Page last updated: 2024-08-18

bromobenzene and acetaminophen

bromobenzene has been researched along with acetaminophen in 25 studies

Research

Studies (25)

Timeframe	Studies, this research(%)	All Research%
pre-1990	10 (40.00)	18.7374
1990's	4 (16.00)	18.2507
2000's	7 (28.00)	29.6817
2010's	2 (8.00)	24.3611
2020's	2 (8.00)	2.80

Authors

Authors	Studies
Duffy, EM; Jorgensen, WL	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Piotrowski, JK; Swietlicka, EA; Szymańska, JA	1
Moore, L; Wright, PB	1
Hughes, H; Mitchell, JR; Smith, CV; Tsokos-Kuhn, JO	1
Lau, SS; Monks, TJ	1
Farber, JL	2
Hook, JB; Smith, JH	1
McMillin-Wood, JB; Mitchell, JR; Todd, EL; Tsokos-Kuhn, JO	1
Dent, JG; Leonard, TB	1
Hook, JB; Newton, JF; Rush, GF; Smith, JH	1
Cameron, RG; Farber, E; Hayes, MA; Roberts, E; Roomi, MW; Safe, SH	1
Hughes, H; Mitchell, JR; Smith, CV	1
Cohen, SD; Khairallah, EA; Manautou, JE	1
Roberts, SM; Salminen, WF; Voellmy, R	1
Apte, UM; Bucci, TJ; Manautou, JE; Mehendale, HM; Ronis, MJ; Shankar, K; Vaidya, VS	1
Berson, A; Descatoire, V; Feldmann, G; Grodet, A; Pessayre, D; Thénot, JP; Tinel, M; Vadrot, N	1
Ali, S; Pawa, S	1
Kato, H; Katoh, M; Minami, K; Nakajima, M; Narahara, M; Saito, T; Sugiyama, H; Tomita, H; Yokoi, T	1
Horbach, GJ; Kloks, CP; Mellema, JR; Ploemen, JP; Schoonen, WG; Smit, MJ; Tas, AC; van Nesselrooij, JH; Vogels, JT; Zandberg, P; Zuylen, CT	1
Benson, CA; Goldring, CE; Kitteringham, NR; Metcalfe, PN; Park, BK; Randle, LE; Williams, DP	1
Estes, SK; O'Brien, TP; Oyama, T; Pannala, VR; Printz, RL; Rahim, M; Reifman, J; Shiota, C; Shiota, M; Trenary, I; Wallqvist, A; Young, JD	1
Estes, SK; O'Brien, TP; Pannala, VR; Printz, RL; Rahim, M; Reifman, J; Shiota, C; Shiota, M; Trenary, I; Wallqvist, A; Young, JD	1

Reviews

4 review(s) available for bromobenzene and acetaminophen

Article	Year
Reactive intermediates and their toxicological significance. Toxicology, 1988, Nov-14, Volume: 52, Issue:1-2 Topics: Acetaminophen; Animals; Biotransformation; Bromobenzenes; Carbon Tetrachloride; Glucuronates; Glutathione; Humans; Lipid Peroxidation; Sulfates; Xenobiotics	1988
Xenobiotics, drug metabolism, and liver injury. Monographs in pathology, 1987, Issue:28 Topics: Acetaminophen; Animals; Bromobenzenes; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Glutathione; Humans; Inactivation, Metabolic; Liver; Mixed Function Oxygenases; Oxidation-Reduction	1987
Biochemical mechanisms of nephrotoxicity. Transplantation proceedings, 1985, Volume: 17, Issue:4 Suppl 1 Topics: Acetaminophen; Aminoglycosides; Animals; Biotransformation; Bromobenzenes; Cephaloridine; Chloroform; Female; Kidney; Kidney Diseases; Liver; Male; Organ Specificity	1985
Chemically induced nephrotoxicity: role of metabolic activation. Critical reviews in toxicology, 1984, Volume: 13, Issue:2 Topics: Acetaminophen; Animals; Antifungal Agents; Antinematodal Agents; Biotransformation; Bromobenzenes; Butadienes; Carbon Tetrachloride; Cephaloridine; Chloroform; Ethylene Dibromide; Female; Humans; Inactivation, Metabolic; Kidney; Kidney Diseases; Lethal Dose 50; Male; Organophosphates; Propane; Rats; Terpenes	1984

Other Studies

21 other study(ies) available for bromobenzene and acetaminophen

Article	Year
Prediction of drug solubility from Monte Carlo simulations. Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11 Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility	2000
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Protective effect of zinc in the hepatotoxicity of bromobenzene and acetaminophen. Toxicology, 1991, Feb-11, Volume: 66, Issue:1 Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Bromobenzenes; Glutathione; Injections, Intraperitoneal; L-Iditol 2-Dehydrogenase; Liver; Male; Metallothionein; Mice; Mice, Inbred BALB C; Zinc	1991
Potentiation of the toxicity of model hepatotoxicants by acetaminophen. Toxicology and applied pharmacology, 1991, Jun-15, Volume: 109, Issue:2 Topics: 1-Propanol; Acetaminophen; Alanine Transaminase; Animals; Bromobenzenes; Carbon Tetrachloride; Dichloroethylenes; Drug Synergism; Liver; Male; Models, Biological; Propanols; Rats; Rats, Inbred Strains; Thioacetamide; Time Factors	1991
Alkylating toxins and the liver plasma membrane calcium pump/calcium atpase. Advances in experimental medicine and biology, 1988, Volume: 232 Topics: Acetaminophen; Animals; Bromobenzenes; Calcium; Calcium-Transporting ATPases; Carbon Tetrachloride; Cell Membrane; Homeostasis; Kinetics; Liver; Male; Methylcholanthrene; Phenobarbital; Rats; Rats, Inbred Strains	1988
Biochemical mechanisms of toxic cell injury. Klinische Wochenschrift, 1986, Volume: 64 Suppl 7 Topics: Acetaminophen; Animals; Bromobenzenes; Cell Survival; Free Radicals; Lipid Peroxides; Liver; Mixed Function Oxygenases; Oxygen	1986
ATP-dependent calcium uptake by rat liver plasma membrane vesicles. Effect of alkylating hepatotoxins in vivo. Molecular pharmacology, 1985, Volume: 28, Issue:1 Topics: Acetaminophen; Adenosine Triphosphate; Alkylating Agents; Animals; Biological Transport, Active; Bromobenzenes; Calcium; Carbon Tetrachloride Poisoning; Cell Membrane; Cell-Free System; Glutathione; Liver; Male; Microsomes, Liver; Mitochondria, Liver; Rats; Rats, Inbred Strains	1985
Effects of H2 receptor antagonists on the hepatotoxicity of various chemicals. Research communications in chemical pathology and pharmacology, 1984, Volume: 44, Issue:3 Topics: 1-Propanol; Acetaminophen; Animals; Bromobenzenes; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chloroform; Cimetidine; Drug Antagonism; Drug Synergism; Histamine H2 Antagonists; Imidazoles; Liver; Male; Propanols; Pyrimidinones; Ranitidine; Rats; Rats, Inbred F344	1984
Comparative influences of different PB-type and 3-MC-type polychlorinated biphenyl-induced phenotypes on cytocidal hepatotoxicity of bromobenzene and acetaminophen. Toxicology and applied pharmacology, 1984, Volume: 76, Issue:1 Topics: Acetaminophen; Animals; Bromobenzenes; Cells, Cultured; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Interactions; L-Lactate Dehydrogenase; Liver; Male; Polychlorinated Biphenyls; Rats; Rats, Inbred F344	1984
Free radicals in vivo. Covalent binding to lipids. Molecular pharmacology, 1984, Volume: 26, Issue:1 Topics: Acetaminophen; Animals; Bromobenzenes; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemistry; Dimethylnitrosamine; Free Radicals; Furans; Furosemide; Lipid Metabolism; Liver; Male; Mice; Mice, Inbred ICR; Rats; Rats, Inbred Strains	1984
Evidence for common binding of acetaminophen and bromobenzene to the 58-kDa acetaminophen-binding protein. Journal of toxicology and environmental health, 1995, Volume: 46, Issue:3 Topics: Acetaminophen; Animals; Bromobenzenes; Carrier Proteins; Liver; Male; Mice; Mice, Inbred ICR; Molecular Weight; Selenium-Binding Proteins	1995
Protection against hepatotoxicity by a single dose of amphetamine: the potential role of heat shock protein induction. Toxicology and applied pharmacology, 1997, Volume: 147, Issue:2 Topics: Acetaminophen; Amphetamine; Animals; Bromobenzenes; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cocaine; Fever; Heat-Shock Proteins; Hyperthermia, Induced; Immunohistochemistry; Liver; Male; Mice; Mice, Inbred ICR	1997
Type 1 diabetic mice are protected from acetaminophen hepatotoxicity. Toxicological sciences : an official journal of the Society of Toxicology, 2003, Volume: 73, Issue:2 Topics: Acetaminophen; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Aspartate Aminotransferases; Bromobenzenes; Carbon Tetrachloride; Cell Division; Chemical and Drug Induced Liver Injury; Colchicine; Diabetes Mellitus, Experimental; Disease Models, Animal; DNA; Drug Therapy, Combination; Liver; Liver Regeneration; Male; Mice; Microsomes, Liver; Proliferating Cell Nuclear Antigen	2003
Subliminal Fas stimulation increases the hepatotoxicity of acetaminophen and bromobenzene in mice. Hepatology (Baltimore, Md.), 2004, Volume: 39, Issue:3 Topics: Acetaminophen; Adenosine Triphosphate; Analgesics, Non-Narcotic; Animals; Bromobenzenes; Caspase 3; Caspases; Dose-Response Relationship, Drug; Drug Synergism; fas Receptor; Glutamate-Cysteine Ligase; Glutathione; Liver; Liver Diseases; Male; Mice; Nitric Oxide Synthase; Nitric Oxide Synthase Type II	2004
Liver necrosis and fulminant hepatic failure in rats: protection by oxyanionic form of tungsten. Biochimica et biophysica acta, 2004, Apr-05, Volume: 1688, Issue:3 Topics: Acetaminophen; Alkaline Phosphatase; Allopurinol; Animals; Bromobenzenes; Carbon Tetrachloride Poisoning; Chloroform; Dimethyl Sulfoxide; Female; Lethal Dose 50; Liver; Liver Failure; Necrosis; Oxidative Stress; Rats; Rats, Wistar; Thioacetamide; Transaminases; Tungsten Compounds	2004
Relationship between hepatic gene expression profiles and hepatotoxicity in five typical hepatotoxicant-administered rats. Toxicological sciences : an official journal of the Society of Toxicology, 2005, Volume: 87, Issue:1 Topics: Acetaminophen; Alkaline Phosphatase; Animals; Bromobenzenes; Carbon Tetrachloride; Dimethylnitrosamine; Gene Expression Profiling; L-Lactate Dehydrogenase; Liver; Male; Rats; Rats, Sprague-Dawley; Thioacetamide	2005
Sensitivity of (1)H NMR analysis of rat urine in relation to toxicometabonomics. Part I: dose-dependent toxic effects of bromobenzene and paracetamol. Toxicological sciences : an official journal of the Society of Toxicology, 2007, Volume: 98, Issue:1 Topics: Acetaminophen; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Aspartate Aminotransferases; Bromobenzenes; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Kidney; Liver; Magnetic Resonance Spectroscopy; Necrosis; Principal Component Analysis; Rats	2007
Investigation of the effect of a panel of model hepatotoxins on the Nrf2-Keap1 defence response pathway in CD-1 mice. Toxicology, 2008, Jan-20, Volume: 243, Issue:3 Topics: Acetaminophen; Adaptor Proteins, Signal Transducing; Alanine Transaminase; Analysis of Variance; Animals; Blotting, Western; Bromobenzenes; Carbon Tetrachloride; Cell Nucleus; Cytoskeletal Proteins; Furosemide; Glutamate-Cysteine Ligase; Glutathione; Heme Oxygenase-1; Injections, Intraperitoneal; Kelch-Like ECH-Associated Protein 1; Liver; Male; Mice; Molecular Structure; NF-E2-Related Factor 2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Xenobiotics	2008
Mechanism-based identification of plasma metabolites associated with liver toxicity. Toxicology, 2020, Volume: 441 Topics: Acetaminophen; Animals; Biomarkers; Bromobenzenes; Chemical and Drug Induced Liver Injury; Gene Expression Profiling; Liver; Male; Metabolomics; Rats, Sprague-Dawley	2020
Toxicant-Induced Metabolic Alterations in Lipid and Amino Acid Pathways Are Predictive of Acute Liver Toxicity in Rats. International journal of molecular sciences, 2020, Nov-04, Volume: 21, Issue:21 Topics: Acetaminophen; Acute Disease; Amino Acids; Animals; Biomarkers; Bromobenzenes; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Gene Expression Profiling; Hazardous Substances; Hepatocytes; Lipid Metabolism; Liver; Male; Metabolic Networks and Pathways; Metabolome; Metabolomics; Prognosis; Rats; Rats, Sprague-Dawley; Transcriptome	2020