Page last updated: 2024-08-18

bromobenzene and phenobarbital

bromobenzene has been researched along with phenobarbital in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199010 (58.82)18.7374
1990's4 (23.53)18.2507
2000's3 (17.65)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Duffy, EM; Jorgensen, WL1
Caron, G; Ermondi, G1
Abellán Guillén, A; Cordeiro, MN; Garrido Escudero, A; Morales Helguera, A; Pérez-Garrido, A1
Carlson, GP; Day, BJ; DeNicola, DB1
Klaassen, CD; Madhu, C1
Hughes, H; Mitchell, JR; Smith, CV; Tsokos-Kuhn, JO1
Buben, JA; Hanzlik, RP; Narasimhan, N; Weller, PE; Wiley, RA1
Hanzlik, RP1
Billings, RE; Dankovic, D; Seifert, W; Stillwell, WG1
Billings, RE; Dankovic, DA1
Anders, MW; Aniya, Y1
Dent, JG; Sun, JD1
Gillette, JR; Greene, KE; Lau, SS; Monks, TJ1
Lau, SS; Zannoni, VG1
Hesse, S; Mezger, M; Wolff, T1
Brauer, M; Locke, SJ; Lu, W1
Horie, Y; Karbowski, M; Kurono, C; Nishizawa, Y; Soji, T; Wakabayashi, T1

Other Studies

17 other study(ies) available for bromobenzene and phenobarbital

ArticleYear
Prediction of drug solubility from Monte Carlo simulations.
    Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11

    Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility

2000
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Convenient QSAR model for predicting the complexation of structurally diverse compounds with beta-cyclodextrins.
    Bioorganic & medicinal chemistry, 2009, Jan-15, Volume: 17, Issue:2

    Topics: beta-Cyclodextrins; Hydrophobic and Hydrophilic Interactions; Organic Chemicals; Quantitative Structure-Activity Relationship

2009
Potentiation of bromobenzene-induced pneumotoxicity by phenobarbital as determined by bronchoalveolar lavage fluid analysis.
    Drug and chemical toxicology, 1992, Volume: 15, Issue:1

    Topics: Analysis of Variance; Animals; Bromobenzenes; Bronchoalveolar Lavage Fluid; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Interactions; gamma-Glutamyltransferase; L-Lactate Dehydrogenase; Liver; Lung; Male; Microsomes, Liver; Oxidoreductases; Phenobarbital; Rats; Rats, Inbred Strains

1992
Bromobenzene-glutathione excretion into bile reflects toxic activation of bromobenzene in rats.
    Toxicology letters, 1992, Volume: 60, Issue:2

    Topics: Animals; Bile; Biotransformation; Bromobenzenes; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Glutathione; Injections, Intraperitoneal; Liver; Male; Methylcholanthrene; Phenobarbital; Polysorbates; Rats

1992
Alkylating toxins and the liver plasma membrane calcium pump/calcium atpase.
    Advances in experimental medicine and biology, 1988, Volume: 232

    Topics: Acetaminophen; Animals; Bromobenzenes; Calcium; Calcium-Transporting ATPases; Carbon Tetrachloride; Cell Membrane; Homeostasis; Kinetics; Liver; Male; Methylcholanthrene; Phenobarbital; Rats; Rats, Inbred Strains

1988
Microsomal metabolism and covalent binding of [3H/14C]-bromobenzene. Evidence for quinones as reactive metabolites.
    Xenobiotica; the fate of foreign compounds in biological systems, 1988, Volume: 18, Issue:5

    Topics: Animals; Bromobenzenes; Male; Microsomes, Liver; Phenobarbital; Quinones; Rats; Rats, Inbred Strains

1988
Chemistry of covalent binding: studies with bromobenzene and thiobenzamide.
    Advances in experimental medicine and biology, 1986, Volume: 197

    Topics: Amides; Animals; Biotransformation; Bromobenzenes; Carbon Radioisotopes; Kidney; Liver; Lung; Male; Microsomes, Liver; Organ Specificity; Phenobarbital; Rats; Rats, Inbred Strains; Thioamides; Tritium

1986
Bromobenzene metabolism in isolated rat hepatocytes. 18O2 incorporation studies.
    Molecular pharmacology, 1985, Volume: 27, Issue:2

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Bromobenzenes; Catechols; In Vitro Techniques; Liver; Male; Oxygen Isotopes; Phenobarbital; Rats; Rats, Inbred Strains

1985
The role of 4-bromophenol and 4-bromocatechol in bromobenzene covalent binding and toxicity in isolated rat hepatocytes.
    Toxicology and applied pharmacology, 1985, Jun-30, Volume: 79, Issue:2

    Topics: Animals; Bromobenzenes; Carbon Radioisotopes; Catechols; Cytotoxins; Glutathione; Intracellular Fluid; L-Lactate Dehydrogenase; Liver; Male; Phenobarbital; Phenols; Rats; Rats, Inbred Strains

1985
Alteration of hepatic glutathione S-transferases and release into serum after treatment with bromobenzene, carbon tetrachloride, or N-nitrosodimethylamine.
    Biochemical pharmacology, 1985, Dec-15, Volume: 34, Issue:24

    Topics: Animals; Bromobenzenes; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; Cytosol; Dimethylnitrosamine; Ethanol; Glutathione Transferase; Liver; Male; Phenobarbital; Rats; Rats, Inbred Strains

1985
Macromolecular weight specificity in covalent binding of bromobenzene.
    Toxicology and applied pharmacology, 1984, Volume: 76, Issue:2

    Topics: Animals; Bromobenzenes; Carbon Radioisotopes; Liver; Macromolecular Substances; Male; Methylcholanthrene; Molecular Weight; Phenobarbital; Phenylmethylsulfonyl Fluoride; Proteins; Rats; Rats, Inbred F344

1984
Detection and half-life of bromobenzene-3,4-oxide in blood.
    Xenobiotica; the fate of foreign compounds in biological systems, 1984, Volume: 14, Issue:7

    Topics: Animals; Bromobenzenes; Half-Life; Male; Maleates; Phenobarbital; Rats; Rats, Inbred Strains

1984
Bromobenzene metabolism in the rabbit: specific forms of cytochrome P-450 involved in 2,3- and 3,4-epoxidation.
    Molecular pharmacology, 1981, Volume: 20, Issue:1

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Bromobenzenes; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Cytochromes; In Vitro Techniques; Microsomes, Liver; Phenobarbital; Phenols; Rabbits

1981
Formation of irreversible protein-binding metabolites during microsomal metabolism of 14C-bromobenzene and 14C-bromophenol.
    Advances in experimental medicine and biology, 1981, Volume: 136 Pt A

    Topics: Animals; Biotransformation; Bromobenzenes; Carbon Radioisotopes; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Phenols; Protein Binding; Proteins; Rats; Rats, Inbred Strains

1981
In vivo and in vitro 31P magnetic resonance spectroscopic studies of the hepatic response of healthy rats and rats with acute hepatic damage to fructose loading.
    Magnetic resonance in medicine, 1994, Volume: 31, Issue:5

    Topics: Adenosine Triphosphate; Animals; Antioxidants; Bromobenzenes; Carbon Tetrachloride; Chromans; Fructose; Fructose-Bisphosphate Aldolase; Fructosephosphates; Glucose-6-Phosphate; Glucosephosphates; Glycerophosphates; Hydrogen-Ion Concentration; In Vitro Techniques; Liver; Magnetic Resonance Spectroscopy; Male; Organophosphates; Phenobarbital; Phosphorus; Phosphorylcholine; Rats; Rats, Wistar; Time Factors; Vitamin E

1994
Induction of megamitochondria by some chemicals inducing oxidative stress in primary cultured rat hepatocytes.
    Biochimica et biophysica acta, 1997, Nov-30, Volume: 1349, Issue:3

    Topics: Animals; Bromobenzenes; Cell Survival; Cells, Cultured; Cycloheximide; Cytochrome P-450 Enzyme System; Erythromycin; Free Radicals; Hydrazines; Hydrogen Peroxide; Lipid Peroxides; Liver; Male; Malondialdehyde; Microscopy, Confocal; Microscopy, Electron; Mitochondria, Liver; Oxidative Stress; Phenobarbital; Protein Synthesis Inhibitors; Rats; Rats, Wistar

1997