bromouracil and arabinofuranosyluracil
bromouracil has been researched along with arabinofuranosyluracil in 11 studies
Research
Studies (11)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 7 (63.64) | 18.2507 |
2000's | 3 (27.27) | 29.6817 |
2010's | 1 (9.09) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Ashida, N; Baba, M; Ikeda, T; Machida, H; Sakata, S; Shigeta, S | 1 |
Schuster, AE; Whigan, DB | 1 |
Ikeda, K; Kawaguchi, K; Nagayama, S; Nakamura, Y; Nishiyama, T; Ogura, K; Ogura, Y; Okuda, H; Watabe, T; Yamaguchi, S | 1 |
Akimoto, S; Kataoka, K; Kinouchi, T; Matsuda, Y; Nakayama, H; Ohnishi, Y | 1 |
Diasio, RB; Haworth, S; Lee, PC; McCrary, MM; Olsen, SJ; Raymond, R; Tyring, SK; Yan, J | 1 |
Arakawa, K; Fukushima, M; Kato, A; Kawaguchi, Y; Nagayama, S; Nishiyama, T; Ogura, K; Okuda, H; Takubo, H; Watabe, T | 1 |
Kato, A; Ogura, K; Okuda, H; Takubo, H; Watabe, T | 1 |
Nishiyama, T; Ogura, K; Watabe, T | 1 |
Bergström, M; Fasth, KJ; Långström, B; Lu, L; Samuelsson, L; Sato, K | 1 |
Alauddin, MM; Conti, PS; Fissekis, JD; Park, R; Shahinian, A; Tohme, M | 1 |
Cai, H; Conti, PS; Li, Z | 1 |
Reviews
1 review(s) available for bromouracil and arabinofuranosyluracil
Article | Year |
---|---|
[Molecular toxicological mechanism of the lethal interactions of the new antiviral drug, sorivudine, with 5-fluorouracil prodrugs and genetic deficiency of dihydropyrimidine dehydrogenase].
Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Bromouracil; Dihydrouracil Dehydrogenase (NADP); Drug Interactions; Drug Therapy, Combination; Fluorouracil; Humans; NADP; Oxidoreductases; Prodrugs; Rats | 2002 |
Trials
2 trial(s) available for bromouracil and arabinofuranosyluracil
Article | Year |
---|---|
Manual and automated determination of 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil and its metabolite (E)-5-(2-bromovinyl)uracil in urine.
Topics: Antiviral Agents; Arabinofuranosyluracil; Autoanalysis; Bromouracil; Chromatography, High Pressure Liquid; Humans; Robotics | 1995 |
The effect of sorivudine on dihydropyrimidine dehydrogenase activity in patients with acute herpes zoster.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Analysis of Variance; Antiviral Agents; Arabinofuranosyluracil; Bromouracil; Chromatography, High Pressure Liquid; Dihydrouracil Dehydrogenase (NADP); Female; Herpes Zoster; Humans; Leukocytes, Mononuclear; Male; Middle Aged; Oxidoreductases; Software; Uracil | 1997 |
Other Studies
8 other study(ies) available for bromouracil and arabinofuranosyluracil
Article | Year |
---|---|
In vitro drug combination of 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil with anti-human immunodeficiency virus or anticancer nucleosides.
Topics: Antiviral Agents; Arabinofuranosyluracil; Bromouracil; Cytarabine; Drug Combinations; Floxuridine; Fluorouracil; Herpesvirus 3, Human; HIV-1; Humans; Zidovudine | 1992 |
Lethal drug interactions of sorivudine, a new antiviral drug, with oral 5-fluorouracil prodrugs.
Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Antiviral Agents; Arabinofuranosyluracil; Area Under Curve; Bone Marrow Diseases; Bromouracil; Dihydrouracil Dehydrogenase (NADP); Drug Synergism; Female; Intestine, Small; Liver; Oxidoreductases; Rats; Rats, Wistar; Tegafur; Tissue Distribution | 1997 |
Intestinal anaerobic bacteria hydrolyse sorivudine, producing the high blood concentration of 5-(E)-(2-bromovinyl)uracil that increases the level and toxicity of 5-fluorouracil.
Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Bacteria, Anaerobic; Bacteroides; Biotransformation; Bromouracil; Cecum; Fluorouracil; Gastric Mucosa; Gastrointestinal Contents; Intestinal Mucosa; Kidney; Liver; Male; Organ Specificity; Pentosyltransferases; Pyrimidine Phosphorylases; Rats; Rats, Sprague-Dawley | 1997 |
Suicidal inactivation of human dihydropyrimidine dehydrogenase by (E)-5-(2-bromovinyl)uracil derived from the antiviral, sorivudine.
Topics: Antiviral Agents; Arabinofuranosyluracil; Bromouracil; Dihydrouracil Dehydrogenase (NADP); Dose-Response Relationship, Drug; Humans; Oxidoreductases; Recombinant Proteins | 1998 |
A possible mechanism of eighteen patient deaths caused by interactions of sorivudine, a new antiviral drug, with oral 5-fluorouracil prodrugs.
Topics: Animals; Antimetabolites, Antineoplastic; Antiviral Agents; Arabinofuranosyluracil; Bromouracil; Cause of Death; Dihydrouracil Dehydrogenase (NADP); Drug Interactions; Fluorouracil; Half-Life; Herpes Zoster; Humans; Liver; Neoplasms; Oxidoreductases; Prodrugs; Rats; Tissue Distribution | 1998 |
Rat studies comparing 11C-FMAU, 18F-FLT, and 76Br-BFU as proliferation markers.
Topics: Animals; Arabinofuranosyluracil; Bromine Radioisotopes; Bromouracil; Cell Division; Dideoxynucleosides; DNA; Fluorine Radioisotopes; Male; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Tomography, Emission-Computed | 2002 |
Synthesis of 2'-deoxy-2'-[18F]fluoro-5-bromo-1-beta-D-arabinofuranosyluracil ([18F]-FBAU) and 2'-deoxy-2'-[18F]fluoro-5-chloro-1-beta-D-arabinofuranosyl-uracil ([18F]-FCAU), and their biological evaluation as markers for gene expression.
Topics: Animals; Arabinofuranosyluracil; Biomarkers, Tumor; Bromouracil; Colonic Neoplasms; Fluorouracil; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genetic Markers; Humans; Isotope Labeling; Metabolic Clearance Rate; Mice; Mice, Nude; Organ Specificity; Radioisotope Dilution Technique; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Thymidine Kinase; Tissue Distribution; Tomography, Emission-Computed; Viral Proteins | 2004 |
The improved syntheses of 5-substituted 2'-[18F]fluoro-2'-deoxy-arabinofuranosyluracil derivatives ([18F]FAU, [18F]FEAU, [18F]FFAU, [18F]FCAU, [18F]FBAU and [18F]FIAU) using a multistep one-pot strategy.
Topics: Arabinofuranosyluracil; Bromouracil; Fluorouracil; Radiochemistry; Reference Standards | 2011 |