bromochloroacetic-acid has been researched along with aluminum-fluoride* in 1 studies
1 other study(ies) available for bromochloroacetic-acid and aluminum-fluoride
Article | Year |
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Agonist-induced hydrolysis of phosphoinositides and formation of 1,2-diacylglycerol in adult human keratinocytes.
The ability of a variety of agonists to induce formation of inositol phosphates and 1,2-diacylglycerol in cultured adult human keratinocytes has been investigated. Histamine, bradykinin, and thrombin significantly stimulated formation of inositol mono-, bis-, and trisphosphate and 1,2-diacylglycerol within 5 min after addition. Aluminum fluoride also caused a dose-dependent accumulation of inositol phosphates suggesting the participation of a GTP binding protein in the regulation of phospholipase C-catalyzed phosphoinositide hydrolysis. These data demonstrate that human keratinocytes possess the capacity for phospholipase C-mediated signal transduction and suggest that this pathway may participate in the regulation of keratinocyte function. Topics: Aluminum; Aluminum Compounds; Blood Physiological Phenomena; Calcium; Cells, Cultured; Diglycerides; Epidermal Cells; Epidermis; Fluorides; Glycerides; Humans; Hydrolysis; Inositol; Inositol Phosphates; Keratins; Phosphatidylinositols; Phospholipids; Stimulation, Chemical | 1989 |