brodimoprim has been researched along with epiroprim in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 4 (50.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Richards, WG; So, SS | 1 |
| Hansch, C; Li, RL; Poe, M; Selassie, CD | 1 |
| Debnath, G; Fang, ZX; Hansch, C; Kaufman, BT; Klein, TE; Langridge, R; Li, RL; Selassie, CD | 1 |
| Fang, ZX; Hansch, C; Kaufman, BT; Klein, T; Langridge, R; Li, RL; Selassie, CD | 1 |
| Papoulis, AT; Queener, SF; Rosowsky, A | 1 |
| Loukas, YL | 1 |
| Bera, S; Mondal, D | 1 |
| Dhople, AM | 1 |
1 review(s) available for brodimoprim and epiroprim
| Article | Year |
|---|---|
Insights of synthetic analogues of anti-leprosy agents.
Topics: Humans; Leprostatic Agents; Leprosy; Structure-Activity Relationship | 2019 |
7 other study(ies) available for brodimoprim and epiroprim
| Article | Year |
|---|---|
Application of neural networks: quantitative structure-activity relationships of the derivatives of 2,4-diamino-5-(substituted-benzyl)pyrimidines as DHFR inhibitors.
Topics: Drug Design; Folic Acid Antagonists; Neural Networks, Computer; Pyrimidines; Regression Analysis; Structure-Activity Relationship | 1992 |
On the optimization of hydrophobic and hydrophilic substituent interactions of 2,4-diamino-5-(substituted-benzyl)pyrimidines with dihydrofolate reductase.
Topics: Diamines; Escherichia coli; Folic Acid Antagonists; Kinetics; Lacticaseibacillus casei; Molecular Structure; Protein Binding; Pyrimidines; Structure-Activity Relationship | 1991 |
On the structure selectivity problem in drug design. A comparative study of benzylpyrimidine inhibition of vertebrate and bacterial dihydrofolate reductase via molecular graphics and quantitative structure-activity relationships.
Topics: Animals; Chemical Phenomena; Chemistry; Chickens; Drug Design; Folic Acid Antagonists; Lacticaseibacillus casei; Liver; Pyrimidines; Structure-Activity Relationship; X-Ray Diffraction | 1989 |
Inhibition of chicken liver dihydrofolate reductase by 5-(substituted benzyl)-2,4-diaminopyrimidines. A quantitative structure-activity relationship and graphics analysis.
Topics: Animals; Chickens; Crystallography; Enzyme Inhibitors; Folic Acid Antagonists; Liver; Mathematics; Models, Molecular; Pyrimidines; Structure-Activity Relationship; Trimethoprim; X-Ray Diffraction | 1986 |
2,4-Diaminothieno[2,3-d]pyrimidine lipophilic antifolates as inhibitors of Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase.
Topics: Animals; Enzyme Inhibitors; Folic Acid Antagonists; Liver; Magnetic Resonance Spectroscopy; Pneumocystis; Pyrimidines; Rats; Tetrahydrofolate Dehydrogenase; Thiophenes; Toxoplasma | 1997 |
Adaptive neuro-fuzzy inference system: an instant and architecture-free predictor for improved QSAR studies.
Topics: Algorithms; Folic Acid Antagonists; Multivariate Analysis; Pyrimidines; Quantitative Structure-Activity Relationship; Regression Analysis; Tetrahydrofolate Dehydrogenase | 2001 |
In vitro activity of epiroprim, a dihydrofolate reductase inhibitor, singly and in combination with brodimoprim and dapsone, against Mycobacterium leprae.
Topics: Cell-Free System; Dapsone; Folic Acid Antagonists; Leprostatic Agents; Microbial Sensitivity Tests; Mycobacterium leprae; Trimethoprim | 1999 |