bromochloroacetic-acid and 6-(1-2-3-4-tetrahydro-1-1-4-4-tetramethyl-6-naphthyl)-2-naphthalenecarboxylic-acid

bromochloroacetic-acid has been researched along with 6-(1-2-3-4-tetrahydro-1-1-4-4-tetramethyl-6-naphthyl)-2-naphthalenecarboxylic-acid* in 1 studies

Other Studies

1 other study(ies) available for bromochloroacetic-acid and 6-(1-2-3-4-tetrahydro-1-1-4-4-tetramethyl-6-naphthyl)-2-naphthalenecarboxylic-acid

ArticleYear
Synthesis and pharmacological activity of 6-[(E)-2-(2,6,6-trimethyl-1-cyclohexen-1-yl)ethen-1-yl]- and 6-(1,2,3,4-tetrahydro-1,1,4,4-tetramethyl-6-naphthyl)-2-naphthalenecarboxylic acids.
    Journal of medicinal chemistry, 1983, Volume: 26, Issue:11

    6-[(E)-2-(2,6,6-Trimethyl-1-cyclohexen-1-yl)ethen-1-yl]- and 6-(1,2,3,4-tetrahydro-1,1,4,4-tetramethyl-6-naphthyl)-2-naphthalenecarboxylic acids (4 and 8) have been synthesized and show significant activity in reversing the keratinization process in hamster tracheal organ culture and in inhibiting the induction of ornithine decarboxylase in mouse skin by 12-O-tetradecanoylphorbol-13-acetate, two assays used to measure retinoid activity. The 2-naphthalenecarboxylic acid 8 was more active than 4.

    Topics: Animals; Biological Assay; Cricetinae; Enzyme Induction; Indicators and Reagents; Keratins; Mice; Naphthalenes; Organ Culture Techniques; Ornithine Decarboxylase; Skin; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Trachea

1983