bromochloroacetic-acid has been researched along with cytidylyl-3--5--guanosine* in 1 studies
1 other study(ies) available for bromochloroacetic-acid and cytidylyl-3--5--guanosine
Article | Year |
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Sequence of EndoA gene encoding mouse cytokeratin and its methylation state in the CpG-rich region.
A genomic clone obtained from mouse liver DNA using a mouse cytokeratin EndoA cDNA probe revealed the complete sequence of the EndoA gene. The gene is divided into nine exons and the exon-intron pattern has been conserved compared to that of other type-II cytokeratin-encoding genes. The 5' upstream, 3' downstream and first and third introns contain potential regulatory sequences, including polyoma virus enhancer motifs (PEA1 and PEA3) and AP-1 elements. The 5' regions upstream of the EndoA, EndoB and Ck8 genes contain homologous sequences surrounding the TATA boxes. In addition, a CpG dinucleotide cluster region was located around the first exon. This CpG cluster region was found to be hypomethylated in endodermal PYS-2 cells, retinoic acid-treated F9 cells, and F9 embryonal carcinoma cells, but hypermethylated in BALB/C 3T3 fibroblast cells that do not express EndoA. These findings may provide a clue to understanding the molecular mechanisms of EndoA gene expression. Topics: Animals; Base Sequence; Dinucleoside Phosphates; DNA; Humans; Introns; Keratins; Methylation; Mice; Molecular Sequence Data; Regulatory Sequences, Nucleic Acid; Restriction Mapping; Sequence Homology, Nucleic Acid | 1991 |