brobactam has been researched along with penicillanic acid in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (66.67) | 18.7374 |
| 1990's | 6 (28.57) | 18.2507 |
| 2000's | 1 (4.76) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andrews, JM; Johnson, J; O'Sullivan, N; Wise, R | 1 |
| Keiding, J; Melchior, NH | 1 |
| Agapova, NN; Changov, LS; Ivanova, ZT; Mondeshka, DM; Tsenkova, MM; Vasileva-Lukanova, BK | 1 |
| De Meester, F; Dive, G; Frère, JM; Matagne, A | 1 |
| Chojnowski, W; Jastalska, D; Lupicki, W; Pajchel, G; Zapaśnik, M | 1 |
| Knap, AK; Pratt, RF | 1 |
| Kissmeyer-Nielsen, AM | 1 |
| Claes, PJ; De Meester, F; Piette, JL; Roets, E; Thomis, J; Vanderhaeghe, H | 1 |
| Coyette, J; De Meester, F; Frere, JM; Galleni, M; Joris, B; Reckinger, G; Van Beeumen, J | 1 |
| Neu, HC | 2 |
| Houben, AW; Stobberingh, EE; van Boven, CP | 1 |
| Belasco, JG; Charnas, RL; Fisher, J; Khosla, S; Knowles, JR | 1 |
| Cohen, SA; Loosemore, MJ; Pratt, RF | 1 |
| Knott-Hunziker, V; Orlek, BS; Sammes, PG; Waley, SG | 2 |
| Andrews, JM; Patel, N; Wise, R | 1 |
| Andrews, JM; Wise, R; Wolstenholme, MR; Woodcock, JM | 1 |
| Labia, R; Mariotte-Boyer, S; Nicolas-Chanoine, MH | 1 |
| Calcagno, ML; Danelon, G; Gutkind, G; Mascaretti, O; Mata, EG; Power, P; Radice, M | 1 |
| Balsamini, C; Bedini, A; Citterio, B; Di Giacomo, B; Di Modugno, E; Giorgi, L; Tarzia, G; Tontini, A | 1 |
1 review(s) available for brobactam and penicillanic acid
| Article | Year |
|---|---|
The role of beta-lactamase inhibitors in chemotherapy.
Topics: Animals; Anti-Bacterial Agents; Bacterial Infections; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Chemical Phenomena; Chemistry; Clavulanic Acid; Clavulanic Acids; Gram-Negative Bacteria; Humans; Lactams; Penicillanic Acid; Sulfones | 1985 |
20 other study(ies) available for brobactam and penicillanic acid
| Article | Year |
|---|---|
Pharmacokinetics and tissue penetration of ampicillin and brobactam following oral administration of 2085P.
Topics: Administration, Oral; Adult; Ampicillin; beta-Lactamase Inhibitors; Drug Therapy, Combination; Humans; Male; Penicillanic Acid; Pivampicillin | 1992 |
In-vitro evaluation of ampicillin/brobactam and comparison with other beta-lactam antibiotics.
Topics: Ampicillin; Anti-Bacterial Agents; Bacteria; beta-Lactamase Inhibitors; beta-Lactamases; Drug Resistance, Microbial; Drug Therapy, Combination; Evaluation Studies as Topic; Penicillanic Acid | 1991 |
[A simple method of synthesis of S-sulfoxides of penicillanic acid and 6-alpha-bromo[chloro]-penicillanic acids].
Topics: beta-Lactamase Inhibitors; Hydrogen Peroxide; Penicillanic Acid; Spectrophotometry, Infrared; Sulfoxides | 1990 |
Unexpected influence of ionic strength on branched-pathway interactions between beta-lactamases and beta-halogenopenicillanates.
Topics: beta-Lactamase Inhibitors; beta-Lactamases; Kinetics; Osmolar Concentration; Penicillanic Acid | 1989 |
[Changes in the sensitivity of clinical strains of Staphylococcus aureus caused by cefamandole, cefoperazone and 6-alpha-bromopenicillanic acid sulfone in vitro].
Topics: Cefamandole; Cefoperazone; Drug Resistance, Microbial; In Vitro Techniques; Penicillanic Acid; Staphylococcus aureus | 1987 |
Inactivation of the thiol RTEM-1 beta-lactamase by 6-beta-bromopenicillanic acid. Identity of the primary active-site nucleophile.
Topics: beta-Lactamase Inhibitors; beta-Lactamases; Binding Sites; Chemical Phenomena; Chemistry; Clavulanic Acid; Clavulanic Acids; Kinetics; Penicillanic Acid; Spectrophotometry | 1987 |
Determination of 6 beta-bromopenicillanic acid (brobactam) in human serum and urine by high-performance liquid chromatography.
Topics: Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Penicillanic Acid; Spectrophotometry, Ultraviolet | 1988 |
Synthesis of deuterium- and tritium-labeled 6 beta-bromopenicillanic acid.
Topics: Chemical Phenomena; Chemistry; Deuterium; Isomerism; Penicillanic Acid; Tritium | 1985 |
The beta-lactamase of Enterobacter cloacae P99. Chemical properties, N-terminal sequence and interaction with 6 beta-halogenopenicillanates.
Topics: Amino Acid Sequence; Amino Acids; beta-Lactamase Inhibitors; beta-Lactamases; Enterobacter; Enterobacteriaceae; Kinetics; Penicillanic Acid; Spectrophotometry; Tryptophan | 1985 |
In vitro activity of ampicillin alone and in combination with different concentrations of 6 beta-bromopenicillanic acid, clavulanic acid and mecillinam.
Topics: Amdinocillin; Ampicillin; beta-Lactamase Inhibitors; Clavulanic Acid; Clavulanic Acids; Drug Combinations; Drug Interactions; Drug Synergism; Enterobacteriaceae; Microbial Sensitivity Tests; Penicillanic Acid | 1987 |
Beta-lactamase inactivation by mechanism-based reagents.
Topics: Anti-Bacterial Agents; Bacteria; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Clavulanic Acid; Lactams; Penicillanic Acid; Sulbactam | 1980 |
Inactivation of Bacillus cereus beta-lactamase I by 6 beta-bromopenicillanic acid: kinetics.
Topics: Bacillus cereus; beta-Lactamase Inhibitors; Hydrogen-Ion Concentration; Kinetics; Penicillanic Acid; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tritium | 1980 |
On the chemistry of beta-lactamase inhibition by 6 beta-bromopenicillanic acid.
Topics: Bacillus cereus; beta-Lactamase Inhibitors; Chemical Phenomena; Chemistry; Penicillanic Acid | 1980 |
6-beta-bromo- and 6-beta-iodo penicillanic acid, two novel beta-lactamase inhibitors.
Topics: Ampicillin; Bacteria; beta-Lactamase Inhibitors; beta-Lactams; Clavulanic Acid; Penicillanic Acid | 1981 |
beta-Lactamase inhibitory activity of iodopenicillanate and bromopenicillanate.
Topics: Ampicillin; Bacteria; beta-Lactamase Inhibitors; Cefazolin; Penicillanic Acid | 1983 |
Kinetics of inactivation of beta-lactamase I by 6 beta-bromopenicillanic acid.
Topics: Bacillus cereus; beta-Lactamase Inhibitors; Kinetics; Mathematics; Penicillanic Acid; Protein Binding; Spectrophotometry, Ultraviolet | 1980 |
Determination of 6-beta-bromopenicillanic acid (brobactam) in human serum by high-performance liquid chromatography (HPLC) using solid phase extraction for sample preparation.
Topics: beta-Lactamase Inhibitors; Chromatography, High Pressure Liquid; Humans; Klebsiella pneumoniae; Penicillanic Acid; Spectrophotometry, Ultraviolet | 1994 |
A kinetic study of NMC-A beta-lactamase, an Ambler class A carbapenemase also hydrolyzing cephamycins.
Topics: Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; Binding Sites; Cephamycins; Clavulanic Acid; Clavulanic Acids; Enterobacter cloacae; Enzyme Inhibitors; Escherichia coli; Hydrolysis; Kinetics; Molecular Structure; Penicillanic Acid; Recombinant Proteins; Substrate Specificity; Sulbactam; Tazobactam | 1996 |
Comparative in-vitro activities of GD-40 and other beta-lactamase inhibitors against TEM-1 and SHV-2 beta-lactamases.
Topics: beta-Lactamase Inhibitors; beta-Lactamases; Clavulanic Acid; Enzyme Inhibitors; Penicillanic Acid; Sulbactam; Tazobactam | 1998 |
Synthesis and biological evaluation of 6-bromo-6-substituted penicillanic acid derivatives as beta-lactamase inhibitors.
Topics: beta-Lactamase Inhibitors; beta-Lactamases; Drug Evaluation, Preclinical; Enzyme Inhibitors; Penicillanic Acid | 2002 |