, SO | 1 |
Hall, H; Ogren, SO; Ross, SB | 1 |
Scuvée-Moreau, JJ; Svensson, TH | 1 |
Andersson, S; Thoren, P; Yao, T | 1 |
Agnati, LF; Calza, L; Fuxe, K; Ogren, SO | 1 |
Bymaster, FP; Reid, LR; Threlkeld, PG; Wong, DT | 1 |
Blier, P; De Montigny, C | 1 |
Doerr, HG; Holsboer, F; Müller, OA; Sippell, WG; Winter, K | 1 |
Danchev, ND; Rozhanets, VV; Rusakov, DIu; Val'dman, AV | 1 |
Brown, D; Lundström, J; Meyer, M; Scott, DB; Scott, DH; Westerlund, D | 1 |
Holm, AC; Ogren, SO | 1 |
Bockhardt, H; Lüllmann-Rauch, R | 1 |
Holm, AC; Ogren, SO; Renyi, AL; Ross, SB | 1 |
Bush, D; Georgotas, A; Gershon, S; Mann, J | 2 |
Best, J; Cox, J; Evans, L; Moore, G | 1 |
Carlsson, A; Persson, R; Wålinder, J; Wallin, L | 1 |
Connor, JD; Damiano, BP; Drust, EG; Sloviter, RS | 1 |
Amit, Z; Bourque, C; Brown, ZW; Ogren, SO; Rockman, GE | 1 |
Simpson, RJ; Skegg, DC; Tiplady, B | 1 |
Gebhart, GF; Lorens, SA | 1 |
Leonard, BE | 1 |
Montgomery, SA | 1 |
Montgomery, SA; Tiplady, B | 1 |
Hansen, LB; Hvidberg, EF; Larsen, NE; Thomsen, IS; Vestergård, P | 1 |
Bertilsson, L; Siwers, B; Tuck, JR | 1 |
Lawton, DJ; Simpson, RJ; Tiplady, B; Watt, MH | 1 |
Burgess, CD; Montgomery, DB; Montgomery, SA; Wadsworth, J | 1 |
Hall, H; Holm, AC; Ogren, SO; Renyi, AL; Ross, SB | 1 |
Calil, HM; Extein, I; Gold, PW; Goodwin, FK; Potter, WZ; Wehr, TA | 1 |
Carlsson, A; Persson, R; Wålinder, J | 1 |
d'Elia, G; Hällström, T; Nyström, C; Ottosson, JO | 1 |
Aberg, A | 1 |
Holmberg, G | 1 |
Filler, W; Ranft, W; Schenk, GK; Zerbin, D | 1 |
Holmberg, G; Koczkas, S; Wedin, L | 1 |
Evans, L; Moore, G | 1 |
Forsberg, T; Lindbom, LO | 1 |
Brown, D; Christie, JE | 1 |
Björnsson, G; Dehlin, O; Lundström, J | 1 |
Clarke, P; Haythorne, JM; Stevenson, IH; Swift, CG | 1 |
Ashcroft, GW; Loudon, JB; Tiplady, B; Waddell, JL | 1 |
Tiplady, B; Watson, JM | 1 |
Blier, P; Caillé, G; de Montigny, C; Kouassi, E | 1 |
de Paulis, T; Gosztonyi, T; Högberg, T; Lundström, J | 1 |
Claghorn, JL; Mathew, RJ | 1 |
Calil, HM; Extein, I; Goodwin, FK; Muscettola, G; Potter, WZ | 1 |
Chaturvedi, S; Love, BL; Moore, RG; Thomas, J | 1 |
Aberg-Wistedt, A; Jostell, KG; Ross, SB; Westerlund, D | 1 |
Klimek, V; Kordecka-Magiera, A; Maj, J; Mogilnicka, E | 1 |
Mörnstad, H; von Knorring, L | 1 |
Nicklasson, M; Nyqvist, H | 1 |
Archer, T; Fuxe, K; Hall, H; Holm, AC; Köhler, C; Ogren, SO | 1 |
Amit, Z; Brown, ZW; Ogren, SO; Rockman, G; Selvaggi, N; Sutherland, A | 1 |
Calil, HM; Cowdry, RW; Jostell, KG; Potter, WZ | 1 |
von Knorring, L | 1 |
Gawell, L; Hall, H; Ogren, SO; Ross, S | 1 |
Cashman, JR; Celestial, JR; Leach, A; Newdoll, J; Park, SB | 1 |
8 review(s) available for brompheniramine and zimeldine
Article | Year |
---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Antidepressant overdosage.
Topics: Antidepressive Agents; Antidepressive Agents, Tricyclic; Brompheniramine; Flupenthixol; Humans; Iprindole; Lithium; Mianserin; Monoamine Oxidase Inhibitors; Nomifensine; Orphenadrine; Parasympatholytics; Pyridoxine; Trazodone; Tryptophan; Viloxazine; Zimeldine | 1982 |
Zimelidine: a review of its pharmacological properties and therapeutic efficacy in depressive illness.
Topics: Antidepressive Agents; Body Weight; Brompheniramine; Central Nervous System; Depressive Disorder; Drug Interactions; Endocrine Glands; Hemodynamics; Humans; Kinetics; Parasympatholytics; Pyridines; Zimeldine | 1982 |
5-HT uptake inhibitors: psychopharmacological and neurobiochemical criteria of selectivity.
Topics: Acetylcholine; Animals; Antidepressive Agents; Behavior, Animal; Brain Chemistry; Brompheniramine; Catecholamines; Corpus Striatum; Monoamine Oxidase Inhibitors; Serotonin Antagonists; Zimeldine | 1982 |
History of antidepressants: successes and failures.
Topics: Albuterol; Animals; Antidepressive Agents; Brompheniramine; Bupropion; Clinical Trials as Topic; Depressive Disorder; Dibenzocycloheptenes; Drug Evaluation, Preclinical; Fluoxetine; History, 20th Century; Humans; Monoamine Oxidase Inhibitors; Propiophenones; Psychopharmacology; Receptors, Adrenergic; Receptors, Serotonin; Trazodone; Zimeldine | 1983 |
The new generation of antidepressants.
Topics: Alprazolam; Antidepressive Agents; Antidepressive Agents, Tricyclic; Benzodiazepines; Brompheniramine; Bupropion; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Fluoxetine; Humans; Monoamine Oxidase Inhibitors; Propiophenones; Zimeldine | 1983 |
Pharmacological properties of some "second generation" antidepressant drugs.
Topics: Animals; Antidepressive Agents; Brompheniramine; Depression; Electroconvulsive Therapy; Humans; Mianserin; Nomifensine; Trazodone; Zimeldine | 1980 |
Maprotiline, nomifensine, mianserin, zimelidine: a review of antidepressant efficacy in in-patients.
Topics: Antidepressive Agents; Brompheniramine; Clinical Trials as Topic; Depression; Humans; Maprotiline; Mianserin; Nomifensine; Psychiatric Status Rating Scales; Zimeldine | 1980 |
43 trial(s) available for brompheniramine and zimeldine
Article | Year |
---|---|
Visual evoked potentials as a predictor of reported side effects during a trial of zimelidine vs. placebo in chronic pain patients.
Topics: Adult; Aged; Brompheniramine; Double-Blind Method; Evoked Potentials; Female; Humans; Male; Middle Aged; Pain, Intractable; Photic Stimulation; Pyridines; Serotonin Antagonists; Visual Perception; Zimeldine | 1979 |
Comparative pharmacokinetics of zimelidine and desipramine in man following acute and chronic administration.
Topics: Adolescent; Adult; Affective Disorders, Psychotic; Aged; Antidepressive Agents; Brompheniramine; Desipramine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Pyridines; Zimeldine | 1979 |
An open trial of zimelidine in patients with endogenous depression.
Topics: Aged; Antidepressive Agents; Brompheniramine; Clinical Trials as Topic; Depressive Disorder; Female; Headache; Humans; Male; Middle Aged; Personality Inventory; Pyridines; Zimeldine | 1982 |
Profile of antidepressant action of zimelidine and norzimelidine compared with amitriptyline.
Topics: Adult; Amitriptyline; Antidepressive Agents; Brompheniramine; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Female; Humans; Male; Pyridines; Zimeldine | 1982 |
Clinical evaluation of two new antidepressants.
Topics: Adolescent; Adult; Aged; Antidepressive Agents; Brompheniramine; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Female; Humans; Imipramine; Male; Middle Aged; Piperazines; Psychiatric Status Rating Scales; Pyridines; Trazodone; Zimeldine | 1982 |
Controlled trial of zimelidine, a 5-HT reuptake inhibitor, for treatment of depression.
Topics: Adolescent; Adult; Aged; Amitriptyline; Brompheniramine; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Female; Humans; Male; Middle Aged; Placebos; Pyridines; Serotonin Antagonists; Zimeldine | 1982 |
Effects of amitriptyline and zimelidine in combination with ethanol.
Topics: Adult; Amitriptyline; Antidepressive Agents; Brompheniramine; Drug Interactions; Ethanol; Humans; Male; Motor Skills; Pyridines; Time Factors; Zimeldine | 1982 |
Alteration of norepinephrine metabolism with desipramine and zimelidine in depressed patients.
Topics: Antidepressive Agents; Brain; Brompheniramine; Depressive Disorder; Desipramine; Female; Humans; Male; Methoxyhydroxyphenylglycol; Middle Aged; Norepinephrine; Normetanephrine; Pyridines; Vanilmandelic Acid; Zimeldine | 1982 |
A double-blind comparison of zimelidine and amitriptyline in depressive out-patients.
Topics: Adult; Ambulatory Care; Amitriptyline; Antidepressive Agents; Brompheniramine; Clinical Trials as Topic; Depressive Disorder; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Pyridines; Zimeldine | 1982 |
A double-blind study of zimelidine, a serotonin uptake inhibitor, and desipramine, a noradrenaline uptake inhibitor, in endogenous depression. I. Clinical findings.
Topics: Adult; Aged; Antidepressive Agents; Bipolar Disorder; Brompheniramine; Depressive Disorder; Desipramine; Double-Blind Method; Female; Humans; Male; Middle Aged; Norepinephrine; Psychiatric Status Rating Scales; Pyridines; Serotonin; Zimeldine | 1982 |
Evaluation of role of the biogenic amines in affective illness: a clinical strategy.
Topics: Antidepressive Agents; Biogenic Amines; Brompheniramine; Clinical Trials as Topic; Desipramine; Humans; Mood Disorders; Zimeldine | 1982 |
Comparison between zimelidine and desipramine in endogenous depression. A cross-over study.
Topics: Antidepressive Agents; Bipolar Disorder; Brompheniramine; Depressive Disorder; Desipramine; Double-Blind Method; Female; Humans; Male; Middle Aged; Norepinephrine; Pyridines; Serotonin; Zimeldine | 1982 |
[Vigilance behavior in interaction of the serotonin-selective antidepressant zimelidine and parenterally administered ethanol].
Topics: Adult; Attention; Brompheniramine; Double-Blind Method; Drug Interactions; Electrooculography; Ethanol; Humans; Male; Pyridines; Respiration; Saccades; Zimeldine | 1982 |
Zimelidine: a second generation antidepressant. A report from the general practitioner research group.
Topics: Adolescent; Adult; Aged; Amitriptyline; Brompheniramine; Clinical Trials as Topic; Depressive Disorder; Female; Humans; Male; Middle Aged; Pyridines; Sleep Initiation and Maintenance Disorders; Zimeldine | 1982 |
History of antidepressants: successes and failures.
Topics: Albuterol; Animals; Antidepressive Agents; Brompheniramine; Bupropion; Clinical Trials as Topic; Depressive Disorder; Dibenzocycloheptenes; Drug Evaluation, Preclinical; Fluoxetine; History, 20th Century; Humans; Monoamine Oxidase Inhibitors; Propiophenones; Psychopharmacology; Receptors, Adrenergic; Receptors, Serotonin; Trazodone; Zimeldine | 1983 |
The new generation of antidepressants.
Topics: Alprazolam; Antidepressive Agents; Antidepressive Agents, Tricyclic; Benzodiazepines; Brompheniramine; Bupropion; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Fluoxetine; Humans; Monoamine Oxidase Inhibitors; Propiophenones; Zimeldine | 1983 |
Zimelidine: a placebo-controlled trial in depression.
Topics: Adolescent; Adult; Aged; Antidepressive Agents; Blood Pressure; Brompheniramine; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Female; Heart Rate; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Pyridines; Zimeldine | 1983 |
Inhibitors of serotonin and noradrenaline uptake in human plasma after withdrawal of zimelidine and clomipramine treatment.
Topics: Adult; Blood Platelets; Brompheniramine; Carbon Radioisotopes; Clomipramine; Depression; Female; Humans; Hypothalamus; Male; Middle Aged; Norepinephrine; Pyridines; Serotonin; Synaptosomes; Tritium; Zimeldine | 1983 |
A double-blind evaluation of zimelidine in comparison to placebo and amitriptyline in patients with major depressive disorder.
Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents; Brompheniramine; Depressive Disorder; Double-Blind Method; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Pyridines; Zimeldine | 1983 |
A double-blind comparison of zimelidine and desipramine in endogenous depression.
Topics: Adolescent; Adult; Aged; Brompheniramine; Depressive Disorder; Desipramine; Double-Blind Method; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Pyridines; Serotonin; Zimeldine | 1983 |
Effects of antidepressant treatments on dopamine turnover in depressed patients.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Antidepressive Agents; Bipolar Disorder; Brompheniramine; Clorgyline; Depressive Disorder; Desipramine; Dopamine; Electroconvulsive Therapy; Female; Homovanillic Acid; Humans; Male; Middle Aged; Zimeldine | 1983 |
Effect of serotonin uptake inhibition by zimelidine on hypothalamic-pituitary-adrenal activity.
Topics: Adrenocorticotropic Hormone; Adult; Biological Transport; Brompheniramine; Humans; Hypothalamo-Hypophyseal System; Male; Pituitary-Adrenal System; Placebos; Pyridines; Serotonin; Serotonin Antagonists; Zimeldine | 1983 |
A clinical trial of zimelidine in depression.
Topics: Adult; Antidepressive Agents; Brompheniramine; Clinical Trials as Topic; Depression; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Pyridines; Zimeldine | 1980 |
Potentiation of the effect of antidepressant drugs by tryptophan.
Topics: Antidepressive Agents; Brompheniramine; Clinical Trials as Topic; Depression; Double-Blind Method; Drug Synergism; Humans; Pyridines; Sleep Wake Disorders; Tryptophan; Zimeldine | 1980 |
Event recording in a clinical trial of a new medicine.
Topics: Adult; Appetite; Body Weight; Brompheniramine; Clinical Trials as Topic; Data Collection; Double-Blind Method; Female; Humans; Pyridines; Sleep Initiation and Maintenance Disorders; Zimeldine | 1980 |
Maprotiline, nomifensine, mianserin, zimelidine: a review of antidepressant efficacy in in-patients.
Topics: Antidepressive Agents; Brompheniramine; Clinical Trials as Topic; Depression; Humans; Maprotiline; Mianserin; Nomifensine; Psychiatric Status Rating Scales; Zimeldine | 1980 |
Changes in the augmenter-reducer tendency and in pain measures as a result of treatment with a serotonin-reuptake inhibitor--zimelidine.
Topics: Adult; Aged; Brompheniramine; Evoked Potentials; Female; Humans; Male; Middle Aged; Neural Pathways; Pain, Intractable; Photic Stimulation; Pyridines; Sensory Thresholds; Serotonin; Zimeldine | 1980 |
Effect of zimelidine, a new antidepressant, on appetite and body weight.
Topics: Adult; Antidepressive Agents; Appetite Depressants; Brompheniramine; Double-Blind Method; Female; Humans; Middle Aged; Obesity; Patient Compliance; Pyridines; Zimeldine | 1981 |
Zimelidine vs maprotiline in depressed outpatients. A preliminary report.
Topics: Adult; Aged; Anthracenes; Antidepressive Agents; Brompheniramine; Depression; Depressive Disorder; Electrocardiography; Female; Humans; Male; Maprotiline; Middle Aged; Psychiatric Status Rating Scales; Pyridines; Zimeldine | 1981 |
Controlled cross-over study of a 5-HT uptake inhibiting and an NA uptake inhibiting antidepressant.
Topics: Antidepressive Agents; Brompheniramine; Depressive Disorder; Desipramine; Female; Humans; Male; Norepinephrine; Psychiatric Status Rating Scales; Serotonin Antagonists; Zimeldine | 1981 |
Critical flicker fusion (CFF) test for sedative effect of antidepressants.
Topics: Adult; Amitriptyline; Antidepressive Agents; Arousal; Brompheniramine; Doxepin; Female; Flicker Fusion; Humans; Hypnotics and Sedatives; Imipramine; Male; Nomifensine; Zimeldine | 1981 |
Double-blind comparisons of a selective serotonin reuptake inhibitor, zimelidine, and placebo on quantified EEG parameters and psychological variables.
Topics: Adult; Attention; Brain; Brompheniramine; Double-Blind Method; Electroencephalography; Emotions; Flicker Fusion; Humans; Male; Placebos; Pyridines; Reaction Time; Serotonin Antagonists; Zimeldine | 1981 |
A double blind comparison of zimelidine and amitriptyline in endogenous depression.
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents; Brompheniramine; Depressive Disorder; Double-Blind Method; Electrocardiography; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Pyridines; Zimeldine | 1981 |
Comparison of the cardiovascular effects of amitriptyline and zimelidine using thoracic impedance cardiography.
Topics: Amitriptyline; Antidepressive Agents; Brompheniramine; Cardiography, Impedance; Depression; Double-Blind Method; Female; Hemodynamics; Humans; Male; Plethysmography, Impedance; Psychiatric Status Rating Scales; Pyridines; Zimeldine | 1981 |
Zimelidine and amitriptyline in the treatment of depressive illness in general practice.
Topics: Adult; Amitriptyline; Antidepressive Agents; Brompheniramine; Depressive Disorder; Family Practice; Humans; Middle Aged; Psychiatric Status Rating Scales; Pyridines; Zimeldine | 1981 |
Zimelidine: comparison of different dosage regimes in general practice.
Topics: Adult; Aged; Antidepressive Agents; Brompheniramine; Depressive Disorder; Family Practice; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Pyridines; Zimeldine | 1981 |
Clinical trials with new bicyclic and tetracyclic compounds: zimelidine and maprotiline [proceedings].
Topics: Animals; Anthracenes; Brompheniramine; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Humans; Maprotiline; Pyridines; Rats; Zimeldine | 1981 |
Crossover study of zimelidine and desipramine in depression: evidence for amine specificity [proceedings].
Topics: Brompheniramine; Clinical Trials as Topic; Depressive Disorder; Desipramine; Double-Blind Method; Humans; Pyridines; Time Factors; Zimeldine | 1981 |
Effects of zimelidine and desipramine on serotonin and noradrenaline uptake mechanisms in relation to plasma concentrations and to therapeutic effects during treatment of depression.
Topics: Animals; Antidepressive Agents; Blood Platelets; Brompheniramine; Depressive Disorder; Desipramine; Female; Humans; In Vitro Techniques; Male; Norepinephrine; Pyridines; Rats; Serotonin; Synaptosomes; Zimeldine | 1981 |
Qualitative changes in saliva composition after short-term administration of imipramine and zimelidine in healthy volunteers.
Topics: Adult; Brompheniramine; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Imipramine; Male; Pyridines; Random Allocation; Saliva; Salivation; Zimeldine | 1981 |
An examination of possible interactions between zimelidine, a serotonin uptake inhibitor, and ethanol ingested conjointly in human subjects.
Topics: Adolescent; Adult; Alcohol Drinking; Blood Pressure; Brompheniramine; Drug Interactions; Electrolytes; Ethanol; Heart Rate; Humans; Male; Middle Aged; Motor Skills; Pyridines; Reaction Time; Serotonin; Serotonin Antagonists; Zimeldine | 1981 |
Zimelidine and norzimelidine protein binding measured by equilibrium dialysis and cerebrospinal fluid.
Topics: Adolescent; Adult; Aged; Antidepressive Agents; Brompheniramine; Female; Humans; Male; Middle Aged; Orosomucoid; Protein Binding; Pyridines; Zimeldine | 1982 |
Changes in saliva secretion and accommodation width during short-term administration of imipramine and zimelidine in healthy volunteers.
Topics: Accommodation, Ocular; Adult; Antidepressive Agents; Brompheniramine; Female; Humans; Imipramine; Male; Parasympathetic Nervous System; Pyridines; Salivation; Xerostomia; Zimeldine | 1981 |
74 other study(ies) available for brompheniramine and zimeldine
Article | Year |
---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Synthesis of pyridylallylamines related to zimelidine and their inhibition of neuronal monoamine uptake.
Topics: Animals; Biogenic Amines; Brain; Brompheniramine; Chemical Phenomena; Chemistry; In Vitro Techniques; Male; Mice; Molecular Conformation; Neurons; Norepinephrine; Pyridines; Serotonin; Structure-Activity Relationship; Zimeldine | 1981 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
Acute effects of zimelidine and alaproclate, two inhibitors of serotonin uptake, on neuroendocrine function.
Topics: Adult; Alanine; Blood Platelets; Brompheniramine; Dose-Response Relationship, Drug; Follicle Stimulating Hormone; Growth Hormone; Humans; Hydrocortisone; In Vitro Techniques; Luteinizing Hormone; Male; Pituitary Hormones, Anterior; Prolactin; Pyridines; Serotonin; Serotonin Antagonists; Thyrotropin; Zimeldine | 1979 |
Reversed-phase chromatography of zimelidine and similar dibasic amines. I. Analysis in biological material.
Topics: Animals; Antidepressive Agents; Brompheniramine; Chromatography, Liquid; Humans; Pyridines; Rats; Zimeldine | 1979 |
Sedative/anxiolytic effects of antidepressants in animals.
Topics: Aggression; Animals; Anti-Anxiety Agents; Antidepressive Agents; Brompheniramine; Humans; Hypnotics and Sedatives; Male; Mice; p-Chloroamphetamine; Serotonin; Zimeldine | 1981 |
Effect of trazodone, mianserin, iprindole and zimelidine on wet dog shakes produced by carbachol in rats.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brompheniramine; Carbachol; Iprindole; Male; Mianserin; Rats; Rats, Inbred Strains; Trazodone; Zimeldine | 1981 |
[Recently registered drugs].
Topics: Adrenergic beta-Agonists; Amitriptyline; Antidepressive Agents; Belgium; Brompheniramine; Humans; Legislation, Drug; Practolol; Prenalterol; Pyridines; Zimeldine | 1982 |
5-Hydroxytryptamine uptake inhibitors antagonize the antireserpine effects of noradrenaline uptake inhibitors.
Topics: Animals; Brompheniramine; Citalopram; Fluvoxamine; Male; Mice; Motor Activity; Norepinephrine; Oximes; Propylamines; Reserpine; Serotonin Antagonists; Tetrabenazine; Zimeldine | 1983 |
Changes in endorphins and 5-hydroxyindoleacetic acid in cerebrospinal fluid as a result of treatment with a serotonin reuptake inhibitor (zimelidine) in chronic pain patients.
Topics: Adult; Brompheniramine; Double-Blind Method; Endorphins; Female; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Pain, Intractable; Pyridines; Zimeldine | 1980 |
Effects of zimelidine on serotoninergic and noradrenergic neurons after repeated administration in the rat.
Topics: Animals; Brain; Brompheniramine; Hydroxyindoleacetic Acid; In Vitro Techniques; Male; Norepinephrine; Pyridines; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; Receptors, Serotonin; Serotonin; Zimeldine | 1981 |
A double-blind study of zimelidine, a serotonin uptake inhibitor, and desipramine, a noradrenaline uptake inhibitor, in endogenous depression. II. Biochemical findings.
Topics: Adult; Aged; Animals; Antidepressive Agents; Blood Platelets; Brompheniramine; Depressive Disorder; Desipramine; Double-Blind Method; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Hypothalamus; Male; Methoxyhydroxyphenylglycol; Middle Aged; Norepinephrine; Pyridines; Rats; Serotonin; Synaptosomes; Zimeldine | 1982 |
Evidence for a selective inhibition by FLA 336(+) of the monoamine oxidase in serotonergic neurones in the rat brain.
Topics: Animals; Brain; Brompheniramine; Hydroxyindoleacetic Acid; In Vitro Techniques; Male; Monoamine Oxidase Inhibitors; Neurons; Phenelzine; Phenethylamines; Rats; Rats, Inbred Strains; Serotonin; Synaptosomes; Zimeldine | 1982 |
Differential effects of fluoxetine and zimelidine on the uptake of 5-hydroxytryptamine and tryptamine by cortical slices and on responses of cortical neurones to stimulation of the nucleus raphe medianus.
Topics: Animals; Brompheniramine; Cerebral Cortex; Electric Stimulation; Fluoxetine; Male; Neurons; Propylamines; Pyridines; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin; Tryptamines; Zimeldine | 1982 |
Severe headache and disturbed liver function during treatment with zimelidine.
Topics: Adult; Antidepressive Agents; Brompheniramine; Female; Headache; Humans; Liver; Liver Function Tests; Male; Pyridines; Zimeldine | 1982 |
Severe headache and disturbed liver function during treatment with zimelidine.
Topics: Brompheniramine; Chemical and Drug Induced Liver Injury; Headache; Humans; Pyridines; Serotonin Antagonists; Zimeldine | 1982 |
Recent observations on new potential and established antidepressant drugs.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aged; Animals; Antidepressive Agents; Brain; Brompheniramine; Dementia; Depressive Disorder; Humans; Male; Rats; Receptors, Dopamine; Receptors, Serotonin; Research; Serotonin; Sexual Behavior, Animal; Structure-Activity Relationship; Tetrahydronaphthalenes; Zimeldine | 1982 |
Uptake of zimelidine and inhibition of uptake of 5-hydroxytryptamine in the isolated, ventilated and perfused rat lung.
Topics: Animals; Biological Transport; Brompheniramine; Female; In Vitro Techniques; Lidocaine; Lung; Male; Perfusion; Pyridines; Rats; Rats, Inbred Strains; Serotonin; Zimeldine | 1982 |
Zimelidine: a new antidepressive.
Topics: Antidepressive Agents; Brompheniramine; Humans; Pyridines; Zimeldine | 1982 |
Interaction of EEG sleep, antidepressants, and affective disease.
Topics: Amitriptyline; Antidepressive Agents; Brompheniramine; Depressive Disorder; Desipramine; Electroencephalography; Humans; Sleep; Sleep, REM; Zimeldine | 1982 |
Coding and analysis of spontaneously reported symptoms in clinical trials.
Topics: Amitriptyline; Brompheniramine; Clinical Trials as Topic; Depressive Disorder; Humans; Statistics as Topic; Zimeldine | 1983 |
Cardiovascular and anticholinergic effects of zimelidine.
Topics: Amitriptyline; Animals; Antidepressive Agents; Blood Pressure; Brompheniramine; Clomipramine; Dogs; Dose-Response Relationship, Drug; Female; Heart Rate; Hemodynamics; Imipramine; Male; Pyridines; Receptors, Cholinergic; Zimeldine | 1982 |
[Adverse effects and zimelidine therapy. Headache, muscle pain and liver involvement--a new disease entity in zimelidine therapy].
Topics: Adult; Antidepressive Agents; Brompheniramine; Female; Headache; Humans; Liver; Muscles; Pain; Pyridines; Zimeldine | 1983 |
Zimelidine in chronic suicidal behaviour.
Topics: Adult; Antidepressive Agents; Brompheniramine; Humans; Male; Pyridines; Serotonin; Suicide, Attempted; Zimeldine | 1982 |
Zimelidine and clomipramine: different influence on fenfluramine but not p-chloroamphetamine-induced pharmacological effects.
Topics: Amphetamines; Animals; Body Temperature; Brompheniramine; Clomipramine; Drug Interactions; Fenfluramine; Male; Models, Neurological; p-Chloroamphetamine; Pyridines; Rats; Rats, Inbred Strains; Reflex; Serotonin; Zimeldine | 1980 |
Electroconvulsive treatment and lithium carbonate. Their effects on norepinephrine metabolism in patients with primary, major depressions.
Topics: Brompheniramine; Clorgyline; Depressive Disorder; Desipramine; Electroconvulsive Therapy; Female; Humans; Lithium; Lithium Carbonate; Male; Methoxyhydroxyphenylglycol; Middle Aged; Norepinephrine; Normetanephrine; Vanilmandelic Acid; Zimeldine | 1983 |
Antidepressants.
Topics: Antidepressive Agents; Antidepressive Agents, Tricyclic; Brompheniramine; Humans; Maprotiline; Mianserin; Nomifensine; Trazodone; Viloxazine; Zimeldine | 1983 |
Effects of serotonin on memory impairments produced by ethanol.
Topics: Adult; Brompheniramine; Ethanol; Humans; Learning; Male; Memory; Memory Disorders; Mental Recall; Serotonin; Serotonin Antagonists; Zimeldine | 1983 |
[Further case of zimelidine adverse effects].
Topics: Brompheniramine; Female; Humans; Middle Aged; Pyridines; Zimeldine | 1983 |
[Side effects of a modified type of zimelidine therapy. A review of current reports].
Topics: Adult; Aged; Antidepressive Agents; Brompheniramine; Cimetidine; Drug Interactions; Female; Humans; Male; Middle Aged; Pyridines; Zimeldine | 1983 |
[Mechanism of the inhibiting effect of atypical antidepressants and psychostimulants on the synaptosomal uptake of monoamines].
Topics: Amphetamine; Animals; Antidepressive Agents; Brompheniramine; Cerebral Cortex; Cocaine; Dopamine; Imipramine; Norepinephrine; Rats; Serotonin; Synaptosomes; Viloxazine; Zimeldine | 1983 |
[Effect of serotoninergic substances on escape behavior in acute stress situations].
Topics: 5-Hydroxytryptophan; Animals; Antidepressive Agents; Brompheniramine; Cyproheptadine; Escape Reaction; Humans; Male; Piperazines; Piperidines; Quipazine; Rats; Rats, Inbred Strains; Serotonin; Stress, Psychological; Tranquilizing Agents; Trazodone; Zimeldine | 1983 |
Effects of acute doses of zimelidine on REM sleep in rats.
Topics: Animals; Antidepressive Agents; Brompheniramine; Dose-Response Relationship, Drug; Male; Muridae; Pyridines; Reaction Time; Sleep, REM; Zimeldine | 1983 |
Action of mianserin and zimelidine on the norepinephrine receptor coupled adenylate cyclase system in brain: subsensitivity without reduction in beta-adrenergic receptor binding.
Topics: Adenylyl Cyclases; Animals; Brain; Brompheniramine; Dibenzazepines; Dihydroalprenolol; Isoproterenol; Kinetics; Male; Mianserin; Pyridines; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; Zimeldine | 1980 |
Long-term treatment with zimelidine leads to a reduction in 5-hydroxytryptamine neurotransmission within the central nervous system of the mouse and rat.
Topics: Animals; Antidepressive Agents; Binding Sites; Brain; Brompheniramine; Kinetics; Lysergic Acid Diethylamide; Male; Mice; Pyridines; Rats; Receptors, Serotonin; Serotonin; Synaptic Transmission; Time Factors; Zimeldine | 1981 |
Enhancement of the 5-HT neurotransmission by antidepressant treatments.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Brompheniramine; Circadian Rhythm; Depression; Electroconvulsive Therapy; Emotions; Humans; Lithium; Models, Psychological; Neurons; Raphe Nuclei; Receptors, Serotonin; Serotonin; Synaptic Transmission; Zimeldine | 1981 |
The effects of subchronic antidepressant drug treatment on the secretion of adenohypophyseal hormones and of corticosterone in the male rat.
Topics: Animals; Antidepressive Agents; Brompheniramine; Corticosterone; Desipramine; Male; Norepinephrine; Pituitary Hormones, Anterior; Rats; Rats, Inbred Strains; Serotonin; Synaptic Transmission; Time Factors; Zimeldine | 1982 |
Effects of zimelidine on various transmitter systems in the brain.
Topics: Animals; Brain; Brompheniramine; Male; Mice; Norepinephrine; Pyridines; Rats; Receptors, Adrenergic, beta; Receptors, Cell Surface; Receptors, Serotonin; Serotonin; Synaptic Transmission; Time Factors; Zimeldine | 1982 |
Sensitivity in vivo of central alpha 2- and opiate receptors after chronic treatment with various antidepressants.
Topics: Animals; Antidepressive Agents; Brompheniramine; Chlorpromazine; Clomipramine; Clonidine; Desipramine; Evoked Potentials; Imipramine; Iprindole; Locus Coeruleus; Male; Mianserin; Morphine; Neural Inhibition; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Opioid; Zimeldine | 1982 |
Long-lasting cardiovascular depressor response following sciatic stimulation in spontaneously hypertensive rats. Evidence for the involvement of central endorphin and serotonin systems.
Topics: 5-Hydroxytryptophan; Animals; Blood Pressure; Brompheniramine; Dexamethasone; Electric Stimulation; Endorphins; Heart; Heart Rate; Hypertension; Naloxone; Neural Inhibition; Nociceptors; Rats; Rats, Inbred Strains; Sciatic Nerve; Serotonin; Synaptic Transmission; Zimeldine | 1982 |
Evidence for stabilization of cortical 5HT neurotransmission by chronic treatment with antidepressant drugs: induction of a high and low affinity component in 3H-5HT binding sites.
Topics: Animals; Antidepressive Agents; Binding Sites; Brompheniramine; Cerebral Cortex; Desipramine; Imipramine; Male; Rats; Rats, Inbred Strains; Serotonin; Synaptic Transmission; Tritium; Zimeldine | 1982 |
Fluoxetine and two other serotonin uptake inhibitors without affinity for neuronal receptors.
Topics: Animals; Antidepressive Agents, Tricyclic; Brain; Brompheniramine; Cattle; Fluoxetine; Fluvoxamine; Male; Neurons; Oximes; Propylamines; Rats; Rats, Inbred Strains; Receptors, Histamine; Receptors, Neurotransmitter; Serotonin; Zimeldine | 1983 |
Electrophysiological investigations on the effect of repeated zimelidine administration on serotonergic neurotransmission in the rat.
Topics: 5,7-Dihydroxytryptamine; Animals; Brompheniramine; Electrophysiology; Hippocampus; Lysergic Acid Diethylamide; Male; Pyridines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Synaptic Transmission; Zimeldine | 1983 |
[Effect of chronic use of antidepressants on the state of benzodiazepine receptors in the mouse brain].
Topics: Administration, Oral; Animals; Antidepressive Agents; Binding Sites; Brain; Brompheniramine; Clomipramine; Flunitrazepam; Male; Mice; Receptors, Cell Surface; Receptors, GABA-A; Synaptic Membranes; Time Factors; Zimeldine | 1983 |
Pharmacokinetics of zimelidine. Systemic availability of zimelidine and norzimelidine in human volunteers.
Topics: Administration, Oral; Adult; Antidepressive Agents; Biological Availability; Brompheniramine; Dealkylation; Electrocardiography; Humans; Injections, Intravenous; Male; Pyridines; Time Factors; Zimeldine | 1980 |
Test-specific effects of the 5-HT reuptake inhibitors alaproclate and zimelidine on pain sensitivity and morphine analgesia.
Topics: Alanine; Analgesia; Animals; Behavior, Animal; Brompheniramine; Desipramine; Dose-Response Relationship, Drug; Male; Morphine; Naloxone; p-Chloroamphetamine; Pain; Pyridines; Rats; Serotonin; Zimeldine | 1980 |
Zimelidine-induced lipidosis in rats.
Topics: Adrenal Cortex; Animals; Antidepressive Agents; Brompheniramine; Lipidoses; Lung; Lymph Nodes; Male; Pigment Epithelium of Eye; Pyridines; Rats; Zimeldine | 1980 |
Anti-aggressive effect of zimelidine in isolated mice.
Topics: Aggression; Animals; Antidepressive Agents; Brompheniramine; Cerebral Cortex; Dose-Response Relationship, Drug; Humans; Male; Mice; Norepinephrine; p-Chloroamphetamine; Pyridines; Serotonin; Time Factors; Zimeldine | 1980 |
Zimelidine - a serotonin uptake blocker in the treatment of phobic anxiety.
Topics: Adult; Antidepressive Agents; Anxiety; Brompheniramine; Female; Humans; Male; Middle Aged; Phobic Disorders; Psychiatric Status Rating Scales; Pyridines; Serotonin Antagonists; Zimeldine | 1980 |
Para-halogenated phenethylamines: similar serotonergic effects in rats by different mechanisms.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Brain Chemistry; Brompheniramine; Dopamine; Fenclonine; Humans; Male; Norepinephrine; Phenethylamines; Rats; Serotonin; Zimeldine | 1980 |
Reduction of voluntary morphine consumption following treatment with zimelidine.
Topics: Animals; Brain Chemistry; Brompheniramine; Humans; Male; Morphine Dependence; Norepinephrine; Pyridines; Rats; Self Administration; Serotonin Antagonists; Zimeldine | 1980 |
Attenuation of pethidine-induced antinociception by zimelidine, an inhibitor of 5-hydroxytryptamine reuptake.
Topics: Animals; Brompheniramine; Drug Interactions; Male; Meperidine; Morphine; Pain; Pyridines; Rats; Reaction Time; Serotonin Antagonists; Zimeldine | 1980 |
Single dose pharmacokinetic data on zimelidine in depressed patients.
Topics: Antidepressive Agents; Brompheniramine; Depression; Female; Half-Life; Humans; Male; Pyridines; Zimeldine | 1980 |
Plasma levels of zimelidine and norzimelidine in endogenous depression.
Topics: Adult; Aged; Brompheniramine; Depression; Drug Evaluation; Female; Humans; Kinetics; Liver; Male; Middle Aged; Pyridines; Zimeldine | 1980 |
Biochemical effects of zimelidine in man.
Topics: Animals; Antidepressive Agents; Brain; Brompheniramine; Depression; Dopamine; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Norepinephrine; Pyridines; Rats; Serotonin; Zimeldine | 1980 |
Cardiovascular effects of amitriptyline, mianserin and zimelidine in depressed patients.
Topics: Adult; Amitriptyline; Antidepressive Agents; Blood Pressure; Brompheniramine; Cardiovascular Diseases; Depressive Disorder; Dibenzazepines; Female; Heart Rate; Humans; Male; Mianserin; Myocardial Contraction; Pyridines; Zimeldine | 1980 |
The pharmacology of zimelidine: a 5-HT selective reuptake inhibitor.
Topics: Animals; Behavior, Animal; Blood Platelets; Brain; Brompheniramine; Depression, Chemical; In Vitro Techniques; Male; Mice; Norepinephrine; Pyridines; Rats; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Synaptosomes; Zimeldine | 1981 |
Specific norepinephrine and serotonin uptake inhibitors in man: a crossover study with pharmacokinetic, biochemical, neuroendocrine and behavioral parameters.
Topics: Adolescent; Adult; Affective Disorders, Psychotic; Aged; Behavior; Brompheniramine; Desipramine; Double-Blind Method; Female; Hormones; Humans; Kinetics; Male; Middle Aged; Norepinephrine; Serotonin; Zimeldine | 1981 |
5-HT reuptake inhibitors plus tryptophan in endogenous depression.
Topics: Biogenic Amines; Brompheniramine; Clomipramine; Depressive Disorder; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Psychiatric Status Rating Scales; Serotonin Antagonists; Tryptophan; Zimeldine | 1981 |
The antidepressant efficacy of zimelidine and maprotiline.
Topics: Adult; Affective Disorders, Psychotic; Aged; Anthracenes; Antidepressive Agents; Brompheniramine; Depression; Double-Blind Method; Female; Humans; Male; Maprotiline; Middle Aged; Psychiatric Status Rating Scales; Pyridines; Time Factors; Zimeldine | 1981 |
Safety data on zimelidine hydrochloride following an overdose.
Topics: Adult; Antidepressive Agents; Brompheniramine; Electrocardiography; Female; Humans; Pyridines; Suicide, Attempted; Zimeldine | 1981 |
A pilot study of the effect of the 5-HT-uptake inhibitor, zimelidine, on phobic anxiety.
Topics: Adolescent; Adult; Anxiety; Body Weight; Brompheniramine; Electrocardiography; Humans; Middle Aged; Oxazepam; Phenelzine; Phobic Disorders; Psychiatric Status Rating Scales; Pyridines; Serotonin Antagonists; Zimeldine | 1981 |
The treatment of phobic anxiety by zimelidine.
Topics: Anxiety; Brompheniramine; Female; Humans; Male; Phobic Disorders; Psychiatric Status Rating Scales; Pyridines; Serotonin Antagonists; Zimeldine | 1981 |
Cardiovascular effects of zimelidine and other antidepressant in conscious rats.
Topics: Administration, Oral; Animals; Antidepressive Agents; Blood Pressure; Brompheniramine; Electrocardiography; Heart Rate; Hemodynamics; Injections, Intravenous; Male; Pyridines; Rats; Zimeldine | 1981 |
Zimelidine to geriatric patients: a pharmacokinetic and clinical study.
Topics: Aged; Antidepressive Agents; Brompheniramine; Depression; Female; Half-Life; Hemodynamics; Humans; Male; Psychiatric Status Rating Scales; Pyridines; Zimeldine | 1981 |
Cardiovascular, sedative and anticholinergic effects of amitriptyline and zimelidine in young and elderly volunteers.
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents; Brompheniramine; Depression; Hemodynamics; Humans; Hypnotics and Sedatives; Male; Motor Skills; Parasympatholytics; Pyridines; Salivation; Zimeldine | 1981 |
Pre- and postsynaptic effects of zimelidine and norzimelidine on the serotoninergic system: single cell studies in the rat.
Topics: Animals; Antidepressive Agents; Brompheniramine; Electrophysiology; gamma-Aminobutyric Acid; Male; Neurons; Norepinephrine; Pyridines; Rats; Serotonin; Synapses; Zimeldine | 1981 |
Metabolism of zimelidine in rat, dog and man. Identification and synthesis of the principal metabolites.
Topics: Adult; Animals; Antidepressive Agents; Biotransformation; Brompheniramine; Dogs; Humans; Male; Pyridines; Rats; Species Specificity; Zimeldine | 1981 |
Pharmacokinetics of zimelidine in humans--plasma levels and urinary excretion of zimelidine and norzimelidine after intravenous and oral administration of zimelidine.
Topics: Administration, Oral; Adult; Antidepressive Agents; Brompheniramine; Female; Humans; Injections, Intravenous; Kinetics; Male; Pyridines; Zimeldine | 1981 |
Chronic treatment with antidepressants: protentiation of clonidine-induced aggression in mice via noradrenergic mechanism.
Topics: Aggression; Amitriptyline; Animals; Antidepressive Agents; Brompheniramine; Clonidine; Drug Synergism; Fluoxetine; Humans; Male; Maprotiline; Mice; Zimeldine | 1981 |
Studies on the physical properties of tablets and tablet excipients. III. Water sorption and its effect on hardness and disintegration.
Topics: Brompheniramine; Caffeine; Humidity; Tablets; Technology, Pharmaceutical; Time Factors; Zimeldine | 1981 |
Studies on the role of central 5-HT neurons in avoidance learning: a behavioral and biochemical analysis.
Topics: Animals; Avoidance Learning; Brain; Brompheniramine; Cerebral Cortex; Desipramine; Fenclonine; Lysergic Acid Diethylamide; Male; Neurons; p-Chloroamphetamine; Rats; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Synaptosomes; Zimeldine | 1981 |
Binding of a specific 5-HT uptake inhibitor, [3H]norzimelidine, to rat brain homogenates.
Topics: Animals; Brain; Brompheniramine; In Vitro Techniques; Male; Pyridines; Rats; Rats, Inbred Strains; Serotonin Antagonists; Tritium; Zimeldine | 1982 |
Tertiary amines related to brompheniramine: preferred conformations for N-oxygenation by the hog liver flavin-containing monooxygenase.
Topics: Amines; Animals; Brompheniramine; Dealkylation; Flavins; In Vitro Techniques; Indicators and Reagents; Liver; Magnetic Resonance Spectroscopy; Microsomes, Liver; Mixed Function Oxygenases; Models, Molecular; Molecular Conformation; Spectrophotometry, Ultraviolet; Stereoisomerism; Swine; Zimeldine | 1993 |