bromodeoxyuridine has been researched along with deoxyuridine in 165 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 89 (53.94) | 18.7374 |
| 1990's | 18 (10.91) | 18.2507 |
| 2000's | 15 (9.09) | 29.6817 |
| 2010's | 38 (23.03) | 24.3611 |
| 2020's | 5 (3.03) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, MS; Prusoff, WH; Schinazi, RF | 1 |
| Knaus, EE; Mercer, JR; Wiebe, LI; Xu, LH | 1 |
| Meyer, RB; Nakayama, C; Saneyoshi, M; Santi, DV; Ueda, T; Wataya, Y | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Dundaroff, S; Falke, D; Just, I | 1 |
| Bilello, JA; Koch, G; Kühne, J; Warnecke, G | 1 |
| Poirier, LA; Shimkin, MB; Stoner, GD | 1 |
| Mathews, CK | 1 |
| Bryan, AM; Lau, K; Olafsson, PG | 1 |
| Schluter, DN; Wigler, PW | 1 |
| Baker, PN; Bradshaw, TK; Burke, DC; Morser, J | 1 |
| Parsons, PG; Smellie, SG | 1 |
| Bernhard, WA; Haindl, E; Hüttermann, J; Schmidt, G | 1 |
| Halpern, A; Stöcklin, G | 1 |
| Balint, RF; Gauri, KK; Silagi, S | 1 |
| Gati, WP; Knaus, EE; Kumar, P; Singh, S; Tandon, M; Tempest, ML; Wiebe, LI; Xu, L | 1 |
| Claes, P; De Clercq, E; Herdewijn, P; Pannecouque, C; Snoeck, R; Wigerinck, P | 1 |
| Menon, VV; Rachel, AJ; Sharma, T | 1 |
| Stobetskiĭ, VI | 2 |
| Balzarini, J; Baumgartner, H; Bodenteich, M; De Clercq, E; Griengl, H | 2 |
| Aduma, PJ; De Clercq, E; Gupta, SV | 1 |
| De Clercq, E; Griengl, H; Hayden, W; Penn, G; Rosenwirth, B | 1 |
| Balzarini, J; De Clercq, E; Herdewijn, P; Vanderhaeghe, H | 1 |
| Gentry, GA; Veerisetty, V | 3 |
| De Clercq, E; Desgranges, C; Herdewijn, P; Jones, AS; McLean, MJ; Sim, IS; Walker, RT | 1 |
| Belloc, I; Bricaud, H; De Clercq, E; Desgranges, C; Drouillet, F; Razaka, G | 1 |
| De Clercq, E; Griengl, H; Rosenwirth, B; Schwarz, W; Streicher, W; Wanek, E | 1 |
| Freeman, DJ; Spruance, SL | 1 |
| Dunkel, EC; Geary, PA; Imperia, PS; Lass, JH; Lazarus, HM; Pavan-Langston, D | 1 |
| Mironova, LL; Stobetskiĭ, VI | 1 |
| Cortés, F; Morgan, WF; Wolff, S | 1 |
| Hume, WJ; Saffhill, R | 1 |
| Bernaerts, R; Breemersch, M; De Clercq, E; Dieltiens, M; Maudgal, PC; Van Eeckhoutte, L | 1 |
| Ockey, CH; Saffhill, R | 1 |
| Bachmayer, H; Bodenteich, M; Ghazzouli, I; Griengl, H; Hayden, W; Rosenwirth, B; Streicher, W; Stütz, P; Wanek, E | 1 |
| De Vrye, CE; Fahmy, MJ; Fahmy, OG | 1 |
| Bresnick, E; Williams, SS | 1 |
| Rahman, A; Wilson, HR | 1 |
| Chang, PK; Prusoff, WH; Voytek, P | 1 |
| Beck, A; Tan, YL | 1 |
| Painter, RB | 1 |
| Ohyama, K | 1 |
| Bryan, AM; Olafsson, PG | 1 |
| Dubbs, DR; Frearson, PM; Kit, S; Melnick, JL | 1 |
| Bader, JP | 1 |
| Clarkson, BD; Duschinsky, R; Keller, O; Krakoff, IH; La Sala, E; Van Dyk, JJ | 1 |
| Herrmann, EC | 1 |
| Aaronson, SA | 1 |
| Fujimura, RK | 2 |
| Hartley, JW; Lowy, DR; Rowe, WP; Teich, N | 1 |
| Braek, OG; Smith-Kielland, I | 1 |
| Magdon, E | 1 |
| Bors, W; Kourim, P; Schulte-Frohlinde, D | 2 |
| Kaplan, LA; Kit, S; Leung, WC; Trkula, D | 1 |
| Hayatsu, H; Negishi, K; Wataya, Y | 1 |
| Jasińska, JK; Steffen, JA; Swierkowska, KM | 1 |
| Walker, JL; Webb, SJ | 1 |
| Beacham, IR; Pritchard, RH | 1 |
| Danzig, M; Shapiro, R | 1 |
| Schweiger, K; Streffer, C | 1 |
| Scocca, JJ | 1 |
| Coleman, AW; Coleman, JR; Hartline, EJ | 1 |
| Kang, S; Shapiro, R | 1 |
| Suit, HD | 1 |
| Hofer, B; Köster, H | 1 |
| Gati, WP; Knaus, EE; Wiebe, LI | 1 |
| Cheng, YC; De Clercq, E; Dutschman, G; Jones, AS; Rahim, SG; Verhelst, G; Walker, RT | 1 |
| de Clercq, E | 1 |
| Bergstrom, DE; de Clercq, E; Descamps, J; Verhelst, G | 1 |
| Allaudeen, HS; Chen, MS; De Clercq, E; Lee, JJ; Prusoff, WH | 1 |
| Cheng, YC; Dutschman, GE; Grill, SP; Schinazi, RF; Tan, RS | 1 |
| Cheng, YC; De Clercq, E; Dutschman, GE; Zou, FC | 1 |
| Mullenders, LH; Natarajan, AT; van Zeeland, AA; Zwanenburg, TS | 2 |
| DuFrain, RJ | 1 |
| Heartlein, MW; O'Neill, JP; Preston, RJ | 3 |
| Balzarini, J; Bricaud, H; De Clercq, E; Desgranges, C; Rabaud, M; Razaka, G | 1 |
| DuFrain, RJ; Jennings, CJ; Linkous, S; Lowe, KW; McFee, AF | 1 |
| Balzarini, J; De Clercq, E; Hunston, RN; Jones, AS; McGuigan, C; Walker, RT | 1 |
| O'Neill, JP | 1 |
| Allaudeen, HS; De Clercq, E; Descamps, J; Jones, AS; Kozarich, JW; Walker, RT | 1 |
| Heartlein, MW; O'Neill, JP; Pal, BC; Preston, RJ | 1 |
| DuFrain, RJ; Garrand, TJ | 1 |
| De Clercq, E; Jones, AS; Rahim, SG; Serafinowski, P; Walker, RT | 1 |
| Cheraghali, AM; Knaus, EE; Kumar, R; Wiebe, LI | 1 |
| Creuven, I; Dory, M; Durant, F; Evrard, C; Evrard, G; Herdewijn, P; Olivier, A; van Aerschot, A; Wigerinck, P | 1 |
| Docherty, JJ; Wilber, BA | 1 |
| Clairmont, C; Hellstrand, K; Hirschberg, C; Olofsson, S; Shugar, D; Sjöblom, I | 1 |
| De Clercq, E; Huyghe, P; Maudgal, PC | 1 |
| Chebotarev, AN; Kuleshov, NP; Samochatova, EV; Stobetskiĭ, VI | 1 |
| Freytag, SO; Kim, JH; Kim, SH; Rogulski, KR | 1 |
| Furusawa, Y; Hieda, K; Kobayashi, K; Maezawa, H; Takakura, K | 1 |
| Barendsen, GW; Franken, NA; Kipp, JB; Van Bree, CV | 1 |
| Bakker, PJ; Barendsen, GW; Franken, NA; Kipp, JB; Klomp-Tukker, LJ; Van Bree, C | 1 |
| Focher, F; Priori, G; Spadari, S; Tondelli, L; Verri, A | 1 |
| Ansorge, W; Cremer, T; Fischer, R; Saffrich, R; Stelzer, EH; Trendelenburg, MF; Zink, D | 1 |
| Chebotarev, AN; Kuleshov, NP; Kuzina, NIu; Stobetskiĭ, VI | 1 |
| HOLTZER, H; NAMEROFF, M; OKAZAKI, K; STOCKDALE, F | 1 |
| ARBER, W; BROWN, A | 1 |
| DUBBS, DR; KIT, S | 1 |
| Barone, TA; Maslov, AY; Plunkett, RJ; Pruitt, SC | 1 |
| Wagenknecht, HA; Wagner, C | 1 |
| Ding, X; Ma, N; Nagahama, M; Semba, R; Yamada, K | 1 |
| Engelbrecher, A; Häuser, R; Titz, B; Uetz, P | 1 |
| Conboy, MJ; Karasov, AO; Rando, TA | 1 |
| Kimoto, M; Kishino, M; Ogawa, Y; Toyosawa, S; Yura, Y | 1 |
| Biggiogera, M; Fakan, S; Solimando, L; Vecchio, L | 1 |
| Gilbert, DM; Yokochi, T | 1 |
| Cappella, P; Gasparri, F; Moll, J; Pulici, M | 2 |
| Agnew, BJ; Bradford, J; Buck, SB; Clarke, ST; Gee, KR; Salic, A | 1 |
| Barnard, DL; Humphreys, DE; Hurst, BL; Smee, DF | 1 |
| Bonaguidi, MA; Czeisler, C; Falciglia, G; Gobeske, KT; Kessler, JA; McGuire, T; Peng, CY | 1 |
| Bradford, JA; Brockhoff, G; Clarke, ST; Diermeier-Daucher, S; Hill, D; Vollmann-Zwerenz, A | 1 |
| Backus, C; Edwards, JL; Feldman, EL; Haines, KM; Lentz, SI; McLean, LL | 1 |
| Griffin, EA; Holtzman, DM; Jones, LA; Lim, MM; Mach, RH; Mintun, MA; Pan, F; Sheline, YI; Zeng, C | 1 |
| Clivio, P; Gourdain, S; Harakat, D; Petermann, C | 1 |
| Brockhoff, G; Diermeier-Daucher, S | 1 |
| Lu, QB; Wang, CR | 1 |
| Bradford, JA; Clarke, ST | 1 |
| Imai, M; Kobayashi, K; Mochizuki, H; Mori, K; Murata, K; Nakanishi, S; Nihira, T; Pastan, I; Watanabe, D; Yamada, S; Yamaguchi, M | 1 |
| Cavanagh, BL; Meedeniya, AC; Norazit, A; Walker, T | 1 |
| Bennett, SA; Desroches, R; Pettit, AS | 1 |
| Luedtke, NW; Neef, AB | 1 |
| Fowler, DH; Lavie, A; Medin, JA; Neschadim, A; Sato, T; Wang, JC | 1 |
| Albers, SV; Bell, SD; Duggin, IG; Gristwood, T; Wagner, M | 1 |
| Chapman, K; Komitova, M; Ment, LR; Mitchell, P; Salmaso, N; Schwartz, ML; Silbereis, J; Vaccarino, FM | 1 |
| Brimble, MA; Cox, BC; Liu, Z; Mellado Lagarde, MM; Owen, T; Steigelman, KA; Valentine, MB; Walters, BJ; Yu, Y; Zhang, L; Zuo, J | 1 |
| Li, J; Lin, G; Sun, Y; Wang, L; Xie, J; Zhang, K; Zhang, R | 1 |
| Blanding, WM; Booth, BW; Feltracco, JA; Park, JP; Raafat, A | 1 |
| Koberna, K; Liboska, R; Ligasová, A; Rosenberg, I; Strunin, D | 1 |
| Andersen, DC; Christensen, ML; Jensen, CH; Sheikh, SP; Skovrind, I | 1 |
| Anda, S; Boye, E; Grallert, B | 1 |
| Bery, A; Boussin, FD; Desmaze, C; Etienne, O; Roque, T | 1 |
| Oosterwijk, E; Sun, W; Wilhelmina Aalders, T | 1 |
| Asano, M; Nishimura, N; Sonoyama, K; Tsuruta, T; Yamamoto, T | 1 |
| Cappella, P; Gasparri, F; Pulici, M | 1 |
| Hünig, T; Kitazawa, Y; Matsuno, K; Sawanobori, Y; Ueta, H | 1 |
| Flomerfelt, FA; Gress, RE | 1 |
| Coulter, J; DeWeese, TL; Greenberg, MM; Hou, D; Rudra, A; Zhang, Y; Zhou, H | 1 |
| Alwaal, A; Banie, L; Jia, X; Lin, CS; Lin, G; Lue, TF; Villalta, J; Wang, G; Wang, J; Zhang, X | 1 |
| Adam, T; Friedecký, D; Koberna, K; Liboska, R; Ligasová, A; Mičová, K; Oždian, T; Rosenberg, I | 1 |
| Smith, PJ | 1 |
| Cella Zanacchi, F; Cremer, C; Darzynkiewicz, Z; Diaspro, A; Dobrucki, JW; Drukała, J; Pennacchietti, F; Pierzyńska-Mach, A; Szczurek, A | 1 |
| Chen, Z; Xu, H | 1 |
| Ball, GF; Balthazart, J; Cornil, CA; Shevchouk, OT | 1 |
| Armelin, HA; da Silva, MS; Elias, MC; Muñoz, PAM | 1 |
| Bedogni, F; Cobolli Gigli, C; De Simone, M; Landsberger, N; Pagani, M; Pozzi, D; Rossi, RL; Scaramuzza, L | 1 |
| Beltz, BS; Brenneis, G; Scholtz, G | 1 |
| Atsak, P; Dranovsky, A; Kirshenbaum, GS; Krish, VS; Lass, TJ; Leonardo, ED; Lieberman, SR; Youssef, M | 1 |
| Báječný, M; Nečas, E; Páral, P; Savvulidi, F | 1 |
| Antonov, SA; Grivennikov, IA; Kobylansky, AG; Novosadova, EV; Tarantul, VZ | 1 |
| Allum, AJ; Froning, CE; Haskins, AH; Haskins, JS; Kato, TA; Maeda, J; Su, C; Walsh, KD | 1 |
| Belousov, VV; Enikolopov, GN; Maltsev, DI; Mellanson, KA; Podgorny, OV | 1 |
| Baranov, MV; Bianchi, F; de Wit, AS; Maassen, S; Stempels, FC; Swierstra, MS; van den Bogaart, G | 1 |
| Cross, SJ; George, SJ; Johnson, JL; Reolizo, LM; Somos, A; Wadey, KS | 1 |
6 review(s) available for bromodeoxyuridine and deoxyuridine
| Article | Year |
|---|---|
Radiation sensitizers.
Topics: Animals; Antineoplastic Agents; Bromodeoxycytidine; Bromodeoxyuridine; Carcinoma; Deoxyuridine; Dogs; Dose-Response Relationship, Radiation; Floxuridine; Humans; Hypoxia; Idoxuridine; Lung Neoplasms; Methotrexate; Metronidazole; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents; Research; Sarcoma, Experimental; Skin | 1976 |
Chemical and biological consequences of beta-decay. Part 1.
Topics: Bromodeoxyuridine; Carbon Radioisotopes; Cytosine; Deoxyuridine; Free Radicals; Idoxuridine; Iodine Radioisotopes; Isotope Labeling; Phenols; Phosphorus Radioisotopes; Radioactive Tracers; Radioactivity; Radioisotopes; Succinates; Sulfur Radioisotopes; Thymidine; Tritium; Tyrosine; Uracil | 1977 |
The action of ultraviolet light on mammalian cells.
Topics: Animals; Bromodeoxyuridine; Cell Division; Cells, Cultured; Chlorides; Chromosome Aberrations; Cricetinae; Deoxyuridine; DNA Repair; DNA Replication; Floxuridine; Humans; Iodides; Metabolism; Mice; Microchemistry; Mitosis; Protein Biosynthesis; Radiation Effects; RNA; Swine; Time Factors; Tritium; Ultraviolet Rays | 1970 |
Some implications of the activation of murine leukemia virus by halogenated pyrimidines.
Topics: Animals; Antigens, Viral; Bromodeoxyuridine; Clone Cells; Culture Techniques; Cytosine Nucleotides; Deoxyuridine; DNA, Viral; Embryo, Mammalian; Genetic Code; Iodine; Leukemia Virus, Murine; Light; Mice; Mice, Inbred Strains; Rats; Virus Replication | 1972 |
Nucleoside analogues as antiviral agents.
Topics: Acyclovir; Adenine; Animals; Antiviral Agents; Arabinonucleosides; Bromodeoxyuridine; Chemical Phenomena; Chemistry; Cytarabine; Deoxyuridine; Guanine; Herpesviridae Infections; Humans; Idoxuridine; Nucleosides; Ribavirin; Thymidine; Virus Diseases; Viruses | 1981 |
Thymidine analogues for tracking DNA synthesis.
Topics: Animals; Bromodeoxyuridine; Cell Proliferation; Cells, Cultured; Click Chemistry; Deoxyuridine; DNA; Fluorescent Dyes; Humans; Staining and Labeling; Stem Cell Niche; Thymidine | 2011 |
159 other study(ies) available for bromodeoxyuridine and deoxyuridine
| Article | Year |
|---|---|
Synthesis and biological activities of some uronic acids, uronates, uronamides, and urononitriles of pyrimidine nucleosides.
Topics: Animals; Cell Division; Cells, Cultured; Chick Embryo; Pyrimidine Nucleosides; Sarcoma 180; Simplexvirus; Streptococcus; Structure-Activity Relationship; Substrate Specificity; Thymidine Kinase; Thymidylate Synthase; Uronic Acids; Virus Replication | 1978 |
Synthesis and tumor uptake of 5-82Br- and 5-131I-labeled 5-halo-1-(2-fluoro-2-deoxy-beta-D-ribofuranosyl)uracils.
Topics: Animals; Biological Transport; Bromine Radioisotopes; Chemical Phenomena; Chemistry; DNA; Female; Floxuridine; Iodine Radioisotopes; Isotope Labeling; Lung Neoplasms; Mice; Molecular Structure; Structure-Activity Relationship; Tissue Distribution | 1989 |
Thymidine phosphorylase. Substrate specificity for 5-substituted 2'-deoxyuridines.
Topics: Animals; Deoxyuridine; Horses; In Vitro Techniques; Models, Biological; Pentosyltransferases; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Substrate Specificity; Thymidine Phosphorylase | 1980 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Biochemical classification of herpes simplex virus types 1 and 2, and of intermediate strains on the basis of different susceptibilities of thymidine kinase to thymidine analogues.
Topics: Bromodeoxyuridine; Cell-Free System; Culture Techniques; Deoxyuridine; Mercaptoethanol; Simplexvirus; Thymidine; Thymidine Kinase; Thymine Nucleotides | 1976 |
Effect of base analogs upon the induction of differentation in Friend erythroleukemia cells.
Topics: Animals; Bromodeoxyuridine; Cell Differentiation; Cell Division; Cell Line; Cell Transformation, Viral; Deoxyuridine; Friend murine leukemia virus; Leukemia, Erythroblastic, Acute; Mice; Protein Biosynthesis; Vidarabine Phosphate | 1979 |
Bioassay of alkyl halides and nucleotide base analogs by pulmonary tumor response in strain A mice.
Topics: Adenoma; Alkanes; Animals; Biological Assay; Bromodeoxyuridine; Carcinogens; Deoxyuridine; Female; Floxuridine; Halogens; Idoxuridine; Lung Neoplasms; Male; Mice; Mice, Inbred A; Neoplasms, Experimental | 1975 |
Effects of thymidine analogs upon growth control in cultured hormone-dependent ray ovary cells.
Topics: Animals; Bromodeoxyuridine; Cell Differentiation; Cell Division; Cell Line; Cell Survival; Culture Media; Cytarabine; Deoxyuridine; DNA; Female; Floxuridine; Hormones; Hydroxyurea; Idoxuridine; Kinetics; Ovarian Neoplasms; Rats; Thymidine | 1975 |
A differential scanning calorimetric-thin-layer chromatographic study of 5-halo-2'-deoxynucleosides.
Topics: Bromodeoxyuridine; Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Deoxyuridine; Floxuridine; Idoxuridine; Uracil | 1976 |
Inhibition of membrane transport of 5-fluoro[6-3H]deoxyuridine into L5178Y mouse leukemia cells.
Topics: Animals; Biological Transport; Bromodeoxyuridine; Cell Line; Cell Membrane; Deoxyuridine; Floxuridine; Leukemia, Experimental; Thymidine Kinase; Tritium | 1976 |
The effect of 5-bromodeoxyuridine on interferon production in human cells.
Topics: Bromodeoxyuridine; Cell Division; Cell Line; Deoxycytidine; Deoxyuridine; DNA; Floxuridine; Humans; Idoxuridine; Interferons; Thymidine | 1979 |
Effects of thymidine analogues on murine and human cells.
Topics: Animals; Bromodeoxyuridine; Cell Count; Cell Line; Deoxyuridine; Fibroblasts; Floxuridine; Humans; Idoxuridine; Mice; Neoplasms; Neoplasms, Experimental; Thymidine | 1979 |
A C5'-centred deoxyribose radical in single crystals of 5-chloro-and 5-bromodeoxyuridine X-irradiated at low temperatures.
Topics: Bromodeoxyuridine; Deoxyribose; Deoxyuridine; Electron Spin Resonance Spectroscopy; Free Radicals; Temperature; X-Rays | 1977 |
Comparative effects on growth and tumorigenicity of mouse melanoma cells by thymidine and its analogs, 5-ethyl- and 5-bromodeoxyuridine.
Topics: Animals; Bromodeoxyuridine; Cell Division; Cells, Cultured; Deoxyuridine; DNA, Neoplasm; Kinetics; Melanins; Melanoma; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Thymidine; Transplantation, Homologous | 1977 |
Synthesis and biological activity of 5-(2,2-difluorocyclopropyl)-2'-deoxyuridine deoxyuridine diastereomers.
Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Carrier Proteins; Cell Survival; Cytopathogenic Effect, Viral; Deoxyuridine; Erythrocyte Membrane; Membrane Proteins; Mice; Nucleoside Transport Proteins; Simplexvirus; Stereoisomerism; Viral Plaque Assay | 1992 |
5-(5-Bromothien-2-yl)-2'-deoxyuridine and 5-(5-chlorothien-2-yl)-2'-deoxyuridine are equipotent to (E)-5-(2-bromovinyl)-2'-deoxyuridine in the inhibition of herpes simplex virus type I replication.
Topics: Antiviral Agents; Bromodeoxyuridine; Chemical Phenomena; Chemistry; Deoxyuridine; Herpesvirus 3, Human; Molecular Structure; Simplexvirus; Structure-Activity Relationship; Thiophenes; Virus Replication | 1991 |
Harlequin banding and localisation of sister-chromatid exchanges.
Topics: Animals; Bromodeoxyuridine; Chromosome Banding; Deer; Deoxyuridine; In Vitro Techniques; Metaphase; Mitomycin; Sister Chromatid Exchange | 1991 |
[Telomeric chromosome fusion in cells with micronuclei under the combined action of hyperthermia and hypothermia and halogenated analogs of thymidine].
Topics: Animals; Bromodeoxyuridine; Cells, Cultured; Chromosome Aberrations; Cricetinae; Cricetulus; Deoxyuridine; Idoxuridine; Micronuclei, Chromosome-Defective; Telomere; Temperature; Thymidine | 1991 |
Carbocyclic 5-iodo-2'-deoxyuridine (C-IDU) and carbocyclic (E)-5-(2-bromovinyl)-2'-deoxyuridine (C-BVDU) as unique examples of chiral molecules where the two enantiomeric forms are biologically active: interaction of the (+)- and (-)-enantiomers of C-IDU
Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Cell Division; Cyclopentanes; Deoxyuridine; Kinetics; Mice; Phosphorylation; Simplexvirus; Stereoisomerism; Structure-Activity Relationship; Thymidine Kinase; Tumor Cells, Cultured | 1990 |
Antiherpes virus activity and effect on deoxyribonucleoside triphosphate pools of (E)-5-(2-bromovinyl)-2'-deoxycytidine in combination with deaminase inhibitors.
Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Cell Line; Cytidine Triphosphate; Deoxyuridine; DNA, Viral; Dose-Response Relationship, Drug; Drug Interactions; Humans; Purine Nucleotides; Pyrimidine Nucleotides; Simplexvirus; Tetrahydrouridine; Thymine Nucleotides; Virus Replication | 1990 |
Synthesis and antiviral activity of the enantiomeric forms of carba-5-iodo-2'-deoxyuridine and carba-(E)-5-(2-bromovinyl)-2'-deoxyuridine.
Topics: Antiviral Agents; Bromodeoxyuridine; Chemical Phenomena; Chemistry; Cyclopentanes; Deoxyuridine; Microbial Sensitivity Tests; Simplexvirus; Stereoisomerism | 1989 |
Phosphonoformate and phosphonoacetate derivatives of 5-substituted 2'-deoxyuridines: synthesis and antiviral activity.
Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Cell Line; Chemical Phenomena; Chemistry; Deoxyuridine; Foscarnet; Herpes Simplex; Mice; Organophosphorus Compounds; Pharmaceutical Preparations; Phosphonoacetic Acid; Prodrugs; Rabbits; Simplexvirus; Thymidine; Vero Cells | 1988 |
Synthesis and antiviral activity of the carbocyclic analogues of (E)-5-(2-halovinyl)-2'-deoxyuridines and (E)-5-(2-halovinyl)-2'-deoxycytidines.
Topics: Animals; Antineoplastic Agents; Antiviral Agents; Bromodeoxyuridine; Cell Division; Cell Line; Cyclopentanes; Cytopathogenic Effect, Viral; Deoxycytidine; Deoxyuridine; Herpes Simplex; Humans; Mice; Mice, Hairless; Rabbits; Rats; Simplexvirus; Vaccinia virus; Vesicular stomatitis Indiana virus; Virus Cultivation | 1985 |
HSV1-specific thymidylate kinase activity in infected cells.
Topics: Acyclovir; Animals; Bromodeoxyuridine; Cells, Cultured; Cricetinae; Deoxyuridine; Drug Resistance, Microbial; Herpes Simplex; Kinetics; Mice; Nucleoside-Phosphate Kinase; Phosphonoacetic Acid; Phosphorylation; Phosphotransferases; Substrate Specificity | 1985 |
Synthesis and antiviral activity of (E)-5-(2-bromovinyl)uracil and (E)-5-(2-bromovinyl)uridine.
Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Bromouracil; Deoxyuridine; Herpes Simplex; Mice; Mice, Inbred BALB C; Rabbits; Simplexvirus; Thymine; Uridine; Virus Replication | 1986 |
Deoxyribosyl exchange reactions leading to the in vivo generation and regeneration of the antiviral agents (E)-5-(2-bromovinyl)-2'-deoxyuridine, 5-ethyl-2'-deoxyuridine and 5-(2-chloroethyl)-2'-deoxyuridine.
Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Bromouracil; Deoxyuridine; Half-Life; Humans; Male; Rabbits; Rats; Rats, Inbred Strains; Simplexvirus; Uracil | 1986 |
2'-Fluorinated arabinonucleosides of 5-(2-haloalkyl)uracil: synthesis and antiviral activity.
Topics: Antiviral Agents; Bromodeoxyuridine; Deoxyuridine; Floxuridine; Simplexvirus; Structure-Activity Relationship | 1987 |
Efficacy of topical treatment for herpes simplex virus infections: predictions from an index of drug characteristics in vitro.
Topics: Acyclovir; Administration, Topical; Animals; Antiviral Agents; Bromodeoxyuridine; Deoxyuridine; Diffusion; Female; Guinea Pigs; Herpes Simplex; Idoxuridine; Pharmaceutical Vehicles; Skin Diseases; Trifluridine; Vidarabine | 1986 |
An in vitro study of ophthalmic antiviral agent toxicity on rabbit corneal epithelium.
Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Cell Survival; Cornea; Deoxyuridine; Epithelium; Idoxuridine; In Vitro Techniques; Rabbits; Thymidine; Trifluridine | 1988 |
[5-Chlorodeoxyuridine, more effectively than 5-bromodeoxyuridine, induces the formation of specific dicentric chromosomes in cells with micronuclei].
Topics: Animals; Bromodeoxyuridine; Cell Line; Cells, Cultured; Chromosome Aberrations; Cricetinae; Cricetulus; Demecolcine; Deoxyuridine; Micronucleus Tests; Molecular Weight | 1988 |
Effect of exogenous thymidine on sister-chromatid exchange frequency in Chinese hamster ovary cells with bromodeoxyuridine- and chlorodeoxyuridine-substituted chromosomes.
Topics: Animals; Bromodeoxyuridine; Cell Cycle; Cell Line; Cricetinae; Cricetulus; Deoxyuridine; Sister Chromatid Exchange; Thymidine | 1987 |
The degradation of 5-iododeoxyuridine and 5-bromodeoxyuridine by serum from different sources and its consequences for the use of the compounds for incorporation into DNA.
Topics: Animals; Bromodeoxyuridine; Bromouracil; Chromatography, High Pressure Liquid; Deoxyuridine; DNA; Horses; Idoxuridine; Male; Mice; Rabbits; Species Specificity; Thyroid Gland; Uracil | 1986 |
Ocular penetration and efficacy of chloroethyldeoxyuridine against herpetic keratouveitis.
Topics: Animals; Anterior Chamber; Antiviral Agents; Bromodeoxyuridine; Deoxyuridine; Iritis; Keratitis, Dendritic; Ophthalmic Solutions; Rabbits | 1986 |
Strand breaks arising from the repair of the 5-bromodeoxyuridine-substituted template and methyl methanesulphonate-induced lesions can explain the formation of sister chromatid exchanges.
Topics: Animals; Benzamides; Bromodeoxyuridine; Cell Line; Cricetinae; Cricetulus; Deoxyuridine; DNA; DNA Repair; Female; Kinetics; Methyl Methanesulfonate; Ovary; Sister Chromatid Exchange; Templates, Genetic | 1985 |
5-(Haloalkyl)-2'-deoxyuridines: a novel type of potent antiviral nucleoside analogue.
Topics: Animals; Bromodeoxyuridine; Chemical Phenomena; Chemistry; Deoxyuridine; Dose-Response Relationship, Drug; Halogens; Herpes Simplex; Mice; Rats | 1985 |
The mutagenic properties of the nucleosides of pyrimidine analogues in Drosophila melanogaster.
Topics: Animals; Antimetabolites; Bromodeoxyuridine; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Deoxyuridine; Drosophila; Floxuridine; Mutagens; Mutation; Nucleosides | 1966 |
Effects of 5-trifluoromethyldeoxyuridine upon deoxythymidine kinase.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Bromodeoxyuridine; Carbon Isotopes; Culture Media; Deoxyuridine; Floxuridine; Kinetics; Liver; Male; Nucleotides; Oxidative Phosphorylation; Rats; Thymidine Kinase | 1967 |
Molecular conformation of deoxyuridine.
Topics: Base Sequence; Bromodeoxyuridine; Chemical Phenomena; Chemistry; Deoxyuridine; Floxuridine; Idoxuridine; Models, Structural | 1971 |
Kinetic and photochemical studies of 3-N-methyl-5-iodo-2-'-deoxyuridine. Sensitization of ultraviolet inactivation of thymidine kinase by 3-N-methyl-5-iodo-2'-deoxyuridine and other halogenated analogs of thymidine.
Topics: Adenosine Triphosphate; Bromodeoxyuridine; Carbon Isotopes; Cytosine Nucleotides; Deoxyribonucleotides; Deoxyuridine; Escherichia coli; Floxuridine; Idoxuridine; Iodine; Kinetics; Magnesium; Methylation; Photochemistry; Photolysis; Radiation Effects; Spectrophotometry; Stimulation, Chemical; Thymidine; Thymidine Kinase; Thymine Nucleotides; Ultraviolet Rays | 1972 |
Complex formation of uracil, 2'-deoxyuridine and their 5-halogenated derivatives.
Topics: Bromodeoxyuridine; Bromouracil; Chemical Phenomena; Chemistry; Copper; Deoxyuridine; Drug Stability; Floxuridine; Fluorouracil; Idoxuridine; Mathematics; Nickel; Potentiometry; Silver; Uracil | 1973 |
Properties of 5-bromodeoxyuridine-resistant lines of higher plant cells in liquid culture.
Topics: Aminopterin; Biological Transport; Bromodeoxyuridine; Carbon Radioisotopes; Cell Division; Cell Line; Centrifugation, Density Gradient; Culture Media; Deoxyuridine; DNA; Drug Resistance; Floxuridine; Glycine; Glycine max; Hypoxanthines; Nitrosoguanidines; Plants; Protoplasts; Thymidine; Thymidine Kinase; Time Factors; Tritium | 1974 |
The influence of 5-halo substituents on the thermal depyrimidination of the glycosidic bond in 2'-deoxyuridines.
Topics: Bromodeoxyuridine; Calorimetry; Deoxyuridine; Floxuridine; Guanosine; Iodine; Molecular Conformation; Temperature; Thermodynamics; Thymidine; Thymine; Uracil | 1974 |
Enzyme induction in SV40-infected green monkey kidney cultures.
Topics: Adenine Nucleotides; Autoradiography; Bromodeoxyuridine; Cycloheximide; Cytarabine; Deoxyuridine; DNA; DNA, Viral; Enzymes; In Vitro Techniques; Intestinal Diseases; Kinetics; Ligases; Protein Biosynthesis; Simian virus 40; Thymidine Kinase; Tritium | 1966 |
Metabolic requirements for infection by Rous sarcoma virus. II. The participation of cellular DNA.
Topics: Avian Sarcoma Viruses; Bromodeoxyuridine; Culture Techniques; Deoxyuridine; DNA; RNA | 1966 |
Clinical evaluation of 5-bromo-5-fluoro-6-methoxy-dihydro-2'-deoxyuridine.
Topics: Adenocarcinoma; Adult; Aged; Animals; Bromodeoxyuridine; Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Squamous Cell; Colonic Neoplasms; Deoxyuridine; Dogs; Female; Floxuridine; Gallbladder Neoplasms; Gastrointestinal Neoplasms; Humans; Ileocecal Valve; Intestinal Neoplasms; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Pancreatic Neoplasms; Rectal Neoplasms; Sarcoma; Stomach Neoplasms | 1967 |
Sensitivity of herpes simplex virus, vaccinia virus, and adenoviruses to deoxyribonucleic acid inhibitors and thiosemicarbazones in a plaque suppression test.
Topics: Adenoviridae; Antiviral Agents; Bromodeoxyuridine; Cytarabine; Cytopathogenic Effect, Viral; Deoxyuridine; Floxuridine; HeLa Cells; Idoxuridine; Simplexvirus; Thiosemicarbazones; Vaccinia virus | 1968 |
Chemical induction of focus-forming virus from nonproducer cells transformed by murine sarcoma virus.
Topics: Amines; Animals; Antigens, Viral; Bromodeoxyuridine; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Cytosine Nucleotides; Deoxyuridine; Fluorouracil; Gammaretrovirus; Helper Viruses; Iodine; Mercaptopurine; Mice; Moloney murine leukemia virus; Rats; Rauscher Virus; Time Factors; Virus Replication | 1971 |
Biochemical analysis of the naturally repaired sections of bacteriophage T5 deoxyribonucleic acid. 3. Nucleotide analysis of deoxyribonucleic acid synthesized under nonpermissive conditions.
Topics: Bromodeoxyuridine; Centrifugation, Density Gradient; Chromatography; Chromatography, Gel; Coliphages; Deoxyribonucleotides; Deoxyuridine; Deuterium; DNA Nucleotidyltransferases; DNA Repair; DNA, Viral; Electrophoresis; Genetics, Microbial; Mutation; Nitrogen Isotopes; Nucleic Acid Hybridization; Phosphates; Phosphoric Monoester Hydrolases; Phosphorus Isotopes; Spleen; Tritium | 1971 |
The demonstration of protein synthesis-dependent repair replication in Escherichia coli after treatment with the mono-alkylating agent ethyl methane sulphonate.
Topics: Bacterial Proteins; Bromodeoxyuridine; Centrifugation, Density Gradient; Chloramphenicol; Deoxyuridine; DNA Repair; DNA Replication; DNA, Bacterial; Escherichia coli; Mesylates; Mitomycins; Thymidine; Tritium | 1974 |
[Thymidylate synthetase in Drosophila melanogaster].
Topics: Animals; Bromodeoxyuridine; Deoxyuridine; DNA; Drosophila; Ligases; Mutagens; Nucleotides; Thymidine; Tritium; Uracil Nucleotides | 1969 |
[Gamma-radiolysis of aqueous solutions of 5-bromo-2'-deoxyuridine in presence of oxygen. I. Identification of products].
Topics: Bromodeoxyuridine; Bromouracil; Chromatography, Thin Layer; Cobalt Isotopes; Deoxyuridine; Nucleosides; Pentoses; Radiation Effects; Urea | 1971 |
[Gamma-radiolysis of aqeuous solutions of 5-Bromo-2'-deoxyuridine in presence of oxygen. II. G-values of products and comparison with the radiolysis of the aglycone].
Topics: Bromodeoxyuridine; Cobalt Isotopes; Deoxyuridine; Nucleosides; Radiation Effects; Radiochemistry; Urea | 1971 |
Mitochondrial thymidine kinase of bromodeoxyuridine-resistant, kinase-deficient HeLa(BU25) cells.
Topics: Bromodeoxyuridine; Cell Nucleus; Centrifugation, Density Gradient; Cytosol; Deoxyribonucleosides; Deoxyuridine; DNA, Neoplasm; Drug Resistance; HeLa Cells; Humans; Hydrogen-Ion Concentration; Mitochondria; Mutation; Nucleosides; Phosphoric Acids; Phosphotransferases; Thymidine Kinase; Thymine Nucleotides; Tritium | 1972 |
Debromination of 5-bromo-2'-deoxyuridine by cysteine. Formation of deoxyuridine and S-(5-(2'-deoxyuridyl))cysteine.
Topics: Bromodeoxyuridine; Carbon Radioisotopes; Cellulose; Chromatography; Chromatography, Paper; Cysteine; Deoxyuridine; Drug Stability; Electrophoresis; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Spectrophotometry, Ultraviolet; Time Factors | 1973 |
5-Ethyl-2'-deoxyuridine: evidence for incorporation into DNA and evaluation of biological properties in lymphocyte cultures grown under conditions of amethopterine-imposed thymidine deficiency.
Topics: Autoradiography; Bromodeoxyuridine; Carbon Radioisotopes; Cells, Cultured; Chromosome Aberrations; Culture Media; Deoxyuridine; DNA; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Lymphocytes; Methotrexate; Mitosis; Thymidine; Time Factors | 1973 |
The effects of mutation and nucleic acid base analogues on the sensitivity of E. coli to partial dehydration.
Topics: Aerosols; Bromodeoxyuridine; Deoxyuridine; DNA, Bacterial; Escherichia coli; Humidity; Idoxuridine; Mutation; Nucleosides; Pyrimidines; Selection, Genetic; Thiouracil; Thymine; Uridine; Water | 1968 |
The role of nucleoside phosphorylases in the degradation of deoxyribonucleosides by thymine-requiring mutants of E. coli.
Topics: Bromodeoxyuridine; Deoxyuridine; Enzyme Induction; Escherichia coli; Genetics, Microbial; Mutation; Nucleosides; Pentosephosphates; Phosphotransferases; Thymine; Thymine Nucleotides; Transferases | 1971 |
Biochemical analysis of the naturally repaired sections of bacteriophage T5 deoxyribonucleic acid. II. Conditions for nucleotide incorporation under nonpermissive conditions.
Topics: Bromodeoxyuridine; Centrifugation, Density Gradient; Chloramphenicol; Coliphages; Deoxyuridine; DNA Nucleotidyltransferases; DNA Repair; DNA Replication; DNA, Bacterial; DNA, Viral; Drug Stability; Escherichia coli; Genetics, Microbial; Isotope Labeling; Mutation; Nucleic Acid Hybridization; Phosphorus Isotopes; Temperature; Time Factors; Tritium; Virus Replication | 1971 |
Acidic hydrolysis of deoxycytidine and deoxyuridine derivatives. The general mechanism of deoxyribonucleoside hydrolysis.
Topics: Bromine; Bromodeoxyuridine; Cytidine; Deoxyribonucleosides; Deoxyuridine; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Mathematics; Methylation; Models, Chemical; Nucleosides; Spectrophotometry; Temperature; Thermodynamics; Thymidine; Ultraviolet Rays; Uracil | 1972 |
[Biochemical action of some radiosensitizing agents].
Topics: Animals; Anti-Bacterial Agents; Bromodeoxyuridine; Cells; Deoxyuridine; DNA; Enzyme Induction; Humans; Mice; Mitosis; Periodicity; Proteins; Radiation Effects; Radiation-Sensitizing Agents; RNA; Uracil | 1972 |
Purification and substrate specificity of pyrimidine nucleoside phosphorylase from Haemophilus influenzae.
Topics: Arabinose; Bromodeoxyuridine; Bromouracil; Chromatography; Chromatography, DEAE-Cellulose; Cytidine; Deoxyuridine; Dithiothreitol; Drug Stability; Electrophoresis; Glycerol; Haemophilus influenzae; Hot Temperature; Kinetics; Mathematics; Nucleosides; Pentosyltransferases; Phosphates; Spectrophotometry; Thymidine; Uracil; Uridine | 1971 |
A clonal study of the reversible inhibition of muscle differentiation by the halogenated thymidine analog 5-bromodeoxyuridine.
Topics: Animals; Autoradiography; Bromodeoxyuridine; Cell Differentiation; Chick Embryo; Clone Cells; Culture Techniques; Deoxyuridine; DNA; Horses; Immune Sera; Microscopy, Electron; Muscles; Rats; Thymidine; Tritium | 1969 |
Uncatalyzed hydrolysis of deoxyuridine, thymidine, and 5-bromodeoxyuridine.
Topics: Bromodeoxyuridine; Buffers; Chemical Phenomena; Chemistry; Deoxyuridine; Hydrogen-Ion Concentration; Kinetics; Protons; Thermodynamics; Thymidine | 1969 |
Theoretical evaluation of a limitation in the use of pyrimidine analogs in radiation therapy.
Topics: Bromodeoxyuridine; Culture Techniques; Deoxyuridine; Idoxuridine; Neoplasms; Neoplasms, Experimental; Pyrimidines; Radiation-Sensitizing Agents | 1966 |
On the influence of thymidine analogues on the activity of phage fd promoters in vitro.
Topics: Bacteriophages; Base Composition; Bromodeoxyuridine; Deoxyribonuclease HpaII; Deoxyuridine; DNA Restriction Enzymes; DNA-Directed RNA Polymerases; DNA, Viral; Escherichia coli; Kinetics; Operon; Structure-Activity Relationship; Thymidine | 1980 |
Interaction of 2'-halogeno-2'-deoxyuridines with the human erythrocyte nucleoside transport mechanism.
Topics: Binding, Competitive; Biological Transport, Active; Bromodeoxyuridine; Deoxyuridine; Erythrocyte Membrane; Erythrocytes; Floxuridine; Humans; Idoxuridine; Kinetics; Nucleosides; Structure-Activity Relationship; Thymidine | 1983 |
Differential affinities of 5-(2-halogenovinyl)-2'-deoxyuridines for deoxythymidine kinases of various origins.
Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Cytosol; Deoxyuridine; Herpesvirus 3, Human; Humans; Idoxuridine; In Vitro Techniques; Mitochondria; Phosphorylation; Rabbits; Simplexvirus; Substrate Specificity; Thymidine Kinase | 1981 |
5-Methoxymethyldeoxyuridine-resistant mutants of herpes simplex virus type 1.
Topics: Acyclovir; Animals; Arabinonucleosides; Bromodeoxyuridine; Cell Line; Deoxyuridine; Drug Resistance, Microbial; Enzyme Induction; Guanine; Mice; Mutation; Phosphonoacetic Acid; Simplexvirus; Thymidine; Thymidine Kinase | 1981 |
Differential inhibition of herpes simplex viruses, type 1 (HSV-1) an type 2 (HSV-2), by (E)-5-(2-X-vinyl)-2'-deoxyuridines.
Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Cell Line; Deoxyuridine; Fluorodeoxyuridylate; Idoxuridine; Rabbits; Simplexvirus; Structure-Activity Relationship | 1981 |
Incorporation of E-5-(2-halovinyl)-2'-deoxyuridines into deoxyribonucleic acids of herpes simplex virus type 1-infected cells.
Topics: Animals; Bromodeoxyuridine; Cell Line; Cell Transformation, Viral; Deoxyuridine; DNA Polymerase II; DNA Replication; DNA, Viral; Halogens; Idoxuridine; Kidney; Simplexvirus; Structure-Activity Relationship; Vinyl Compounds; Virus Replication | 1982 |
Virus-induced thymidine kinases as markers for typing herpes simplex viruses and for drug sensitivity assays.
Topics: Bromodeoxyuridine; Cells, Cultured; Deoxyribonucleases; Deoxyuridine; Enzyme Induction; Fluorescent Antibody Technique; HeLa Cells; Humans; Idoxuridine; Microbial Sensitivity Tests; Simplexvirus; Thymidine Kinase | 1982 |
Alterations in substrate specificity and physicochemical properties of deoxythymidine kinase of a drug-resistant herpes simplex virus type 1 mutant.
Topics: Arabinonucleosides; Blood; Bromodeoxyuridine; Deoxyuridine; Drug Resistance, Microbial; Enzyme Induction; Hot Temperature; Mutation; Phosphorylation; Simplexvirus; Substrate Specificity; Thymidine; Thymidine Kinase | 1983 |
Differential binding affinities of sugar-modified derivatives of (E)-5-(2-bromovinyl)-2'-deoxyuridine for herpes simplex virus-induced and human cellular deoxythymidine kinases.
Topics: Bromodeoxyuridine; Cytosol; Deoxyuridine; Enzyme Induction; Humans; Mitochondria; Simplexvirus; Thymidine Kinase; Virus Replication | 1984 |
DNA lesions, chromosomal aberrations and G2 delay in CHO cells cultured in medium containing bromo- or chloro-deoxyuridine.
Topics: Animals; Benzamides; Bromodeoxyuridine; Caffeine; Cell Survival; Chromosome Aberrations; Cricetinae; Cricetulus; Deoxyuridine; DNA Repair; DNA, Single-Stranded; Female; Flow Cytometry; Hydroxyurea; Interphase; Ovary; Poly(ADP-ribose) Polymerases | 1984 |
Induction of DNA lesions, chromosomal aberrations, and G2 delay by bromo- and chlorodeoxyuridine.
Topics: Animals; Bromodeoxyuridine; Cell Line; Chromosome Aberrations; Cricetinae; Cricetulus; Deoxyuridine; DNA; Female; Fibroblasts; Humans; Interphase; Leukemia L5178; Mice; Ovary; Poly(ADP-ribose) Polymerases; Skin | 1984 |
Probing sister chromatid exchange formation with halogenated pyrimidines.
Topics: Animals; Bone Marrow; Bromodeoxycytidine; Bromodeoxyuridine; Deoxycytidine; Deoxyuridine; Humans; Idoxuridine; Lymphocytes; Mice; Models, Genetic; Pyrimidines; Rabbits; Sister Chromatid Exchange | 1984 |
The replication of unsubstituted and 5-bromodeoxyuridine- or 5-chlorodeoxyuridine-substituted DNA regulates the rate of induction of sister chromatid exchanges.
Topics: Animals; Bromodeoxyuridine; Cell Line; Cricetinae; Deoxyuridine; DNA Replication; Female; Fibroblasts; Ovary; Sister Chromatid Exchange; Templates, Genetic | 1984 |
Phosphorolysis of (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU) and other 5-substituted-2'-deoxyuridines by purified human thymidine phosphorylase and intact blood platelets.
Topics: Blood Platelets; Bromodeoxyuridine; Bromouracil; Chromatography, High Pressure Liquid; Deoxyuridine; Humans; In Vitro Techniques; Pentosyltransferases; Thymidine Phosphorylase; Thymine | 1983 |
Sister-chromatid exchanges and gene mutations are induced by the replication of 5-bromo- and 5-chloro-deoxyuridine substituted DNA.
Topics: Animals; Bromodeoxyuridine; Cells, Cultured; Cricetinae; Cricetulus; Crossing Over, Genetic; Deoxyuridine; DNA Replication; Female; Mutation; Ovary; Sister Chromatid Exchange | 1983 |
In vivo SCE analysis using bromodeoxyuridine, iododeoxyuridine, and chlorodeoxyuridine.
Topics: Animals; Bone Marrow Cells; Bromodeoxyuridine; Crossing Over, Genetic; Deoxyuridine; Idoxuridine; Mice; Rabbits; Sister Chromatid Exchange | 1984 |
Synthesis and biological properties of some cyclic phosphotriesters derived from 2'-deoxy-5-fluorouridine.
Topics: Animals; Antimetabolites, Antineoplastic; Bromodeoxyuridine; Deoxycytidine; Deoxyuridine; Drug Resistance; Indicators and Reagents; Leukemia L1210; Mice; Organophosphorus Compounds; Structure-Activity Relationship; Thymidine; Thymidine Monophosphate | 1984 |
Quantification of the induction of SCE due to the replication of unsubstituted and BrdU- or CldU-substituted DNA in CHO cells.
Topics: Animals; Bromodeoxyuridine; Cells, Cultured; Cricetinae; Crossing Over, Genetic; Deoxyuridine; DNA Replication; Female; Ovary; Sister Chromatid Exchange | 1984 |
SCE induction is proportional to substitution in DNA for thymidine by CldU and BrdU.
Topics: Animals; Bromodeoxyuridine; Cell Line; Cricetinae; Cricetulus; Crossing Over, Genetic; Deoxyuridine; DNA; Female; Kinetics; Ovary; Sister Chromatid Exchange; Thymidine | 1983 |
The synthesis and properties of some 5-substituted uracil derivatives.
Topics: Bromodeoxyuridine; Chemical Phenomena; Chemistry; Coliphages; Deoxyuridine; DNA, Bacterial; DNA, Viral; Escherichia coli; Methods; Mycoplasma; Uracil | 1980 |
The induction of specific-locus mutations and sister-chromatid exchanges by 5-bromo- and 5-chloro-deoxyuridine.
Topics: Animals; Bromodeoxyuridine; Cell Line; Chromosome Mapping; Chromosomes; Cricetinae; Cricetulus; Crossing Over, Genetic; Deoxyuridine; Drug Resistance; Female; Mutagens; Mutation; Ovary; Sister Chromatid Exchange; Thioguanine | 1982 |
The influence of incorporated halogenated analogues of thymidine on the sister-chromatid exchange frequency in human lymphocytes.
Topics: Bromodeoxyuridine; Cell Division; Cells, Cultured; Crossing Over, Genetic; Deoxyuridine; Female; Humans; Idoxuridine; Lymphocytes; Male; Sister Chromatid Exchange; Structure-Activity Relationship | 1981 |
The synthesis and properties of some 5-substituted uracil derivatives.
Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Deoxyuridine; Drug Evaluation, Preclinical; Herpesviridae; Structure-Activity Relationship; Uracil | 1981 |
Pharmacokinetics and bioavailability of 5-ethyl-2'-deoxyuridine and its novel (5R,6R)-5-bromo-6-ethoxy-5,6-dihydro prodrugs in mice.
Topics: Administration, Oral; Animals; Antiviral Agents; Biological Availability; Bromodeoxyuridine; Deoxyuridine; Injections, Intravenous; Male; Mice; Mice, Inbred BALB C; Prodrugs | 1995 |
Stereoelectronic properties of five anti-HSV-1 2'-deoxynucleosides analogues with heterocyclic substituents in the 5-position: a comparison with BVDU.
Topics: Antiviral Agents; Bromodeoxyuridine; Chemical Phenomena; Chemistry, Physical; Deoxyuridine; Herpesvirus 1, Human; Molecular Structure; Stereoisomerism; Thermodynamics; Thiophenes; Thymidine Kinase; Viral Proteins; X-Ray Diffraction | 1994 |
Analysis of the thymidine kinase of a herpes simplex virus type 1 isolate that exhibits resistance to (E)-5-(2-bromovinyl)-2'-deoxyuridine.
Topics: Acyclovir; Amino Acid Sequence; Antiviral Agents; Base Sequence; Binding Sites; Bromodeoxyuridine; Deoxyuridine; Drug Resistance, Microbial; Herpesvirus 1, Human; Humans; Kinetics; Molecular Sequence Data; Phosphonoacetic Acid; Phosphorylation; Point Mutation; Sequence Analysis, DNA; Thymidine; Thymidine Kinase; Vidarabine | 1994 |
5-Propyl-2-deoxyuridine induced interference with glycosylation in herpes simplex virus infected cells. Nature of PdU-induced modifications of N-linked glycans.
Topics: Agglutinins; Animals; Antiviral Agents; Biological Transport; Bromodeoxyuridine; Cell Line; Chlorocebus aethiops; Chromatography, Affinity; Chromatography, Gel; Deoxyuridine; Glycosylation; Golgi Apparatus; Humans; Infant; Lectins; Melanoma, Experimental; Mice; Neuraminidase; Nucleoside Diphosphate Sugars; Polysaccharides; Simplexvirus; Tumor Cells, Cultured; Viral Envelope Proteins | 1993 |
Efficacy of (S)-HPMPA against thymidine kinase-deficient herpes simplex virus-keratitis.
Topics: Adenine; Administration, Topical; Animals; Antiviral Agents; Bromodeoxyuridine; Deoxyuridine; Herpesvirus 1, Human; Keratitis, Herpetic; Ophthalmic Solutions; Organophosphonates; Organophosphorus Compounds; Rabbits; Thymidine Kinase | 1987 |
[Cytogenetic anomalies in cultured human lymphocytes exposed to halogen analogs of thymidine].
Topics: Adult; Bromodeoxyuridine; Cells, Cultured; Chromosome Aberrations; Deoxyuridine; Female; Humans; Idoxuridine; Lymphocytes; Male; Mutagens | 1995 |
[Halogenated analogs of thymidine increase the level of chromosome aberrations in patients with Fanconi's anemia].
Topics: Adolescent; Bromodeoxyuridine; Chromosome Aberrations; Deoxyuridine; Fanconi Anemia; Humans; In Vitro Techniques; Male; Mutagens | 1996 |
Glioma cells transduced with an Escherichia coli CD/HSV-1 TK fusion gene exhibit enhanced metabolic suicide and radiosensitivity.
Topics: Blotting, Western; Bromodeoxyuridine; Cytosine; Cytosine Deaminase; Deoxyuridine; Enzyme Inhibitors; Escherichia coli; Flucytosine; Ganciclovir; Gene Expression Regulation, Viral; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Gliosarcoma; Humans; Nucleoside Deaminases; Prodrugs; Radiation Tolerance; Recombinant Fusion Proteins; Simplexvirus; Thymidine Kinase; Tumor Cells, Cultured | 1997 |
Radiolytic products of bromodeoxyuridine in solids by 60Co gamma-rays and monoenergetic soft x-rays at the K-absorption edge of bromine.
Topics: Bromodeoxyuridine; Bromouracil; Chromatography, High Pressure Liquid; Cobalt Radioisotopes; Deoxyuridine; Linear Energy Transfer; Magnetic Resonance Spectroscopy; X-Rays | 1996 |
Modification of potentially lethal damage in irradiated Chinese hamster V79 cells after incorporation of halogenated pyrimidines.
Topics: Animals; Bromodeoxyuridine; Cell Division; Cell Survival; Cells, Cultured; Cricetinae; Cricetulus; Deoxyuridine; DNA; Dose-Response Relationship, Radiation; Fibroblasts; Idoxuridine; Radiation Injuries, Experimental; Radiation Tolerance; Radiation-Sensitizing Agents | 1997 |
Hyperthermia and incorporation of halogenated pyrimidines: radiosensitization in cultured rodent and human tumor cells.
Topics: Animals; Bromodeoxyuridine; Cell Survival; Combined Modality Therapy; Cricetinae; Deoxyuridine; Drug Screening Assays, Antitumor; Humans; Hyperthermia, Induced; Idoxuridine; Radiation-Sensitizing Agents; Rats; Tumor Cells, Cultured | 1997 |
Relaxed enantioselectivity of human mitochondrial thymidine kinase and chemotherapeutic uses of L-nucleoside analogues.
Topics: Binding, Competitive; Bromodeoxyuridine; Cyclopentanes; Cytosol; Deoxycytidine; Deoxycytidine Kinase; Deoxyuridine; HeLa Cells; Humans; Mitochondria; Phosphorylation; Stereoisomerism; Substrate Specificity; Thymidine; Thymidine Kinase | 1997 |
Structure and dynamics of human interphase chromosome territories in vivo.
Topics: Bromodeoxyuridine; Carbocyanines; Cell Nucleus; Chromosome Mapping; Chromosomes, Human; Deoxyuracil Nucleotides; Deoxyuridine; DNA Replication; Fibroblasts; Fluorescent Dyes; HeLa Cells; Humans; Idoxuridine; Interphase; Microscopy, Fluorescence; Neuroblastoma; Thymidine; Tumor Cells, Cultured | 1998 |
[Chromosomal abnormalities in lymphocytes from a patient with Werner's syndrome in intact culture and after treatment with halogenated analogs of thymidine].
Topics: Adult; Bromodeoxyuridine; Chromosome Aberrations; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 15; Deoxyuridine; Humans; Idoxuridine; Lymphocytes; Male; Nucleic Acid Synthesis Inhibitors; Werner Syndrome | 2002 |
5-BROMODEOXYURIDINE: EFFECT ON MYOGENESIS IN VITRO.
Topics: Animals; Bromodeoxyuridine; Cells, Cultured; Chick Embryo; Deoxyuridine; DNA; In Vitro Techniques; Metabolism; Muscle Development; Muscles; Myosins; Nucleosides; Pharmacology; Research; Thymidine; Tritium | 1964 |
TEMPERATURE-SENSITIVE MUTANTS OF COLIPHAGE LAMBDA.
Topics: Bacteriophage lambda; Bromodeoxyuridine; Coliphages; Deoxyuridine; Genetics; Hydroxylamines; Mutagens; Mutation; Research; Temperature; Thymidine | 1964 |
PROPERTIES OF DEOXYTHYMIDINE KINASE PARTIALLY PURIFIED FROM NONINFECTED MOUSE FIBROBLAST CELLS.
Topics: Animals; Bromodeoxyuridine; Cell Division; Deoxyuridine; Enzyme Inhibitors; Fibroblasts; Floxuridine; Immune Sera; Kinetics; Mice; Nucleotides; Phosphotransferases; Rabbits; Research; Simplexvirus; Thymidine; Thymidine Kinase; Tritium; Uridine; Vaccinia virus | 1965 |
Neural stem cell detection, characterization, and age-related changes in the subventricular zone of mice.
Topics: Administration, Oral; Aging; Animals; Antigens, Differentiation; Bromodeoxyuridine; Cell Count; Cell Cycle; Cell Division; Cells, Cultured; Cytarabine; Deoxyuridine; Glial Fibrillary Acidic Protein; Idoxuridine; Intermediate Filament Proteins; Lateral Ventricles; Male; Mice; Minichromosome Maintenance Complex Component 2; Nerve Tissue Proteins; Nestin; Neurons; Nuclear Proteins; Stem Cells | 2004 |
Reductive electron transfer in phenothiazine-modified DNA is dependent on the base sequence.
Topics: Base Pairing; Base Sequence; Bromodeoxyuridine; Deoxyuridine; DNA; Electrons; Kinetics; Molecular Sequence Data; Molecular Structure; Oligonucleotides; Oxidation-Reduction; Phenothiazines | 2005 |
Discrimination of cell nuclei in early S-phase, mid-to-late S-phase, and G(2)/M-phase by sequential administration of 5-bromo-2'-deoxyuridine and 5-chloro-2'-deoxyuridine.
Topics: Animals; Bromodeoxyuridine; Cell Nucleus; Cells, Cultured; Deoxyuridine; DNA Replication; G2 Phase; Immunohistochemistry; Indicators and Reagents; Intestine, Small; Male; Mice; S Phase | 2005 |
The Escherichia coli protein YjjG is a house-cleaning nucleotidase in vivo.
Topics: Azacitidine; Bromodeoxyuridine; Decitabine; Deoxyuridine; DNA Damage; Escherichia coli; Escherichia coli Proteins; Fluorouracil; Models, Biological; Molecular Structure; Mutation; N-Glycosyl Hydrolases; Nucleotidases; Orotic Acid; Substrate Specificity; Thymidine Monophosphate; Uridine | 2007 |
High incidence of non-random template strand segregation and asymmetric fate determination in dividing stem cells and their progeny.
Topics: Animals; Bromodeoxyuridine; Cell Differentiation; Cell Division; Chromosome Segregation; Deoxyuridine; DNA Replication; Idoxuridine; Mice; Muscles; Rats; Regeneration; Satellite Cells, Skeletal Muscle; Stem Cells | 2007 |
Label-retaining cells in the rat submandibular gland.
Topics: Actins; Animals; Biomarkers; Bromodeoxyuridine; Cell Count; Cell Lineage; Deoxyuridine; Fluorescent Dyes; Idoxuridine; Immunohistochemistry; Keratin-18; Rats; Rats, Wistar; Regeneration; Stem Cells; Submandibular Gland | 2008 |
Use of halogenated precursors for simultaneous DNA and RNA detection by means of immunoelectron and immunofluorescence microscopy.
Topics: Animals; Antibodies; Bromodeoxyuridine; CHO Cells; Cricetinae; Cricetulus; Cross Reactions; Deoxyuridine; DNA; Idoxuridine; Microscopy, Fluorescence; Microscopy, Immunoelectron; RNA | 2008 |
Replication labeling with halogenated thymidine analogs.
Topics: Animals; Bromodeoxyuridine; Deoxyuridine; DNA Replication; Idoxuridine; In Situ Hybridization, Fluorescence; Indicators and Reagents; Mammals; Microscopy, Fluorescence; Replication Origin; S Phase | 2007 |
A novel method based on click chemistry, which overcomes limitations of cell cycle analysis by classical determination of BrdU incorporation, allowing multiplex antibody staining.
Topics: Animals; Antibodies; Bone Marrow Cells; Bromodeoxyuridine; Caspase 3; Cell Cycle; Deoxyuridine; Flow Cytometry; Histones; HL-60 Cells; Humans; Male; Mice; Mice, Inbred BALB C; Models, Biological | 2008 |
Detection of S-phase cell cycle progression using 5-ethynyl-2'-deoxyuridine incorporation with click chemistry, an alternative to using 5-bromo-2'-deoxyuridine antibodies.
Topics: Antibodies; Bromodeoxyuridine; Deoxyuridine; DNA; Flow Cytometry; Humans; Jurkat Cells; S Phase | 2008 |
Antiviral activities and phosphorylation of 5-halo-2'-deoxyuridines and N-methanocarbathymidine in cells infected with vaccinia virus.
Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Cell Line, Tumor; Chlorocebus aethiops; Deoxyuridine; Floxuridine; Humans; Idoxuridine; Mice; Phosphorylation; Thymidine; Thymidine Kinase; Vaccinia; Vaccinia virus; Vero Cells; Viral Plaque Assay | 2008 |
Noggin expands neural stem cells in the adult hippocampus.
Topics: Adult Stem Cells; Analysis of Variance; Animals; Bone Morphogenetic Protein 4; Bone Morphogenetic Proteins; Bromodeoxyuridine; Carrier Proteins; Cell Differentiation; Cells, Cultured; Deoxyuridine; Glial Fibrillary Acidic Protein; Hippocampus; Idoxuridine; Intercellular Signaling Peptides and Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microtubule-Associated Proteins; Neural Cell Adhesion Molecule L1; Neurofilament Proteins; Nucleic Acid Synthesis Inhibitors; O Antigens; Phosphopyruvate Hydratase; Sialic Acids; Telomerase | 2008 |
Cell type specific applicability of 5-ethynyl-2'-deoxyuridine (EdU) for dynamic proliferation assessment in flow cytometry.
Topics: Apoptosis; Bromodeoxyuridine; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclin B; Cyclin B1; Deoxyuridine; DNA; Female; Flow Cytometry; Histones; Humans; Phosphorylation | 2009 |
Mitochondrial DNA (mtDNA) biogenesis: visualization and duel incorporation of BrdU and EdU into newly synthesized mtDNA in vitro.
Topics: Animals; Bromodeoxyuridine; Cell Line, Tumor; Deoxyuridine; DNA, Mitochondrial; Humans; Mice; Molecular Imaging; Neurons; Staining and Labeling | 2010 |
Evaluation of 5-ethynyl-2'-deoxyuridine staining as a sensitive and reliable method for studying cell proliferation in the adult nervous system.
Topics: Aging; Animals; Bromodeoxyuridine; Cell Count; Cell Proliferation; Cytological Techniques; Dentate Gyrus; Deoxyuridine; Dose-Response Relationship, Drug; Female; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Neurogenesis; Neurons; Physical Conditioning, Animal; Random Allocation; Restraint, Physical; Staining and Labeling; Stress, Psychological | 2010 |
Highly efficient and facile synthesis of 5-azido-2'-deoxyuridine.
Topics: Azides; Benzylamines; Bromodeoxyuridine; Deoxyuridine; Models, Chemical; Oxidation-Reduction; Photoaffinity Labels | 2010 |
Dynamic proliferation assessment in flow cytometry.
Topics: Animals; Bisbenzimidazole; Bromodeoxyuridine; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cells; Deoxyuridine; Flow Cytometry; Humans | 2010 |
Molecular mechanism of the DNA sequence selectivity of 5-halo-2'-deoxyuridines as potential radiosensitizers.
Topics: Bromodeoxyuridine; Deoxyuridine; DNA; Kinetics; Radiation-Sensitizing Agents; RNA | 2010 |
Dual-pulse labeling using 5-ethynyl-2'-deoxyuridine (EdU) and 5-bromo-2'-deoxyuridine (BrdU) in flow cytometry.
Topics: Bromodeoxyuridine; Cell Proliferation; Cells; Click Chemistry; Deoxyuridine; Flow Cytometry; Humans; Methods; Molecular Probe Techniques; S Phase; Staining and Labeling | 2011 |
Compensation of depleted neuronal subsets by new neurons in a local area of the adult olfactory bulb.
Topics: Animals; Animals, Newborn; Bromodeoxyuridine; Calbindin 2; Cell Count; Cell Movement; Cell Transplantation; Cerebral Ventricles; Dendritic Spines; Deoxyuridine; Doublecortin Domain Proteins; Female; Gene Expression Regulation; Glutamate Decarboxylase; Green Fluorescent Proteins; Humans; Idoxuridine; Immunotoxins; In Situ Nick-End Labeling; Interleukin-2 Receptor alpha Subunit; Luminescent Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microtubule-Associated Proteins; Neurogenesis; Neurons; Neuropeptides; Olfactory Bulb; Receptors, Metabotropic Glutamate; S100 Calcium Binding Protein G; Statistics, Nonparametric; Synapses; Time Factors; Transduction, Genetic; Vesicular Glutamate Transport Protein 1 | 2011 |
The opiate analgesic buprenorphine decreases proliferation of adult hippocampal neuroblasts and increases survival of their progeny.
Topics: Adult Stem Cells; Analgesics; Analysis of Variance; Animals; Antigens; Bromodeoxyuridine; Buprenorphine; Cell Proliferation; Cell Survival; Deoxyuridine; Doublecortin Domain Proteins; Glial Fibrillary Acidic Protein; Hippocampus; In Situ Nick-End Labeling; Male; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins; Neurogenesis; Neuroglia; Neuropeptides; Phosphopyruvate Hydratase; Proteoglycans; Time Factors | 2012 |
Dynamic metabolic labeling of DNA in vivo with arabinosyl nucleosides.
Topics: 3T3 Cells; Animals; Bromodeoxyuridine; Cell Cycle; Cell Proliferation; Chlorocebus aethiops; Deoxyuridine; Developmental Biology; DNA; Dose-Response Relationship, Drug; Fertilization; Fluorescent Dyes; HeLa Cells; Humans; Mice; Models, Chemical; Nucleosides; Vero Cells; Zebrafish | 2011 |
Cell fate control gene therapy based on engineered variants of human deoxycytidine kinase.
Topics: Animals; Bromodeoxyuridine; Catalytic Domain; Cell Line, Tumor; Deoxycytidine Kinase; Deoxyuridine; Enzyme Activation; Genetic Engineering; Genetic Therapy; Genetic Vectors; Humans; Lentivirus; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasms; Primary Cell Culture; Prodrugs; T-Lymphocytes; Thymidine; Transduction, Genetic; Xenograft Model Antitumor Assays | 2012 |
The sub-cellular localization of Sulfolobus DNA replication.
Topics: Bromodeoxyuridine; Cell Cycle; Deoxyuridine; DNA Replication; DNA-Directed DNA Polymerase; DNA, Archaeal; Multienzyme Complexes; Sulfolobus acidocaldarius; Sulfolobus solfataricus | 2012 |
Environmental enrichment increases the GFAP+ stem cell pool and reverses hypoxia-induced cognitive deficits in juvenile mice.
Topics: Analysis of Variance; Animals; Animals, Newborn; Bromodeoxyuridine; Cell Count; Cell Differentiation; Cognition Disorders; Deoxyuridine; Disease Models, Animal; Environment; Estrogen Antagonists; Female; Gene Expression Regulation, Developmental; Glial Fibrillary Acidic Protein; Green Fluorescent Proteins; Humans; Hypoxia; Idoxuridine; Ki-67 Antigen; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Tissue Proteins; Neurogenesis; Neuroglia; Receptors, Estrogen; Stem Cells; Tamoxifen | 2012 |
Regulation of p27Kip1 by Sox2 maintains quiescence of inner pillar cells in the murine auditory sensory epithelium.
Topics: Age Factors; Animals; Animals, Newborn; Bromodeoxyuridine; Cell Cycle; Cell Differentiation; Cell Line, Transformed; Cell Proliferation; Chromatin Immunoprecipitation; Cochlea; Cyclin-Dependent Kinase Inhibitor p27; Deoxyuridine; Gene Expression Regulation, Developmental; Hair Cells, Auditory; Homeodomain Proteins; Humans; In Situ Nick-End Labeling; Labyrinth Supporting Cells; Luminescent Proteins; Mice; Mice, Transgenic; Myosin Heavy Chains; Receptor, Fibroblast Growth Factor, Type 3; SOXB1 Transcription Factors; Tamoxifen; Transfection; Tumor Suppressor Proteins | 2012 |
Multicolor flow cytometry analysis of the proliferations of T-lymphocyte subsets in vitro by EdU incorporation.
Topics: Animals; Biological Transport; Bromodeoxyuridine; Cell Proliferation; Cells, Cultured; Click Chemistry; Deoxyuridine; Fixatives; Flow Cytometry; Lymphocyte Count; Mice; Mice, Inbred C57BL; Spleen; Staining and Labeling; T-Lymphocyte Subsets; Thymidine | 2012 |
Differential gene expression in nuclear label-retaining cells in the developing mouse mammary gland.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Blotting, Western; Bromodeoxyuridine; Cell Line; Cell Nucleus; Cell Proliferation; Cells, Cultured; Deoxyuridine; Female; Fluorescent Antibody Technique; Gene Expression Profiling; Gene Expression Regulation, Developmental; Homeodomain Proteins; Mammary Glands, Animal; Mice; Mice, Inbred BALB C; Receptor, Notch1; Receptor, Notch2; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Signal Transduction; Staining and Labeling; Stem Cells; Transcription Factor HES-1; Wnt Signaling Pathway | 2013 |
Most anti-BrdU antibodies react with 2'-deoxy-5-ethynyluridine -- the method for the effective suppression of this cross-reactivity.
Topics: Antibodies; Antibody Affinity; Biological Transport; Biotinylation; Bromodeoxyuridine; Cross Reactions; Deoxyuridine; DNA; Fluorescent Dyes; HeLa Cells; Humans; Microscopy, Fluorescence; Staining and Labeling | 2012 |
Stem cell survival is severely compromised by the thymidineanalog EdU (5-ethynyl-2'-deoxyuridine), an alternative to BrdU for proliferation assays and stem cell tracing.
Topics: Animals; Bromodeoxyuridine; Cell Proliferation; Cell Survival; Cell Tracking; Deoxyuridine; Humans; Rats; Staining and Labeling; Stem Cells | 2013 |
Cell-cycle analyses using thymidine analogues in fission yeast.
Topics: Bromodeoxyuridine; Cell Cycle; Cell Proliferation; Deoxyuridine; DNA Replication; DNA, Fungal; Schizosaccharomyces; Staining and Labeling; Thymidine | 2014 |
Assessing cell cycle progression of neural stem and progenitor cells in the mouse developing brain after genotoxic stress.
Topics: Animals; Brain; Bromodeoxyuridine; Cell Cycle; Deoxyuridine; DNA Damage; Female; G1 Phase Cell Cycle Checkpoints; Mice; Microscopy, Fluorescence; Neural Stem Cells; Pregnancy; S Phase Cell Cycle Checkpoints; Stem Cells; Whole-Body Irradiation | 2014 |
Identification of potential bladder progenitor cells in the trigone.
Topics: Animals; Bromodeoxyuridine; Cell Differentiation; Deoxyuridine; Female; Mice; Staining and Labeling; Stem Cells; Urinary Bladder; Urothelium | 2014 |
Dual labeling with 5-bromo-2'-deoxyuridine and 5-ethynyl-2'-deoxyuridine for estimation of cell migration rate in the small intestinal epithelium.
Topics: Animals; Bromodeoxyuridine; Cell Movement; Deoxyuridine; Intestinal Mucosa; Intestine, Small; Male; Rats; Rats, Wistar; Staining and Labeling | 2015 |
Application of click chemistry conditions for 5-bromo-2'-deoxyuridine determination through Fenton and related reactions.
Topics: Bromodeoxyuridine; Catalysis; Cell Line, Tumor; Cell Proliferation; Click Chemistry; Deoxyuridine; DNA; Flow Cytometry; Humans; Hydrogen Peroxide; Immunohistochemistry; Iron; Staining and Labeling | 2015 |
Cell Proliferation Method: Click Chemistry Based on BrdU Coupling for Multiplex Antibody Staining.
Topics: Animals; Antibodies; Bromodeoxyuridine; Cell Proliferation; Click Chemistry; Cycloaddition Reaction; Deoxyuridine; DNA; Flow Cytometry; Fluorescent Antibody Technique; Humans; Mice, Inbred BALB C; Staining and Labeling | 2015 |
A novel multicolor immunostaining method using ethynyl deoxyuridine for analysis of in situ immunoproliferative response.
Topics: Animals; Antimetabolites; Bromodeoxyuridine; CD28 Antigens; Cell Proliferation; Dendritic Cells; Deoxyuridine; Flow Cytometry; Immunity, Cellular; Immunohistochemistry; Lymphocytes; Major Histocompatibility Complex; Male; Rats; Rats, Inbred Lew; S Phase; Spleen; Transcription Factors | 2015 |
Analysis of Cell Proliferation and Homeostasis Using EdU Labeling.
Topics: Biomarkers; Bromodeoxyuridine; Cell Proliferation; Deoxyuridine; DNA Replication; Flow Cytometry; Homeostasis; S Phase; Staining and Labeling | 2016 |
Bromopyridone Nucleotide Analogues, Anoxic Selective Radiosensitizing Agents That Are Incorporated in DNA by Polymerases.
Topics: Base Sequence; Bromodeoxyuridine; Cross-Linking Reagents; Deoxyuridine; DNA; DNA Damage; DNA-Directed DNA Polymerase; Humans; Nucleotides; Pyridones; Radiation-Sensitizing Agents; Solid-Phase Synthesis Techniques; Ultraviolet Rays | 2015 |
Kinetics of Label Retaining Cells in the Developing Rat Kidneys.
Topics: Animals; Biomarkers; Bromodeoxyuridine; Cell Differentiation; Cell Lineage; Cell Proliferation; Deoxyuridine; Fluorescent Antibody Technique; Image Processing, Computer-Assisted; Kidney; Kinetics; Male; Organogenesis; Rats; Rats, Sprague-Dawley; Staining and Labeling; Stem Cells | 2015 |
Dr Jekyll and Mr Hyde: a strange case of 5-ethynyl-2'-deoxyuridine and 5-ethynyl-2'-deoxycytidine.
Topics: Antibodies; Bromodeoxyuridine; Cell Death; Cell Line, Tumor; Cell Nucleus; Cytidine Deaminase; Deoxycytidine; Deoxyuridine; DNA; DNA Replication; Humans; Metabolome; RNA, Small Interfering | 2016 |
EdU and BrdU incorporation resolve their differences.
Topics: Bromodeoxyuridine; Deoxyuridine; Staining and Labeling | 2016 |
Subnuclear localization, rates and effectiveness of UVC-induced unscheduled DNA synthesis visualized by fluorescence widefield, confocal and super-resolution microscopy.
Topics: Bromodeoxyuridine; Cell Nucleus; Cells, Cultured; Deoxyuridine; DNA; Dose-Response Relationship, Radiation; Fibroblasts; Fluorescence; Humans; Microscopy, Confocal; Nucleic Acid Denaturation; Subcellular Fractions; Time Factors; Ultraviolet Rays | 2016 |
In Situ Labeling of Mitochondrial DNA Replication in Drosophila Adult Ovaries by EdU Staining.
Topics: Animals; Bromodeoxyuridine; Deoxyuridine; DNA Replication; DNA, Mitochondrial; Drosophila; Female; Oogenesis; Ovary; Staining and Labeling | 2016 |
Studies of HVC Plasticity in Adult Canaries Reveal Social Effects and Sex Differences as Well as Limitations of Multiple Markers Available to Assess Adult Neurogenesis.
Topics: Aging; Animals; Biomarkers; Brain; Bromodeoxyuridine; Canaries; Corticosterone; Deoxyuridine; Doublecortin Domain Proteins; Female; Linear Models; Male; Microtubule-Associated Proteins; Neurogenesis; Neuronal Plasticity; Neurons; Neuropeptides; Sex Characteristics; Social Behavior; Vocalization, Animal | 2017 |
Differences in the Detection of BrdU/EdU Incorporation Assays Alter the Calculation for G1, S, and G2 Phases of the Cell Cycle in Trypanosomatids.
Topics: Bromodeoxyuridine; Cell Cycle; Deoxyuridine; DNA Replication; Leishmania; Staining and Labeling; Trypanosoma | 2017 |
Lack of Methyl-CpG Binding Protein 2 (MeCP2) Affects Cell Fate Refinement During Embryonic Cortical Development.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Bromodeoxyuridine; Cells, Cultured; Cerebral Cortex; Cyclin D1; Deoxyuridine; Embryo, Mammalian; Epidermal Growth Factor; Female; Fibroblast Growth Factors; Gene Expression Regulation, Developmental; Luminescent Proteins; Male; Methyl-CpG-Binding Protein 2; Mice; Mice, Transgenic; Nerve Tissue Proteins; Neurogenesis; Neurons; Pregnancy; Proliferating Cell Nuclear Antigen; RNA, Messenger | 2018 |
Comparison of ventral organ development across Pycnogonida (Arthropoda, Chelicerata) provides evidence for a plesiomorphic mode of late neurogenesis in sea spiders and myriapods.
Topics: Animal Structures; Animals; Arthropods; Asymmetric Cell Division; Bromodeoxyuridine; Cell Movement; Cell Proliferation; Deoxyuridine; Larva; Neurogenesis; Neurons; Phylogeny; Species Specificity | 2018 |
Ablation of proliferating neural stem cells during early life is sufficient to reduce adult hippocampal neurogenesis.
Topics: Age Factors; Animals; Animals, Newborn; Antiviral Agents; Bromodeoxyuridine; Cell Proliferation; Deoxyuridine; Doublecortin Domain Proteins; Female; Gene Expression Regulation, Developmental; Glial Fibrillary Acidic Protein; Hippocampus; Ki-67 Antigen; Luminescent Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microtubule-Associated Proteins; Nestin; Neural Stem Cells; Neurogenesis; Neurons; Neuropeptides; S100 Calcium Binding Protein beta Subunit; Sex Characteristics; Valganciclovir | 2018 |
Cell Cycle Analysis Using In Vivo Staining of DNA-Synthesizing Cells.
Topics: Animals; Bone Marrow Cells; Bromodeoxyuridine; Cell Cycle; Cell Differentiation; Data Analysis; Deoxyuridine; DNA; Flow Cytometry; Immunophenotyping; Mice; Mitosis; Rheology; S Phase; Staining and Labeling | 2020 |
A Hybrid Detection Method Based on Peroxidase-mediated Signal Amplification and Click Chemistry for Highly Sensitive Background-free Immunofluorescent Staining.
Topics: Animals; Azides; Boron Compounds; Brain Chemistry; Bromodeoxyuridine; Carbocyanines; Cells, Cultured; Click Chemistry; Copper; Deoxyuridine; DNA; Female; Fluorescent Antibody Technique; Fluorescent Dyes; Horseradish Peroxidase; Humans; Male; Mice; Pluripotent Stem Cells; Sensitivity and Specificity; Tyramine | 2019 |
Evaluating the Genotoxic and Cytotoxic Effects of Thymidine Analogs, 5-Ethynyl-2'-Deoxyuridine and 5-Bromo-2'-Deoxyurdine to Mammalian Cells.
Topics: A549 Cells; Animals; Bromodeoxyuridine; CHO Cells; Cricetulus; Deoxyuridine; DNA Repair; Genes, BRCA2; Humans; Mutagenicity Tests | 2020 |
The bioavailability time of commonly used thymidine analogues after intraperitoneal delivery in mice: labeling kinetics in vivo and clearance from blood serum.
Topics: Animals; Biological Availability; Bromodeoxyuridine; Dentate Gyrus; Deoxyuridine; Glyburide; Injections, Intraperitoneal; Kinetics; Mice; Mice, Inbred C57BL; Thymidine | 2022 |
A sensitive and less cytotoxic assay for identification of proliferating T cells based on bioorthogonally-functionalized uridine analogue.
Topics: Antineoplastic Agents; Bromodeoxyuridine; Cell Proliferation; Deoxyuridine; Flow Cytometry; Staining and Labeling; T-Lymphocytes; Uridine | 2022 |
Monitoring Cellular Proliferation, Migration, and Apoptosis Associated with Atherosclerosis Plaques In Vitro.
Topics: Apoptosis; Atherosclerosis; Bromodeoxyuridine; Cell Proliferation; Deoxyuridine; Endothelial Cells; Humans | 2022 |