bromodeoxyuridine has been researched along with fluorouracil in 125 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 62 (49.60) | 18.7374 |
| 1990's | 24 (19.20) | 18.2507 |
| 2000's | 26 (20.80) | 29.6817 |
| 2010's | 13 (10.40) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, MS; Prusoff, WH; Schinazi, RF | 1 |
| Hansch, C; Khwaja, TA; Selassie, CD | 1 |
| Cordeiro, MN; Fernández, F; García-Mera, X; Helguera, AM; Rodríguez-Borges, JE | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Baker, MS; Benedict, WF; Heidelberger, C; Jones, PA; Mondal, S; Rapp, U | 1 |
| Cass, CE; Lynch, TP; Paterson, AR | 1 |
| Kaplan, HS | 1 |
| Michalová, K; Musilová, J; Urban, J | 1 |
| Streffer, C | 1 |
| MacKay, RA; Shah, RM | 1 |
| Fuchihata, H; Ozaki, M; Sakai, S; Shigematzu, Y; Tanaka, Y | 1 |
| Miyakawa, K; Morita, M; Sato, Y | 1 |
| Rizki, RM; Rizki, TM | 2 |
| Hasegawa, N; Kawamoto, K; Uemura, T | 1 |
| Chin, LM; Clouse, ME; Khettry, U; Teramoto, K | 1 |
| Grierson, I; Hitchings, RA; Khaw, PT; Porter, A; Rice, NS; Ward, S | 1 |
| Ensminger, WD; Greenberg, HS; Lawrence, TS; Mancini, WR; Stetson, PL; Wagner, JG | 1 |
| Burton, EC; Dusenbury, CE; Ensminger, WD; Jing, HW; Maybaum, J; Shelton, DA; Stetson, PL | 1 |
| Takahashi, H | 1 |
| Katayanagi, N | 1 |
| De Clercq, E; Iigo, M; Miwa, M | 1 |
| De Clercq, E; Hoshi, A; Iigo, M; Nakajima, Y; Nishikata, K | 1 |
| Hieda, S; Ishihara, M; Noguchi, M; Sawaguchi, K; Ueno, N; Yabushita, H | 1 |
| De Clercq, E; Hoshi, A; Iigo, M; Nakajima, Y; Nishikata, K; Odagiri, H; Okudaira, N | 1 |
| Byfield, JE | 1 |
| De Clercq, E; Hoshi, A; Iigo, M; Nakajima, Y | 1 |
| Benedict, WF; Heidelberger, C; Peterson, AR | 1 |
| Hattori, T; Hirano, T; Murata, M; Nakagawa, T; Sakakura, Y; Tashiro, T; Toyota, S; Yamaguchi, N | 1 |
| Vilpo, JA | 1 |
| Araki, E; De Clercq, E; Hoshi, A; Iigo, M; Nakajima, Y | 1 |
| Balzarini, J; De Clercq, E; Keizer, HJ; Landuyt, W; Pauwels, R; van der Schueren, E | 1 |
| Ben-Efraim, S; de Clercq, E; Shoval, S | 1 |
| Ashman, CR; Davidson, RL; Kaufman, ER | 1 |
| Franke, HD | 1 |
| Huebner, RJ; Rhim, JS; Ro, HS; Vernon, ML; Wuu, KD | 1 |
| Bagshaw, MA; Goffinet, DR | 1 |
| Douthit, HA; Rizki, RM; Rizki, TM | 2 |
| Houlihan, RB; Roby, R; Teskey, C | 1 |
| Hiraga, S; Igarashi, K; Yura, T | 1 |
| Hoshino, T; Nagai, M; Sano, K | 1 |
| Golomb, FM | 1 |
| Hanna, C | 1 |
| Beck, A; Tan, YL | 1 |
| Zemla, J | 1 |
| Hoshino, T; Wilson, CB | 1 |
| Aaronson, SA | 1 |
| Lommen, MA; Rizki, RM; Rizki, TM | 1 |
| Birg, F; Meyer, G | 1 |
| Garrett, ER; Nolte, H | 1 |
| Pedicelli, G | 1 |
| Takahashi, M; Tanaka, N | 1 |
| Boutwell, RK; Bowden, GT; Shapas, BG | 1 |
| Boutwell, RK; Bowden, GT | 1 |
| Fischer, HU; Jobski, C; Mundinger, F; Ostertag, C; Vogt, P | 1 |
| Yoshikura, H | 1 |
| Kuroda, Y; Monju, T; Ota, F; Takahashi, M; Tanaka, Y | 1 |
| Babcock, KL; Rusch, HP; Sauer, HW | 1 |
| Cain, JC; Merits, I | 1 |
| Ben-Porat, T; Kamiya, T; Kaplan, AS | 1 |
| Rønne, M | 1 |
| Bradley, TR; Hodgson, GS | 1 |
| Eguchi, S; Matsumura, Y; Nomura, Y; Takayama, K; Terashima, H; Yanagita, T | 1 |
| Miyata, M; Morita, M | 1 |
| Fujimoto, S; Ogawa, M; Sakurai, Y | 1 |
| Ibars, GC; Kauffman, SA; Selick, HE | 1 |
| Higa, T; Ishii, S; Kuroda, Y; Sano, A; Takahashi, M; Tanaka, Y; Yanagisawa, W | 1 |
| Gans, JH; Smuckler, EA | 1 |
| Gebhart, E; Windolph, B; Wopfner, F | 1 |
| Tseng, SC; Zhang, SH | 1 |
| Bloom, LB; Eritja, R; Goodman, MF; Yu, H | 1 |
| Bromberg, J; Chandler, WF; Crane, D; Ensminger, WD; Greenberg, HS; Junck, L; McKeever, P; Page, MA; Sandler, H; Tankanow, R | 1 |
| De Bruijn, EA; De Clercq, E; Keizer, HJ; Tjaden, UR | 1 |
| Akanuma, A; Aoki, Y; Hasezawa, K; Karasawa, K; Muta, N; Nakagawa, K; Onogi, Y; Sakata, K; Sasaki, Y; Terahara, A | 1 |
| Busse, E; Kornhuber, B; Zimmer, G | 1 |
| McLaughlin, BJ; Mohay, J | 1 |
| Lawrence, TS; Robertson, JM; Shewach, DS | 1 |
| Kumada, K; Nakamura, T; Nakano, H; Namatame, K; Sakai, H; Suzuki, T; Takahashi, H | 1 |
| DeRemer, SJ; Ensmiger, WD; Knol, JA; Kuan, HY; Smith, DE; Stetson, PL; Yang, Z | 1 |
| Kato, M; Kuroda, D; Ohyanagi, H; Yasuda, C | 1 |
| Chelladurai, M; Drelichman, A; Hanna, Y; Lobocki, CA; McLaughlin, PW; Pieper, DR; Sultani, M | 1 |
| Clark, PR; Cowsert, LM; Roberts, ML | 1 |
| Blaese, RM; Candotti, F; Wildner, O | 1 |
| Abraham, P; Ashley, SW; Edelman, ER; Jacobs, DO; Kormi, N; Seifert, P; Shen, R; Tavakkolizadeh, A; Whang, EE; Zinner, MJ | 1 |
| Factor, VM; Nagy, P; Paku, S; Sanchez, A; Schnur, J; Teramoto, T; Thorgeirsson, SS | 1 |
| Bonmassar, E; Graziani, G; Portarena, I; Tentori, L | 1 |
| Bödding, M | 1 |
| Mełeń-Mucha, G | 1 |
| Drouin, R; Lavoie, J | 1 |
| Boyer, CR; Karjian, PL; Neuteboom, ST; Pegram, M; Wahl, GM | 1 |
| Balzarini, J; Carangio, A; De Clercq, E; Esnouf, R; Liekens, S; McGuigan, C; Sienaert, R; Van Kuilenburg, A | 1 |
| Barberi-Heyob, M; Didelot, C; Merlin, JL; Mirjolet, JF | 1 |
| Kao, YH; Tseng, HY; Wu, WC | 1 |
| Barberi-Heyob, M; Didelot, C; Merlin, JL; Mirjolet, JF; Ramacci, C; Teiten, MH | 1 |
| Alvarez, E; Dindinger, M; Fey, EG; Ghatpande, A; Jeffers, M; LaRochelle, WJ; Lichenstein, HS; Mesri, M; Peterson, JD; Sonis, ST; Twomlow, N; Valax, P; Yim, Z | 1 |
| KARNOFSKY, DA; SIMMEL, EB | 1 |
| DIPAOLO, JA | 1 |
| SUBAK-SHARPE, H | 1 |
| WILT, FH | 1 |
| Lehnert, S; Li, Y; Owusu, A | 1 |
| Balcerczak, E; Lipa, S; Melen-Mucha, G; Mirowski, M; Mucha, S; Panczyk, M | 1 |
| De Clercq, E | 1 |
| Butler, RN; Cool, JC; Dyer, JL; Geier, MS; Howarth, GS; Xian, CJ | 1 |
| Cool, JC; Foster, BK; Pyragius, T; Xian, CJ | 1 |
| Engelbrecher, A; Häuser, R; Titz, B; Uetz, P | 1 |
| Adachi, M; Hasegawa, Y; Ijichi, K; Ishizaki, K; Kudoh, A; Murakami, S; Nakamura, H; Ogawa, T; Yasui, Y | 1 |
| Fillmore, CM; Kuperwasser, C | 1 |
| Dietrich, J; Han, R; Luebke, A; Mayer-Pröschel, M; Noble, M; Yang, YM | 1 |
| Mełeń-Mucha, G; Motylewska, E | 1 |
| Hofer, S; Krähenbühl, S; Ludwig, C; Rätz Bravo, AE | 1 |
| Li, F; Lu, J; Lu, L | 1 |
| Inoue, A; Kumon, Y; Matsumoto, H; Ohnishi, T; Ohue, S; Smirkin, A; Tagawa, M; Takahashi, H; Tanaka, J; Watanabe, H; Yano, H | 1 |
| Berg, MJ; Gallagher, MJ; Gross, RA; Heckler, CE; Janelsins, MC; Jean-Pierre, P; Morrow, GR; Opanashuk, LA; Roscoe, JA; Thompson, BD | 1 |
| Baena-Cañada, JM; García-Olmedo, O; Jiménez-Bárcenas, R; Martínez, MJ; Muriel-Cueto, P | 1 |
| Emond, MJ; Lauper, JM; Mao, FJ; Monnat, RJ; Sidorova, JM | 1 |
| Fukushima, M; Suzuki, N | 1 |
| Agata, K; Inoue, T; Kitamura, Y; Nishimura, K; Taniguchi, T; Yoshimoto, K | 1 |
| Bennett, G; ElBeltagy, M; Lyons, L; Wigmore, P | 1 |
| Chen, Z; Sun, Z; Wang, M; Xiang, Q; Zhang, R | 1 |
| Abel, G; Barthelmes, J; Dueregger, A; Guggenberger, F; Haunschild, J; Intelmann, D; Klocker, H; Ramoner, R; Sampson, N; Schuh, M; Stecher, G | 1 |
| Arnold, RD; Chavre, S; Chu, CK; De, C; Hagen, FK; Liu, D; Moffat, JF; Singh, US; White, C; Zheng, B | 1 |
| Bremus-Köbberling, E; Feher, K; Junge, K; Klink, CD; Lambertz, A; Neumann, UP; Pich, A; Röth, A; Schmitz, D | 1 |
| García Herrera, AN; Moncayola Vicén, JC | 1 |
9 review(s) available for bromodeoxyuridine and fluorouracil
| Article | Year |
|---|---|
1977 Henry H. Janeway lecture: fundamental mechanisms in combined modality therapy of cancer.
Topics: Animals; Antineoplastic Agents; Bromodeoxyuridine; Dactinomycin; DNA Repair; DNA, Neoplasm; Electrons; Fluorouracil; Humans; Hyperthermia, Induced; Hypoxia; Idoxuridine; Immunotherapy; Mice; Neoplasms; Neoplasms, Experimental; Radiation-Protective Agents; Radiation-Sensitizing Agents; Radiotherapy Dosage; Tourniquets; Ultrasonic Therapy | 1977 |
Oncogenic transformation of C3H/10T1/2 Cl 8 mouse embryo fibroblasts by inhibitors of nucleotide metabolism.
Topics: Animals; Bromodeoxyuridine; Cell Line; Cell Transformation, Neoplastic; Cytidine; Deoxycytidine; Deoxyribonucleotides; DNA; Embryo, Mammalian; Fibroblasts; Floxuridine; Fluorouracil; Idoxuridine; Methotrexate; Mice; Mice, Inbred C3H; Mutation; Thymidine; Trifluridine | 1985 |
The DNA-repair enzyme uracil-DNA glycosylase in the human hematopoietic system.
Topics: Anemia, Megaloblastic; Bromodeoxyuridine; Cell Division; Chromosome Aberrations; DNA Glycosylases; DNA Repair; Fluorouracil; Folic Acid Antagonists; Hematopoiesis; Hematopoietic Stem Cells; Humans; Leukemia; N-Glycosyl Hydrolases; Neoplasm Proteins; Uracil-DNA Glycosidase | 1988 |
Bromodeoxyuridine mutagenesis and deoxyribonucleotide pool imbalance in mammalian cells.
Topics: Animals; Base Composition; Bromodeoxyuridine; Cell Line; Cricetinae; Cytarabine; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Deoxyribonucleotides; DNA; Drug Resistance; Fluorouracil; Hydroxyurea; Melanoma; Mutation; Ribonucleotide Reductases; Sister Chromatid Exchange; Thymidine | 1985 |
Clinical use of radiation sensitizing agents.
Topics: Animals; Antimetabolites, Antineoplastic; Bleomycin; Bromodeoxycytidine; Bromodeoxyuridine; Bromouracil; Carcinoma, Squamous Cell; Dactinomycin; Dose-Response Relationship, Radiation; Floxuridine; Fluorouracil; Head and Neck Neoplasms; Humans; Hydroxyurea; Idoxuridine; Neoplasms; Neoplasms, Experimental; Radiation-Sensitizing Agents | 1974 |
Preclinical studies of chemotherapy and radiation therapy for pancreatic carcinoma.
Topics: Antimetabolites, Antineoplastic; Bromodeoxyuridine; Combined Modality Therapy; Deoxycytidine; Floxuridine; Fluorouracil; Gemcitabine; Idoxuridine; Pancreatic Neoplasms; Radiation-Sensitizing Agents; Tumor Cells, Cultured | 1996 |
EFFECTS OF GROWTH-INHIBITING CHEMICALS ON THE SAND-DOLLAR EMBRYO, ECHINARACHNIUS PARMA.
Topics: Adenine; Animals; Azaguanine; Bromodeoxyuridine; Colchicine; Dinitrophenols; Echinodermata; Embryo, Mammalian; Embryo, Nonmammalian; Enzyme Inhibitors; Floxuridine; Fluorouracil; Growth; Idoxuridine; Mercaptopurine; Pharmacology; Pyrimidines; Sea Urchins | 1963 |
Discovery and development of BVDU (brivudin) as a therapeutic for the treatment of herpes zoster.
Topics: Antimetabolites; Antiviral Agents; Bromodeoxyuridine; Drug Interactions; Europe; Fluorouracil; Herpes Zoster; Herpesvirus 3, Human; Humans; Virus Replication | 2004 |
Interaction between capecitabine and brivudin in a patient with breast cancer.
Topics: Aged; Anemia, Aplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Breast Neoplasms; Bromodeoxyuridine; Capecitabine; Carcinoma, Ductal, Breast; Combined Modality Therapy; Deoxycytidine; Dihydrouracil Dehydrogenase (NADP); Drug Interactions; Fatal Outcome; Female; Fluorouracil; Herpes Zoster; Humans; Onycholysis; Palliative Care; Peripheral Nervous System Diseases; Salvage Therapy; Stomatitis; Tooth Discoloration | 2010 |
2 trial(s) available for bromodeoxyuridine and fluorouracil
| Article | Year |
|---|---|
Radiosensitization with carotid intra-arterial bromodeoxyuridine +/- 5-fluorouracil biomodulation for malignant gliomas.
Topics: Adult; Aged; Brain Neoplasms; Bromodeoxyuridine; Fluorouracil; Glioma; Humans; Infusions, Intra-Arterial; Middle Aged; Radiation-Sensitizing Agents | 1994 |
Histopathological response to preoperative chemotherapy including 5-fluorouracil additionally assessed by immunocytochemical and pharmacologic parameters in patients with advanced gastric cancer.
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bromodeoxyuridine; Cisplatin; Combined Modality Therapy; Drug Administration Schedule; Fluorodeoxyuridylate; Fluorouracil; Humans; Immunohistochemistry; Injections, Intravenous; Preoperative Care; Proliferating Cell Nuclear Antigen; Stomach Neoplasms; Thymidylate Synthase; Tritium | 1996 |
114 other study(ies) available for bromodeoxyuridine and fluorouracil
| Article | Year |
|---|---|
Synthesis and biological activities of some uronic acids, uronates, uronamides, and urononitriles of pyrimidine nucleosides.
Topics: Animals; Cell Division; Cells, Cultured; Chick Embryo; Pyrimidine Nucleosides; Sarcoma 180; Simplexvirus; Streptococcus; Structure-Activity Relationship; Substrate Specificity; Thymidine Kinase; Thymidylate Synthase; Uronic Acids; Virus Replication | 1978 |
Structure-activity relationships of antineoplastic agents in multidrug resistance.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cricetinae; Dactinomycin; Drug Resistance; Leukemia L1210; Mice; Regression Analysis; Structure-Activity Relationship; Tumor Cells, Cultured | 1990 |
Probing the anticancer activity of nucleoside analogues: a QSAR model approach using an internally consistent training set.
Topics: Algorithms; Antineoplastic Agents; Databases, Factual; Discriminant Analysis; Models, Molecular; Nucleosides; Quantitative Structure-Activity Relationship | 2007 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Oncogenic transformation of C3H/10T1/2 clone 8 mouse embryo cells by halogenated pyrimidine nucleosides.
Topics: Animals; Antigens, Viral; Bromodeoxyuridine; Cell Division; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Dose-Response Relationship, Drug; Floxuridine; Fluorouracil; Idoxuridine; Mice; Oncogenic Viruses; Sarcoma, Experimental; Thymidine; Time Factors; Trifluridine | 1976 |
Defective transport of thymidine by cultured cells resistant to 5-bromodeoxyuridine.
Topics: Biological Transport, Active; Bromodeoxyuridine; Drug Resistance; Floxuridine; Fluorouracil; HeLa Cells; Kinetics; Mutation; Ribonucleosides; Thymidine; Thymidine Kinase | 1977 |
Sister-chromatid exchanges and chromosal breakage in patients treated with cytostatics.
Topics: Bromodeoxyuridine; Busulfan; Chromatids; Chromosome Aberrations; Cyclophosphamide; Doxorubicin; Fluorouracil; Humans; Neoplasms | 1979 |
[Mechanism of and dosage in the combination of ionizing radiation and substances in tumor therapy].
Topics: Alkylating Agents; Antibiotics, Antineoplastic; Antineoplastic Agents; Bromodeoxyuridine; Fluorouracil; Halogens; Humans; Neoplasms; Pyrimidine Nucleosides; Radiation-Sensitizing Agents; Radiography | 1978 |
Teratological evaluation of 5-fluorouracil and 5-bromo-2-deoxyuridine on hamster fetuses.
Topics: Animals; Bromodeoxyuridine; Cricetinae; Female; Fetus; Fluorouracil; Gestational Age; Injections, Intramuscular; Injections, Intraperitoneal; Mesocricetus; Pregnancy; Teratogens | 1978 |
[Result of combined therapy of maxillary sinus carcinoma with intra-arterial infusion of BUdR-5 FU and radiation (author's transl)].
Topics: Adult; Aged; Bromodeoxyuridine; Drug Therapy, Combination; Female; Fluorouracil; Humans; Infusions, Intra-Arterial; Male; Maxillary Sinus; Middle Aged; Paranasal Sinus Neoplasms; Radiotherapy Dosage | 1978 |
Combined surgery, radiotherapy and regional chemotherapy in carcinoma of the maxillary sinus.
Topics: Bromodeoxyuridine; Carcinoma; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Fluorouracil; Humans; Injections, Intra-Arterial; Maxillary Sinus; Methods; Paranasal Sinus Neoplasms | 1978 |
Morphogenic effects of halogenated thymidine analogues on Drosophila. VI. Causal analysis of bromodeoxyuridine induced growth lesions.
Topics: Animals; Bromodeoxyuridine; DNA; Dose-Response Relationship, Drug; Drosophila melanogaster; Drug Administration Schedule; Fluorouracil; Growth Disorders; Larva; Phenotype; Thymidine; Wings, Animal | 1975 |
Studies on antitumor effects and mechanism of action of l-hexylcarbamoyl-5-fluorouracil by DNA/BrdU double staining using flow cytometry.
Topics: Antineoplastic Agents; Bromodeoxyuridine; Cell Cycle; DNA; Flow Cytometry; Fluorouracil; Humans; KB Cells; Pharyngeal Neoplasms; Staining and Labeling; Tumor Cells, Cultured | 1992 |
Abrogation of ongoing rejection by bromodeoxyuridine, 5-fluorouracil, and low-dose irradiation in heterotopic rat heart transplantation.
Topics: Animals; Bromodeoxyuridine; Combined Modality Therapy; Dose-Response Relationship, Radiation; Fluorescence; Fluorouracil; Graft Rejection; Heart Transplantation; Male; Rats; Rats, Inbred ACI; Rats, Inbred Lew; Transplantation, Heterotopic; Ultraviolet Rays | 1992 |
The long-term effects of 5-fluorouracil and sodium butyrate on human Tenon's fibroblasts.
Topics: Adolescent; Bromodeoxyuridine; Butyrates; Butyric Acid; Cell Count; Cell Survival; Cells, Cultured; Eye; Fascia; Fibroblasts; Fluorouracil; Humans; Longitudinal Studies | 1992 |
Variability of 5-bromo-2'-deoxyuridine incorporation into DNA of human glioma cell lines and modulation with fluoropyrimidines.
Topics: Bromodeoxyuridine; DNA, Neoplasm; Floxuridine; Fluorouracil; Glioma; Humans; Tumor Cells, Cultured | 1991 |
Divergent patterns of incorporation of bromodeoxyuridine and iododeoxyuridine in human colorectal tumor cell lines.
Topics: Bromodeoxyuridine; Cell Division; Colorectal Neoplasms; DNA, Neoplasm; Floxuridine; Fluorouracil; Gas Chromatography-Mass Spectrometry; Humans; Idoxuridine; Radiation-Sensitizing Agents; Tumor Cells, Cultured | 1991 |
[A combined therapy for maxillary cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bromodeoxyuridine; Combined Modality Therapy; Female; Fluorouracil; Humans; Injections, Intra-Arterial; Lymph Node Excision; Male; Maxillary Neoplasms; Middle Aged; Survival Rate | 1991 |
[An experimental study of anticancer agent sensitivity test in human gastric cancer cell lines by flow cytometry].
Topics: Antibodies, Monoclonal; Antineoplastic Agents; Bromodeoxyuridine; Cell Cycle; Cisplatin; DNA, Neoplasm; Doxorubicin; Drug Screening Assays, Antitumor; Flow Cytometry; Fluorouracil; Humans; Mitomycin; Mitomycins; Stomach Neoplasms; Tumor Cells, Cultured | 1990 |
Optimal treatment regimens for 5'-deoxy-5-fluorouridine, with or without (E)-5-(2-bromovinyl)-2'-deoxyuridine, against various tumors in mice.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Antiviral Agents; Bromodeoxyuridine; Colonic Neoplasms; Drug Therapy, Combination; Floxuridine; Fluorouracil; Liver Neoplasms; Lung Neoplasms; Mice; Mice, Inbred BALB C; Pentosyltransferases; Prodrugs; Pyrimidine Phosphorylases | 1990 |
Effect of (E)-5-(2-bromovinyl)-2'-deoxyuridine on life-span and 5-fluorouracil metabolism in mice with hepatic metastases.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Bromodeoxyuridine; Fluorouracil; Life Expectancy; Liver Neoplasms, Experimental; Mice; Mice, Inbred Strains | 1990 |
[Experimental study on the effect of UFT with concomitant radiotherapy of uterine cervical cancer].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bromodeoxyuridine; Carcinoma, Squamous Cell; Cell Division; Cell Line; Combined Modality Therapy; DNA Polymerase II; Female; Fluorouracil; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Tegafur; Tumor Cells, Cultured; Uracil; Uterine Cervical Neoplasms | 1989 |
Enhancing effect of bromovinyldeoxyuridine on antitumor activity of 5'-deoxy-5-fluorouridine against adenocarcinoma 755 in mice. Correlation with pharmacokinetics of plasma 5-fluorouracil levels.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Bromodeoxyuridine; Chromatography, High Pressure Liquid; Drug Synergism; Floxuridine; Fluorouracil; Half-Life; Male; Mice; Neoplasm Transplantation; Spectrophotometry, Ultraviolet | 1989 |
Combined use of drugs and radiation in the treatment of liver metastases.
Topics: Amifostine; Bromodeoxyuridine; Combined Modality Therapy; Floxuridine; Fluorouracil; Humans; Infusions, Intra-Arterial; Liver; Liver Neoplasms | 1986 |
Enhancing effect of bromovinyldeoxyuridine on antitumor activity of 5-fluorouracil and ftorafur against adenocarcinoma 755 in mice.
Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Bromodeoxyuridine; Cysteine; Drug Evaluation, Preclinical; Drug Synergism; Fluorouracil; Male; Mice; Tegafur | 1987 |
[Continuous superselective intra-arterial infusion with BUdR and 5 FU in combination with radiotherapy in the treatment of head and neck tumors].
Topics: Bromodeoxyuridine; Combined Modality Therapy; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Infusions, Intra-Arterial; Middle Aged; Radiotherapy Dosage | 1988 |
Enhancing effect of bromovinyldeoxyuridine on antitumor activity of 5-fluorouracil against adenocarcinoma 755 in mice. Increased therapeutic index and correlation with increased plasma 5-fluorouracil levels.
Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Bromodeoxyuridine; Chromatography, High Pressure Liquid; Drug Synergism; Fluorouracil; Male; Mice | 1988 |
Combined effects of bromovinyldeoxyuridine and fractionated or continuous administration of 5-fluorouracil in P388 leukemia-bearing mice.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Bromodeoxyuridine; Female; Fluorouracil; Lethal Dose 50; Leukemia P388; Leukemia, Experimental; Male; Mice; Mice, Inbred DBA | 1988 |
Enhancing effect of bromovinyldeoxyuridine on antitumour activity of 5-fluorouracil in mice bearing MOPC-315 plasmacytomas.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bromodeoxyuridine; Dose-Response Relationship, Drug; Drug Interactions; Fluorouracil; Mice; Mice, Inbred BALB C; Plasmacytoma | 1986 |
[The use of radiosensitizing agents in radiotherapy].
Topics: Brain Neoplasms; Bromodeoxyuridine; Dactinomycin; DNA; Fluorouracil; Glycogen; Humans; Neoplasms; Oxygen; Radiation-Sensitizing Agents; RNA; Vitamin K | 1972 |
Induction of guinea pig leukemia-like virus from cultured guinea pigs cells.
Topics: Animals; Antigens, Viral; Bromodeoxyuridine; Cell Transformation, Neoplastic; Cells, Cultured; Centrifugation, Density Gradient; Clone Cells; Complement Fixation Tests; Cytochalasin B; Enzyme Activation; Fibroblasts; Fluorouracil; Guinea Pigs; Hybrid Cells; Idoxuridine; Kidney; Mercaptopurine; Methylcholanthrene; Microscopy, Electron; Retroviridae; RNA-Directed DNA Polymerase; Spleen; Time Factors | 1974 |
Morphogenic effects of halogenated thymidine analogues on Drosophila. I. Quantitative analysis of lesions induced by 5-bromodeoxyuridine and 5-fluorouracil.
Topics: Animals; Autoradiography; Bromodeoxyuridine; Cell Nucleus; Deoxyribonucleases; Drosophila melanogaster; Female; Fluorouracil; Larva; Male; Mutation; Sex Chromosomes; Tritium; Wings, Animal | 1972 |
Inhibition of plaque formation by myxoma and fibroma viruses with pyrimidine analogues.
Topics: Antiviral Agents; Benzimidazoles; Bromodeoxyuridine; Culture Techniques; Cytosine; DNA, Viral; Fibroma; Floxuridine; Fluorouracil; Idoxuridine; Mercaptopurine; Methotrexate; Myxoma virus; Nucleosides; Oncogenic Viruses; Thiosemicarbazones; Thymine | 1965 |
A deoxythymidine kinase-deficient mutant of Escherichia coli. I. Isolation and some properties.
Topics: Bromodeoxyuridine; Carbon Isotopes; Chromatography, Paper; Coliphages; Escherichia coli; Floxuridine; Fluorouracil; Mutation; Thymidine Kinase | 1967 |
Radiosensitization of brain tumor cells with a thymidine analogue (bromouridine).
Topics: Astrocytoma; Brain Neoplasms; Bromodeoxyuridine; Culture Techniques; DNA; Floxuridine; Fluorouracil; Follow-Up Studies; Glioma; Humans; Meningioma; Methotrexate; Oligodendroglioma; Radiation-Sensitizing Agents; Thymidine | 1968 |
Perfusion and infusion chemotherapy for cancer of the head and neck.
Topics: Antineoplastic Agents; Bromodeoxyuridine; Carotid Arteries; Catheterization; Chemotherapy, Cancer, Regional Perfusion; Cyclophosphamide; Dactinomycin; DNA; Floxuridine; Fluorouracil; Head; Humans; Infusions, Parenteral; Melphalan; Methods; Neck; Nitrogen Mustard Compounds | 1964 |
Incorporation of idoxuridine analogs into corneal herpes simplex virus.
Topics: Animals; Autoradiography; Bromodeoxyuridine; Cornea; DNA, Viral; Epithelium; Floxuridine; Fluorouracil; Herpes Simplex; Idoxuridine; Keratitis, Dendritic; Ophthalmic Solutions; Rabbits; Thymidine; Tritium; Uracil | 1972 |
Complex formation of uracil, 2'-deoxyuridine and their 5-halogenated derivatives.
Topics: Bromodeoxyuridine; Bromouracil; Chemical Phenomena; Chemistry; Copper; Deoxyuridine; Drug Stability; Floxuridine; Fluorouracil; Idoxuridine; Mathematics; Nickel; Potentiometry; Silver; Uracil | 1973 |
Effect of 5-fluorouracil and 5-bromo-2'-deoxyuridine on the induction of thymidine kinase in polyoma virus-infected mouse embryo cells.
Topics: Animals; Bromodeoxyuridine; Depression, Chemical; DNA, Viral; Embryo, Mammalian; Enzyme Induction; Fluorouracil; Mice; Polyomavirus; RNA, Messenger; Thymidine Kinase; Tritium; Virus Replication | 1968 |
Current trends in the chemotherapy of brain tumors with special reference to glioblastomas.
Topics: Alkaloids; Antibiotics, Antineoplastic; Antineoplastic Agents; Azaguanine; Blood Vessel Prosthesis; Blood-Brain Barrier; Brain; Brain Neoplasms; Bromodeoxyuridine; Cell Division; Cell Transformation, Neoplastic; Disease Models, Animal; Fluorouracil; Glioblastoma; Humans; Injections, Intra-Arterial; Injections, Spinal; Mechlorethamine; Methotrexate; Nitroso Compounds; Thiotepa; Time Factors; Urea; Vincristine | 1969 |
Chemical induction of focus-forming virus from nonproducer cells transformed by murine sarcoma virus.
Topics: Amines; Animals; Antigens, Viral; Bromodeoxyuridine; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Cytosine Nucleotides; Deoxyuridine; Fluorouracil; Gammaretrovirus; Helper Viruses; Iodine; Mercaptopurine; Mice; Moloney murine leukemia virus; Rats; Rauscher Virus; Time Factors; Virus Replication | 1971 |
Ultrastructural effects of 5-bromodeoxyuridine and 5-fluorouracil in Drosophila.
Topics: Adipose Tissue; Animals; Bromodeoxyuridine; Cell Nucleus; Cytoplasm; Drosophila melanogaster; Fluorouracil; Inclusion Bodies; Larva; Microscopy, Electron; Mutation | 1973 |
Effect of various inhibitors on the expression of polyoma virus-induced surface antigen in BHK21 cells.
Topics: Amino Acids; Animals; Antigens, Viral; Autoradiography; Bromodeoxyuridine; Carbon Radioisotopes; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Cycloheximide; Cytarabine; DNA, Viral; Fluorescent Antibody Technique; Fluorouracil; Kidney; Microscopy, Fluorescence; Mitomycins; Polyomavirus; Puromycin; RNA, Viral; Thymidine; Time Factors; Tritium; Viral Proteins | 1973 |
Kinetics and mechanisms of drug action on microorganisms. XIV. The action of fluorouracil, other uracils and derived nucleosides on the microbial kinetics of Escherichia coli.
Topics: Bromodeoxyuridine; Bromouracil; Chlorine; Culture Media; Deoxyribonucleosides; Escherichia coli; Fluorouracil; Hydrogen-Ion Concentration; Kinetics; Nucleosides; Osmolar Concentration; Protein Binding; Time Factors; Uracil | 1972 |
Morphogenic effects of halogenated thymidine analogs on Drosophila. II. Incorporation of 5 -bromodeoxyuridine into DNA.
Topics: Autoradiography; Bromodeoxyuridine; Cell Nucleus; Centrifugation, Density Gradient; Densitometry; DNA; Drosophila melanogaster; Drug Interactions; Fluorouracil; Germ Cells; Larva; Thymidine; Tritium; Ultracentrifugation | 1972 |
[Radiosensitizing chemical agents. Radiobiological reasons and prospects for their use].
Topics: Acetates; Animals; Bromodeoxyuridine; Bromouracil; Carcinoma, Ehrlich Tumor; Cell Membrane; Cosmic Radiation; DNA; Fluorouracil; Iodine; Mice; Naphthoquinones; Pyrimidines; Radiation Effects; Radiation-Sensitizing Agents; Radiotherapy Dosage | 1972 |
[Trial and results of improved radiotherapy for cancer. 5. Radiotherapy with simultaneous administration of radio-sensitizing agents. Administration of halogenated pyrimidine].
Topics: Bromodeoxyuridine; Fluorouracil; Humans; Neoplasms; Radiation-Sensitizing Agents; Tongue Neoplasms | 1972 |
The role of thymidylate synthetase inhibitors in bromodeoxyuridine-induced neoplasia in Drosophila.
Topics: Animals; Bromodeoxyuridine; Centrifugation, Density Gradient; DNA; Drosophila; Fluorine; Fluorouracil; Idoxuridine; Larva; Methotrexate; Methyltransferases; Neoplasms, Experimental; Thymidine; Thymidylate Synthase; Tritium | 1973 |
The binding of 7,12-dimethylbenz(a)anthracene to replicating and non-replicating DNA in mouse skin.
Topics: Acetone; Animals; Benz(a)Anthracenes; Binding Sites; Bromodeoxyuridine; Carbon Radioisotopes; Centrifugation, Density Gradient; Croton Oil; DNA; DNA Replication; Female; Fluorouracil; Mice; Receptors, Drug; Skin; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Time Factors; Tritium | 1974 |
The replication of mouse skin epidermal DNA to which is bound 7,12-dimethylbenz(a)anthracene.
Topics: Animals; Benz(a)Anthracenes; Binding Sites; Bromodeoxyuridine; Centrifugation, Density Gradient; Chromatography, Thin Layer; DNA; DNA Replication; Fluorouracil; Hydrogen-Ion Concentration; Mice; Receptors, Drug; Skin; Spectrophotometry, Ultraviolet; Templates, Genetic; Time Factors; Tritium | 1974 |
[Clinical and experimental results of interstitial Brachy-Curie-therapy combined with radiation sensitizing agents in infiltrative growing brain neoplasms].
Topics: Animals; Brain Neoplasms; Bromodeoxyuridine; Carcinosarcoma; Cytidine; Fluorouracil; Guanosine; Iridium; Methotrexate; Neoplasms, Experimental; Radiation-Sensitizing Agents; Rats; Thymine | 1972 |
Effect of 5-fluorouracil on ultraviolet inactivation of virus production by murine sarcoma-leukemia virus complex carrier cells.
Topics: Animals; Bromodeoxyuridine; Cell Line; Cell Survival; Fluorouracil; Kidney; Mice; Moloney murine leukemia virus; Radiation Effects; RNA, Viral; Time Factors; Ultraviolet Rays; Virus Replication | 1972 |
[Application of radiosensitizer, 5-bromodeoxyuridine, to head and neck tumors].
Topics: Bromodeoxyuridine; Fluorouracil; Humans; Injections, Intra-Arterial; Iodine Isotopes; Male; Maxillary Neoplasms; Mouth Mucosa; Radiation-Sensitizing Agents; Time Factors; Tongue Neoplasms | 1969 |
Sporulation in Physarum polycephalum: a model system for studies on differentiation.
Topics: Acridines; Bromodeoxyuridine; Cell Differentiation; Culture Media; Cycloheximide; Dactinomycin; DNA; Fluorouracil; Light; Myxomycetes; Plant Proteins; RNA; Spores; Time Factors | 1969 |
Loss of labelled DNA from rat brain following injections of precursors with high specific radioactivity. II. DNA labelled with 5-[131I]iodo-2'-deoxyuridine and 5-[82Br]bromo-2'-deoxyuridine.
Topics: Brain; Bromine; Bromodeoxyuridine; Centrifugation, Density Gradient; Chromatography, Ion Exchange; DNA; Fluorouracil; Hot Temperature; Iodine; Iodine Isotopes; Nucleic Acid Denaturation; Radioisotopes; Tritium; Uridine | 1970 |
Control of certain aspects of the infective process by progeny viral DNA.
Topics: Animals; Bromodeoxyuridine; DNA; DNA, Viral; Enzymes; Fluorouracil; Herpesviridae; In Vitro Techniques; Kidney; Protein Biosynthesis; Puromycin; Rabbits; Thymidine; Virus Cultivation | 1965 |
Fluorouracil synchronization of human lymphocyte cultures. Induction of high resolution R-banding by simultaneous in vitro exposure to 5-bromodeoxyuridine/Hoechst 33258.
Topics: Bisbenzimidazole; Bromodeoxyuridine; Chromosome Banding; Fluorouracil; Humans; Interphase; Lymphocytes | 1984 |
In vivo kinetic status of hematopoietic stem and progenitor cells as inferred from labeling with bromodeoxyuridine.
Topics: Animals; Blood Platelets; Bone Marrow; Bromodeoxyuridine; Cell Survival; Fluorouracil; Hematopoietic Stem Cells; Kinetics; Mice; Mice, Inbred BALB C; Ultraviolet Rays | 1984 |
[Review of intra-arterial infusion-radiation therapy for lingual cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bromodeoxyuridine; Combined Modality Therapy; Female; Fluorouracil; Humans; Infusions, Intra-Arterial; Lymphatic Metastasis; Male; Middle Aged; Tongue Neoplasms | 1984 |
[Treatment of maxillary cancer].
Topics: Bromodeoxyuridine; Carcinoma, Squamous Cell; Combined Modality Therapy; Fluorouracil; Humans; Infusions, Intra-Arterial; Maxillary Sinus; Paranasal Sinus Neoplasms; Prognosis; Radiotherapy Dosage | 1984 |
Hypothetical mechanism of therapeutic synergism induced by the combination of 6-thioguanine and 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-1-(2-chloroethyl)-1-nitrosourea hydrochloride.
Topics: Animals; Antineoplastic Agents; Bromodeoxyuridine; Drug Evaluation, Preclinical; Drug Therapy, Combination; Female; Fluorouracil; Leukemia L1210; Methotrexate; Mice; Mice, Inbred Strains; Nimustine; Nitrosourea Compounds; Thioguanine | 1982 |
Inhibition of two homeotic mutants of Drosophila by 5-bromodeoxyuridine and fluorouracil.
Topics: Animals; Bromodeoxyuridine; Drosophila; Female; Fluorouracil; Genes, Dominant; Genes, Recessive; Larva; Mutation; Phenotype | 1981 |
[Role of radiosensitizer for treatment of malignant tumors of the maxillary antrum (author's transl)].
Topics: Bromodeoxyuridine; Fluorouracil; Humans; Infusions, Intra-Arterial; Maxillary Sinus; Paranasal Sinus Neoplasms; Radiation-Sensitizing Agents; Radiotherapy Dosage | 1980 |
The in vivo incorporation of triated thymidine into liver cell nuclear DNA in mice treated chronically with carbon tetrachloride or with diethylnitrosamine.
Topics: Animals; Bromodeoxyuridine; Carbon Tetrachloride Poisoning; Cell Nucleus; Diethylnitrosamine; DNA; DNA Repair; Fluorouracil; Hydroxyurea; Liver; Mice; Nitrosamines; Thymidine | 1980 |
Chromosome studies on lymphocytes of patients under cytostatic therapy. II. Studies Using the BUDR-labelling technique in cytostatic interval therapy.
Topics: Adult; Aged; Antineoplastic Agents; Bromodeoxyuridine; Cell Division; Cells, Cultured; Chromosomes, Human; Female; Fluorouracil; Humans; Kinetics; Lymphocytes; Male; Metaphase; Middle Aged; Semustine; Sister Chromatid Exchange; Vincristine | 1980 |
Limbal epithelium is more resistant to 5-fluorouracil toxicity than corneal epithelium.
Topics: Animals; Bromodeoxyuridine; Cell Division; Cell Survival; Cells, Cultured; Cornea; DNA Replication; Drug Resistance; Epithelium; Fluorouracil; Limbus Corneae; Male; Rabbits; Stem Cells | 1995 |
Ionization of bromouracil and fluorouracil stimulates base mispairing frequencies with guanine.
Topics: Base Sequence; Bromodeoxyuridine; Bromouracil; DNA; Floxuridine; Fluorouracil; Guanine; Hydrogen Bonding; Hydrogen-Ion Concentration; Ions; Molecular Sequence Data; Nucleic Acid Heteroduplexes; RNA-Directed DNA Polymerase; Templates, Genetic; Thymine Nucleotides | 1993 |
Inhibition of fluorouracil catabolism in cancer patients by the antiviral agent (E)-5-(2-bromovinyl)-2'-deoxyuridine.
Topics: Adult; Aged; Antiviral Agents; Bromodeoxyuridine; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasms | 1994 |
Analysis of the results of combined therapy for maxillary carcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bromodeoxyuridine; Carcinoma, Squamous Cell; Combined Modality Therapy; Fluorouracil; Follow-Up Studies; Humans; Infusions, Intra-Arterial; Maxillary Sinus Neoplasms; Radiotherapy Dosage; Salvage Therapy; Survival Rate | 1993 |
Intracellular changes of HeLa cells after single or repeated treatment with cytostatics.
Topics: Antineoplastic Agents; Bromodeoxyuridine; Cell Division; Cell Membrane; Cisplatin; Cysteine; Doxorubicin; Fluorouracil; Glutathione; HeLa Cells; Humans; Membrane Fluidity; Membranes; Protein Kinase C | 1993 |
Corneal endothelial wound repair in normal and mitotically inhibited cultures.
Topics: Animals; Antimetabolites; Bromodeoxyuridine; Cattle; Cell Division; Cells, Cultured; Connexin 43; Cytoskeletal Proteins; Cytoskeleton; DNA; Endothelium, Corneal; Fluorescent Antibody Technique; Fluorouracil; Mitosis; Wound Healing | 1995 |
Regional pharmacokinetics of 5-bromo-2'-deoxyuridine and 5-fluorouracil in dogs: hepatic arterial versus portal venous infusions.
Topics: Animals; Antimetabolites, Antineoplastic; Bromodeoxyuridine; Dogs; Female; Fluorouracil; Hepatic Artery; Infusions, Intra-Arterial; Infusions, Intravenous; Liver; Male; Portal Vein; Regional Blood Flow | 1996 |
Experimental studies on potentiation of the antitumor activity of 5-fluorouracil with 3'-azido-3'-deoxythymidine for the gastric cancer cell line MKN28 in vivo.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bromodeoxyuridine; Drug Synergism; Female; Fluorouracil; Humans; Mice; Mice, Inbred BALB C; Stomach Neoplasms; Thymidine Kinase; Tumor Cells, Cultured; Zidovudine | 1997 |
Bromodeoxyuridine improves the cytotoxic effect of cisplatin: a comparison with 5-fluorouracil.
Topics: Animals; Antineoplastic Agents; Bromodeoxyuridine; Cisplatin; Drug Synergism; Fluorouracil; Male; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Tumor Cells, Cultured | 1997 |
A novel drug screening assay for papillomavirus specific antiviral activity.
Topics: Antiviral Agents; Bromodeoxyuridine; Butyrates; Butyric Acid; DNA Replication; DNA, Viral; Drug Evaluation, Preclinical; Fluorouracil; Humans; Interferon-alpha; Kinetics; Oligonucleotides, Antisense; Papillomaviridae; Plasmids; Thionucleotides; Tumor Cells, Cultured; Virus Replication | 1998 |
Enzyme prodrug gene therapy: synergistic use of the herpes simplex virus-cellular thymidine kinase/ganciclovir system and thymidylate synthase inhibitors for the treatment of colon cancer.
Topics: Antiviral Agents; Bromodeoxyuridine; Colonic Neoplasms; Combined Modality Therapy; Enzyme Inhibitors; Fluorouracil; Ganciclovir; Genetic Therapy; Humans; Quinazolines; Simplexvirus; Thiophenes; Thymidine Kinase; Thymidylate Synthase; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1999 |
Glucagon-like peptide 2: a new treatment for chemotherapy-induced enteritis.
Topics: Animals; Antimetabolites, Antineoplastic; Body Weight; Bromodeoxyuridine; Enteritis; Fluorouracil; Glucagon-Like Peptide 2; Glucagon-Like Peptides; Intestinal Mucosa; Jejunum; Male; Morbidity; Peptides; Rats; Rats, Sprague-Dawley | 2000 |
Reconstitution of liver mass via cellular hypertrophy in the rat.
Topics: Animals; Bromodeoxyuridine; Cell Division; Dexamethasone; DNA; Fluorouracil; Glucocorticoids; Hepatectomy; Hepatocytes; Hypertrophy; Liver; Liver Regeneration; Male; Rats; Rats, Inbred F344 | 2001 |
Combined effects of adenovirus-mediated wild-type p53 transduction, temozolomide and poly (ADP-ribose) polymerase inhibitor in mismatch repair deficient and non-proliferating tumor cells.
Topics: Adenoviridae; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Apoptosis; Base Pair Mismatch; Blotting, Western; Bromodeoxyuridine; Cell Division; Dacarbazine; DNA Repair; DNA Replication; Enzyme Inhibitors; Fluorouracil; Gene Deletion; Genetic Vectors; Humans; Jurkat Cells; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Protein Transport; Quinazolines; Temozolomide; Thiophenes; Transduction, Genetic; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2001 |
Reduced store-operated Ca(2+) currents in rat basophilic leukaemia cells cultured under serum-free conditions.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Aphidicolin; Bromodeoxyuridine; Calcium; Cell Cycle; Cell Division; Culture Media, Serum-Free; Enzyme Inhibitors; Fluorouracil; Guanosine 5'-O-(3-Thiotriphosphate); Inositol 1,4,5-Trisphosphate; Leukemia; Patch-Clamp Techniques; Potassium; Potassium Channels; Rats; Time Factors; Tretinoin; Tumor Cells, Cultured | 2001 |
Effects of short term treatment with pentagastrin, proglumide, tamoxifen given separately or together with 5-fluorouracil on the growth in the murine transplantable Colon 38 cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bromodeoxyuridine; Cell Division; Colonic Neoplasms; Fluorouracil; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Pentagastrin; Proglumide; Tamoxifen | 2001 |
Lymphoblasts already in the DNA synthesis phase of the cell cycle can be reversibly arrested at the R/G transition.
Topics: Bromodeoxyuridine; Cell Cycle; Cell Line, Transformed; Chromosome Banding; Chromosomes, Human; DNA; DNA Replication; Flow Cytometry; Fluorouracil; Humans; Karyotyping; Kinetics; Lymphocyte Activation; Lymphocytes; Methotrexate; Mimosine; S Phase; Thymidine | 2001 |
Nucleoside transport inhibitors, dipyridamole and p-nitrobenzylthioinosine, selectively potentiate the antitumor activity of NB1011.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Breast Neoplasms; Bromodeoxyuridine; Carrier Proteins; Cell Survival; Colonic Neoplasms; Dipyridamole; Drug Resistance, Neoplasm; Drug Synergism; Fluorouracil; Humans; Membrane Proteins; Nucleoside Transport Proteins; Quinazolines; Thioinosine; Thiophenes; Thymidylate Synthase; Tumor Cells, Cultured | 2002 |
Lack of susceptibility of bicyclic nucleoside analogs, highly potent inhibitors of varicella-zoster virus, to the catabolic action of thymidine phosphorylase and dihydropyrimidine dehydrogenase.
Topics: Animals; Antiviral Agents; Binding Sites; Bromodeoxyuridine; Bromouracil; Dihydrouracil Dehydrogenase (NADP); Drug Interactions; Escherichia coli; Fluorouracil; Herpesvirus 3, Human; Heterocyclic Compounds, 2-Ring; Humans; Mice; Models, Molecular; Nucleosides; Oxidoreductases; Substrate Specificity; Thymidine Phosphorylase | 2002 |
G(1)/S but not G(0)/G(1)cell fraction is related to 5-fluorouracil cytotoxicity.
Topics: Adenocarcinoma; Antimetabolites; Antimetabolites, Antineoplastic; Breast Neoplasms; Bromodeoxyuridine; Coloring Agents; Female; Flow Cytometry; Fluorouracil; G1 Phase; Head and Neck Neoplasms; Humans; Pancreatic Neoplasms; Propidium; Resting Phase, Cell Cycle; S Phase; Tumor Cells, Cultured | 2002 |
The cell cycle distribution of cultured human retinal pigmented epithelial cells under exposure of anti-proliferative drugs.
Topics: Bromodeoxyuridine; Cell Cycle; Cell Division; Cell Line; Daunorubicin; Dexamethasone; Fluorouracil; Glucocorticoids; Humans; Mitomycin; Nucleic Acid Synthesis Inhibitors; Pigment Epithelium of Eye | 2003 |
Oncoprotein expression of E6 and E7 does not prevent 5-fluorouracil (5FU) mediated G1/S arrest and apoptosis in 5FU resistant carcinoma cell lines.
Topics: Apoptosis; Blotting, Western; Bromodeoxyuridine; Cell Cycle; Cell Line; Cell Line, Tumor; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA; DNA Damage; DNA-Binding Proteins; Drug Resistance, Neoplasm; Flow Cytometry; Fluorouracil; G1 Phase; Humans; Inhibitory Concentration 50; Microscopy, Fluorescence; Nuclear Proteins; Oncogene Proteins; Oncogene Proteins, Viral; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; S Phase; Time Factors; Tumor Suppressor Protein p53 | 2003 |
Preclinical characterization of CG53135 (FGF-20) in radiation and concomitant chemotherapy/radiation-induced oral mucositis.
Topics: Animals; Bromodeoxyuridine; Cheek; Coloring Agents; Cricetinae; Dose-Response Relationship, Drug; Fibroblast Growth Factors; Fluorouracil; Humans; Jejunum; Male; Mesocricetus; Mouth Mucosa; Mucous Membrane; Radiation Injuries; Recombinant Proteins; Stomatitis; Time Factors | 2003 |
POLYDACTYLISM IN THE OFFSPRING OF MICE INJECTED WITH 5-BROMODEOXYURIDINE.
Topics: Abnormalities, Drug-Induced; Animals; Blood Chemical Analysis; Bromodeoxyuridine; Family; Female; Fluorouracil; Foot; Foot Diseases; Humans; Mice; Nucleosides; Polydactyly; Pregnancy; Pregnancy, Animal; Research; Toxicology | 1964 |
BIOCHEMICALLY MARKED VARIANTS OF THE SYRIAN HAMSTER FIBROBLAST CELL LINE BHK21 AND ITS DERIVATIVES.
Topics: 2-Aminopurine; Amphotericin B; Animals; Antineoplastic Agents; Azaguanine; Bromodeoxyuridine; Carbon Isotopes; Cell Division; Cell Line; Cricetinae; Dactinomycin; Fibroblasts; Floxuridine; Fluorouracil; Hexoses; Hypoxanthines; Mercaptopurine; Mesocricetus; Metabolism; Mitomycin; Mitomycins; Mutation; Nucleosides; Pharmacology; Puromycin; Research; Thioguanine; Tissue Culture Techniques; Tritium; Vinblastine | 1965 |
REGULATION OF THE INITIATION OF CHICK EMBRYO HEMOGLOBIN SYNTHESIS.
Topics: Azaguanine; Bromodeoxyuridine; Chick Embryo; Dactinomycin; Fluorouracil; Hemoglobins; Mesoderm; Molecular Biology; Nucleosides; Pharmacology; Proteins; Puromycin; Research; RNA; Tissue Culture Techniques | 1965 |
Treatment of intracranial rat glioma model with implant of radiosensitizer and biomodulator drug combined with external beam radiotherapy.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Brain Neoplasms; Bromodeoxyuridine; Cell Line, Tumor; Combined Modality Therapy; Drug Combinations; Drug Implants; Fluorouracil; Glioma; Immunologic Factors; Methotrexate; Phosphonoacetic Acid; Radiation-Sensitizing Agents; Rats | 2004 |
Expression of p65 gene in experimental colon cancer under the influence of 5-fluorouracil given alone and in combination with hormonal modulation.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bromodeoxyuridine; Carrier Proteins; Cell Division; Cell Line, Tumor; Colonic Neoplasms; Coloring Agents; Estrogen Antagonists; Fluorouracil; Gene Expression Regulation, Neoplastic; Hormones; In Situ Nick-End Labeling; Male; Mice; Mice, Inbred C57BL; Neoplasm Proteins; Neoplasm Transplantation; Peptides, Cyclic; Reverse Transcriptase Polymerase Chain Reaction; Somatostatin; Tamoxifen; Transcription Factor RelA | 2004 |
Pre-treatment with insulin-like growth factor-I partially ameliorates 5-fluorouracil-induced intestinal mucositis in rats.
Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Body Weight; Bromodeoxyuridine; Cell Proliferation; Coloring Agents; Duodenum; Fluorouracil; Ileum; Inflammation; Insulin-Like Growth Factor I; Intestinal Mucosa; Intestine, Small; Jejunum; Male; Organ Size; Rats; Rats, Sprague-Dawley; Sucrase; Sucrose; Time Factors | 2005 |
Damage and recovery of the bone growth mechanism in young rats following 5-fluorouracil acute chemotherapy.
Topics: Animals; Apoptosis; Base Sequence; Bone Development; Bromodeoxyuridine; DNA Primers; Fluorouracil; Gene Expression; Growth Plate; Male; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley | 2006 |
The Escherichia coli protein YjjG is a house-cleaning nucleotidase in vivo.
Topics: Azacitidine; Bromodeoxyuridine; Decitabine; Deoxyuridine; DNA Damage; Escherichia coli; Escherichia coli Proteins; Fluorouracil; Models, Biological; Molecular Structure; Mutation; N-Glycosyl Hydrolases; Nucleotidases; Orotic Acid; Substrate Specificity; Thymidine Monophosphate; Uridine | 2007 |
Pretreatment with 5-FU enhances cisplatin cytotoxicity in head and neck squamous cell carcinoma cells.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Bromodeoxyuridine; Cell Cycle; Cell Line, Tumor; Cisplatin; Colony-Forming Units Assay; Flow Cytometry; Fluorouracil; Head and Neck Neoplasms; Humans; Immunohistochemistry; Neoplasms, Squamous Cell; Proliferating Cell Nuclear Antigen | 2008 |
Human breast cancer cell lines contain stem-like cells that self-renew, give rise to phenotypically diverse progeny and survive chemotherapy.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Bromodeoxyuridine; CD24 Antigen; Cell Line, Tumor; Cell Survival; Drug Resistance, Neoplasm; Female; Flow Cytometry; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Hyaluronan Receptors; Membrane Proteins; Mice; Mice, Inbred NOD; Mice, SCID; Neoplastic Stem Cells; Paclitaxel; Phenotype | 2008 |
Systemic 5-fluorouracil treatment causes a syndrome of delayed myelin destruction in the central nervous system.
Topics: Action Potentials; Animals; Antineoplastic Agents; Auditory Pathways; Bromodeoxyuridine; Cell Line, Tumor; Central Nervous System; Fluorouracil; Humans; In Situ Nick-End Labeling; Indoles; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Myelin Sheath; Rats; Stem Cells; Tetrazolium Salts; Thiazoles | 2008 |
Estrone and progesterone inhibit the growth of murine MC38 colon cancer line.
Topics: Animals; Bromodeoxyuridine; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Estrone; Fluorouracil; Mice; Progesterone | 2009 |
Fatal drug-drug interaction of brivudine and capecitabine.
Topics: Adverse Drug Reaction Reporting Systems; Aged, 80 and over; Antimetabolites, Antineoplastic; Antiviral Agents; Bromodeoxyuridine; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Fatal Outcome; Female; Fluorouracil; Herpes Zoster; Humans; Switzerland | 2009 |
Identification and location of label retaining cells in mouse liver.
Topics: Animals; Bromodeoxyuridine; Cyclin D3; Cyclin-Dependent Kinase 6; Female; Fluorouracil; Liver; Mice; Mice, Inbred ICR; Staining and Labeling; Stem Cells; Time Factors | 2010 |
Iba1(+)/NG2(+) macrophage-like cells expressing a variety of neuroprotective factors ameliorate ischemic damage of the brain.
Topics: Animals; Antigens; Bone Marrow Transplantation; Brain; Brain Ischemia; Bromodeoxyuridine; Calcium-Binding Proteins; Cell Proliferation; Cerebral Infarction; Fluorouracil; Glial Fibrillary Acidic Protein; Green Fluorescent Proteins; Humans; Immunohistochemistry; Infarction, Middle Cerebral Artery; Macrophages; Male; Microfilament Proteins; Neuroglia; Proteoglycans; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA | 2010 |
IGF-1 partially restores chemotherapy-induced reductions in neural cell proliferation in adult C57BL/6 mice.
Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Bromodeoxyuridine; Cell Proliferation; Cyclophosphamide; Dentate Gyrus; Doxorubicin; Fluorouracil; Humans; Insulin-Like Growth Factor I; Mice; Mice, Inbred C57BL; Neurogenesis; Neurons; Paclitaxel; Weight Loss | 2010 |
The human WRN and BLM RecQ helicases differentially regulate cell proliferation and survival after chemotherapeutic DNA damage.
Topics: Antineoplastic Agents; Bone Neoplasms; Bromodeoxyuridine; Camptothecin; Cell Growth Processes; Cell Line, Tumor; Cisplatin; DNA Damage; Exodeoxyribonucleases; Fibroblasts; Fluorouracil; Histones; Humans; Hydroxyurea; Osteosarcoma; RecQ Helicases; Werner Syndrome Helicase | 2010 |
Simple and rapid enzymatic method for the synthesis of single-strand oligonucleotides containing trifluorothymidine.
Topics: Autoradiography; Bromodeoxyuridine; Denaturing Gradient Gel Electrophoresis; DNA Damage; DNA Ligases; DNA Primers; DNA-Directed DNA Polymerase; Fluorouracil; Oligonucleotides; Thymine DNA Glycosylase; Trifluridine | 2010 |
Regeneration of dopaminergic neurons after 6-hydroxydopamine-induced lesion in planarian brain.
Topics: Analysis of Variance; Animals; Brain Injuries; Bromodeoxyuridine; Cell Cycle; Cell Movement; Cell Proliferation; Choline O-Acetyltransferase; Chromatography, High Pressure Liquid; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Fluorouracil; Glutamate Decarboxylase; Immunosuppressive Agents; Nerve Regeneration; Neurotoxins; Oxidopamine; Planarians; Pluripotent Stem Cells; Recovery of Function; Tyrosine 3-Monooxygenase; X-Rays | 2011 |
Fluoxetine counteracts the cognitive and cellular effects of 5-fluorouracil in the rat hippocampus by a mechanism of prevention rather than recovery.
Topics: Animals; Antidepressive Agents, Second-Generation; Antimetabolites, Antineoplastic; Body Weight; Bromodeoxyuridine; Cell Proliferation; Cognition Disorders; Dentate Gyrus; Drinking; Fluorouracil; Fluoxetine; Hippocampus; Ki-67 Antigen; Male; Memory; Rats; Space Perception; Time Factors; Weight Gain | 2012 |
The lectin of Dolichos biflorus agglutinin recognises glycan epitopes on the surface of a subset of cardiac progenitor cells.
Topics: Animals; Bromodeoxyuridine; Cell Proliferation; Clone Cells; Epitopes; Fluorouracil; Mice; Mice, Inbred ICR; Myocardium; Plant Lectins; Polysaccharides; Proto-Oncogene Proteins c-kit; Staining and Labeling; Stem Cells | 2013 |
Attenuation of nucleoside and anti-cancer nucleoside analog drug uptake in prostate cancer cells by Cimicifuga racemosa extract BNO-1055.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Bromodeoxyuridine; Cell Line; Cell Proliferation; Cimicifuga; Deoxycytidine; Dose-Response Relationship, Drug; Equilibrative Nucleoside Transport Proteins; Fluorouracil; Gemcitabine; Humans; Male; Nucleosides; Phytotherapy; Plant Extracts; Prostate; Prostatic Neoplasms; RNA, Small Interfering; Saponins; Thymidine; Vidarabine | 2013 |
β-l-1-[5-(E-2-bromovinyl)-2-(hydroxymethyl)-1,3-(dioxolan-4-yl)] uracil (l-BHDU) prevents varicella-zoster virus replication in a SCID-Hu mouse model and does not interfere with 5-fluorouracil catabolism.
Topics: Acyclovir; Animals; Antiviral Agents; Bromodeoxyuridine; Cell Line; Chickenpox; Dioxolanes; Drug Therapy, Combination; Fluorouracil; Foscarnet; Herpes Zoster; Herpesvirus 3, Human; Humans; Mice; Mice, Inbred BALB C; Mice, SCID; Nucleosides; Organ Culture Techniques; Skin; Uracil; Virus Replication | 2014 |
Laser-induced drug release for local tumor control--a proof of concept.
Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; beta-Cyclodextrins; Bromodeoxyuridine; Cell Line, Tumor; Dimerization; Drug Delivery Systems; Fibroblasts; Flow Cytometry; Fluorouracil; Hydrophobic and Hydrophilic Interactions; Lasers; Palliative Care; Pancreatic Neoplasms; Solubility; Stents | 2014 |
[Lethal interaction between 5-fluorouracil and brivudine].
Topics: Aged; Antimetabolites, Antineoplastic; Antiviral Agents; Bromodeoxyuridine; Diagnostic Errors; Drug Interactions; Fatal Outcome; Fluorouracil; Herpes Zoster; Humans; Male | 2018 |