Page last updated: 2024-08-23

brofaromine and piperidines

brofaromine has been researched along with piperidines in 112 studies

Research

Studies (112)

TimeframeStudies, this research(%)All Research%
pre-199029 (25.89)18.7374
1990's78 (69.64)18.2507
2000's5 (4.46)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alvarez, E; Artigas, F; Celada, P; Pérez, J1
Stöcklin, K; Waldmeier, PC3
Bianchi, M; Mantegazza, P; Panerai, AE1
Antonin, KH; Bieck, PR; Gleiter, CH; Mühlbauer, B; Nilsson, E1
Möller, HJ; Volz, HP2
Garcia-Borreguero, D; Holsboer, F; Krieg, JC; Lauer, CJ; Ozdaglar, A; Wiedemann, K1
Feldtrauer, JJ; Graf, T; Howald, H; Waldmeier, PC1
Antonin, KH; Bieck, PR; Schmidt, E1
Bakish, D; Bradwejn, J; Chouinard, G; Kennedy, SH; Kukha-Mohamad, SA; Kutcher, SP; Nair, NP; Remick, RA; Saxena, BM; Sharma, V3
Boulton, AA; Dyck, LE1
den Boer, JA; van Vliet, IM; Westenberg, HG2
Delcker, A; Gaertner, HJ1
Möller, HJ; Waldmeier, P; Wendt, G1
Fritze, J; Lanczik, M; Pfüller, H; Riederer, P; Sofic, E1
Anderson, MC; Tipton, KF; Waldmeier, PC1
Haffmans, PM; Hoencamp, E1
Becker, T; Beckmann, H; Classen, W; Laux, G; Lesch, KP; Riederer, P; Sofic, E; Struck, M1
Becker, T; Bieck, P; Fritze, J; Laux, G; Riederer, P; Sofic, E; Ziegler, V1
Davies, M; Fletcher, PJ1
Klimek, V; Maj, J; Nowak, G; Zak, J1
Becker, T; Fritze, J; Laux, G; Riederer, P; Ziegler, V1
Fletcher, PJ; Yu, PH1
Da Prada, M; Keller, HH; Kettler, R1
Bieck, PR1
Delini-Stula, A; Heath, WR; Schiwy, W1
Burkard, WP; Da Prada, M; Haefely, WE; Keller, HH; Kettler, R1
Möller, HJ; Wendt, G1
Degen, PH; Keller, B; Schneider, W1
Antonin, KH; Bieck, PR2
Antonin, KH; Bieck, PR; Firkusny, L; Nilsson, E; Schick, C; Schulz, R; Schwenk, M; Wollmann, H1
Dostert, P; Strolin Benedetti, M1
Benkert, O; Holsboer, F; Steiger, A2
Marek, GJ; Seiden, LS1
Cesura, AM; Da Prada, M; Kettler, R; Richards, JG1
Finberg, JP; Youdim, MB1
Horne, C; Mutschler, E1
Antonin, KH; Balon, R; Bieck, PR; Oxenkrug, G1
Benkert, O; Demisch, L; Gerken, A; Holsboer, F; Steiger, A1
Pare, CM1
Da Prada, M; Keller, G; Keller, HH; Kettler, R1
Waldmeier, PC2
Baumann, PA; Bernasconi, R; Buech, O; Delini-Stula, A; Felner, AE; Sigg, K; Waldmeier, PC1
Baumann, PA; Waldmeier, PC1
Feldtrauer, JJ; Paul, E; Stoecklin, K; Waldmeier, PC1
Antonin, KH; Bieck, P; Feldtrauer, JJ; Grunenwald, C; Lauber, J; Paul, E; Waldmeier, PC1
Felner, AE; Tipton, KF; Waldmeier, PC1
Antonin, KH; Bieck, P; Jedrychowski, M1
Boulton, AA; D'Souza, J; Davis, BA; Durden, DA; Goldbloom, DS; Kennedy, SH2
Brown, GM; d'Souza, J; Davis, BA; Ford, CG; Kennedy, SH1
Artigas, F; Bel, N1
Bédard, M; D'Souza, J; Darzins, PJ; Guyatt, GH; Molloy, DW; Mondadori, C; Standish, T1
Möller, HJ; Müller, H; Volz, HP2
den Boer, JA; Slaap, BR; van Vliet, IM; Westenberg, HG4
Gimbrett, R; Priest, RG; Roberts, M; Steinert, J1
Finberg, JP1
Antonin, KH; Bieck, PR; Gleiter, CH; Mühlbauer, B; Nilsson, E; Schulz, RM1
Artigas, F; Bel, N; Celada, P1
O'Hanlon, JF; Ramaekers, JG; van Veggel, LM1
Bellaire, J; Heimann, H; Laux, G; Möller, HJ; Volz, HP1
Dijken, WA; Duivenvoorden, H; Haffmans, PM; Hoencamp, E; Knegtering, H1
Faltus, F; Magyar, I; Möller, HJ; Volz, HP1
Dijken, WA; Haffmans, PM; Hoencamp, E; Hoogduin, CA; Nolen, WA; van Dyck, R1
Katz, RJ; Rosenthal, M1
Fallon, BA; Feerick, J; Liebowitz, MR; Marshall, RD; Schneier, FR1
D'Souza, JD; Davis, C; Goldbloom, DS; Kennedy, SH; Lofchy, J; Ralevski, E1
Bakish, D1
Verhoeven, WM1
Antonin, KH; Bieck, PR; Feifel, N; Fuchs, L; Gleiter, CH; Jedrychowski, M; Kucher, K; Schmidt, E1
Finberg, JP; Lavian, G; Youdim, MB1
Bittiger, H; Glatt, A; Jaekel, J; Waldmeier, PC1
Bouvy, PF; Haffmans, PM; Hoencamp, E; Nolen, WA1
Bakish, D; Bowen, R; D'Souza, J; Saxena, BM1
Hoffmans, J; Knegtering, R1
Bouvy, PF; Duivenvoorden, HJ; Haffmans, PM; Nolen, WA1
Boulton, AA; Durden, DA; Dyck, LE1
Borroni, E; Cesura, AM; Colzi, A; D'Agostini, F; Da Prada, M1
Cardot, JM; Czendlik, C; Degen, PH; Dieterle, W1
Bieck, PR; Feifel, N; Jedrychowski, M; Schmidt, EK1
Fahlén, T1
Möller, HJ; Müller, H; Preussler, B; Sturm, Y; Volz, HP1
Borg, K; Fahlén, T; Humble, M; Nilsson, HL; Pauli, U1
Baker, DG; Diamond, BI; Gillette, G; Hamner, M; Katzelnick, D; Keller, T; Mellman, TA; Pontius, E; Rosenthal, M; Tucker, P1
Bieck, PR; Gleiter, CH; Herrmann, WM; Jobert, M; Reimann, IW; Turri, M1
Ametamey, SM; Antonini, A; Beer, HF; Guenther, I; Leenders, KL; Schubiger, PA; Waldmeier, PC1
Antonin, KH; Bergmann, W; Bieck, P; Degel, F; Fuchs, L; Platt, D; Zeeh, J1
Artigas, F; Bel, N; Casanovas, JM; Romero, L1
Gleiter, CH; Möller, HJ; Struck, M; Volz, HP; Waldmeier, PC1
Gleiter, CH; Möller, HJ; Volz, HP1
Stein, MB1
Dresse, A; Gerardy, J1
Franke, L; Schewe, HJ; Uebelhack, R1
Lotufo-Neto, F; Thase, ME; Trivedi, M1
Haffmans, PM; Vos, MS1
Allison, K; Baker, GB; Greenshaw, AJ; Holt, A; Urichuk, LJ1
Schneier, FR1
Connor, KM; Crockett, B; Davidson, JR; Hidalgo, RB; Katz, RJ; Malik, M1
Blanco, C; Blanco-Jerez, CR; Liebowitz, MR; Marshall, RD; Sánchez-Lacay, A; Schmidt, A; Schneier, FR1
Agostinelli, E; Artico, M; Befani, O; Cirilli, R; Costi, R; Di Santo, R; Ferretti, R; Gallinella, B; La Torre, F; Meninno, T; Palmegiani, P; Roux, A; Turini, P1

Reviews

16 review(s) available for brofaromine and piperidines

ArticleYear
Brofaromine--a selective, reversible, and short-acting MAO-A inhibitor: review of the pharmacological and clinical findings.
    Pharmacopsychiatry, 1991, Volume: 24, Issue:2

    Topics: Animals; Humans; Monoamine Oxidase Inhibitors; Piperidines

1991
Preclinical profiles of the novel reversible MAO-A inhibitors, moclobemide and brofaromine, in comparison with irreversible MAO inhibitors.
    Journal of neural transmission. Supplementum, 1989, Volume: 28

    Topics: Animals; Benzamides; Brain Chemistry; Humans; Moclobemide; Monoamine Oxidase Inhibitors; Piperidines

1989
[Brofaromine--a selective, reversible and short-acting MAO-A inhibitor].
    Psychiatrische Praxis, 1989, Volume: 16 Suppl 1

    Topics: Antidepressive Agents; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Humans; Piperidines

1989
Overview of the present state of MAO inhibitors.
    Journal of neural transmission. Supplementum, 1987, Volume: 23

    Topics: Animals; Benzamides; Humans; Hydrazines; Isoquinolines; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Parkinson Disease; Phenethylamines; Piperidines; Selegiline; Structure-Activity Relationship

1987
New pharmacological developments in antidepressants.
    Psychopathology, 1986, Volume: 19 Suppl 2

    Topics: Amitriptyline; Drug Interactions; Humans; Hypertension; Monoamine Oxidase Inhibitors; Piperidines; Tyramine

1986
Pharmacology of reversible and selective inhibitors of monoamine oxidase type A.
    Acta psychiatrica Scandinavica. Supplementum, 1995, Volume: 386

    Topics: Animals; Benzamides; Clorgyline; Dopamine; Moclobemide; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Norepinephrine; Piperidines; Rats; Serotonin; Sympathetic Nervous System; Tyramine

1995
Medication therapy for social phobia.
    The Journal of clinical psychiatry, 1994, Volume: 55 Suppl

    Topics: Benzamides; Benzodiazepines; Clinical Trials as Topic; Cognitive Behavioral Therapy; Combined Modality Therapy; Comorbidity; Fluoxetine; Humans; Moclobemide; Monoamine Oxidase Inhibitors; Phenelzine; Phobic Disorders; Piperidines; Selective Serotonin Reuptake Inhibitors; Treatment Outcome

1994
Brofaromine in endogenous depression.
    Progress in neuro-psychopharmacology & biological psychiatry, 1994, Volume: 18, Issue:2

    Topics: Antidepressive Agents; Depressive Disorder; Humans; Monoamine Oxidase Inhibitors; Piperidines

1994
Brofaromine: a monoamine oxidase-A and serotonin uptake inhibitor.
    Clinical neuropharmacology, 1993, Volume: 16 Suppl 2

    Topics: Animals; Humans; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Piperidines; Selective Serotonin Reuptake Inhibitors

1993
Reversible monoamine oxidase-A inhibitors in resistant major depression.
    Clinical neuropharmacology, 1993, Volume: 16 Suppl 2

    Topics: Antidepressive Agents; Depressive Disorder; Drug Resistance; Humans; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Piperidines

1993
Newer aspects of the reversible inhibitor of MAO-A and serotonin reuptake, brofaromine.
    Progress in neuro-psychopharmacology & biological psychiatry, 1993, Volume: 17, Issue:2

    Topics: Animals; Humans; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Piperidines; Selective Serotonin Reuptake Inhibitors; Tyramine

1993
Brofaromine--a review of its pharmacological properties and therapeutic use.
    Journal of neural transmission (Vienna, Austria : 1996), 1996, Volume: 103, Issue:1-2

    Topics: Animals; Brain Chemistry; Depressive Disorder; Humans; Monoamine Oxidase Inhibitors; Piperidines

1996
Medication treatments for panic disorder and social phobia.
    Depression and anxiety, 1998, Volume: 7, Issue:3

    Topics: Antidepressive Agents, Tricyclic; Benzamides; Benzodiazepines; Citalopram; Clinical Trials as Topic; Clomipramine; Clonazepam; Dose-Response Relationship, Drug; Female; Humans; Male; Moclobemide; Monoamine Oxidase Inhibitors; Panic Disorder; Paroxetine; Piperidines; Recurrence; Selective Serotonin Reuptake Inhibitors; Social Behavior Disorders

1998
Meta-analysis of the reversible inhibitors of monoamine oxidase type A moclobemide and brofaromine for the treatment of depression.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1999, Volume: 20, Issue:3

    Topics: Benzamides; Controlled Clinical Trials as Topic; Depression; Humans; Moclobemide; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Piperidines; Treatment Outcome

1999
Treatment of social phobia with antidepressants.
    The Journal of clinical psychiatry, 2001, Volume: 62 Suppl 1

    Topics: Antidepressive Agents; Controlled Clinical Trials as Topic; Drug Approval; Humans; Moclobemide; Monoamine Oxidase Inhibitors; Paroxetine; Phenelzine; Phobic Disorders; Piperidines; Selective Serotonin Reuptake Inhibitors; Treatment Outcome; United States

2001
Pharmacological treatment of social anxiety disorder: a meta-analysis.
    Depression and anxiety, 2003, Volume: 18, Issue:1

    Topics: Acetates; Amines; Anti-Anxiety Agents; Antidepressive Agents; Antimanic Agents; Anxiety Disorders; Calcium Channel Blockers; Clonazepam; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Female; GABA Modulators; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Monoamine Oxidase Inhibitors; Phenelzine; Phobic Disorders; Piperidines; Selective Serotonin Reuptake Inhibitors; Treatment Outcome

2003

Trials

41 trial(s) available for brofaromine and piperidines

ArticleYear
Brofaromine in major depressed patients: a controlled clinical trial versus imipramine and open follow-up of up to one year.
    Journal of affective disorders, 1992, Volume: 26, Issue:3

    Topics: Adult; Depressive Disorder; Double-Blind Method; Female; Follow-Up Studies; Humans; Imipramine; Long-Term Care; Male; Middle Aged; Monoamine Oxidase Inhibitors; Personality Inventory; Piperidines

1992
Efficacy and safety of brofaromine in depression: a Canadian multicenter placebo controlled trial and a review of comparative controlled studies.
    Clinical neuropharmacology, 1992, Volume: 15 Suppl 1 Pt A

    Topics: Depressive Disorder; Humans; Monoamine Oxidase Inhibitors; Piperidines; Psychiatric Status Rating Scales; Single-Blind Method

1992
Psychopharmacological treatment of social phobia: clinical and biochemical effects of brofaromine, a selective MAO-A inhibitor.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1992, Volume: 2, Issue:1

    Topics: Adult; Blood Pressure; Double-Blind Method; Female; Humans; Hydrocortisone; Male; Melatonin; Methoxyhydroxyphenylglycol; Monoamine Oxidase Inhibitors; Phobic Disorders; Piperidines; Psychiatric Status Rating Scales

1992
Adrenergic-cholinergic imbalances: the physostigmine-syndrome is not antagonized by the MAO-A inhibitor brofaromine.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1990, Volume: 1, Issue:1

    Topics: Adult; Blood Glucose; Depression; Double-Blind Method; Humans; Hydrocortisone; Male; Monoamine Oxidase Inhibitors; Parasympathetic Nervous System; Physostigmine; Piperidines; Scopolamine; Sympathetic Nervous System; Synaptic Transmission

1990
Clinical, biochemical and psychometric findings with the new MAO-A-inhibitors moclobemide and brofaromine in patients with major depressive disorder.
    Journal of neural transmission. Supplementum, 1990, Volume: 32

    Topics: Benzamides; Catecholamines; Depressive Disorder; Double-Blind Method; Female; Humans; Male; Middle Aged; Moclobemide; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Piperidines; Psychiatric Status Rating Scales

1990
Therapeutic and side-effect profile of a selective and reversible MAO-A inhibitor, brofaromine. Results of dose-finding trials in depressed patients.
    Journal of neural transmission. Supplementum, 1989, Volume: 28

    Topics: Adult; Aged; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Female; Humans; Male; Middle Aged; Monoamine Oxidase Inhibitors; Nomifensine; Piperidines; Psychiatric Status Rating Scales; Random Allocation; Tranylcypromine

1989
[Brofaromine--a selective, reversible and short-acting MAO-A inhibitor].
    Psychiatrische Praxis, 1989, Volume: 16 Suppl 1

    Topics: Antidepressive Agents; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Humans; Piperidines

1989
Oral tyramine pressor test and the safety of monoamine oxidase inhibitor drugs: comparison of brofaromine and tranylcypromine in healthy subjects.
    Journal of clinical psychopharmacology, 1988, Volume: 8, Issue:4

    Topics: Adolescent; Adult; Antidotes; Blood Pressure; Dose-Response Relationship, Drug; Female; Heart Rate; Humans; Male; Monoamine Oxidase Inhibitors; Phentolamine; Piperidines; Tranylcypromine; Tyramine

1988
The effect of the MAO-A selective inhibitor brofaromine on the plasma and urine concentrations of some biogenic amines and their acidic metabolites in bulimia nervosa.
    Progress in neuro-psychopharmacology & biological psychiatry, 1993, Volume: 17, Issue:5

    Topics: Biogenic Amines; Bulimia; Double-Blind Method; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Piperidines; Tryptamines; Vanilmandelic Acid

1993
Effects of chronic brofaromine administration on biogenic amines including sulphatoxymelatonin and acid metabolites in patients with bulimia nervosa.
    Neurochemical research, 1993, Volume: 18, Issue:12

    Topics: Adolescent; Adult; Biogenic Amines; Bulimia; Female; Homovanillic Acid; Humans; Hydrogen-Ion Concentration; Hydroxyindoleacetic Acid; Melatonin; Monoamine Oxidase Inhibitors; Piperidines; Tryptamines; Vanilmandelic Acid

1993
Clinical trials in cognitively impaired older adults: home versus clinic assessments.
    Journal of the American Geriatrics Society, 1995, Volume: 43, Issue:10

    Topics: Aged; Alzheimer Disease; Clinical Trials as Topic; Female; Geriatric Assessment; Home Care Services; Humans; Male; Monoamine Oxidase Inhibitors; Outpatient Clinics, Hospital; Patient Dropouts; Piperidines; Reproducibility of Results; Selection Bias; Survival Analysis

1995
Are there any differences in the safety and efficacy of brofaromine and imipramine between non-elderly and elderly patients with major depression?
    Neuropsychobiology, 1995, Volume: 32, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Antidepressive Agents, Tricyclic; Depressive Disorder; Double-Blind Method; Female; Humans; Imipramine; Male; Middle Aged; Monoamine Oxidase Inhibitors; Piperidines; Psychiatric Status Rating Scales

1995
Phobic symptoms as predictors of nonresponse to drug therapy in panic disorder patients (a preliminary report).
    Journal of affective disorders, 1995, Jan-11, Volume: 33, Issue:1

    Topics: Adult; Agoraphobia; Double-Blind Method; Female; Fluvoxamine; Humans; Male; Middle Aged; Monoamine Oxidase Inhibitors; Panic; Panic Disorder; Personality Inventory; Phobic Disorders; Piperidines; Prognosis; Treatment Outcome

1995
A Canadian multicentre placebo-controlled study of a fixed dose of brofaromine, a reversible selective MAO-A inhibitor, in the treatment of major depression.
    Journal of affective disorders, 1994, Volume: 32, Issue:2

    Topics: Adolescent; Adult; Depressive Disorder; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Monoamine Oxidase Inhibitors; Personality Inventory; Piperidines

1994
MAO inhibitors in panic disorder: clinical effects of treatment with brofaromine. A double blind placebo controlled study.
    Psychopharmacology, 1993, Volume: 112, Issue:4

    Topics: Adult; Agoraphobia; Double-Blind Method; Fear; Female; Follow-Up Studies; Humans; Male; Middle Aged; Monoamine Oxidase Inhibitors; Panic Disorder; Piperidines; Psychiatric Status Rating Scales

1993
A cross-study comparison of the effects of moclobemide and brofaromine on actual driving performance and estimated sleep.
    Clinical neuropharmacology, 1994, Volume: 17 Suppl 1

    Topics: Adult; Automobile Driving; Benzamides; Cross-Over Studies; Double-Blind Method; Doxepin; Female; Humans; Male; Mianserin; Middle Aged; Moclobemide; Monoamine Oxidase Inhibitors; Multivariate Analysis; Piperidines; Psychomotor Performance; Sleep

1994
Brofaromine in non-endogenous major depressed inpatients--results of a preliminary dose-finding trial versus tranylcypromine.
    Pharmacopsychiatry, 1994, Volume: 27, Issue:4

    Topics: Adolescent; Adult; Aged; Depressive Disorder; Double-Blind Method; Female; Humans; Male; Middle Aged; Monoamine Oxidase Inhibitors; Piperidines; Psychiatric Status Rating Scales; Tranylcypromine

1994
Predictors of (non-) response in depressed outpatients treated with a three-phase sequential medication strategy.
    Journal of affective disorders, 1994, Volume: 31, Issue:4

    Topics: Adult; Antidepressive Agents; Cross-Over Studies; Depressive Disorder; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Lithium; Male; Maprotiline; Middle Aged; Monoamine Oxidase Inhibitors; Personality Assessment; Personality Inventory; Piperidines; Treatment Outcome

1994
Brofaromine in treatment-resistant depressed patients--a comparative trial versus tranylcypromine.
    Journal of affective disorders, 1994, Volume: 30, Issue:3

    Topics: Adult; Aged; Depressive Disorder; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Monoamine Oxidase Inhibitors; Personality Inventory; Piperidines; Tranylcypromine

1994
Brofaromine versus lithium addition to maprotiline. A double-blind study in maprotiline refractory depressed outpatients.
    Journal of affective disorders, 1994, Volume: 30, Issue:3

    Topics: Adolescent; Adult; Aged; Depressive Disorder; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Lithium; Male; Maprotiline; Middle Aged; Monoamine Oxidase Inhibitors; Personality Inventory; Piperidines; Prospective Studies; Recurrence

1994
Brofaromine in elderly major depressed patients--a comparative trial versus imipramine.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1993, Volume: 3, Issue:4

    Topics: Aged; Antidepressive Agents; Depressive Disorder; Double-Blind Method; Female; Follow-Up Studies; Humans; Imipramine; Male; Middle Aged; Monoamine Oxidase Inhibitors; Piperidines; Psychiatric Status Rating Scales

1993
Is there a role for selective monoamine oxidase inhibitor therapy in bulimia nervosa? A placebo-controlled trial of brofaromine.
    Journal of clinical psychopharmacology, 1993, Volume: 13, Issue:6

    Topics: Adolescent; Adult; Affect; Attitude; Body Image; Body Weight; Bulimia; Double-Blind Method; Feeding Behavior; Female; Humans; Monoamine Oxidase Inhibitors; Piperidines; Psychiatric Status Rating Scales; Vomiting

1993
The use of the reversible monoamine oxidase-A inhibitor brofaromine in social phobia complicated by panic disorder with or without agoraphobia.
    Journal of clinical psychopharmacology, 1994, Volume: 14, Issue:1

    Topics: Adult; Agoraphobia; Humans; Male; Monoamine Oxidase Inhibitors; Panic Disorder; Phobic Disorders; Piperidines

1994
Brofaromine in depression: a Canadian multicenter placebo trial and a review of standard drug comparative studies.
    Clinical neuropharmacology, 1993, Volume: 16 Suppl 2

    Topics: Adolescent; Adult; Aged; Antidepressive Agents; Canada; Depressive Disorder; Double-Blind Method; Female; Humans; Imipramine; Male; Middle Aged; Monoamine Oxidase Inhibitors; Phenelzine; Piperidines; Psychiatric Status Rating Scales; Tranylcypromine

1993
Reversible monoamine oxidase-A inhibitors in panic disorder.
    Clinical neuropharmacology, 1993, Volume: 16 Suppl 2

    Topics: Agoraphobia; Clomipramine; Double-Blind Method; Humans; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Panic Disorder; Piperidines; Psychiatric Status Rating Scales

1993
The selective reversible monoamine oxidase-A inhibitor brofaromine and sleep.
    Journal of clinical psychopharmacology, 1993, Volume: 13, Issue:4

    Topics: Adult; Aged; Depressive Disorder; Female; Humans; Male; Middle Aged; Monoamine Oxidase Inhibitors; Piperidines; Regression Analysis; Sleep Wake Disorders

1993
Monoamine oxidase inhibitors in resistant major depression. A double-blind comparison of brofaromine and tranylcypromine in patients resistant to tricyclic antidepressants.
    Journal of affective disorders, 1993, Volume: 28, Issue:3

    Topics: Adult; Depressive Disorder; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypotension, Orthostatic; Male; Middle Aged; Monoamine Oxidase Inhibitors; Piperidines; Psychiatric Status Rating Scales; Sleep, REM; Tranylcypromine

1993
Influence of food on the disposition of the monoamine oxidase-A inhibitor brofaromine in healthy volunteers.
    Biopharmaceutics & drug disposition, 1993, Volume: 14, Issue:3

    Topics: Adult; Biological Availability; Chromatography, Gas; Food; Half-Life; Humans; Male; Middle Aged; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Piperidines

1993
Personality traits in social phobia, II: Changes during drug treatment.
    The Journal of clinical psychiatry, 1995, Volume: 56, Issue:12

    Topics: Adult; Comorbidity; Double-Blind Method; Female; Humans; Male; Middle Aged; Monoamine Oxidase Inhibitors; Mood Disorders; Personality Disorders; Phobic Disorders; Piperidines; Placebos; Self Concept; Treatment Outcome

1995
Effect of initial treatment with antidepressants as a predictor of outcome after 8 weeks.
    Psychiatry research, 1995, Sep-29, Volume: 58, Issue:2

    Topics: Adult; Affect; Aged; Antidepressive Agents, Tricyclic; Depressive Disorder; Double-Blind Method; Female; Geriatric Assessment; Humans; Imipramine; Male; Middle Aged; Monoamine Oxidase Inhibitors; Personality Inventory; Piperidines; Prognosis; Treatment Outcome

1995
Social phobia: the clinical efficacy and tolerability of the monoamine oxidase -A and serotonin uptake inhibitor brofaromine. A double-blind placebo-controlled study.
    Acta psychiatrica Scandinavica, 1995, Volume: 92, Issue:5

    Topics: Adult; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Monoamine Oxidase Inhibitors; Personality Inventory; Phobic Disorders; Piperidines; Selective Serotonin Reuptake Inhibitors; Treatment Outcome

1995
A double-blind, randomized, placebo-controlled, multi-center study of brofaromine in the treatment of post-traumatic stress disorder.
    Psychopharmacology, 1995, Volume: 122, Issue:4

    Topics: Adult; Aged; Double-Blind Method; Female; Humans; Male; Middle Aged; Monoamine Oxidase Inhibitors; Piperidines; Stress Disorders, Post-Traumatic

1995
How to assess the onset of antidepressant effect: comparison of global ratings and findings based on depression scales.
    Pharmacopsychiatry, 1996, Volume: 29, Issue:2

    Topics: Adult; Aged; Antidepressive Agents; Antidepressive Agents, Tricyclic; Depressive Disorder; Double-Blind Method; Female; Humans; Imipramine; Male; Middle Aged; Monoamine Oxidase Inhibitors; Piperidines; Psychiatric Status Rating Scales

1996
Different modes of data processing and statistical testing applied to the same set of pharmaco-EEG recordings: effects on the evaluation of a selective and reversible MAO A inhibitor (brofaromine).
    Neuropsychobiology, 1996, Volume: 33, Issue:3

    Topics: Adult; Electroencephalography; Female; Humans; Male; Monoamine Oxidase Inhibitors; Piperidines

1996
Responders and non-responders to drug treatment in social phobia: differences at baseline and prediction of response.
    Journal of affective disorders, 1996, Jun-20, Volume: 39, Issue:1

    Topics: Adult; Arousal; Blood Pressure; Double-Blind Method; Female; Fluvoxamine; Heart Rate; Humans; Male; Middle Aged; Monoamine Oxidase Inhibitors; Personality Inventory; Phobic Disorders; Piperidines; Prognosis; Selective Serotonin Reuptake Inhibitors; Treatment Outcome

1996
A double-blind comparative study of brofaromine and fluvoxamine in outpatients with panic disorder.
    Journal of clinical psychopharmacology, 1996, Volume: 16, Issue:4

    Topics: Adult; Anti-Anxiety Agents; Double-Blind Method; Female; Fluvoxamine; Headache; Humans; Male; Middle Aged; Monoamine Oxidase Inhibitors; Nausea; Panic Disorder; Piperidines; Selective Serotonin Reuptake Inhibitors

1996
Influence of age, frailty and liver function on the pharmacokinetics of brofaromine.
    European journal of clinical pharmacology, 1996, Volume: 49, Issue:5

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Aging; Caffeine; Chromatography, Gas; Cross-Over Studies; Cytochrome P-450 CYP1A2; Female; Frail Elderly; Half-Life; Humans; Liver Function Tests; Male; Monoamine Oxidase Inhibitors; Piperidines; Regression Analysis; Sorbitol

1996
MHPG and heart rate as correlates of nonresponse to drug therapy in panic disorder patients. A preliminary report.
    Psychopharmacology, 1996, Volume: 127, Issue:4

    Topics: Adult; Biomarkers; Blood Pressure; Double-Blind Method; Female; Fluvoxamine; Heart Rate; Humans; Hydrocortisone; Male; Methoxyhydroxyphenylglycol; Middle Aged; Monoamine Oxidase Inhibitors; Panic Disorder; Piperidines; Selective Serotonin Reuptake Inhibitors; Treatment Failure

1996
Brofaromine versus imipramine in in-patients with major depression--a controlled trial.
    Journal of affective disorders, 1997, Volume: 44, Issue:2-3

    Topics: Adolescent; Adult; Aged; Antidepressive Agents, Tricyclic; Depressive Disorder; Dose-Response Relationship, Drug; Double-Blind Method; Female; Hospitalization; Humans; Imipramine; Male; Middle Aged; Monoamine Oxidase Inhibitors; Piperidines; Sleep Wake Disorders

1997
The effects of trazodone on sleep disturbances induced by brofaromine.
    European psychiatry : the journal of the Association of European Psychiatrists, 1999, Volume: 14, Issue:3

    Topics: Dose-Response Relationship, Drug; Double-Blind Method; Electroencephalography; Follow-Up Studies; Humans; Monoamine Oxidase Inhibitors; Piperidines; Selective Serotonin Reuptake Inhibitors; Sleep Initiation and Maintenance Disorders; Sleep, REM; Trazodone; Wakefulness

1999
Predictors of treatment response in patients with posttraumatic stress disorder.
    Progress in neuro-psychopharmacology & biological psychiatry, 2001, Volume: 25, Issue:2

    Topics: Adult; Age of Onset; Analysis of Variance; Disasters; Double-Blind Method; Female; Humans; Male; Monoamine Oxidase Inhibitors; Piperidines; Placebos; Predictive Value of Tests; Prognosis; Psychological Tests; Sex Offenses; Stress Disorders, Post-Traumatic; Treatment Outcome; United States; Warfare

2001

Other Studies

56 other study(ies) available for brofaromine and piperidines

ArticleYear
Monoamine oxidase inhibitors phenelzine and brofaromine increase plasma serotonin and decrease 5-hydroxyindoleacetic acid in patients with major depression: relationship to clinical improvement.
    Journal of clinical psychopharmacology, 1992, Volume: 12, Issue:5

    Topics: Adult; Ambulatory Care; Depressive Disorder; Female; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Monoamine Oxidase Inhibitors; Phenelzine; Piperidines; Serotonin; Treatment Outcome

1992
Displacement of in vivo binding of [3H]brofaromine to rat intestinal monoamine oxidase A by orally administered tyramine.
    European journal of pharmacology, 1992, Jun-05, Volume: 216, Issue:2

    Topics: Administration, Oral; Animals; Binding Sites; Binding, Competitive; Clorgyline; Drug Synergism; Ileum; Intestinal Mucosa; Kinetics; Male; Monoamine Oxidase Inhibitors; Piperidines; Rats; Tyramine

1992
Effects of two different reversible monoamine oxidase-A inhibitors on nociceptive thresholds in the rat.
    European journal of pharmacology, 1992, Aug-14, Volume: 219, Issue:1

    Topics: Animals; Male; Monoamine Oxidase Inhibitors; Pain; Piperidines; Rats; Rats, Inbred Strains; Sensory Thresholds; Serotonin

1992
Effect of the selective MAO-A inhibitors brofaromine, clorgyline and moclobemide on human platelet MAO-B activity.
    Journal of neural transmission. General section, 1992, Volume: 89, Issue:1-2

    Topics: Adult; Benzamides; Blood Platelets; Clorgyline; Female; Humans; Male; Moclobemide; Monoamine Oxidase Inhibitors; Piperidines

1992
Brofaromine in panic disorder: a pilot study with a new reversible inhibitor of monoamine oxidase-A.
    Pharmacopsychiatry, 1992, Volume: 25, Issue:6

    Topics: Adult; Agoraphobia; Female; Humans; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Panic Disorder; Piperidines; Psychiatric Status Rating Scales

1992
Brofaromine, a drug inhibiting MAO-A and 5-HT uptake.
    Clinical neuropharmacology, 1992, Volume: 15 Suppl 1 Pt A

    Topics: Animals; Brain Chemistry; Humans; Monoamine Oxidase Inhibitors; Piperidines; Rats; Serotonin

1992
Clinical pharmacology of reversible MAO-A inhibitors.
    Clinical neuropharmacology, 1992, Volume: 15 Suppl 1 Pt A

    Topics: Benzamides; Depressive Disorder; Humans; Moclobemide; Monoamine Oxidase Inhibitors; Piperidines

1992
Reversible, amine--selective effects of acute and chronic brofaromine treatment in the rat.
    Life sciences, 1992, Volume: 51, Issue:1

    Topics: Animals; Biogenic Amines; Clorgyline; Corpus Striatum; Dose-Response Relationship, Drug; Drug Administration Schedule; Kinetics; Male; Monoamine Oxidase Inhibitors; Phenethylamines; Piperidines; Rats; Rats, Inbred Strains; Tranylcypromine; Tryptamines; Tyramine

1992
Tolerability and antidepressive effect of brofaromine, a short-acting reversible MAO inhibitor--an open study.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1991, Volume: 1, Issue:2

    Topics: Adult; Aged; Blood Pressure; Depressive Disorder; Female; Humans; Male; Middle Aged; Monoamine Oxidase Inhibitors; Piperidines; Psychiatric Status Rating Scales; Pulse

1991
The inhibition of monoamine oxidase by brofaromine.
    Biochemical pharmacology, 1991, Jun-15, Volume: 41, Issue:12

    Topics: Animals; Chromatography, Thin Layer; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Kinetics; Mitochondria, Liver; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Myocardium; Pargyline; Piperidines; Rats; Serum Albumin, Bovine; Temperature

1991
Brofaromine vs. maprotiline plus lithium in treatment-resistant depressed outpatients.
    Psychiatry research, 1991, Volume: 36, Issue:3

    Topics: Depressive Disorder; Drug Therapy, Combination; Humans; Lithium; Maprotiline; Monoamine Oxidase Inhibitors; Pilot Projects; Piperidines; Psychiatric Status Rating Scales

1991
Brofaromine (CGP 11 305 A): estimation of plasma concentrations by a biologic technique as compared to liquid chromatography.
    Journal of neural transmission. Supplementum, 1990, Volume: 32

    Topics: Adult; Aged; Chromatography, Liquid; Depressive Disorder; Female; Humans; In Vitro Techniques; Male; Middle Aged; Mitochondria; Monoamine Oxidase Inhibitors; Piperidines; Placenta; Pregnancy

1990
Dorsal raphe microinjection of 5-HT and indirect 5-HT agonists induces feeding in rats.
    European journal of pharmacology, 1990, Aug-10, Volume: 184, Issue:2-3

    Topics: Animals; Feeding Behavior; Fenfluramine; Male; Microinjections; Monoamine Oxidase Inhibitors; Piperidines; Raphe Nuclei; Rats; Receptors, Serotonin; Serotonin; Zimeldine

1990
The effect of repeated treatment with brofaromine, moclobemide and deprenyl on alpha 1-adrenergic and dopaminergic receptors in the rat brain.
    Neuroscience letters, 1990, Jan-01, Volume: 108, Issue:1-2

    Topics: Animals; Benzamides; Brain; Male; Moclobemide; Phenethylamines; Piperidines; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Dopamine; Selegiline

1990
Binding of [3H]brofaromine to monoamine oxidase A in vivo: displacement by clorgyline and moclobemide.
    European journal of pharmacology, 1990, May-16, Volume: 180, Issue:2-3

    Topics: Animals; Benzamides; Binding, Competitive; Biogenic Monoamines; Clorgyline; In Vitro Techniques; Male; Microsomes, Liver; Moclobemide; Monoamine Oxidase; Piperidines; Proadifen; Propylamines; Rats; Rats, Inbred Strains; Tissue Distribution

1990
Brofaromine (CGP 11 305 A) in treatment of depression: biological estimation of plasma concentrations.
    Pharmacopsychiatry, 1990, Volume: 23, Issue:3

    Topics: Adult; Aged; Depressive Disorder; Female; Humans; Male; Middle Aged; Mitochondria; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Piperidines; Placenta; Psychiatric Status Rating Scales

1990
Enhancement of 5-HT-induced anorexia: a test of the reversibility of monoamine oxidase inhibitors.
    Psychopharmacology, 1989, Volume: 98, Issue:2

    Topics: Animals; Benzamides; Clorgyline; Drug Synergism; Feeding Behavior; Male; Moclobemide; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Piperidines; Rats; Rats, Inbred Strains; Serotonin

1989
[Comparison of the new MAO-A inhibitors moclobemide, brofaromine and toloxatone with tranylcypromine in an animal experiment: significance for clinical practice].
    Psychiatrische Praxis, 1989, Volume: 16 Suppl 1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antidepressive Agents; Benzamides; Blood Pressure; Heart Rate; Moclobemide; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Piperidines; Rats; Serotonin; Structure-Activity Relationship; Tranylcypromine

1989
[Hypertensive crises with reversible inhibitors of monoamine oxidases? Results of tyramine interaction studies].
    Psychiatrische Praxis, 1989, Volume: 16 Suppl 1

    Topics: Administration, Oral; Adult; Benzamides; Blood Pressure; Female; Humans; Hypertension; Male; Moclobemide; Monoamine Oxidase Inhibitors; Piperidines; Risk Factors; Tyramine

1989
Determination of the new monoamine oxidase inhibitor brofaromine and its major metabolite in biological material by gas chromatography with electron-capture detection.
    Journal of chromatography, 1989, Mar-17, Volume: 488, Issue:1

    Topics: Chemical Phenomena; Chemistry; Chromatography, Gas; Electrochemistry; Humans; Kinetics; Monoamine Oxidase Inhibitors; Piperidines

1989
Tyramine potentiation during treatment with MAO inhibitors: brofaromine and moclobemide vs irreversible inhibitors.
    Journal of neural transmission. Supplementum, 1989, Volume: 28

    Topics: Adult; Benzamides; Blood Pressure; Drug Synergism; Female; Humans; Male; Moclobemide; Monoamine Oxidase Inhibitors; Piperidines; Time Factors; Tyramine

1989
The reversible MAO inhibitor, brofaromine, inhibits serotonin uptake in vivo.
    European journal of pharmacology, 1989, Oct-10, Volume: 169, Issue:2-3

    Topics: Animals; Brain; Imipramine; In Vitro Techniques; Male; Monoamine Oxidase Inhibitors; Piperidines; Proadifen; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists

1989
Monoamine oxidase inhibition by phenelzine and brofaromine in healthy volunteers.
    Clinical pharmacology and therapeutics, 1989, Volume: 45, Issue:3

    Topics: Adult; Biological Availability; Blood Pressure; Heart Rate; Humans; Male; Methoxyhydroxyphenylglycol; Monoamine Oxidase Inhibitors; Phenelzine; Piperidines; Tryptamines; Tyramine; Vanilmandelic Acid

1989
Effects of brofaremine (CGP 11 305A), a short-acting, reversible, and selective inhibitor of MAO-A on sleep, nocturnal penile tumescence and nocturnal hormonal secretion in three healthy volunteers.
    Psychopharmacology, 1987, Volume: 92, Issue:1

    Topics: Adult; Electroencephalography; Hormones; Humans; Male; Monoamine Oxidase Inhibitors; Penile Erection; Piperidines; Sleep; Sleep, REM

1987
Selective inhibition of MAO-A, not MAO-B, results in antidepressant-like effects on DRL 72-s behavior.
    Psychopharmacology, 1988, Volume: 96, Issue:2

    Topics: Animals; Antidepressive Agents; Clorgyline; Conditioning, Operant; Dose-Response Relationship, Drug; Male; Monoamine Oxidase Inhibitors; Pargyline; Piperidines; Rats; Rats, Inbred Strains; Reinforcement Schedule; Selegiline

1988
Reversible, enzyme-activated monoamine oxidase inhibitors: new advances.
    Pharmacological research communications, 1988, Volume: 20 Suppl 4

    Topics: Animals; Benzamides; Brain; Clorgyline; Humans; In Vitro Techniques; Male; Moclobemide; Monoamine Oxidase Inhibitors; Phenelzine; Picolinic Acids; Piperidines; Rats; Selegiline

1988
Potentiation of tyramine pressor responses in conscious rats by reversible inhibitors of monoamine oxidase.
    Journal of neural transmission. Supplementum, 1988, Volume: 26

    Topics: Animals; Benzamides; Blood Pressure; Clorgyline; Drug Synergism; Male; Moclobemide; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Phenethylamines; Piperidines; Rats; Rats, Inbred Strains; Tyramine

1988
Quantitative determination of brofaromin in human plasma after high performance liquid chromatographic separation.
    Archiv der Pharmazie, 1988, Volume: 321, Issue:6

    Topics: Chromatography, High Pressure Liquid; Humans; Monoamine Oxidase Inhibitors; Piperidines

1988
Effect of brofaromine and pargyline on human plasma melatonin concentrations.
    Progress in neuro-psychopharmacology & biological psychiatry, 1988, Volume: 12, Issue:1

    Topics: Administration, Oral; Adult; Circadian Rhythm; Dose-Response Relationship, Drug; Humans; Melatonin; Monoamine Oxidase Inhibitors; Pargyline; Piperidines

1988
Results of an open clinical trial of brofaromine (CGP 11 305 A), a competitive, selective, and short-acting inhibitor of MAO-A in major endogenous depression.
    Pharmacopsychiatry, 1987, Volume: 20, Issue:6

    Topics: Adult; Aged; Blood Platelets; Depressive Disorder; Dexamethasone; Electroencephalography; Female; Humans; Male; Middle Aged; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Personality Assessment; Piperidines; Serotonin; Sleep, REM; Tyramine

1987
Short-acting novel MAO inhibitors: in vitro evidence for the reversibility of MAO inhibition by moclobemide and Ro 16-6491.
    Naunyn-Schmiedeberg's archives of pharmacology, 1987, Volume: 335, Issue:1

    Topics: Animals; Benzamides; Brain; Brain Chemistry; Dialysis; In Vitro Techniques; Liver; Male; Moclobemide; Monoamine Oxidase Inhibitors; Piperidines; Rats; Tyramine

1987
Dissociation of REM sleep and nocturnal penile tumescence in volunteers treated with brofaremine.
    Psychiatry research, 1987, Volume: 20, Issue:2

    Topics: Adult; Humans; Male; Penile Erection; Piperidines; Sleep, REM

1987
On the reversibility of reversible MAO inhibitors.
    Naunyn-Schmiedeberg's archives of pharmacology, 1985, Volume: 329, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benzamides; Brain; Clorgyline; Dopamine; Female; Homovanillic Acid; Kinetics; Liver; Moclobemide; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Phenethylamines; Piperidines; Rats; Rats, Inbred Strains; Serotonin

1985
Characterization of a new, short-acting and specific inhibitor of type A monoamine oxidase.
    Modern problems of pharmacopsychiatry, 1983, Volume: 19

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Amines; Brain; Brain Chemistry; Female; Hemodynamics; Hydroxyindoleacetic Acid; Liver; Male; Methoxyhydroxyphenylglycol; Monoamine Oxidase Inhibitors; Piperidines; Rats; Rats, Inbred Strains; Serotonin Antagonists; Synaptosomes; Tranylcypromine

1983
Effects of CGP 11305 A, a new reversible and selective inhibitor of MAO A, on biogenic amine levels and metabolism in the rat brain.
    Naunyn-Schmiedeberg's archives of pharmacology, 1983, Volume: 324, Issue:1

    Topics: Animals; Biogenic Amines; Brain; Brain Chemistry; Clorgyline; Dopamine; Female; Hydroxyindoleacetic Acid; In Vitro Techniques; Monoamine Oxidase Inhibitors; Myocardium; Norepinephrine; Piperidines; Rats; Serotonin; Tryptophan

1983
Reversibility of the interaction of CGP 11305 A with MAO A in vivo.
    European journal of pharmacology, 1983, Oct-14, Volume: 94, Issue:1-2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Clorgyline; Dopamine; Female; Homovanillic Acid; Hydroxyindoleacetic Acid; Liver; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Piperidines; Rats; Serotonin; Tetrabenazine

1983
Urinary excretion of O-methylated catecholamines, tyramine and phenyl-ethylamine by volunteers treated with tranylcypromine and CGP 11305 A.
    European journal of clinical pharmacology, 1983, Volume: 25, Issue:3

    Topics: Adult; Amphetamine; Epinephrine; Female; Humans; Male; Metanephrine; Monoamine Oxidase Inhibitors; Normetanephrine; Phenethylamines; Piperidines; Tranylcypromine; Tyramine

1983
The monoamine oxidase inhibiting properties of CGP 11305 A.
    European journal of pharmacology, 1983, Oct-14, Volume: 94, Issue:1-2

    Topics: Animals; Brain; Dialysis; Female; Kinetics; Mitochondria, Liver; Monoamine Oxidase Inhibitors; Piperidines; Rats; Time Factors

1983
Monoamine oxidase inhibition in healthy volunteers by CGP 11305 A, a new specific inhibitor of MAO-A.
    Modern problems of pharmacopsychiatry, 1983, Volume: 19

    Topics: Adult; Biogenic Amines; Blood Pressure; Female; Hemodynamics; Humans; Kinetics; Male; Monoamine Oxidase Inhibitors; Piperidines; Time Factors; Tranylcypromine

1983
In vivo evidence for the reversible action of the monoamine oxidase inhibitor brofaromine on 5-hydroxytryptamine release in rat brain.
    Naunyn-Schmiedeberg's archives of pharmacology, 1995, Volume: 351, Issue:5

    Topics: Animals; Brain; Dose-Response Relationship, Drug; Frontal Lobe; Hydroxyindoleacetic Acid; Male; Microdialysis; Monoamine Oxidase Inhibitors; Piperidines; Rats; Rats, Wistar; Serotonin; Time Factors

1995
Reversible and selective inhibitors of monoamine oxidase A in mental and other disorders.
    Acta psychiatrica Scandinavica. Supplementum, 1995, Volume: 386

    Topics: Alzheimer Disease; Antidepressive Agents, Tricyclic; Attention Deficit Disorder with Hyperactivity; Benzamides; Humans; Moclobemide; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Panic Disorder; Phobic Disorders; Piperidines

1995
Monoamine oxidase inhibition by the MAO-A inhibitors brofaromine and clorgyline in healthy volunteers.
    Journal of neural transmission. General section, 1994, Volume: 95, Issue:3

    Topics: Administration, Oral; Adult; Blood Pressure; Clorgyline; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Synergism; Female; Humans; Hypertension; Infusions, Intravenous; Male; Methoxyhydroxyphenylglycol; Monoamine Oxidase; Norepinephrine; Piperidines; Reference Values; Tryptamines; Tyramine

1994
Correlations of plasma and urinary phenylacetic acid and phenylethylamine concentrations with eating behavior and mood rating scores in brofaromine-treated women with bulimia nervosa.
    Journal of psychiatry & neuroscience : JPN, 1994, Volume: 19, Issue:4

    Topics: Adult; Bulimia; Depressive Disorder; Female; Humans; Monoamine Oxidase Inhibitors; Phenylacetates; Piperidines; Placebos; Psychiatric Status Rating Scales; Severity of Illness Index; Single-Blind Method

1994
The effects of brofaromine, a reversible MAO-A inhibitor, on extracellular serotonin in the raphe nuclei and frontal cortex of freely moving rats.
    Journal of neural transmission. Supplementum, 1994, Volume: 41

    Topics: Animals; Dose-Response Relationship, Drug; Extracellular Space; Frontal Lobe; Injections, Subcutaneous; Microdialysis; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Piperidines; Raphe Nuclei; Rats; Serotonin

1994
Adverse interaction of cyproheptadine with serotonergic antidepressants.
    The Journal of clinical psychiatry, 1994, Volume: 55, Issue:7

    Topics: Acute Disease; Cyproheptadine; Depressive Disorder; Drug Interactions; Female; Fluoxetine; Humans; Middle Aged; Monoamine Oxidase Inhibitors; Paranoid Disorders; Piperidines; Recurrence

1994
Role of cytochrome P4502D6 in the metabolism of brofaromine. A new selective MAO-A inhibitor.
    European journal of clinical pharmacology, 1993, Volume: 45, Issue:3

    Topics: Adult; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Female; Humans; Male; Mixed Function Oxygenases; Monoamine Oxidase Inhibitors; Phenotype; Piperidines; Quinidine

1993
The advent of a new generation of monoamine oxidase inhibitor antidepressants: pharmacologic studies with moclobemide and brofaromine.
    Clinical neuropharmacology, 1993, Volume: 16 Suppl 2

    Topics: Animals; Antidepressive Agents; Benzamides; Blood Pressure; Clorgyline; Desipramine; Heart Rate; Kidney; Moclobemide; Monoamine Oxidase Inhibitors; Piperidines; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System

1993
Effects of monoamine oxidase inhibitors on the acid metabolites of some trace amines and of dopamine in the rat striatum.
    Biochemical pharmacology, 1993, Mar-24, Volume: 45, Issue:6

    Topics: 3,4-Dihydroxyphenylacetic Acid; Amines; Animals; Corpus Striatum; Dopamine; Male; Methyldopa; Monoamine Oxidase Inhibitors; Phenylacetates; Piperidines; Rats; Rats, Wistar; Selegiline

1993
Monoamine oxidase-A inhibitors and dopamine metabolism in rat caudatus: evidence that an increased cytosolic level of dopamine displaces reversible monoamine oxidase-A inhibitors in vivo.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 265, Issue:1

    Topics: 2H-Benzo(a)quinolizin-2-ol, 2-Ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-; Animals; Benzamides; Biogenic Monoamines; Caudate Nucleus; Cytosol; Dopamine; Male; Moclobemide; Monoamine Oxidase Inhibitors; Piperidines; Rats; Serotonin; Tetrodotoxin

1993
Metabolism of the new MAO-A inhibitor brofaromine in poor and extensive metabolizers of debrisoquine.
    Journal of pharmaceutical and biomedical analysis, 1993, Volume: 11, Issue:3

    Topics: Administration, Oral; Adult; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Debrisoquin; Female; Humans; Male; Mixed Function Oxygenases; Monoamine Oxidase Inhibitors; Piperidines

1993
Radiosynthesis of [11C]brofaromine, a potential tracer for imaging monoamine oxidase A.
    Nuclear medicine and biology, 1996, Volume: 23, Issue:3

    Topics: Animals; Benzamides; Brain; Carbon Radioisotopes; Clorgyline; Female; Hydrocarbons, Iodinated; Indicators and Reagents; Isoenzymes; Isotope Labeling; Macaca mulatta; Moclobemide; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Piperidines; Tomography, Emission-Computed

1996
Adaptative changes of the serotonergic system after antidepressant treatments.
    Advances in experimental medicine and biology, 1996, Volume: 398

    Topics: Analysis of Variance; Animals; Antidepressive Agents; Clomipramine; Clorgyline; Fluvoxamine; Frontal Lobe; Hydroxyindoleacetic Acid; Imipramine; Microdialysis; Monoamine Oxidase Inhibitors; Piperidines; Pyrimidines; Raphe Nuclei; Rats; Serotonin; Stereotaxic Techniques; Tranylcypromine; Tryptophan

1996
Regional action of brofaromine on rat brain MAO-A and MAO-B.
    Progress in neuro-psychopharmacology & biological psychiatry, 1998, Volume: 22, Issue:7

    Topics: Animals; Brain; Cerebellum; Corpus Striatum; Hippocampus; Hypothalamus; Isoenzymes; Kinetics; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Organ Specificity; Piperidines; Prefrontal Cortex; Rats; Rats, Wistar

1998
Inhibition of platelet MAO-B by kava pyrone-enriched extract from Piper methysticum Forster (kava-kava).
    Pharmacopsychiatry, 1998, Volume: 31, Issue:5

    Topics: Amitriptyline; Anti-Anxiety Agents; Blood Platelets; Humans; Imipramine; Kava; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Piperidines; Plant Extracts; Plants, Medicinal; Pyrones

1998
Comparison of neurochemical effects of the monoamine oxidase inhibitors phenelzine, moclobemide and brofaromine in the rat after short- and long-term administration.
    Journal of affective disorders, 2000, Volume: 58, Issue:2

    Topics: Animals; Brain; Down-Regulation; Long-Term Care; Male; Moclobemide; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Phenelzine; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin

2000
Design, synthesis, and biological activities of pyrrolylethanoneamine derivatives, a novel class of monoamine oxidases inhibitors.
    Journal of medicinal chemistry, 2005, Jun-30, Volume: 48, Issue:13

    Topics: Drug Design; Kinetics; Models, Molecular; Molecular Structure; Monoamine Oxidase Inhibitors; Oxazolidinones; Piperazines; Piperidines; Pyrrolidines; Structure-Activity Relationship

2005