bromodeoxyuridine has been researched along with methotrexate in 70 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 48 (68.57) | 18.7374 |
| 1990's | 9 (12.86) | 18.2507 |
| 2000's | 9 (12.86) | 29.6817 |
| 2010's | 2 (2.86) | 24.3611 |
| 2020's | 2 (2.86) | 2.80 |
| Authors | Studies |
|---|---|
| Hansch, C; Khwaja, TA; Selassie, CD | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Bogenhagen, D; Clayton, DA | 1 |
| Geissler, E; Scherneck, S; Theile, M | 1 |
| Nakamura, N; Okada, S | 1 |
| Faggin, P; Parodi, S; Raffetto, G; Zunino, A | 1 |
| Goldstein, MN; Kolber, AR; Moore, BW; Perumal, AS | 1 |
| Wakisaka, S | 1 |
| Siminovitch, L | 1 |
| Santi, DV; Wataya, Y | 1 |
| Andersen, HA; Rasmussen, L; Zeuthen, E | 1 |
| Johnson, B; Westergaard, O | 1 |
| Mueller, GC; Planck, SR | 1 |
| Bagshaw, MA; Donaldson, SS; Goffinet, DR; Kaplan, HS; Wilbur, JR | 1 |
| Chaabouni, H; Hila, L | 1 |
| Cornelisse, CJ; Keijzer, R; van de Velde, CJ; van Dierendonck, JH; Wijsman, JH | 1 |
| Benson, N; Bruce-Gregorios, JH; Chen, MG; Soucy, D | 1 |
| Fujimoto, T; Katano, N; Niwa, M; Tsurusawa, M | 2 |
| Hamlin, JL; Leu, TH; Ma, C | 1 |
| Jean, P; Lemieux, N; Richer, CL | 1 |
| Hoy, CA; Kovacs, M; Rice, GC; Schimke, RT | 1 |
| Benedict, WF; Heidelberger, C; Peterson, AR | 1 |
| Prasad, R; Savage, JR | 1 |
| Ayusawa, D; Kaneda, S; Koyama, H; Seno, T; Shimizu, K; Takeishi, K | 1 |
| Bodycote, J; Fero, ML; Hahn, PJ; Kapp, LN; Morgan, WF; Painter, RB; Pantelias, GE | 1 |
| Di Berardino, D; di Meo, GP; Ferrara, L; Gustavsson, I; Iannuzzi, L; Lioi, MB | 1 |
| Andersen, HA | 1 |
| Houlihan, RB; Roby, R; Teskey, C | 1 |
| Hooper, DC | 1 |
| Cassidy, EP; Fischer, DS; Welch, AD | 1 |
| Hoshino, T; Nagai, M; Sano, K | 1 |
| Hoshino, T; Wilson, CB | 1 |
| Landolt, AM | 1 |
| Bowman, RL; Braslow, NM | 1 |
| Koyama, Y; Matsutani, M; Sing, OK; Takakura, K | 1 |
| Mundinger, F | 1 |
| Balazs, I; Brown, EH; Schildkraut, CL | 1 |
| Calabresi, P; Fischer, GA; Lee, SY | 1 |
| Goldstein, MN; Silbert, SW | 1 |
| Muzik, H; Paterson, AR; Warnick, CT | 1 |
| Rizki, RM; Rizki, TM | 1 |
| Jasińska, JK; Steffen, JA; Swierkowska, KM | 1 |
| Bernheim, NJ; Clive, D; Flamm, WG; Machesko, MR | 1 |
| Fischer, HU; Jobski, C; Mundinger, F; Ostertag, C; Vogt, P | 1 |
| Hsu, TC; Humphrey, RM | 1 |
| Bagshaw, MA; Doggett, RL; Kaplan, HS; Nelsen, TS; Smith, KC | 1 |
| Kałuzewski, B | 1 |
| Burry, RW | 1 |
| Nielsen, KB; Tommerup, N | 1 |
| Andersen, HA; Keiding, J | 1 |
| Fujimoto, S; Ogawa, M; Sakurai, Y | 1 |
| Dove, WF; Laffler, TG | 1 |
| Bijlsma, JW; Damen, CA; Duursma, SA; Lafeber, FP; Scheven, BA; van der Veen, MJ; Van Rijn, HJ | 1 |
| Pancheva, SN | 1 |
| Di Meo, GP; Iannuzzi, L | 1 |
| Drouin, R; Lavoie, J | 1 |
| Cabanillas, F; Cox, JD; Dabaja, BS; Ha, CS; Kyritsis, AP; Levin, V; McLaughlin, P; Meyers, CA; Preti, HA; Pro, B; Seabrooke, LF; Wilder, RB; Yung, WK | 1 |
| KAJIWARA, K; MUELLER, GC | 1 |
| Ernst, H; Fahrig, R; Fiedler, B; Heinrich, JC; Krupitza, G; Leisser, C; Nickel, B; Praha, C; Scherthan, H; Sonntag, D; Wilfert, F | 1 |
| Lehnert, S; Li, Y; Owusu, A | 1 |
| M'Rabet, L; van Beek, NM; van den Berg, JJ; van't Land, B | 1 |
| Cool, JC; Fan, C; Foster, BK; Scherer, MA; Xian, CJ | 1 |
| Inoue, K; Inoue, Y; Kanbe, K; Suzuki, Y | 1 |
| Arora, J; Blair, IA; Hammons, AL; Jochems, J; Summers, CM; Whitehead, AS; Zhang, S | 1 |
| Corde, S; Konstantinov, K; Lerch, ML; Oktaria, S; Rosenfeld, AB; Tehei, M | 1 |
| Anosri, T; Aranarochana, A; Kaewngam, S; Pannangrong, W; Sirichoat, A; Welbat, JU; Wigmore, P | 1 |
| Arrow, SS; Felis, SC; Hillenmayer, A; Koenig, SF; Strehle, LD; Vounotrypidis, E; Wertheimer, CM; Wolf, A | 1 |
4 review(s) available for bromodeoxyuridine and methotrexate
| Article | Year |
|---|---|
Radiation sensitizers.
Topics: Animals; Antineoplastic Agents; Bromodeoxycytidine; Bromodeoxyuridine; Carcinoma; Deoxyuridine; Dogs; Dose-Response Relationship, Radiation; Floxuridine; Humans; Hypoxia; Idoxuridine; Lung Neoplasms; Methotrexate; Metronidazole; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents; Research; Sarcoma, Experimental; Skin | 1976 |
On the nature of hereditable variation in cultured somatic cells.
Topics: Amanitins; Azaguanine; Bromodeoxyuridine; Cell Line; Cells, Cultured; Chromosomes; Colchicine; Cycloheximide; Diploidy; Drug Resistance; Genes; Genes, Lethal; Genes, Recessive; Genetic Variation; Hybrid Cells; Hydroxyurea; Immunoglobulins; Lectins; Methotrexate; Mutation; Ouabain; Phenotype; Polyploidy; Temperature | 1976 |
Cell division and DNA replication in synchronous Tetrahymena cultures.
Topics: Animals; Bromodeoxyuridine; Carbon Dioxide; Cell Division; Colchicine; Cytological Techniques; DNA Replication; Hot Temperature; Hydrostatic Pressure; Light; Methotrexate; RNA; Schizosaccharomyces; Starvation; Tetrahymena; Tetrahymena pyriformis; Time Factors; Vinblastine | 1975 |
Oncogenic transformation of C3H/10T1/2 Cl 8 mouse embryo fibroblasts by inhibitors of nucleotide metabolism.
Topics: Animals; Bromodeoxyuridine; Cell Line; Cell Transformation, Neoplastic; Cytidine; Deoxycytidine; Deoxyribonucleotides; DNA; Embryo, Mammalian; Fibroblasts; Floxuridine; Fluorouracil; Idoxuridine; Methotrexate; Mice; Mice, Inbred C3H; Mutation; Thymidine; Trifluridine | 1985 |
2 trial(s) available for bromodeoxyuridine and methotrexate
| Article | Year |
|---|---|
Primary central nervous system lymphoma: Phase I evaluation of infusional bromodeoxyuridine with whole brain accelerated fractionation radiation therapy after chemotherapy.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Brain Diseases; Bromodeoxyuridine; Central Nervous System Neoplasms; Cisplatin; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Dexamethasone; Dose-Response Relationship, Drug; Female; Humans; Idarubicin; Infusions, Intravenous; Lymphoma; Male; Methotrexate; Middle Aged; Treatment Outcome | 2003 |
Histological analysis of synovium in cases of effect attenuation associated with infliximab therapy in rheumatoid arthritis.
Topics: Aged; Antibodies, Monoclonal; Antigens, CD20; Antirheumatic Agents; Arthritis, Rheumatoid; Bromodeoxyuridine; Female; Humans; Immunohistochemistry; Infliximab; Interleukin-6; Male; Matrix Metalloproteinase 3; Methotrexate; Middle Aged; NF-kappa B; Synovial Membrane; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2008 |
64 other study(ies) available for bromodeoxyuridine and methotrexate
| Article | Year |
|---|---|
Structure-activity relationships of antineoplastic agents in multidrug resistance.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cricetinae; Dactinomycin; Drug Resistance; Leukemia L1210; Mice; Regression Analysis; Structure-Activity Relationship; Tumor Cells, Cultured | 1990 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Thymidylate nucleotide supply for mitochondrial DNA synthesis in mouse L-cells. Effect of 5-fluorodeoxyuridine and methotrexate in thymidine kinase plus and thymidine kinase minus cells.
Topics: Animals; Bromodeoxyuridine; Cell Nucleus; DNA, Mitochondrial; Floxuridine; L Cells; Methotrexate; Mice; Phosphates; Thymidine; Thymidine Kinase | 1976 |
Mutagenesis by simian virus 40. I. detection of mutations in Chinese hamster cell lines using different resistance markers.
Topics: Azaguanine; Bromodeoxyuridine; Cell Line; Cell Survival; Colchicine; Drug Resistance; Methotrexate; Mutation; Simian virus 40 | 1976 |
Cell-cycle dependency of BUdR-induced mutation for six genetic markers in cultured mammalian cells.
Topics: Animals; Asparagine; Bromodeoxyuridine; Cell Cycle; Cytarabine; DNA; Drug Resistance; Genes; L Cells; Methotrexate; Mice; Mutation; Ouabain; Thioguanine; Thymidine | 1979 |
[Induction of sister chromatid exchange (SCE) and incorporation of BUdR in mouse cells treated with methotrexate].
Topics: Animals; Bromodeoxyuridine; Cells, Cultured; Crossing Over, Genetic; Methotrexate; Mice; Sister Chromatid Exchange | 1979 |
Drug-induced differentiation of a rat glioma in vitro: II. the expression of S-100, a glial specific protein and steroid sulfatase.
Topics: Animals; Bromodeoxyuridine; Cell Division; Cells, Cultured; DNA Replication; Glioma; In Vitro Techniques; Methotrexate; Neoplasm Proteins; Rats; Steroids; Sulfatases; Time Factors | 1978 |
In vitro correlation of drug concentrations and radiosensitization in combination therapy with 5-bromo-2'-deoxyuridine, methotrexate, and radiation.
Topics: Bromodeoxyuridine; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; L Cells; Methotrexate; Radiation-Sensitizing Agents | 1979 |
Thymidylate synthetase catalyzed dehalogenation of 5-bromo-and 5-iodo-2'-deoxyuridylate.
Topics: Bromodeoxyuridine; Drug Resistance, Microbial; Idoxuridine; Lacticaseibacillus casei; Methotrexate; Methyltransferases; Spectrophotometry, Ultraviolet; Thymidylate Synthase; Uracil Nucleotides | 1975 |
Accumulation of replicative DNA intermediates in Tetrahymena after excision-repairable damage to DNA.
Topics: Animals; Bromodeoxyuridine; Centrifugation, Density Gradient; DNA Repair; Methotrexate; Molecular Weight; Tetrahymena pyriformis; Thymine; Uridine | 1976 |
Deoxyribonucleic acid chain growth and organization of replicating units in HeLa cells.
Topics: Bromodeoxyuridine; Cycloheximide; DNA Replication; DNA, Neoplasm; Genes; HeLa Cells; Methotrexate; Molecular Weight; Temperature; Thymidine | 1977 |
Combined radiosensitizer infusion and irradiation of osteogenic sarcomas.
Topics: Bromodeoxyuridine; Child; Female; Humans; Infusions, Parenteral; Leucovorin; Male; Methotrexate; Osteosarcoma; Radiation Dosage; Radiation-Sensitizing Agents | 1975 |
[High resolution cytogenetic techniques or microcytogenetics].
Topics: Bromodeoxyuridine; Cell Division; Humans; Karyotyping; Methotrexate; Thymidine | 1992 |
Cell-cycle-related staining patterns of anti-proliferating cell nuclear antigen monoclonal antibodies. Comparison with BrdUrd labeling and Ki-67 staining.
Topics: Antibodies, Monoclonal; Breast Neoplasms; Bromodeoxyuridine; Cell Cycle; Cell Division; Female; Flow Cytometry; G1 Phase; Humans; Immunohistochemistry; Methotrexate; Nuclear Proteins; Ovarian Neoplasms; Proliferating Cell Nuclear Antigen; Resting Phase, Cell Cycle; S Phase; Tamoxifen | 1991 |
Effect of methotrexate on cell cycle and DNA synthesis of astrocytes in primary culture: flow cytometric studies.
Topics: Animals; Astrocytes; Bromodeoxyuridine; Cell Cycle; Cells, Cultured; DNA; Flow Cytometry; Methotrexate; Propidium | 1991 |
Methotrexate cytotoxicity as related to irreversible S phase arrest in mouse L1210 leukemia cells.
Topics: Animals; Bromodeoxyuridine; DNA; Flow Cytometry; Interphase; Leukemia L1210; Methotrexate; Mice; Tumor Cells, Cultured | 1990 |
Multiple origins of replication in the dihydrofolate reductase amplicons of a methotrexate-resistant chinese hamster cell line.
Topics: Animals; Bromodeoxyuridine; Cell Line; Cosmids; Cricetinae; Cricetulus; DNA; DNA Replication; Drug Resistance; Female; Gene Amplification; Methotrexate; Ovary; Tetrahydrofolate Dehydrogenase | 1990 |
Combined myeloid cell synchronization and chromosome G-banding by bromodeoxyuridine.
Topics: Bone Marrow; Bone Marrow Cells; Bromodeoxyuridine; Cell Division; Chromosome Banding; Humans; Karyotyping; Methotrexate; Staining and Labeling | 1987 |
Over-replication of DNA in S phase Chinese hamster ovary cells after DNA synthesis inhibition.
Topics: Animals; Aphidicolin; Base Sequence; Bromodeoxyuridine; Cell Line; Cell Survival; Cricetinae; Cricetulus; Diterpenes; DNA; DNA Replication; Drug Resistance; Female; Flow Cytometry; Gene Amplification; Hydroxyurea; Interphase; Methotrexate; Ovary; Ultraviolet Rays | 1987 |
Flow cytometric analysis by bromodeoxyuridine/DNA assay of cell cycle perturbation of methotrexate-treated mouse L1210 leukemia cells.
Topics: Animals; Bromodeoxyuridine; Cell Cycle; DNA Replication; Dose-Response Relationship, Drug; Flow Cytometry; Leukemia L1210; Methotrexate; Time Factors | 1988 |
Generalized blocking in S phase by methotrexate.
Topics: Animals; Bromodeoxyuridine; Cell Survival; Cells, Cultured; Cricetinae; Fibroblasts; Interphase; Mesocricetus; Methotrexate; Mitotic Index | 1988 |
Induction, by thymidylate stress, of genetic recombination as evidenced by deletion of a transferred genetic marker in mouse FM3A cells.
Topics: Animals; Bromodeoxyuridine; Cell Line; Cell Survival; Chromosome Deletion; Clone Cells; Genes; Kinetics; Mammary Neoplasms, Experimental; Methotrexate; Mice; Recombination, Genetic; Thymidine Monophosphate; Thymidylate Synthase; Thymine Nucleotides | 1986 |
A cytogenetic investigation of DNA rereplication after hydroxyurea treatment: implications for gene amplification.
Topics: Animals; Bromodeoxyuridine; Cell Line; Cricetinae; Cricetulus; DNA Replication; Drug Resistance; Female; Gene Amplification; Hydroxyurea; Karyotyping; Metaphase; Methotrexate; Ovary | 1986 |
Fluorescent G- and C-bands in mammalian chromosomes by using early BrdU incorporation simultaneous to methotrexate treatment.
Topics: Animals; Bromodeoxyuridine; Cattle; Cells, Cultured; Chromosome Banding; Chromosomes; Chromosomes, Human; Humans; Methotrexate | 1985 |
Replication of macronuclear DNA in the cytoplasm of Tetrahymena pyriformis.
Topics: Autoradiography; Bromodeoxyuridine; Cell Division; Cell Nucleus; Centrifugation, Density Gradient; Cytoplasm; DNA; DNA Replication; Hybridization, Genetic; Methotrexate; Tetrahymena pyriformis; Tritium; Uridine | 1974 |
Inhibition of plaque formation by myxoma and fibroma viruses with pyrimidine analogues.
Topics: Antiviral Agents; Benzimidazoles; Bromodeoxyuridine; Culture Techniques; Cytosine; DNA, Viral; Fibroma; Floxuridine; Fluorouracil; Idoxuridine; Mercaptopurine; Methotrexate; Myxoma virus; Nucleosides; Oncogenic Viruses; Thiosemicarbazones; Thymine | 1965 |
[The effect of antileukemia agents on hematopoietic cell lines in intraracial embryonic graft of the spleen in C-57Bl-6 mice].
Topics: Animals; Bromodeoxyuridine; Cyclophosphamide; Hematopoietic System; Mercaptopurine; Methotrexate; Mice; Spleen | 1966 |
Immunosuppression by pyrimidine nucleoside analogs.
Topics: Animals; Antibody Formation; Antimetabolites; Azathioprine; Bromodeoxyuridine; Chloramphenicol; Cytarabine; Cytosine Nucleotides; Erythrocytes; Floxuridine; Hemagglutination Tests; Idoxuridine; Injections, Intraperitoneal; Injections, Subcutaneous; Mercaptoethanol; Mercaptopurine; Methotrexate; Mice; Nucleosides; Sheep | 1966 |
Radiosensitization of brain tumor cells with a thymidine analogue (bromouridine).
Topics: Astrocytoma; Brain Neoplasms; Bromodeoxyuridine; Culture Techniques; DNA; Floxuridine; Fluorouracil; Follow-Up Studies; Glioma; Humans; Meningioma; Methotrexate; Oligodendroglioma; Radiation-Sensitizing Agents; Thymidine | 1968 |
Current trends in the chemotherapy of brain tumors with special reference to glioblastomas.
Topics: Alkaloids; Antibiotics, Antineoplastic; Antineoplastic Agents; Azaguanine; Blood Vessel Prosthesis; Blood-Brain Barrier; Brain; Brain Neoplasms; Bromodeoxyuridine; Cell Division; Cell Transformation, Neoplastic; Disease Models, Animal; Fluorouracil; Glioblastoma; Humans; Injections, Intra-Arterial; Injections, Spinal; Mechlorethamine; Methotrexate; Nitroso Compounds; Thiotepa; Time Factors; Urea; Vincristine | 1969 |
[Results of postoperative treatment of glioblastoma multiforme with a radiation-sensitizing substance (5-bromo-2-deoxyuridine)].
Topics: Adult; Aged; Alopecia; Brain Edema; Brain Neoplasms; Bromodeoxyuridine; Drug Interactions; Exanthema; Glioblastoma; Glossitis; Humans; Leukopenia; Methotrexate; Middle Aged; Postoperative Care; Prognosis; Radiation-Sensitizing Agents; Stomatitis; Thrombocytopenia | 1971 |
Capillary tube scanning applied to cell growth kinetics.
Topics: Animals; Bromodeoxyuridine; Carcinoma, Hepatocellular; Cell Biology; Cell Count; Cells; Cells, Cultured; Hypoxanthines; Kinetics; Liver Neoplasms; Lymphoma; Methotrexate; Mice; Mitosis; Neoplasms, Experimental; Photometry; Rats; Thymidine | 1972 |
[Treatment of malignant brain tumors by the intrathecal administration of BAR (EUdR-antimetabolite-radiation)].
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Antimetabolites; Brain Neoplasms; Bromodeoxyuridine; Carcinoma, Squamous Cell; Child; Child, Preschool; Ependymoma; Female; Glioblastoma; Humans; Injections, Spinal; Male; Medulloblastoma; Meningioma; Methotrexate; Middle Aged; Mitomycins; Pinealoma; Radiation-Sensitizing Agents; Radiotherapy, High-Energy; Retinoblastoma | 1972 |
[Clinical and experimental results of interstitial Curie-therapy combined with radiosensitizing agents in DS carcinoma of the rat and in infiltrating brain neoplasms].
Topics: Animals; Brain Neoplasms; Bromodeoxyuridine; Carcinosarcoma; Cytidine; Ependymoma; Glioblastoma; Humans; Iridium; Methotrexate; Oligodendroglioma; Radiation-Sensitizing Agents; Rats; Thymidine | 1972 |
The temporal order of replication of some DNA cistrons.
Topics: Animals; Anura; Autoradiography; Bromodeoxyuridine; Cell Division; Cell Line; Cell Nucleus; DNA; DNA Replication; DNA, Viral; Genes; Kidney; Methotrexate; Mice; Operon; Polyomavirus; Ribosomes; Simian virus 40; Thymidine; Time Factors; Tritium | 1974 |
Detection of chemical mutagens using a host-mediated assay (L5178Y) mutagenesis system.
Topics: Animals; Biological Assay; Bromodeoxyuridine; Cell Line; Cells, Cultured; Clone Cells; Cytarabine; Dose-Response Relationship, Drug; Drug Resistance; Leukemia, Lymphoid; Mesylates; Methotrexate; Mice; Mutagens; Mutation; Thymidine | 1974 |
Drug-induced differentiation of a rat glioma in vitro.
Topics: Animals; Bromodeoxyuridine; Cell Differentiation; Cell Line; Clone Cells; Dactinomycin; Desmosomes; Glioma; Glycogen; In Vitro Techniques; Methotrexate; Microscopy, Electron; Microscopy, Phase-Contrast; Rats; Stimulation, Chemical | 1972 |
Interference with nucleoside transport in mouse lymphoma cells proliferating in culture.
Topics: Adenosine; Animals; Ascitic Fluid; Aza Compounds; Biological Transport; Bromodeoxyuridine; Carbon Isotopes; Cell Division; Cell-Free System; Cells, Cultured; Guanosine; Inosine; Lymphoma; Male; Mercaptopurine; Methotrexate; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Pyrazoles; Pyrimidinones; Pyrroles; Ribonucleosides; Thymidine; Time Factors; Transplantation, Homologous | 1972 |
The role of thymidylate synthetase inhibitors in bromodeoxyuridine-induced neoplasia in Drosophila.
Topics: Animals; Bromodeoxyuridine; Centrifugation, Density Gradient; DNA; Drosophila; Fluorine; Fluorouracil; Idoxuridine; Larva; Methotrexate; Methyltransferases; Neoplasms, Experimental; Thymidine; Thymidylate Synthase; Tritium | 1973 |
5-Ethyl-2'-deoxyuridine: evidence for incorporation into DNA and evaluation of biological properties in lymphocyte cultures grown under conditions of amethopterine-imposed thymidine deficiency.
Topics: Autoradiography; Bromodeoxyuridine; Carbon Radioisotopes; Cells, Cultured; Chromosome Aberrations; Culture Media; Deoxyuridine; DNA; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Lymphocytes; Methotrexate; Mitosis; Thymidine; Time Factors | 1973 |
A mutational assay system using the thymidine kinase locus in mouse lymphoma cells.
Topics: Animals; Bromodeoxyuridine; Cell Count; Cell Line; Clone Cells; Culture Media; Drug Resistance; Ethylamines; Glycine; Hypoxanthines; Lymphoma; Methane; Methanol; Methotrexate; Mice; Mutation; Neoplasms, Experimental; Phenotype; Radiation Genetics; Sulfonic Acids; Thymidine; Thymidine Kinase; Xanthenes | 1972 |
[Clinical and experimental results of interstitial Brachy-Curie-therapy combined with radiation sensitizing agents in infiltrative growing brain neoplasms].
Topics: Animals; Brain Neoplasms; Bromodeoxyuridine; Carcinosarcoma; Cytidine; Fluorouracil; Guanosine; Iridium; Methotrexate; Neoplasms, Experimental; Radiation-Sensitizing Agents; Rats; Thymine | 1972 |
Further studies on biological properties of mammalian cell lines resistant to 5-bromodeoxyuridine.
Topics: Animals; Bromodeoxyuridine; Chromosomes; Cricetinae; DNA; Fibroblasts; Idoxuridine; Methotrexate; Mice; Thymidine; Thymidine Kinase; Tritium | 1965 |
Intra-arterial 5-bromodeoxyuridine and x-ray therapy.
Topics: Bromodeoxyuridine; Carbon Isotopes; Carcinoma, Squamous Cell; Carotid Arteries; DNA, Neoplasm; Facial Neoplasms; Female; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Injections, Intra-Arterial; Male; Methotrexate; Mouth Neoplasms; Radiation-Sensitizing Agents; Uterine Cervical Neoplasms | 1967 |
BrdU-Hoechst-Giemsa analysis of DNA replication in synchronized lymphocyte cultures. Study of human X and Y chromosomes.
Topics: Bromodeoxyuridine; Cell Cycle; Cells, Cultured; Chromosome Aberrations; Chromosome Banding; DNA Replication; Female; Humans; Kinetics; Lymphocyte Activation; Lymphocytes; Male; Methotrexate; Mitotic Index; Sex Chromosomes; Sister Chromatid Exchange; Staining and Labeling; X Chromosome; Y Chromosome | 1982 |
Antimitotic drugs that enhance neuronal survival in olfactory bulb cell cultures.
Topics: Animals; Bromodeoxyuridine; Cells, Cultured; Cytarabine; Depression, Chemical; Floxuridine; Hydroxyurea; Methotrexate; Mitosis; Olfactory Bulb; Potassium; Rats; Rats, Inbred Strains; Thymidine | 1983 |
Cytogenetic investigations in mentally retarded and normal males from 14 families with the fragile site at Xq28. Results of folic acid treatment on fra(X) expression.
Topics: Adolescent; Adult; Bromodeoxyuridine; Cells, Cultured; Child; Child, Preschool; Chromosome Fragile Sites; Chromosome Fragility; Female; Fibroblasts; Floxuridine; Folic Acid; Gene Expression Regulation; Genetic Markers; Humans; Infant; Intellectual Disability; Lymphocytes; Male; Methotrexate; Middle Aged; X Chromosome | 1984 |
Induction of DNA polymerase in Tetrahymena pyriformis.
Topics: Bromodeoxyuridine; DNA-Directed DNA Polymerase; Enzyme Induction; Methotrexate; Tetrahymena pyriformis; Ultraviolet Rays; Uridine | 1981 |
Hypothetical mechanism of therapeutic synergism induced by the combination of 6-thioguanine and 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-1-(2-chloroethyl)-1-nitrosourea hydrochloride.
Topics: Animals; Antineoplastic Agents; Bromodeoxyuridine; Drug Evaluation, Preclinical; Drug Therapy, Combination; Female; Fluorouracil; Leukemia L1210; Methotrexate; Mice; Mice, Inbred Strains; Nimustine; Nitrosourea Compounds; Thioguanine | 1982 |
Thymidine-dependent growth of Physarum polycephalum amoebae treated with methotrexate in axenic culture.
Topics: Bromodeoxyuridine; Culture Media; Methotrexate; Physarum; Thymidine | 1981 |
Effects of methotrexate on human osteoblasts in vitro: modulation by 1,25-dihydroxyvitamin D3.
Topics: Alkaline Phosphatase; Analysis of Variance; Antirheumatic Agents; Arthritis, Rheumatoid; Bone and Bones; Bone Remodeling; Bromodeoxyuridine; Calcitriol; Cell Differentiation; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Femur Head; Humans; Immunohistochemistry; Methotrexate; Osteoblasts; Osteocalcin; Radioimmunoassay | 1995 |
Methotrexate potentiates anti-herpes simplex virus type 1 activity of E-5-(2-bromovinyl)-2'-deoxyuridine.
Topics: Antiviral Agents; Bromodeoxyuridine; Cell Line; Drug Synergism; Herpesvirus 1, Human; Humans; Methotrexate | 1995 |
MTX-block during S-phase in BrdU-treated cells depends on species and medium used.
Topics: Animals; Blood Cells; Bromodeoxyuridine; Buffaloes; Buffers; Cattle; Chromosome Banding; Humans; Methotrexate; S Phase; Sheep; Species Specificity | 1996 |
Lymphoblasts already in the DNA synthesis phase of the cell cycle can be reversibly arrested at the R/G transition.
Topics: Bromodeoxyuridine; Cell Cycle; Cell Line, Transformed; Chromosome Banding; Chromosomes, Human; DNA; DNA Replication; Flow Cytometry; Fluorouracil; Humans; Karyotyping; Kinetics; Lymphocyte Activation; Lymphocytes; Methotrexate; Mimosine; S Phase; Thymidine | 2001 |
MOLECULAR EVENTS IN THE REPRODUCTION OF ANIMAL CELLS. 3. FRACTIONAL SYNTHESIS OF DEOXYRIBONUCLEIC ACID WITH 5-BROMODEOXYURIDINE AND ITS EFFECT ON CLONING EFFICIENCY.
Topics: Bromodeoxyuridine; Cloning, Organism; DNA; Metabolism; Methotrexate; Nucleosides; Pharmacology; Research; Tissue Culture Techniques | 1964 |
Inhibition of induced chemoresistance by cotreatment with (E)-5-(2-bromovinyl)-2'-deoxyuridine (RP101).
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bromodeoxyuridine; Cisplatin; DNA-Binding Proteins; Doxorubicin; Drug Resistance, Neoplasm; Drug Synergism; Electrophoresis, Gel, Two-Dimensional; Fibroblasts; Ifosfamide; Methotrexate; Mice; Mitomycin; Mitoxantrone; NAD(P)H Dehydrogenase (Quinone); Rats; Rats, Sprague-Dawley; Sarcoma, Yoshida; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; STAT3 Transcription Factor; Trans-Activators; Tumor Cells, Cultured; Vinblastine; Vinorelbine | 2003 |
Treatment of intracranial rat glioma model with implant of radiosensitizer and biomodulator drug combined with external beam radiotherapy.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Brain Neoplasms; Bromodeoxyuridine; Cell Line, Tumor; Combined Modality Therapy; Drug Combinations; Drug Implants; Fluorouracil; Glioma; Immunologic Factors; Methotrexate; Phosphonoacetic Acid; Radiation-Sensitizing Agents; Rats | 2004 |
Lactoferrin reduces methotrexate-induced small intestinal damage, possibly through inhibition of GLP-2-mediated epithelial cell proliferation.
Topics: Animals; Antimetabolites, Antineoplastic; Bromodeoxyuridine; Caco-2 Cells; Cell Division; Cells, Cultured; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Epithelial Cells; Female; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Humans; Intestinal Mucosa; Lactoferrin; Methotrexate; Peptides; Polymerase Chain Reaction; Rats; Rats, Inbred Strains | 2004 |
Folinic acid attenuates methotrexate chemotherapy-induced damages on bone growth mechanisms and pools of bone marrow stromal cells.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Bone and Bones; Bone Development; Bone Marrow Cells; Bromodeoxyuridine; Cell Proliferation; Chondrocytes; Collagen Type II; Gene Expression Regulation; Growth Plate; Leucovorin; Male; Methotrexate; Organ Size; Osteoblasts; Pericytes; Rats; Rats, Sprague-Dawley; Stromal Cells | 2008 |
Methotrexate modulates folate phenotype and inflammatory profile in EA.hy 926 cells.
Topics: Antimetabolites, Antineoplastic; Atherosclerosis; Bromodeoxyuridine; Cell Line; Cell Proliferation; Cell Survival; Folic Acid; Folic Acid Antagonists; Folic Acid Deficiency; Gene Expression; Humans; Inflammation; Methotrexate; Phenotype | 2014 |
Indirect radio-chemo-beta therapy: a targeted approach to increase biological efficiency of x-rays based on energy.
Topics: Animals; Antimetabolites, Antineoplastic; Bromodeoxyuridine; Cell Cycle; Cell Line, Tumor; Combined Modality Therapy; DNA Repair; Flow Cytometry; Glioma; Methotrexate; Photons; Radiation-Sensitizing Agents; Rats; X-Rays | 2015 |
Neuroprotective properties of chrysin on decreases of cell proliferation, immature neurons and neuronal cell survival in the hippocampal dentate gyrus associated with cognition induced by methotrexate.
Topics: Animals; Bromodeoxyuridine; Cell Proliferation; Cell Survival; Cognition; Dentate Gyrus; Doublecortin Domain Proteins; Flavonoids; Hippocampus; Ki-67 Antigen; Male; Memory Disorders; Methotrexate; Neurogenesis; Neurons; Rats; Rats, Sprague-Dawley; Tetrahydrofolate Dehydrogenase | 2022 |
Inhibition of proliferative vitreoretinopathy by a newly developed methotrexate loaded drug carrier in vitro.
Topics: Bromodeoxyuridine; Epiretinal Membrane; Humans; Methotrexate; Retinal Detachment; Vitrectomy; Vitreoretinopathy, Proliferative | 2023 |